Christos Pantelis

Cognitive ability and metabolic physical health in first-episode psychosis.

Sarah Whitson, Brian O'Donoghue, Robert Hester, Lara Baldwin, Susy Harrigan, Shona Francey, Jessica Graham, Barnaby Nelson, Aswin Ratheesh, Mario Alvarez-Jimenez, Alex Fornito, Christos Pantelis, Hok Pan Yuen, Andrew Thompson, Melissa Kerr, Michael Berk, Stephen J Wood, Patrick McGorry, Kelly Allott

Journal article  |  2021  |  Schizophrenia Research Cognition

Cognitive impairments are a core feature of first-episode psychosis (FEP), arising before illness onset and antipsychotic exposure..

Increased peripheral inflammation in schizophrenia is associated with worse cognitive performance and related cortical thickness reductions

Hayley F North, Jason Bruggemann, Vanessa Cropley, Vaidy Swaminathan, Suresh Sundram, Rhoshel Lenroot, Avril M Pereira, Andrew Zalesky, Chad Bousman, Christos Pantelis, Thomas W Weickert, Cynthia Shannon Weickert

Journal article  |  2021  |  European Archives of Psychiatry and Clinical Neuroscience

While the biological substrates of brain and behavioural changes in persons with schizophrenia remain unclear, increasing evidence..

Symptom Remission and Brain Cortical Networks at First Clinical Presentation of Psychosis: The OPTiMiSE Study.

Paola Dazzan, Andrew J Lawrence, Antje ATS Reinders, Alice Egerton, Neeltje EM van Haren, Kate Merritt, Gareth J Barker, Rocio Perez-Iglesias, Kyra-Verena Sendt, Arsime Demjaha, Kie W Nam, Iris E Sommer, Christos Pantelis, W Wolfgang Fleischhacker, Inge Winter van Rossum, Silvana Galderisi, Armida Mucci, Richard Drake, Shon Lewis, Mark Weiser, et al.

Journal article  |  2021  |  Schizophrenia Bulletin

Individuals with psychoses have brain alterations, particularly in frontal and temporal cortices, that may be particularly promine..

Network Analysis of Symptom Comorbidity in Schizophrenia: Relationship to Illness Course and Brain White Matter Microstructure

Hua Ye, Andrew Zalesky, Jinglei Lv, Samantha M Loi, Suheyla Cetin-Karayumak, Yogesh Rathi, Ye Tian, Christos Pantelis, Maria A Di Biase

Journal article  |  2021  |  Schizophrenia Bulletin

INTRODUCTION: Recent network-based analyses suggest that schizophrenia symptoms are intricately connected and interdependent, such..

Association between age of cannabis initiation and gray matter covariance networks in recent onset psychosis

Nora Penzel, Linda A Antonucci, Linda T Betz, Rachele Sanfelici, Johanna Weiske, Oliver Pogarell, Paul Cumming, Boris B Quednow, Oliver Howes, Peter Falkai, Rachel Upthegrove, Alessandro Bertolino, Stefan Borgwardt, Paolo Brambilla, Rebekka Lencer, Eva Meisenzahl, Marlene Rosen, Theresa Haidl, Lana Kambeitz-Ilankovic, Stephan Ruhrmann, et al.

Journal article  |  2021  |  Neuropsychopharmacology

Cannabis use during adolescence is associated with an increased risk of developing psychosis. According to a current hypothesis, t..

Associations between cognition and white matter microstructure in first-episode antipsychotic-naïve patients with schizophrenia and healthy controls: A multivariate pattern analysis

Marie B Thomas, Jayachandra M Raghava, Christos Pantelis, Egill Rostrup, Mette Ø Nielsen, Maria H Jensen, Birte Y Glenthøj, René CW Mandl, Bjørn H Ebdrup, Birgitte Fagerlund

Journal article  |  2021  |  Cortex

A polygenic resilience score moderates the genetic risk for schizophrenia

Jonathan L Hess, Daniel S Tylee, Manuel Mattheisen, Anders D Borglum, Thomas D Als, Jakob Grove, Thomas Werge, Preben Bo Mortensen, Ole Mors, Merete Nordentoft, David M Hougaard, Jonas Byberg-Grauholm, Marie Baekvad-Hansen, Tiffany A Greenwood, Ming T Tsuang, David Curtis, Stacy Steinberg, Engilbert Sigurdsson, Hreinn Stefansson, Kari Stefansson, et al.

Journal article  |  2021  |  Molecular Psychiatry

Based on the discovery by the Resilience Project (Chen R. et al. Nat Biotechnol 34:531-538, 2016) of rare variants that confer res..

Large-Scale Evidence for an Association Between Peripheral Inflammation and White Matter Free Water in Schizophrenia and Healthy Individuals

Maria A Di Biase, Andrew Zalesky, Suheyla Cetin-Karayumak, Yogesh Rathi, Jinglei Lv, Danny Boerrigter, Hayley North, Paul Tooney, Christos Pantelis, Ofer Pasternak, Cynthia Shannon Weickert, Vanessa L Cropley

Journal article  |  2021  |  Schizophrenia Bulletin

INTRODUCTION: Clarifying the role of neuroinflammation in schizophrenia is subject to its detection in the living brain. Free-wate..

Differentiating the effect of antipsychotic medication and illness on brain volume reductions in first-episode psychosis: A Longitudinal, Randomised, Triple-blind, Placebo-controlled MRI Study

Sidhant Chopra, Alex Fornito, Shona M Francey, Brian O'Donoghue, Vanessa Cropley, Barnaby Nelson, Jessica Graham, Lara Baldwin, Steven Tahtalian, Hok Pan Yuen, Kelly Allott, Mario Alvarez-Jimenez, Susy Harrigan, Kristina Sabaroedin, Christos Pantelis, Stephen J Wood, Patrick McGorry

Journal article  |  2021  |  Neuropsychopharmacology

Changes in brain volume are a common finding in Magnetic Resonance Imaging (MRI) studies of people with psychosis and numerous lon..

Systematic Review: Quantitative Susceptibility Mapping (QSM) of Brain Iron Profile in Neurodegenerative Diseases

Parsa Ravanfar, Samantha M Loi, Warda T Syeda, Tamsyn E Van Rheenen, Ashley I Bush, Patricia Desmond, Vanessa L Cropley, Darius JR Lane, Carlos M Opazo, Bradford A Moffat, Dennis Velakoulis, Christos Pantelis

Journal article  |  2021  |  Frontiers in Neuroscience

Iron has been increasingly implicated in the pathology of neurodegenerative diseases. In the past decade, development of the new m..