Shaun Brennecke

The placenta is the villain or victim in the pathogenesis of pre-eclampsia

P Murthi, SP Brennecke

Journal article  |  2020  |  BJOG An International Journal of Obstetrics & Gynaecology

Decidual mesenchymal stem/stromal cell-derived extracellular vesicles ameliorate endothelial cell proliferation, inflammation, and oxidative stress in a cell culture model of preeclampsia

Shixuan Zheng, Aiwu Shi, Sophia Hill, Claire Grant, Maria I Kokkinos, Padma Murthi, Harry M Georgiou, Shaun P Brennecke, Bill Kalionis

Journal article  |  2020  |  Pregnancy Hypertension

Oxidative stress and endothelial dysfunction contribute substantially to the pathogenesis of preeclampsia (PE). Decidual mesenchym..

Functional changes in decidual mesenchymal stem/stromal cells are associated with spontaneous onset of labour

Joan C Wijaya, Ramin Khanabdali, Harry M Georgiou, Maria Kokkinos, Patrick F James, Shaun P Brennecke, Bill Kalionis

Journal article  |  2020  |  Molecular Human Reproduction

Ageing and parturition share common pathways, but their relationship remains poorly understood. Decidual cells undergo ageing as p..

NO placental inflammation

Helena C Parkington, Penelope M Sheehan, Harold A Coleman, Shaun P Brennecke

Journal article  |  2020  |  The Journal of Physiology

Preterm birth prediction in asymptomatic women at mid-gestation using a panel of novel protein biomarkers: the Prediction of PreTerm Labor (PPeTaL) study.

San Min Leow, Megan KW Di Quinzio, Zhen Long Ng, Claire Grant, Tal Amitay, Ying Wei, Moshe Hod, Penelope M Sheehan, Shaun P Brennecke, Nir Arbel, Harry M Georgiou

Journal article  |  2020  |  American Journal of Obstetrics and Gynecology MFM

BACKGROUND: Accurate prediction of spontaneous preterm labor/preterm birth in asymptomatic women remains an elusive clinical chall..

Prediction of preterm pre-eclampsia at midpregnancy using a multivariable screening algorithm

Carin Black, Daniel Lorber Rolnik, Ahmed Al-Amin, Stefan C Kane, Caroline Stolarek, Adrienne White, Fabricio Da Silva Costa, Shaun Brennecke

Journal article  |  2020  |  Australian and New Zealand Journal of Obstetrics and Gynaecology

BACKGROUND: Competing risk models used for midpregnancy prediction of preterm pre-eclampsia have shown detection rates (DR) of 85%..

New Insights into the Nature and Role of Potassium Channels in Regulating Uterine Contraction in Human Labour.

Ranga Siriwardhana, Mary A Tonta, Penelope M Sheehan, Harold A Coleman, Shaun P Brennecke, Helena C Parkington

Conference Proceedings  |  2020  |  REPRODUCTIVE SCIENCES

Early Pregnancy Screening for Women at High-Risk of GDM Results in Reduced Neonatal Morbidity and Similar Maternal Outcomes to Routine Screening

Erin Clarke, Thomas J Cade, Shaun P Brennecke

Journal article  |  2020  |  Journal of Pregnancy

The Australasian Diabetes in Pregnancy Society recommends screening high-risk women for gestational diabetes mellitus (GDM) before..

Opportunities for improving hypertensive disorders of pregnancy (HDP) management in primary care settings: A review of international published guidelines in the context of pregnancy care in Indonesia

Fitriana Murriya Ekawati, Ova Emilia, Shaun Brennecke, Jane Gunn, Sharon Licqurish, Phyllis Lau

Journal article  |  2020  |  Pregnancy Hypertension

Almost all of global maternal mortality caused by HDP occurs in low to middle-income countries (LMIC). However, limited guidance i..

Optic nerve sonography and ophthalmic artery Doppler velocimetry in healthy pregnant women: an Australian cohort study

Stefan C Kane, Alicia T Dennis, Fabricio Da Silva Costa, Louise H Kornman, Thomas J Cade, Shaun P Brennecke

Journal article  |  2019  |  Journal of Clinical Ultrasound

PURPOSE: Maternal ocular sonography offers a window into cerebrovascular and intracranial pressure changes in pregnancy. This stud..