Bernard Yan

Correlation between CT angiography and digital subtraction angiography in acute ischemic strokes.

Su Jin Lee, Belinda Liu, Neil Rane, Peter Mitchell, Richard Dowling, Bernard Yan

Journal article  |  2021  |  Clinical Neurology and Neurosurgery

OBJECTIVE: CT angiography (CTA) is not necessarily performed for all acute ischemic strokes due to variations in national guidelin..

Patterns of Infarction on MRI in Patients With Acute Ischemic Stroke and Cardio-Embolism: A Systematic Review and Meta-Analysis

Angelos Sharobeam, Leonid Churilov, Mark Parsons, Geoffrey A Donnan, Stephen M Davis, Bernard Yan

Journal article  |  2020  |  Frontiers in Neurology

Background: Cardioembolic strokes are common however atrial fibrillation, the most common cause, is often asymptomatic and difficu..

Reduced Impact of Endovascular Thrombectomy on Disability in Real-World Practice, Relative to Randomized Controlled Trial Evidence in Australia

Lan Gao, Elise Tan, Marj Moodie, Mark Parsons, Neil J Spratt, Christopher Levi, Kenneth Butcher, Timothy Kleinig, Bernard Yan, Chushuang Chen, Longting Lin, Philip Choi, Andrew Bivard

Journal article  |  2020  |  Frontiers in Neurology

Background and Aims: Disability-adjusted life years (DALYs) are an important measure of the global burden of disease that informs ..

Tranexamic acid in patients with intracerebral haemorrhage (STOP-AUST): a multicentre, randomised, placebo-controlled, phase 2 trial

Atte Meretoja, Nawaf Yassi, Teddy Y Wu, Leonid Churilov, Gerli Sibolt, Jiann-Shing Jeng, Timothy Kleinig, Neil J Spratt, Vincent Thijs, Tissa Wijeratne, Der-Yang Cho, Darshan Shah, Geoffrey C Cloud, Phan Thanh, Christopher Bladin, Andrew Moey, Richard I Aviv, Christen D Barras, Gagan Sharma, Chung Y Hsu, et al.

Journal article  |  2020  |  The Lancet Neurology

BACKGROUND: Despite intracerebral haemorrhage causing 5% of deaths worldwide, few evidence-based therapeutic strategies other than..

Cost-Effectiveness of Tenecteplase Before Thrombectomy for Ischemic Stroke

Lan Gao, Marj Moodie, Peter J Mitchell, Leonid Churilov, Timothy J Kleinig, Nawaf Yassi, Bernard Yan, Mark W Parsons, Geoffrey A Donnan, Stephen M Davis, Bruce CV Campbell

Journal article  |  2020  |  Stroke

BACKGROUND AND PURPOSE: Tenecteplase improved functional outcomes and reduced the requirement for endovascular thrombectomy in isc..

Intravenous alteplase for stroke with unknown time of onset guided by advanced imaging: systematic review and meta-analysis of individual patient data

Goetz Thomalla, Florent Boutitie, Henry Ma, Masatoshi Koga, Peter Ringleb, Lee H Schwamm, Ona Wu, Martin Bendszus, Christopher F Bladin, Bruce CV Campbell, Bastian Cheng, Leonid Churilov, Martin Ebinger, Matthias Endres, Jochen B Fiebach, Mayumi Fukuda-Doi, Manabu Inoue, Timothy J Kleinig, Lawrence L Latour, Robin Lemmens, et al.

Journal article  |  2020  |  The Lancet

BACKGROUND: Patients who have had a stroke with unknown time of onset have been previously excluded from thrombolysis. We aimed to..

Association of Reperfusion After Thrombolysis With Clinical Outcome Across the 4.5-to 9-Hours and Wake-Up Stroke Time Window A Meta-Analysis of the EXTEND and EPITHET Randomized Clinical Trials

Bruce CV Campbell, Henry Ma, Mark W Parsons, Leonid Churilov, Nawaf Yassi, Timothy J Kleinig, Chung Y Hsu, Helen M Dewey, Kenneth S Butcher, Bernard Yan, Patricia M Desmond, Tissa Wijeratne, Sami Curtze, P Alan Barber, Deidre A De Silva, Vincent Thijs, Christopher R Levi, Christopher F Bladin, Gagan Sharma, Andrew Bivard, et al.

Journal article  |  2020  |  JAMA Neurology

Importance: Intravenous alteplase reduces disability after ischemic stroke in patients 4.5 to 9 hours after onset and with wake-up..

Endovascular Therapy in Mild Ischemic Strokes Presenting Under 6 hours: An International Survey

Nastajjia A Krementz, Avi Landman, Hannah E Gardener, Antonio Arauz, Anny D Rodriguez, Hershel Cannon, H Lee Lau, Nicole Sur, Erika Marulanda-Londono, Dileep R Yavagal, Bernard Yan, Simon Nagel, Andrew M Demchuk, Pooja Khatri, Jose G Romano, Negar Asdaghi

Journal article  |  2020  |  Journal of Stroke and Cerebrovascular Diseases

BACKGROUND: Endovascular therapy (EVT) for patients with mild ischemic stroke (NIHSS ≤5) and visible intracranial occlusion remain..

Implementation of regional Acute Stroke Care Map increases thrombolysis rates for acute ischaemic stroke in Chinese urban area in only 3 months.

Yi Sui, Jianfeng Luo, Chunyao Dong, Liqiang Zheng, Weijin Zhao, Yao Zhang, Ying Xian, Huaguang Zheng, Bernard Yan, Mark Parsons, Li Ren, Ying Xiao, Haoyue Zhu, Lijie Ren, Qi Fang, Yi Yang, Weidong Liu, Bing Xu

Journal article  |  2020  |  Stroke and Vascular Neurology

BACKGROUND: The rate of intravenous thrombolysis for acute ischaemic stroke remains low in China. We investigated whether the impl..

Novel Measures of Similarity and Asymmetry in Upper Limb Activities for Identifying Hemiparetic Severity in Stroke Survivors.

Shreyasi Datta, Chandan Karmakar, Bernard Yan, Marimuthu Swami Palaniswami

Journal article  |  2020  |  IEEE Journal of Biomedical and Health Informatics

Stroke survivors are often characterized by hemiparesis, i.e., paralysis in one half of the body, severely affecting upper limb mo..