Laila Huq

Molecular Interactions of Peptide Encapsulated Calcium Phosphate Delivery Vehicle at Enamel Surfaces

NL Huq, KJ Cross, H Myroforidis, DP Stanton, YY Chen, BR Ward, EC Reynolds

Book Chapter  |  2018

Phosphorylated peptides derived from milk caseins, known as casein phosphopeptides (CPP) self-assemble and encapsulate the calcium..

Porphyromonas gingivalis Gingipains Display Transpeptidation Activity

Lianyi Zhang, Paul D Veith, N Laila Huq, Yu-Yen Chen, Christine A Seers, Keith J Cross, Dhana G Gorasia, Eric C Reynolds

Journal article  |  2018  |  Journal of Proteome Research

Interplay between Porphyromonas gingivalis and EGF signalling in the regulation of CXCL14

Jiamin Aw, Glen M Scholz, Noorjahan Laila Huq, Jennifer Huynh, Neil M O'Brien-Simpson, Eric C Reynolds

Journal article  |  2018  |  Cellular Microbiology

Physico-chemical Characterisation of the Processes Involved in Enamel Remineralisation by CPP-ACP

Keith Cross, Noorjahan Laila Huq, Boon Loh, Li-Ming Bhutta, Bill Madytianos, Sarah Peterson, David Phillip Stanton, Yi Yuan, Coralie Reynolds, Glen Walker, Peiyan Shen, Eric Charles Reynolds

Book Chapter  |  2018

Casein Phosphopeptide-Amorphous Calcium Phosphate Reduces Streptococcus mutans Biofilm Development on Glass Ionomer Cement and Disrupts Established Biofilms

Stuart G Dashper, Deanne V Catmull, Sze-Wei Liu, Helen Myroforidis, Ilya Zalizniak, Joseph EA Palamara, N Laila Huq, Eric C Reynolds

Journal article  |  2016  |  PLOS ONE

Casein Phosphopeptide-Amorphous Calcium Phosphate Nanocomplexes: A Structural Model

Keith J Cross, N Laila Huq, Eric C Reynolds

Journal article  |  2016  |  Biochemistry

The Interactions of CPP-ACP with Saliva

Noorjahan Laila Huq, Helen Myroforidis, Keith J Cross, David P Stanton, Paul D Veith, Brent R Ward, Eric C Reynolds

Journal article  |  2016  |  International Journal of Molecular Sciences

Bioinformatic investigation of the cost management strategies of five oral microbes

KJ Cross, NL Huq, SH Park, JS Park, P Pham, M Quah, M Ranjan, EC Reynolds

Journal article  |  2015  |  Molecular Oral Microbiology

Structure of the lysine specific protease Kgp from Porphyromonas gingivalis, a target for improved oral health

Michael A Gorman, Christine A Seers, Belinda J Michell, Susanne C Feil, N Laila Huq, Keith J Cross, Eric C Reynolds, Michael W Parker

Journal article  |  2015  |  Protein Science

Propeptide-Mediated Inhibition of Cognate Gingipain Proteinases

N Laila Huq, Christine A Seers, Elena CY Toh, Stuart G Dashper, Nada Slakeski, Lianyi Zhang, Brent R Ward, Vincent Meuric, Dina Chen, Keith J Cross, Eric C Reynolds

Journal article  |  2013  |  PLoS One

Inhibitors of the cell-surface proteinases of the periodontal pathogen Porphyromonas gingivalis

NL Huq, CA Seers, SG Dashper, KJ Cross, EC Reynolds

Book Chapter  |  2013

Inhibition of proteolytic activity of periodontal pathogens by casein-derived peptides

Elena CY Toh, Stuart G Dashper, N Laila Huq, Troy J Attard, Keith J Cross, David P Stanton, Eric C Reynolds

Journal article  |  2012  |  International Dairy Journal

A bio-informatics study of the c25 cysteine protease family

K J. Cross, N L. Huq, E C. Reynolds

Journal article  |  2012  |  Open Journal of Genetics

Porphyromonas gingivalis Cysteine Proteinase Inhibition by kappa-Casein Peptides

Elena CY Toh, Stuart G Dashper, N Laila Huq, Troy J Attard, Neil M O'Brien-Simpson, Yu-Yen Chen, Keith J Cross, David P Stanton, Rita A Paolini, Eric C Reynolds

Journal article  |  2011  |  Antimicrobial Agents and Chemotherapy

Cysteine Protease Inhibitors: from Evolutionary Relationships to Modern Chemotherapeutic Design for the Treatment of Infectious Diseases

ECY Toh, NL Huq, SG Dashper, EC Reynolds

Journal article  |  2010  |  Current Protein and Peptide Science

New Approaches to Enhanced Remineralization of Tooth Enamel

NJ Cochrane, F Cai, NL Huq, MF Burrow, EC Reynolds

Journal article  |  2010  |  Journal of Dental Research

A simplified quantitative test-adapted Checkbuf test-for resting saliva buffering capacity compared with a standard test

Yuichi Kitasako, Michael F Burrow, Laila N Huq, Margaret A Stacey, Eric C Reynolds, Junji Tagami

Journal article  |  2009  |  Oral Surgery, Oral Medicine, Oral Pathology, Oral Radiology, and Endodontics

Comparative analysis of three commercial saliva testing kits with a standard saliva buffering test

Y Kitasako, MF Burrow, M Stacey, L Huq, EC Reynolds, J Tagami

Journal article  |  2008  |  Australian Dental Journal

Synthesis and characterisation of a multiphosphorylated phosphophoryn repeat motif; H-[Asp-(Ser(P))(2)](3)-Asp-OH

Neil M O'Brien-Simpson, Troy J Attard, Ashwini Loganathan, N Laila Huq, Keith J Cross, Peter F Riley, Eric C Reynolds

Journal article  |  2007  |  International Journal of Peptide Research and Therapeutics

The role of multiphosphorylated peptides in mineralized tissue regeneration

Keith J Cross, N Laila Huq, Neil M O'Brien-Simpson, John W Perich, Troy J Attard, Eric C Reynolds

Journal article  |  2007  |  International Journal of Peptide Research and Therapeutics

A review of the salivary proteome and peptidome and saliva-derived peptide therapeutics

N Laila Huq, Keith J Cross, Men Ung, Helen Myroforidis, Paul D Veith, Dina Chen, David Stanton, Huiling He, Brent R Ward, Eric C Reynolds

Journal article  |  2007  |  International Journal of Peptide Research and Therapeutics

The Role of Multiphosphorylated Peptides in Mineralized Tissue Regeneration

Keith J Cross, N Laila Huq, Neil M O’Brien-Simpson, John W Perich, Troy J Attard, Eric C Reynolds

Journal article  |  2007  |  International Journal of Peptide Research and Therapeutics

Casein phosphopeptides in oral health - Chemistry and clinical applications

KJ Cross, NL Huq, EC Reynolds

Journal article  |  2007  |  Current Pharmaceutical Design

Anticariogenic Peptides

K CROSS, N HUQ, E REYNOLDS

Book Chapter  |  2006

Association of bovine dentine phosphophoryn with collagen fragments

NL Huq, A Loganathan, KJ Cross, YY Chen, NI Johnson, M Willetts, PD Veith, EC Reynolds

Journal article  |  2005  |  Archives of Oral Biology

Protein dynamics of bovine dentin phosphophoryn

KJ Cross, NL Huq, EC Reynolds

Journal article  |  2005  |  Journal of Peptide Research

A review of protein structure and gene organisation for proteins associated with mineralised tissue and calcium phosphate stabilisation encoded on human chromosome 4

NL Huq, KJ Cross, M Ung, EC Reynolds

Journal article  |  2005  |  Archives of Oral Biology

Physicochemical characterization of casein phosphopeptide-amorphous calcium phosphate nanocomplexes

KJ Cross, NL Huq, JE Palamara, JW Perich, EC Reynolds

Journal article  |  2005  |  Journal of Biological Chemistry

NMR studies of a novel calcium, phosphate and fluoride delivery vehicle-alpha(S1)-casein(59-79) by stabilized amorphous calcium fluoride phosphate nanocomplexes

KJ Cross, NL Huq, DP Stanton, M Sum, EC Reynolds

Journal article  |  2004  |  Biomaterials

Molecular modelling of the multiphosphorylated casein phosphopeptide alpha(S1)-casein(59-79) based on NMR constraints

NL Huq, KJ Cross, EC Reynolds

Journal article  |  2004  |  Journal of Dairy Research

Whole and parotid saliva - protein profiles as separated on 5-20% SDS-polyacrylamide gradient gel electro-phoresis and using maldi-tof mass spectrometry

N HUQ, A DeAngelis, ZHA Rahim, M UNG, J Lucas, K CROSS, E REYNOLDS

Journal article  |  2004  |  Annals of Dentistry

Synthesis of casein peptide analogues and their calcium binding affinities.

TJ Attard, NO Simpson, NL Huq, KJ Cross, EC Reynolds

Conference Proceedings  |  2003  |  JOURNAL OF DENTAL RESEARCH

NMR spectroscopy and mass spectrometry studies of a novel calcium, phosphate and fluoride delivery vehicle - the multiphosphorylated peptide alpha(SI)-Casein(59-79) complexed with amorphous calcium fluoride phosphate.

KJ Cross, NL Huq, D Stanton, M Sum, EC Reynolds

Conference Proceedings  |  2003  |  JOURNAL OF DENTAL RESEARCH

Investigation of the binding of casein phosphopeptides to the major enamel pellicle proteins.

M Ung, NL Huq, KJ Cross, EC Reynolds

Conference Proceedings  |  2003  |  JOURNAL OF DENTAL RESEARCH

Conserved chromosomal synteny exhibited by dentine, enamel, bone and milk proteins on human chromosome 4.

NL Huq, KJ Cross, EC Reynolds

Conference Proceedings  |  2003  |  JOURNAL OF DENTAL RESEARCH

Molecular modelling of the anticariogenic casein phosphopeptide alpha(S2)-CN(2-20) using NMR spectroscopy derived constraints.

A DeAngelis, NL Huq, KJ Cross, EC Reynolds

Conference Proceedings  |  2003  |  JOURNAL OF DENTAL RESEARCH

Nascent helix in the multiphosphorylated peptide (alpha)(S2)-casein(2-20)

NL Huq, KJ Cross, EC Reynolds

Journal article  |  2003  |  Journal of Peptide Science

NMR Spectroscopy and mass spectroscopic studies of a novel calcium, phosphate and fluoride delivery vehicle-the multiphosphorylated peptide αs2-Casein(59-79) complexed with amorphous calcium fluoride phosphate.

K CROSS, N HUQ, D STANTON, MM SUM, E REYNOLDS

Journal article  |  2003  |  Journal of Dental Research

Cation-dependent structural features of beta-casein-(1-25)

KJ Cross, NL Huq, W Bicknell, EC Reynolds

Journal article  |  2001  |  Biochemical Journal

N-terminal sequence analysis of bovine dentin phosphophoryn after conversion of phosphoseryl to S-propylcysteinyl residues

NL Huq, KJ Cross, GH Talbo, PF Riley, A Loganathan, MA Crossley, JW Perich, EC Reynolds

Journal article  |  2000  |  Journal of Dental Research

Molecular modelling of a multiphosphorylated sequence motif bound to hydroxyapatite surfaces

NL Huq, KJ Cross, EC Reynolds

Journal article  |  2000  |  JOURNAL OF MOLECULAR MODELING

Epitope analysis of the multiphosphorylated peptide alpha(s1)-casein(59-79)

JW Perich, CL Black, NL Huq, EC Reynolds

Journal article  |  1999  |  Journal of Peptide Science

Epitope analysis of the multiphosphorylated peptide alpha s1-casein (59-79).

JW Perich, CL Black, NL Huq, EC Reynolds

Journal article  |  1999  |  Journal of Peptide Science

The multiphosphorylated tryptic peptide alpha(s1)-casein(59-79) has been shown to be antigenic with anti-casein antibodies. In an ..

Advances in enamel remineralization: Casein phosphopeptide-amorphous calcium phosphate

EC Reynolds, CL Black, F Cai, KJ Cross, D Eakins, NL Huq, MV Morgan, A Nowicki, JW Perich, PF Riley, P Shen, G Talbo, F Webber

Journal article  |  1999  |  Journal of Clinical Dentistry

Molecular modelling of multi-phosphorylated sequence motifs on calcium phosphate surfaces.

L Huq, KJ Cross, EC Reynolds

Conference Proceedings  |  1997  |  JOURNAL OF DENTAL RESEARCH

Molecular modelling of casein phosphopeptides in the presence of calcium ions.

KJ Cross, L Huq, W Bicknell, EC Reynolds

Conference Proceedings  |  1997  |  JOURNAL OF DENTAL RESEARCH

A high-field (1)HNMR study of the casein phosphopeptide beta-casein(1-25).

NL Huq, KJ Cross, EC Reynolds

Conference Proceedings  |  1996  |  JOURNAL OF DENTAL RESEARCH

Predicted structure of the adenosylcobalamin-binding domain of methylmalonyl-CoA mutase.

CA Jackson, NL Huq, EC Reynolds

Conference Proceedings  |  1996  |  JOURNAL OF DENTAL RESEARCH

Purification and N-terminal sequence analysis of bovine dentine phosphophoryn.

MA Crossley, NL Huq, L Kirszbaum, EC Reynolds

Conference Proceedings  |  1996  |  JOURNAL OF DENTAL RESEARCH

A 1H-NMR study of the casein phosphopeptide alpha s1-casein(59-79).

NL Huq, KJ Cross, EC Reynolds

Journal article  |  1995  |  Biochimica et Biophysica Acta (BBA) - Protein Structure and Molecular Enzymology

Complete sequence-specific resonance assignments have been determined for a calcium phosphate sequestering, phosphoseryl-containin..

A H-1-NMR STUDY OF THE CASEIN PHOSPHOPEPTIDE (ALPHA(S1)-CASEIN(59-79)

NL HUQ, KJ CROSS, EC REYNOLDS

Journal article  |  1995  |  BIOCHIMICA ET BIOPHYSICA ACTA-PROTEIN STRUCTURE AND MOLECULAR ENZYMOLOGY

COMPLETE AMINO-ACID-SEQUENCE AND 3-D MODEL OF HPR FROM STREPTOCOCCUS-MUTANS

L KIRSZBAUM, L HUQ, SG DASHPER, PF RILEY, EC REYNOLDS

Conference Proceedings  |  1995  |  JOURNAL OF DENTAL RESEARCH

A STUDY OF THE CONFORMATION OF THE ANTICARIOGENIC CASEIN PHOSPHOPEPTIDE ALPHA-S1-CASEIN(59-79)

NL HUQ, KJ CROSS, EC REYNOLDS

Conference Proceedings  |  1995  |  JOURNAL OF DENTAL RESEARCH

A 1HNMR STUDY OF THE CASEIN PHOSPHOPEPTIDE ALPHA(S)2-CASEIN(1-21)

NL HUQ, KJ CROSS, DP STANTON, EC REYNOLDS

Conference Proceedings  |  1995  |  JOURNAL OF DENTAL RESEARCH

COMPLETE AMINO-ACID-SEQUENCE AND COMPARATIVE MOLECULAR MODELING OF HPR FROM STREPTOCOCCUS-MUTANS INGBRITT

SG DASHPER, L KIRSZBAUM, NL HUQ, PF RILEY, EC REYNOLDS

Journal article  |  1994  |  Biochemical and Biophysical Research Communications

ELECTROCHEMICAL INVESTIGATIONS OF POPLAR, SPINACH, CUCUMBER, AND PARSLEY PLASTOCYANINS AT CONVENTIONAL AND MICROSIZED CARBON ELECTRODES

FN BUCHI, AM BOND, R CODD, LN HUQ, HC FREEMAN

Journal article  |  1992  |  Inorganic Chemistry

RESONANCE RAMAN-SPECTRA OF PLASTOCYANIN AND PSEUDOAZURIN - EVIDENCE FOR CONSERVED CYSTEINE LIGAND CONFORMATIONS IN CUPREDOXINS (BLUE COPPER PROTEINS)

J HAN, ET ADMAN, T BEPPU, R CODD, HC FREEMAN, L HUQ, TM LOEHR, J SANDERSLOEHR

Journal article  |  1991  |  Biochemistry

PARTIAL AMINO-ACID-SEQUENCE OF OSTEOCALCIN FROM AN EXTINCT SPECIES OF RATITE BIRD

NL HUQ, A TSENG, GE CHAPMAN

Journal article  |  1990  |  Biochemistry International

RECOVERY FROM STEROID-INDUCED OSTEOPOROSIS

NA POCOCK, JA EISMAN, CR DUNSTAN, RA EVANS, DH THOMAS, NL HUQ

Journal article  |  1987  |  Annals of Internal Medicine

THE AMINO-ACID-SEQUENCE OF EMU OSTEOCALCIN - GAS-PHASE SEQUENCING OF GLA-CONTAINING PROTEINS

NL HUQ, A TSENG, GE CHAPMAN

Journal article  |  1987  |  Biochemistry international

METHIONINE OXIDATION IN HUMAN GROWTH-HORMONE AND HUMAN CHORIONIC SOMATOMAMMOTROPIN - EFFECTS ON RECEPTOR-BINDING AND BIOLOGICAL-ACTIVITIES

LC TEH, LJ MURPHY, NL HUQ, AS SURUS, HG FRIESEN, L LAZARUS, GE CHAPMAN

Journal article  |  1987  |  Journal of Biological Chemistry

LOW SERUM OSTEOCALCIN LEVELS IN GLUCOCORTICOID-TREATED ASTHMATICS

IR REID, GE CHAPMAN, TRC FRASER, AD DAVIES, AS SURUS, J MEYER, NL HUQ, HK IBBERTSON

Journal article  |  1986  |  The Journal of Clinical Endocrinology & Metabolism

IMMUNOCHEMICAL DETECTION AND CHARACTERIZATION OF OSTEOCALCIN FROM MOA BONE

NL HUQ, SM RAMBAUD, LC TEH, AD DAVIES, B MCCULLOCH, MM TROTTER, GE CHAPMAN

Journal article  |  1985  |  Biochemical and Biophysical Research Communications

THE AMINO-ACID-SEQUENCES OF GOAT, PIG AND WALLABY OSTEOCALCINS

NL HUQ, LC TEH, DL CHRISTIE, GE CHAPMAN

Journal article  |  1984  |  Biochemistry International

PRIMARY STRUCTURE OF OSTEOCALCIN FROM OVINE BONE - DABITC SEQUENCING OF 4-HYDROXYPROLINE AND GAMMA-CARBOXYGLUTAMATE RESIDUES

LM MENDE, NL HUQ, HR MATTHEWS, GE CHAPMAN

Journal article  |  1984  |  International Journal of Peptide and Protein Research