Dick Strugnell

A retrospective study of patients with blood culture-confirmed typhoid fever in Fiji during 2014-2015: epidemiology, clinical features, treatment and outcome

Aneley Getahun, Christopher M Parry, John A Crump, Varanisese Rosa, Adam Jenney, Ravi Naidu, Kim Mulholland, Richard A Strugnell

Journal article  |  2019  |  Transactions of The Royal Society of Tropical Medicine and Hygiene

BACKGROUND: Typhoid fever is endemic in Fiji. We sought to describe the epidemiology, clinical features and case fatality risk of ..

Characterization and Purification of Mouse Mucosal-Associated Invariant T (MAIT) Cells.

Zhenjun Chen, Huimeng Wang, Criselle D'Souza, Hui-Fern Koay, Bronwyn Meehan, Zhe Zhao, Troi Pediongco, Mai Shi, Tianyuan Zhu, Bingjie Wang, Lars Kjer-Nielsen, Sidonia BG Eckle, Jamie Rossjohn, David P Fairlie, Dale I Godfrey, Richard A Strugnell, James McCluskey, Alexandra J Corbett

Journal article  |  2019  |  Current Protocols in Immunology

This unit describes the utility of various mouse models of infection and immunization for studying mucosal-associated invariant T ..

Loss of O-Linked Protein Glycosylation in Burkholderia cenocepacia Impairs Biofilm Formation and Siderophore Activity and Alters Transcriptional Regulators

Cameron C Oppy, Leila Jebeli, Miku Kuba, Clare V Oates, Richard Strugnell, Laura E Edgington-Mitchell, Miguel A Valvano, Elizabeth L Hartland, Hayley J Newton, Nichollas E Scott

Journal article  |  2019  |  mSphere

O-linked protein glycosylation is a conserved feature of the Burkholderia genus. The addition of the trisaccharide β-Gal-(1,3)-α-G..

IL-23 costimulates antigen-specific MAIT cell activation and enables vaccination against bacterial infection

Huimeng Wang, Lars Kjer-Nielsen, Mai Shi, Criselle D'Souza, Troi J Pediongco, Hanwei Cao, Lyudmila Kostenko, Xin Yi Lim, Sidonia BG Eckle, Bronwyn S Meehan, Tianyuan Zhu, Bingjie Wang, Zhe Zhao, Jeffrey YW Mak, David P Fairlie, Michele WL Teng, Jamie Rossjohn, Di Yu, Barbara Fazekas de St Groth, George Lovrecz, et al.

Journal article  |  2019  |  Science Immunology

Mucosal-associated invariant T (MAIT) cells are activated in a TCR-dependent manner by antigens derived from the riboflavin synthe..

The multifunctional enzyme S-adenosylhomocysteine/methylthioadenosine nucleosidase is a key metabolic enzyme in the virulence of Salmonella enterica var Typhimurium

Asma U Husna, Nancy Wang, Jonathan J Wilksch, Hayley J Newton, Dianna M Hocking, Iain D Hay, Simon A Cobbold, Mark R Davies, Malcolm J McConville, Trevor Lithgow, Richard A Strugnell

Journal article  |  2019  |  Biochemical Journal

Key physiological differences between bacterial and mammalian metabolism provide opportunities for the development of novel antimi..

The flagellotropic bacteriophage YSD1 targets Salmonella Typhi with a Chi-like protein tail fibre

Rhys A Dunstan, Derek Pickard, Sam Dougan, David Goulding, Claire Cormie, Joshua Hardy, Fuyi Li, Rhys Grinter, Katherine Harcourt, Lu Yu, Jiangning Song, Fernanda Schreiber, Jyoti Choudhary, Simon Clare, Fasseli Coulibaly, Richard A Strugnell, Gordon Dougan, Trevor Lithgow

Journal article  |  2019  |  Molecular Microbiology

IL-23 co-stimulation drives antigen-specific MAIT cell activation and enables vaccination against bacterial infection

H Wang, L Kjer-Nielsen, M Shi, DC Souza, T Pediongco, H Cao, L Kostenko, X Lim, S Eckle, B Meeha, B Wang, T Zhu, J Mak, D Fairlie, M Teng, J Rossjohn, D Yu, B Groth, J McCluskey, R Strugnell, et al.

Conference Proceedings  |  2019  |  EUROPEAN JOURNAL OF IMMUNOLOGY

Typhoid Fever: The More We Learn, the Less We Know (Apologies, Albert Einstein)

Nancy Wang, Leigh A Knodler, Richard A Strugnell

Journal article  |  2019  |  Cell Host & Microbe

An Outbreak of Carbapenem-Resistant and Hypervirulent Klebsiella pneumoniae in an Intensive Care Unit of a Major Teaching Hospital in Wenzhou, China

Yajie Zhao, Xiucai Zhang, Von Verge L Torres, Haiyang Liu, Andrea Rocker, Yizhi Zhang, Jiawei Wang, Lijiang Chen, Wenzi Bi, Jie Lin, Richard A Strugnell, Siqin Zhang, Trevor Lithgow, Tieli Zhou, Jianming Cao

Journal article  |  2019  |  Frontiers in Public Health

Environmental Foundations of Typhoid Fever in the Fijian Residential Setting

Aaron P Jenkins, Stacy D Jupiter, Adam Jenney, Varanisese Rosa, Alanieta Naucukidi, Namrata Prasad, Gandercillar Vosaki, Kim Mulholland, Richard Strugnell, Mike Kama, John A Crump, Pierre Horwitz

Journal article  |  2019  |  International Journal of Environmental Research and Public Health

Proximal characteristics and conditions in the residential setting deserve greater attention for their potential to influence typh..

Salmonella Effectors SseK1 and SseK3 Target Death Domain Proteins in the TNF and TRAIL Signaling Pathways

Joshua PM Newson, Nichollas E Scott, Ivy Yeuk Wah Chung, Tania Wong Fok Lung, Cristina Giogha, Jiyao Gan, Nancy Wang, Richard A Strugnell, Nathaniel F Brown, Miroslaw Cygler, Jaclyn S Pearson, Elizabeth L Hartland

Journal article  |  2019  |  Molecular & Cellular Proteomics

Atlas of group A streptococcal vaccine candidates compiled using large-scale comparative genomics

Mark R Davies, Liam McIntyre, Ankur Mutreja, Jake A Lacey, John A Lees, Rebecca J Towers, Sebastian Duchene, Pierre R Smeesters, Hannah R Frost, David J Price, Matthew TG Holden, Sophia David, Philip M Giffard, Kate A Worthing, Anna C Seale, James A Berkley, Simon R Harris, Tania Rivera-Hernandez, Olga Berking, Amanda J Cork, et al.

Journal article  |  2019  |  Nature Genetics

Systematic analysis and prediction of type IV secreted effector proteins by machine learning approaches

Jiawei Wang, Bingjiao Yang, Yi An, Tatiana Marquez-Lago, Andre Leier, Jonathan Wilksch, Qingyang Hong, Yang Zhang, Morihiro Hayashida, Tatsuya Akutsu, Geoffrey I Webb, Richard A Strugnell, Jiangning Song, Trevor Lithgow

Journal article  |  2019  |  Briefings in Bioinformatics

In the course of infecting their hosts, pathogenic bacteria secrete numerous effectors, namely, bacterial proteins that pervert ho..

Mus musculus deficient for secretory antibodies show delayed growth with an altered urinary metabolome

Kim R Simpfendorfer, Nancy Wang, Dedreia L Tull, David P De Souza, Amsha Nahid, Andre Mu, Dianna M Hocking, John S Pedersen, Odilia LC Wijburg, Malcolm J McConville, Richard A Strugnell

Journal article  |  2019  |  Molecular Medicine

Resistance mechanisms and population structure of highly drug resistant Klebsiella in Pakistan during the introduction of the carbapenemase NDM-1

Eva Heinz, Hasan Ejaz, Josefin Bartholdson Scott, Nancy Wang, Shruti Gujaran, Derek Pickard, Jonathan Wilksch, Hanwei Cao, Ikram-ul Haq, Gordon Dougan, Richard A Strugnell

Journal article  |  2019  |  Scientific Reports

Optimal protection against Salmonella infection requires noncirculating memory

Joseph M Benoun, Newton G Peres, Nancy Wang, Oanh H Pham, Victoria L Rudisill, Zachary N Fogassy, Paul G Whitney, Daniel Fernandez-Ruiz, Thomas Gebhardt, Pham Quynh-Mai, Lynn Puddington, Sammy Bedoui, Richard A Strugnell, Stephen J McSorley

Journal article  |  2018  |  Proceedings of the National Academy of Sciences

An investigation into the Omp85 protein BamK in hypervirulent Klebsiella pneumoniae, and its role in outer membrane biogenesis

Von Vergel L Torres, Eva Heinz, Christopher J Stubenrauch, Jonathan J Wilksch, Hanwei Cao, Ji Yang, Abigail Clements, Rhys A Dunstan, Felicity Alcock, Chaille T Webb, Gordon Dougan, Richard A Strugnell, Iain D Hay, Trevor Lithgow

Journal article  |  2018  |  Molecular Microbiology

MAIT cells protect against pulmonary Legionella longbeachae infection

Huimeng Wang, Criselle D'Souza, Xin Yi Lim, Lyudmila Kostenko, Troi J Pediongco, Sidonia BG Eckle, Bronwyn S Meehan, Mai Shi, Nancy Wang, Shihan Li, Ligong Liu, Jeffrey YW Mak, David P Fairlie, Yoichiro Iwakura, Jennifer M Gunnersen, Andrew W Stent, Dale I Godfrey, Jamie Rossjohn, Glen P Westall, Lars Kjer-Nielsen, et al.

Journal article  |  2018  |  Nature Communications

FusC, a member of the M16 protease family acquired by bacteria for iron piracy against plants

Rhys Grinter, Iain D Hay, Jiangning Song, Jiawei Wang, Don Teng, Vijay Dhanesakaran, Jonathan J Wilksch, Mark R Davies, Dene Littler, Simone A Beckham, Ian R Henderson, Richard A Strugnell, Gordon Dougan, Trevor Lithgow

Journal article  |  2018  |  PLOS Biology

Bastion6: a bioinformatics approach for accurate prediction of type VI secreted effectors

Jiawei Wang, Bingjiao Yang, Andre Leier, Tatiana T Marquez-Lago, Morihiro Hayashida, Andrea Rocker, Yanju Zhang, Tatsuya Akutsu, Kuo-Chen Chou, Richard A Strugnell, Jiangning Song, Trevor Lithgow

Journal article  |  2018  |  Bioinformatics

Antimicrobial-Resistant Klebsiella pneumoniae Carriage and Infection in Specialized Geriatric Care Wards Linked to Acquisition in the Referring Hospital

Claire L Gorrie, Mirjana Mirceta, Ryan R Wick, Louise M Judd, Kelly L Wyres, Nicholas R Thomson, Richard A Strugnell, Nigel F Pratt, Jill S Garlick, Kerrie M Watson, Peter C Hunter, Steve A McGloughlin, Denis W Spelman, Adam WJ Jenney, Kathryn E Holt

Journal article  |  2018  |  Clinical Infectious Diseases

Methionine biosynthesis and transport are functionally redundant for the growth and virulence of Salmonella Typhimurium

Asma Ul Husna, Nancy Wang, Simon A Cobbold, Hayley J Newton, Dianna M Hocking, Jonathan J Wilksch, Timothy A Scott, Mark R Davies, Jay C Hinton, Jai J Tree, Trevor Lithgow, Malcolm J McConville, Richard A Strugnell

Journal article  |  2018  |  Journal of Biological Chemistry

Epidemiology and risk factors for typhoid fever in Central Division, Fiji, 2014-2017: A case-control study

Namrata Prasad, Aaron P Jenkins, Lanieta Naucukidi, Varanisese Rosa, Aalisha Sahu-Khan, Mike Kama, Kylie M Jenkins, Adam WJ Jenney, Susan J Jack, Debasish Saha, Pierre Horwitz, Stacy D Jupiter, Richard A Strugnell, E Kim Mulholland, John A Crump

Journal article  |  2018  |  PLOS Neglected Tropical Diseases

Fitness cost of mcr-1-mediated polymyxin resistance in Klebsiella pneumoniae

Sue C Nang, Faye C Morris, Michael J McDonald, Mei-Ling Han, Jiping Wang, Richard A Strugnell, Tony Velkov, Jian Li

Journal article  |  2018  |  Journal of Antimicrobial Chemotherapy

The WD40 Protein BamB Mediates Coupling of BAM Complexes into Assembly Precincts in the Bacterial Outer Membrane

Sachith D Gunasinghe, Takuya Shiota, Christopher J Stubenrauch, Keith E Schulze, Chaille T Webb, Alex J Fulcher, Rhys A Dunstan, Iain D Hay, Thomas Naderer, Donna R Whelan, Toby DM Bell, Kirstin D Elgass, Richard A Strugnell, Trevor Lithgow

Journal article  |  2018  |  Cell Reports

Mucosal-Associated Invariant T Cells Augment Immunopathology and Gastritis in Chronic Helicobacter pylori Infection

Criselle D'Souza, Troi Pediongco, Huimeng Wang, Jean-Pierre Y Scheerlinck, Lyudmila Kostenko, Robyn Esterbauer, Andrew W Stent, Sidonia BG Eckle, Bronwyn S Meehan, Richard A Strugnell, Hanwei Cao, Ligong Liu, Jeffrey YW Mak, George Lovrecz, Louis Lu, David P Fairlie, Jamie Rossjohn, James McCluskey, Alison L Every, Zhenjun Chen, et al.

Journal article  |  2018  |  The Journal of Immunology

Successful treatment of biofilm infections using shock waves combined with antibiotic therapy (vol 5, 17440, 2015)

Divya Prakash Gnanadhas, Monalisha Elango, S Janardhanraj, CS Srinandan, Akshay Datey, Richard A Strugnell, Jagadeesh Gopalan, Dipshikha Chakravortty

Journal article  |  2018  |  Scientific Reports

This corrects the article DOI: 10.1038/srep17440.

Reductive evolution in outer membrane protein biogenesis has not compromised cell surface complexity in Helicobacter pylori

Chaille T Webb, Dilini Chandrapala, Siti Nurbaya Oslan, Rebecca S Bamert, Rhys D Grinter, Rhys A Dunstan, Rebecca J Gorrell, Jiangning Song, Richard A Strugnell, Trevor Lithgow, Terry Kwok

Journal article  |  2017  |  MicrobiologyOpen

Antimicrobial resistant Klebsiella pneumoniae carriage and infection in specialized geriatric care wards linked to acquisition in the referring hospital

Claire Gorrie, Mirjana Mirceta, Ryan Wick, Louise Judd, Kelly Wyres, Nicholas Thomson, Richard Strugnell, Nigel Pratt, Jill Garlick, Kerrie Watson, Peter Hunter, Steve McGloughlin, Denis Spelman, Adam Jenney, Kathryn Holt

Journal article  |  2017

Abstract Background Klebsiella pneumoniae is a leading cause of extended-spectrum beta-lactamase (ESBL) producing hospital-associa..

Phylogenetic Analysis of Klebsiella pneumoniae from Hospitalized Children, Pakistan

Hasan Ejaz, Nancy Wang, Jonathan J Wilksch, Andrew J Page, Hanwei Cao, Shruti Gujaran, Jacqueline A Keane, Trevor Lithgow, Ikram ul-Haq, Gordon Dougan, Richard A Strugnell, Eva Heinz

Journal article  |  2017  |  Emerging Infectious Diseases

Gastrointestinal Carriage Is a Major Reservoir of Klebsiella pneumoniae Infection in Intensive Care Patients

Claire L Gorrie, Mirjana Mirceta, Ryan R Wick, David J Edwards, Nicholas R Thomson, Richard A Strugnell, Nigel F Pratt, Jill S Garlick, Kerri M Watson, David V Pilcher, Steve A McGloughlin, Denis W Spelman, Adam WJ Jenney, Kathryn E Holt

Journal article  |  2017  |  Clinical Infectious Diseases

Extensively Drug-Resistant Klebsiella pneumoniae Causing Nosocomial Bloodstream Infections in China: Molecular Investigation of Antibiotic Resistance Determinants, Informing Therapy, and Clinical Outcomes

Wenzi Bi, Haiyang Liu, Rhys A Dunstan, Bin Li, Von Vergel L Torres, Jianming Cao, Lijiang Chen, Jonathan J Wilksch, Richard A Strugnell, Trevor Lithgow, Tieli Zhou

Journal article  |  2017  |  Frontiers in Microbiology

A nanomechanical study of the effects of colistin on the Klebsiella pneumoniae AJ218 capsule

Anna Mularski, Jonathan Wilksch, Eric Hanssen, Jian Li, Takehiro Tomita, Sacha James Pidot, Tim Stinear, Frances Separovic, Dick Strugnell

Journal article  |  2017  |  European Biophysics Journal

Small RNA interactome of pathogenic E-coli revealed through crosslinking of RNase E

Shafagh A Waters, Sean P McAteer, Grzegorz Kudla, Ignatius Pang, Nandan P Deshpande, Timothy G Amos, Kai Wen Leong, Marc R Wilkins, Richard Strugnell, David L Gally, David Tollervey, Jai J Tree

Journal article  |  2017  |  The EMBO Journal

Influence of Fimbriae on Bacterial Adhesion and Viscoelasticity and Correlations of the Two Properties with Biofilm Formation

Huabin Wang, Jonathan J Wilksch, Ligang Chen, Jason WH Tan, Richard A Strugnell, Michelle L Gee

Journal article  |  2017  |  Langmuir

Mucosal-associated invariant T-cell activation and accumulation after in vivo infection depends on microbial riboflavin synthesis and co-stimulatory signals

Z Chen, H Wang, C D'Souza, S Sun, L Kostenko, SBG Eckle, BS Meehan, DC Jackson, RA Strugnell, H Cao, N Wang, DP Fairlie, L Liu, DI Godfrey, J Rossjohn, J McCluskey, AJ Corbett

Journal article  |  2017  |  Mucosal Immunology

Vaccine development: From concept to early clinical testing

Anthony L Cunningham, Nathalie Garcon, Oberdan Leo, Leonard R Friedland, Richard Strugnell, Beatrice Laupeze, Mark Doherty, Peter Stern

Journal article  |  2016  |  Vaccine

Vaccine provision: Delivering sustained & widespread use

Scott Preiss, Nathalie Garcon, Anthony L Cunningham, Richard Strugnell, Leonard R Friedland

Journal article  |  2016  |  Vaccine

Health at the Sub-catchment Scale: Typhoid and Its Environmental Determinants in Central Division, Fiji

Aaron Peter Jenkins, Stacy Jupiter, Ute Mueller, Adam Jenney, Gandercillar Vosaki, Varanisese Rosa, Alanieta Naucukidi, Kim Mulholland, Richard Strugnell, Mike Kama, Pierre Horwitz

Journal article  |  2016  |  EcoHealth

T cell help amplifies innate signals in CD8 DC for optimal CD8 T cell priming

M Greyer, PG Whitney, AT Stock, GM Davey, C Tebartz, A Bachem, JD Mintern, RA Strugnell, SJ Turner, T Gebhardt, M O'Keeffe, WR Heath, S Bedoui

Conference Proceedings  |  2016  |  EUROPEAN JOURNAL OF IMMUNOLOGY

Leptin and Il-17 mediated responses in vaccination against Helicobacter pylori

D Becher, J Ortega, S Raghavan, Sjokvist L Ottsjo, O Wijburg, RA Strugnell, A Walduck

Conference Proceedings  |  2016  |  EUROPEAN JOURNAL OF IMMUNOLOGY

Understanding antigen specificity of CD4( ) T cell responses in Salmonella infection is key to vaccine design

N Wang, RB Schittenhelm, AW Purcell, TA Scott, A Kupz, S Bedoui, RA Strugnell

Conference Proceedings  |  2016  |  EUROPEAN JOURNAL OF IMMUNOLOGY

Effective assembly of fimbriae in Escherichia coli depends on the translocation assembly module nanomachine

Christopher Stubenrauch, Matthew J Belousoff, Iain D Hay, Hsin-Hui Shen, James Lillington, Kellie L Tuck, Kate M Peters, Phan Minh-Duy, Alvin W Lo, Mark A Schembri, Richard A Strugnell, Gabriel Waksman, Trevor Lithgow

Journal article  |  2016  |  Nature Microbiology

Conserved Features in the Structure, Mechanism, and Biogenesis of the Inverse Autotransporter Protein Family

Eva Heinz, Christopher J Stubenrauch, Rhys Grinter, Nathan P Croft, Anthony W Purcell, Richard A Strugnell, Gordon Dougan, Trevor Lithgow

Journal article  |  2016  |  Genome Biology and Evolution

Atomic force microscopy of bacteria reveals the mechanobiology of pore forming peptide action

Anna Mularski, Jonathan J Wilksch, Eric Hanssen, Richard A Strugnell, Frances Separovic

Journal article  |  2016  |  Biochimica et Biophysica Acta (BBA) - Biomembranes

Curriculum design for research-led teaching: Molecule to Malady

Helen Cain, Richard Strugnell, Frederic Hollande

Journal article  |  2016  |  Microbiology Australia

Molecular Characterization of the Vacuolating Autotransporter Toxin in Uropathogenic Escherichia coli

Katie B Nichols, Makrina Totsika, Danilo G Moriel, Alvin W Lo, Ji Yang, Daniel J Wurpel, Amanda E Rossiter, Richard A Strugnell, Ian R Henderson, Glen C Ulett, Scott A Beatson, Mark A Schembri

Journal article  |  2016  |  Journal of Bacteriology

The intracellular pathway for the presentation of vitamin B-related antigens by the antigen-presenting molecule MR1

Hamish EG McWilliam, Sidonia BG Eckle, Alex Theodossis, Ligong Liu, Zhenjun Chen, Jacinta M Wubben, David P Fairlie, Richard A Strugnell, Justine D Mintern, James McCluskey, Jamie Rossjohn, Jose A Villadangos

Journal article  |  2016  |  Nature Immunology

Heat shock protein complex vaccines induce antibodies against Neisseria meningitidis via a MyD88-independent mechanism

Jia Xi Han, Garrett Z Ng, Paola Cecchini, Yok Teng Chionh, Muhammad A Saeed, Lisbeth M Naess, Michael Joachim, Lucy E Blandford, Richard A Strugnell, Camilo A Colaco, Philip Sutton

Journal article  |  2016  |  Vaccine

T Cell Help Amplifies Innate Signals in CD8( ) DCs for Optimal CD8( ) T Cell Priming

Marie Greyer, Paul G Whitney, Angus T Stock, Gayle M Davey, Christina Tebartz, Annabell Bachem, Justine D Mintern, Richard A Strugnell, Stephen J Turner, Thomas Gebhardt, Meredith O'Keeffe, William R Heath, Sammy Bedoui

Journal article  |  2016  |  Cell Reports

Interrogate the Antibacterial Activities of Nano Graphene Oxide Sheets

Huabin Wang, Jonathan J Wilksch, Richard A Strugnell, Haijun Yang

Conference Proceedings  |  2016  |  2016 IEEE International Conference on Manipulation, Manufacturing and Measurement on the Nanoscale (3M-NANO)

Successful treatment of biofilm infections using shock waves combined with antibiotic therapy

Divya Prakash Gnanadhas, Monalisha Elango, S Janardhanraj, CS Srinandan, Akshay Datey, Richard A Strugnell, Jagadeesh Gopalan, Dipshikha Chakravortty

Journal article  |  2015  |  Scientific Reports

Vaccination Method Affects Immune Response and Bacterial Growth but Not Protection in the Salmonella Typhimurium Animal Model of Typhoid

Clare L Kinnear, Richard A Strugnell

Journal article  |  2015  |  PLOS ONE

T-cell antigen formed from distinct metabolic pathways

Jeffrey Mak, Alexandra Corbett, Sidonia Eckle, Richard Birkinshaw, Ligong Liu, Onisha Patel, Jennifer Mahony, Zhenjun Chen, Rangsima Reantragoon, Bronwyn Meehan, Hanwei Cao, Nicholas Williamson, Richard Strugnell, Douwe Van Sinderen, David Fairlie, Lars Kjer-Nielsen, Jamie Rossjohn, James McCluskey

Conference Proceedings  |  2015  |  ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY

Conserved features in TamA enable interaction with TamB to drive the activity of the translocation and assembly module

Joel Selkrig, Matthew J Belousoff, Stephen J Headey, Eva Heinz, Takuya Shiota, Hsin-Hui Shen, Simone A Beckham, Rebecca S Bamert, Minh-Duy Phan, Mark A Schembri, Matthew CJ Wilce, Martin J Scanlon, Richard A Strugnell, Trevor Lithgow

Journal article  |  2015  |  Scientific Reports

Assembly of the secretion pores GspD, Wza and CsgG into bacterial outer membranes does not require the Omp85 proteins BamA or TamA

Rhys A Dunstan, Iain D Hay, Jonathan J Wilksch, Ralf B Schittenhelm, Anthony W Purcell, Joan Clark, Adam Costin, Georg Ramm, Richard A Strugnell, Trevor Lithgow

Journal article  |  2015  |  Molecular Microbiology

Genomic analysis of diversity, population structure, virulence, and antimicrobial resistance in Klebsiella pneumoniae, an urgent threat to public health

Kathryn E Holt, Heiman Wertheim, Ruth N Zadoks, Stephen Baker, Chris A Whitehouse, David Dance, Adam Jenney, Thomas R Connor, Li Yang Hsu, Juliette Severin, Sylvain Brisse, Hanwei Cao, Jonathan Wilksch, Claire Gorrie, Mark B Schultz, David J Edwards, Van Nguyen Kinh, Vu Nguyen Trung, Tuyet Dao Trinh, Martijn Mensinke, et al.

Journal article  |  2015  |  Proceedings of the National Academy of Sciences

Role of Capsular Polysaccharides in Biofilm Formation: An AFM Nanomechanics Study

Huabin Wang, Jonathan J Wilksch, Richard A Strugnell, Michelle L Gee

Journal article  |  2015  |  ACS Applied Materials and Interfaces

Atomic Force Microscopy Reveals the Mechanobiology of Lytic Peptide Action on Bacteria

Anna Mularski, Jonathan J Wilksch, Huabin Wang, Mohammed Akhter Hossain, John D Wade, Frances Separovic, Richard A Strugnell, Michelle L Gee

Journal article  |  2015  |  Langmuir

Positive Autoregulation of mrkHI by the Cyclic Di-GMP-Dependent MrkH Protein in the Biofilm Regulatory Circuit of Klebsiella pneumoniae

Jason WH Tan, Jonathan J Wilksch, Dianna M Hocking, Nancy Wang, Yogitha N Srikhanta, Marija Tauschek, Trevor Lithgow, Roy M Robins-Browne, Ji Yang, Richard A Strugnell

Journal article  |  2015  |  Journal of Bacteriology

Increased Autoimmune Diabetes in pIgR-Deficient NOD Mice Is Due to a "Hitchhiking" Interval that Refines the Genetic Effect of Idd5.4

Kim R Simpfendorfer, Richard A Strugnell, Thomas C Brodnicki, Odilia LC Wijburg

Journal article  |  2015  |  PLOS ONE

The Hd, Hj, and Hz66 flagella variants of Salmonella enterica serovar Typhi modify host responses and cellular interactions

Fernanda Schreiber, Sally Kay, Gad Frankel, Simon Clare, David Goulding, Esther van de Vosse, Jaap T van Dissel, Richard Strugnell, Guy Thwaites, Robert A Kingsley, Gordon Dougan, Stephen Baker

Journal article  |  2015  |  Scientific Reports

Cellular Requirements for Systemic Control of Salmonella enterica Serovar Typhimurium Infections in Mice

Andreas Kupz, Sammy Bedoui, Richard A Strugnell

Journal article  |  2014  |  Infection and Immunity

Leptin and IL-17 mediated responses in vaccination against Helicobacter pylori

Dorit Becher, Jacinta Ortega, Sukanya Raghavan, Louise Sjokvist Ottsjo, Odilia Wijburg, Richard Strugnell, Anna K Walduck

Conference Proceedings  |  2014  |  Cytokine

Congenic mice reveal genetic epistasis and overlapping disease loci for autoimmune diabetes and listeriosis

Nancy Wang, Colleen M Elso, Leanne Mackin, Stuart I Mannering, Richard A Strugnell, Odilia L Wijburg, Thomas C Brodnicki

Journal article  |  2014  |  Immunogenetics

Analysis of Salmonella enterica Serovar Typhimurium Variable-Number Tandem-Repeat Data for Public Health Investigation Based on Measured Mutation Rates and Whole-Genome Sequence Comparisons

Karolina Dimovski, Hanwei Cao, Odilia LC Wijburg, Richard A Strugnell, Radha K Mantena, Margaret Whipp, Geoff Hogg, Kathryn E Holt

Journal article  |  2014  |  Journal of Bacteriology

A mortise-tenon joint in the transmembrane domain modulates autotransporter assembly into bacterial outer membranes

Denisse L Leyton, Matthew D Johnson, Rajiv Thapa, Gerard HM Huysmans, Rhys A Dunstan, Nermin Celik, Hsin-Hui Shen, Dorothy Loo, Matthew J Belousoff, Anthony W Purcell, Ian R Henderson, Travis Beddoe, Jamie Rossjohn, Lisandra L Martin, Richard A Strugnell, Trevor Lithgow

Journal article  |  2014  |  Nature Communications

T-cell activation by transitory neo-antigens derived from distinct microbial pathways

Alexandra J Corbett, Sidonia BG Eckle, Richard W Birkinshaw, Ligong Liu, Onisha Patel, Jennifer Mahony, Zhenjun Chen, Rangsima Reantragoon, Bronwyn Meehan, Hanwei Cao, Nicholas A Williamson, Richard A Strugnell, Douwe Van Sinderen, Jeffrey YW Mak, David P Fairlie, Lars Kjer-Nielsen, Jamie Rossjohn, James McCluskey

Journal article  |  2014  |  Nature

In Vivo IFN-gamma Secretion by NK Cells in Response to Salmonella Typhimurium Requires NLRC4 Inflammasomes

Andreas Kupz, Roy Curtiss, Sammy Bedoui, Richard A Strugnell

Journal article  |  2014  |  PLoS One

F9 Fimbriae of Uropathogenic Escherichia coli Are Expressed at Low Temperature and Recognise Gal beta 1-3GlcNAc-Containing Glycans

Daniel J Wurpel, Makrina Totsika, Luke P Allsopp, Lauren E Hartley-Tassell, Christopher J Day, Kate M Peters, Sohinee Sarkar, Glen C Ulett, Ji Yang, Joe Tiralongo, Richard A Strugnell, Michael P Jennings, Mark A Schembri

Journal article  |  2014  |  PLoS ONE

NK cell intrinsic regulation of MIP-1 alpha by granzyme M

N Baschuk, N Wang, SV Watt, H Halse, C House, PI Bird, R Strugnell, JA Trapani, MJ Smyth, DM Andrews

Journal article  |  2014  |  Cell Death & Disease

Salmonella vaccines: lessons from the mouse model or bad teaching?

Richard A Strugnell, Timothy A Scott, Nancy Wang, Chenying Yang, Newton Peres, Sammy Bedoui, Andreas Kupz

Journal article  |  2014  |  Current Opinion in Microbiology

Emerging rules for effective antimicrobial coatings

Mario Salwiczek, Yue Qu, James Gardiner, Richard A Strugnell, Trevor Lithgow, Keith M McLean, Helmut Thissen

Journal article  |  2014  |  Trends in Biotechnology

Doctoral education as an element of cultural and economic prosperity: Nation building in the era of globalization

L Maheu, B Scholz, J Balán, JK Graybill, R Strugnell

Book Chapter  |  2014

Transcriptional Activation of the mrkA Promoter of the Klebsiella pneumoniae Type 3 Fimbrial Operon by the c-di-GMP-Dependent MrkH Protein

Ji Yang, Jonathan J Wilksch, Jason WH Tan, Dianna M Hocking, Chaille T Webb, Trevor Lithgow, Roy M Robins-Browne, Richard A Strugnell

Journal article  |  2013  |  PLoS One

Contribution of Secretory Antibodies to Intestinal Mucosal Immunity against Helicobacter pylori

Rebecca J Gorrell, Odilia LC Wijburg, John S Pedersen, Anna K Walduck, Terry Kwok, Richard A Strugnell, Roy M Robins-Browne

Journal article  |  2013  |  Infection and Immunity

Molecular basis for the increased polymyxin susceptibility of Klebsiella pneumoniae strains with under-acylated lipid A

Tony Velkov, Rachel L Soon, Pei L Chong, Johnny X Huang, Matthew A Cooper, Mohammad AK Azad, Mark A Baker, Philip E Thompson, Kade Roberts, Roger L Nation, Abigail Clements, Richard A Strugnell, Jian Li

Journal article  |  2013  |  Innate Immunity

Molecular basis for the increased polymyxin susceptibility ofKlebsiella pneumoniaestrains with under-acylated lipid A

Tony Velkov, Rachel L Soon, Pei L Chong, Johnny X Huang, Matthew A Cooper, Mohammad AK Azad, Mark A Baker, Philip E Thompson, Kade Roberts, Roger L Nation, Abigail Clements, Richard A Strugnell, Jian Li

Journal article  |  2013  |  Innate Immunity

Contribution of Thy1( ) NK cells to protective IFN-gamma production during Salmonella Typhimurium infections

Andreas Kupz, Timothy A Scott, Gabrielle T Belz, Daniel M Andrews, Marie Greyer, Andrew M Lew, Andrew G Brooks, Mark J Smyth, Roy Curtiss, Sammy Bedoui, Richard A Strugnell

Journal article  |  2013  |  Proceedings of the National Academy of Sciences of the United States of America

Systemic infection of Mice with Listeria monocytogenes to characterize host immune responses.

Nancy Wang, Richard A Strugnell, Odilia L Wijburg, Thomas C Brodnicki

Book Chapter  |  2013  |  Methods in Molecular Biology

Listeria monocytogenes is a Gram-positive facultative intracellular bacterium that is widely used to characterize bacterial pathog..

Nanomechanics measurements of live bacteria reveal a mechanism for bacterial cell protection: the polysaccharide capsule in Klebsiella is a responsive polymer hydrogel that adapts to osmotic stress

Huabin Wang, Jonathan J Wilksch, Trevor Lithgow, Richard A Strugnell, Michelle L Gee

Journal article  |  2013  |  Soft Matter

Assembly of the Type II Secretion System such as Found in Vibrio cholerae Depends on the Novel Pilotin AspS

Rhys A Dunstan, Eva Heinz, Lakshmi C Wijeyewickrema, Robert N Pike, Anthony W Purcell, Timothy J Evans, Judyta Praszkier, Roy M Robins-Browne, Richard A Strugnell, Konstantin V Korotkov, Trevor Lithgow

Journal article  |  2013  |  PLoS Pathogens

Salmonella Typhimurium's Transthyretin-Like Protein Is a Host-Specific Factor Important in Fecal Survival in Chickens

Sarah C Hennebry, Leanne C Sait, Raju Mantena, Thomas J Humphrey, Ji Yang, Timothy Scott, Andreas Kupz, Samantha J Richardson, Richard A Strugnell

Journal article  |  2012  |  PLoS One

A Bioinformatic Strategy for the Detection, Classification and Analysis of Bacterial Autotransporters

Nermin Celik, Chaille T Webb, Denisse L Leyton, Kathryn E Holt, Eva Heinz, Rebecca Gorrell, Terry Kwok, Thomas Naderer, Richard A Strugnell, Terence P Speed, Rohan D Teasdale, Vladimir A Likic, Trevor Lithgow

Journal article  |  2012  |  PLoS One

Discovery of an archetypal protein transport system in bacterial outer membranes

Joel Selkrig, Khedidja Mosbahi, Chaille T Webb, Matthew J Belousoff, Andrew J Perry, Timothy J Wells, Faye Morris, Denisse L Leyton, Makrina Totsika, Phan Minh-Duy, Nermin Celik, Michelle Kelly, Clare Oates, Elizabeth L Hartland, Roy M Robins-Browne, Sri Harsha Ramarathinam, Anthony W Purcell, Mark A Schembri, Richard A Strugnell, Ian R Henderson, et al.

Journal article  |  2012  |  Nature Structural and Molecular Biology

Chlamydia pneumoniae induces a pro-inflammatory phenotype in murine vascular smooth muscle cells independently of elevating reactive oxygen species

Jennifer Rivera, Anna K Walduck, Richard A Strugnell, Christopher G Sobey, Grant R Drummond

Journal article  |  2012  |  Clinical and Experimental Pharmacology and Physiology

NLRC4 inflammasomes in dendritic cells regulate noncognate effector function by memory CD8( ) T cells

Andreas Kupz, Greta Guarda, Thomas Gebhardt, Leif E Sander, Kirsty R Short, Dimitri A Diavatopoulos, Odilia LC Wijburg, Hanwei Cao, Jason C Waithman, Weisan Chen, Daniel Fernandez-Ruiz, Paul G Whitney, William R Heath, Roy Curtiss, Juerg Tschopp, Richard A Strugnell, Sammy Bedoui

Journal article  |  2012  |  Nature Immunology

Influenza Virus Induces Bacterial and Nonbacterial Otitis Media

Kirsty R Short, Dimitri A Diavatopoulos, Ruth Thornton, John Pedersen, Richard A Strugnell, Andrew K Wise, Patrick C Reading, Odilia L Wijburg

Journal article  |  2011  |  Journal of Infectious Diseases

Targeting of Neisserial PorB to the mitochondrial outer membrane: an insight on the evolution of beta-barrel protein assembly machines

Jhih-Hang Jiang, John K Davies, Trevor Lithgow, Richard A Strugnell, Kipros Gabriel

Journal article  |  2011  |  Molecular Microbiology

Measuring Bacterial Load and Immune Responses in Mice Infected with Listeria monocytogenes

Nancy Wang, Richard Strugnell, Odilia Wijburg, Thomas Brodnicki

Journal article  |  2011  |  Journal of Visualized Experiments

MrkH, a Novel c-di-GMP-Dependent Transcriptional Activator, Controls Klebsiella pneumoniae Biofilm Formation by Regulating Type 3 Fimbriae Expression

Jonathan J Wilksch, Ji Yang, Abigail Clements, Jacinta L Gabbe, Kirsty R Short, Hanwei Cao, Rosalia Cavaliere, Catherine E James, Cynthia B Whitchurch, Mark A Schembri, Mary LC Chuah, Zhao-Xun Liang, Odilia L Wijburg, Adam W Jenney, Trevor Lithgow, Richard A Strugnell

Journal article  |  2011  |  PLoS Pathogens

Vaccines of the future

LR Stanberry, R Strugnell

Journal article  |  2011  |  Perspectives in Vaccinology

Vaccine antigens

R Strugnell, F Zepp, A Cunningham, T Tantawichien

Journal article  |  2011  |  Perspectives in Vaccinology

NLRC4 inflammasomes in dendritic cells evoke non-cognate effector function by memory CD8 T cells that improve immunity to Salmonella typhimurium

Sammy Bedoui, Kupz Andreas, Greta Guarda, Thomas Gebhardt, Leif Sander, Roy Curtis, Jurg Tschopp, Richard Strugnell

Journal article  |  2011  |  JOURNAL OF IMMUNOLOGY

Using Bioluminescent Imaging to Investigate Synergism Between Streptococcus pneumoniae and Influenza A Virus in Infant Mice

Kirsty R Short, Dimitri A Diavatopoulos, Patrick C Reading, Lorena E Brown, Kelly L Rogers, Richard A Strugnell, Odilia LC Wijburg

Journal article  |  2011  |  Journal of Visualized Experiments

Local recall responses in the stomach involving reduced regulation and expanded help mediate vaccine-induced protection against Helicobacter pylori in mice

Dorit Becher, Michael E Deutscher, Kim R Simpfendorfer, Odilia L Wijburg, John S Pederson, Andrew M Lew, Richard A Strugnell, Anna K Walduck

Journal article  |  2010  |  European Journal of Immunology

The role of secretory antibodies in infection immunity

Richard A Strugnell, Odilia LC Wijburg

Journal article  |  2010  |  Nature Reviews Microbiology

The Microbiota Mediates Pathogen Clearance from the Gut Lumen after Non-Typhoidal Salmonella Diarrhea

Kathrin Endt, Baerbel Stecher, Samuel Chaffron, Emma Slack, Nicolas Tchitchek, Arndt Benecke, Laurye Van Maele, Jean-Claude Sirard, Andreas J Mueller, Mathias Heikenwalder, Andrew J Macpherson, Richard Strugnell, Christian von Mering, Wolf-Dietrich Hardt

Journal article  |  2010  |  PLoS Pathogens

Influenza A virus facilitates Streptococcus pneumoniae transmission and disease

Dimitri A Diavatopoulos, Kirsty R Short, John T Price, Jonathan J Wilksch, Lorena E Brown, David E Briles, Richard A Strugnell, Odilia L Wijburg

Journal article  |  2010  |  FASEB Journal

The Multi-Copper-Ion Oxidase CueO of Salmonella enterica Serovar Typhimurium Is Required for Systemic Virulence

Maud ES Achard, Jai J Tree, James A Holden, Kim R Simpfendorfer, Odilia LC Wijburg, Richard A Strugnell, Mark A Schembri, Matthew J Sweet, Michael P Jennings, Alastair G McEwan

Journal article  |  2010  |  Infection and Immunity

Different Bacterial Pathogens, Different Strategies, Yet the Aim Is the Same: Evasion of Intestinal Dendritic Cell Recognition

Sammy Bedoui, Andreas Kupz, Odilia L Wijburg, Anna K Walduck, Maria Rescigno, Richard A Strugnell

Journal article  |  2010  |  Journal of Immunology

The Microbiota Mediates Pathogen Clearance from the Gut Lumen after Non-Typhoidal Salmonella Diarrhea

K Endt, B Stecher, S Chaffron, E Slack, N Tchitchek, A Benecke, L Van Maele, J Sirard, A Mueller, M Heikenwalder, A Macpherson, R STRUGNELL, C von Mering, W Hardt

Journal article  |  2010  |  PLoS Pathogens

The reducible complexity of a mitochondrial molecular machine

Abigail Clements, Dejan Bursac, Xenia Gatsos, Andrew J Perry, Srgjan Civciristov, Nermin Celik, Vladimir A Likic, Sebastian Poggio, Christine Jacobs-Wagner, Richard A Strugnell, Trevor Lithgow

Journal article  |  2009  |  Proceedings of the National Academy of Sciences of the United States of America

Bacterial Antigen Expression Is an Important Component in Inducing an Immune Response to Orally Administered Salmonella-Delivered DNA Vaccines

Michelle E Gahan, Diane E Webster, Steven L Wesselingh, Richard A Strugnell, Ji Yang

Journal article  |  2009  |  PLoS One

Nanoscale study of the mechanical properties of individual and aggregated bacteria using atomic force microscopy

H WANG, JJ WILKSCH, R STRUGNELL, M GEE

Conference Proceedings  |  2009  |  8th World Congress of Chemical Engineering

CONSTRUCTION AND CHARACTERIZATION OF AN UNMARKED AROC DELETION MUTANT OF BURKHOLDERIA PSEUDOMALLEI STRAIN A2

Thitima Srilunchang, Tanakorn Proungvitaya, Surasak Wongratanacheewin, Richard Strugnell, Preecha Homchampa

Journal article  |  2009  |  Southeast Asian Journal of Tropical Medicine and Public Health

The Major Surface-Associated Saccharides of Klebsiella pneumoniae Contribute to Host Cell Association

Abigail Clements, Fabien Gaboriaud, Jerome FL Duval, Jacinta L Farn, Adam W Jenney, Trevor Lithgow, Odilia LC Wijburg, Elizabeth L Hartland, Richard A Strugnell

Journal article  |  2008  |  PLoS One

Impact of prior immunological exposure on vaccine delivery by Salmonella enterica serovar Typhimurium

Michelle E Gahan, Diane E Webster, Odilia LC Wijburg, Steven L Wesselingh, Richard A Strugnell

Journal article  |  2008  |  Vaccine

Poly-immunoglobulin Receptor-Mediated Transport of IgA into the Male Genital Tract is Important for Clearance of Chlamydia muridarum Infection

Kelly A Cunningham, Alison J Carey, Jane M Finnie, Shisan Bao, Charmere Coon, Russell Jones, Odilia Wijburg, Richard A Strugnell, Peter Timms, Kenneth W Beagley

Journal article  |  2008  |  American Journal of Reproductive Immunology

Targeting subcapsular antigens for prevention of Klebsiella pneumoniae infections

Abigail Clements, Adam W Jenney, Jacinta L Farn, Lorena E Brown, Georgia Deliyannis, Elizabeth L Hartland, Martin J Pearse, Margaret B Maloney, Steven L Wesselingh, Odilia L Wijburg, Richard A Strugnell

Journal article  |  2008  |  Vaccine

Coupled electrostatic, hydrodynamic, and mechanical properties of bacterial interfaces in aqueous media

Fabien Gaboriaud, Michelle L Gee, Richard Strugnell, Jerome FL Duval

Journal article  |  2008  |  Langmuir

Macrophages are mediators of gastritis in acute Helicobacter pylori infection in C57BL/6 mice

Maria Kaparakis, Anna K Walduck, Jason D Price, John S Pedersen, Nico Van Rooijen, Martin J Pearse, Odilia LC Wijburg, Richard A Strugnell

Journal article  |  2008  |  Infection and Immunity

Reactive oxygen species are the major antibacterials against Salmonella Typhimurium purine auxotrophs in the phagosome of RAW 264.7 cells

Radha KR Mantena, Odilia LC Wijburg, Christofer Vindurampulle, Vicki R Bennett-Wood, Anna Walduck, Grant R Drummond, John K Davies, Roy M Robins-Browne, Richard A Strugnell

Journal article  |  2008  |  Cellular Microbiology

Spatially resolved force spectroscopy of bacterial surfaces using force-volume imaging

Fabien Gaboriaud, Bhargava S Parcha, Michelle L Gee, James A Holden, Richard A Strugnell

Journal article  |  2008  |  Colloids and Surfaces B: Biointerfaces

Bicarbonate-mediated transcriptional activation of divergent operons by the virulence regulatory protein, RegA, from Citrobacter rodentium

Ji Yang, Emily Hart, Marija Tauschek, G Dean Price, Elizabeth L Hartland, Richard A Strugnell, Roy M Robins-Browne

Journal article  |  2008  |  Molecular Microbiology

CD8( ) T cells are associated with severe gastritis in Helicobacter pylori-infected mice in the absence of CD4( ) T cells

Mai Ping Tan, John Pedersen, Yifan Zhan, Andrew M Lew, Martin J Pearse, Odilia LC Wijburg, Richard A Strugnell

Journal article  |  2008  |  Infection and Immunity

Gamma interferon-independent effects of interleukin-12 on immunity to Salmonella enterica serovar typhimurium

Jason D Price, Kim R Simpfendorfer, Radhakrishnam R Mantena, James Holden, William R Heath, Nico van Rooijen, Richard A Strugnell, Odilia LC Wijburg

Journal article  |  2007  |  Infection and Immunity

Secondary acylation of Klebsiella pneumoniae lipopolysaccharide contributes to sensitivity to antibacterial peptides

Abigail Clements, Dedreia Tull, Adam W Jenney, Jacinta L Farn, Sang-Hyun Kim, Russell E Bishop, Joseph B McPhee, Robert EW Hancock, Elizabeth L Hartland, Martin J Pearse, Odilia LC Wijburg, David C Jackson, Malcolm J McConville, Richard A Strugnell

Journal article  |  2007  |  Journal of Biological Chemistry

Bacterial surface properties of Shewanella spp. as probed by force spectroscopy and microelectrophoresis

Etienne Daguel, Jerome FL Duval, Michelle L Gee, James A Holden, Richard Strugnell, Fabien Gaboriaud

Journal article  |  2007  |  ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY

Secretory antibodies reduce systemic antibody responses against the gastrointestinal commensal flora

Leanne C Sait, Maja Galic, Jason D Price, Kim R Simpfendorfer, Dimitri A Diavatopoulos, Tania K Uren, Peter H Janssen, Odilia LC Wijburg, Richard A Strugnell

Journal article  |  2007  |  International Immunology

Impact of plasmid stability on oral DNA delivery by Salmonella enterica serovar Typhimurium

Michelle E Gahan, Diane E Webster, Steven L Wesselingh, Richard A Strugnell

Journal article  |  2007  |  Vaccine

Chronic Helicobacter pylori infection does not significantly alter the microbiota of the murine stomach

Mai Ping Tan, Maria Kaparakis, Maja Galic, John Pedersen, Martin Pearse, Odilia LC Wijburg, Peter H Janssen, Richard A Strugnell

Journal article  |  2007  |  Applied and Environmental Microbiology

Transcriptional regulation of the yghJ-pppA-yghG-gspCDEFGHIJKLM cluster, encoding the type II secretion pathway in enterotoxigenic Escherichia coli

Ji Yang, Deborah L Baldi, Marija Tauschek, Richard A Strugnell, Roy M Robins-Browne

Journal article  |  2007  |  Journal of Bacteriology

Mechanisms of vaccine-induced protection against Helicobacter pylori

A Wehrens, T Aebischer, TF Meyer, D Becher, R Strugnell, A Walduck

Conference Proceedings  |  2006  |  HELICOBACTER

Specificity of CD4 T-cell response in murine Helicobacter pylori infections

M Tan, Z Chen, N La Gruta, OLC Wijburg, M Pearse, RA Strugnell

Conference Proceedings  |  2006  |  HELICOBACTER

Milk IgA responses are augmented by antigen delivery to the mucosal addressin cellular adhesion molecule 1

Susan Johnson, Dorothee Bourges, Odilia Wijburg, Richard A Strugnell, Andrew M Lew

Journal article  |  2006  |  Vaccine

CD4( ) CD25( ) regulatory T cells modulate the T-cell and antibody responses in Helicobacter-infected BALB/c mice

Maria Kaparakis, Karen L Laurie, Odilia Wijburg, John Pedersen, Martin Pearse, Ian R van Driel, Paul A Gleeson, Richard A Strugnell

Journal article  |  2006  |  Infection and Immunity

Antibody responses and epitope specificities to the Taenia solium cysticercosis vaccines TSOL18 and TSOL45-1A

CT Kyngdon, CG Gauci, AE Gonzalez, A Flisser, A Zoli, AJ Read, J Martinez-Ocana, RA Strugnell, MW Lightowlers

Journal article  |  2006  |  Parasite Immunology

Measles virus hemagglutinin protein expressed in transgenic lettuce induces neutralising antibodies in mice following mucosal vaccination

DE Webster, SD Smith, RJ Pickering, RA Strugnell, IB Dry, SL Wesselingh

Journal article  |  2006  |  Vaccine

In vitro oncosphere-killing assays to determine immunity to the larvae of Taenia pisiformis, Taenia ovis, Taenia saginata, and Taenia solium

CT Kyngdon, CG Gauci, RA Rolfe, JCV Guzman, MJF Salazar, MRV Pimentel, AE Gonzalez, HH Garcia, RH Gilman, RA Strugnell, MW Lightowlers

Journal article  |  2006  |  Journal of Parasitology

Innate secretory antibodies protect against natural Salmonella typhimurium infection

OLC Wijburg, TK Uren, K Simpfendorfer, FE Johansen, P Brandtzaeg, RA Strugnell

Journal article  |  2006  |  Journal of Experimental Medicine

Crude saponins improve the immune response to an oral plant-made measles vaccine

RJ Pickering, SD Smith, RA Strugnell, SL Wesselingh, DE Webster

Journal article  |  2006  |  Vaccine

Mucosal Immune Responses to Escherichia coli and Salmonella Infections.

Odilia LC Wijburg, Richard A Strugnell

Book Chapter  |  2006  |  EcoSal Plus

The best-characterized mucosa-associated lymphoid tissue (MALT), and also the most relevant for this review, is the gastrointestin..

Is mucosal IGA required to protect male mice against genital tract chlamydia infection?

K Cunningham, A Carey, D Hickey, R Jones, S Bao, R STRUGNELL, K Beagley

Conference Proceedings  |  2006  |  Chlamydial Infections

Seroepidemiology of Klebsiella pneumoniae in an Australian tertiary hospital and its implications for vaccine development

AW Jenney, A Clements, JL Farn, OL Wijburg, A McGlinchey, DW Spelman, TL Pitt, ME Kaufmann, L Liolios, MB Moloney, SL Wesselingh, RA Strugnell

Journal article  |  2006  |  Journal of Clinical Microbiology

Newer vaccines against typhoid fever and gastrointestinal salmonelloses

R STRUGNELL, O WIJBURG

Book Chapter  |  2006

Targeting the mammary gland for a local IgA response

S Johnson, D Bourges, O Wijburg, RA Strugnell, AM Lew

Conference Proceedings  |  2005  |  TISSUE ANTIGENS

Oral vaccine delivery by Salmonella Typhimurium

ME Gahan, DE Webster, SL Wesselingh, BB Finlay, RA Strugnell

Conference Proceedings  |  2005  |  TISSUE ANTIGENS

The role of IgA in protection against chlamydial infection of the male genital tract

KA Cunningham, AJ Carey, DK Hickey, A Russell, J Finnie, N Davies, S Bao, R Strugnell, KW Beagley

Conference Proceedings  |  2005  |  TISSUE ANTIGENS

The H-NS protein represses transcription of the eltAB operon, which encodes heat-labile enterotoxin in enterotoxigenic Escherichia coli, by binding to regions downstream of the promoter

J Yang, M Tauschek, R Strugnell, RM Robins-Browne

Journal article  |  2005  |  Microbiology-SGM

Salmonella enterica serovar typhimurium infection of dendritic cells leads to functionally increased expression of the macrophage-derived chemokine

G Fu, OLC Wijburg, PU Cameron, JD Price, RA Strugnell

Journal article  |  2005  |  Infection and Immunity

Vaccine-induced protection against gastrointestinal bacterial infections in the absence of secretory antibodies

TK Uren, OLC Wijburg, C Simmons, FE Johansen, P Brandtzaeg, RA Strugnell

Journal article  |  2005  |  European Journal of Immunology

Bypassing luminal barriers, delivery to a gut addressin by parenteral targeting elicits local IgA responses

BS McKenzie, AJ Corbett, S Johnson, JL Brady, J Pleasance, DR Kramer, JS Boyle, DC Jackson, RA Strugnell, AM Lew

Journal article  |  2004  |  International Immunology

Responses against complex antigens in various models of CD4 T-cell deficiency - Surprises from an anti-CD4 antibody transgenic mouse

YF Zhan, LE Brown, G Deliyannis, S Seah, OL Wijburg, J Price, RA Strugnell, PJ O'Connell, AM Lew

Journal article  |  2004  |  Immunol. Res.

Vaccines Against Alzheimer's Disease

RM ROBINS-BROWNE, RA STRUGNELL, CL MASTERS

Book Chapter  |  2004

Responses Against Complex Antigens in Various Models of CD4 T-Cell Deficiency

Y Zhan, LE BROWN, G DELIYANNIS, GKS SEAH, OL WIJBURG, JD PRICE, RA STRUGNELL, PJ O'Connell, AM LEW

Journal article  |  2004  |  Immunologic Research

Central role for B lymphocytes and CD4( ) T cells in immunity to infection by the attaching and effacing pathogen Citrobacter rodentium

CP Simmons, S Clare, M Ghaem-Maghami, TK Uren, J Rankin, A Huett, R Goldin, DJ Lewis, TT MacDonald, RA Strugnell, G Frankel, G Dougan

Journal article  |  2003  |  Infection and Immunity

In vitro and in vivo stability of recombinant plasmids in a vaccine strain of Salmonella enterica var. Typhimurium

SJ Dunstan, CP Simmons, RA Strugnell

Journal article  |  2003  |  FEMS Immunology and Medical Microbiology

Secretory antibodies do not affect the composition of the bacterial microbiota in the terminal ileum of 10-week-old mice

L Sait, M Galic, RA Strugnell, PH Janssen

Journal article  |  2003  |  Applied and Environmental Microbiology

Role of the polymeric Ig receptor in mucosal B cell homeostasis

TK Uren, FE Johansen, OLC Wijburg, F Koentgen, P Brandtzaeg, RA Strugnell

Journal article  |  2003  |  Journal of Immunology

Advances in Oral Vaccine Delivery Options

Diane E Webster, Michelle E Gahan, Richard A Strugnell, Steve L Wesselingh

Journal article  |  2003  |  American Journal of Drug Delivery

Induction of CD8( ) T lymphocytes by Salmonella typhimurium is independent of salmonella pathogenicity island 1-mediated host cell death

OLC Wijburg, N van Rooijen, RA Strugnell

Journal article  |  2002  |  Journal of Immunology

Successful boosting of a DNA measles immunization with an oral plant-derived measles virus vaccine

DE Webster, ML Cooney, ZJ Huang, DR Drew, IA Ramshaw, IB Dry, RA Strugnell, JL Martin, SL Wesselingh

Journal article  |  2002  |  Journal of Virology

Characterization and evidence of mobilization of the LEE pathogenicity island of rabbit-specific strains of enteropathogenic Escherichia coli

M Tauschek, RA Strugnell, RM Robins-Browne

Journal article  |  2002  |  Molecular Microbiology

Identification of a protein secretory pathway for the secretion of heat-labile enterotoxin by an enterotoxigenic strain of Escherichia coli

M Tauschek, RJ Gorrell, RA Strugnell, RM Robins-Browne

Journal article  |  2002  |  Proceedings of the National Academy of Sciences of the United States of America

Appetising solutions: an edible vaccine for measles

DE Webster, MC Thomas, RA Strugnell, IB Dry, SL Wesselingh

Journal article  |  2002  |  Medical Journal of Australia

A 320-kilobase artificial chromosome encoding the human HLA DR3-DQ2 MHC haplotype confers HLA restriction in transgenic mice

ZJ Chen, N Dudek, O Wijburg, R Strugnell, L Brown, G Deliyannis, D Jackson, F Koentgen, T Gordon, J McCluskey

Journal article  |  2002  |  Journal of Immunology

DNAExplorer

RA STRUGNELL, BC CRABB, CA GINNS, TS JUDD, J KIRK, CR CRAWFORD, A BONOLLO, GE KENNEDY, MJ KEPPELL

Software / Code  |  2002

Molecular characterization of a secreted enzyme with phospholipase B activity from Moraxella bovis

JL Farn, RA Strugnell, PA Hoyne, WP Michalski, JM Tennent

Journal article  |  2001  |  Journal of Bacteriology

The comparative efficacy of CTLA-4 and L-selectin targeted DNA vaccines in mice and sheep

DR Drew, JS Boyle, AM Lew, MW Lightowlers, PJ Chaplin, RA Strugnell

Journal article  |  2001  |  Vaccine

The human IgG3 hinge mediates the formation of antigen dimers that enhance humoral immune responses to DNA immunisation

DR Drew, JS Boyle, AM Lew, MW Lightowlers, RA Strugnell

Journal article  |  2001  |  Vaccine

Plant-derived measles virus hemagglutinin protein induces neutralizing antibodies in mice

Z Huang, I Dry, D Webster, R Strugnell, S Wesselingh

Journal article  |  2001  |  Vaccine

DNA Vaccination

RA STRUGNELL, DR DREW

Scholarly edition  |  2001

Nucleic acid vaccines - Tasks and tactics

BS McKenzie, AJ Corbett, JL Brady, CM Dyer, RA Strugnell, SJ Kent, DR Kramer, JS Boyle, AM Lew

Journal article  |  2001  |  Immunologic Research

DNAexplorer: Computer facilitated learning of bioinformatics using a situated model

GE KENNEDY, TS JUDD, MJ KEPPELL, CA GINNS, BS CRABB, RA STRUGNELL

Conference Proceedings  |  2001  |  Proceedings of ED-MEDIA 2001 world conference on educational multimedia, hypermedia and telecommunications

A comparison of DNA vaccines expressing the 45W, 18k and 16k host-protective antigens of Taenia ovis in mice and sheep

DR Drew, MW Lightowlers, RA Strugnell

Journal article  |  2000  |  Veterinary Immunology and Immunopathology

Humoral immune responses to DNA vaccines expressing secreted, membrane bound and non-secreted forms of the Taenia ovis 45W antigen

DR Drew, M Lightowlers, RA Strugnell

Journal article  |  2000  |  Vaccine

Kinetics of the mucosal antibody secreting cell response and evidence of specific lymphocyte migration to the lung after oral immunisation with attenuated S-enterica var. typhimurium

JS Allen, G Dougan, RA Strugnell

Journal article  |  2000  |  FEMS Immunology & Medical Microbiology

Dual role for macrophages in vivo in pathogenesis and control of murine Salmonella enterica var. Typhimurium infections

OLC Wijburg, CP Simmons, N van Rooijen, RA Strugnell

Journal article  |  2000  |  European Journal of Immunology

Dual role for macrophages in vivo in pathogenesis and control of murine Salmonella enterica var. Typhimurium infections.

OL Wijburg, CP Simmons, N van Rooijen, RA Strugnell

Journal article  |  2000  |  European Journal of Immunology

Salmonella spp. are regarded as facultative intracellular bacterial pathogens which are found inside macrophages (Mphi) after i. v..

A novel member of the NK-lysin protein family is developmentally regulated and secreted by Fasciola hepatica

MB Reed, RA Strugnell, M Panaccio, TW Spithill

Journal article  |  2000  |  Molecular and Biochemical Parasitology

Vaccination with plasmid DNA expressing antigen from genomic or cDNA gene forms induces equivalent humoral immune responses

DR Drew, M Lightowlers, RA Strugnell

Journal article  |  1999  |  Vaccine

Genetic vaccination strategies for enhanced cellular, humoral and mucosal immunity

AJ Ramsay, SJ Kent, RA Strugnell, A Suhrbier, SA Thomson, IA Ramshaw

Journal article  |  1999  |  Immunological Reviews

Use of in vivo-regulated promoters to deliver antigens from attenuated Salmonella enterica var. typhimurium

SJ Dunstan, CP Simmons, RA Strugnell

Journal article  |  1999  |  Infection and Immunity

Humoral responses in mice following vaccination with DNA encoding glutathione S-transferase of Fasciola hepatica: effects of mode of vaccination and the cellular compartment of antigen expression

PM Smooker, KR Steeper, DR Drew, RA Strugnell, TW Spithill

Journal article  |  1999  |  Parasite Immunology

Developmental expression of a Fasciola hepatica sequence homologous to ABC transporters

MB Reed, M Panaccio, RA Strugnell, TW Spithill

Journal article  |  1998  |  International Journal for Parasitology

Intranasal immunization with yeast-expressed 19 kD carboxyl-terminal fragment of Plasmodium yoelii merozoite surface protein-1 (yMSP1(19)) induces protective immunity to blood stage malaria infection in mice

C Hirunpetcharat, D Stanisic, XQ Liu, J Vadolas, RA Strugnell, R Lee, LH Miller, DC Kaslow, MF Good

Journal article  |  1998  |  Parasite Immunology

Identification and sequencing of the groE operon and flanking genes of Lawsonia intracellularis: use in phylogeny

CJH Dale, EK Moses, CC Ong, CJ Morrow, MB Reed, D Hasse, RA Strugnell

Journal article  |  1998  |  Microbiology

Fasciola hepatica: Stage-specific expression of novel gene sequences as identified by differential display

MB Reed, TW Spithill, RA Strugnell, M Panaccio

Journal article  |  1998  |  Experimental Parasitology

Bacterial vectors: why have they failed to deliver

R Strugnell, C Simmons, O Wijburg, T Uren, D Drew, S Dunstan

Journal article  |  1998  |  Australasian Biotechnology

The role of macrophages in the induction and regulation of immunity elicited by exogenous antigens

OLC Wijburg, GPJM van den Dobbelsteen, J Vadolas, A Sanders, RA Strugnell, N van Rooijen

Journal article  |  1998  |  European Journal of Immunology

Vaccine potential of attenuated mutants of Corynebacterium pseudotuberculosis in sheep

CP Simmons, SJ Dunstan, M Tachedjian, J Krywult, ALM Hodgson, RA Strugnell

Journal article  |  1998  |  Infection and Immunity

Comparison of the abilities of different attenuated Salmonella typhimurium strains to elicit humoral immune responses against a heterologous antigen

SJ Dunstan, CP Simmons, RA Strugnell

Journal article  |  1998  |  Infection and Immunity

Studies of the pathogenesis and immunology of attenuated mutants of Salmonella enterica var. Typhimurium: Lessons for human typhoid fever?

SJ Dunstan, CP Simmons, OLC Wijburg, TK Uren, N van Rooijen, RA Strugnell

Journal article  |  1998  |  Medical Journal of Indonesia

Development of recombinant S. Typhimurium, as a model for S. Typhi-based vaccine vectors

SJ Dunstan, CP Simmons, RA Strugnell

Journal article  |  1998  |  Medical Journal of Indonesia

Alveolar macrophages regulate the induction of primary cytotoxic T-lymphocyte responses during influenza virus infection

OLC Wijburg, S DiNatale, J Vadolas, N vanRooijen, RA Strugnell

Journal article  |  1997  |  Journal of virology

Identification and characterization of a K88- and CS31A-like operon of a rabbit enteropathogenic Escherichia coli strain which encodes fimbriae involved in the colonization of rabbit intestine

LM Adams, CP Simmons, L Rezmann, RA Strugnell, RM RobinsBrowne

Journal article  |  1997  |  Infection and immunity

The sacB gene cannot be used as a counter-selectable marker in Pasteurella multocida

BH Jost, P Homchampa, RA Strugnell, B Adler

Journal article  |  1997  |  Molecular Biotechnology

DNA vaccines for bacterial infections

RA Strugnell, D Drew, J Mercieca, S DiNatale, N Firez, SJ Dunstan, CP Simmons, J Vadolas

Journal article  |  1997  |  Immunology and Cell Biology

Attenuation and vaccine potential of aroQ mutants of Corynebacterium pseudotuberculosis

CP Simmons, ALM Hodgson, RA Strugnell

Journal article  |  1997  |  Infection and immunity

Cross protective immunity conferred by a marker free aroA mutant of Pasteurella multocida

P Homchampa, RA Strugnell, B Adler

Journal article  |  1997  |  Vaccine

Nucleic acid vaccination of sheep: Use in combination with a conventional adjuvanted vaccine against Taenia ovis

JS Rothel, JG Waterkeyn, RA Strugnell, PR Wood, HF Seow, J Vadolas, MW Lightowlers

Journal article  |  1997  |  Immunology and Cell Biology

Characterization of a Pasteurella multocida plasmid and its use to express recombinant proteins in P-multocida

CL Wright, RA Strugnell, ALM Hodgson

Journal article  |  1997  |  Plasmid

Cloning and manipulation of the Corynebacterium pseudotuberculosis recA gene for live vaccine vector development

CA Pogson, CP Simmons, RA Strugnell, ALM Hodgson

Journal article  |  1996  |  FEMS Microbiology Letters

Eukaryotic expression of recombinant biglycan - Post-translational processing and the importance of secondary structure for biological activity

AM Hocking, RA Strugnell, P Ramamurthy, DJ McQuillan

Journal article  |  1996  |  Journal of Biological Chemistry

Studies of immunity and bacterial invasiveness in mice given a recombinant Salmonella vector encoding murine interleukin-6

SJ Dunstan, AJ Ramsay, RA Strugnell

Journal article  |  1996  |  Infection and immunity

Immunity and vaccine development in Pasteurella multocida infections

B Adler, R Chancellor, P Homchampa, M Hunt, C Ruffolo, R Strugnell, D Wapling

Conference Proceedings  |  1996  |  Journal of Biotechnology

Cytokine gene knockout mice - Lessons for mucosal B-cell development

AJ Ramsay, SS Bao, KW Beagley, SJ Dunstan, AJ Husband, M Kopf, KI Matthaei, IA Ramshaw, RA Strugnell, IG Young, XY Tan

Book Chapter  |  1996

SALMONELLA-TYPHIMURIUM DISPLAYS NORMAL INVASION OF MICE WITH DEFECTIVE EPIDERMAL GROWTH-FACTOR RECEPTORS

A MCNEIL, SJ DUNSTAN, S CLARK, RA STRUGNELL

Journal article  |  1995  |  Infection and immunity

INTRANASAL IMMUNIZATION WITH LIPOSOMES INDUCES STRONG MUCOSAL IMMUNE-RESPONSES IN MICE

J VADOLAS, JK DAVIES, PJ WRIGHT, RA STRUGNELL

Journal article  |  1995  |  European Journal of Immunology

ANTIBODY REACTIVITY TO MYCOBACTERIAL 65-KDA HEAT-SHOCK PROTEIN - RELEVANCE TO AUTOIMMUNITY

C KAROPOULOS, MJ ROWLEY, CJ HANDLEY, RA STRUGNELL

Journal article  |  1995  |  Journal of Autoimmunity

CONSTRUCTION AND VACCINE POTENTIAL OF AN AROA MUTANT OF PASTEURELLA-HAEMOLYTICA

P HOMCHAMPA, RA STRUGNELL, B ADLER

Journal article  |  1994  |  Veterinary Microbiology

SALMONELLA-TYPHIMURIUM DELTA-AROA DELTA-AROD MUTANTS EXPRESSING A FOREIGN RECOMBINANT PROTEIN INDUCE SPECIFIC MAJOR HISTOCOMPATIBILITY COMPLEX CLASS I-RESTRICTED CYTOTOXIC T-LYMPHOCYTES IN MICE

SJ TURNER, FR CARBONE, RA STRUGNELL

Journal article  |  1993  |  Infection and Immunity

NEISSERIA-GONORRHOEAE STRAIN-MS11 HARBORING A MUTATION IN GENE AROA IS ATTENUATED AND IMMUNOGENIC

LM CHAMBERLAIN, R STRUGNELL, G DOUGAN, CE HORMAECHE, RD DEHORMAECHE

Journal article  |  1993  |  Microbial Pathogenesis

CONTROL OF GONOCOCCAL PILIN-ENCODING GENE-EXPRESSION IN ESCHERICHIA-COLI

JAM FYFE, RA STRUGNELL, JK DAVIES

Journal article  |  1993  |  Gene

Immunization Against Bordetella pertussis Infection of Mice Using a Salmonella typhimurium aro Vaccine Strain Expressing the Bordetella pertussis P.69 Antigen

M Roberts, G Dougan, JL Li, S Chatfield, R Strugnell

Journal article  |  1993  |  Biologicals

MOLECULAR ANALYSIS OF THE AROA GENE OF PASTEURELLA-MULTOCIDA AND VACCINE POTENTIAL OF A CONSTRUCTED AROA MUTANT

P HOMCHAMPA, RA STRUGNELL, B ADLER

Journal article  |  1992  |  Molecular Microbiology

MOLECULAR CHARACTERIZATION OF A GENOMIC REGION ASSOCIATED WITH VIRULENCE IN DICHELOBACTER-NODOSUS

ME KATZ, RA STRUGNELL, JI ROOD

Journal article  |  1992  |  Infection and Immunity

CHARACTERIZATION OF A SALMONELLA-TYPHIMURIUM-ARO VACCINE STRAIN EXPRESSING THE P.69 ANTIGEN OF BORDETELLA-PERTUSSIS

R STRUGNELL, G DOUGAN, S CHATFIELD, I CHARLES, N FAIRWEATHER, J TITE, JL LI, J BEESLEY, M ROBERTS

Journal article  |  1992  |  Infection and Immunity

CONSTRUCTION OF A GENETICALLY DEFINED SALMONELLA-TYPHI TY2 AROA, AROC MUTANT FOR THE ENGINEERING OF A CANDIDATE ORAL TYPHOID TETANUS VACCINE

SN CHATFIELD, N FAIRWEATHER, I CHARLES, D PICKARD, M LEVINE, D HONE, M POSADA, RA STRUGNELL, G DOUGAN

Journal article  |  1992  |  Vaccine

Rationally attenuated pathogens as vaccines and antigen carriers

R Strugnell, M Roberts, G Dougan

Journal article  |  1990  |  Today's Life Science

USE OF LIVE ATTENUATED BACTERIA TO STIMULATE IMMUNITY

NF FAIRWEATHER, SN CHATFIELD, IG CHARLES, M ROBERTS, M LIPSCOMBE, LJ LI, D STRUGNELL, S COMERFORD, J TITE, G DOUGAN

Journal article  |  1990  |  Research in Microbiology

ORAL VACCINATION OF MICE AGAINST TETANUS BY USE OF A LIVE ATTENUATED SALMONELLA CARRIER

NF FAIRWEATHER, SN CHATFIELD, AJ MAKOFF, RA STRUGNELL, J BESTER, DJ MASKELL, G DOUGAN

Journal article  |  1990  |  Infection and Immunity

STABLE EXPRESSION OF FOREIGN ANTIGENS FROM THE CHROMOSOME OF SALMONELLA-TYPHIMURIUM VACCINE STRAINS

RA STRUGNELL, D MASKELL, N FAIRWEATHER, D PICKARD, A COCKAYNE, C PENN, G DOUGAN

Journal article  |  1990  |  Gene

USE OF THE POLYMERASE CHAIN-REACTION TO DETECT DNA-SEQUENCES SPECIFIC TO PATHOGENIC TREPONEMES IN CEREBROSPINAL-FLUID

PE HAY, JR CLARKE, RA STRUGNELL, D TAYLORROBINSON, D GOLDMEIER

Journal article  |  1990  |  FEMS Microbiology Letters

MOLECULAR AND ANTIGENIC ANALYSIS OF TREPONEMES

R STRUGNELL, A COCKAYNE, CW PENN

Journal article  |  1990  |  Critical Reviews in Microbiology

LIVE SALMONELLA AS VACCINES AND CARRIERS OF FOREIGN ANTIGENIC DETERMINANTS

SN CHATFIELD, RA STRUGNELL, G DOUGAN

Journal article  |  1989  |  Vaccine

ANTIGENIC AND STRUCTURAL-ANALYSIS OF TREPONEMA-DENTICOLA

A COCKAYNE, R SANGER, A IVIC, RA STRUGNELL, JH MACDOUGALL, RRB RUSSELL, CW PENN

Journal article  |  1989  |  Microbiology

CLONING AND EXPRESSION OF TREPONEMA-PALLIDUM ANTIGENS IN ESCHERICHIA-COLI

MJ BAILEY, CM THOMAS, A COCKAYNE, RA STRUGNELL, CW PENN

Journal article  |  1989  |  Microbiology

COMPARATIVE ANTIGENIC ANALYSIS OF TREPONEMA-PALLIDUM LABORATORY AND STREET STRAINS

A COCKAYNE, RA STRUGNELL, MJ BAILEY, CW PENN

Journal article  |  1989  |  Microbiology

EXPERIMENTAL SYPHILITIC ORCHITIS - RELATIONSHIP BETWEEN TREPONEMA-PALLIDUM INFECTION AND TESTIS SYNTHESIS OF PROTEOGLYCANS

RA STRUGNELL, T KENT, CJ HANDLEY, S FAINE

Journal article  |  1988  |  American Journal of Pathology

PROTEINS THAT APPEAR TO BE ASSOCIATED WITH PILI IN NEISSERIA-GONORRHOEAE

LL MUIR, RA STRUGNELL, JK DAVIES

Journal article  |  1988  |  Infection and Immunity

CHARACTERIZATION OF THE PROTEOGLYCANS SYNTHESIZED BY RABBIT TESTIS IN RESPONSE TO INFECTION BY TREPONEMA-PALLIDUM

RA STRUGNELL, CJ HANDLEY, LP DRUMMOND, S FAINE

Journal article  |  1986  |  American Journal of Pathology

DEVELOPMENT OF INCREASED SERUM IMMUNOBLOT REACTIVITY AGAINST A 45,000-DALTON POLYPEPTIDE OF TREPONEMA-PALLIDUM (NICHOLS) CORRELATES WITH ESTABLISHMENT OF CHANCRE IMMUNITY IN SYPHILITIC RABBITS

RA STRUGNELL, WF WILLIAMS, L DRUMMOND, JS PEDERSEN, BH TOH, S FAINE

Journal article  |  1986  |  Infection and Immunity

SECONDARY LESIONS IN RABBITS EXPERIMENTALLY INFECTED WITH TREPONEMA-PALLIDUM

RA STRUGNELL, L DRUMMOND, S FAINE

Journal article  |  1986  |  Sexually Transmitted Infections

AUTOANTIBODIES TO CREATINE-KINASE IN RABBITS INFECTED WITH TREPONEMA-PALLIDUM

RA STRUGNELL, WF WILLIAMS, G RAINES, JS PEDERSEN, LP DRUMMOND, BH TOH, S FAINE

Journal article  |  1986  |  Journal of Immunology

Polyanions in syphilis: evidence that glycoproteins and macromolecules resembling glycosaminoglycans are synthesised by host tissues in response to infection with Treponema pallidum.

RA Strugnell, CJ Handley, L Drummond, S Faine, DA Lowther, SR Graves

Journal article  |  1984  |  Sexually Transmitted Infections

We investigated by means of radiolabelled precursors the source and nature of the polyanionic macromolecules present in rabbit tis..

IMMUNIZATION OF RABBITS WITH SPIROCHAETA-AURANTIA DOES NOT INDUCE RESISTANCE TO TREPONEMA-PALLIDUM

S GRAVES, L DRUMMOND, R STRUGNELL

Journal article  |  1984  |  Sexually Transmitted Diseases

Inhibitory effect of syphilitic rabbit serum on DNA synthesis in rabbit cells in vitro

GHW Wong, B Steiner, R Strugnell

Journal article  |  1984  |  British Journal of Venereal Diseases

INHIBITORY EFFECT OF SYPHILITIC RABBIT SERUM ON DNA-SYNTHESIS IN RABBIT-CELLS INVITRO

GHW WONG, B STEINER, R STRUGNELL, S FAINE, S GRAVES

Journal article  |  1984  |  Sexually Transmitted Infections

TREPONEMA-PALLIDUM DOES NOT SYNTHESIZE INVITRO A CAPSULE CONTAINING GLYCOSAMINOGLYCANS OR PROTEOGLYCANS

RA STRUGNELL, CJ HANDLEY, DA LOWTHER, S FAINE, SR GRAVES

Journal article  |  1984  |  Sexually Transmitted Infections

RESPONSE OF SYPHILITIC RABBITS TO REINFECTION WITH HOMOLOGOUS AND HETEROLOGOUS TREPONEMA-PALLIDUM STRAINS

RA STRUGNELL, S FAINE, S GRAVES

Journal article  |  1984  |  Infection and Immunity

A MONOCLONAL IGM SMOOTH-MUSCLE ANTIBODY REACTIVE WITH FIBROBLAST STRESS FIBERS PRODUCED BY IMMUNIZATION WITH TREPONEMA-PALLIDUM

RA STRUGNELL, JR UNDERWOOD, FM CLARKE, JS PEDERSEN, PJ CHALMERS, S FAINE, BH TOH

Journal article  |  1983  |  Clinical and Experimental Immunology

ORIGINAL ARTICLE: Poly-Immunoglobulin Receptor-Mediated Transport of IgA into the Male Genital Tract is Important for Clearance of Chlamydia muridarum Infection

Kelly A Cunningham, Alison J Carey, Jane M Finnie, Shisan Bao, Charmere Coon, Russell Jones, Odilia Wijburg, Richard A Strugnell, Peter Timms, Kenneth W Beagley

Journal article  |  American Journal of Reproductive Immunology