Michael Grayson

Australian Donation and Transplantation Biobank: A Research Biobank Integrated Within a Deceased Organ and Tissue Donation Program

Varun J Sharma, Graham Starkey, Rohit D'Costa, Fiona James, Effie Mouhtouris, Lisa Davis, Boa Zhong Wang, Angela Vago, Jaishankar Raman, Laura K Mackay, Helen Opdam, Robert Jones, M Lindsay Grayson, Dominique E Martin, Claire L Gordon

Journal article  |  2023  |  TRANSPLANTATION DIRECT

UNLABELLED: We aimed to facilitate the donation of tissue samples for research by establishing a centralized system integrated in ..

Multi-site implementation of whole genome sequencing for hospital infection control: A prospective genomic epidemiological analysis

Norelle L Sherry, Claire L Gorrie, Jason C Kwong, Charlie Higgs, Rhonda L Stuart, Caroline Marshall, Susan A Ballard, Michelle Sait, Tony M Korman, Monica A Slavin, Robyn S Lee, Maryza Graham, Marcel Leroi, Leon J Worth, Hiu Tat Chan, Torsten Seemann, M Lindsay Grayson, Benjamin P Howden

Journal article  |  2022  |  LANCET REGIONAL HEALTH-WESTERN PACIFIC

BACKGROUND: Current microbiological methods lack the resolution to accurately identify multidrug-resistant organism (MDRO) transmi..

Optimising genomic approaches for identifying vancomycin-resistant Enterococcus faecium transmission in healthcare settings

Charlie Higgs, Norelle L Sherry, Torsten Seemann, Kristy Horan, Hasini Walpola, Paul Kinsella, Katherine Bond, Deborah A Williamson, Caroline Marshall, Jason C Kwong, M Lindsay Grayson, Timothy P Stinear, Claire L Gorrie, Benjamin P Howden

Journal article  |  2022  |  NATURE COMMUNICATIONS

Vancomycin-resistant Enterococcus faecium (VREfm) is a major nosocomial pathogen. Identifying VREfm transmission dynamics permits ..

Lung-resident memory B cells established after pulmonary influenza infection display distinct transcriptional and phenotypic profiles

Hyon-Xhi Tan, Jennifer A Juno, Robyn Esterbauer, Hannah G Kelly, Kathleen M Wragg, Penny Konstandopoulos, Sheilajen Alcantara, Carolina Alvarado, Robert Jones, Graham Starkey, Boa Zhong Wang, Osamu Yoshino, Thomas Tiang, M Lindsay Grayson, Helen Opdam, Rohit D'Costa, Angela Vago, Laura K Mackay, Claire L Gordon, David Masopust, et al.

Journal article  |  2022  |  SCIENCE IMMUNOLOGY

Recent studies have established that memory B cells, largely thought to be circulatory in the blood, can take up long-term residen..

Key parameters for genomics-based real-time detection and tracking of multidrug-resistant bacteria: a systematic analysis

Claire L Gorrie, Anders Goncalves Da Silva, Danielle J Ingle, Charlie Higgs, Torsten Seemann, Timothy P Stinear, Deborah A Williamson, Jason C Kwong, M Lindsay Grayson, Norelle L Sherry, Benjamin P Howden

Journal article  |  2021  |  LANCET MICROBE

BACKGROUND: Pairwise single nucleotide polymorphisms (SNPs) are a cornerstone of genomic approaches to the inference of transmissi..

Staff to staff transmission as a driver of healthcare worker infections with COVID-19

Claire L Gordon, Jason A Trubiano, Natasha E Holmes, Kyra YL Chua, Jeff Feldman, Greg Young, Norelle L Sherry, M Lindsay Grayson, Jason C Kwong

Journal article  |  2021  |  INFECTION DISEASE & HEALTH

BACKGROUND: High rates of healthcare worker (HCW) infections due to COVID-19 have been attributed to several factors, including in..

A multi-institutional outbreak of New Delhi metallo-beta-lactamase-producing Escherichia coli with subsequent acquisition of the Klebsiella pneumoniae carbapenemase gene

Ester Solter, Jason C Kwong, Aaron Walton, Norelle Sherry, Benjamin P Howden, M Lindsay Grayson, David Schwartz, Elizabeth Temkin, Sammy Frenk, Yehuda Carmeli, Mitchell J Schwaber

Journal article  |  2021  |  INFECTION CONTROL AND HOSPITAL EPIDEMIOLOGY

We characterized 57 isolates from a 2-phase clonal outbreak of New Delhi metallo-β-lactamase-producing Eschericha coli, involving ..

The Penicillin Allergy Delabeling Program: A Multicenter Whole-of-Hospital Health Services Intervention and Comparative Effectiveness Study

Kyra YL Chua, Sara Vogrin, Susan Bury, Abby Douglas, Natasha E Holmes, Nixon Tan, Natasha K Brusco, Rebecca Hall, Belinda Lambros, Jacinta Lean, Wendy Stevenson, Misha Devchand, Kent Garrett, Karin Thursky, M Lindsay Grayson, Monica A Slavin, Elizabeth J Phillips, Jason A Trubiano

Journal article  |  2021  |  CLINICAL INFECTIOUS DISEASES

BACKGROUND: Penicillin allergies are associated with inferior patient and antimicrobial stewardship outcomes. We implemented a who..

Pilot study of a combined genomic and epidemiologic surveillance program for hospital-acquired multidrug-resistant pathogens across multiple hospital networks in Australia

Norelle L Sherry, Robyn S Lee, Claire L Gorrie, Jason C Kwong, Rhonda L Stuart, Tony M Korman, Caroline Marshall, Charlie Higgs, Hiu Tat Chan, Maryza Graham, Paul DR Johnson, Marcel J Leroi, Caroline Reed, Michael J Richards, Monica A Slavin, Leon J Worth, Benjamin P Howden, M Lindsay Grayson

Journal article  |  2021  |  INFECTION CONTROL AND HOSPITAL EPIDEMIOLOGY

OBJECTIVES: To conduct a pilot study implementing combined genomic and epidemiologic surveillance for hospital-acquired multidrug-..

Adaptive immunity to human coronaviruses is widespread but low in magnitude

Hyon-Xhi Tan, Wen Shi Lee, Kathleen M Wragg, Christina Nelson, Robyn Esterbauer, Hannah G Kelly, Thakshila Amarasena, Robert Jones, Graham Starkey, Bao Zhong Wang, Osamu Yoshino, Thomas Tiang, Michael Lindsay Grayson, Helen Opdam, Rohit D'Costa, Angela Vago, Laura K Mackay, Claire L Gordon, Adam K Wheatley, Stephen J Kent, et al.

Journal article  |  2021  |  CLINICAL & TRANSLATIONAL IMMUNOLOGY

OBJECTIVES: Endemic human coronaviruses (hCoVs) circulate worldwide but cause minimal mortality. Although seroconversion to hCoV i..