Kylie Gorringe

The TP53 mutation rate differs in breast cancers that arise in women with high or low mammographic density

Dane Cheasley, Lisa Devereux, Siobhan Hughes, Carolyn Nickson, Pietro Procopio, Grant Lee, Na Li, Vicki Pridmore, Kenneth Elder, G Bruce Mann, Tanjina Kader, Simone M Rowley, Stephen B Fox, David Byrne, Hugo Saunders, Kenji M Fujihara, Belle Lim, Kylie L Gorringe, Ian G Campbell

Journal article  |  2020  |  npj Breast Cancer

Mammographic density (MD) influences breast cancer risk, but how this is mediated is unknown. Molecular differences between breast..

Molecular comparison of pure ovarian fibroma with serous benign ovarian tumours.

Sally M Hunter, Genevieve V Dall, Maria A Doyle, Richard Lupat, Jason Li, Prue Allan, Simone M Rowley, David Bowtell, undefined AOCS, Ian G Campbell, Kylie L Gorringe

Journal article  |  2020  |  BMC Research Notes

OBJECTIVE: Ovarian fibromas and adenofibromas are rare ovarian tumours. They are benign tumours composed of spindle-like stromal c..

CDK4/6 and MEK inhibitor combination in low-grade serous ovarian cancer cell lines.

Joshua Hoenisch, Hannah Kim, Amy Dawson, Nicole Lam, Dane A Cheasley, Kylie Gorringe, Ian Campbell, David G Huntsman, Gabriel DiMattia, Martin Kobel, Marta Llaurado Fernandez, Mark S Carey

Conference Proceedings  |  2020  |  CLINICAL CANCER RESEARCH

Germline whole exome sequencing of a family with appendiceal mucinous tumours presenting with pseudomyxoma peritonei

Mei Sim Lung, Catherine A Mitchell, Maria A Doyle, Andrew C Lynch, Kylie L Gorringe, David DL Bowtell, Ian G Campbell, Alison H Trainer

Journal article  |  2020  |  BMC Cancer

BACKGROUND: Familial cases of appendiceal mucinous tumours (AMTs) are extremely rare and the underlying genetic aetiology uncertai..

Exome sequencing of familial high-grade serous ovarian carcinoma reveals heterogeneity for rare candidate susceptibility genes

Deepak N Subramanian, Magnus Zethoven, Simone McInerny, James A Morgan, Simone M Rowley, Jue Er Amanda Lee, Na Li, Kylie L Gorringe, Paul A James, Ian G Campbell

Journal article  |  2020  |  Nature Communications

High-grade serous ovarian carcinoma (HGSOC) has a significant hereditary component, approximately half of which cannot be explaine..

The prognostic significance of immune microenvironment in breast ductal carcinoma in situ

Michael S Toss, Asima Abidi, Dorothea Lesche, Chitra Joseph, Sakshi Mahale, Hugo Saunders, Tanjina Kader, Islam M Miligy, Andrew R Green, Kylie L Gorringe, Emad A Rakha

Journal article  |  2020  |  British Journal of Cancer

BACKGROUND: The role of different subtypes of tumour infiltrating lymphocytes (TILs) in breast ductal carcinoma in situ (DCIS) is ..

The genetic architecture of breast papillary lesions as a predictor of progression to carcinoma

Tanjina Kader, Kenneth Elder, Magnus Zethoven, Timothy Semple, Prue Hill, David L Goode, Niko Thio, Dane Cheasley, Simone M Rowley, David J Byrne, Jia-Min Pang, Islam M Miligy, Andrew R Green, Emad A Rakha, Stephen B Fox, G Bruce Mann, Ian G Campbell, Kylie L Gorringe

Journal article  |  2020  |  npj Breast Cancer

Intraductal papillomas (IDP) are challenging breast findings because of their variable risk of progression to malignancy. The mole..

A Refined Cut-Off for p53 Immunohistochemistry Improves Prediction of TP53 Mutation Status in Ovarian Mucinous Tumors: Implications for Outcome Analyses

Eun-Young Kang, Dane Cheasley, Cecile Le Page, Matthew Wakefield, Yoland Antill, Kylie Gorringe, Martin Kobel

Conference Proceedings  |  2020  |  Modern Pathology

Therapeutic options for mucinous ovarian carcinoma

Kylie L Gorringe, Dane Cheasley, Matthew J Wakefield, Georgina L Ryland, Prue E Allan, Kathryn Alsop, Kaushalya C Amarasinghe, Sumitra Ananda, David DL Bowtell, Michael Christie, Yoke-Eng Chiew, Michael Churchman, Anna DeFazio, Sian Fereday, C Blake Gilks, Charlie Gourley, Alison M Hadley, Joy Hendley, Sally M Hunter, Scott H Kaufmann, et al.

Journal article  |  2020  |  Gynecologic Oncology

OBJECTIVE: Mucinous ovarian carcinoma (MOC) is an uncommon ovarian cancer histotype that responds poorly to conventional chemother..

Prognostic significance of cathepsin V (CTSV/CTSL2) in breast ductal carcinoma in situ

Michael Toss, Islam Miligy, Kylie Gorringe, Karuna Mittal, Ritu Aneja, Ian Ellis, Andrew Green, Emad Rakha

Journal article  |  2020  |  Journal of Clinical Pathology

AIMS: Cathepsin V (CTSV/CTSL2) is a lysosomal cysteine proteinase and plays a role in extracellular matrix degradation. It is asso..

Evaluation of genomic changes in ductal carcinoma in situ as potential biomarkers of recurrence risk

Dorothea Lesche, Hugo Saunders, Sakshi Mahale, Magnus Zenthoven, Siobhan Huges, Tanjina Kader, Niko Thio, Islam M Miligy, Jia-Min Pang, Andrew R Green, Emad A Rakha, Ian G Campbell, Stephen B Fox, Kylie Gorringe

Conference Proceedings  |  2020  |  Poster Session Abstracts

Combined Tumor Sequencing and Case-Control Analyses of RAD51C in Breast Cancer

Na Li, Simone McInerny, Magnus Zethoven, Dane Cheasley, Belle WX Lim, Simone M Rowley, Lisa Devereux, Norah Grewal, Somayeh Ahmadloo, David Byrne, Jue Er Amanda Lee, Jason Li, Stephen B Fox, Thomas John, Yoland Antill, Kylie L Gorringe, Paul A James, Ian G Campbell

Journal article  |  2019  |  JNCI: Journal of the National Cancer Institute

BACKGROUND: Loss-of-function variants in RAD51C are associated with familial ovarian cancer, but its role in hereditary breast can..

A combination of the immunohistochemical markers CK7 and SATB2 is highly sensitive and specific for distinguishing primary ovarian mucinous tumors from colorectal and appendiceal metastases

Nicola S Meagher, Linyuan Wang, Peter F Rambau, Maria P Intermaggio, David G Huntsman, Lynne R Wilkens, Mona A El-Bahrawy, Roberta B Ness, Kunle Odunsi, Helen Steed, Esther Herpel, Michael S Anglesio, Bonnie Zhang, Neil Lambie, Anthony J Swerdlow, Jan Lubinski, Robert A Vierkant, Ellen L Goode, Usha Menon, Aleksandra Toloczko-Grabarek, et al.

Journal article  |  2019  |  Modern Pathology

Primary ovarian mucinous tumors can be difficult to distinguish from metastatic gastrointestinal neoplasms by histology alone. The..

Collagen (XI) alpha-1 chain is an independent prognostic factor in breast ductal carcinoma in situ

Michael S Toss, Islam M Miligy, Kylie L Gorringe, Mohammed A Aleskandarany, Abdulbaqi Alkawaz, Karuna Mittal, Ritu Aneja, Ian O Ellis, Andrew R Green, Emad A Rakha

Journal article  |  2019  |  Modern Pathology

Collagen11A1 (COL11A1) is a fibrillary type collagen constituting a minor component of the extracellular matrix and plays role in ..

Geometric characteristics of collagen have independent prognostic significance in breast ductal carcinoma in situ: an image analysis study

Michael S Toss, Islam M Miligy, Kylie L Gorringe, Abdulbaqi AlKawaz, Karuna Mittal, Ritu Aneja, Ian O Ellis, Andrew R Green, Ioannis Roxanis, Emad A Rakha

Journal article  |  2019  |  Modern Pathology

Collagen plays a key role in normal and malignant tissue homeostasis. While the prognostic significance of collagen fiber remodeli..

The molecular origin and taxonomy of mucinous ovarian carcinoma

Dane Cheasley, Matthew J Wakefield, Georgina L Ryland, Prue E Allan, Kathryn Alsop, Kaushalya C Amarasinghe, Sumitra Ananda, Michael S Anglesio, George Au-Yeung, Maret Bohm, David Dl Bowtell, Alison Brand, Georgia Chenevix-Trench, Michael Christie, Yoke-Eng Chiew, Michael Churchman, Anna DeFazio, Renee Demeo, Rhiannon Dudley, Nicole Fairweather, et al.

Journal article  |  2019  |  NATURE COMMUNICATIONS

MOLECULAR DETERMINANTS OF CDK4 INHIBITOR ACTIVITY IN LOW-GRADE SEROUS OVARIAN CANCER

M Llaurado Fernandez, J Hoenisch, H Kim, A Dawson, N Lam, D Cheasley, K Gorrienge, N Abhimanyu, I Campbell, D Huntsman, G DiMattia, M Kobel, M Carey

Conference Proceedings  |  2019  |  E-Poster viewings

MUCINOUS OVARIAN CARCINOMA: THERAPEUTIC OPTIONS OLD AND NEW

K Gorringe, D Cheasley, M Wakefield, I Campbell, Y Antill, C Scott

Conference Proceedings  |  2019  |  Plenary sessions

Atypical ductal hyperplasia is a multipotent precursor of breast carcinoma

Tanjina Kader, Prue Hill, Magnus Zethoven, David L Goode, Kenneth Elder, Niko Thio, Maria Doyle, Timothy Semple, Wajiha Sufyan, David J Byrne, Jia-Min B Pang, Anand Murugasu, Islam M Miligy, Andrew R Green, Emad A Rakha, Stephen B Fox, G Bruce Mann, Ian G Campbell, Kylie L Gorringe

Journal article  |  2019  |  The Journal of Pathology

The prognostic significance of lysosomal protective protein (cathepsin A) in breast ductal carcinoma in situ

Michael S Toss, Islam M Miligy, Rita Haj-Ahmad, Kylie L Gorringe, Abdulbaqi AlKawaz, Karuna Mittal, Ian O Ellis, Andrew R Green, Emad A Rakha

Journal article  |  2019  |  Histopathology

Molecular comparison of interval and screen-detected breast cancers

Dane Cheasley, Na Li, Simone M Rowley, Kenneth Elder, G Bruce Mann, Sherene Loi, Peter Savas, David L Goode, Tanjina Kader, Magnus Zethoven, Tim Semple, Stephen B Fox, Jia-Min Pang, David Byrne, Lisa Devereux, Carolyn Nickson, Pietro Procopio, Grant Lee, Siobhan Hughes, Hugo Saunders, et al.

Journal article  |  2019  |  The Journal of Pathology

The clinical and biological significance of HER2 over-expression in breast ductal carcinoma in situ: a large study from a single institution

Islam M Miligy, Michael S Toss, Kylie L Gorringe, Andrew HS Lee, Ian O Ellis, Andrew R Green, Emad A Rakha

Journal article  |  2019  |  British Journal of Cancer

Legumain is an independent predictor for invasive recurrence in breast ductal carcinoma in situ

Michael S Toss, Islam M Miligy, Kylie L Gorringe, L McCaffrey, Abdulbaqi AlKawaz, Asima Abidi, Ian O Ellis, Andrew R Green, Emad A Rakha

Journal article  |  2019  |  Modern Pathology

When Is "Type I" Ovarian Cancer Not "Type I"? Indications of an Out-Dated Dichotomy

Carolina Salazar, Ian G Campbell, Kylie L Gorringe

Journal article  |  2018  |  FRONTIERS IN ONCOLOGY

Prolyl-4-hydroxylase A subunit 2 (P4HA2) expression is a predictor of poor outcome in breast ductal carcinoma in situ (DCIS)

Michael S Toss, Islam M Miligy, Kylie L Gorringe, Abdulbaqi Alkawaz, Hazem Khout, Ian O Ellis, Andrew R Green, Emad A Rakha

Journal article  |  2018  |  British Journal of Cancer

Thioredoxin-interacting protein is an independent risk stratifier for breast ductal carcinoma in situ

Islam M Miligy, Kylie L Gorringe, Michael S Toss, Abdulbaqi A Al-Kawaz, Peter Simpson, Maria Diez-Rodriguez, Christopher C Nolan, Ian O Ellis, Andrew R Green, Emad A Rakha

Journal article  |  2018  |  Modern Pathology

Mutations in RECQL are not associated with breast cancer risk in an Australian population

Na Li, Simone M Rowley, David L Goode, Kaushalya C Amarasinghe, Simone McInerny, Lisa Devereux, Michelle W Wong-Brown, Richard Lupat, Jue Er Amanda Lee, Siobhan Hughes, Ella R Thompson, Magnus Zethoven, Jason Li, Alison H Trainer, Kylie L Gorringe, Rodney J Scott, Paul A James, Ian G Campbell

Journal article  |  2018  |  Nature Genetics

Therapeutic opportunities in mucinous ovarian carcinoma

Kylie Gorringe, Ian Campbell, Clare Scott, Prue Allan, Dane Cheasley, Matthew Wakefield, Yoland Antill

Conference Proceedings  |  2018  |  INTERNATIONAL JOURNAL OF GYNECOLOGICAL CANCER

Clinical and biological roles of Kelch-like family member 7 in breast cancer: a marker of poor prognosis

Sasagu Kurozumi, Chitra Joseph, Sultan Sonbul, Kylie L Gorringe, Marian Pigera, Mohammed A Aleskandarany, Maria Diez-Rodriguez, Christopher C Nolan, Takaaki Fujii, Ken Shirabe, Hiroyuki Kuwano, Sarah Storr, Stewart G Martin, Ian O Ellis, Andrew R Green, Emad A Rakha

Journal article  |  2018  |  Breast Cancer Research and Treatment

Invasion in breast lesions: the role of the epithelial-stroma barrier

Emad A Rakha, Islam M Miligy, Kylie L Gorringe, Michael S Toss, Andrew R Green, Stephen B Fox, Fernando C Schmitt, Puay-Hoon Tan, Gary M Tse, Sunil Badve, Thomas Decker, Anne Vincent-Salomon, David J Dabbs, Maria P Foschini, Filipa Moreno, Wentao Yang, Felipe C Geyer, Jorge S Reis-Filho, Sarah E Pinder, Sunil R Lakhani, et al.

Journal article  |  2018  |  Histopathology

Atypical ductal hyperplasia: update on diagnosis, management, and molecular landscape

Tanjina Kader, Prue Hill, Emad A Rakha, Ian G Campbell, Kylie L Gorringe

Journal article  |  2018  |  Breast Cancer Research

Molecular analysis of PALB2-associated breast cancers

Jue Er Amanda Lee, Na Li, Simone M Rowley, Dane Cheasley, Magnus Zethoven, Simone McInerny, Kylie L Gorringe, Paul A James, Ian G Campbell

Journal article  |  2018  |  The Journal of Pathology

Functional and genomic characterisation of a xenograft model system for the study of metastasis in triple-negative breast cancer

Cameron N Johnstone, Andrew D Pattison, Kylie L Gorringe, Paul F Harrison, David R Powell, Peter Lock, David Baloyan, Matthias Ernst, Alastair G Stewart, Traude H Beilharz, Robin L Anderson

Journal article  |  2018  |  Disease Models & Mechanisms

Genomic analysis of cancers arising in breasts with different mammographic density

Kylie L Gorringe, Siobhan Hughes, Carolyn Nickson, Lisa Devereux, Vicki Pridmore, Simone M Rowley, David J Byrne, Dane Cheasley, Anne M Kavanagh, G Bruce Mann, Stephen B Fox, Ian G Campbell

Conference Proceedings  |  2018  |  CANCER RESEARCH

Evaluating the breast cancer predisposition role of rare variants in genes associated with low-penetrance breast cancer risk SNPs

Na Li, Simone M Rowley, Ella R Thompson, Simone McInerny, Lisa Devereux, Kaushalya C Amarasinghe, Magnus Zethoven, Richard Lupat, David Goode, Jason Li, Alison H Trainer, Kylie L Gorringe, Paul A James, Ian G Campbell

Journal article  |  2018  |  BREAST CANCER RESEARCH

Ductal Carcinoma In Situ Biology, Biomarkers, and Diagnosis

Kylie L Gorringe, Stephen B Fox

Journal article  |  2017  |  Frontiers in Oncology

LRH-1 expression patterns in breast cancer tissues are associated with tumour aggressiveness

Jia-Min B Pang, Ramyar Molania, Ashwini Chand, Kevin Knower, Elena A Takano, David J Byrne, Thomas Mikeska, Ewan KA Millar, Cheok Soon Lee, Sandra A O'Toole, Colin Clyne, Kylie L Gorringe, Alexander Dobrovic, Stephen B Fox

Journal article  |  2017  |  Oncotarget

BRCA2 carriers with male breast cancer show elevated tumour methylation

Siddhartha Deb, Kylie L Gorringe, Jia-Min B Pang, David J Byrne, Elena A Takano, Alexander Dobrovic, Stephen B Fox

Journal article  |  2017  |  BMC Cancer

Relationship of the Breast Ductal Carcinoma In Situ Immune Microenvironment with Clinicopathological and Genetic Features

Shona Hendry, Jia-Min B Pang, David J Byrne, Sunil R Lakhani, Margaret C Cummings, Ian G Campbell, G Bruce Mann, Kylie L Gorringe, Stephen B Fox

Journal article  |  2017  |  Clinical Cancer Research

Phenotypic characterisation of breast cancer: the role of CDC42

Eleni Chrysanthou, Kylie L Gorringe, Chitra Joseph, Madeleine Craze, Christopher C Nolan, Maria Diez-Rodriguez, Andrew R Green, Emad A Rakha, Ian O Ellis, Abhik Mukherjee

Journal article  |  2017  |  Breast Cancer Research and Treatment

Breast ductal carcinoma in situ carry mutational driver events representative of invasive breast cancer

Jia-Min B Pang, Peter Savas, Andrew P Fellowes, Gisela Mir Arnau, Tanjina Kader, Ravikiran Vedururu, Chelsee Hewitt, Elena A Takano, David J Byrne, David YH hoong, Ewan KA Millar, C Soon Lee, Sandra A O'Toole, Sunil R Lakhani, Margaret C Cummings, G Bruce Mann, Ian G Campbell, Alexander Dobrovic, Sherene Loi, Kylie L Gorringe, et al.

Journal article  |  2017  |  Modern Pathology

Chemokine (C-C motif) receptor 7 (CCR7) associates with the tumour immune microenvironment but not progression in invasive breast carcinoma

Sultan N Sonbul, Kylie L Gorringe, Mohammed A Aleskandarany, Abhik Mukherjee, Andrew R Green, Ian O Ellis, Emad A Rakha

Journal article  |  2017  |  The Journal of Pathology: Clinical Research

Copy number analysis by low coverage whole genome sequencing using ultra low-input DNA from formalin-fixed paraffin embedded tumor tissue

Tanjina Kader, David L Goode, Stephen Q Wong, Jacquie Connaughton, Simone M Rowley, Lisa Devereux, David Byrne, Stephen B Fox, Gisela Mir Arnau, Richard W Tothill, Ian G Campbell, Kylie L Gorringe

Journal article  |  2016  |  GENOME MEDICINE

Reevaluation of RINT1 as a breast cancer predisposition gene

Na Li, Ella R Thompson, Simone M Rowley, Simone McInerny, Lisa Devereux, David Goode, Michelle W Wong-Brown, Rodney J Scott, Alison H Trainer, Kylie L Gorringe, Paul A James, Ian G Campbell

Journal article  |  2016  |  Breast Cancer Research and Treatment

Reply to the Baader-Meinhof phenomenon in ductal carcinoma in situ of the breast

Jia-Min B Pang, Kylie L Gorringe, Stephen B Fox

Journal article  |  2016  |  Histopathology

Genomic Analysis

SM Hunter, AE McCart Reed, IG Campbell, KL Gorringe

Book Chapter  |  2016

The aim of the book is to discuss the application of molecular pathology in cancer research, and its contribution in the classific..

Ductal carcinoma in situ - update on risk assessment and management

Jia-Min B Pang, Kylie L Gorringe, Stephen B Fox

Journal article  |  2016  |  Histopathology

Molecular profiling of low grade serous ovarian tumours identifies novel candidate driver genes

SM Hunter, MS Anglesio, GL Ryland, R Sharma, YE Chiew, SM Rowley, MA Doyle, J Li, CB Gilks, P Moss, PE Allan, AN Stephens, DG Huntsman, A deFazio, DD Bowtell, G Australian Ovarian Cancer Study, KL Gorringe, IG Campbell

Journal article  |  2015  |  Oncotarget

Low grade serous ovarian tumours are a rare and under-characterised histological subtype of epithelial ovarian tumours, with littl..

Reevaluation of the BRCA2 truncating allele c.9976A > T (p.Lys3326Ter) in a familial breast cancer context

Ella R Thompson, Kylie L Gorringe, Simone M Rowley, Na Li, Simone McInerny, Michelle W Wong-Brown, Lisa Devereux, Jason Li, Alison H Trainer, Gillian Mitchell, Rodney J Scott, Paul A James, Ian G Campbell

Journal article  |  2015  |  Sci Rep

Copy number analysis of ductal carcinoma in situ with and without recurrence

Kylie L Gorringe, Sally M Hunter, Jia-Min Pang, Ken Opeskin, Prue Hill, Simone M Rowley, David YH Choong, Ella R Thompson, Alexander Dobrovic, Stephen B Fox, G Bruce Mann, Ian G Campbell

Journal article  |  2015  |  Modern Pathology

Prevalence of PALB2 mutations in Australian familial breast cancer cases and controls

Ella R Thompson, Kylie L Gorringe, Simone M Rowley, Michelle W Wong-Brown, Simone McInerny, Na Li, Alison H Trainer, Lisa Devereux, Maria A Doyle, Jason Li, Richard Lupat, Martin B Delatycki, Gillian Mitchell, Paul A James, Rodney J Scott, Ian G Campbell

Journal article  |  2015  |  Breast Cancer Res

Mutational landscape of mucinous ovarian carcinoma and its neoplastic precursors

Georgina L Ryland, Sally M Hunter, Maria A Doyle, Franco Caramia, Jason Li, Simone M Rowley, Michael Christie, Prue E Allan, Andrew N Stephens, David DL Bowtell, Ian G Campbell, Kylie L Gorringe

Journal article  |  2015  |  GENOME MEDICINE

Loss of heterozygosity: what is it good for?

Georgina L Ryland, Maria A Doyle, David Goode, Samantha E Boyle, David YH Choong, Simone M Rowley, Jason Li, David DL Bowtell, Richard W Tothill, Ian G Campbell, Kylie L Gorringe

Journal article  |  2015  |  BMC Med Genomics

Appraisal of the technologies and review of the genomic landscape of ductal carcinoma in situ of the breast

Jia-Min B Pang, Kylie L Gorringe, Stephen Q Wong, Alexander Dobrovic, Ian G Campbell, Stephen B Fox

Journal article  |  2015  |  Breast Cancer Research

Enhanced GAB2 Expression Is Associated with Improved Survival in High-Grade Serous Ovarian Cancer and Sensitivity to PI3K Inhibition

Sally J Davis, Karen E Sheppard, Michael S Anglesio, Joshy George, Nadia Traficante, Sian Fereday, Maria P Intermaggio, Usha Menon, Aleksandra Gentry-Maharaj, Jan Lubinski, Jacek Gronwald, Celeste Leigh Pearce, Malcolm C Pike, Anna Wu, Stefan Kommoss, Jacobus Pfisterer, Andreas du Bois, Felix Hilpert, Susan J Ramus, David DL Bowtell, et al.

Journal article  |  2015  |  MOLECULAR CANCER THERAPEUTICS

Genomic Aberrations of BRCA1-Mutated Fallopian Tube Carcinomas

Sally M Hunter, Georgina L Ryland, Phillip Moss, Kylie L Gorringe, Ian G Campbell

Journal article  |  2014  |  The American Journal of Pathology

Functional Analysis of Genes in Regions Commonly Amplified in High-Grade Serous and Endometrioid Ovarian Cancer

Sally J Davis, Karen E Sheppard, Richard B Pearson, Ian G Campbell, Kylie L Gorringe, Kaylene J Simpson

Journal article  |  2013  |  CLINICAL CANCER RESEARCH

RNF43 is a tumour suppressor gene mutated in mucinous tumours of the ovary

Georgina L Ryland, Sally M Hunter, Maria A Doyle, Simone M Rowley, Michael Christie, Prue E Allan, David DL Bowtell, Kylie L Gorringe, Ian G Campbell

Journal article  |  2013  |  Journal of Pathology

Identifying Associations Between Genomic Alterations in Tumors

Joshy George, Kylie L Gorringe, Gordon K Smyth, David DL Bowtell

Book Chapter  |  2013  |  Methods in Molecular Biology

Pre-Invasive Ovarian Mucinous Tumors Are Characterized by CDKN2A and RAS Pathway Aberrations

Sally M Hunter, Kylie L Gorringe, Michael Christie, Simone M Rowley, David D Bowtell, Ian G Campbell

Journal article  |  2012  |  CLINICAL CANCER RESEARCH

Analysis of KLLN as a high-penetrance breast cancer predisposition gene

Ella R Thompson, Kylie L Gorringe, David YH Choong, Diana M Eccles, Gillian Mitchell, Ian G Campbell

Journal article  |  2012  |  BREAST CANCER RESEARCH AND TREATMENT

Identification of copy number alterations associated with the progression of DCIS to invasive ductal carcinoma

Clint E Johnson, Kylie L Gorringe, Ella R Thompson, Ken Opeskin, Samantha E Boyle, Yuker Wang, Prue Hill, G Bruce Mann, Ian G Campbell

Journal article  |  2012  |  Breast Cancer Research and Treatment

CONTRA: copy number analysis for targeted resequencing

Jason Li, Richard Lupat, Kaushalya C Amarasinghe, Ella R Thompson, Maria A Doyle, Georgina L Ryland, Richard W Tothill, Saman K Halgamuge, Ian G Campbell, Kylie L Gorringe

Journal article  |  2012  |  BIOINFORMATICS

MicroRNA Genes and Their Target 3 '-Untranslated Regions Are Infrequently Somatically Mutated in Ovarian Cancers

Georgina L Ryland, Jennifer L Bearfoot, Maria A Doyle, Samantha E Boyle, David YH Choong, Simone M Rowley, Richard W Tothill, Kylie L Gorringe, Ian G Campbell

Journal article  |  2012  |  PLoS One

An activating Pik3ca mutation coupled with Pten loss is sufficient to initiate ovarian tumorigenesis in mice

Kathryn M Kinross, Karen G Montgomery, Margarete Kleinschmidt, Paul Waring, Ivan Ivetac, Anjali Tikoo, Mirette Saad, Lauren Hare, Vincent Roh, Theo Mantamadiotis, Karen E Sheppard, Georgina L Ryland, Ian G Campbell, Kylie L Gorringe, James G Christensen, Carleen Cullinane, Rodney J Hicks, Richard B Pearson, Ricky W Johnstone, Grant A McArthur, et al.

Journal article  |  2012  |  JOURNAL OF CLINICAL INVESTIGATION

Copy Number Aberrations in Benign Serous Ovarian Tumors: A Case for Reclassification?

Sally M Hunter, Michael S Anglesio, Raghwa Sharma, C Blake Gilks, Nataliya Melnyk, Yoke-Eng Chiew, Anna deFazio, Teri A Longacre, David G Huntsman, Kylie L Gorringe, Ian G Campbell

Journal article  |  2011  |  Clinical Cancer Research

Analysis of the Mitogen-activated protein kinase kinase 4 (MAP2K4) tumor suppressor gene in ovarian cancer

Sally J Davis, David YH Choong, Manasa Ramakrishna, Georgina L Ryland, Ian G Campbell, Kylie L Gorringe

Journal article  |  2011  |  BMC Cancer

IL6-STAT3-HIF Signaling and Therapeutic Response to the Angiogenesis Inhibitor Sunitinib in Ovarian Clear Cell Cancer

Michael S Anglesio, Joshy George, Hagen Kulbe, Michael Friedlander, Danny Rischin, Charlotte Lemech, Jeremy Power, Jermaine Coward, Prue A Cowin, Colin M House, Probir Chakravarty, Kylie L Gorringe, Ian G Campbell, Aikou Okamoto, Michael J Birrer, David G Huntsman, Anna de Fazio, Steve E Kalloger, Frances Balkwill, C Blake Gilks, et al.

Journal article  |  2011  |  Clinical Cancer Research

Amplicon-Dependent CCNE1 Expression Is Critical for Clonogenic Survival after Cisplatin Treatment and Is Correlated with 20q11 Gain in Ovarian Cancer

Dariush Etemadmoghadam, Joshy George, Prue A Cowin, Carleen Cullinane, Maya Kansara, Kylie L Gorringe, Gordon K Smyth, David DL Bowtell

Journal article  |  2010  |  PLoS One

Copy Number Analysis Identifies Novel Interactions Between Genomic Loci in Ovarian Cancer

Kylie L Gorringe, Joshy George, Michael S Anglesio, Manasa Ramakrishna, Dariush Etemadmoghadam, Prue Cowin, Anita Sridhar, Louise H Williams, Samantha E Boyle, Nozomu Yanaihara, Aikou Okamoto, Mitsuyoshi Urashima, Gordon K Smyth, Ian G Campbell, David DL Bowtell

Journal article  |  2010  |  PLoS One

Exploiting sequence similarity to validate the sensitivity of SNP arrays in detecting fine-scaled copy number variations

Gerard Wong, Christopher Leckie, Kylie L Gorringe, Izhak Haviv, Ian G Campbell, Adam Kowalczyk

Journal article  |  2010  |  Bioinformatics

Identification of Candidate Growth Promoting Genes in Ovarian Cancer through Integrated Copy Number and Expression Analysis

Manasa Ramakrishna, Louise H Williams, Samantha E Boyle, Jennifer L Bearfoot, Anita Sridhar, Terence P Speed, Kylie L Gorringe, Ian G Campbell

Journal article  |  2010  |  PLOS ONE

Are There Any More Ovarian Tumor Suppressor Genes? A New Perspective Using Ultra High-Resolution Copy Number and Loss of Heterozygosity Analysis

Kylie L Gorringe, Manasa Ramakrishna, Louise H Williams, Anita Sridhar, Samantha E Boyle, Jennifer L Bearfoot, Jason Li, Michael S Anglesio, Ian G Campbell

Journal article  |  2009  |  Genes, Chromosomes & Cancer

Large-scale genomic analysis of ovarian carcinomas

Kylie L Gorringe, Ian G Campbell

Journal article  |  2009  |  Molecular Oncology

Genetic Analysis of Cancer-implicated MicroRNA in Ovarian Cancer

Jennifer L Bearfoot, David YH Choong, Kylie L Gorringe, Ian G Campbell

Journal article  |  2008  |  Clinical Cancer Research

Mutation and Methylation Analysis of the Chromodomain-Helicase-DNA Binding 5 Gene in Ovarian Cancer

Kylie L Gorringe, David Choong, Louise H Williams, Manasa Ramakrishna, Anita Sridhar, Wen Qiu, Jennifer L Bearfoot, Ian G Campbell

Journal article  |  2008  |  Neoplasia

High-resolution copy number arrays in cancer and the problem of normal genome copy number variation

Kylie L Gorringe, Ian G Campbell

Journal article  |  2008  |  Genes, Chromosomes & Cancer

Breast cancer risk and the BRCA1 interacting protein CTIP

Kylie L Gorringe, David YH Choong, Geoffrey J Lindeman, Jane E Visvader, Ian G Campbell

Journal article  |  2008  |  Breast Cancer Research and Treatment

BARD1 variants are not associated with breast cancer risk in Australian familial breast cancer

Kylie L Gorringe, David YH Choong, Jane E Visvader, Geoffrey J Lindeman, Ian G Campbell

Journal article  |  2008  |  Breast Cancer Research and Treatment

No evidence of clonal somatic genetic alterations in cancer-associated fibroblasts from human breast and ovarian carcinomas

Wen Qiu, Min Hu, Anita Sridhar, Ken Opeskin, Stephen Fox, Michail Shipitsin, Melanie Trivett, Ella R Thompson, Manasa Ramakrishna, Kylie L Gorringe, Kornelia Polyak, Izhak Haviv, Ian G Campbell

Journal article  |  2008  |  Nature Genetics

A rational approach to cancer therapy.

Kylie L Gorringe, Ian G Campbell

Journal article  |  2008  |  Genome Biology

High-resolution single nucleotide polymorphism array analysis of epithelial ovarian cancer reveals numerous microdeletions and amplifications

Kylie L Gorringe, Sharoni Jacobs, Ella R Thompson, Anita Sridhar, Wen Qiu, David YH Choong, Ian G Campbell

Journal article  |  2007  |  Clinical Cancer Research

Gender Differences in Publication Output: Towards an Unbiased Metric of Research Performance

Matthew RE Symonds, Neil J Gemmell, Tamsin L Braisher, Kylie L Gorringe, Mark A Elgar

Journal article  |  2006  |  PLOS ONE

A molecular model for sporadic human aneuploidy

WD Warren, KL Gorringe

Journal article  |  2006  |  Trends in Genetics

Evidence that both genetic instability and selection contribute to the accumulation of chromosome alterations in cancer

KL Gorringe, SF Chin, P Pharoah, JM Staines, C Oliveira, PAW Edwards, C Caldas

Journal article  |  2005  |  Carcinogenesis

Novel regions of chromosomal amplification at 6p21, 5p13, and 12q14 in gastric cancer identified by array comparative genomic hybridization

KL Gorringe, A Boussioutas, DDL Bowtell

Journal article  |  2005  |  Genes, Chromosomes & Cancer

Distinctive patterns of gene expression in premalignant gastric mucosa and gastric cancer

A Boussioutas, H Li, J Liu, P Waring, S Lade, AJ Holloway, D Taupin, K Gorringe, I Haviv, PV Desmond, DDL Bowtell

Journal article  |  2003  |  Cancer Research

Molecular cytogenetic analysis of breast cancer cell lines

JM Davidson, KL Gorringe, SF Chin, B Orsetti, C Besret, C Courtay-Cahen, I Roberts, C Theillet, C Caldas, PAW Edwards

Journal article  |  2000  |  British Journal of Cancer

Identification of germ-line E-cadherin mutations in gastric cancer families of European origin

SA Gayther, KL Gorringe, SJ Ramus, D Huntsman, F Roviello, N Grehan, JC Machado, E Pinto, R Seruca, K Halling, P MacLeod, SM Powell, CE Jackson, BAJ Ponder, C Caldas

Journal article  |  1998  |  Cancer Research

Loss of Heterozygosity

Kylie L Gorringe

Journal article  |  eLS