Find out more about Janetta Culvenor's experience
Janetta Culvenor's highlights
Janetta Culvenor's selected work
Clioquinol Improves Cognitive, Motor Function, and Microanatomy of the Alpha-Synuclein hA5..
Clioquinol Improves Cognitive, Motor Function, and Microanatomy of the Alpha-Synuclein hA5..
Displaying the 10 most recent projects by Janetta Culvenor.
Internal Research Grant
Displaying the 43 most recent scholarly works by Janetta Culvenor.
The Roc-COR tandem domain of leucine-rich repeat kinase 2 forms dimers and exhibits conventional Ras-like GTPase properties
Ryan D Mills, Lung-Yu Liang, Daisy Sio-Seng Lio, Yee-Foong Mok, Terrence D Mulhern, George Cao, Michael Griffin, Vijaya B Kenche, Janetta G Culvenor, Heung-Chin Cheng
Journal article | 2018 | Journal of Neurochemistry
Clioquinol Improves Cognitive, Motor Function, and Microanatomy of the Alpha-Synuclein hA53T Transgenic Mice
David I Finkelstein, Dominic J Hare, Jessica L Billings, Amelia Sedjahtera, Milawaty Nurjono, Elisa Arthofer, Sonia George, Janetta G Culvenor, Ashley I Bush, Paul A Adlard
Journal article | 2016 | ACS chemical neuroscience
Prediction of the Repeat Domain Structures and Impact of Parkinsonism-Associated Variations on Structure and Function of all Functional Domains of Leucine-Rich Repeat Kinase 2 (LRRK2)
Ryan D Mills, Terrence D Mulhern, Fei Liu, Janetta G Culvenor, Heung-Chin Cheng
Journal article | 2014 | HUMAN MUTATION
Mild Oxidative Stress Induces Redistribution of BACE1 in Non-Apoptotic Conditions and Promotes the Amyloidogenic Processing of Alzheimer's Disease Amyloid Precursor Protein
Jiang-Li Tan, Qiao-Xin Li, Giuseppe D Ciccotosto, Peter John Crouch, Janetta Gladys Culvenor, Anthony Robert White, Genevieve Evin
Journal article | 2013 | PLOS ONE
The hypoxia imaging agent Cu-II(atsm) is neuroprotective and improves motor and cognitive functions in multiple animal models of Parkinson's disease
Lin W Hung, Victor L Villemagne, Lesley Cheng, Nicki A Sherratt, Scott Ayton, Anthony R White, Peter J Crouch, SinChun Lim, Su Ling Leong, Simon Wilkins, Jessica George, Blaine R Roberts, Chi LL Pham, Xiang Liu, Francis CK Chiu, David M Shackleford, Andrew K Powell, Colin L Masters, Ashley I Bush, Graeme O'Keefe, et al.
Journal article | 2012 | JOURNAL OF EXPERIMENTAL MEDICINE
Changes in acetylcholinesterase expression are associated with altered presenilin-1 levels
Maria-Ximena Silveyra, Maria-Salud Garcia-Ayllon, Carol Serra-Basante, Valeria Mazzoni, Maria-Salud Garcia-Gutierrez, Jorge Manzanares, Janetta G Culvenor, Javier Saez-Valero
Journal article | 2012 | Neurobiology of Aging
Diacetylbis(N(4)-methylthiosemicarbazonato) Copper(II) (Cu-II(atsm)) Protects against Peroxynitrite-induced Nitrosative Damage and Prolongs Survival in Amyotrophic Lateral Sclerosis Mouse Model
Cynthia PW Soon, Paul S Donnelly, Bradley J Turner, Lin W Hung, Peter J Crouch, Nicki A Sherratt, Jiang-Li Tan, Nastasia K-H Lim, Linh Lam, Laura Bica, SinChun Lim, James L Hickey, Julia Morizzi, Andrew Powell, David I Finkelstein, Janetta G Culvenor, Colin L Masters, James Duce, Anthony R White, Kevin J Barnham, et al.
Journal article | 2011 | Journal of Biological Chemistry
Defining the Substrate Specificity Determinants Recognized by the Active Site of C-Terminal Src Kinase-Homologous Kinase (CHK) and Identification of beta-Synuclein as a Potential CHK Physiological Substrate
Kim K Ia, Grace R Jeschke, Yang Deng, Mohd Aizuddin Kamaruddin, Nicholas A Williamson, Denis B Scanlon, Janetta G Culvenor, Mohammed Iqbal Hossain, Anthony W Purcell, Sheng Liu, Hong-Jian Zhu, Bruno Catimel, Benjamin E Turk, Heung-Chin Cheng
Journal article | 2011 | BIOCHEMISTRY
Effect of Metal Chelators on γ-Secretase Indicates That Calcium and Magnesium Ions Facilitate Cleavage of Alzheimer Amyloid Precursor Substrate.
Michael Ho, David E Hoke, Yee Jia Chua, Qiao-Xin Li, Janetta G Culvenor, Colin Masters, Anthony R White, Geneviève Evin
Journal article | 2010 | International Journal of Alzheimer's Disease
Gamma-secretase is involved in the production of Aβ amyloid peptides. It cleaves the transmembrane domain of the amyloid precursor..
alpha-Synuclein Transgenic Mice Reveal Compensatory Increases in Parkinson's Disease-Associated Proteins DJ-1 and Parkin and Have Enhanced alpha-Synuclein and PINK1 Levels After Rotenone Treatment
Sonia George, Su San Mok, Milawaty Nurjono, Scott Ayton, David I Finkelstein, Colin L Masters, Qiao-Xin Li, Janetta G Culvenor
Journal article | 2010 | Journal of Molecular Neuroscience
Allosteric networks governing regulation and catalysis of Src-family protein tyrosine kinases: Implications for disease-associated kinases
Heung-Chin Cheng, Timothy M Johnson, Ryan D Mills, Yuh-Ping Chong, Khai-Chew Chan, Janetta G Culvenor
Journal article | 2010 | CLINICAL AND EXPERIMENTAL PHARMACOLOGY AND PHYSIOLOGY
Paradoxical Condensation of Copper with Elevated beta-Amyloid in Lipid Rafts under Cellular Copper Deficiency Conditions IMPLICATIONS FOR ALZHEIMER DISEASE
Ya Hui Hung, Elysia L Robb, Irene Volitakis, Michael Ho, Genevieve Evin, Qiao-Xin Li, Janetta G Culvenor, Colin L Masters, Robert A Cherny, Ashley I Bush
Journal article | 2009 | Journal of Biological Chemistry
SLC30A3 Responds to Glucose- and Zinc Variations in beta-Cells and Is Critical for Insulin Production and In Vivo Glucose-Metabolism During beta-Cell Stress
Kamille Smidt, Niels Jessen, Andreas Bronden Petersen, Agnete Larsen, Nils Magnusson, Johanne Bruun Jeppesen, Meredin Stoltenberg, Janetta G Culvenor, Andrew Tsatsanis, Birgitte Brock, Ole Schmitz, Lise Wogensen, Ashley I Bush, Jorgen Rungby
Journal article | 2009 | PLOS ONE
In vitro characterization of Pittsburgh compound-B binding to Lewy bodies
Michelle T Fodero-Tavoletti, David P Smith, Catriona A McLean, Paul A Adlard, Kevin J Barnham, Lisa E Foster, Laura Leone, Keyla Perez, Mikhalina Cortes, Janetta G Culvenor, Qiao-Xin Li, Katrina M Laughton, Christopher C Rowe, Colin L Masters, Roberto Cappai, Victor L Villemagne
Journal article | 2007 | Journal of Neuroscience
A comparative analysis of leucine-rich repeat kinase 2 (Lrrk2) expression in mouse brain and Lewy body disease
HL Melrose, CB Kent, JP Taylor, JC Dachsel, KM Hinkle, SJ Lincoln, SS Mok, JG Culvenor, CL Masters, GM Tyndall, DI Bass, Z Ahmed, CA Andorfer, OA Ross, ZK Wszolek, A Delldonne, DW Dickson, MJ Farrer
Journal article | 2007 | Neuroscience
C-terminal truncation and Parkinson's disease-associated mutations down-regulate the protein serine/threonine kinase activity of PTEN-induced kinase-1
Chou Hung Sim, Daisy Sio Seng Lio, Su San Mok, Colin L Masters, Andrew F Hill, Janetta G Culvenor, Heung-Chin Cheng
Journal article | 2006 | Human Molecular Genetics
Dopamine promotes α‐synuclein aggregation into SDS‐resistant soluble oligomers via a distinct folding pathway
Roberto Cappai, Su‐Ling Leck, Deborah J Tew, Nicholas A Williamson, David P Smith, Denise Galatis, Robyn A Sharpies, Cyril C Curtain, Feda' E Ali, Robert A Cherny, Janetta G Culvenor, Stephen P Bottomley, Colin L Masters, Kevin J Barnham, Andrew F Hill
Journal article | 2005 | FASEB Journal
Expression of truncated presenilin 2 splice variant in Alzheimer's disease, bipolar disorder, and schizophrenia brain cortex
MJ Smith, RA Sharples, G Evin, CA McLean, B Dean, G Pavey, E Fantino, RGH Cotton, K Imaizumi, CL Masters, R Cappai, JG Culvenor
Journal article | 2004 | Molecular Brain Research
Characterization of presenilin complexes from mouse and human brain using Blue Native gel electrophoresis reveals high expression in embryonic brain and minimal change in complex mobility with pathogenic presenilin mutations
JG Culvenor, NT Ilaya, MT Ryan, L Canterford, DE Hoke, NA Williamson, CA McLean, CL Masters, G Evin
Journal article | 2004 | European Journal of Biochemistry
Selecting cells with different Alzheimer's disease gamma-secretase activity using FACS - Differential effect of presenilin exon 9 deletion on gamma- and epsilon-cleavage
MF Sernee, G Evin, JG Culvenor, JA Villadangos, K Beyreuther, CL Masters, R Cappai
Journal article | 2003 | European Journal of Biochemistry
Modulation of Alzheimer's Disease Aβ pathways for rational therapeutic intervention: secretase inhibition and metalloprotein active compounds.
G EVIN, undefined Sernee, K BARNHAM, undefined Holsinger, J CULVENOR, D HOKE, Q LI, undefined Smith, C MAYNARD, N WILLIAMSON, G CICCOTOSTO, S MOK, I VOLITAKIS, G KOCAK, undefined Carrington, undefined Opazo, AK TICKLER, undefined Huang, undefined Beyreuther, R CAPPAI, et al.
Book Chapter | 2003
Alternative transcripts of presenilin-1 associated with frontotemporal dementia
Geneviève Evin, Margaret J Smith, Angela Tziotis, Catriona McLean, Louise Canterford, Robyn A Sharples, Roberto Cappai, Andreas Weidemann, Konrad Beyreuther, Richard GH Cotton, Colin L Masters, Janetta G Culvenor
Journal article | 2002 | NeuroReport
Platelet alpha- and gamma-synucleins in Parkinson's disease and normal control subjects
Qiao-Xin Li, Bruce C Campbell, Catriona A McLean, Domimic Thyagarajan, Wei-Ping Gai, Robert M Kapsa, Konrad Beyreuther, Colin L Masters, Janetta G Culvenor
Journal article | 2002 | Journal of Alzheimer's Disease
Alpha-synuclein (alphaSN) has been implicated in Parkinson's Disease (PD) and alphaSN is a major component of Lewy bodies (LBs). T..
Duck hepatitis B virus replication in primary bile duct epithelial cells
J Lee, JG Culvenor, P Angus, R Smallwood, A Nicoll, S Locarnini
Journal article | 2001 | Journal of Virology
Primary cultures of intrahepatic bile duct epithelial (IBDE) cells isolated from duckling livers were successfully grown for studi..
Doctor of Philosophy
University of Melbourne
Bachelor of Science (honours)
The Australian National University