Roy Kong

Oral administration of the novel small molecule drug OCX063 protects against inflammation and vascular pathology in a rat diabetic retinopathy (DR) model

Roy Chze Khai Kong, Amanda Edgley, Elsa Chan, Alison J Cox, Sylwia Glowacka, Michelle Papadimitriou, Fay Lin Khong, Darren Kelly

Conference Proceedings  |  2019  |  INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE

OCX063, A Novel Small Molecule Drug, Exhibits Anti-Inflammatory and Anti-Fibrotic Properties in Retinal Cultures

Roy Chze Khai Chze Khai Kong, Alison J Cox, Sylwia Glowacka, Darren J Kelly, Fay Khong

Conference Proceedings  |  2017  |  INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE

The protective effect of OCX063 on reducing neovascularization and lesion size in a mouse model of choroidal neovascularization.

Erica L Fletcher, Alice A Brandli, Roy Kong, Fay Khong, Darren J Kelly

Conference Proceedings  |  2017  |  INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE

Mapping Key Regions of the RXFP2 Low-Density Lipoprotein Class-A Module That Are Involved in Signal Activation

Roy CK Kong, Ross AD Bathgate, Shoni Bruell, John D Wade, Paul R Gooley, Emma J Petrie

Journal article  |  2014  |  Biochemistry

The Relaxin Receptor (RXFP1) Utilizes Hydrophobic Moieties on a Signaling Surface of Its N-terminal Low Density Lipoprotein Class A Module to Mediate Receptor Activation

Roy CK Kong, Emma J Petrie, Biswaranjan Mohanty, Jason Ling, Jeremy CY Lee, Paul R Gooley, Ross AD Bathgate

Journal article  |  2013  |  JOURNAL OF BIOLOGICAL CHEMISTRY

Chimeric RXFP1 and RXFP2 Receptors Highlight the Similar Mechanism of Activation Utilizing Their N-Terminal Low-Density Lipoprotein Class A Modules.

Shoni Bruell, Roy CK Kong, Emma J Petrie, Brad Hoare, John D Wade, Daniel J Scott, Paul R Gooley, Ross AD Bathgate

Journal article  |  2013  |  Front Endocrinol (Lausanne)

Relaxin family peptide (RXFP) receptors 1 and 2 are unique G-protein coupled receptors in that they contain an N-terminal low-dens..

Membrane receptors: Structure and function of the relaxin family peptide receptors

Roy CK Kong, Patrick J Shilling, Derek K Lobb, Paul R Gooley, Ross AD Bathgate

Journal article  |  2010  |  Molecular and Cellular Endocrinology

Resolving the Unconventional Mechanisms Underlying RXFP1 and RXFP2 Receptor Function

Brigham J Hartley, Daniel J Scott, Gabrielle E Callander, Tracey N Wilkinson, Despina E Ganella, Chze K Kong, Sharon Layfield, Tania Ferraro, Emma J Petrie, Ross AD Bathgate

Conference Proceedings  |  2009  |  Annals of the new york academy of sciences

Synthesis, conformation, and activity of human insulin-like peptide 5 (INSL5)

Mohammed Akhter Hossain, Ross AD Bathgate, Chze K Kong, Fazel Shabanpoor, Suode Zhang, Linda M Haugaard-Jonsson, K Johan Rosengren, Geoffrey W Tregear, John D Wade

Journal article  |  2008  |  ChemBioChem