Marlene Hao

Group I Metabotropic Glutamate Receptors Modulate Motility and Enteric Neural Activity in the Mouse Colon

Anita JL Leembruggen, Yuqing Lu, Haozhe Wang, Volkan Uzungil, Thibault Renoir, Anthony JJ Hannan, Lincon AA Stamp, Marlene MM Hao, Joel CC Bornstein

Journal article  |  2023  |  BIOMOLECULES

Glutamate is the major excitatory neurotransmitter in the central nervous system, and there is evidence that Group-I metabotropic ..

The many means of conversation between the brain and the gut

Marlene M Hao, Lincon A Stamp

Journal article  |  2022  |  NATURE REVIEWS GASTROENTEROLOGY & HEPATOLOGY

Simultaneous whole-cell patch-clamp and calcium imaging on myenteric neurons.

Zhiling Li, Werend Boesmans, Youcef Kazwiny, Marlene M Hao, Pieter Vanden Berghe

Journal article  |  2022  |  Am J Physiol Gastrointest Liver Physiol

Live calcium imaging is often used as a proxy for electrophysiological measurements and has been a valuable tool that allows simul..

A Novel Method for Identifying the Transition Zone in Long-Segment Hirschsprung Disease: Investigating the Muscle Unit to Ganglion Ratio

Wendy Yang, Jenny Pham, Sebastian K King, Donald F Newgreen, Heather M Young, Lincon A Stamp, Marlene M Hao

Journal article  |  2022  |  BIOMOLECULES

Hirschsprung disease (HSCR) is characterised by the absence of enteric ganglia along variable lengths of the distal bowel. Current..

Enteric glial cells favor accumulation of anti-inflammatory macrophages during the resolution of muscularis inflammation.

Michelle Stakenborg, Saeed Abdurahiman, Veronica De Simone, Gera Goverse, Nathalie Stakenborg, Lies van Baarle, Qin Wu, Dimitri Pirottin, Jung-Seok Kim, Louise Chappell-Maor, Isabel Pintelon, Sofie Thys, Emilie Pollenus, Louis Boon, Philippe Van den Steen, Marlene Hao, Jo A Van Ginderachter, Guy E Boeckxstaens, Jean-Pierre Timmermans, Steffen Jung, et al.

Journal article  |  2022  |  Mucosal Immunol

Monocyte-derived macrophages (Mφs) are crucial regulators during muscularis inflammation. However, it is unclear which micro-envir..

Development, Diversity, and Neurogenic Capacity of Enteric Glia

Werend Boesmans, Amelia Nash, Kinga R Tasnady, Wendy Yang, Lincon A Stamp, Marlene M Hao

Journal article  |  2022  |  FRONTIERS IN CELL AND DEVELOPMENTAL BIOLOGY

Enteric glia are a fascinating population of cells. Initially identified in the gut wall as the "support" cells of the enteric ner..

Surgical method to prevent early death of neonatal rat pups with Hirschsprung disease, thus permitting development of long-term therapeutic approaches

Lincon A Stamp, Enie Lei, Jamie JM Liew, Ruslan Pustovit, Marlene M Hao, David H Croaker, John B Furness, Cameron D Adams

Journal article  |  2022  |  BIOLOGY METHODS & PROTOCOLS

Hirschsprung disease occurs when children are born with no intrinsic nerve cells in varying lengths of the large intestine. In the..

Circadian Control of Gastrointestinal Motility.

Anita JL Leembruggen, Lincon A Stamp, Joel C Bornstein, Marlene M Hao

Book Chapter  |  2022  |  Advances in Experimental Medicine and Biology

With the earth's 24-h rotation cycle, physiological function fluctuates in both diurnal and nocturnal animals, thereby ensuring op..

Upper Gastrointestinal Motility, Disease and Potential of Stem Cell Therapy.

Jesse Gardner-Russell, Jakob Kuriakose, Marlene M Hao, Lincon A Stamp

Book Chapter  |  2022  |  Advances in Experimental Medicine and Biology

Many gastrointestinal motility disorders arise due to defects in the enteric nervous system. Achalasia and gastroparesis are two e..

The role of the circadian rhythm on enteric neural plasticity and gut motility

Anita JL Leembruggen, Lincon A Stamp, Joel C Bornstein, Marlene M Hao

Conference Proceedings  |  2020  |  NEUROGASTROENTEROLOGY AND MOTILITY