Mark Rizzacasa

Total Synthesis of Viridiofungins A and B

Liselle Atkin, Angus Robertson, Jonathan M White, Mark A Rizzacasa

Journal article  |  2021  |  ORGANIC LETTERS

The total synthesis of viridiofungins A (1) and B (2) via β-lactone 3 in 13 steps is reported. Key steps included an HF-mediated r..

Chemistry and biology of spiroacetals from myxobacteria

Michael Ricca, Mark A Rizzacasa

Journal article  |  2021  |  ORGANIC & BIOMOLECULAR CHEMISTRY

This review details the isolation, biosynthesis, biological activity and synthesis of spiroacetals from the myxobacterium Sorangiu..

2019 highlights of the structural revision of natural product via total synthesis

Zongjia Chen, Mark A Rizzacasa

Journal article  |  2020  |  FRONTIERS OF CHEMICAL SCIENCE AND ENGINEERING

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Total Synthesis of ( )-Trachyspic Acid 19-n-Butyl Ester

Alex A Rafaniello, Mark A Rizzacasa

Journal article  |  2020  |  ORGANIC LETTERS

The first total synthesis of the alkyl citrate trachyspic acid 19-n-butyl ester (1) is described. A formal [2 + 2]-cycloaddition o..

Frontispiece: The Nargenicin Family of Oxa‐Bridged Macrolide Antibiotics

Sacha J Pidot, Mark A Rizzacasa

Journal article  |  2020  |  Chemistry – A European Journal

The Nargenicin Family of Oxa-Bridged Macrolide Antibiotics

Sacha J Pidot, Mark A Rizzacasa

Journal article  |  2019  |  CHEMISTRY-A EUROPEAN JOURNAL

The nargenicin family of antibiotic macrolides comprise a group of bacterial natural products with a rare ether bridged cis-decali..

Total Synthesis and Stereochemical Reassignment of Citrafungin A

Zongjia Chen, Angus Robertson, Jonathan M White, Mark A Rizzacasa

Journal article  |  2019  |  ORGANIC LETTERS

The stereoselective 12-step total synthesis of the reassigned structure for citrafungin A (1a) via cyclobutene diester 10 is descr..

An effective cis-beta-octahedral Mn(iii) SALPN catalyst for the Mukaiyama-Isayama hydration of alpha,beta-unsaturated esters

Paul S Donnelly, Andrea J North, Natalia Caren Radjah, Michael Ricca, Angus Robertson, Jonathan M White, Mark A Rizzacasa

Journal article  |  2019  |  CHEMICAL COMMUNICATIONS

Two cis-β-MnIIISALPN catalysts were synthesised and tested in the Mukaiyama-Isayama hydration of α,β-unsaturated esters. The MnIII..

Biosynthesis and Ether-Bridge Formation in Nargenicin Macrolides

Sacha J Pidot, Marion Herisse, Liam Sharkey, Liselle Atkin, Jessica L Porter, Torsten Seemann, Benjamin P Howden, Mark A Rizzacasa, Timothy P Stinear

Journal article  |  2019  |  ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

The nargenicin family of antibiotics are macrolides containing a rare ether-bridged cis-decalin motif. Several of these compounds ..

Biosynthesis and Ether‐Bridge Formation in Nargenicin Macrolides

Sacha J Pidot, Marion Herisse, Liam Sharkey, Liselle Atkin, Jessica L Porter, Torsten Seemann, Benjamin P Howden, Mark A Rizzacasa, Timothy P Stinear

Journal article  |  2019  |  Angewandte Chemie

Abstract: The nargenicin family of antibiotics are macrolides containing a rare ether‐bridged cis‐decalin motif. Several of these ..