Dorothy Machalek

The Natural History of Anal High-grade Squamous Intraepithelial Lesions in Gay and Bisexual Men.

I Mary Poynten, Fengyi Jin, Jennifer M Roberts, David J Templeton, Carmella Law, Alyssa M Cornall, Monica Molano, Dorothy A Machalek, Andrew Carr, Annabelle Farnsworth, Sepehr Tabrizi, Samuel Phillips, Christopher K Fairley, Suzanne M Garland, Richard J Hillman, Andrew E Grulich

Journal article  |  2020  |  Clinical Infectious Diseases

BACKGROUND: Gay and bisexual men (GBM) are disproportionately affected by anal cancer. Prevention is hindered by incomplete unders..

Adenomyosis is Associated with Patient-reported Recurrent Endometriosis.

Peter AW Rogers, Dorothy A Machalek, Jane Girline, Jacqueline Donoghue, Uri Dior, Martin Healey, Sarah J Holdsworth-Carson

Conference Proceedings  |  2020  |  REPRODUCTIVE SCIENCES

Performance of the ResistancePlus MG diagnostic test for Mycoplasma genitalium using samples collected with Hologic Aptima Specimen Collection kits

Gerald L Murray, Jennifer Danielewski, Catriona S Bradshaw, Deborah A Williamson, Joshua Birnie, Jenny P Su, Vesna De Petra, Lit Y Tan, Rachel Wee, Dorothy A Machalek, Tim RH Read, Suzanne M Garland

Journal article  |  2020  |  Journal of Medical Microbiology

Introduction. Mycoplasma genitalium is a sexually transmitted organism with high levels of resistance to the recommended first..

The natural history of anal high grade squamous intraepithelial lesions in HIV positive and HIV negative gay and bisexual men

DJ Templeton, IM Poynten, F Jin, JM Roberts, CLH Law, AM Cornall, M Molano, DA Machalek, A Carr, A Farnsworth, S Tabrizi, S Phillips, CK Fairley, SM Garland, RJ Hillman, AE Grulich

Conference Proceedings  |  2019  |  HIV MEDICINE

Prevalence of human papillomavirus in teenage heterosexual males following the implementation of female and male school-based vaccination in Australia: 2014-2017

Eric PF Chow, Sepehr N Tabrizi, Christopher K Fairley, Rebecca Wigan, Dorothy A Machalek, David G Regan, Jane S Hocking, Suzanne M Garland, Alyssa M Cornall, Steph Atchison, Catriona S Bradshaw, Anna McNulty, Louise Owen, Lewis Marshall, Darren B Russell, John M Kaldor, Marcus Y Chen

Journal article  |  2019  |  Vaccine

BACKGROUND: Australia introduced a school-based human papillomavirus (HPV) vaccination program for females aged 12-13 years in 200..

Analysis of Infection Loads in Mycoplasma genitalium Clinical Specimens by Use of a Commercial Diagnostic Test

Gerald L Murray, Jennifer Danielewski, Kaveesha Bodiyabadu, Dorothy A Machalek, Catriona S Bradshaw, Anna-Maria Costa, Josh Birnie, Suzanne M Garland

Journal article  |  2019  |  Journal of Clinical Microbiology

Mycoplasma genitalium is a common sexually transmitted infection with a propensity to acquire resistance to commonly used antimicr..

Population-level impact and herd effects following the introduction of human papillomavirus vaccination programmes: updated systematic review and meta-analysis

Melanie Drolet, Elodie Benard, Norma Perez, Marc Brisson, Marie-Claude Boily, Hammad Ali, Vincenzo Baldo, Paul Brassard, Julia ML Brotherton, Denton Callander, Marta Checchi, Eric PF Chow, Silvia Cocchio, Tina Dalianis, Shelley L Deeks, Christian Dehlendorff, Basil Donovan, Christopher K Fairley, Elaine W Flagg, Julia W Gargano, et al.

Journal article  |  2019  |  The Lancet

BACKGROUND: More than 10 years have elapsed since human papillomavirus (HPV) vaccination was implemented. We did a systematic revi..

Routine cervical screening by primary HPV testing: early findings in the renewed National Cervical Screening Program

Dorothy A Machalek, Jennifer M Roberts, Suzanne M Garland, Julia Thurloe, Adele Richards, Ian Chambers, Terri Sivertsen, Annabelle Farnsworth

Journal article  |  2019  |  Medical Journal of Australia

OBJECTIVES: To report human papillomavirus (HPV) testing patterns and rates of oncogenic HPV-positivity for specimens submitted du..

The impact of sample storage on molecular-based detection of Mycoplasma genitalium

GL Murray, JP Su, J Birnie, J Danielewski, DA Machalek, CS Bradshaw, TRH Read, A-M Costa, SM Garland

Journal article  |  2019  |  Journal of Applied Microbiology

MACROLIDE AND FLUOROQUINOLONE RESISTANCE-ASSOCIATED MUTATIONS IN MYCOPLASMA GENITALIUM: A SYSTEMATIC REVIEW AND META-ANALYSIS

Dorothy Machalek, Yusha Tao, Hannah Shilling, Jorgen Jensen, Magnus Unemo, Gerald Murray, Eric Chow, Nicola Low, Suzanne Garland, Christopher Fairley, Lenka Vodstrcil, Jane Hocking, Lei Zhang, Catriona Bradshaw

Conference Proceedings  |  2019  |  Poster Presentations

MYCOPLASMA GENITALIUM parC AND gyrA MUTATIONS ASSOCIATED WITH MOXIFLOXACIN AND SITAFLOXACIN TREATMENT FAILURE

Gerald Murray, Catriona Bradshaw, Kaveesha Bodiyabadu, Jennifer Danielewski, Josh Birnie, Litty Tan, Elisa Mokany, Tim Read, Dorothy Machalek, Christopher Fairley, Suzanne Garland

Conference Proceedings  |  2019  |  Oral Presentations

FACTORS ASSOCIATED WITH ONCOGENIC HUMAN PAPILLOMAVIRUS PREVALENCE AMONG AUSTRALIAN WOMEN FOLLOWING VACCINE INTRODUCTION

Dorothy Machalek, Hannah Shilling, Steph Atchison, Alyssa Cornall, Julia Brotherton, Deborah Bateson, Kathleen Mcnamee, Jane Hocking, John Kaldor, Marcus Chen, Christopher Fairley, Eric Chow, S Rachel Skinner, Gerald Murray, Monica Molano, Sepehr Tabrizi, Suzanne Garland

Conference Proceedings  |  2019  |  Poster Presentations

LOW PREVALENCE OF HIGH-RISK ANAL HPV IN YOUNG GAY AND BISEXUAL MALES AFTER THE UNIVERSAL HPV VACCINATION PROGRAM IN AUSTRALIA

Eric Chow, Sepehr Tabrizi, Christopher Fairley, Rebecca Wigan, Alyssa Cornall, Steph Atchison, Dorothy Machalek, Jane Hocking, Catriona Bradshaw, Suzanne Garland, Marcus Chen

Conference Proceedings  |  2019  |  Poster Presentations

PREVALENCE OF HPV IN TEENAGE HETEROSEXUAL MALES AFTER THE INTRODUCTION OF THE GENDER-NEUTRAL VACCINATION PROGRAM IN AUSTRALIA

Eric Chow, Sepehr Tabrizi, Christopher Fairley, Rebecca Wigan, David Regan, Jane Hocking, Suzanne Garland, Julia Brotherton, Catriona Bradshaw, Alyssa Cornall, Anna McNulty, Steph Atchison, Dorothy Machalek, Louise Owen, Lewis Marshall, Darren Russell, Marcus Chen

Conference Proceedings  |  2019  |  Poster Presentations

Age-specific HPV prevalence among 116,052 women in Australia's renewed cervical screening program: A new tool for monitoring vaccine impact

Julia ML Brotherton, David Hawkes, Farhana Sultana, Michael J Malloy, Dorothy A Machalek, Megan A Smith, Suzanne M Garland, Marion Saville

Journal article  |  2019  |  Vaccine

Treatment Intensity Differences After Early-Stage Breast Cancer (ESBC) Diagnosis Depending on Participation in a Screening Program

Kenneth Elder, Carolyn Nickson, Melinda Pattanasri, Samuel Cooke, Dorothy Machalek, Allison Rose, Arlene Mou, John Paxton Collins, Allan Park, Richard De Boer, Claire Phillips, Vicki Pridmore, Helen Farrugia, G Bruce Mann

Journal article  |  2018  |  Annals of Surgical Oncology

Uptake of adjuvant breast cancer treatments recommended by multi-disciplinary meetings

Melinda Pattanasri, Kenneth Elder, Carolyn Nickson, Samuel Cooke, Dorothy Machalek, Allison Rose, Arlene Mou, John P Collins, Allan Park, Richard De Boer, Claire Phillips, Vicki Pridmore, Helen Farrugia, G Bruce Mann

Journal article  |  2018  |  ANZ Journal of Surgery

Very Low Prevalence of Vaccine Human Papillomavirus Types Among 18-to 35-Year Old Australian Women 9 Years Following Implementation of Vaccination

Dorothy A Machalek, Suzanne M Garland, Julia ML Brotherton, Deborah Bateson, Kathleen McNamee, Mary Stewart, S Rachel Skinner, Bette Liu, Alyssa M Cornall, John M Kaldor, Sepehr N Tabrizi

Journal article  |  2018  |  The Journal of Infectious Diseases

HPV genotype-specific concordance between EuroArray HPV, Anyplex II HPV28 and Linear Array HPV Genotyping test in Australian cervical samples

Alyssa M Cornall, Marin Poljak, Suzanne M Garland, Samuel Phillips, Dorothy A Machalek, Jeffrey H Tan, Michael A Quinn, Sepehr N Tabrizi

Journal article  |  2017  |  Papillomavirus Research

Using Facebook to Recruit Young Australian Men Into a Cross-Sectional Human Papillomavirus Study

Roopa Das, Dorothy A Machalek, Edmund G Molesworth, Suzanne M Garland

Journal article  |  2017  |  Journal of Medical Internet Research

Maximizing the Impact of Human Papillomavirus Vaccination

Suzanne M Garland, Dorothy A Machalek

Journal article  |  2017  |  Clinical Infectious Diseases

The performance of human papillomavirus biomarkers in predicting anal high-grade squamous intraepithelial lesions in gay and bisexual men

Fengyi Jin, Jennifer M Roberts, Andrew E Grulich, Isobel M Poynten, Dorothy A Machalek, Alyssa Cornall, Samuel Phillips, Deborah Ekman, Ross L McDonald, Richard J Hillman, David J Templeton, Annabelle Farnsworth, Suzanne M Garland, Christopher K Fairley, Sepehr N Tabrizi

Journal article  |  2017  |  AIDS

Vaccine-preventable anal human papillomavirus in Australian gay and bisexual men

I Mary Poynten, Sepehr N Tabrizi, Fengyi Jin, David J Templeton, Dorothy A Machalek, Alyssa Cornall, Samuel Phillips, Christopher K Fairley, Suzanne M Garland, Carmella Law, Andrew Carr, Richard J Hillman, Andrew E Grulich

Journal article  |  2017  |  Papillomavirus Research

Prevalence and predictors of unsatisfactory anal cytology tests in a cohort of gay and bisexual men in Sydney, Australia: baseline findings from the Study of the Prevention of Anal Cancer (SPANC)

David J Templeton, Jennifer M Roberts, I Mary Poynten, Carmella Law, Richard J Hillman, Annabelle Farnsworth, Christopher K Fairley, Sepehr N Tabrizi, Suzanne M Garland, Andrew E Grulich, Fengyi Jin

Journal article  |  2017  |  European Journal of Cancer Prevention

Anyplex II HPV28 detection and Anyplex II HPV HR detection assays are highly concordant with other commercial assays for detection of high-risk HPV genotypes in women with high grade cervical abnormalities

AM Cornall, M Poljak, SM Garland, S Phillips, JH Tan, DA Machalek, MA Quinn, SN Tabrizi

Journal article  |  2017  |  European Journal of Clinical Microbiology & Infectious Diseases

Genetic and Environmental Factors in Invasive Cervical Cancer: Design and Methods of a Classical Twin Study

Dorothy A Machalek, John D Wark, Sepehr N Tabrizi, John L Hopper, Minh Bui, Gillian S Dite, Alyssa M Cornall, Marian Pitts, Dorota Gertig, Bircan Erbas, Suzanne M Garland

Journal article  |  2017  |  Twin Research and Human Genetics

Human Papillomavirus Prevalence in Unvaccinated Heterosexual Men After a National Female Vaccination Program

Dorothy A Machalek, Eric PF Chow, Suzanne M Garland, Rebecca Wigan, Alyssa M Cornall, Christopher K Fairley, John M Kaldor, Jane S Hocking, Henrietta Williams, Anna McNulty, Charlotte Bell, Lewis Marshall, Catriona Ooi, Marcus Y Chen, Sepehr N Tabrizi

Journal article  |  2017  |  Journal of Infectious Diseases

Quadrivalent vaccine-targeted human papillomavirus genotypes in heterosexual men after the Australian female human papillomavirus vaccination programme: a retrospective observational study

Eric PF Chow, Dorothy A Machalek, Sepehr N Tabrizi, Jennifer A Danielewski, Glenda Fehler, Catriona S Bradshaw, Suzanne M Garland, Marcus Y Chen, Christopher K Fairley

Journal article  |  2017  |  The Lancet Infectious Diseases

Prevalence and risk factors associated with high-grade anal squamous intraepithelial lesions (HSIL)-AIN2 and HSIL-AIN3 in homosexual men

Dorothy A Machalek, Fengyi Jin, I Mary Poynten, Richard J Hillman, David J Templeton, Carmella Law, Jennifer M Roberts, Sepehr N Tabrizi, Suzanne M Garland, Annabelle Farnsworth, Christopher K Fairley, Andrew E Grulich

Journal article  |  2016  |  Papillomavirus Research

Attitudes, Knowledge and Factors Associated with Human Papillomavirus (HPV) Vaccine Uptake in Adolescent Girls and Young Women in Victoria, Australia

Iris LY Tung, Dorothy A Machalek, Suzanne M Garland

Journal article  |  2016  |  PLOS ONE

CpG Methylation Analysis of HPV16 in Laser Capture Microdissected Archival Tissue and Whole Tissue Sections from High Grade Anal Squamous Intraepithelial Lesions: A Potential Disease Biomarker

Monica Molano, Sepehr N Tabrizi, Suzanne M Garland, Jennifer M Roberts, Dorothy A Machalek, Samuel Phillips, David Chandler, Richard J Hillman, Andrew E Grulich, Fengyi Jin, I Mary Poynten, David J Templeton, Alyssa M Cornall

Journal article  |  2016  |  PLOS ONE

The value of a transformation zone component in anal cytology to detect HSIL

Jennifer M Roberts, Fengyi Jin, Julia K Thurloe, Deborah Ekman, Marjorie K Adams, Ross L McDonald, Clare Biro, I Mary Poynten, Andrew E Grulich, Annabelle Farnsworth

Journal article  |  2016  |  Cancer Cytopathology

Comparison of the Roche CobasA (R) 4800 HPV assay to Roche Amplicor for detection of high-risk human papillomavirus

S Phillips, AM Cornall, DA Machalek, SM Garland, D Bateson, M Garefalakis, SN Tabrizi

Journal article  |  2016  |  European Journal of Clinical Microbiology & Infectious Diseases

A Composite Cytology-Histology Endpoint Allows a More Accurate Estimate of Anal High-Grade Squamous Intraepithelial Lesion Prevalence

Dorothy A Machalek, I Mary Poynten, Fengyi Jin, Richard J Hillman, David J Templeton, Carmella Law, Jennifer M Roberts, Sepehr N Tabrizi, Suzanne M Garland, Annabelle Farnsworth, Christopher K Fairley, Andrew E Grulich

Journal article  |  2016  |  Cancer Epidemiology Biomarkers & Prevention

RAPID FALL IN QUADRIVALENT VACCINE TARGETED HUMAN PAPILLOMAVIRUS GENOTYPES IN HETEROSEXUAL MEN FOLLOWING THE AUSTRALIAN FEMALE HPV VACCINATION PROGRAMME: AN OBSERVATIONAL STUDY FROM 2004 TO 2015

Eric Chow, Dorothy Machalek, Sepehr Tabrizi, Jennifer Danielewski, Glenda Fehler, Catriona Bradshaw, Suzanne Garland, Marcus Chen, Christopher Fairley, Sandra Walker

Conference Proceedings  |  2016  |  Sexually Transmitted Infections

EUROarray human papillomavirus (HPV) assay is highly concordant with other commercial assays for detection of high-risk HPV genotypes in women with high grade cervical abnormalities

AM Cornall, M Poljak, SM Garland, S Phillips, DA Machalek, JH Tan, MA Quinn, SN Tabrizi

Journal article  |  2016  |  European Journal of Clinical Microbiology & Infectious Diseases

Reducing the burden of sexually transmissible infections in Papua New Guinea requires strengthening of clinical services and engaging men

Jane S Hocking, Cathy Vaughan, Andrew Lau, Dorothy A Machelak, Simon Graham

Journal article  |  2016  |  Sexual Health

MYCOPLASMA GENITALIUM TESTING PATTERN AND INFECTION RATES OVER A SIX-YEAR PERIOD IN MELBOURNE, AUSTRALIA

SN Tabrizi, AM Costa, A Marceglia, DA Machalek, CS Bradshaw, M Chen, CK Fairley, SM Garland

Conference Proceedings  |  2015  |  Sexually Transmitted Infections

How to best measure the effectiveness of male human papillomavirus vaccine programmes?

SM Garland, EG Molesworth, DA Machalek, AM Cornall, Sepehr N Tabrizi

Journal article  |  2015  |  Clinical Microbiology and Infection

Laser capture microdissection as a tool to evaluate human papillomavirus genotyping and methylation as biomarkers of persistence and progression of anal lesions

Alyssa M Cornall, Jennifer M Roberts, Monica Molano, Dorothy A Machalek, Samuel Phillips, Richard J Hillman, Andrew E Grulich, Fengyi Jin, I Mary Poynten, David J Templeton, Suzanne M Garland, Sepehr N Tabrizi

Journal article  |  2015  |  BMJ OPEN

The Study of the Prevention of Anal Cancer (SPANC): design and methods of a three-year prospective cohort study

Dorothy A Machalek, Andrew E Grulich, Richard J Hillman, Fengyi Jin, David J Templeton, Sepehr N Tabrizi, Suzanne M Garland, Garrett Prestage, Kirsten McCaffery, Kirsten Howard, Winnie Tong, Christopher K Fairley, Jennifer Roberts, Annabelle Farnsworth, I Mary Poynten

Journal article  |  2013  |  BMC Public Health

Anal cancer screening - Authors' reply

AE Grulich, DA Machalek, IM Poynten, F Jin, CK Fairley, SN Tabrizi, SM Garland, DJ Templeton, RJ Hillman

Journal article  |  2012  |  Lancet Oncology

Anal cancer screening Reply

Andrew E Grulich, Dorothy A Machalek, I Mary Poynten, Fengyi Jin, Christopher K Fairley, Sepehr N Tabrizi, Suzanne M Garland, David J Templeton, Richard J Hillman

Journal article  |  2012  |  LANCET ONCOLOGY

Anal human papillomavirus infection and associated neoplastic lesions in men who have sex with men: a systematic review and meta-analysis

Dorothy A Machalek, Mary Poynten, Fengyi Jin, Christopher K Fairley, Annabelle Farnsworth, Suzanne M Garland, Richard J Hillman, Kathy Petoumenos, Jennifer Roberts, Sepehr N Tabrizi, David J Templeton, Andrew E Grulich

Journal article  |  2012  |  Lancet Oncology

Hedgehog Overexpression Is Associated with Stromal Interactions and Predicts for Poor Outcome in Breast Cancer

Sandra A O'Toole, Dorothy A Machalek, Robert F Shearer, Ewan KA Millar, Radhika Nair, Peter Schofield, Duncan McLeod, Caroline L Cooper, Catriona M McNeil, Andrea McFarland, Nguyen Akira, Christopher J Ormandy, Min Ru Qiu, Brian Rabinovich, Luciano G Martelotto, Vu Duc, Gregory E Hannigan, Elizabeth A Musgrove, Daniel Christ, Robert L Sutherland, et al.

Journal article  |  2011  |  Cancer Research

Glycosaminoglycan Sulphation Affects the Seeded Misfolding of a Mutant Prion Protein

Victoria A Lawson, Brooke Lumicisi, Jeremy Welton, Dorothy Machalek, Katrina Gouramanis, Helen M Klemm, James D Stewart, Colin L Masters, David E Hoke, Steven J Collins, Andrew F Hill

Journal article  |  2010  |  PLoS One

Mouse-adapted sporadic human Creutzfeldt-Jakob disease prions propagate in cell culture

Victoria A Lawson, Laura J Velia, James D Stewart, Robyn A Sharples, Helen Klemm, Dorothy M Machalek, Colin L Masters, Roberto Cappai, Steven J Collins, Andrew F Hill

Journal article  |  2008  |  International Journal of Biochemistry and Cell Biology