Dr Dorothy Machalek

Dr Dorothy Machalek is an epidemiologist based at the Royal Women’s Hospital Centre for Women’s Infectious Diseases. Her research interests include the epidemiology of sexually transmitted infections and human papillomavirus (HPV), the use of molecular biomarkers in the prevention HPV related cancers, and evaluation of HPV vaccine impact.

Dorothy currently heads Australia’s National HPV Monitoring Program, funded by the Australian Government. The program aims to monitor the long term impact of the National HPV Vaccination Program on circulating HPV infections in Australia. Her research aims to prevent premature death due to cancers caused by HPV, by tracking and improving delivery of vaccines and screening in Australia and international, with a focus on those populations at highest risk.

Find out more about Dorothy Machalek's experience

Dorothy Machalek's highlights

FEATURED Journal article

Performance of the ResistancePlus MG diagnostic test for Mycoplasma genitalium using samples collected with Hologic Aptima Specimen Collection kits

Dorothy Machalek's selected work

Evaluating Molecular Biomarkers Of Anal Cancer Risk

Research Grant

The natural history of anal high grade squamous intraepithelial lesions in HIV positive an..

Conference Proceedings

Prevalence of human papillomavirus in teenage heterosexual males following the implementat..

Journal article

Analysis of Infection Loads in Mycoplasma genitalium Clinical Specimens by Use of a Commer..

Journal article

Population-level impact and herd effects following the introduction of human papillomaviru..

Journal article

Routine cervical screening by primary HPV testing: early findings in the renewed National ..

Journal article

Projects

Displaying the most recent project by Dorothy Machalek.

Evaluating Molecular Biomarkers Of Anal Cancer Risk

This grant provides funding for underrepresented minority graduate students to attend the Institute for Operations Research and the Manageme..

2017 - 2019

Completed

1

Projects

Project Types

Research Grant

Scholarly Works

Displaying the 42 most recent scholarly works by Dorothy Machalek.

Performance of the ResistancePlus MG diagnostic test for Mycoplasma genitalium using samples collected with Hologic Aptima Specimen Collection kits

Gerald L Murray, Jennifer Danielewski, Catriona S Bradshaw, Deborah A Williamson, Joshua Birnie, Jenny P Su, Vesna De Petra, Lit Y Tan, Rachel Wee, Dorothy A Machalek, Tim RH Read, Suzanne M Garland

Journal article | 2020 | Journal of Medical Microbiology

Introduction. Mycoplasma genitalium is a sexually transmitted organism with high levels of resistance to the recommended first..

The natural history of anal high grade squamous intraepithelial lesions in HIV positive and HIV negative gay and bisexual men

DJ Templeton, IM Poynten, F Jin, JM Roberts, CLH Law, AM Cornall, M Molano, DA Machalek, A Carr, A Farnsworth, S Tabrizi, S Phillips, CK Fairley, SM Garland, RJ Hillman, AE Grulich

Conference Proceedings | 2019 | HIV MEDICINE

Prevalence of human papillomavirus in teenage heterosexual males following the implementation of female and male school-based vaccination in Australia: 2014-2017

Eric PF Chow, Sepehr N Tabrizi, Christopher K Fairley, Rebecca Wigan, Dorothy A Machalek, David G Regan, Jane S Hocking, Suzanne M Garland, Alyssa M Cornall, Steph Atchison, Catriona S Bradshaw, Anna McNulty, Louise Owen, Lewis Marshall, Darren B Russell, John M Kaldor, Marcus Y Chen

Journal article | 2019 | Vaccine

BACKGROUND: Australia introduced a school-based human papillomavirus (HPV) vaccination program for females aged 12-13 years in 200..

Analysis of Infection Loads in Mycoplasma genitalium Clinical Specimens by Use of a Commercial Diagnostic Test

Gerald L Murray, Jennifer Danielewski, Kaveesha Bodiyabadu, Dorothy A Machalek, Catriona S Bradshaw, Anna-Maria Costa, Josh Birnie, Suzanne M Garland

Journal article | 2019 | Journal of Clinical Microbiology

Mycoplasma genitalium is a common sexually transmitted infection with a propensity to acquire resistance to commonly used antimicr..

Population-level impact and herd effects following the introduction of human papillomavirus vaccination programmes: updated systematic review and meta-analysis

Melanie Drolet, Elodie Benard, Norma Perez, Marc Brisson, Marie-Claude Boily, Hammad Ali, Vincenzo Baldo, Paul Brassard, Julia ML Brotherton, Denton Callander, Marta Checchi, Eric PF Chow, Silvia Cocchio, Tina Dalianis, Shelley L Deeks, Christian Dehlendorff, Basil Donovan, Christopher K Fairley, Elaine W Flagg, Julia W Gargano, et al.

Journal article | 2019 | The Lancet

BACKGROUND: More than 10 years have elapsed since human papillomavirus (HPV) vaccination was implemented. We did a systematic revi..

Routine cervical screening by primary HPV testing: early findings in the renewed National Cervical Screening Program

Dorothy A Machalek, Jennifer M Roberts, Suzanne M Garland, Julia Thurloe, Adele Richards, Ian Chambers, Terri Sivertsen, Annabelle Farnsworth

Journal article | 2019 | Medical Journal of Australia

OBJECTIVES: To report human papillomavirus (HPV) testing patterns and rates of oncogenic HPV-positivity for specimens submitted du..

The impact of sample storage on molecular-based detection of Mycoplasma genitalium

GL Murray, JP Su, J Birnie, J Danielewski, DA Machalek, CS Bradshaw, TRH Read, A-M Costa, SM Garland

Journal article | 2019 | Journal of Applied Microbiology

MACROLIDE AND FLUOROQUINOLONE RESISTANCE-ASSOCIATED MUTATIONS IN MYCOPLASMA GENITALIUM: A SYSTEMATIC REVIEW AND META-ANALYSIS

Dorothy Machalek, Yusha Tao, Hannah Shilling, Jorgen Jensen, Magnus Unemo, Gerald Murray, Eric Chow, Nicola Low, Suzanne Garland, Christopher Fairley, Lenka Vodstrcil, Jane Hocking, Lei Zhang, Catriona Bradshaw