Jaime Foong

Enteric neuroimmune interactions coordinate intestinal responses in health and disease

Haozhe Wang, Jaime PP Foong, Nicola L Harris, Joel C Bornstein

Journal article  |  2021  |  MUCOSAL IMMUNOLOGY

The enteric nervous system (ENS) of the gastrointestinal (GI) tract interacts with the local immune system bidirectionally. Recent..

83 NEONATAL ANTIBIOTICS HAVE LONG TERM SEX-DEPENDENT EFFECTS ON THE ENTERIC NERVOUS SYSTEM AND METABOLISM

Sabrina S Poon, Lin Y Hung, Qinglong Wu, Pavitha Parathan, Anthony Haag, Ruth Ann Luna, Matthew J Watt, Tor C Savidge, Joel C Bornstein, Jaime Pei Pei Foong

Journal article  |  2021  |  Gastroenterology

Early life interaction between the microbiota and the enteric nervous system

Jaime PP Foong, Lin Y Hung, Sabrina Poon, Tor C Savidge, Joel C Bornstein

Journal article  |  2020  |  AMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGY

Recent studies on humans and their key experimental model, the mouse, have begun to uncover the importance of gastrointestinal (GI..

Early-life malnutrition causes gastrointestinal dysmotility that is sexually dimorphic

Krishnakant G Soni, Peace N Dike, Ji Ho Suh, Tripti Halder, Price T Edwards, Jaime PP Foong, Margaret E Conner, Geoffrey A Preidis

Journal article  |  2020  |  NEUROGASTROENTEROLOGY AND MOTILITY

BACKGROUND: Slow gastrointestinal (GI) transit occurs in moderate-to-severe malnutrition. Mechanisms underlying malnutrition-assoc..

Antibiotic exposure postweaning disrupts the neurochemistry and function of enteric neurons mediating colonic motor activity

Lin Y Hung, Pavitha Parathan, Prapaporn Boonma, Qinglong Wu, Yi Wang, Anthony Haag, Ruth Ann Luna, Joel C Bornstein, Tor C Savidge, Jaime PP Foong

Journal article  |  2020  |  AMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGY

The period during and immediately after weaning is an important developmental window when marked shifts in gut microbiota can regu..

The enteric nervous system undergoes significant chemical and synaptic maturation during adolescence in mice

Pavitha Parathan, Yi Wang, Anita JL Leembruggen, Joel C Bornstein, Jaime PP Foong

Journal article  |  2020  |  DEVELOPMENTAL BIOLOGY

Adolescence is a critical period of development. It is very likely that there is significant maturation of the enteric nervous sys..

alpha-Synuclein Regulates Development and Function of Cholinergic Enteric Neurons in the Mouse Colon

M Swaminathan, C Fung, D Finkelstein, JC Bornstein, JPP Foong

Journal article  |  2019  |  NEUROSCIENCE

Alpha-Synuclein (α-Syn) is expressed in the central nervous system and the nervous system of the gut (enteric nervous system, ENS)..

Endogenous Glutamate Excites Myenteric Calbindin Neurons by Activating Group I Metabotropic Glutamate Receptors in the Mouse Colon

Mathusi Swaminathan, Elisa L Hill-Yardin, Joel C Bornstein, Jaime PP Foong

Journal article  |  2019  |  FRONTIERS IN NEUROSCIENCE

Glutamate is a classic excitatory neurotransmitter in the central nervous system (CNS), but despite several studies reporting the ..

Neonatal Antibiotics Disrupt Motility and Enteric Neural Circuits in Mouse Colon

Lin Y Hung, Prapaporn Boonma, Petra Unterweger, Pavitha Parathan, Anthony Haag, Ruth Ann Luna, Joel C Bornstein, Tor C Savidge, Jaime PP Foong

Journal article  |  2019  |  CELLULAR AND MOLECULAR GASTROENTEROLOGY AND HEPATOLOGY

Exposure to the antibiotic, vancomycin perturbs gut microbiota, mucosal serotonin and enteric neuron development of the early postnatal mouse colon

JPP Foong, LY Hung, P Unterweger, P Parathan, B Prapaporn, A Haag, RA Luna, JC Bornstein, TC Savidge

Conference Proceedings  |  2018  |  NEUROGASTROENTEROLOGY AND MOTILITY