Dorothy Machalek

Surveillance systems for monitoring cervical cancer elimination efforts: Focus on HPV infection, cervical dysplasia, cervical screening and treatment

Julia ML Brotherton, Cosette Wheeler, Gary M Clifford, Miriam Elfstrom, Marion Saville, John Kaldor, Dorothy A Machalek

Journal article  |  2021  |  PREVENTIVE MEDICINE

In order to achieve the global elimination of cervical cancer as a public health problem, close surveillance of progress in public..

The Natural History of Anal High-grade Squamous Intraepithelial Lesions in Gay and Bisexual Men

I Mary Poynten, Fengyi Jin, Jennifer M Roberts, David J Templeton, Carmella Law, Alyssa M Cornall, Monica Molano, Dorothy A Machalek, Andrew Carr, Annabelle Farnsworth, Sepehr Tabrizi, Samuel Phillips, Christopher K Fairley, Suzanne M Garland, Richard J Hillman, Andrew E Grulich

Journal article  |  2021  |  CLINICAL INFECTIOUS DISEASES

BACKGROUND: Gay and bisexual men (GBM) are disproportionately affected by anal cancer. Prevention is hindered by incomplete unders..

Evaluation of ResistancePlus MG FleXible, a 'near- patient' test for the detection of Mycoplasma genitalium and macrolide resistance mutations, using freshly collected clinical samples

Gerald L Murray, Michelle Doyle, Kaveesha Bodiyabadu, Lenka A Vodstrcil, Suzanne M Garland, Jennifer Danielewski, Dorothy A Machalek, Colette McGuinness, Erica L Plummer, Vesna De Petra, Deborah A Williamson, Catriona S Bradshaw

Journal article  |  2021  |  JOURNAL OF MEDICAL MICROBIOLOGY

Introduction. Mycoplasma genitalium is a sexually transmitted pathogen with increasing resistance to first- and second-line antimi..

Prevalence of mutations associated with resistance to macrolides and fluoroquinolones in Mycoplasma genitalium: a systematic review and meta-analysis

Dorothy A Machalek, Yusha Tao, Hannah Shilling, Jorgen S Jensen, Magnus Unemo, Gerald Murray, Eric PF Chow, Nicola Low, Suzanne M Garland, Lenka A Vodstrcil, Christopher K Fairley, Jane S Hocking, Lei Zhang, Catriona S Bradshaw

Journal article  |  2020  |  LANCET INFECTIOUS DISEASES

BACKGROUND: Mycoplasma genitalium is now recognised as an important bacterial sexually transmitted infection. We summarised data f..

Human Papillomavirus Genotypes in Anal High-Grade Squamous Intraepithelial Lesion (HSIL): Anal Intraepithelial Neoplasia Grades 2 (AIN2) and 3 (AIN3) Are Different

Jennifer M Roberts, Isobel M Poynten, Monica Molano, Dorothy A Machalek, Richard J Hillman, Patricia Guzman, Fengyi Jin, David J Templeton, Christopher K Fairley, Carmella Law, Suzanne M Garland, Andrew E Grulich, Alyssa M Cornall

Journal article  |  2020  |  CANCER EPIDEMIOLOGY BIOMARKERS & PREVENTION

BACKGROUND: Anal high-grade squamous intraepithelial lesion (HSIL) can be histomorphologically categorized into anal intraepitheli..

DECLINE IN HPV INFECTION AMONG YOUNG MEN WHO HAVE SEX WITH MEN FOLLOWING INTRODUCTION OF GENDER-NEUTRAL VACCINATION IN AUSTRALIA: A REPEAT CROSS-SECTIONAL STUDY

Eric Chow, Sepehr Tabrizi, Christopher Fairley, Rebecca Wigan, Dorothy Machalek, Suzanne Garland, Suzanne Garland, Steph Atchison, Jane Hocking, Catriona Bradshaw, Prisha Balgovind, Gerald Murray, Marcus Chen

Conference Proceedings  |  2020  |  SEXUALLY TRANSMITTED DISEASES

Detection of high-grade cervical disease among women referred directly to colposcopy after a positiveHPVscreening test varies with age and cytology findings

Annabelle Farnsworth, Jennifer M Roberts, Suzanne M Garland, Joanne Crescini, John M Kaldor, Dorothy A Machalek

Journal article  |  2020  |  INTERNATIONAL JOURNAL OF CANCER

Australia's new HPV-based cervical screening program is based on an algorithm that incorporates reflex cytology to guide decisions..

Moxifloxacin and Sitafloxacin Treatment Failure in Mycoplasma genitalium Infection: Association with parC Mutation G248T (S83I) and Concurrent gyrA Mutations

Gerald L Murray, Kaveesha Bodiyabadu, Jennifer Danielewski, Suzanne M Garland, Dorothy A Machalek, Christopher K Fairley, Jorgen S Jensen, Deborah A Williamson, Lit Y Tan, Elisa Mokany, Duygu Durukan, Catriona S Bradshaw

Journal article  |  2020  |  JOURNAL OF INFECTIOUS DISEASES

BACKGROUND: The basis of fluoroquinolone treatment failure for Mycoplasma genitalium is poorly understood. METHODS: To identify mu..

Adenomyosis is Associated with Patient-reported Recurrent Endometriosis.

Peter AW Rogers, Dorothy A Machalek, Jane Girline, Jacqueline Donoghue, Uri Dior, Martin Healey, Sarah J Holdsworth-Carson

Conference Proceedings  |  2020  |  REPRODUCTIVE SCIENCES

Monitoring human papillomavirus prevalence among young Australian women undergoing routine chlamydia screening

Hannah Shilling, Gerald Murray, Julia ML Brotherton, David Hawkes, Marion Saville, Terri Sivertsen, Ian Chambers, Jennifer Roberts, Annabelle Farnsworth, Suzanne M Garland, Jane S Hocking, John Kaldor, Rebecca Guy, Steph Atchison, Anna-Maria Costa, Monica Molano, Dorothy A Machalek

Journal article  |  2020  |  VACCINE

INTRODUCTION: Australia has recently implemented major changes in cervical cancer prevention policies including introduction of pr..