Louise Burrell

Plasma Cortisol, Aldosterone, and Ascorbic Acid Concentrations in Patients with Septic Shock do not Predict Treatment Effect of Hydrocortisone on Mortality: A Nested Cohort Study.

Jeremy Cohen, Rinaldo Bellomo, Laurent Billot, Louise Burrell, David M Evans, Simon Finfer, Naomi E Hammond, Qiang Li, David Liu, Colin McArthur, Brett McWhinney, John Moore, John Myburgh, Sandra Peake, Carel Pretorius, Dorrilyn Rajbhandari, Andrew Rhodes, Manoj Saxena, Jacobus Pj Ungerer, Morag J Young, et al.

Journal article  |  2020  |  American Journal of Respiratory and Critical Care Medicine

RATIONALE: Whether biomarkers can identify subgroups of patients with septic shock with differential treatment responses to hydroc..

Sound Science before Quick Judgement Regarding RAS Blockade in COVID-19

Matthew A Sparks, Andrew South, Paul Welling, J Matt Luther, Jordana Cohen, James Brian Byrd, Louise M Burrell, Daniel Batlle, Laurie Tomlinson, Vivek Bhalla, Michelle N Rheault, Maria Jose Soler, Sundar Swaminathan, Swapnil Hiremath

Journal article  |  2020  |  Clinical Journal of the American Society of Nephrology

Imbalance of the renin-angiotensin system may contribute to inflammation and fibrosis in IBD: a novel therapeutic target?

Mayur Garg, Simon G Royce, Chris Tikellis, Claire Shallue, Duygu Batu, Elena Velkoska, Louise M Burrell, Sheila K Patel, Lauren Beswick, Anvesh Jackson, Kaushali Britto, Matthew Lukies, Pavel Sluka, Hady Wardan, Yumiko Hirokawa, Chin Wee Tan, Maree Faux, Antony W Burgess, Patrick Hosking, Shaun Monagle, et al.

Journal article  |  2020  |  Gut

OBJECTIVE: We evaluated the influence of the renin-angiotensin system (RAS) on intestinal inflammation and fibrosis. DESIGN: Cultu..

Rigor before speculation in COVID-19 therapy

Paul A Welling, Daniel Batlle, James Brian Byrd, Louise M Burrell, Andrew M South, Matthew A Sparks

Journal article  |  2020  |  American Journal of Physiology-Lung Cellular and Molecular Physiology

Plasma ACE2 Activity Predicts Mortality in Aortic Stenosis and Is Associated With Severe Myocardial Fibrosis

Jay Ramchand, Sheila K Patel, Leighton G Kearney, George Matalanis, Omar Farouque, Piyush M Srivastava, Louise M Burrell

Journal article  |  2020  |  JACC: Cardiovascular Imaging

OBJECTIVES: This study investigated the relationship between plasma angiotensin-converting enzyme 2 (ACE2) activity levels and the..

May Measurement Month 2018: a pragmatic global screening campaign to raise awareness of blood pressure by the International Society of Hypertension (vol 40, pg 2006, 2019)

T Beaney, LM Burrell, RR Castillo, FJ Charchar, S Cro, A Damasceno, R Kruger, PM Nilsson, D Prabhakaran, AJ Ramirez, MP Schlaich, AE Schutte, M Tomaszewski, R Touyz, JG Wang, MA Weber, NR Poulter, G Burazeri, G Qirjako, E Roshi, et al.

Journal article  |  2019  |  European Heart Journal

Plasma endothelin-1 and adrenomedullin are associated with coronary artery function and cardiovascular outcomes in humans

James Theuerle, Omar Farouque, Sheran Vasanthakumar, Sheila K Patel, Louise M Burrell, David J Clark, Ali H Al-Fiadh

Journal article  |  2019  |  International Journal of Cardiology

May Measurement Month 2018: a pragmatic global screening campaign to raise awareness of blood pressure by the International Society of Hypertension

Thomas Beaney, Louise M Burrell, Rafael R Castillo, Fadi J Charchar, Suzie Cro, Albertino Damasceno, Ruan Kruger, Peter M Nilsson, Dorairaj Prabhakaran, Agustin J Ramirez, Markus P Schlaich, Aletta E Schutte, Maciej Tomaszewski, Rhian Touyz, Ji-Guang Wang, Michael A Weber, Neil R Poulter, Genc Burazeri, Gentiana Qirjako, Enver Roshi, et al.

Journal article  |  2019  |  EUROPEAN HEART JOURNAL

AIMS: Raised blood pressure (BP) is the biggest contributor to mortality and disease burden worldwide and fewer than half of those..

Winter Peaks in Heart Failure: An Inevitable or Preventable Consequence of Seasonal Vulnerability?

Simon Stewart, Trine T Moholdt, Louise M Burrell, Karen Sliwa, Ana O Mocumbi, John Jv McMurray, Ashley K Keates, John A Hawley

Journal article  |  2019  |  Cardiac Failure Review

Climate change is a major contributor to annual winter peaks in cardiovascular events across the globe. However, given the paradox..

May Measurement Month 2017: an analysis of blood pressure screening results from Australia-South-East Asia and Australasia

Revathy Carnagarin, Ricardo Fonseca, Derrin Brockman, Dagmara Hering, Vance B Matthews, Anastasia Mihailidou, Christopher Reid, Rebecca Lee, Gavin W Lambert, Louise M Burrell, James E Sharman, Xin Xia, Neil R Poulter, Thomas Beaney, Shariful M Islam, Melinda Carrington, Markus P Schlaich

Journal article  |  2019  |  EUROPEAN HEART JOURNAL SUPPLEMENTS

Classic and Nonclassic Renin-Angiotensin Systems in the Critically Ill

Laurent Bitker, Louise M Burrell

Journal article  |  2019  |  Critical Care Clinics

Prevalence and profile of "seasonal frequent flyers" with chronic heart disease: Analysis of 1598 patients and 4588 patient-years follow-up

Jordan Loader, Yih-Kai Chan, John A Hawley, Trine Moholdt, Christine F McDonald, Pardeep Jhund, Mark C Petrie, John J McMurray, Paul A Scuffham, Jay Ramchand, Louise M Burrell, Simon Stewart

Journal article  |  2019  |  International Journal of Cardiology

Development of Acute Decompensated Heart Failure Among Hospital Inpatients: Incidence, Causes and Outcomes

Luke D Plant, David McDonald Taylor, Thomas Worland, Arvind Puri, Antony Ugoni, Sheila K Patel, Douglas F Johnson, Louise M Burrell

Journal article  |  2019  |  Heart, Lung and Circulation

EFFECTS OF CLONIDINE ON THE CARDIOVASCULAR, RENAL, AND INFLAMMATORY RESPONSES TO EXPERIMENTAL BACTEREMIA

Paolo Calzavacca, Lindsea C Booth, Yugeesh R Lankadeva, Simon R Bailey, Louise M Burrell, Michael Bailey, Rinaldo Bellomo, Clive N May

Journal article  |  2019  |  SHOCK

Further studies needed before using renin-angiotensin-aldosterone system blockade for atrial fibrillation prevention in hypertrophic cardiomyopathy

Jay Ramchand, Thalys Sampaio Rodrigues, Matias B Yudi, Louise M Burrell

Journal article  |  2018  |  Heart

Renin-angiotensin inhibitors reprogram tumor immune microenvironment: A comprehensive view of the influences on anti-tumor immunity.

Dora L Vallejo-Ardila, Theodora Fifis, Louise M Burrell, Katrina Walsh, Christopher Christophi

Journal article  |  2018  |  Oncotarget

Renin-angiotensin system inhibitors (RASi) have shown potential anti-tumor effects that may have a significant impact in cancer th..

INVESTIGATION OF THE PEGUERO-LO PRESTI CRITERIA TO IMPROVE THE SENSITIVITY OF THE ELECTROCARDIOGRAM TO DIAGNOSE LEFT VENTRICULAR HYPERTROPHY IN PATIENTS WITH TYPE 2 DIABETES

Thalys Sampaio Rodrigues, Jay Ramchand, Bryan Wai, Piyush M Srivastava, Ronan O'Donnabhain, Sheila K Patel, Louise M Burrell

Conference Proceedings  |  2018  |  Journal of Hypertension

CEREBRAL ATROPHY IN PATIENTS WITH TYPE 2 DIABETES AND LEFT VENTRICULAR HYPERTROPHY: PRELIMINARY DATA FROM THE DIABETES AND DEMENTIA (D2) STUDY

Sheila Patel, Sheila K Patel, Mohamed S Khlif, Jay Ramchand, Carolina Restrepo, Elise Harrison, Amanda Shanks, Emilio Werden, Piyush M Srivastava, Elif I Ekinci, Louise M Burrell, Amy Brodtmann

Conference Proceedings  |  2018  |  Journal of Hypertension

REDUCED EXPRESSION OF CARDIAC KRUPPEL LIKE FACTOR 15 IS ASSOCIATED WITH CARDIAC HYPERTROPHY IN PATIENTS WITH AORTIC STENOSIS

Sheila Patel, Sheila K Patel, Jay Ramchand, Vincenzo Crocitti, Leighton G Kearney, Piyush M Srivastava, Louise M Burrell

Conference Proceedings  |  2018  |  Journal of Hypertension

Routine use of HbA1c amongst inpatients hospitalised with decompensated heart failure and the association of dysglycaemia with outcomes

K Khoo, J Lew, P Neef, L Kearney, L Churilov, R Robbins, A Tan, M Hachem, L Owen-Jones, Q Lam, GK Hart, A Wilson, P Sumithran, D Johnson, PM Srivastava, O Farouque, LM Burrell, JD Zajac, EI Ekinci

Journal article  |  2018  |  SCIENTIFIC REPORTS

Elevated plasma angiotensin converting enzyme 2 activity is an independent predictor of major adverse cardiac events in patients with obstructive coronary artery disease

J Ramchand, SK Patel, PM Srivastava, O Farouque, LM Burrell

Conference Proceedings  |  2018  |  EUROPEAN HEART JOURNAL

Role of novel biomarkers to improve risk stratification in aortic stenosis: focus on plasma ACE2 activity

J Ramchand, SK Patel, LG Kearney, G Matalanis, O Farouque, PM Srivastava, LM Burrell

Conference Proceedings  |  2018  |  EUROPEAN HEART JOURNAL

The small molecule drug diminazene aceturate inhibits liver injury and biliary fibrosis in mice

Indu G Rajapaksha, Kai Y Mak, Ping Huang, Louise M Burrell, Peter W Angus, Chandana B Herath

Journal article  |  2018  |  SCIENTIFIC REPORTS

Left ventricular hypertrophy in experimental chronic kidney disease is associated with reduced expression of cardiac Kruppel-like factor 15

Sheila K Patel, Elena Velkoska, Daniel Gayed, Jay Ramchand, Jessica Lesmana, Louise M Burrell

Journal article  |  2018  |  BMC Nephrology

May Measurement Month 2017: an analysis of blood pressure screening results worldwide

Thomas Beaney, Aletta E Schutte, Maciej Tomaszewski, Cono Ariti, Louise M Burrell, Rafael R Castillo, Fadi J Charchar, Albertino Damasceno, Ruan Kruger, Daniel T Lackland, Peter M Nilsson, Dorairaj Prabhakaran, Agustin J Ramirez, Markus P Schlaich, Jiguang Wang, Michael A Weber, Neil R Poulter

Journal article  |  2018  |  The Lancet Global Health

Low-Dose Levothyroxine Reduces Intrahepatic Lipid Content in Patients With Type 2 Diabetes Mellitus and NAFLD

Eveline Bruinstroop, Rinkoo Dalan, Yang Cao, Yong Mong Bee, Kurumbian Chandran, Li Wei Cho, Shui Boon Soh, Eng Kiong Teo, Sue-Anne Toh, Melvin Khee Shing Leow, Rohit A Sinha, Suresh Anand Sadananthan, Navin Michael, Heather M Stapleton, Christopher Leung, Peter W Angus, Sheila K Patel, Louise M Burrell, Su Chi Lim, Chee Fang Sum, et al.

Journal article  |  2018  |  The Journal of Clinical Endocrinology & Metabolism

Elevated plasma angiotensin converting enzyme 2 activity is an independent predictor of major adverse cardiac events in patients with obstructive coronary artery disease

Jay Ramchand, Sheila K Patel, Piyush M Srivastava, Omar Farouque, Louise M Burrell

Journal article  |  2018  |  PLOS ONE

Clinical perspective on antihypertensive drug Treatment in Adults with Grade 1 Hypertension and Low-to-Moderate Cardiovascular Risk: An international expert consultation

Alberto Morales-Salinas, Antonio Coca, Michael H Olsen, Ramiro Sanchez, Weimar K Sebba-Barroso, Richard Kones, Vicente Bertomeu-Martinez, Javier Sobrino, Luis Alcocer, Daniel J Pineiro, Fernando Lanas, Carlos A Machado, Fernando Aguirre-Palacios, Jose Ortellado, Gonzalo Perez, Rodrigo Sabio, Orlando Landrove, Delfin Rodriguez, Alfredo Duenas-Herrera, Ayelen Rodriguez-Portelles, et al.

Journal article  |  2018  |  Current Problems in Cardiology

Kruppel-Like Factor 15 Is Critical for the Development of Left Ventricular Hypertrophygj

Sheila K Patel, Jay Ramchand, Vincenzo Crocitti, Louise M Burrell

Journal article  |  2018  |  INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Left ventricular hypertrophy and cognitive function: a systematic review

C Restrepo, SK Patel, V Rethnam, E Werden, J Ramchand, L Churilov, LM Burrell, A Brodtmann

Journal article  |  2018  |  Journal of Human Hypertension

Starting beta-blockers during exacerbations of chronic obstructive pulmonary disease Author reply

Pieter A Neef, Louise M Burrell, Christine F McDonald, Louis B Irving, Douglas F Johnson, Daniel P Steinfort

Journal article  |  2018  |  Internal Medicine Journal

Sacubitril/valsartan: beyond natriuretic peptides

Jagdeep SS Singh, Louise M Burrell, Myriam Cherif, Iain B Squire, Andrew L Clark, Chim C Lang

Journal article  |  2017  |  Heart

The Peguero-Lo Presti Electrocardiographic Criteria Predict All-Cause Mortality in Patients With Aortic Stenosis

Jay Ramchand, Thalys Sampaio Rodrigues, Leighton G Kearney, Sheila K Patel, Piyush M Srivastava, Louise M Burrell

Journal article  |  2017  |  Journal of the American College of Cardiology

Commencement of cardioselective beta-blockers during hospitalisation for acute exacerbations of chronic obstructive pulmonary disease

Pieter A Neef, Louise M Burrell, Christine F McDonald, Louis B Irving, Douglas F Johnson, Daniel P Steinfort

Journal article  |  2017  |  Internal Medicine Journal

Increased plasma ACE2 activity is a marker of subclinical LV systolic dysfunction in patients with aortic stenosis

J Ramchand, SK Patel, LG Kearney, E Velkoska, G Matalanis, O Farouque, PM Srivastava, LM Burrell

Conference Proceedings  |  2017  |  EUROPEAN HEART JOURNAL

Angiotensin converting enzyme 2 activity and human atrial fibrillation: increased plasma angiotensin converting enzyme 2 activity is associated with atrial fibrillation and more advanced left atrial structural remodelling

Tomos E Walters, Jonathan M Kalman, Sheila K Patel, Megan Mearns, Elena Velkoska, Louise M Burrell

Journal article  |  2017  |  Europace

Plasma ACE2 activity is a novel and independent predictor of all-cause mortality in patients with aortic stenosis

J Ramchand, SK Patel, LG Kearney, E Velkoska, G Matalanis, O Farouque, PM Srivastava, LM Burrell

Conference Proceedings  |  2017  |  EUROPEAN HEART JOURNAL

Experimental and Human Evidence for Lipocalin-2 (Neutrophil Gelatinase-Associated Lipocalin [NGAL]) in the Development of Cardiac Hypertrophy and heart failure

Francine Z Marques, Priscilla R Prestes, Sean G Byars, Scott C Ritchie, Peter Wurtz, Sheila K Patel, Scott A Booth, Indrajeetsinh Rana, Yosuke Minoda, Stuart P Berzins, Claire L Curl, James R Bell, Bryan Wai, Piyush M Srivastava, Antti J Kangas, Pasi Soininen, Saku Ruohonen, Mika Kahonen, Terho Lehtimaki, Emma Raitoharju, et al.

Journal article  |  2017  |  JOURNAL OF THE AMERICAN HEART ASSOCIATION

Does left ventricular hypertrophy affect cognition and brain structural integrity in type 2 diabetes? Study design and rationale of the Diabetes and Dementia (D2) study

Sheila K Patel, Carolina Restrepo, Emilio Werden, Leonid Churilov, Elif I Ekinci, Piyush M Srivastava, Jay Ramchand, Bryan Wai, Brian Chambers, Christopher J O'Callaghan, David Darby, Vladimir Hachinski, Toby Cumming, Geoff Donnan, Louise M Burrell, Amy Brodtmann

Journal article  |  2017  |  BMC ENDOCRINE DISORDERS

Genetic Variation in Kruppel like Factor 15 Is Associated with Left Ventricular Hypertrophy in Patients with Type 2 Diabetes: Discovery and Replication Cohorts

Sheila K Patel, Bryan Wai, Chim C Lang, Daniel Levin, Colin NA Palmer, Helen M Parry, Elena Velkoska, Stephen B Harrap, Piyush M Srivastava, Louise M Burrell

Journal article  |  2017  |  EBIOMEDICINE

Adverse cardiac effects of exogenous angiotensin 1-7 in rats with subtotal nephrectomy are prevented by ACE inhibition

Louise M Burrell, Daniel Gayed, Karen Griggs, Sheila K Patel, Elena Velkoska

Journal article  |  2017  |  PLOS ONE

Resveratrol Inhibits Growth of Experimental Abdominal Aortic Aneurysm Associated With Upregulation of Angiotensin-Converting Enzyme 2

Corey S Moran, Erik Biros, Smriti M Krishna, Yutang Wang, Chris Tikellis, Susan K Morton, Joseph V Moxon, Mark E Cooper, Paul E Norman, Louise M Burrell, Merlin C Thomas, Jonathan Golledge

Journal article  |  2017  |  Arteriosclerosis, Thrombosis, and Vascular Biology

2016 Dietary Salt Fact Sheet and Call to Action: The World Hypertension League, International Society of Hypertension, and the International Council of Cardiovascular Prevention and Rehabilitation

Norm RC Campbell, Daniel T Lackland, Mark L Niebylski, Marcelo Orias, Kimbree A Redburn, Peter M Nilsson, Xin-Hua Zhang, Louise Burrell, Masatsugu Horiuchi, Neil R Poulter, Dorairaj Prabhakaran, Agustin J Ramirez, Ernesto L Schiffrin, Alta E Schutte, Rhian M Touyz, Ji-Guang Wang, Michael A Weber

Journal article  |  2016  |  The Journal of Clinical Hypertension

Beta-blockers are under-prescribed in patients with chronic obstructive pulmonary disease and co-morbid cardiac disease

PA Neef, CF McDonald, LM Burrell, LB Irving, DF Johnson, DP Steinfort

Journal article  |  2016  |  Internal Medicine Journal

Impact of nurse-mediated management on achieving blood pressure goal levels in primary care: Insights from the Valsartan Intensified Primary carE Reduction of Blood Pressure Study

Melinda J Carrington, Garry L Jennings, Mark Harris, Mark Nelson, Markus Schlaich, Nigel P Stocks, Louise M Burrell, John Amerena, Ferdinandus J de Looze, Carla H Swemmer, Nicol P Kurstjens, Simon Stewart

Journal article  |  2016  |  European Journal of Cardiovascular Nursing

Key alternative RAS components are reduced in inflamed colon in IBD: potential therapeutic targets

M Garg, SG Royce, C Tikellis, D Batu, C Shallue, P Sluka, H Wardan, E Velkoska, LM Burrell, M Thomas, A Mcfarlane, PR Gibson, JS Lubel

Conference Proceedings  |  2016  |  JOURNAL OF GASTROENTEROLOGY AND HEPATOLOGY

The Receptor for Advanced Glycation End Products (RAGE) Is Associated with Persistent Atrial Fibrillation

Terase F Lancefield, Sheila K Patel, Melanie Freeman, Elena Velkoska, Bryan Wai, Piyush M Srivastava, Mark Horrigan, Omar Farouque, Louise M Burrell

Journal article  |  2016  |  PLOS ONE

KRUPPEL LIKE FACTOR 15 IS ASSOCIATED WITH CARDIAC HYPERTROPHY IN AN EXPERIMENTAL MODEL OF KIDNEY DISEASE

Sheila Patel, Elena Velkoska, Louise Burrell

Conference Proceedings  |  2016  |  JOURNAL OF HYPERTENSION

Angiotensin converting enzyme 2 and diminazene: role in cardiovascular and blood pressure regulation

Elena Velkoska, Sheila K Patel, Louise M Burrell

Journal article  |  2016  |  Current Opinion in Nephrology and Hypertension

ACE2 ACTIVATION IMPROVES THE CARDIAC CONSEQUENCES OF KIDNEY DISEASE

Elena Velkoska, Jessica Lesmana, Daniel Gayad, Karen Griggs, Sheila K Patel, Louise M Burrell

Conference Proceedings  |  2016  |  Journal of Hypertension

OS 36-04 KRUPPEL LIKE FACTOR 15 IS ASSOCIATED WITH CARDIAC HYPERTROPHY IN AN EXPERIMENTAL MODEL OF KIDNEY DISEASE.

Sheila Patel, Elena Velkoska, Louise Burrell

Journal article  |  2016  |  J Hypertens

OBJECTIVE: Left ventricular hypertrophy (LVH) is prevalent in chronic kidney disease (CKD) and a major cause of cardiovascular mor..

SY 12-1 RENIN ANGIOTENSIN PATHWAY BEYOND ACE AND ANGIOTENSIN II RECEPTORS: HOW IT RELATES TO THE PATHOPHYSIOLOGY OF HYPERTENSION.

Louise Burrell

Journal article  |  2016  |  J Hypertens

The renin-angiotensin system (RAS) plays a major role in the pathogenesis of hypertension, a major risk factor for stroke, coronar..

RENIN ANGIOTENSIN PATHWAY BEYOND ACE AND ANGIOTENSIN II RECEPTORS: HOW IT RELATES TO THE PATHOPHYSIOLOGY OF HYPERTENSION

Louise Burrell

Conference Proceedings  |  2016  |  JOURNAL OF HYPERTENSION

OS 36-04 KRUPPEL LIKE FACTOR 15 IS ASSOCIATED WITH CARDIAC HYPERTROPHY IN AN EXPERIMENTAL MODEL OF KIDNEY DISEASE.

S Patel, E Velkoska, L Burrell

Journal article  |  2016  |  Journal of Hypertension

OBJECTIVE: Left ventricular hypertrophy (LVH) is prevalent in chronic kidney disease (CKD) and a major cause of cardiovascular mor..

SY 12-1 RENIN ANGIOTENSIN PATHWAY BEYOND ACE AND ANGIOTENSIN II RECEPTORS: HOW IT RELATES TO THE PATHOPHYSIOLOGY OF HYPERTENSION.

L Burrell

Journal article  |  2016  |  Journal of Hypertension

The renin-angiotensin system (RAS) plays a major role in the pathogenesis of hypertension, a major risk factor for stroke, coronar..

Diminazene Aceturate Improves Cardiac Fibrosis and Diastolic Dysfunction in Rats with Kidney Disease

Elena Velkoska, Sheila K Patel, Karen Griggs, Louise M Burrell

Journal article  |  2016  |  PLOS ONE

Is It Time to Reappraise Blood Pressure Thresholds and Targets? A Statement From the International Society of Hypertension-A Global Perspective

Michael A Weber, Neil R Poulter, Aletta E Schutte, Louise M Burrell, Masatsugu Horiuchi, Dorairaj Prabhakaran, Agustin J Ramirez, Ji-Guang Wang, Ernesto L Schiffrin, Rhian M Touyz

Journal article  |  2016  |  Hypertension

An unusual presentation of carcinomatous meningitis

Chuan T Foo, Louise M Burrell, Douglas F Johnson

Journal article  |  2016  |  Oxford Medical Case Reports

High Blood Pressure 2016: Why Prevention and Control Are Urgent and Important. The World Hypertension League, International Society of Hypertension, World Stroke Organization, International Diabetes Foundation, International Council of Cardiovascular Prevention and Rehabilitation, International Society of Nephrology

Norm R Campbell, Tej Khalsa, Daniel T Lackland, Mark L Niebylski, Peter M Nilsson, Kimbree A Redburn, Marcelo Orias, Xin-Hua Zhang, Louise Burrell, Masatsugu Horiuchi, Neil R Poulter, Dorairaj Prabhakaran, Agustin J Ramirez, Ernesto L Schiffrin, Rhian M Touyz, Ji-Guang Wang, Michael A Weber

Journal article  |  2016  |  The Journal of Clinical Hypertension

Establishing a pragmatic framework to optimise health outcomes in heart failure and multimorbidity (ARISE-HF): A multidisciplinary position statement

Simon Stewart, Barbara Riegel, Cynthia Boyd, Yasmin Ahamed, David R Thompson, Louise M Burrell, Melinda J Carrington, Andrew Coats, Bradi B Granger, Julie Hides, William S Weintraub, Debra K Moser, Victoria Vaughan Dickson, Cressida J McDermott, Ashley K Keates, Michael W Rich

Journal article  |  2016  |  INTERNATIONAL JOURNAL OF CARDIOLOGY

A Call to Regulate Manufacture and Marketing of Blood Pressure Devices and Cuffs: A Position Statement From the World Hypertension League, International Society of Hypertension and Supporting Hypertension Organizations

Norm RC Campbell, Mark Gelfer, George S Stergiou, Bruce S Alpert, Martin G Myers, Michael K Rakotz, Raj Padwal, Aletta Elisabeth Schutte, Eoin O'Brien, Daniel T Lackland, Mark L Niebylski, Peter M Nilsson, Kimbree A Redburn, Xin-Hua Zhang, Louise Burrell, Masatsugu Horiuchi, Neil R Poulter, Dorairaj Prabhakaran, Agustin J Ramirez, Ernesto L Schiffrin, et al.

Journal article  |  2016  |  The Journal of Clinical Hypertension

BENEFICIAL CARDIAC EFFECTS OF THE ANGIOTENSIN CONVERTING ENZYME 2 ACTIVATOR DIMINAZENE IN AN EXPERIMENTAL MODEL OF KIDNEY DISEASE

E Velkoska, SK Patel, K Griggs, LM Burrell

Conference Proceedings  |  2016  |  HYPERTENSION

A rare case of Behçet disease with generalised myositis, cardiomyositis and necrotising fasciitis.

Felix Ng, Fabian Joon Kiong Chiong, Russell Buchanan, Louise M Burrell

Journal article  |  2016  |  BMJ Case Reports

Behçet disease (BD) is a rare relapsing, multisystem vasculitis characterised by recurrent oral and genital ulcers, and uveitis. A..

MicroRNAs mediate the cardioprotective effect of angiotensin-converting enzyme inhibition in acute kidney injury

Indrajeetsinh Rana, Elena Velkoska, Sheila K Patel, Louise M Burrell, Fadi J Charchar

Journal article  |  2015  |  American Journal of Physiology-Renal Physiology

Alteration of the renin-angiotensin system in the circulation, terminal ileum and colon in patients with inflammatory bowel disease: a potential novel therapeutic target

M Garg, C Shallue, SG Royce, C Tikellis, P Sluka, H Wardan, E Velkoska, LM Burrell, M Thomas, A Mcfarlane, PR Gibson, JS Lubel

Conference Proceedings  |  2015  |  JOURNAL OF GASTROENTEROLOGY AND HEPATOLOGY

Upregulation of circulating components of the alternative renin-angiotensin system in inflammatory bowel disease: A pilot study

Mayur Garg, Louise M Burrell, Elena Velkoska, Karen Griggs, Peter W Angus, Peter R Gibson, John S Lubel

Journal article  |  2015  |  Journal of the Renin-Angiotensin-Aldosterone System

The Kruppel like factor 15 rs9838915 single nucleotide polymorphism is associated with left ventricular hypertrophy and heart failure in patients with type 2 diabetes

SK Patel, B Wai, PM Srivastava, LM Burrell

Conference Proceedings  |  2015  |  EUROPEAN HEART JOURNAL

Circulating receptor for advanced glycation end products (RAGE) is a risk factor for developing heart failure

T Lancefield, M Freeman, SK Patel, E Velkoska, M Horrigan, O Farouque, LM Burrell

Conference Proceedings  |  2015  |  EUROPEAN HEART JOURNAL

Relationship between Brain Natriuretic Peptide with 24-Hour Haemodynamic Parameters in Patients with Diabetes

Renata Libianto, George Jerums, Piyush M Srivastava, John Moran, Christopher O'Callaghan, Sheila K Patel, Michelle Clarke, Bryan Wai, Michelle Ord, Richard J Macisaac, Louise M Burrell, Elif I Ekinci

Conference Proceedings  |  2015  |  DIABETES

MicroRNAS MEDIATE THE PROTECTIVE EFFECT OF ANGIOTENSIN CONVERTING ENZYME INHIBITION (ACEI) ON THE HEART IN A RAT MODEL OF ACUTE KIDNEY INJURY

I Rana, E Velkoska, LM Burrell, FJ Charchar

Conference Proceedings  |  2015  |  HYPERTENSION

Shigella sonnei bacteraemia occurring in a young man with shigellosis.

Andrew Huynh, Christian McGrath, Douglas Johnson, Louise M Burrell

Journal article  |  2015  |  Case Reports

A 34-year-old man presented with a 6-day history of diarrhoea, abdominal cramps and fever. Blood cultures were initially reported ..

Longitudinal Development of Left Ventricular Diastolic Dysfunction in Patients With Type 2 Diabetes. Diabetes Care 2014;37:3092-3097

Louise M Burrell, Bryan Wai, Piyush M Srivastava, Sheila K Patel

Journal article  |  2015  |  Diabetes Care

Short-Term Treatment with Diminazene Aceturate Ameliorates the Reduction in Kidney ACE2 Activity in Rats with Subtotal Nephrectomy

Elena Velkoska, Sheila K Patel, Karen Griggs, Raelene J Pickering, Chris Tikellis, Louise M Burrell

Journal article  |  2015  |  PLOS ONE

Usefulness of Retinal Microvascular Endothelial Dysfunction as a Predictor of Coronary Artery Disease

Ali H Al-Fiadh, Tien Y Wong, Ryo Kawasaki, David J Clark, Sheila K Patel, Melanie Freeman, Andrew Wilson, Louise M Burrell, Omar Farouque

Journal article  |  2015  |  The American Journal of Cardiology

SERUM ANGIOTENSIN CONVERTING ENZYME 2 (ACE2) ACTIVITY FOLLOWING RENAL TRANSPLANTATION

A Crosthwaite, E Velkovska, M Roberts, L Burrell, F Ierino

Conference Proceedings  |  2014  |  NEPHROLOGY

From gene to protein-experimental and clinical studies of ACE2 in blood pressure control and arterial hypertension

Sheila K Patel, Elena Velkoska, Melanie Freeman, Bryan Wai, Terase F Lancefield, Louise M Burrell

Journal article  |  2014  |  FRONTIERS IN PHYSIOLOGY

ROLE OF MICRO-RNA IN CARDIOPROTECTION BY A RENIN-ANGIOTENSIN SYSTEM INHIBITOR IN AN ANIMAL MODEL OF RENAL INJURY

I Rana, E Velkoska, J Skommer, FZ Marques, S Quarrell, LM Burrell, FJ Charchar

Conference Proceedings  |  2014  |  HYPERTENSION

Effects of Renal Denervation on Regional Hemodynamics and Kidney Function in Experimental Hyperdynamic Sepsis

Paolo Calzavacca, Michael Bailey, Elena Velkoska, Louise M Burrell, Rohit Ramchandra, Rinaldo Bellomo, Clive N May

Journal article  |  2014  |  Critical Care Medicine

More rigorous protocol adherence to intensive structured management improves blood pressure control in primary care: results from the Valsartan Intensified Primary carE Reduction of Blood Pressure study

Simon Stewart, Nigel P Stocks, Louise M Burrell, Ferdinandus J de Looze, Adrian Esterman, Mark Harris, Joseph Hung, Carla H Swemmer, Nicol P Kurstjens, Garry L Jennings, Melinda J Carrington

Journal article  |  2014  |  Journal of Hypertension

Retinal microvascular structure and function in patients with risk factors of atherosclerosis and coronary artery disease

Ali H Al-Fiadh, Omar Farouque, Ryo Kawasaki, TT Nguyen, Nazim Uddin, Melanie Freeman, Sheila K Patel, Louise M Burrell, Tien Y Wong

Journal article  |  2014  |  ATHEROSCLEROSIS

The World Hypertension League and International Society of Hypertension Call on Governments, Nongovernmental Organizations, and the Food Industry to Work to Reduce Dietary Sodium

Norm Campbell, Daniel Lackland, Arun Chockalingam, Lisheng Liu, Ernesto L Schiffrin, Stephen Harrap, Rhian M Touyz, Louise Burrell, Augustin Ramirez, Roland Schmieder, Schutte Aletta, Dorairaj Prabhakaran

Journal article  |  2014  |  The Journal of Clinical Hypertension

The International Society of Hypertension and World Hypertension League call on governments, nongovernmental organizations and the food industry to work to reduce dietary sodium

Norman RC Campbell, Daniel T Lackland, Arun Chockalingam, Lisheng Liu, Stephen B Harrap, Rhian M Touyz, Louise M Burrell, Agustin J Ramirez, Roland E Schmieder, Aletta E Schutte, Dorairaj Prabhakaran, Ernesto L Schiffrin

Journal article  |  2014  |  Journal of Hypertension

Prevalence, predictors and evolution of echocardiographically defined cardiac abnormalities in adults with type 1 diabetes: an observational cohort study

Bryan Wai, Sheila K Patel, Michelle Ord, Richard J MacIsaac, George Jerums, Piyush M Srivastava, Louise M Burrell

Journal article  |  2014  |  JOURNAL OF DIABETES AND ITS COMPLICATIONS

Postprandial effects of a high salt meal on serum sodium, arterial stiffness, markers of nitric oxide production and markers of endothelial function

Kacie M Dickinson, Peter M Clifton, Louise M Burrell, P Hugh R Barrett, Jennifer B Keogh

Journal article  |  2014  |  ATHEROSCLEROSIS

Age adjusted Charlson Co-morbidity Index is an independent predictor of mortality over long-term follow-up in infective endocarditis

KJ Lu, LG Kearney, M Ord, E Jones, LM Burrell, PM Srivastava

Journal article  |  2013  |  International Journal of Cardiology

Activation of the Mas Receptor by Angiotensin-(1-7) in the Renin-Angiotensin System Mediates Mesenteric Vasodilatation in Cirrhosis

Josephine A Grace, Sabine Klein, Chandana B Herath, Michaela Granzow, Robert Schierwagen, Noemi Masing, Thomas Walther, Tilman Sauerbruch, Louise M Burrell, Peter W Angus, Jonel Trebicka

Journal article  |  2013  |  GASTROENTEROLOGY

Angiotensin-converting enzyme 2 activity in patients with chronic kidney disease

Matthew A Roberts, Elena Velkoska, Francesco L Ierino, Louise M Burrell

Journal article  |  2013  |  NEPHROLOGY DIALYSIS TRANSPLANTATION

Angiotensin-(1-7) and Kidney Disease: Friend or Foe

Elena Velkoska, Sheila K Patel, Louise M Burrell

Journal article  |  2013  |  Hypertension

Determinants of Achieving Early Blood Pressure Control with Monotherapy in a Primary Care Setting

Simon Stewart, Melinda J Carrington, Carla H Swemmer, Nicol P Kurstjens, Alex Brown, Louise M Burrell, Mark Nelson, Nigel P Stocks, Garry L Jennings

Journal article  |  2013  |  Journal of Clinical Hypertension

Progression of aortic stenosis in elderly patients over long-term follow up

LG Kearney, M Ord, BF Buxton, G Matalanis, SK Patel, LM Burrell, PM Srivastava

Journal article  |  2013  |  International Journal of Cardiology

Progression of aortic stenosis in elderly patients over long-term follow up

LG Kearney, M Ord, BF Buxton, G Matalanis, SK Patel, LM Burrell, PM Srivastava

Journal article  |  2013  |  International Journal of Cardiology

Multiple vascular reactivity measures improves our ability to predict underlying coronary artery disease

A Alfiadh, N Uddin, S Patel, A Wilson, D Clark, R Kawasaki, L Burrell, T Wong, O Farouque

Conference Proceedings  |  2013  |  European Heart Journal

Emerging markers in cardiovascular disease: Where does angiotensin-converting enzyme 2 fit in?

Sheila K Patel, Elena Velkoska, Louise M Burrell

Journal article  |  2013  |  CLINICAL AND EXPERIMENTAL PHARMACOLOGY AND PHYSIOLOGY

Cardiorenal Anemia Syndrome as a Prognosticator for Death in Heart Failure

Ken J Lu, Leighton G Kearney, David L Hare, Michelle Ord, Deidre Toia, Elizabeth Jones, Louise M Burrell, Piyush M Srivastava

Journal article  |  2013  |  American Journal of Cardiology

To TOE or not to TOE? That is the question in patients with portal hypertension and varices

Christopher Leung, Sern Wei Yeoh, Lucy Y Lim, Ray Boyapati, Adam G Testro, Rhys Vaughan, Kaye Marion, Louise M Burrell, Peter WAngus

Journal article  |  2013  |  Gut

The ACE2 gene: its potential as a functional candidate for cardiovascular disease

Louise M Burrell, Stephen B Harrap, Elena Velkoska, Sheila K Patel

Journal article  |  2013  |  Clinical Science

Age-dependent regulation of renal vasopressin V-1A and V-2 receptors in rats with genetic hypertension: implications for the treatment of hypertension

Louise M Burrell, John Risvanis, Rachael G Dean, Sheila K Patel, Elena Velkoska, Colin I Johnston

Journal article  |  2013  |  Journal of the American Society of Hypertension

Angiotensin-(1-7) reduces the perfusion pressure response to angiotensin II and methoxamine via an endothelial nitric oxide-mediated pathway in cirrhotic rat liver

Chandana B Herath, Kai Mak, Louise M Burrell, Peter W Angus

Journal article  |  2013  |  AMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGY

Combination renin-angiotensin system blockade and angiotensin-converting enzyme 2 in experimental myocardial infarction: implications for future therapeutic directions

Luke J Burchill, Elena Velkoska, Rachael G Dean, Karen Griggs, Sheila K Patel, Louise M Burrell

Journal article  |  2012  |  Clinical Science

Effect of intensive structured care on individual blood pressure targets in primary care: multicentre randomised controlled trial

Simon Stewart, Melinda J Carrington, Carla H Swemmer, Craig Anderson, Nicol P Kurstjens, John Amerena, Alex Brown, Louise M Burrell, Ferdinandus J de Looze, Mark Harris, Joseph Hung, Henry Krum, Mark Nelson, Markus Schlaich, Nigel P Stocks, Garry L Jennings

Journal article  |  2012  |  BMJ-BRITISH MEDICAL JOURNAL

Intramural generated Angiotensin 1-7 mediates splanchnic vasodilation via mas-receptor stimulation and thereby vascular dysfunction in cirrhosis

Sabine Klein, Josephine A Grace, Michaela Granzow, Robert Schierwagen, Chandana B Herath, Louise M Burrell, Peter W Angus, Tilman Sauerbruch, Jonel Trebicka

Conference Proceedings  |  2012  |  HEPATOLOGY

Circulating components of the alternative renin-angiotensin system are upregulated in patients with inflammatory bowel disease

Mayur Garg, Karen Griggs, Elena Velkoska, Ourania Rosella, Peter Angus, Louise Burrell, Peter Gibson, John S Lubel

Journal article  |  2012  |  JOURNAL OF GASTROENTEROLOGY AND HEPATOLOGY

Angiotensin-converting enzyme 2 polymorphisms and cardiovascular risk

JA Grace, LM Burrell, SK Patel

Journal article  |  2012  |  Internal Medicine Journal

Global longitudinal strain is a strong independent predictor of all-cause mortality in patients with aortic stenosis

LG Kearney, K Lu, M Ord, SK Patel, K Profitis, G Matalanis, LM Burrell, PM Srivastava

Journal article  |  2012  |  European Heart Journal

Usefulness of the Charlson Co-Morbidity Index to Predict Outcomes in Patients > 60 Years Old With Aortic Stenosis During 18 Years of Follow-Up

Leighton Kearney, Michelle Ord, Brian Buxton, George Matalanis, Sheila Patel, Louise Burrell, Piyush Srivastava

Journal article  |  2012  |  American Journal of Cardiology

Update on new aspects of the renin-angiotensin system in liver disease: clinical implications and new therapeutic options

Josephine A Grace, Chandana B Herath, Kai Yan Mak, Louise M Burrell, Peter W Angus

Journal article  |  2012  |  Clinical Science

A Comparison of Precipitants and Mortality When Acute Decompensated Heart Failure Occurs in the Community and Hospital Settings

D McD Taylor, M Ng Tang Fui, AR Chung, L Gani, JD Zajac, LM Burrell

Journal article  |  2012  |  Heart, Lung and Circulation

ANGIOTENSIN CONVERTING ENZYME 2 IN CHRONIC KIDNEY DISEASE

MA Roberts, E Velkoska, FL Ierino, LM Burrell

Journal article  |  2012  |  NEPHROLOGY

Angiotensin-converting enzyme 2 regulates renal atrial natriuretic peptide through angiotensin-(1-7)

Stella Bernardi, Wendy C Burns, Barbara Toffoli, Raelene Pickering, Maryio Sakoda, Despina Tsorotes, Edward Grixti, Elena Velkoska, Louise M Burrell, Colin Johnston, Merlin C Thomas, Bruno Fabris, Christos Tikellis

Journal article  |  2012  |  Clinical Science

N-Terminal Pro-Brain Natriuretic Peptide and Angiotensin-Converting Enzyme-2 Levels and Their Association With Postoperative Cardiac Complications After Emergency Orthopedic Surgery

Carol P Chong, Wen Kwang Lim, Elena Velkoska, William J van Gaal, Julie E Ryan, Judy Savige, Louise M Burrell

Journal article  |  2012  |  American Journal of Cardiology

The CTGF gene-945 G/C polymorphism is not associated with cardiac or kidney complications in subjects with type 2 diabetes

Sheila K Patel, Bryan Wai, Richard J MacIsaac, Sharon Grant, Elena Velkoska, Michelle Ord, Sianna Panagiotopoulos, George Jerums, Piyush M Srivastava, Louise M Burrell

Journal article  |  2012  |  Cardiovascular Diabetology

Chronic kidney disease: cardiac and renal angiotensin-converting enzyme (ACE) 2 expression in rats after subtotal nephrectomy and the effect of ACE inhibition

LM Burrell, L Burchill, RG Dean, K Griggs, SK Patel, E Velkoska

Journal article  |  2012  |  EXPERIMENTAL PHYSIOLOGY

Characterization and significance of ACE2 and Mas receptor in human colon adenocarcinoma

Stella Bernardi, Cristina Zennaro, Silvia Palmisano, Elena Velkoska, Nicoletta Sabato, Barbara Toffoli, Greta Giacomel, Luigi Buri, Fabrizio Zanconati, Giuseppe Bellini, Louise M Burrell, Nicolo De Manzini, Bruno Fabris

Journal article  |  2012  |  Journal of Renin-Angiotensin-Aldosterone System

Beta blocker use in subjects with type 2 diabetes mellitus and systolic heart failure does not worsen glycaemic control

Bryan Wai, Leighton G Kearney, David L Hare, Michelle Ord, Louise M Burrell, Piyush M Srivastava

Journal article  |  2012  |  Cardiovascular Diabetology

Normalization of ejection fraction in subjects with systolic heart failure. Is it really normal? A myocardial deformation study

Bryan Wai, Leighton G Kearney, Louise M Burrell, Michelle Ord, Piyush M Srivastava

Journal article  |  2012  |  International Journal of Cardiology

Review article: the pathophysiological roles of the renin-angiotensin system in the gastrointestinal tract

M Garg, PW Angus, LM Burrell, C Herath, PR Gibson, JS Lubel

Journal article  |  2012  |  Alimentary Pharmacology and Therapeutics

Association of ACE2 Genetic Variants With Blood Pressure, Left Ventricular Mass, and Cardiac Function in Caucasians With Type 2 Diabetes

Sheila K Patel, Bryan Wai, Michelle Ord, Richard J MacIsaac, Sharon Grant, Elena Velkoska, Sianna Panagiotopoulos, George Jerums, Piyush M Srivastava, Louise M Burrell

Journal article  |  2012  |  American Journal of Hypertension

INCREASED FORMATION OF SPLANCHNIC VASCULAR ANGIOTENSIN-(1-7) FROM ANGIOTENSIN I AND ANGIOTENSIN II IS MEDIATED BY ANGIOTENSIN CONVERTING ENZYME-2 IN EXPERIMENTAL CIRRHOSIS AND PORTAL HYPERTENSION

Josephine A Grace, Chandana B Herath, Zhiyuan Jia, Louise M Burrell, Peter W Angus

Conference Proceedings  |  2011  |  HEPATOLOGY

Increased formation of splanchnic vascular angiotensin-(1-7) from angiotensin I and angiotensin II is mediated by angiotensin converting enzyme-2 in experimental cirrhosis and portal hypertension

JA Grace, Z Jia, CB Herath, LM Burrell, PW Angus

Journal article  |  2011  |  JOURNAL OF GASTROENTEROLOGY AND HEPATOLOGY

Angiotensin converting enzyme 2: a novel marker of coronary artery disease in man

M Freeman, SK Patel, T Lancefield, E Velkoska, K Griggs, R Dean, A Al-Fiadh, M Horrigan, HMO Farouque, LM Burrell

Conference Proceedings  |  2011  |  EUROPEAN HEART JOURNAL

Angiotensin-(1-7) infusion is associated with increased blood pressure and adverse cardiac remodelling in rats with subtotal nephrectomy

Elena Velkoska, Rachael G Dean, Karen Griggs, Luke Burchill, Louise M Burrell

Journal article  |  2011  |  Clinical Science

With the "Universal Definition," Measurement of Creatine Kinase-Myocardial Band Rather Than Troponin Allows More Accurate Diagnosis of Periprocedural Necrosis and Infarction After Coronary Intervention

Chris CS Lim, William J van Gaal, Luca Testa, Florim Cuculi, Jayanth R Arnold, Theodoros Karamitsos, Jane M Francis, Steffen E Petersen, Janet E Digby, Stephen Westaby, Charalambos Antoniades, Rajesh K Kharbanda, Louise M Burrell, Stefan Neubauer, Adrian P Banning

Journal article  |  2011  |  Journal of the American College of Cardiology

Validation of rapid automated tissue synchronization imaging for the assessment of cardiac dyssynchrony in sinus and non-sinus rhythm

Leighton G Kearney, Bryan Wai, Michelle Ord, Louise M Burrell, David O'Donnell, Piyush M Srivastava

Journal article  |  2011  |  Europace

Advanced Glycation Urinary Protein-Bound Biomarkers and Severity of Diabetic Nephropathy in Man

Melinda T Coughlan, Sheila K Patel, George Jerums, Sally A Penfold, Nguyen Tuong-Vi, Karly C Sourris, Sianna Panagiotopoulos, Piyush M Srivastava, Mark E Cooper, Louise M Burrell, Richard J MacIsaac, Josephine M Forbes

Journal article  |  2011  |  American Journal of Nephrology

ANGIOTENSIN-(1-7) IS A MESENTERIC VASODILATOR IN EXPERIMENTAL CIRRHOSIS

Josephine A Grace, Zhiyuan Jia, Chandana B Herath, Louise M Burrell, Peter W Angus

Conference Proceedings  |  2010  |  HEPATOLOGY

Angiotensin-(1-7) is a mesenteric vasodilator in experimental cirrhosis

JA Grace, Z Jia, CB Herath, LM Burrell, PW Angus

Journal article  |  2010  |  JOURNAL OF GASTROENTEROLOGY AND HEPATOLOGY

Angiotensin-(1-7) reduces portal pressure via guanylate cyclase-dependent nitric oxide but angiotensin ii receptor independent pathway in cirrhotic rat liver

CB Herath, K Mak, Z Jia, LM Burrell, PW Angus

Journal article  |  2010  |  JOURNAL OF GASTROENTEROLOGY AND HEPATOLOGY

Usefulness of N-Terminal Pro-Brain Natriuretic Peptide to Predict Postoperative Cardiac Complications and Long-Term Mortality After Emergency Lower Limb Orthopedic Surgery

Carol P Chong, Julie E Ryan, William J van Gaal, Que T Lam, Rabindra N Sinnappu, Louise M Burrell, Judy Saviae, Wen Kwang Lim

Journal article  |  2010  |  American Journal of Cardiology

Angiotensin II mediates epithelial-to-mesenchymal transformation in tubular cells by ANG 1-7/MAS-1-dependent pathways

WC Burns, E Velkoska, R Dean, LM Burrell, MC Thomas

Journal article  |  2010  |  American Journal of Physiology: Renal Physiology

CIRCULATING HIGH MOLEULAR WEIGHT RAGE LIGANDS ACTIVATE PATHOGENIC PATHWAYS IMPLICATED IN THE DEVELOPMENT OF DIABETIC NEPHROPATHY

S Penfold, M Coughlan, S Patel, P Srivastava, K Sourris, D Steer, D Webster, M Thomas, R MacIsaac, G Jerums, L Burrell, M Cooper, J Forbes

Journal article  |  2010  |  NEPHROLOGY

ACE inhibition reduces infarction in normotensive but not hypertensive rats: correlation with cortical ACE activity

Michelle J Porritt, Michelle Chen, Sarah SJ Rewell, Rachael G Dean, Louise M Burrell, David W Howells

Journal article  |  2010  |  Journal of Cerebral Blood Flow and Metabolism

Circulating high-molecular-weight RAGE ligands activate pathways implicated in the development of diabetic nephropathy

Sally A Penfold, Melinda T Coughlan, Sheila K Patel, Piyush M Srivastava, Karly C Sourris, David Steer, Diane E Webster, Merlin C Thomas, Richard J MacIsaac, George Jerums, Louise M Burrell, Mark E Cooper, Josephine M Forbes

Journal article  |  2010  |  Kidney International

Troponin I and NT-proBNP (N-terminal pro-Brain Natriuretic Peptide) Do Not Predict 6-Month Mortality in Frail Older Patients Undergoing Orthopedic Surgery

Carol P Chong, William J van Goal, Julie E Ryan, Louise M Burrell, Judy Savige, Wen Kwang Lim

Journal article  |  2010  |  Journal of the American Medical Directors Association

Reduction of the accumulation of advanced glycation end products by ACE inhibition in experimental diabetic nephropathy (Diabetes (2002) 51, (3274-3282))

JM Forbes, ME Cooper, V Thallas, WC Burns, MC Thomas, GC Brammar, F Lee, SL Grant, LA Burrell, G Jerums, TM Osicka

Journal article  |  2010  |  Diabetes

Reduction in renal ACE2 expression in subtotal nephrectomy in rats is ameliorated with ACE inhibition

Elena Velkoska, Rachael G Dean, Luke Burchill, Vicki Levidiotis, Louise M Burrell

Journal article  |  2010  |  CLINICAL SCIENCE

Angiotensin-(1-7), an alternative metabolite of the renin-angiotensin system, is up-regulated in human liver disease and has antifibrotic activity in the bile-duct-ligated rat

John S Lubel, Chandana B Herath, Jorge Tchongue, Josephine Grace, Zhiyuan Jia, Karen Spencer, David Casley, Peter Crowley, William Sievert, Louise M Burrell, Peter W Angus

Journal article  |  2009  |  Clinical Science

ANGIOTENSIN-(1-7) ATTENUATES ANGIOTENSIN II-INDUCED INCREASES IN HEPATIC RESISTANCE VIA NON-MAS RECEPTOR MEDIATED PATHWAY IN CIRRHOTIC RAT LIVER

Chandana B Herath, Zhiyuan Jia, Louise M Burrell, Peter W Angus

Conference Proceedings  |  2009  |  HEPATOLOGY

Dabigatran versus Warfarin in Patients with Atrial Fibrillation.

Stuart J Connolly, Michael D Ezekowitz, Salim Yusuf, John Eikelboom, Jonas Oldgren, Amit Parekh, Janice Pogue, Paul A Reilly, Ellison Themeles, Jeanne Varrone, Susan Wang, Marco Alings, Denis Xavier, Jun Zhu, Rafael Diaz, Basil S Lewis, Harald Darius, Hans-Christoph Diener, Campbell D Joyner, Lars Wallentin

Journal article  |  2009  |  NEW ENGLAND JOURNAL OF MEDICINE

Beneficial effects of ivabradine on cardiac remodelling in the diabetic hypertensive heart are mediated through modulation of connective tissue growth factor

E Velkoska, RG Dean, K Spencer, LM Burrell

Journal article  |  2009  |  EUROPEAN HEART JOURNAL

Portal pressure responses and angiotensin peptide production in rat liver are determined by relative activity of ACE and ACE2

Chandana B Herath, John S Lubel, Zhiyuan Jia, Elena Velkoska, David Casley, Lindsay Brown, Chris Tikellis, Louise M Burrell, Peter W Angus

Journal article  |  2009  |  American Journal of Physiology - Gastrointestinal and Liver Physiology

ANGIOTENSIN 1-7 INCREASES CARDIAC FIBROSIS IN RENAL INJURY

E Velkoska, RG Dean, LJ Burchill, K Griggs, LM Burrell

Conference Proceedings  |  2009  |  HYPERTENSION

ROLE FOR RENAL ANGIOTENSIN CONVERTING ENZYME 2 IN THE ADAPTION TO NEPHRON LOSS FOLLOWING SUBTOTAL NEPHRECTOMY IN THE RAT

E Velkoska, RG Dean, LJ Burchill, LM Burrell

Conference Proceedings  |  2009  |  HYPERTENSION

RENIN ANGIOTENSIN SYSTEM (RAS) BLOCKADE IMPROVES CARDIAC REMODELLING WITHOUT EFFECTS ON CARDIAC ACE2 AFTER MYOCARDIAL INFARCTION

L Burchill, R Dean, E Velkoska, K Griggs, S Patel, LM Burrell

Conference Proceedings  |  2009  |  HYPERTENSION

Quenched Fluorescent Peptide Substrates as Tools for the Discovery of Novel Cardiovascular Disease Biomarkers

A Ian Smith, Fiona J Warner, Rebecca A Lew, Mike Yarski, Barry McGrath, Louise M Burrell

Journal article  |  2009  |  Advances in Experimental Medicine and Biology

Angiotensin converting enzyme 2 (ACE2) activity in fetal calf serum: implications for cell culture research

JS Lubel, CB Herath, E Velkoska, DJ Casley, LM Burrell, PW Angus

Journal article  |  2008  |  Cytotechnology

Liver disease and the renin-angiotensin system: Recent discoveries and clinical implications

John S Lubel, Chandana B Herath, Louise M Burrell, Peter W Angus

Journal article  |  2008  |  Journal of Gastroenterology and Hepatology

Early undernutrition leads to long-lasting reductions in body weight and adiposity whereas increased intake increases cardiac fibrosis in male rats

Elena Velkoska, Timothy J Cole, Rachael G Dean, Louise M Burrell, Margaret J Morris

Journal article  |  2008  |  Journal of Nutrition

Liver disease and the renin-angiotensin system: Recent discoveries and clinical implications

John S Lubel, Chandana B Herath, Louise M Burrell, Peter W Angus

Journal article  |  2008  |  Journal of Gastroenterology and Hepatology (Australia)

PLASMA ANGIOTENSIN CONVERTING ENZYME (ACE) 2 IS A NOVEL BIOMARKER OF CARDIAC INJURY

L Burchill, E Velkoska, K Griggs, LM Burrell

Conference Proceedings  |  2008  |  HYPERTENSION

AN ABNORMAL ECHOCARDIOGRAM PREDICTS ADVERSE CARDIOVASCULAR EVENTS IN PATIENTS WITH TYPE 2 DIABETES WITHOUT MACROVASCULAR DISEASE; COMPARISON WITH BLOOD PRESSURE

JM Castro, N Anavekar, S Patel, P Srivastava, L Burrell

Conference Proceedings  |  2008  |  HYPERTENSION

RENAL INJURY CAUSES CARDIAC FIBROSIS AND INCREASES CARDIAC ACE2

E Velkoska, RG Dean, LJ Burchill, K Griggs, V Levidiotis, LM Burrell

Conference Proceedings  |  2008  |  HYPERTENSION

Association between intrarenal arterial resistance and diastolic dysfunction in type 2 diabetes

Richard J MacIsaac, Merlin C Thomas, Sianna Panagiotopoulos, Trudy J Smith, Huming Hao, D Geoffrey Matthews, George Jerums, Louise M Burrell, Piyush M Srivastava

Journal article  |  2008  |  Cardiovascular Diabetology

Co-localization of angiotensin-converting enzyme 2-, octomer-4- and CD34-positive cells in rabbit atherosclerotic plaques

Anthony Zulli, Sudarshan Rai, Brian F Buxton, Louise M Burrell, David L Hare

Journal article  |  2008  |  Experimental Physiology

Angiotensin-converting enzyme 2 catalytic activity in human plasma is masked by an endogenous inhibitor

Rebecca A Lew, Fiona J Warner, Iresha Hanchapola, Michael A Yarski, Jay Manohar, Louise M Burrell, A Ian Smith

Journal article  |  2008  |  Experimental Physiology

Acute kidney injury in the rat causes cardiac remodelling and increases angiotensin-converting enzyme 2 expression

L Burchill, E Velkoska, RG Dean, RA Lew, AI Smith, V Levidiotis, LM Burrell

Journal article  |  2008  |  Experimental Physiology

Prevalence and predictors of cardiac hypertrophy and dysfunction in patients with Type 2 diabetes

Piyush M Srivastava, Paul Calafiore, Richard J Macisaac, Sheila K Patel, Merlin C Thomas, George Jerums, Louise M Burrell

Journal article  |  2008  |  Clinical Science

ACE2 and AT4R are present in diseased human blood vessels

A Zulli, LM Burrell, BF Buxton, DL Hare

Journal article  |  2008  |  European Journal of Histochemistry

Ang 1-7 fails to potentiate acetylcholine vasodilatation in the preconstricted in situ perfused cirrhotic rat liver

JS Lubel, C Herath, Z Jia, LM Burrell, Pw Angus

Conference Proceedings  |  2008  |  GUT

New insights into the angiotensin 1-7/MAS receptor interaction from a murine model of hepatic fibrosis and hepatic stellate cell culture

JS Lubel, CB Herath, Z Jia, J Tchongue, W Sievert, LM Burrell, RW Angus

Conference Proceedings  |  2008  |  Journal of Hepatology

Angiotensin 1-7 reduces bile duct proliferation and hepatic fibrosis in the bile duct ligated rat

John S Lubel, Chandano B Herath, Zhiyuan Jia, Louise M Burrell, Peter W Angus

Conference Proceedings  |  2007  |  HEPATOLOGY

Upregulation of hepatic angiotensin-converting enzyme 2 (ACE2) and angiotensin-(1-7) levels in experimental biliary fibrosis

Chandana B Herath, Fiona J Warner, John S Lubel, Rachael G Dean, Zhiyuan Jia, Rebecca A Lew, A Ian Smith, Louise M Burrell, Peter W Angus

Journal article  |  2007  |  Hepatology

Angiotensin converting enzyme 2, a target for diabetic heart disease?

RG Dean, M Nordkamp, LJ Burchill, K Griggs, C Tikellis, S Lu, LM Burrell

Conference Proceedings  |  2007  |  HYPERTENSION

Assessement of cardiac function in experimental renal failure

LJ Burchill, E Velkoska, K Griggs, RG Dean, LM Burrell

Conference Proceedings  |  2007  |  HYPERTENSION

Quenched fluorescent peptide substrates as tools for the discovery of novel cardiovascular disease biomarkers

AI Smith, FJ Warner, M Yarski, B McGrath, LM Burrell, RA Lew

Conference Proceedings  |  2007  |  BIOPOLYMERS

Chronic liver injury is associated with the upregulation of the ACE2-angiotensin-(1-7)-Mas axis in the rat

CB Herath, JS Lubel, FJ Warner, Z Jia, RG Dean, RA Lew, IA Smith, LM Burrell, PW Angus

Conference Proceedings  |  2007  |  Journal of Hepatology

ACE2 and diabetic complications

Rachael G Dean, Louise M Burrell

Journal article  |  2007  |  Current Pharmaceutical Design

Guidelines for the prevention, detection and management of people with chronic heart failure in Australia 2006

Henry Krum, Michael V Jelinek, Simon Stewart, Andrew Sindone, John J Atherton, Anna L Hawkes

Journal article  |  2006  |  Medical Journal of Australia

Human plasma angiotensin converting enzyme-2 (ACE2); a novel cardiovascular disease biomarker?

AI Smith, F Warner, M Yarski, J Manohar, L Burrell, R Lew

Journal article  |  2006  |  MOLECULAR & CELLULAR PROTEOMICS

The balance between hepatic ACE2 & ACE determines plasma levels of vasodilator peptide angiotensin-(1-7) in experimental biliary fibrosis

CB Herath, FW Warner, JS Lubel, R Dean, R Lew, I Smith, LM Burrell, PW Angus

Journal article  |  2006  |  JOURNAL OF GASTROENTEROLOGY AND HEPATOLOGY

Upregulation of the ACE2/ANG1-7/MAS receptor axis in the bile duct ligation (BDL) model of hepatic fibrosis does not affect hepatic sinusoidal resistance

JS Lubel, CB Herath, FJ Warner, ZY Jia, LM Burrell, PW Angus

Journal article  |  2006  |  JOURNAL OF GASTROENTEROLOGY AND HEPATOLOGY

Optimizing heart failure management: An Australian experience

Peter Barlis, Richard MacIsaac, David L Hare, Louise M Burrell

Journal article  |  2006  |  International Journal of Cardiology

Optimizing heart failure management: An Australian experience

Peter Barlis, Richard MacIsaac, David L Hare, Louise M Burrell

Journal article  |  2006  |  International Journal of Cardiology

Vascular neutral endopeptidase inhibition improves endothelial function and reduces intimal hyperplasia

M BARBER, M KANAGASUNDARAM, C ANDERSON, L BURRELL, R WOODS

Journal article  |  2006  |  Cardiovascular Research

Vascular neutral endopeptidase inhibition improves endothelial function and reduces intimal hyperplasia

Melissa N Barber, Meetali Kanagasundaram, Colin R Anderson, Louise M Burrell, Robyn L Woods

Journal article  |  2006  |  Cardiovascular Research

Evidence for a functional role for angiotensin (1-7), angiotensin IV and the angiotensin II type 2 receptor in human blood vessels

A Zulli, R Widdop, B Buxton, L Burrell, D Hare

Conference Proceedings  |  2006  |  Atherosclerosis Supplements

Immunolocalization of ACE2 and AT2 Receptors in Rabbit Atherosclerotic Plaques

Anthony Zulli, Louise M Burrell, Robert E Widdop, M Jane Black, Brian F Buxton, David L Hare

Journal article  |  2006  |  Journal of Histochemistry and Cytochemistry

Immunolocalization of ACE2 and AT(2) receptors in rabbit atherosclerotic plaques

A Zulli, LM Burrell, RE Widdop, MJ Black, BF Buxton, DL Hare

Journal article  |  2006  |  Journal of Histochemistry and Cytochemistry

Guidelines for the prevention, detection and management of people with chronic heart failure in Australia 2006

undefined Krum, V JELINEK, undefined stewart, undefined sindone, J atherton, L hawkes, L BURRELL

Journal article  |  2006  |  Medical Journal of Australia

Diastolic dysfunction is associated with anaemia in patients with Type II diabetes

Piyush M Srivastava, Merlin C Thomas, Paul Calafiore, Richard J MacIsaac, George Jerums, Louise M Burrell

Journal article  |  2006  |  Clinical Science

Anaemia is common in patients with diabetes and associated with an increased risk of diabetic complications. Although the role of ..

Diastolic dysfunction is associated with anaemia in patients with Type II diabetes

PM Sristava, MC Thomas, P Calafiore, RJ MacIsaac, G Jerums, LM Burrell

Journal article  |  2006  |  Clinical Science

Chronic liver injury in rats and humans upregulates the novel enzyme angiotensin converting enzyme 2

G Paizis, C Tikellis, ME Cooper, JM Schembri, RA Lew, AI Smith, T Shaw, FJ Warner, A Zuilli, LM Burrell, PW Angus

Journal article  |  2005  |  Gut

Anti-atherosclerotic and renoprotective effects of combined angiotensin-converting enzyme and neutral endopeptidase inhibition in diabetic apolipoprotein E-knockout mice

Karin Jandeleit-Dahma, Markus Lassila, Belinda J Davis, Riccardo Candido, Colin I Johnston, Terri J Allen, Louise M Burrell, Mark E Cooper

Journal article  |  2005  |  Journal of Hypertension

Connective tissue growth factor and cardiac fibrosis after myocardial infarction

RG Dean, LC Balding, R Candido, WC Burns, ZM Cao, SM Twigg, LM Burrell

Journal article  |  2005  |  Journal of Histochemistry and Cytochemistry

An unexpected cause of macroscopic haematuria

JS Lubel, LM Burrel, V Levidiotis

Journal article  |  2005  |  Medical Journal of Australia

Soluble angiotensin converting enzyme-2 present in human plasma and urine

RA Lew, CA Hamilton, FJ Warner, MA Yarski, LM Burrell, AI Smith

Conference Proceedings  |  2005  |  FEBS JOURNAL

Glomerular permeability defect in hypertension is dependent on renin angiotensin system activation

R Candido, M Carraro, F Fior, ML Artero, C Zennaro, LM Burrell, BJ Davis, MR Cattin, M Bardelli, L Faccini, R Carretta, B Fabris

Journal article  |  2005  |  American Journal of Hypertension

Myocardial infarction increases ACE2 expression in rat and humans.

Carlos M Ferrario

Journal article  |  2005  |  European Heart Journal

Myocardial infarction increases ACE2 expression in rat and humans: reply

LM Burrell, ME Cooper, CI Johnston

Journal article  |  2005  |  European Heart Journal

Lateral vs medial mitral annular tissue Doppler in the echocardiographic assessment of diastolic function and filling pressures: which should we use?

Piyush M Srivastava, Louise M Burrell, Paul Calafiore

Journal article  |  2005  |  European Journal of Echocardiography

Tissue Doppler echocardiography (TDE) is used in the assessment of diastolic function, however, it is unclear whether the medial (..

Myocardial infarction increases ACE2 expression in rat and humans

LM Burrell, J Risvanis, E Kubota, RG Dean, PS MacDonald, S Lu, C Tikellis, SL Grant, RA Lew, AI Smith, ME Cooper, CI Johnston

Journal article  |  2005  |  European Heart Journal

An unexpected cause of macroscopic haematuria

J LUBEL, L BURRELL, V LEVIDIOTIS

Journal article  |  2005  |  Medical Journal of Australia

Thiazolidinediones and congestive heart failure - exacerbation or new onset of left ventricular dysfunction?

PM Srivastava, P Calafiore, RJ MacIsaac, DL Hare, G Jerums, LM Burrell

Journal article  |  2004  |  Diabetic Medicine

Diabetic pyomyositis: An uncommon cause of a painful leg

MYY Seah, SN Anavekar, JA Savige, LM Burrell

Journal article  |  2004  |  Diabetes Care

Diabetic pyomyositis - An uncommon cause of a painful leg

MYY Seah, SN Anavekar, JA Savige, LM Burrell

Journal article  |  2004  |  Diabetes Care

ACE2, a new regulator of the renin-angiotensin system

LM Burrell, CI Johnston, C Tikellis, ME Cooper

Journal article  |  2004  |  Trends in Endocrinology and Metabolism

Localisation of ACE, ACE2 and the AT(2) receptor in rabbit atherosclerotic plaques

A Zulli, RE Widdop, LM Burrell, MJ Black, BF Buxton, DL Hare

Conference Proceedings  |  2004  |  CLINICAL AND EXPERIMENTAL PHARMACOLOGY AND PHYSIOLOGY

ACE2, a new regulator of the renin–angiotensin system

Louise M Burrell, Colin I Johnston, Christos Tikellis, Mark E Cooper

Journal article  |  2004  |  Trends in Endocrinology and Metabolism

Chronic liver injury up-regulates the novel enzyme ACE2 in rat and man

G Paizis, C Tikellis, ME Cooper, JM Pete, LM Burrell, PW Angus

Conference Proceedings  |  2004  |  Journal of Hepatology

Erratum: Up-regulation of components of the renin-angiotensin system in the bile duct-ligated rat liver (Gastroenterology (2002) 123 (1667-1676))

G Paizis, ME Cooper, JM Schembri, C Tikellis, LM Burrell, PW Angus

Journal article  |  2004  |  Gastroenterology

Cardiorenal protective effects of vasopeptidase inhibition with omapatrilat in hypertensive transgenic (mREN-2)27 rats

SA Mifsud, LM Burrell, E Kubota, K Jaworski, ME Cooper, JL Wilkinson-Berka

Journal article  |  2004  |  Clinical and Experimental Hypertension

Differential tissue and enzyme inhibitory effects of the vasopeptidase inhibitor omapatrilat in the rat

E Kubota, RG Dean, RA Hubner, DJ Casley, CI Johnston, LM Burrell

Journal article  |  2003  |  Clinical Science

Diabetes mellitus: a cardiovascular disease.

Riccardo Candido, Piyush Srivastava, Mark E Cooper, Louise M Burrell

Journal article  |  2003  |  Current Opinion in Investigational Drugs

Cardiovascular disease (CVD) is the major cause of morbidity and mortality in patients with diabetes mellitus (DM). The pathophysi..

Vasopressin receptor expression in the placenta

I Koukoulas, J Risvanis, RD Douglas-Denton, LM Burrell, KM Moritz, EM Wintour

Journal article  |  2003  |  Biology of Reproduction

Optimising heart failure management in a metropolitan teaching hosital

P Barlis, R MacIsaac, LM Burrell

Conference Proceedings  |  2003  |  CLINICAL AND EXPERIMENTAL PHARMACOLOGY AND PHYSIOLOGY

Renoprotective effects of vasopeptidase inhibition in an experimental model of diabetic nephropathy

BJ Davis, CI Johnston, LM Burrell, WC Burns, E Kubota, Z Cao, ME Cooper, TJ Allen

Journal article  |  2003  |  Diabetologia

Upregulation of cardiac insulin-like growth factor-I receptor by ACE inhibition after myocardial infarction: Potential role in remodeling

RG Dean, LA Bach, LM Burrell

Journal article  |  2003  |  Journal of Histochemistry and Cytochemistry

A breaker of advanced glycation end products attenuates diabetes-induced myocardial structural changes

R Candido, JM Forbes, MC Thomas, V Thallas, RG Dean, WC Burns, C Tikellis, RH Ritchie, SM Twigg, ME Cooper, LM Burrell

Journal article  |  2003  |  Circulation Research

Cardiovascular hypertrophy in diabetic spontaneously hypertensive rats: optimizing blockade of the renin-angiotensin system

M Lassila, BJ Davis, TJ Allen, LM Burrell, ME Cooper, ZM Cao

Journal article  |  2003  |  Clinical Science

Characterization of renal angiotensin-converting enzyme 2 in diabetic nephropathy

C Tikellis, CI Johnston, JM Forbes, WC Burns, LM Burrell, J Risvanis, ME Cooper

Journal article  |  2003  |  Hypertension

Erratum: Reduction of the accumulation of advanced glycation end products by ACE inhibition in experimental diabetic nephropathy (Diabetes (2000) 51 (3274-3282))

JM Forbes, ME Cooper, V Thallas, WC Burns, MC Thomas, GC Brammar, F Lee, SL Grant, LA Burrell, G Jerums, TM Osicka

Journal article  |  2002  |  Diabetes

Up-regulation of components of the renin-angiotensin system in the bile duct-ligated rat liver

G Paizis, ME Cooper, JM Schembri, C Tikellis, LM Burrell, PW Angus

Journal article  |  2002  |  Gastroenterology

Reduction of the accumulation of advanced glycation end products by ACE inhibition in experimental diabetic nephropathy

JM Forbes, ME Cooper, V Thallas, WC Burns, MC Thomas, GC Brammar, F Lee, SL Grant, LA Burrell, G Jerums, TM Osicka

Journal article  |  2002  |  Diabetes

Dose-dependent effects of folic acid on plasma homocysteine in a randomized trial conducted among 723 individuals with coronary heart disease.

Bruce Neal, Stephen MacMahon, Takayoshi Ohkubo, Andrew Tonkin, David Wilcken, undefined PACIFIC Study Group

Journal article  |  2002  |  European Heart Journal

AIMS: To determine the effects on homocysteine levels of two doses of folic acid compared to placebo, where the high dose is typic..

Differential tissue and enzyme inhibitory effects of the vasopeptidase inhibitor omapatrilat in rat

E Kubota, RG Dean, RA Hubner, CI Johnston, DJ Casley, LM Burrell

Conference Proceedings  |  2002  |  JOURNAL OF HYPERTENSION

Glomerular permeability defect in hypertension is dependent of renin angiotensin system activation

B Fabris, R Candido, F Fior, M Carraro, C Zennaro, LM Burrell, BJ Davis, MR Cattin, R Caretta

Conference Proceedings  |  2002  |  JOURNAL OF HYPERTENSION

Combined inhibition of neutral endopeptidase with angiotensin converting enzyme or endothelin converting enzyme in experimental diabetes

I Tikkanen, T Tikkanen, ZM Cao, TJ Allen, BJ Davis, M Lassila, D Casley, CI Johnston, LM Burrell, ME Cooper

Journal article  |  2002  |  Journal of Hypertension

Neurohormonal antagonism in heart failure; beneficial effects of vasopressin V-1a and V-2 receptor blockade and ACE inhibition

M Naitoh, J Risvanis, LC Balding, CI Johnston, LM Burrell

Journal article  |  2002  |  Cardiovascular Research

Inhibition of peptidases in the control of blood pressure

E Kubota, RG Dean, LC Balding, LM Burrell

Journal article  |  2002  |  Essays in Biochemistry

Evidence for cardioprotective, renoprotective, and vasculoprotective effects of vasopeptidase inhibitors in disease.

E Kubota, RG Dean, RA Hubner, LC Balding, CI Johnston, LM Burrell

Journal article  |  2001  |  Current Hypertension Reports

In both the natriuretic peptide and renin-angiotensin systems, peptidases play an important role in the inactivation or activation..

Upregulation of the renin-angiotensin system in hepatic fibrosis.

G Paizis, LM Burrell, JM Schembri, R Gilbert, RA Smallwood, ME Cooper, PW Angus

Journal article  |  2001  |  HEPATOLOGY

Vasopeptidase inhibition attenuates the progression of renal injury in subtotal nephrectomized rats

ZM Cao, LM Burrell, I Tikkanen, F Bonnet, ME Cooper, RE Gilbert

Journal article  |  2001  |  Kidney International

In-vitro and in-vivo inhibition of rat neutral endopeptidase and angiotensin converting enzyme with the vasopeptidase inhibitor gemopatrilat

RA Hubner, E Kubota, DJ Casley, CI Johnston, LM Burrell

Journal article  |  2001  |  Journal of Hypertension

Endocrinology and metabolism meet in the heart.

LM Burrell, JW Funder

Journal article  |  2001  |  Trends in Endocrinology and Metabolism

Beneficial renal and cardiac effects of vasopeptidase inhibition with S21402 in heart failure.

LM Burrell, NK Farina, LC Balding, CI Johnston

Journal article  |  2000  |  Hypertension

S21402 is a vasopeptidase inhibitor that simultaneously inhibits neutral endopeptidase (NEP) and angiotensin-converting enzyme (AC..

Vasopressin V1a receptor antagonism does not reverse adrenocorticotrophin-induced hypertension in the rat.

TB Fraser, SW Turner, C Wen, M Li, LM Burrell, JA Whitworth

Journal article  |  2000  |  Clinical and Experimental Pharmacology and Physiology

1. The role of arginine vasopressin (AVP) was examined in adrenocorticotrophin (ACTH)-induced hypertension in Sprague-Dawley rats ..

Antihypertensive and antihypertrophic effects of omapatrilat in SHR.

LM Burrell, J Droogh, O Man in't Veld, MD Rockell, NK Farina, CI Johnston

Journal article  |  2000  |  American Journal of Hypertension

Vasopeptidase inhibitors, such as omapatrilat are single molecules that simultaneously inhibit neutral endopeptidase (NEP) and ang..

Reversal of cardiac hypertrophy and fibrosis by S21402, a dual inhibitor of neutral endopeptidase and angiotensin converting enzyme in SHRs.

NK Farina, CI Johnston, LM Burrell

Journal article  |  2000  |  Journal of Hypertension

OBJECTIVE: The major advantage of dual inhibitors of neutral endopeptidase (NEP) and angiotensin converting enzyme (ACE) is their ..

Vasopressin receptor antagonism--a therapeutic option in heart failure and hypertension.

LM Burrell, J Risvanis, CI Johnston, M Naitoh, LC Balding

Journal article  |  2000  |  Experimental Physiology

The precise role of vasopressin in the pathophysiology of cardiovascular disease is controversial, but this peptide hormone is imp..

Passive ventricular constraint amends the course of heart failure: a study in an ovine model of dilated cardiomyopathy

JM Power, J Raman, A Dornom, SJ Farish, LM Burrell, AM Tonkin, B Buxton, CA Alferness

Journal article  |  1999  |  Cardiovascular Research

Pustular vasculitis of the hands.

AP Hall, RJ Goudge, HJ Ireton, LM Burrell

Journal article  |  1999  |  Australasian Journal of Dermatology

A case of pustular vasculitis of the hands with evidence of systemic involvement is described. A 64-year-old woman presented with ..

In vivo and in vitro characterisation of a nonpeptide vasopressin V(1A) and V(2) receptor antagonist (YM087) in the rat.

J Risvanis, M Naitoh, CI Johnston, LM Burrell

Journal article  |  1999  |  European Journal of Pharmacology

This paper reports the in vitro and in vivo characterisation of a nonpeptide, orally active, vasopressin V(1A) and V(2) receptor a..

Localization of the insulin-like growth factor system in a rat model of heart failure induced by myocardial infarction.

R Dean, SR Edmondson, LM Burrell, LA Bach

Journal article  |  1999  |  Journal of Histochemistry & Cytochemistry

Although cardiac effects of growth hormone (GH) and insulin-like growth factor (IGF)-I have been reported in experimental models o..

Vasopressin V2 receptor enhances gain of baroreflex in conscious spontaneously hypertensive rats.

DB Sampey, LM Burrell, RE Widdop

Journal article  |  1999  |  American Journal of Physiology-Regulatory, Integrative and Comparative Physiology

The aim of the present study was to determine the receptor subtype involved in arginine vasopressin (AVP)-induced modulation of ba..

Salt induces myocardial and renal fibrosis in normotensive and hypertensive rats.

HC Yu, LM Burrell, MJ Black, LL Wu, RJ Dilley, ME Cooper, CI Johnston

Journal article  |  1998  |  Circulation

BACKGROUND: The detrimental effects of high dietary salt intake may not only involve effects on blood pressure and organ hypertrop..

Dual inhibition of neutral endopeptidase and angiotensin-converting enzyme in rats with hypertension and diabetes mellitus.

T Tikkanen, I Tikkanen, MD Rockell, TJ Allen, CI Johnston, ME Cooper, LM Burrell

Journal article  |  1998  |  Hypertension

It has been suggested that combined inhibition of angiotensin-converting enzyme (ACE) and neutral endopeptidase (NEP) may lower bl..

Long-term effects of nonpeptide vasopressin V2 antagonist OPC-31260 in heart failure in the rat.

LM Burrell, PA Phillips, J Risvanis, RK Chan, KL Aldred, CI Johnston

Journal article  |  1998  |  American Journal of Physiology-Heart and Circulatory Physiology

The hormone arginine vasopressin (AVP) contributes to water retention and vasoconstriction in congestive heart failure (CHF) throu..

Long-term effects of nonpeptide vasopressin V2 antagonist OPC-31260 in heart failure in the rat

LM Burrell, PA Phillips, J Risvanis, RK Chan, KL Aldred, CI Johnston

Journal article  |  1998  |  American Journal of Physiology - Heart and Circulatory Physiology

Vasopressin V1a and V2 receptor mRNA in deoxycorticosterone acetate-salt hypertension in the rat.

J Risvanis, CI Johnston, PA Phillips, LM Burrell

Journal article  |  1998  |  Clinical Science

1. Vasopressin V1a and V2 receptors are differentially regulated in deoxycorticosterone acetate-salt hypertension. This paper inve..

Susceptibility to atrial fibrillation: a study in an ovine model of pacing-induced early heart failure.

JM Power, GA Beacom, CA Alferness, J Raman, M Wijffels, SJ Farish, LM Burrell, AM Tonkin

Journal article  |  1998  |  Journal of Cardiovascular Electrophysiology

INTRODUCTION: The development of susceptibility to atrial fibrillation (AF) is a common consequence of many forms of cardiovascula..

New hormonal blockade strategies in cardiovascular disease.

CI Johnston, M Naitoh, J Risvanis, N Farina, LM Burrell

Conference Proceedings  |  1998  |  Scandinavian Cardiovascular Journal

The circulation is controlled by overlapping haemodynamic, structural and neurohumoral mechanisms. Many hormonal vasoactive substa..

Effects of neutral endopeptidase inhibition in the rat remnant kidney model.

K Jandeleit-Dahm, LM Burrell, M Kanazawa, D Casley, B Jackson, CI Johnston

Journal article  |  1998  |  Kidney and Blood Pressure Research

The orally active neutral metalloendopeptidase (NEP) inhibitor SCH34826 was given by oral gavage in a dose of 90 mg/kg twice daily..

Thirst in elderly subjects.

M Naitoh, LM Burrell

Journal article  |  1998  |  Journal of Nutrition, Health and Aging

The hormonal changes associated with ageing, the occurrence of other medical condition and the use of medications increases the li..

Effects of chronic AVP V2R blockade in congestive heart failure in sheep. Comparison with chronic ACE inhibition.

M Naitoh, J Power, PA Phillips, J Risvanis, CI Johnston, LM Burrell

Journal article  |  1998  |  Advances in Experimental Medicine and Biology

Chapter 28 Mode of action of angiotensin converting enzyme inhibitors

LM Burrell, PA Phillips, CI Johnston

Journal article  |  1997  |  Principles of Medical Biology

Rationale and pharmacology of angiotensin II receptor antagonists: current status and future issues.

CI Johnston, M Naitoh, LM Burrell

Conference Proceedings  |  1997  |  Journal of Hypertension, Supplement

BACKGROUND: The renin-angiotensin system consists of a cascade of substrate-enzyme interactions that culminates with the productio..

Inhibition of neutral endopeptidase, the degradative enzyme for natriuretic peptides, in rat kidney after oral SCH 42495.

LM Burrell, N Farina, J Risvanis, D Woollard, D Casely, CI Johnston

Journal article  |  1997  |  Clinical Science

1. Inhibition of neutral endopeptidase (NEP), the degradative enzyme for atrial natriuretic peptide, was studied in vitro and in v..

Chronic vasopressin antagonism in two-kidney, one-clip renovascular hypertension.

LM Burrell, J Risvanis, PA Phillips, M Naitoh, CI Johnston

Conference Proceedings  |  1997  |  Clinical and Experimental Hypertension

The role of vasopressin (AVP) in the maintenance of hypertension in the rat model of two-kidney, one-clip (2K1C) Goldblatt hyperte..

Elevated vascular angiotensin converting enzyme mediates increased neointima formation after balloon injury in spontaneously hypertensive rats.

K Jandeleit-Dahm, LM Burrell, CI Johnston, KM Koch

Journal article  |  1997  |  Journal of Hypertension

OBJECTIVE: To measure the effect of hypertension on neointima formation after balloon injury of rat aorta and its association with..

Angiotensin II receptor antagonists. Potential in elderly patients with cardiovascular disease.

LM Burrell, CI Johnston

Journal article  |  1997  |  Drugs & Aging

Raised blood pressure in the elderly is not a normal consequences of aging, but is a major risk factor for cardiovascular disease...

Angiotensin and bradykinin peptides in rats with myocardial infarction.

AM Duncan, LM Burrell, A Kladis, DJ Campbell

Journal article  |  1997  |  Journal of Cardiac Failure

BACKGROUND: Angiotensin II (Ang II) stimulates cardiac hypertrophy and fibrosis, whereas bradykinin [BK-(1-9)] has cardioprotectiv..