Rob Ramsay

Re-do cytoreductive surgery for peritoneal surface malignancy: Is it worthwhile?

Vignesh Narasimhan, Francis Cheung, Peadar Waters, Oliver Peacock, Satish Warrier, Craig Lynch, Michael Michael, Robert Ramsay, Alexander Heriot

Journal article  |  2019  |  The Surgeon

BACKGROUND AND OBJECTIVES: Cytoreductive surgery (CRS) with hyperthermic intraperitoneal chemotherapy (HIPEC) offers selected pati..

First-in-human phase I clinical trial of a combined immune modulatory approach using TetMYB vaccine and Anti-PD-1 antibody in patients with advanced solid cancer including colorectal or adenoid cystic carcinoma: The MYPHISMO study protocol (NCT03287427).

Toan Pham, Lloyd Pereira, Sara Roth, Laura Galletta, Emma Link, Tim Akhurst, Ben Solomon, Michael Michael, Phillip Darcy, Shienny Sampurno, Alexander Heriot, Robert Ramsay, Jayesh Desai

Journal article  |  2019  |  Contemporary Clinical Trials Communications

Background: MYB is a transcription factor that is overexpressed in colorectal cancer (CRC) and also a driver mutation in adenoid c..

Perceptions in the management of colorectal peritoneal metastases: A bi-national survey of colorectal surgeons

Vignesh Narasimhan, Satish Warrier, Michael Michael, Jacob J McCormick, Robert Ramsay, Craig Lynch, Alexander Heriot

Journal article  |  2019  |  Pleura and Peritoneum

Background: There is great variability in the uptake of cytoreductive surgery (CRS) with hyperthermic intraperitoneal chemotherapy..

Modeling open surgery in mice to explore peritoneal damage, carbon dioxide humidification and desmoidogenesis

Timothy Chittleborough, Shienny Sampurno, Sandra Carpinteri, Andrew Craig Lynch, Alexander Graham Heriot, Robert George Ramsay

Journal article  |  2019  |  Pleura and Peritoneum

Abstract Background The exposure of the peritoneum to desiccation during surgery generates lasting damage to the mesothelial lini..

Oxaliplatin versus Mitomycin C following complete cytoreduction for colorectal peritoneal metastases: a comparative study.

Vignesh Narasimhan, Satish Warrier, Michael Michael, Robert Ramsay, Alexander Heriot

Journal article  |  2019  |  Journal of Gastrointestinal Surgery

BACKGROUND AND OBJECTIVES: Cytoreductive surgery (CRS) with hyperthermic intraperitoneal chemotherapy (HIPEC) can offer selected p..

Modes of carbon dioxide delivery during laparoscopy generate distinct differences in peritoneal damage and hypoxia in a porcine model

Shienny Sampurno, Timothy J Chittleborough, Sandra Carpinteri, Jonathan Hiller, Alexander Heriot, Andrew Craig Lynch, Robert George Ramsay

Journal article  |  2019  |  Surgical Endoscopy

BACKGROUND: Insufflation with CO2 can employ continuous flow, recirculated gas and/or additional warming and humidification. The a..

Evolution of Cytoreductive Surgery and Hyperthermic Intraperitoneal Chemotherapy for Colorectal Peritoneal Metastases: 8-Year Single-Institutional Experience

Vignesh Narasimhan, Maneka Britto, Pham Toan, Satish Warrier, Arun Naik, A Craig Lynch, Michael Michael, Jeanne Tie, Robert Ramsay, Alexander Heriot

Journal article  |  2019  |  Diseases of the Colon & Rectum

BACKGROUND: Colorectal cancer is the second leading cause of cancer-related mortality worldwide. Peritoneal metastases carry the w..

Antagonism of IAPs enhances CAR T cell efficacy

J Michie, PA Beavis, AJ Freeman, SJ Vervoort, KM Ramsbottom, V Narasimhan, EJ Lelliott, N Lalaoui, RG Ramsay, RW Johnstone, J Silke, PK Darcy, I Voskoboinik, CJ Kearney, J Oliaro

Conference Proceedings  |  2019  |  EUROPEAN JOURNAL OF IMMUNOLOGY

Organoids: the new kid in cancer research

Vignesh Narasimhan, Atandrila Das, Pham Toan, Kasmira Wilson, Joseph Kong, Robert Ramsay, Alexander Heriot

Journal article  |  2019  |  ANZ Journal of Surgery

Precision medicine in colorectal surgery: coming to a hospital near you

Kasmira Wilson, Vignesh Narasimhan, Toan Pham, Atandrila Das, Robert Ramsay, Alexander Heriot

Journal article  |  2019  |  ANZ Journal of Surgery

Colorectal peritoneal metastases: still a nihilistic outlook?

Vignesh Narasimhan, Toan Pham, Robert Ramsay, Alexander Heriot, Satish Warrier

Journal article  |  2019  |  ANZ Journal of Surgery

Outcomes from cytoreduction and hyperthermic intraperitoneal chemotherapy for appendiceal epithelial neoplasms

Vignesh Narasimhan, Pham Toan, Satish Warrier, A Craig Lynch, Michael Michael, Jeanne Tie, Robert Ramsay, Alexander Heriot

Journal article  |  2019  |  ANZ Journal of Surgery

BACKGROUND: Appendiceal epithelial neoplasms are rare cancers. Management of peritoneal disease from appendiceal neoplasms has his..

Antagonism of inhibitor of apoptosis proteins enhances CAR T-cell efficacy

J Michie, PA Beavis, AJ Freeman, SJ Vervoort, KM Ramsbottom, V Narasimhan, N Lalaoui, RG Ramsay, RW Johnstone, J Silke, PK Darcy, I Voskoboinik, CJ Kearney, J Oliaro

Conference Proceedings  |  2019  |  BRITISH JOURNAL OF PHARMACOLOGY

Evaluation of cytoreductive surgery and HIPEC for peritoneal surface malignancies: analysis of 384 consecutive cases

Vignesh Narasimhan, Atandrila Das, Satish Warrier, Craig Lynch, Jacob McCormick, Jeanne Tie, Michael Michael, Robert Ramsay, Alexander Heriot

Journal article  |  2019  |  Langenbeck's Archives of Surgery

BCL-2 family protein BOK is a positive regulator of uridine metabolism in mammals

Rahul Srivastava, Zhipeng Cao, Christina Nedeva, Samara Naim, Daniel Bachmann, Tatiana Rabachini, Lahiru Gangoda, Sanjay Shahi, Jason Glab, Joseph Menassa, Laura Osellame, Tao Nelson, Yuniel Fernandez-Marrero, Fiona Brown, Andrew Wei, Francine Ke, Lorraine O'Reilly, Marcel Doerflinger, Cody Allison, Andrew Kueh, et al.

Journal article  |  2019  |  Proceedings of the National Academy of Sciences

BCL-2 family proteins regulate the mitochondrial apoptotic pathway. BOK, a multidomain BCL-2 family protein, is generally believed..

Novel vaccine targeting colonic adenoma: A pre-clinical model

Toan D Pham, Sandra Carpinteri, Shienny Sampurno, Lloyd Pereira, Sara Roth, Vignesh Narasimhan, Kasmira Wilson, Phillip Darcy, Jayesh Desai, Alexander G Heriot, Robert G Ramsay

Conference Proceedings  |  2019  |  Clinical Research (Excluding Clinical Trials)

Colorectal peritoneal metastases: Exploring the immune landscape and the potential of immunotherapy using organoid models

Vignesh Narasimhan, Pham Toan, Kasmira Wilson, Susan Woods, Daniel Worthley, Jeanne Tie, Michael Michael, Alexander Heriot, Robert Ramsay

Conference Proceedings  |  2019  |  Immunology

A novel Pik3ca-driven mouse model and syngeneic cancer cell line for the preclinical testing of targeted and immune therapies for anal squamous cell carcinoma (ASCC)

Glen R Guerra, Sara Roth, Joseph C Kong, Rosemary M Millen, David S Liu, Shienny Sampurno, Vignesh Narasimhan, Toan D Pham, Karen G Montgomery, Alexander G Heriot, Robert G Ramsay, Wayne A Phillips

Conference Proceedings  |  2019  |  Tumor Biology

Patient Derived Organoid to Model Penile Squamous Cell Carcinoma

Jiasian Teh, Glen Guerra, Robert Ramsay, Alexander Heriot, Justin Chee, Nathan Lawrentschuk

Conference Proceedings  |  2019  |  ASIA-PACIFIC JOURNAL OF CLINICAL ONCOLOGY

Phase II trial PD-L1/PD-1 blockade avelumab with chemoradiotherapy for locally advanced resectable T3B-4/N1-2 rectal cancer: The Ave-Rec trial.

Michael Michael, Rachel Wong, Sanjeev Singh Gill, David Goldstein, Sam Ngan, Alexander Graham Heriot, Emma Link, Maria Farrell, Paul J Neeson, Robert George Ramsay, Kasmira Wilson, Catherine Mitchell, Jeanne Tie, Nick Pavlakis, John Raymond Zalcberg, Eva Segelov

Conference Proceedings  |  2019  |  Journal of Clinical Oncology

Outcomes Following Cytoreduction and HIPEC for Pseudomyxoma Peritonei: 10-Year Experience.

Vignesh Narasimhan, Kasmira Wilson, Maneka Britto, Satish Warrier, A Craig Lynch, Michael Michael, Jeanne Tie, Tim Akhurst, Catherine Mitchell, Robert Ramsay, Alexander Heriot

Journal article  |  2019  |  Journal of Gastrointestinal Surgery

BACKGROUND: Pseudomyxoma peritonei (PMP) is a rare clinical presentation, with considerable morbidity and mortality if left untrea..

Prognostic Impact of Tumor-Infiltrating Lymphocytes in Primary and Metastatic Colorectal Cancer: A Systematic Review and Meta-analysis

Joseph C Kong, Glen R Guerra, Pham Toan, Catherine Mitchell, A Craig Lynch, Satish K Warrier, Robert G Ramsay, Alexander G Heriot

Journal article  |  2019  |  Diseases of the Colon & Rectum

Establishment and characterization of a panel of penile squamous cell carcinoma cell lines and organoids representing a spectrum of disease stage and treatment response

J Teh, G Guerra, R Ramsay, J Chee, A Heriot, N Lawrentschuk

Conference Proceedings  |  2019  |  BJU INTERNATIONAL

A Roberts Syndrome Individual With Differential Genotoxin Sensitivity and a DNA Damage Response Defect

Michael J McKay, Jeffery Craig, Paul Kalitsis, Sergei Kozlov, Sandra Verschoor, Phillip Chen, Pavel Lobachevsky, Raja Vasireddy, Yuqian Yan, Jacinta Ryan, George McGillivray, Ravi Savarirayan, Martin F Lavin, Robert G Ramsay, Huiling Xu

Journal article  |  2019  |  International Journal of Radiation Oncology*Biology*Physics

Novel Vaccine Targeting Colonic Adenoma: a Pre-clinical Model

Toan Pham, Sandra Carpinteri, Shienny Sampurno, Lloyd Pereira, Sara Roth, Vignesh Narasimhan, Phillip Darcy, Jayesh Desai, Alexander G Heriot, Robert G Ramsay

Journal article  |  2019  |  Journal of Gastrointestinal Surgery

Evaluating and manipulating the immune landscape in hepatic verses peritoneal metastases arising from colorectal primary tumors

Robert George Ramsay, Rosemary Millen, Vignesh Narasimhan, Sara Roth, Pham Toan, Joseph Kong, Glen Guerra, Wayne A Phillips, Alexander Graham Heriot

Conference Proceedings  |  2019  |  Journal of Clinical Oncology

Antagonism of IAPs Enhances CAR T-cell Efficacy

Jessica Michie, Paul A Beavis, Andrew J Freeman, Stephin J Vervoort, Kelly M Ramsbottom, Vignesh Narasimhan, Emily J Lelliott, Najoua Lalaoui, Robert G Ramsay, Ricky W Johnstone, John Silke, Phillip K Darcy, Ilia Voskoboinik, Conor J Kearney, Jane Oliaro

Journal article  |  2019  |  Cancer Immunology Research

Wither surgical oncology?

Toan D Pham, Vignesh Narasimhan, Glen Guerra, Joseph Kong, Jayesh Desai, Robert Ramsay, Alexander Heriot

Journal article  |  2019  |  ANZ Journal of Surgery

ASO Author Reflections: Immunotherapy for Solid Tumors: A Review

Pham Toan, Sara Roth, Jayesh Desai, Robert Ramsay, Alexander Heriot

Journal article  |  2018  |  Annals of Surgical Oncology

Tumor-Infiltrating Lymphocyte Function Predicts Response to Neoadjuvant Chemoradiotherapy in Locally Advanced Rectal Cancer

Joseph Cherng Huei Kong, Glen Robert Guerra, Rosemary Magdalena Millen, Sara Roth, Huiling Xu, Paul Joseph Neeson, Phillip Kevin Darcy, Michael Henry Kershaw, Shienny Sampurno, Jordane Malaterre, David Shi Hao Liu, Duc Pham Toan, Vignesh Narasimhan, Minyu Wang, Yu-Kuan Huang, Kumar Visvanathan, Jacob McCormick, Andrew Craig Lynch, Satish Warrier, Michael Michael, et al.

Journal article  |  2018  |  JCO Precision Oncology

An Update on Immunotherapy for Solid Tumors: A Review

Toan Pham, Sara Roth, Joseph Kong, Glen Guerra, Vignesh Narasimhan, Lloyd Pereira, Jayesh Desai, Alexander Heriot, Robert Ramsay

Journal article  |  2018  |  Annals of Surgical Oncology

Prognostic value of tumour regression grade in locally advanced rectal cancer: a systematic review and meta-analysis

JC Kong, GR Guerra, SK Warrier, A Craig Lynch, M Michael, SY Ngan, W Phillips, G Ramsay, AG Heriot

Journal article  |  2018  |  Colorectal Disease

Intratumoral MAPK and PI3K signaling pathway heterogeneity in glioblastoma tissue correlates with selective CREB signaling and specific functional gene signatures

Paul Daniel, Gulay Filiz, Martin Tymms, Robert Ramsay, Andrew Henry Kaye, Stanley Stylli, Theo Mantamadiotis

Journal article  |  2018  |  Experimental and Molecular Pathology

Limitations in discovering useful tumor biomarkers and drug targets is not only due to patient-to-patient differences but also due..

Risk Factors Associated With Circumferential Resection Margin Positivity in Rectal Cancer: A Binational Registry Study

Satish K Warrier, Joseph Cherng Kong, Glen R Guerra, Timothy J Chittleborough, Arun Naik, Robert G Ramsay, A Craig Lynch, Alexander G Heriot

Journal article  |  2018  |  Diseases of the Colon & Rectum

Experimental study of delivery of humidified-warm carbon dioxide during open abdominal surgery

S Carpinteri, S Sampurno, J Malaterre, R Millen, M Dean, J Kong, T Chittleborough, A Heriot, AC Lynch, RG Ramsay

Journal article  |  2018  |  British Journal of Surgery

Salvage Surgery for Locoregional Failure in Anal Squamous Cell Carcinoma

Glen R Guerra, Joseph C Kong, Maria-Pia Bernardi, Robert G Ramsay, Wayne A Phillips, Satish K Warrier, A Craig Lynch, Samuel Y Ngan, Alexander G Heriot

Journal article  |  2018  |  Diseases of the Colon & Rectum

Intratumor MAPK and PI3K signaling pathway heterogeneity in glioblastoma tissue correlates with CREB signaling and distinct target gene signatures

PM Daniel, G Filiz, MJ Tymms, RG Ramsay, AH Kaye, SS Stylli, T Mantamadiotis

Journal article  |  2018  |  Experimental and Molecular Pathology

Colonoscopic surveillance: quality, guidelines and effectiveness

Timothy J Chittleborough, Joseph C Kong, Glen R Guerra, Robert Ramsay, Alexander G Heriot

Journal article  |  2018  |  ANZ Journal of Surgery

Clinical research and the medical research future fund

Michael Berk, Rob Ramsay

Journal article  |  2017  |  Australian & New Zealand Journal of Psychiatry

Improving trial design in cancer anesthesia (onco-anesthesia) research

Jonathan G Hiller, Paul S Myles, Rob G Ramsay, Bernhard J Riedel

Journal article  |  2017  |  Canadian Journal of Anesthesia/Journal canadien d'anesthésie

Impact of celecoxib on inflammation during cancer surgery: a randomized clinical trial

Jonathan G Hiller, Shienny Sampurno, Rosemary Millen, Niketh Kuruvilla, Kwok M Ho, Rob Ramsay, Bernhard Riedel

Journal article  |  2017  |  Canadian Journal of Anesthesia/Journal canadien d'anesthésie

Warmed, humidified CO2 insufflation benefits intraoperative core temperature during laparoscopic surgery: A meta-analysis

Meara Dean, Robert Ramsay, Alexander Heriot, John Mackay, Richard Hiscock, A Craig Lynch

Journal article  |  2017  |  Asian Journal of Endoscopic Surgery

Outcome and Salvage Surgery Following "Watch and Wait" for Rectal Cancer after Neoadjuvant Therapy: A Systematic Review

Joseph C Kong, Glen R Guerra, Satish K Warrier, Robert G Ramsay, Alexander G Heriot

Journal article  |  2017  |  Diseases of the Colon & Rectum

SCA-1 Labels a Subset of Estrogen-Responsive Bipotential Repopulating Cells within the CD24( ) CD49f(hi) Mammary Stem Cell-Enriched Compartment

Genevieve V Dall, Jessica L Vieusseux, Kenneth S Korach, Yukitomo Arao, Sylvia C Hewitt, Katherine J Hamilton, Elaine Dzierzak, Wah Chin Boon, Evan R Simpson, Robert G Ramsay, Torsten Stein, Joanne S Morris, Robin L Anderson, Gail P Risbridger, Kara L Britt

Journal article  |  2017  |  Stem Cell Reports

Exploiting induced senescence in intestinal organoids to drive enteroendocrine cell expansion.

Robert G Ramsay, Helen E Abud

Journal article  |  2017  |  Stem Cell Investigation

Intestinal-specific activatable Myb initiates colon tumorigenesis in mice

J Malaterre, L Pereira, T Putoczki, R Millen, S Paquet-Fifield, M Germann, J Liu, D Cheasley, S Sampurno, SA Stacker, MG Achen, RL Ward, P Waring, T Mantamadiotis, M Ernst, RG Ramsay

Journal article  |  2016  |  Oncogene

Predicting pathological complete response to neoadjuvant chemoradiotherapy in locally advanced rectal cancer: a systematic review

JE Ryan, SK Warrier, AC Lynch, RG Ramsay, WA Phillips, AG Heriot

Journal article  |  2016  |  Colorectal Disease

CDK9 inhibitors selectively target estrogen receptor-positive breast cancer cells through combined inhibition of MYB and MCL-1 expression

Partha Mitra, Ren-Ming Yang, James Sutton, Robert G Ramsay, Thomas J Gonda

Journal article  |  2016  |  Oncotarget

Adenoid Cystic Carcinoma Can Be Driven by MYB or MYBL1 Rearrangements: New Insights into MYB and Tumor Biology

Thomas J Gonda, Robert G Ramsay

Journal article  |  2016  |  Cancer Discovery

Immunomodulation by MYB is associated with tumor relapse in patients with early stage colorectal cancer

Rosemary Millen, Jordane Malaterre, Ryan S Cross, Sandra Carpinteri, Jayesh Desai, Ben Tran, Phillip Darcy, Peter Gibbs, Oliver Sieber, Nikolajs Zeps, Paul Waring, Stephen Fox, Lloyd Pereira, Robert G Ramsay

Journal article  |  2016  |  OncoImmunology

New Insights on COX-2 in Chronic Inflammation Driving Breast Cancer Growth and Metastasis

Honor J Hugo, C Saunders, RG Ramsay, EW Thompson

Journal article  |  2015  |  Journal of Mammary Gland Biology and Neoplasia

Molecular biology of anal squamous cell carcinoma: implications for future research and clinical intervention

Maria-Pia Bernardi, Samuel Y Ngan, Michael Michael, A Craig Lynch, Alexander G Heriot, Robert G Ramsay, Wayne A Phillips

Journal article  |  2015  |  The Lancet Oncology

Peritoneal Tumorigenesis and Inflammation are Ameliorated by Humidified-Warm Carbon Dioxide Insufflation in the Mouse

Sandra Carpinteri, Shienny Sampurno, Maria-Pia Bernardi, Markus Germann, Jordane Malaterre, Alexander Heriot, Brenton A Chambers, Steven E Mutsaers, Andrew C Lynch, Robert G Ramsay

Journal article  |  2015  |  Annals of Surgical Oncology

Directly targeting transcriptional dysregulation in cancer

Thomas J Gonda, Robert G Ramsay

Journal article  |  2015  |  Nature Reviews Cancer

BET inhibitor resistance emerges from leukaemia stem cells

Chun Yew Fong, Omer Gilan, Enid YN Lam, Alan F Rubin, Sarah Ftouni, Dean Tyler, Kym Stanley, Devbarna Sinha, Paul Yeh, Jessica Morison, George Giotopoulos, Dave Lugo, Philip Jeffrey, Stanley Chun-Wei Lee, Christopher Carpenter, Richard Gregory, Robert G Ramsay, Steven W Lane, Omar Abdel-Wahab, Tony Kouzarides, et al.

Journal article  |  2015  |  Nature

Defective Myb Function Ablates Cyclin E1 Expression and Perturbs Intestinal Carcinogenesis

Dane Cheasley, Lloyd Pereira, Shienny Sampurno, Oliver Sieber, Robert Jorissen, Huiling Xu, Markus Germann, Yuqian Yan, Robert G Ramsay, Jordane Malaterre

Journal article  |  2015  |  Molecular Cancer Research

Frizzled7 Functions as a Wnt Receptor in Intestinal Epithelial Lgr5( ) Stem Cells

Dustin J Flanagan, Toby J Phesse, Nick Barker, Renate HM Schwab, Nancy Amin, Jordane Malaterre, Daniel E Stange, Cameron J Nowell, Scott A Currie, Jarel TS Saw, Eva Beuchert, Robert G Ramsay, Owen J Sansom, Matthias Ernst, Hans Clevers, Elizabeth Vincan

Journal article  |  2015  |  Stem Cell Reports

MYB Elongation Is Regulated by the Nucleic Acid Binding of NF kappa B p50 to the Intronic Stem-Loop Region

Lloyd A Pereira, Honor J Hugo, Jordane Malaterre, Huiling Xu, Secondo Sonza, Alina Cures, Damian FJ Purcell, Paul A Ramsland, Steven Gerondakis, Thomas J Gonda, Robert G Ramsay

Journal article  |  2015  |  PLOS ONE

Myb via TGF beta is required for collagen type 1 production and skin integrity

Shienny Sampurno, Ryan Cross, Helen Pearson, Pritinder Kaur, Jordane Malaterre, Robert G Ramsay

Journal article  |  2015  |  Growth Factors

Therapeutic DNA vaccination against colorectal cancer by targeting the MYB oncoprotein

Ryan S Cross, Jordane Malaterre, Alexander J Davenport, Sandra Carpinteri, Robin L Anderson, Phillip K Darcy, Robert G Ramsay

Journal article  |  2015  |  Clinical & Translational Immunology

Cohesin Rad21 Mediates Loss of Heterozygosity and Is Upregulated via Wnt Promoting Transcriptional Dysregulation in Gastrointestinal Tumors

Huiling Xu, Yuqian Yan, Siddhartha Deb, Danny Rangasamy, Markus Germann, Jordane Malaterre, Noreen C Eder, Robyn L Ward, Nicholas J Hawkins, Richard W Tothill, Long Chen, Neil J Mortensen, Stephen B Fox, Michael J McKay, Robert G Ramsay

Journal article  |  2014  |  Cell Reports

Tripartite interactions between Wnt signaling, Notch and Myb for stem/progenitor cell functions during intestinal tumorigenesis

Markus Germann, Huiling Xu, Jordane Malaterre, Shienny Sampurno, Mathilde Huyghe, Dane Cheasley, Silvia Fre, Robert G Ramsay

Journal article  |  2014  |  Stem Cell Research

Marker genes identify three somatic cell types in the fetal mouse ovary

Raphael H Rastetter, Pascal Bernard, James S Palmer, Anne-Amandine Chassot, Huijun Chen, Patrick S Western, Robert G Ramsay, Marie-Christine Chaboissier, Dagmar Wilhelm

Journal article  |  2014  |  Developmental Biology

Partial inhibition of gp130-Jak-Stat3 signaling prevents Wnt-beta-catenin-mediated intestinal tumor growth and regeneration

Toby J Phesse, Michael Buchert, Emma Stuart, Dustin J Flanagan, Maree Faux, Shoukat Afshar-Sterle, Francesca Walker, Hui-Hua Zhang, Cameron J Nowell, Robert Jorissen, Chin Wee Tan, Yumiko Hirokawa, Moritz F Eissmann, Ashleigh R Poh, Jordane Malaterre, Helen B Pearson, David G Kirsch, Paolo Provero, Valeria Poli, Robert G Ramsay, et al.

Journal article  |  2014  |  Science Signaling

Selective CREB-dependent cyclin expression mediated by the PI3K and MAPK pathways supports glioma cell proliferation

P Daniel, G Filiz, DV Brown, F Hollande, M Gonzales, G D'Abaco, N Papalexis, WA Phillips, J Malaterre, RG Ramsay, T Mantamadiotis

Journal article  |  2014  |  Nature

RAD21 cohesin overexpression is a prognostic and predictive marker exacerbating poor prognosis in KRAS mutant colorectal carcinomas

S Deb, H Xu, J Tuynman, J George, Y Yan, J Li, RL Ward, N Mortensen, NJ Hawkins, MJ McKay, RG Ramsay, SB Fox

Journal article  |  2014  |  British Journal of Cancer

Physiological expression of the PI3K-activating mutation Pik3ca(H1047R) combines with Apc loss to promote development of invasive intestinal adenocarcinomas in mice

Lauren M Hare, Toby J Phesse, Paul M Waring, Karen G Montgomery, Kathryn M Kinross, Kevin Mills, Vincent Roh, Joan K Heath, Robert G Ramsay, Matthias Ernst, Wayne A Phillips

Journal article  |  2014  |  Biochemical Journal

Inhibition of Established Micrometastases by Targeted Drug Delivery via Cell Surface-Associated GRP78

Yu Rebecca Miao, Bedrich L Eckhardt, Yuan Cao, Renata Pasqualini, Pedram Argani, Wadih Arap, Robert G Ramsay, Robin L Anderson

Journal article  |  2013  |  Clinical Cancer Research

The Myb-p300-CREB axis modulates intestine homeostasis, radiosensitivity and tumorigenesis

S Sampurno, A Bijenhof, D Cheasley, H Xu, S Robine, D Hilton, WS Alexander, L Pereira, T Mantamadiotis, J Malaterre, RG Ramsay

Journal article  |  2013  |  Cell Death & Disease

The CSF-1 receptor fashions the intestinal stem cell niche

Dilara Akcora, Duy Huynh, Sally Lightowler, Markus Germann, Sylvie Robine, Jan R de May, Jeffrey W Pollard, E Richard Stanley, Jordane Malaterre, Robert G Ramsay

Journal article  |  2013  |  Stem Cell Research

CSF-1 Receptor-Dependent Colon Development, Homeostasis and Inflammatory Stress Response

Huynh Duy, Dilara Akcora, Jordane Malaterre, Chee Kai Chan, Xu-Ming Dai, Ivan Bertoncello, E Richard Stanley, Robert G Ramsay

Journal article  |  2013  |  PLoS One

Delayed development of specific thyroid hormone-regulated events in transthyretin null mice

Julie A Monk, Natalie A Sims, Katarzyna M Dziegielewska, Roy E Weiss, Robert G Ramsay, Samantha J Richardson

Journal article  |  2013  |  American Journal of Physiology - Endocrinology and Metabolism

Myb and the Regulation of Stem Cells in the Intestine and Brain: A Tale of Two Niches

Jordane Malaterre, Lloyd Pereira, Robert G Ramsay

Journal article  |  2013  |  Advances in Experimental Medicine and Biology

Direct repression of MYB by ZEB1 suppresses proliferation and epithelial gene expression during epithelial-to-mesenchymal transition of breast cancer cells

Honor J Hugo, Lloyd Pereira, Randy Suryadinata, Yvette Drabsch, Thomas J Gonda, NPA Devika Gunasinghe, Cletus Pinto, Eliza TL Soo, Bryce JW van denderen, Prue Hill, Robert G Ramsay, Boris Sarcevic, Donald F Newgreen, Erik W Thompson

Journal article  |  2013  |  Breast Cancer Research

Cohesin regulates tissue-specific expression by stabilizing highly occupied cis-regulatory modules

Andre J Faure, Dominic Schmidt, Stephen Watt, Petra C Schwalie, Michael D Wilson, Huiling Xu, Robert G Ramsay, Duncan T Odom, Paul Flicek

Journal article  |  2012  |  Genome Research

The tumor suppressor Apc controls planar cell polarities central to gut homeostasis

Julien Bellis, Isabelle Duluc, Beatrice Romagnolo, Christine Perret, Maree C Faux, Denis Dujardin, Caroline Formstone, Sally Lightowler, Robert G Ramsay, Jean-Noel Freund, Jan R De Mey

Journal article  |  2012  |  Journal of Cell Biology

Estrogen receptor-alpha recruits P-TEFb to overcome transcriptional pausing in intron 1 of the MYB gene

Partha Mitra, Lloyd A Pereira, Yvette Drabsch, Robert G Ramsay, Thomas J Gonda

Journal article  |  2012  |  Nucleic Acids Research

RAD21 Mutations Cause a Human Cohesinopathy

Matthew A Deardorff, Jonathan J Wilde, Melanie Albrecht, Emma Dickinson, Stephanie Tennstedt, Diana Braunholz, Maren Moennich, Yuqian Yan, Weizhen Xu, Maria Concepcion Gil-Rodriguez, Dinah Clark, Hakon Hakonarson, Sara Halbach, Laura Daniela Michelis, Abhinav Rampuria, Eva Rossier, Stephanie Spranger, Lionel Van Maldergem, Sally Ann Lynch, Gabriele Gillessen-Kaesbach, et al.

Journal article  |  2012  |  American Journal of Human Genetics

Enhanced Lithium-Induced Brain Recovery Following Cranial Irradiation Is Not Impeded by Inflammation

Jordane Malaterre, Cameron S McPherson, Delphine Denoyer, Emily Lai, Jim Hagekyriakou, Sally Lightowler, Koishi Shudo, Matthias Ernst, David M Ashley, Jennifer L Short, Greg Wheeler, Robert G Ramsay

Journal article  |  2012  |  Stem Cells Translational Medicine

Myb: Getting involved in EMT

Robert Ramsay

Journal article  |  2012  |  Cell Cycle

Colorectal cancer mouse models: Integrating inflammation and the stroma

Matthias Ernst, Robert G Ramsay

Journal article  |  2012  |  Journal of Gastroenterology and Hepatology

Myb Controls Intestinal Stem Cell Genes and Self-Renewal

Dane Cheasley, Lloyd Pereira, Sally Lightowler, Elizabeth Vincan, Jordane Malaterre, Robert G Ramsay

Journal article  |  2011  |  Stem Cells

Wnt signaling and colon tumorigenesis - A view from the periphery

Antony W Burgess, Maree C Faux, Meredith J Layton, Robert G Ramsay

Journal article  |  2011  |  Experimental Cell Research

MYB Is Essential for Mammary Tumorigenesis

Rebecca Yu Miao, Yvette Drabsch, Ryan Stanley Cross, Dane Cheasley, Sandra Carpinteri, Lloyd Pereira, Jordane Malaterre, Thomas J Gonda, Robin L Anderson, Robert G Ramsay

Journal article  |  2011  |  Cancer Research

Colony-Stimulating Factor-1 Promotes Kidney Growth and Repair via Alteration of Macrophage Responses

Maliha A Alikhan, Christina V Jones, Timothy M Williams, Anthony G Beckhouse, Anne L Fletcher, Michelle M Kett, Samy Sakkal, Chrishan S Samuel, Robert G Ramsay, James A Deane, Christine A Wells, Melissa H Little, David A Hume, Sharon D Ricardo

Journal article  |  2011  |  American Journal of Pathology

PHLDA1 Expression Marks the Putative Epithelial Stem Cells and Contributes to Intestinal Tumorigenesis

Anuratha Sakthianandeswaren, Michael Christie, Carla D'Andreti, Cary Tsui, Robert N Jorissen, Shan Li, Nicholas I Fleming, Peter Gibbs, Lara Lipton, Jordane Malaterre, Robert G Ramsay, Toby J Phesse, Matthias Ernst, Rosemary E Jeffery, Richard Poulsom, Simon J Leedham, Stefania Segditsas, Ian PM Tomlinson, Oliver K Bernhard, Richard J Simpson, et al.

Journal article  |  2011  |  Cancer Research

Professor Alan M Gewirtz (1949-2010) OBITUARY

TP Bender, TJ Gonda, J Frampton, SA Ness, RG Ramsay

Journal article  |  2011  |  Oncogene

Enhanced RAD21 cohesin expression confers poor prognosis and resistance to chemotherapy in high grade luminal, basal and HER2 breast cancers

Huiling Xu, Max Yan, Jennifer Patra, Rachael Natrajan, Yuqian Yan, Sigrid Swagemakers, Jonathan M Tomaszewski, Sandra Verschoor, Ewan KA Millar, Peter van der Spek, Jorge S Reis-Filho, Robert G Ramsay, Sandra A O'Toole, Catriona M McNeil, Robert L Sutherland, Michael J Mckay, Stephen B Fox

Journal article  |  2011  |  Breast Cancer Research

Rad21-Cohesin Haploinsufficiency Impedes DNA Repair and Enhances Gastrointestinal Radiosensitivity in Mice

Huiling Xu, Kuhendra Balakrishnan, Jordane Malaterre, Matthew Beasley, Yuqian Yan, Jeroen Essers, Esther Appeldoorn, Jonathan M Thomaszewski, Melisa Vazquez, Sandra Verschoor, Martin F Lavin, Ivan Bertonchello, Robert G Ramsay, Michael J Mckay

Journal article  |  2010  |  PLoS One

MYB suppresses differentiation and apoptosis of human breast cancer cells

Yvette Drabsch, Robert G Ramsay, Thomas J Gonda

Journal article  |  2010  |  Breast Cancer Research

Intestinal adenoma formation and MYC activation are regulated by cooperation between MYB and Wnt signaling

D Ciznadija, R Tothill, ML Waterman, L Zhao, D Huynh, RM Yu, M Ernst, S Ishii, T Mantamadiotis, TJ Gonda, RG Ramsay, J Malaterre

Journal article  |  2009  |  Cell Death & Differentiation

Snail2 transcriptionally represses MYB in EMT induced by hypoxia in breast cancer cell lines

Honor J Hugo, Donald F Newgreen, Yvette Drabsch, Robert G Ramsay, Gonda J Tom, Erik W Thompson

Journal article  |  2009  |  CLINICAL & EXPERIMENTAL METASTASIS

Inhibition of mammary tumor growth and metastasis by targeting cell surface associated GRP78

Rebecca Y Miao, Connie Sun, Renata Pasqualini, Wadih Arap, Robert G Ramsay, Robin L Anderson

Journal article  |  2009  |  CLINICAL & EXPERIMENTAL METASTASIS

Colony Stimulating Factor-1 Dependence of Paneth Cell Development in the Mouse Small Intestine

Duy Huynh, Xu-Ming Dai, Sayan Nandi, Sally Lightowler, Melanie Trivett, Chee-Kai Chan, Ivan Bertoncello, Robert G Ramsay, E Richard Stanley

Journal article  |  2009  |  Gastroenterology

The role of c-Myb in tumorigenesis and mammary gland development

Yu Miao, Sally Lightowler, Tom Gonda, Robin Anderson, Robert Ramsay

Journal article  |  2009  |  CANCER RESEARCH

cAMP Response Element Binding Protein Is Required for Mouse Neural Progenitor Cell Survival and Expansion

Sebastian Dworkin, Jordane Malaterre, Frederic Hollande, Phillip K Darcy, Robert G Ramsay, Theo Mantamadiotis

Journal article  |  2009  |  Stem Cells

Induction of T cell-mediated immunity using a c-Myb DNA vaccine in a mouse model of colon cancer

Benjamin B Williams, Meg Wall, Rebecca Yu Miao, Brenda Williams, Ivan Bertoncello, Michael H Kershaw, Theo Mantamadiotis, Michelle Haber, Murray D Norris, Anand Gautam, Phillip K Darcy, Robert G Ramsay

Journal article  |  2008  |  Cancer Immunology, Immunotherapy

MYB function in normal and cancer cells

Robert G Ramsay, Thomas J Gonda

Journal article  |  2008  |  Nature Reviews Cancer

Estrogen and MYB in breast cancer: potential for new therapies

Thomas J Gonda, Paul Leo, Robert G Ramsay

Journal article  |  2008  |  Expert Opinion on Biological Therapy

Mechanism of and requirement for estrogen-regulated MYB expression in estrogen-receptor-positive breast cancer cells (vol 104, pg 13762, 2007)

Yvette Drabsch, Honor Hugo, Rui Zhang, Dennis H Dowhan, Yu Rebecca Miao, Alan M Gewirtz, Simon C Barry, Robert G Ramsay, Thomas J Gonda

Journal article  |  2008  |  Proceedings of the National Academy of Sciences

c-Myb is required for neural progenitor cell proliferation and maintenance of the neural stem cell niche in adult brain

Jordane Malaterre, Theo Mantamadiotis, Sebastian Dworkin, Sally Lightowler, Qing Yang, Mark I Ransome, Ann M Turnley, Nancy R Nichols, Nikla R Emambokus, Jon Frampton, Robert G Ramsay

Journal article  |  2008  |  Stem Cells

A novel magnetic bead-based assay with high sensitivity and selectivity for analysis of telomerase in exfoliated cells from patients with bladder and colon cancer

Julie Rothacker, Robert G Ramsay, Daniel Ciznadija, Emma Gras, Craig B Neylon, Ngaire J Elwood, David Bouchier-Hayes, Peter Gibbs, Mark A Rosenthal, Edouard C Nice

Journal article  |  2007  |  Electrophoresis

Insights into c-Myb functions through investigating colonic crypts

Robert G Ramsay, Jordane Malaterre

Journal article  |  2007  |  Blood Cells Molecules and Diseases

Mechanism of and requirement for estrogen-regulated MYB expression in estrogen-receptor-positive breast cancer cells

Yvette Drabsch, Honor Hugo, Rui Zhang, Dennis H Dowhan, Yu Rebecca Miao, Alan M Gewirtz, Simon C Barry, Robert G Ramsay, Thomas J Gonda

Journal article  |  2007  |  Proceedings of the National Academy of Sciences of the United States of America

CREB activity modulates neural cell proliferation, midbrain-hindbrain organization and patterning in zebrafish

Sebastian Dworkin, Joan K Heath, Tanya A deJong-Curtain, Benjamin M Hogan, Graham J Lieschke, Jordane Malaterre, Robert G Ramsay, Theo Mantamadiotis

Journal article  |  2007  |  Developmental Biology

Oncogenic properties of HIV-Tat in colorectal cancer cells

Duy Huynh, Elizabeth Vincan, Theo Mantamadiotis, Damian Purcell, Chee-Kai Chan, Robert Ramsay

Journal article  |  2007  |  Current HIV Research

Licensing regulators geminin and CDT1 identify progenitor cells of the mouse CNS in a specific phase of the cell cycle

M Spella, O Britz, P Kotantaki, Z Lygerou, H Nishitani, RG Ramsay, C Flordellis, F Guillemot, T Mantamadiotis, S Taraviras

Journal article  |  2007  |  Neuroscience

Frizzled-7 dictates three-dimensional organization of colorectal cancer cell carcinoids

E Vincan, PK Darcy, CA Farrelly, MC Faux, T Brabletz, RG Ramsay

Journal article  |  2007  |  Oncogene

c-Myb is required for progenitor cell homeostasis in colonic crypts

Jordane Malaterre, Marina Carpinelli, Matthias Ernst, Warren Alexander, Michael Cooke, Susan Sutton, Sebastian Dworkin, Joan K Heath, Jon Frampton, Grant McArthur, Hans Clevers, Douglas Hilton, Theo Mantamadiotis, Robert G Ramsay

Journal article  |  2007  |  Proceedings of the National Academy of Sciences of the United States of America

Collagen loss and impaired wound healing is associated with c-Myb deficiency

Z Kopecki, MM Luchetti, DH Adams, X Strudwick, T Mantamadiotis, A Stoppacciaro, A Gabrielli, RG Ramsay, AJ Cowin

Journal article  |  2007  |  Journal of Pathology

A human three-dimensional cell line model allows the study of dynamic and reversible epithelial-mesenchymal and mesenchymal-epithelial transition that underpins colorectal carcinogenesis

Elizabeth Vincan, Thomas Brabletz, Maree C Faux, Robert G Ramsay

Journal article  |  2007  |  Cells Tissues Organs

WNT-Frizzled signalling and the many paths to neural development and adult brain homeostasis

Jordane Malaterre, Robert G Ramsay, Theo Mantamadiotis

Journal article  |  2007  |  Frontiers in Bioscience

Proto-oncogene c-Myb regulates neural progenitor proliferation in adult brain

J Malaterre, T Mantamadiotis, AM Turnley, J Frampton, RG Ramsay

Conference Proceedings  |  2006  |  International Journal of Developmental Neuroscience

Mutations in the MYB intron I regulatory sequence increase transcription in colon cancers

Honor Hugo, Alina Cures, Nirosha Suraweera, Yvette Drabsch, Damian Purcell, Theo Mantamadiotis, Wayne Phillips, Alex Dobrovic, Gabriella Zupi, Thomas J Gonda, Barry Iacopetta, Robert G Ramsay

Journal article  |  2006  |  Genes, Chromosomes & Cancer

Hypothalamic 3 ',5 '-cyclic adenosine monophosphate response element-binding protein loss causes anterior pituitary hypoplasia and dwarfism in mice

T Mantamadiotis, O Kretz, S Ridder, SC Bleckmann, D Bock, HJ Grone, J Malaterre, S Dworkin, RG Ramsay, G Schutz

Journal article  |  2006  |  Molecular Endocrinology

c-Myb a stem-progenitor cell regulator in multiple tissue compartments

RG Ramsay

Journal article  |  2005  |  Growth Factors

A multicenter phase II trial of thalidomide and celecoxib for patients with relapsed and refractory multiple myeloma

HM Prince, L Mileshkin, A Roberts, V Ganju, C Underhill, J Catalano, R Bell, JF Seymour, D Westerman, PJ Simmons, K Lillie, AD Milner, J Di Iulio, JB Zeldis, R Ramsay

Journal article  |  2005  |  Clinical Cancer Research

Expression of stress response protein glucose regulated protein-78 mediated by c-Myb

RG Ramsay, D Ciznadija, T Mantamadiotis, R Anderson, R Pearson

Journal article  |  2005  |  International Journal of Biochemistry and Cell Biology

Frizzled-7 receptor ectodomain expression in a colon cancer cell line induces morphological change and attenuates tumor growth

E Vincan, PK Darcy, MJ Smyth, EW Thompson, RJS Thomas, WA Phillips, RG Ramsay

Journal article  |  2005  |  Differentiation

Colon epithelial cell differentiation is inhibited by constitutive c-myb expression or mutant APC plus activated RAS

RG Ramsay, D Ciznadija, C Sicurella, N Reyes, K Mitchelhill, PK Darcy, G D'Abaco, T Mantamadiotis

Journal article  |  2005  |  DNA and Cell Biology

CREB function is required for normal thymic cellularity and post-irradiation recovery

S Baumann, B Kyewski, SC Bleckmann, E Greiner, D Rudolph, W Schmid, RG Ramsay, PH Krammer, G Schutz, T Mantamadiotis

Journal article  |  2004  |  European Journal of Immunology

Colony-stimulating factor-1 promotes clonogenic growth of normal murine colonic crypt epithelial cells in vitro

RG Ramsay, SJ Micallef, B Williams, S Lightowler, E Vincan, JK Heath, T Mantamadiotis, I Bertoncello

Journal article  |  2004  |  Journal of Interferon and Cytokine Research

c-myb heterozygous mice are hypersensitive to 5-fluorouracil and ionizing radiation

RG Ramsay, S Micallef, S Lightowler, ML Mucenski, T Mantamadiotis, I Bertoncello

Journal article  |  2004  |  Molecular Cancer Research

Suppressor screen in Mpl(-/-) mice: c-Myb mutation causes supraphysiological production of platelets in the absence of thrombopoietin signaling

MR Carpinelli, DJ Hilton, D Metcalf, JL Antonchuk, CD Hyland, SL Mifsud, L Di Rago, AA Hilton, TA Willson, AW Roberts, RG Ramsay, NA Nicola, WS Alexander

Journal article  |  2004  |  Proceedings of the National Academy of Sciences of the United States of America

Transcriptional regulation of cyclo-oxygenase expression: Three pillars of control

RG Ramsay, D Ciznadija, M Vanevski, T Mantamadiotis

Journal article  |  2003  |  International Journal of Immunopathology and Pharmacology

Targeting c-Myb expression in human disease

RG Ramsay, AL Barton, TJ Gonda

Journal article  |  2003  |  Expert Opinion On Therapeutic Targets

Overexpression of wild-type p53 in lichen sclerosus adjacent to human papillomavirus-negative vulvar cancer

K Vanin, J Scurry, H Thorne, K Yuen, RG Ramsay

Journal article  |  2002  |  Journal of Investigative Dermatology

Characterization of interactions between transcription factors and a regulatory region spanning nt-320 to-281 of the HIV-1 LTR in T-lymphoid and non-T-lymphoid cells

LA Pereira, MJ Churchill, AG Elefanty, T Gouskos, PF Lambert, RG Ramsay, NJ Deacon

Journal article  |  2002  |  Journal of Biomedical Science

c-Myb influences HIV type 1 gene expression and virus production

MJ Churchill, RG Ramsay, DI Rhodes, NJ Deacon

Journal article  |  2001  |  AIDS Research and Human Retroviruses

c-Myb and Bcl-x overexpression predicts poor prognosis in colorectal cancer - Clinical and experimental findings

A Biroccio, B Benassi, I D'Agnano, C D'Angelo, S Buglioni, M Mottolese, A Ricciotti, G Citro, M Cosimelli, RG Ramsay, B Calabretta, G Zupi

Journal article  |  2001  |  American Journal of Pathology

Constitutive c-Myb amino-terminal phosphorylation and DNA binding activity uncoupled during entry and passage through the cell cycle

A Cures, C House, C Kanei-Ishii, B Kemp, RG Ramsay

Journal article  |  2001  |  Oncogene

Defective stem cell factor expression in c-myb null fetal liver stroma

C Sicurella, R Freeman, S Micallef, ML Mucenski, I Bertoncello, RG Ramsay

Journal article  |  2001  |  Blood Cells Molecules and Diseases

The Second International Workshop on Myb Genes: Foreword

T Gonda, R Ramsay

Conference Proceedings  |  2001  |  Blood Cells, Molecules, and Diseases

Cyclooxygenase-2, a colorectal cancer nonsteroidal anti-inflammatory drug target, is regulated by c-MYB

RG Ramsay, A Friend, Y Vizantios, R Freeman, C Sicurella, F Hammett, J Armes, D Venter

Journal article  |  2000  |  Cancer Research

c-Myb is critical for murine colon development

M Zorbas, C Sicurella, I Bertoncello, D Venter, S Ellis, ML Mucenski, RG Ramsay

Journal article  |  1999  |  Oncogene

Phosphorylation at the cyclin-dependent kinases site (Thr(85)) of parathyroid hormone-related protein negatively regulates its nuclear localization

MHC Lam, CM House, T Tiganis, KI Mitchelhill, B Sarcevic, A Cures, R Ramsay, BE Kemp, TJ Martin, MT Gillespie

Journal article  |  1999  |  Journal of Biological Chemistry

c-Myb down-regulation is associated with human colon cell differentiation, apoptosis, and decreased Bcl-2 expression

MA Thompson, MA Rosenthal, SL Ellis, AJ Friend, MI Zorbas, RH Whitehead, RG Ramsay

Journal article  |  1998  |  Cancer Research

Minimal truncation of the c-myb gene product in rapid-onset B-cell lymphoma

WP Jiang, MR Kanter, I Dunkel, RG Ramsay, KL Beemon, WS Hayward

Journal article  |  1997  |  Journal of virology

Microsatellite deletions in the c-myb transcriptional attenuator region associated with over-expression in colon tumour cell lines

MA Thompson, R Flegg, EH Westin, RG Ramsay

Journal article  |  1997  |  Oncogene

Colonic expression of c-myb is initiated in utero and continues throughout adult life

MA Rosenthal, MA Thompson, S Ellis, RH Whitehead, RG Ramsay

Journal article  |  1996  |  Cell Growth and Differentiation

REGULATION OF C-MYB THROUGH PROTEIN-PHOSPHORYLATION AND LEUCINE-ZIPPER INTERACTIONS

RG RAMSAY, N MORRICE, P VANEEDEN, V KANAGASUNDARAM, T NOMURA, J DEBLAQUIERE, S ISHII, R WETTENHALL

Journal article  |  1995  |  Oncogene

MYB - AN OLD ONCOPROTEIN WITH NEW ROLES

MA THOMPSON, RG RAMSAY

Journal article  |  1995  |  BioEssays

DNA-binding studies using in vitro synthesized Myb proteins.

RG Ramsay

Journal article  |  1995  |  Methods in molecular biology (Clifton, N.J.)

NEGATIVE AUTOREGULATION OF C-MYB ACTIVITY BY HOMODIMER FORMATION THROUGH THE LEUCINE-ZIPPER

T NOMURA, N SAKAI, A SARAI, T SUDO, C KANEIISHII, RG RAMSAY, D FAVIER, TJ GONDA, S ISHII

Journal article  |  1993  |  Journal of Biological Chemistry

MYB EXPRESSION IS HIGHER IN MALIGNANT HUMAN COLONIC-CARCINOMA AND PREMALIGNANT ADENOMATOUS POLYPS THAN IN NORMAL MUCOSA

RG RAMSAY, MA THOMPSON, JA HAYMAN, G REID, TJ GONDA, RH WHITEHEAD

Journal article  |  1992  |  Cell growth & differentiation : the molecular biology journal of the American Association for Cancer Research

A NOVEL GENE CONSTITUTIVELY EXPRESSED IN HUMAN LYMPHOID-CELLS IS INDUCIBLE WITH INTERFERON-GAMMA IN MYELOID CELLS

JA TRAPANI, KA BROWNE, MJ DAWSON, RG RAMSAY, RL EDDY, TB SHOWS, PC WHITE, B DUPONT

Journal article  |  1992  |  Immunogenetics

TRANSACTIVATION AND TRANSFORMATION BY MYB ARE NEGATIVELY REGULATED BY A LEUCINE-ZIPPER STRUCTURE

C KANEIISHII, EM MACMILLAN, T NOMURA, A SARAI, RG RAMSAY, S AIMOTO, S ISHII, TJ GONDA

Journal article  |  1992  |  Proceedings of the National Academy of Sciences

INTERACTION OF THE MYB PROTEIN WITH SPECIFIC DNA-BINDING SITES

RG RAMSAY, S ISHII, TJ GONDA

Journal article  |  1992  |  Journal of Biological Chemistry

INCREASE IN SPECIFIC DNA-BINDING BY CARBOXYL TRUNCATION SUGGESTS A MECHANISM FOR ACTIVATION OF MYB

RG RAMSAY, S ISHII, TJ GONDA

Journal article  |  1991  |  Oncogene

Two isoforms of murine hck, generated by utilization of alternative translational initiation codons, exhibit different patterns of subcellular localization.

P Lock, S Ralph, E Stanley, I Boulet, R Ramsay, AR Dunn

Journal article  |  1991  |  Molecular and Cellular Biology

Mammalian hck, a member of the src family of tyrosine kinases, is expressed predominantly in cells of the myeloid and B-lymphoid l..

TRANSFORMATION BY CARBOXYL-DELETED MYB REFLECTS INCREASED TRANSACTIVATING CAPACITY AND DISRUPTION OF A NEGATIVE REGULATORY DOMAIN

YL HU, RG RAMSAY, C KANEIISHII, S ISHII, TJ GONDA

Journal article  |  1991  |  Oncogene

MURINE MYELOID CELL-LINES DERIVED BY INVITRO INFECTION WITH RECOMBINANT C-MYB RETROVIRUSES EXPRESS MYB FROM REARRANGED VECTOR PROVIRUSES

TJ GONDA, RG RAMSAY, GR JOHNSON

Journal article  |  1989  |  The EMBO Journal

ACTIVATION OF C-MYB BY CARBOXY-TERMINAL TRUNCATION - RELATIONSHIP TO TRANSFORMATION OF MURINE HEMATOPOIETIC-CELLS INVITRO

TJ GONDA, C BUCKMASTER, RG RAMSAY

Journal article  |  1989  |  The EMBO Journal

MODULATION OF THE C-MYB, C-MYC AND P53 MESSENGER-RNA AND PROTEIN-LEVELS DURING INDUCED MURINE ERYTHROLEUKEMIA CELL-DIFFERENTIATION

VM RICHON, RG RAMSAY, RA RIFKIND, PA MARKS

Journal article  |  1989  |  Oncogene

CHARACTERIZATION OF ALTERNATE AND TRUNCATED FORMS OF MURINE C-MYB PROTEINS

RG RAMSAY, S ISHII, Y NISHINA, G SOE, TJ GONDA

Journal article  |  1989  |  Oncogene Research

INDUCTION OF TRANSFORMED-CELLS TO TERMINAL DIFFERENTIATION

PA MARKS, M SHEFFERY, R RAMSAY, K IKEDA, RA RIFKIND

Journal article  |  1987  |  Annals of the New York Academy of Sciences

Changes in gene expression during hexamethylene bisacetamide induced erythroleukemia differentiation.

PA Marks, R Ramsay, M Sheffery, RA Rifkind

Journal article  |  1987  |  Progress in clinical and biological research

HMBA induces MELC to terminal erythroid differentiation. The mechanism of HMBA action is not known. Culture with HMBA causes chang..

CHANGES IN GENE-EXPRESSION ASSOCIATED WITH INDUCED-DIFFERENTIATION OF ERYTHROLEUKEMIA - PROTOONCOGENES, GLOBIN GENES, AND CELL-DIVISION

RG RAMSAY, K IKEDA, RA RIFKIND, PA MARKS

Journal article  |  1986  |  Proceedings of the National Academy of Sciences

SENSITIVITY TO ULTRAVIOLET-RADIATION IN A DOMINANTLY INHERITED FORM OF XERODERMA-PIGMENTOSUM

FP IMRAY, A HOCKEY, W RELF, RG RAMSAY, C KIDSON

Journal article  |  1986  |  Journal of Medical Genetics

FAMILIAL MELANOMA ASSOCIATED WITH DOMINANT ULTRAVIOLET-RADIATION SENSITIVITY

RG RAMSAY, P CHEN, FP IMRAY, C KIDSON, MF LAVIN, A HOCKEY

Journal article  |  1982  |  Cancer Research

Optimizing DNA Vaccines Against Nuclear Oncogenes

Sandra Carpinteri

Journal article  |  ImmunoGastroenterology

Inflammation and APC Mutation: the Perfect Storm for the Initiation of Colon Cancer

Robert G Ramsay

Journal article  |  Immuno-gastroenterology