Jaime Foong

Early life interaction between the microbiota and the enteric nervous system

Jaime PP Foong, Lin Y Hung, Sabrina Poon, Tor C Savidge, Joel C Bornstein

Journal article  |  2020  |  American Journal of Physiology-Gastrointestinal and Liver Physiology

Recent studies on humans and their key experimental model, the mouse, have begun to uncover the importance of gastrointestinal (GI..

Early-life malnutrition causes gastrointestinal dysmotility that is sexually dimorphic

Krishnakant G Soni, Peace N Dike, Ji Ho Suh, Tripti Halder, Price T Edwards, Jaime PP Foong, Margaret E Conner, Geoffrey A Preidis

Journal article  |  2020  |  Neurogastroenterology & Motility

Antibiotic exposure postweaning disrupts the neurochemistry and function of enteric neurons mediating colonic motor activity.

Lin Y Hung, Pavitha Parathan, Prapaporn Boonma, Qinglong Wu, Yi Wang, Anthony Haag, Ruth Ann Luna, Joel C Bornstein, Tor C Savidge, Jaime PP Foong

Journal article  |  2020  |  American Journal of Physiology-Gastrointestinal and Liver Physiology

The period during and immediately after weaning is an important developmental window when marked shifts in gut microbiota can regu..

The enteric nervous system undergoes significant chemical and synaptic maturation during adolescence in mice

Pavitha Parathan, Yi Wang, Anita JL Leembruggen, Joel C Bornstein, Jaime PP Foong

Journal article  |  2020  |  Developmental Biology

Adolescence is a critical period of development. It is very likely that there is significant maturation of the enteric nervous sys..

alpha-Synuclein Regulates Development and Function of Cholinergic Enteric Neurons in the Mouse Colon

M Swaminathan, C Fung, D Finkelstein, JC Bornstein, JPP Foong

Journal article  |  2019  |  Neuroscience

Alpha-Synuclein (α-Syn) is expressed in the central nervous system and the nervous system of the gut (enteric nervous system, ENS)..

Endogenous Glutamate Excites Myenteric Calbindin Neurons by Activating Group I Metabotropic Glutamate Receptors in the Mouse Colon

Mathusi Swaminathan, Elisa L Hill-Yardin, Joel C Bornstein, Jaime PP Foong

Journal article  |  2019  |  Frontiers in Neuroscience

Neonatal Antibiotics Disrupt Motility and Enteric Neural Circuits in Mouse Colon

Lin Y Hung, Prapaporn Boonma, Petra Unterweger, Pavitha Parathan, Anthony Haag, Ruth Ann Luna, Joel C Bornstein, Tor C Savidge, Jaime PP Foong

Journal article  |  2019  |  Cellular and Molecular Gastroenterology and Hepatology

Exposure to the antibiotic, vancomycin perturbs gut microbiota, mucosal serotonin and enteric neuron development of the early postnatal mouse colon

JPP Foong, LY Hung, P Unterweger, P Parathan, B Prapaporn, A Haag, RA Luna, JC Bornstein, TC Savidge

Conference Proceedings  |  2018  |  NEUROGASTROENTEROLOGY AND MOTILITY

Perturbation of gut microbiota with the antibiotic, vancomycin, between weaning and adulthood affects enteric neuronal excitability and motility in the mouse colon

L-Y Hung, P Parathan, P Boonma, A Haag, RA Luna, JC Bornstein, T Savidge, JPP Foong

Conference Proceedings  |  2018  |  NEUROGASTROENTEROLOGY AND MOTILITY

PERTURBING THE GUT MICROBIOTA IN MICE WITH THE ANTIBIOTIC, VANCOMYCIN, REDUCES SEROTONIN PRODUCTION AND ALTERS ENTERIC NERVOUS SYSTEM DEVELOPMENT IN EARLY POSTNATAL COLON

Lin Y Hung, Petra Unterweger, Pavitha Parathan, Prapoporn Boonma, Anthony Haag, Ruth Ann Luna, Joel C Bornstein, Tor C Savidge, Jaime Pei Pei Foong

Conference Proceedings  |  2018  |  GASTROENTEROLOGY