Graham Baldwin

Zinc Preconditioning Provides Cytoprotection following Iodinated Contrast Media Exposure in In Vitro Models

Marlon Perera, Joseph Ischia, Damien Bolton, Arthur Shulkes, Graham S Baldwin, Oneel Patel

Journal article  |  2021  |  CONTRAST MEDIA & MOLECULAR IMAGING

Methods: Normal human proximal renal kidney cells (HK-2) were preconditioned with either increasing doses of ZnCl2 or control. Fol..

Public Attitudes, Behaviors, and Beliefs Related to COVID-19, Stay-at-Home Orders, Nonessential Business Closures, and Public Health Guidance - United States, New York City, and Los Angeles, May 5-12, 2020

Mark E Czeisler, Michael A Tynan, Mark E Howard, Sally Honeycutt, Erika B Fulmer, Daniel P Kidder, Rebecca Robbins, Laura K Barger, Elise R Facer-Childs, Grant Baldwin, Shantha MW Rajaratnam, Charles A Czeisler

Journal article  |  2020  |  MMWR-MORBIDITY AND MORTALITY WEEKLY REPORT

SARS-CoV-2, the virus that causes coronavirus disease 2019 (COVID-19), is thought to be transmitted mainly by person-to-person con..

Experimental rat models for contrast-induced nephropathy; A comprehensive review

M Perera, J Ischia, D Bolton, A Shulkes, GS Baldwin, O Patel

Journal article  |  2020  |  Journal of Nephropathology

Contrast-induced nephropathy (CIN) is an iatrogenic disease caused by the parenteral administration of iodinated contrast media (C..

Zinc preconditioning protects against renal ischaemia-reperfusion injury through manipulation of key metabolic pathways

D O'kane, G Baldwin, D Bolton, O Patel, J Ischia

Conference Proceedings  |  2020  |  BJU INTERNATIONAL

Inhibition of PAK1 suppresses pancreatic cancer by stimulation of anti-tumour immunity through down-regulation of PD-L1

Kai Wang, Yifan Zhan, Huynh Nhi, Chelsea Dumesny, Xiao Wang, Khashayer Asadi, David Herrmann, Paul Timpson, Yang Yang, Katrina Walsh, Graham S Baldwin, Mehrdad Nikfarjam, Hong He

Journal article  |  2020  |  CANCER LETTERS

Immunotherapies have not yielded significant clinical benefits for pancreatic ductal adenocarcinoma (PDA) because of the existence..

Preconditioning against renal ischaemia reperfusion injury: the failure to translate to the clinic

Dermot O'Kane, Graham S Baldwin, Damien M Bolton, Joseph J Ischia, Oneel Patel

Journal article  |  2019  |  JOURNAL OF NEPHROLOGY

Acute kidney injury (AKI) as a result of ischaemia-reperfusion represents a major healthcare burden worldwide. Mortality rates fro..

Metformin may offer no protective effect in men undergoing external beam radiation therapy for prostate cancer

Weranja KB Ranasinghe, Scott Williams, Joseph Ischia, David Wetherell, Graham Baldwin, Arthur Shulkes, Shomik Sengupta, Damien Bolton, Oneel Patel

Conference Proceedings  |  2019  |  BJU INTERNATIONAL

OBJECTIVES: To assess whether metformin reduces radio-resistance and increases survival in men undergoing external beam radiation ..

Antitumor effects of all-trans retinoic acid and its synergism with gemcitabine are associated with downregulation of p21-activated kinases in pancreatic cancer

Kai Wang, Graham S Baldwin, Mehrdad Nikfarjam, Hong He

Journal article  |  2019  |  AMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGY

Pancreatic ductal adenocarcinoma (PDA) is one of the most lethal malignancies worldwide. All-trans retinoic acid (ATRA) has been u..

Zinc protects the kidney against ischaemia-reperfusion injury: investigating the mechanisms of protection in wild-type and genetic-knockout murine strains

D O'Kane, J Du Plessis, A Shulkes, G Baldwin, D Bolton, J Ischia, O Patel

Conference Proceedings  |  2019  |  BJU INTERNATIONAL

MP70-11 ZINC PRECONDITIONING PROTECTS THE KIDNEY AGAINST ISCHAEMIA-REPERFUSION INJURY

Dermot O‘Kane*, Justin Du Plessis, Graham Baldwin, Arthur Shulkes, Damien Bolton, Oneel Patel, Joseph Ischia

Journal article  |  2019  |  Journal of Urology