Ben Howden

Sample pooling on the Cepheid Xpert® Xpress SARS-CoV-2 assay.

Maryza Graham, Eloise Williams, Nicole Isles, Eka Buadromo, Tebuka Toatu, Julian Druce, Mike Catton, Chantel Lin, Benjamin P Howden, Deborah A Williamson

Journal article  |  2021  |  Diagnostic Microbiology and Infectious Disease

The COVID-19 pandemic has placed unprecedented global demand on laboratory supplies required for testing. Sample pooling has been ..

Comprehensive Genomic Investigation of Adaptive Mutations Driving the Low-Level Oxacillin Resistance Phenotype in Staphylococcus aureus.

Stefano G Giulieri, Romain Guérillot, Jason C Kwong, Ian R Monk, Ashleigh S Hayes, Diane Daniel, Sarah Baines, Norelle L Sherry, Natasha E Holmes, Peter Ward, Wei Gao, Torsten Seemann, Timothy P Stinear, Benjamin P Howden

Journal article  |  2020  |  mBio

Antistaphylococcal penicillins such as oxacillin are the key antibiotics in the treatment of invasive methicillin-susceptible Stap..

Implementation and evaluation of a novel real-time multiplex assay for SARS-CoV-2: in-field learnings from a clinical microbiology laboratory

Eloise Williams, Katherine Bond, Brian Chong, Dawn Giltrap, Malcolm Eaton, Peter Kyriakou, Peter Calvert, Bowen Zhang, Mahendra Siwan, Benjamin Howden, Julian Druce, Mike Catton, Deborah A Williamson

Journal article  |  2020  |  Pathology

The unprecedented scale of testing required to effectively control the coronavirus disease (COVID-19) pandemic has necessitated ur..

Prolonged Outbreak of Multidrug-Resistant Shigella sonnei Harboring bla(CTX-M-27) in Victoria, Australia

Danielle J Ingle, Patiyan Andersson, Mary Valcanis, Jessica Barnden, Anders Goncalves da Silva, Kristy A Horan, Torsten Seemann, Marion Easton, Deborah A Williamson, Norelle L Sherry, Benjamin P Howden

Journal article  |  2020  |  Antimicrobial Agents and Chemotherapy

In Australia, cases of shigellosis usually occur in returned travelers from regions of shigellosis endemicity or in men who have s..

Structure-Activity Relationships of Daptomycin Lipopeptides.

John A Karas, Glen P Carter, Benjamin P Howden, Adrianna M Turner, Olivia KA Paulin, James D Swarbrick, Mark A Baker, Jian Li, Tony Velkov

Journal article  |  2020  |  Journal of Medicinal Chemistry

Daptomycin is a calcium-dependent cyclic lipodepsipeptide derived from the soil saprotroph Streptomyces roseosporus, and its antib..

An open-label, parallel-group, randomised controlled trial of antiseptic mouthwash versus antibiotics for oropharyngeal gonorrhoea treatment (OMEGA2)

Eric PF Chow, Kate Maddaford, Jane S Hocking, Catriona S Bradshaw, Rebecca Wigan, Marcus Y Chen, Benjamin P Howden, Deborah A Williamson, Christopher K Fairley

Journal article  |  2020  |  Scientific Reports

New treatments for oropharyngeal gonorrhoea are required to address rising antimicrobial resistance. We aimed to examine the effic..

Complete microbial genomes for public health in Australia and the Southwest Pacific

Sarah L Baines, Anders Goncalves da Silva, Glen P Carter, Amy Jennison, Irani Rathnayake, Rikki M Graham, Vitali Sintchenko, Qinning Wang, Rebecca J Rockett, Verlaine J Timms, Elena Martinez, Susan Ballard, Takehiro Tomita, Nicole Isles, Kristy A Horan, William Pitchers, Timothy P Stinear, Deborah A Williamson, Benjamin P Howden, Torsten Seemann

Journal article  |  2020  |  Microbial Genomics

Complete genomes of microbial pathogens are essential for the phylogenomic analyses that increasingly underpin core public health ..

Case Report: Confirmation by Metagenomic Sequencing of Visceral Leishmaniasis in an Immunosuppressed Returned Traveler

Eloise Williams, Nicole S Isles, Torsten Seemann, Trevor Kilpatrick, Andrew Grigg, Marcel Leroi, Benjamin P Howden, Jason C Kwong

Journal article  |  2020  |  American Journal of Tropical Medicine and Hygiene

There has been increased interest in using metagenomic next-generation sequencing as an unbiased approach for diagnosing infectiou..

Serological tests for COVID--19 Serological assays for SARS-CoV-2 present challenges and opportunities

Katherine Bond, Eloise Williams, Benjamin P Howden, Deborah A Williamson

Journal article  |  2020  |  Medical Journal of Australia

Evaluation of Serological Tests for SARS-CoV-2: Implications for Serology Testing in a Low-Prevalence Setting

Katherine Bond, Suellen Nicholson, Seok Ming Lim, Theo Karapanagiotidis, Eloise Williams, Douglas Johnson, Tuyet Hoang, Cheryll Sia, Damian Purcell, Francesca Mordant, Sharon R Lewin, Mike Catton, Kanta Subbarao, Benjamin P Howden, Deborah A Williamson

Journal article  |  2020  |  Journal of Infectious Diseases

BACKGROUND: Robust serological assays are essential for long-term control of the COVID-19 pandemic. Many recently released point-o..