Christine Wright

The effects of varying Mg2 ion concentrations on contractions to the cotransmitters ATP and noradrenaline in the rat vas deferens.

Amna C Mazeh, James A Angus, Christine E Wright

Journal article  |  2019  |  Autonomic Neuroscience

The vas deferens responds to a single electrical pulse with a biphasic contraction caused by cotransmitters ATP and noradrenaline...

Using high-resolution Twin-Ion Metabolite Extraction (HiTIME) mass spectrometry with stable isotope labelling to investigate the metabolism of valproic acid in vivo

Michael G Leeming, Noel Cranswick, Christine E Wright, James Ziogas, Terence J O'Brien, William A Donald, Richard AJ O'Hair

Journal article  |  2019  |  International Journal of Mass Spectrometry

Role of endothelin-1 clearance in the haemodynamic responses to endothelin-1 in the pulmonary and hindquarter vasculature of anaesthetised rats

James A Angus, Christine E Wright

Journal article  |  2019  |  European Journal of Pharmacology

Letter by Angus and Wright Regarding Article, "Pannexin-1 Channels as an Unexpected New Target of the Antihypertensive Drug Spironolactone"

James A Angus, Christine E Wright

Journal article  |  2018  |  Circulation Research

Distortion of K-B estimates of endothelin-1 ETA and ETB receptor antagonists in pulmonary arteries: Possible role of an endothelin-1 clearance mechanism

James A Angus, Richard JA Hughes, Christine E Wright

Journal article  |  2017  |  Pharmacology Research & Perspectives

Functional estimation of endothelin-1 receptor antagonism by bosentan, macitentan and ambrisentan in human pulmonary and radial arteries in vitro

James A Angus, Paul F Soeding, Richard JA Hughes, Christine E Wright

Journal article  |  2017  |  European Journal of Pharmacology

Novel technique to determine the pK(A) of clonidine at prejunctional alpha(2)-adrenoceptors in cardiac and vascular sympathetic transmission

James A Angus, Pravin Rajasekaran, Christine E Wright

Journal article  |  2017  |  European Journal of Pharmacology

Proteomics and antivenomics of Papuan black snake (Pseudechis papuanus) venom with analysis of its toxicological profile and the preclinical efficacy of Australian antivenoms

Davinia Pla, Benjamin W Bande, Ronelle E Welton, Owen K Paiva, Libia Sanz, Alvaro Segura, Christine E Wright, Juan J Calvete, Jose Maria Gutierrez, David J Williams

Journal article  |  2017  |  Journal of Proteomics

Evidence of a Cardiovascular Function for Microtubule-Associated Protein Tau

Ashenafi H Betrie, Scott Ayton, Ashley I Bush, James A Angus, Peng Lei, Christine E Wright

Journal article  |  2017  |  Journal of Alzheimer's Disease

Novel alpha(1)-adrenoceptor antagonism by the fluroquinolone antibiotic trovafloxacin

James A Angus, Christine E Wright

Journal article  |  2016  |  European Journal of Pharmacology

Vascular reactivity of rabbit isolated renal and femoral resistance arteries in renal wrap hypertension

Makhala M Khammy, James A Angus, Christine E Wright

Journal article  |  2016  |  European Journal of Pharmacology

Neutralization of the neuromuscular inhibition of venom and taipoxin from the taipan (Oxyuranus scutellatus) by F(ab ') 2 and whole IgG antivenoms

Maria Herrera, Rita de Cassia de O Collaco, Mauren Villalta, Alvaro Segura, Mariangela Vargas, Christine E Wright, Owen K Paiva, Teatulohi Matainaho, Simon D Jensen, Guillermo Leon, David J Williams, Lea Rodrigues-Simioni, Jose Maria Gutierrez

Journal article  |  2016  |  Toxicology Letters

ATP is not involved in alpha(1)-adrenoceptor-mediated vasoconstriction in resistance arteries

James A Angus, Christine E Wright

Journal article  |  2015  |  European Journal of Pharmacology

Comparative study of the toxic effects of Chrysaora quinquecirrha (Cnidaria: Scyphozoa) and Chironex fleckeri (Cnidaria: Cubozoa) venoms using cell-based assays

Dalia Ponce, Diane L Brinkman, Karen Luna-Ramirez, Christine E Wright, Juan Jose Dorantes-Aranda

Journal article  |  2015  |  Toxicon

Contrasting cardiovascular properties of the mu-opioid agonists morphine and methadone in the rat

Kenneth H Tung, James A Angus, Christine E Wright

Journal article  |  2015  |  European Journal of Pharmacology

High-Resolution Twin-Ion Metabolite Extraction (HiTIME) Mass Spectrometry: Nontargeted Detection of Unknown Drug Metabolites by Isotope Labeling, Liquid Chromatography Mass Spectrometry, and Automated High-Performance Computing

Michael G Leeming, Andrew P Isaac, Bernard J Pope, Noel Cranswick, Christine E Wright, James Ziogas, Richard AJ O'Hair, William A Donald

Journal article  |  2015  |  Analytical Chemistry

Pannexin-1 channels do not regulate alpha(1)-adrenoceptor-mediated vasoconstriction in resistance arteries

James A Angus, Ashenafi H Betrie, Christine E Wright

Journal article  |  2015  |  European Journal of Pharmacology

Synthesis of six mexiletine derivatives with isoindolines attached as potential antioxidants and their evaluation as cardioprotective agents

Bich Anh Chau, Grant Drummond, W Roy Jackson, Bevyn Jarrott, Alyson A Miller, Kamani R Subasinghe, Christina YR Tan, Paul J White, Christine E Wright, James Ziogas

Journal article  |  2015  |  MedChemComm

The role of voltage-operated and non-voltage-operated calcium channels in endothelin-induced vasoconstriction of rat cerebral arteries

Yohannes A Mamo, James A Angus, James Ziogas, Paul F Soeding, Christine E Wright

Journal article  |  2014  |  European Journal of Pharmacology

Vasoconstrictor Responses to Vasopressor Agents in Human Pulmonary and Radial Arteries An In Vitro Study

Dale A Currigan, Richard JA Hughes, Christine E Wright, James A Angus, Paul F Soeding

Journal article  |  2014  |  Anesthesiology

Preclinical efficacy of Australian antivenoms against the venom of the small-eyed snake, Micropechis ikaheka, from Papua New Guinea: An antivenomics and neutralization study

Davinia Pla, Owen K Paiva, Libia Sanz, Markus Beutler, Christine E Wright, Juan J Calvete, David J Williams, Jose Maria Gutierrez

Journal article  |  2014  |  Journal of Proteomics

Combined venom gland cDNA sequencing and venomics of the New Guinea small-eyed snake, Micropechis ikaheka

Owen Paiva, Davinia Pla, Christine E Wright, Markus Beutler, Libia Sanz, Jose Maria Gutierrez, David J Williams, Juan J Calvete

Journal article  |  2014  |  Journal of Proteomics

Membrane interactions and biological activity of antimicrobial peptides from Australian scorpion

Karen Luna-Ramirez, Marc-Antoine Sani, Jesus Silva-Sanchez, Juana Maria Jimenez-Vargas, Fernando Reyna-Flores, Kenneth D Winkel, Christine E Wright, Lourival D Possani, Frances Separovic

Journal article  |  2014  |  Biochimica et Biophysica Acta-Biomembranes

Efficacy of Australian red-back spider (Latrodectus hasselti) antivenom in the treatment of clinical envenomation by the cupboard spider Steatoda capensis (Theridiidae)

Bakhadir U Atakuziev, Christine E Wright, Andis Graudins, Graham M Nicholson, Kenneth D Winkel

Journal article  |  2014  |  Toxicon

Structure, Molecular Modeling, and Function of the Novel Potassium Channel Blocker Urotoxin Isolated from the of the Australian Scorpion Urodacus yaschenkoi

Karen Luna-Ramirez, Adam Bartok, Rita Restano-Cassulini, Veronica Quintero-Hernandez, Fredy IV Coronas, Janni Christensen, Christine E Wright, Gyorgy Panyi, Lourival D Possani

Journal article  |  2014  |  Molecular Pharmacology

Endothelin-1-Mediated Contraction Of Intrapulmonary Arteries And Airways In Rat Lung Slices

M FitzPatrick, CE Wright, JE Bourke

Conference Proceedings  |  2014  |  AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

Paul I Korner (1925-2012) OBITUARY

Roger Evans, Jaye Chin-Dusting, Geoff Head, Christine Wright, Jean-Luc Elghozi, Peter Friberg, Michael A Adams, Carol-Ann Courneya, Emilio Badoer, Bronwyn Kingwell

Journal article  |  2013  |  Clinical and Experimental Pharmacology and Physiology

Dual action molecules: Bioassays of combined novel antioxidants and angiotensin II receptor antagonists

Nitya V Jani, James Ziogas, James A Angus, Carl H Schiesser, Phoebe E Macdougall, Rebecca L Grange, Christine E Wright

Journal article  |  2012  |  European Journal of Pharmacology

Exogenous glutathione is essential in the testing of antioxidant capacity using radical-induced haemolysis

Nitya Jani, James Ziogas, James A Angus, Christine E Wright

Journal article  |  2012  |  Journal of Pharmacological and Toxicological Methods

In vivo techniques and analysis

JA Angus, CE Wright, K Sudhir, GJ Jennings

Book Chapter  |  2012

A pharmacological investigation of the venom extract of the Australian box jellyfish, Chironex fleckeri, in cardiac and vascular tissues

Richard JA Hughes, James A Angus, Kenneth D Winkel, Christine E Wright

Journal article  |  2012  |  Toxicology Letters

Analytical pharmacology and the elucidation of function

James A Angus, Paul I Korner, Christine E Wright

Journal article  |  2011  |  Trends in Pharmacological Sciences

The pharmacology of Malo maxima jellyfish venom extract in isolated cardiovascular tissues: A probable cause of the Irukandji syndrome in Western Australia

Ran Li, Christine E Wright, Kenneth D Winkel, Lisa-Ann Gershwin, James A Angus

Journal article  |  2011  |  Toxicology Letters

Levosimendan preserves the contractile responsiveness of hypoxic human myocardium via mitochondrial K-ATP channel and potential pERK 1/2 activation

Paul F Soeding, Peter J Crack, Christine E Wright, James A Angus, Colin F Royse

Journal article  |  2011  |  European Journal of Pharmacology

Novel paramagnetic AT(1) receptor antagonists

Nichole PH Tan, Michelle K Taylor, Steven E Bottle, Christine E Wright, James Ziogas, Jonathan M White, Carl H Schiesser, Nitya V Jani

Journal article  |  2011  |  Chemical Communications

A new approach to assessing the structural total peripheral resistance amplifier in renal (Page) hypertension in conscious rabbits

Paul I Korner, Christine E Wright, James A Angus

Journal article  |  2010  |  Journal of Hypertension

A review of local anesthetic cardiotoxicity and treatment with lipid emulsion.

Emma Bourne, Christine Wright, Colin Royse

Journal article  |  2010  |  Local and Regional Anesthesia

Cardiovascular collapse from accidental local anesthetic toxicity is a rare but catastrophic complication of regional anesthesia. ..

Vascular Effects of FGF-2 and VEGF-B in Rabbits with Bilateral Hind Limb Ischemia

Rafif Wafai, Elizabeth M Tudor, James A Angus, Christine E Wright

Journal article  |  2009  |  Journal of Vascular Research

Advantages of a selective beta-isofonn phosphoinositide 3-kinase antagonist, an anti-thrombotic agent devoid of other cardiovascular actions in the rat

Sharelle A Sturgeon, Catherine Jones, James A Angus, Christine E Wright

Journal article  |  2008  |  European Journal of Pharmacology

Inoprotection review - Reply

PF Soeding, CF Royse, CE Wright, AG Royse, JA Angus

Journal article  |  2008  |  Anaesthesia and Intensive Care

Synthesis and cannabinoid activity of 1-sub stituted-indole-3-oxadiazole derivatives: Novel agonists for the CB1 receptor

Gerard P Moloney, James A Angus, Alan D Robertson, Martin J Stoermer, Michael Robinson, Christine E Wright, Ken McRae, Arthur Christopoulos

Journal article  |  2008  |  European Journal of Medicinal Chemistry

Persistent depression of contractility and vasodilation with propofol but not with sevoflurane or desflurane in rabbits

Colin Forbes Royse, David FL Liew, Christine E Wright, Alistair G Royse, James A Angus

Journal article  |  2008  |  Anesthesiology

Adaptation of hindquarter vascular reactivity to femoral artery ligation and hypercholesterolemia in the rabbit

Rafif Wafai, James A Angus, Christine E Wright

Journal article  |  2008  |  Journal of Vascular Research

Synthesis and cannabinoid activity of a variety of 2,3-substituted 1-benzo[b]thiophen derivatives and 2,3-substituted benzofuran: Novel agonists for the CB(1) receptor

Gerard P Moloney, James A Angus, Alan D Robertson, Martin J Stoermer, Michael Robinson, Lucy Lay, Christine E Wright, Ken McRae, Arthur Christopoulos

Journal article  |  2008  |  Australian Journal of Chemistry

Inoprotection: the perioperative role of levosimendan

PF Soeding, CF Royse, CE Wright, AG Royse, JA Angus

Journal article  |  2007  |  Anaesthesia and Intensive Care

Tissue engineering of a vascularised myocardial patch

AN Morritt, SK Bortolotto, RJ Dilley, XL Han, AR Kompa, D McCombe, CE Wright, S Itescu, JA Angus, WA Morrison

Conference Proceedings  |  2007  |  TISSUE ENGINEERING

The cardiovascular effects of adrenaline, dobutamine and milrinone in rabbits using pressure-volume loops and guinea pig isolated atrial tissue

CF Royse, AG Royse, R Rohrlach, CE Wright, JA Angus

Journal article  |  2007  |  Anaesthesia and Intensive Care

Cardiac tissue engineering in an in vivo vascularized chamber

Andrew N Morritt, Susan K Bortolotto, Rodney J Dilley, XiaoLian Han, Andrew R Kompa, David McCombe, Christine E Wright, Silviu Itescu, James A Angus, Wayne A Morrison

Journal article  |  2007  |  Circulation

Thrombin overcomes the thrombosis defect associated with platelet GPVI/FcR gamma deficiency

Pierre Mangin, Cindy L Yap, Christelle Nonne, Sharelle A Sturgeon, Isaac Goncalves, Yuping Yuan, Simone M Schoenwaelder, Christine E Wright, Francois Lanza, Shaun P Jackson

Journal article  |  2006  |  Blood

Arterial antithrombotic effects of aspirin, heparin, enoxaparin and clopidogrel alone, or in combination, in the rat

Heather J Daykin, Sharelle A Sturgeon, Catherine Jones, Christine E Wright

Journal article  |  2006  |  Thrombosis Research

The biology of vascular endothelial growth factor-B (VEGF-B)

AD Nash, M Baca, C Wright, PD Scotney

Journal article  |  2006  |  Pulmonary Pharmacology and Therapeutics

Adaptation of the Folts and electrolytic methods of arterial thrombosis for the study of anti-thrombotic molecules in small animals.

Sharelle A Sturgeon, Catherine Jones, James A Angus, Christine E Wright

Journal article  |  2006  |  Journal of Pharmacological and Toxicological Methods

INTRODUCTION: Animal preparations of arterial thrombosis play a crucial role in the discovery and validation of novel drug targets..

Cardiovascular actions of the venom from the Irukandji (Carukia barnesi) jellyfish: Effects in human, rat and guinea-pig tissues in vitro and in pigs in vivo

KD Winkel, J Tibballs, P Molenaar, G Lambert, P Coles, M Ross-Smith, C Wiltshire, PJ Fenner, LA Gershwin, GM Hawdon, CE Wright, JA Angus

Journal article  |  2005  |  Clinical and Experimental Pharmacology and Physiology

PI 3-kinase p110 beta: a new target for antithrombotic therapy

SP Jackson, SM Schoenwaelder, I Goncalves, WS Nesbitt, CL Yap, CE Wright, V Kenche, KE Anderson, SM Dopheide, YP Yuan, SA Sturgeon, H Prabaharan, PE Thompson, GD Smith, PR Shepherd, N Daniele, S Kulkarni, B Abbott, D Saylik, C Jones, et al.

Journal article  |  2005  |  Nature Medicine

Synergistic and additive interactions of the cannabinoid agonist CP55,940 with mu opioid receptor and alpha(2)-adrenoceptor agonists in acute pain models in mice

SM Tham, JA Angus, EM Tudor, CE Wright

Journal article  |  2005  |  British Journal of Pharmacology

Synergy between intrathecal omega-conotoxin CVID and dexmedetomidine to attenuate mechanical hypersensitivity in the rat

DW Blake, DA Scott, JA Angus, CE Wright

Journal article  |  2005  |  European Journal of Pharmacology

Evidence that CB-1 and CB-2 cannabinoid receptors mediate antinociception in neuropathic pain in the rat

DA Scott, CE Wright, JA Angus

Journal article  |  2004  |  Pain

Endothelin and the sympathetic nervous system

JA ANGUS, CE WRIGHT

Book Chapter  |  2004

Central endogenous histamine modulates sympathetic outflow through H-3 receptors in the conscious rabbit

J Charles, JA Angus, CE Wright

Journal article  |  2003  |  British Journal of Pharmacology

Cardiovascular reflex responses after intrathecal omega-conotoxins or dexmedetomidine in the rabbit

DW Blake, CE Wright, DA Scott, JA Angus

Journal article  |  2003  |  Clinical and Experimental Pharmacology and Physiology

Effects of vascular endothelial growth factor (VEGF)(A) and VEGF(B) gene transfer on vascular reserve in a conscious rabbit hindlimb ischaemia model

CE Wright

Conference Proceedings  |  2002  |  Clinical and Experimental Pharmacology and Physiology

Actions of intrathecal omega-conotoxins CVID, GVIA, MVIIA, and morphine in acute and neuropathic pain in the rat

DA Scott, CE Wright, JA Angus

Journal article  |  2002  |  European Journal of Pharmacology

Should high-normal blood pressure be treated?

V Tikhonoff, E Casiglia, T Nawrot, JA Staessen

Journal article  |  2002  |  Journal of Hypertension

The interactive vascular resistance amplifier and non-interactive reviewers.

Christine E Wright, James A Angus, Paul I Korner

Journal article  |  2002  |  Journal of Hypertension

Acute effects of L- and T-type calcium channel antagonists on cardiovascular reflexes in conscious rabbits

MG Devlin, JA Angus, KM Wilson, CE Wright

Journal article  |  2002  |  Clinical and Experimental Pharmacology and Physiology

The interactive vascular resistance amplifier and non-interactive reviewers

CE Wright, JA Angus, PI Korner

Journal article  |  2002  |  Journal of Hypertension

Structural factors increase blood pressure through the interaction of resistance vessel geometry with neurohumoral and local factors: estimates in rabbits with renal cellophane-wrap hypertension with intact effectors and during neurohumoral blockade

CE Wright, JA Angus, PI Korner

Journal article  |  2002  |  Journal of Hypertension

Targeting voltage-gated Ca2 channels - Reply

JA Angus, CE Wright, Q Xi

Journal article  |  2001  |  The Lancet

Cardiovascular and autonomic effects of omega-conotoxins MVIIA and CVID in conscious rabbits and isolated tissue assays

CE Wright, AD Robertson, SL Whorlow, JA Angus

Journal article  |  2000  |  British Journal of Pharmacology

Targetting voltage-gated calcium channels in cardiovascular therapy

JA Angus, CE Wright, Q Xi

Journal article  |  2000  |  The Lancet

Techniques to measure pharmacodynamics in the intact vasculature

CE Wright, JA Angus

Journal article  |  2000  |  Journal of Pharmacological and Toxicological Methods

Techniques to study the pharmacodynamics of isolated large and small blood vessels

JA Angus, CE Wright

Journal article  |  2000  |  Journal of Pharmacological and Toxicological Methods

Pharmacological characterisation of cannabinoid CB1 receptors in the rat and mouse

L Lay, JA Angus, CE Wright

Journal article  |  2000  |  European Journal of Pharmacology

Role of NPYY1 receptors in cardiovascular control in the conscious rabbit

AP Serone, CE Wright, JA Angus

Journal article  |  2000  |  Journal of Cardiovascular Pharmacology

Structure and the resistance amplifier in hypertension: reply to the dissenters

PI Korner, JA Angus, CE Wright

Journal article  |  2000  |  Journal of Hypertension

Structure and the resistance amplifier in hypertension: Reply to the dissenters (multiple letters)

PI Korner, JA Angus, CE Wright

Journal article  |  2000  |  Journal of Hypertension

Protective and pathological roles of nitric oxide in endotoxin shock

CE Wright, DD Rees, S Moncada

Journal article  |  2000  |  CARDIOVASCULAR RESEARCH

Postural hypotension following N-type Ca2 channel blockade is amplified in experimental hypertension

CE Wright, AL Hawkes, JA Angus

Journal article  |  2000  |  Journal of Hypertension

Enhanced total peripheral vascular responsiveness in hypertension accords with the amplifier hypothesis

CE Wright, JA Angus

Journal article  |  1999  |  Journal of Hypertension

Heterogeneity of prejunctional NPY receptor-mediated inhibition of cardiac neurotransmission

AP Serone, CE Wright, JA Angus

Journal article  |  1999  |  British Journal of Pharmacology

Polypeptide omega-conotoxin GVIA as a basis for new analgesic and neuroprotective agents

RS Norton, PK Pallaghy, JB Baell, CE Wright, MJ Lew, JA Angus

Journal article  |  1999  |  Drug Development Research

Polypeptide ω‐conotoxin GVIA as a basis for new analgesic and neuroprotective agents

Raymond S Norton, Paul K Pallaghy, Jonathan B Baell, Christine E Wright, Michael J Lew, James A Angus

Journal article  |  1999  |  Drug Development Research

Endogenous angiotensin II and bradykinin delay and attenuate the hypotension after N-type calcium channel blockade in conscious rabbits

SL Whorlow, JA Angus, CE Wright

Journal article  |  1998  |  Journal of Cardiovascular Pharmacology

Exogenous NPY modulation of cardiac autonomic reflexes and its pressor effect in the conscious rabbit

AP Serone, JA Angus, CE Wright

Journal article  |  1998  |  British Journal of Pharmacology

CB1 agonists and antagonist display tissue and species differences in rat and mouse

L Lay, GP Moloney, AD Robertson, CE Wright, JA Angus

Journal article  |  1998  |  NAUNYN-SCHMIEDEBERGS ARCHIVES OF PHARMACOLOGY

Neuropeptide Y fails to modulate cardiac autonomie transmission in the rabbit

AP Serone, JA Angus, CE Wright

Journal article  |  1997  |  Proceedings of the Western Pharmacology Society

Neuropeptide Y: A species-specific modulator of cardiac autonomie transmission

AP Serone, JA Angus, CE Wright

Journal article  |  1997  |  Proceedings of the Western Pharmacology Society

The role of neuropeptide y in cardiovascular function

JA Angus, MJ Lew, R Murphy, AP Serone, CE Wright

Journal article  |  1997  |  Proceedings of the Western Pharmacology Society

Prolonged cardiovascular effects of the N-type Ca2 channel antagonist omega-conotoxin GVIA in conscious rabbits

CE Wright, JA Angus

Journal article  |  1997  |  Journal of Cardiovascular Pharmacology

Structure-function relationships of omega-conotoxin GVIA - Synthesis, structure, calcium channel binding, and functional assay of alanine-substituted analogues

MJ Lew, JP Flinn, PK Pallaghy, R Murphy, SL Whorlow, CE Wright, RS Norton, JA Angus

Journal article  |  1997  |  Journal of Biological Chemistry

Differential effects of omega-conotoxin GVIA on cholinergic and noncholinergic secretomotor neurones in the guinea-pig small intestine

MA Vremec, JC Bornstein, CE Wright, A Humphrey

Journal article  |  1997  |  British Journal of Pharmacology

Distribution of N-type Ca2 channel binding sites in rabbit brain following central administration of omega-conotoxin GVIA

SL Whorlow, RE Loiacono, JA Angus, CE Wright

Journal article  |  1996  |  European Journal of Pharmacology

Effects of N-, P- and Q-type neuronal calcium channel antagonists on mammalian peripheral neurotransmission

CE Wright, JA Angus

Journal article  |  1996  |  British Journal of Pharmacology

Baroreffex resetting but no vascular tolerance in response to transdermal glyceryl trinitrate in conscious rabbits

AP Serone, JA Angus, CE Wright

Journal article  |  1996  |  British Journal of Pharmacology

Selectivity of omega-conotoxin GVIA for N-type calcium channels in rat isolated small mesenteric arteries

SL Whorlow, JA Angus, CE Wright

Journal article  |  1996  |  Clinical and Experimental Pharmacology and Physiology

Synthesis and biological characterization of a series of analogues of omega-conotoxin GVIA.

JP Flinn, R Murphy, JH Boublik, MJ Lew, CE Wright, JA Angus

Journal article  |  1995  |  Journal of Peptide Science

The 27-residue polypeptide omega-conotoxin GVIA (omega-CgTx), from the venom of the cone shell Conus geographus, blocks N-type neu..

OMEGA-CONOTOXIN GVIA AND PRAZOSIN, BUT NOT FELODIPINE, CAUSE POSTURAL HYPOTENSION IN RABBITS

AL HAWKES, JA ANGUS, CE WRIGHT

Journal article  |  1995  |  Clinical and Experimental Pharmacology and Physiology

omega-Conotoxin GVIA and prazosin, but not felodipine, cause postural hypotension in rabbits.

AL Hawkes, JA Angus, CE Wright

Journal article  |  1995  |  Clin Exp Pharmacol Physiol

1. The aim was to compare the effect of N-type calcium channel blockade by omega-conotoxin GVIA (omega-CTX) with alpha 1-adrenocep..

HEMODYNAMIC AND AUTONOMIC REFLEX EFFECTS OF CHRONIC N-TYPE CA2 CHANNEL BLOCKADE WITH OMEGA-CONOTOXIN GVIA IN CONSCIOUS NORMOTENSIVE AND HYPERTENSIVE RABBITS

CE WRIGHT, JA ANGUS

Journal article  |  1995  |  Journal of Cardiovascular Pharmacology

ω‐CONOTOXIN GVIA AND PRAZOSIN, BUT NOT FELODIPINE, CAUSE POSTURAL HYPOTENSION IN RABBITS

AL Hawkes, JA Angus, CE Wright

Journal article  |  1995  |  Clinical and Experimental Pharmacology and Physiology

THE EFFECTS OF CENTRAL ADMINISTRATION OF OMEGA-CONOTOXIN GVIA ON CARDIOVASCULAR PARAMETERS AND AUTONOMIC REFLEXES IN CONSCIOUS RABBITS

SL WHORLOW, JA ANGUS, CE WRIGHT

Journal article  |  1994  |  Clinical and Experimental Pharmacology and Physiology

EFFECT OF CHRONIC N-TYPE CALCIUM-CHANNEL BLOCKADE ON HEMODYNAMICS AND AUTONOMIC REFLEXES IN CONSCIOUS NORMOTENSIVE AND HYPERTENSIVE RABBITS

CE WRIGHT, JA ANGUS

Journal article  |  1993  |  CIRCULATION

RELEASE OF ENDOTHELIUM-DERIVED RELAXING FACTOR FROM RESISTANCE ARTERIES IN HYPERTENSION

JA ANGUS, AC DYKE, GL JENNINGS, PI KORNER, K SUDHIR, JE WARD, CE WRIGHT

Journal article  |  1992  |  Kidney International, Supplement

THE ROLES OF NITRIC-OXIDE IN ENDOTOXIN-SHOCK

CE WRIGHT, DD REES, S MONCADA

Conference Proceedings  |  1992  |  BIOLOGY OF NITRIC OXIDE 1 : PHYSIOLOGICAL AND CLINICAL ASPECTS

PROTECTIVE AND PATHOLOGICAL ROLES OF NITRIC-OXIDE IN ENDOTOXIN-SHOCK

CE WRIGHT, DD REES, S MONCADA

Journal article  |  1992  |  Cardiovascular Research

DIFFERENCES IN REGIONAL VASCULAR SENSITIVITY TO ENDOTHELIN-1 BETWEEN SPONTANEOUSLY HYPERTENSIVE AND NORMOTENSIVE WISTAR-KYOTO RATS

CE WRIGHT, JR FOZARD

Journal article  |  1990  |  British Journal of Pharmacology

CORONARY CIRCULATION AND 5-HYDROXYTRYPTAMINE

JA ANGUS, A BROUGHTON, TM COCKS, CE WRIGHT

Conference Proceedings  |  1990  |  CARDIOVASCULAR PHARMACOLOGY OF 5-HYDROXYTRYPTAMINE

5-carboxamidotryptamine elicits 5-HT2 and 5-HT3 receptor-mediated cardiovascular responses in the conscious rabbit: evidence for 5-HT release from platelets.

CE Wright, JA Angus

Journal article  |  1989  |  J Cardiovasc Pharmacol

The selective "5-HT1-like" receptor agonist 5-carboxamidotryptamine (5-CT, 0.2-1.6 micrograms/kg bolus i.v.), serotonin (5-HT, 3-1..

5-CARBOXAMIDOTRYPTAMINE ELICITS 5-HT2 AND 5-HT3 RECEPTOR-MEDIATED CARDIOVASCULAR-RESPONSES IN THE CONSCIOUS RABBIT - EVIDENCE FOR 5-HT RELEASE FROM PLATELETS

CE WRIGHT, JA ANGUS

Journal article  |  1989  |  Journal of Cardiovascular Pharmacology

REGIONAL VASODILATION IS A PROMINENT FEATURE OF THE HEMODYNAMIC-RESPONSE TO ENDOTHELIN IN ANESTHETIZED, SPONTANEOUSLY HYPERTENSIVE RATS

CE WRIGHT, JR FOZARD

Journal article  |  1988  |  European Journal of Pharmacology

DIVERSE VASCULAR-RESPONSES TO SEROTONIN IN THE CONSCIOUS RABBIT - EFFECTS OF SEROTONIN ANTAGONISTS ON RENAL-ARTERY SPASM

CE WRIGHT, JA ANGUS

Journal article  |  1987  |  Journal of Cardiovascular Pharmacology

VASCULAR AMPLIFIER PROPERTIES IN RENOVASCULAR HYPERTENSION IN CONSCIOUS RABBITS - HINDQUARTER RESPONSES TO CONSTRICTOR AND DILATOR STIMULI

CE WRIGHT, JA ANGUS, PI KORNER

Journal article  |  1987  |  Hypertension

EFFECTS OF HYPERTENSION AND HYPERCHOLESTEROLEMIA ON VASODILATION IN THE RABBIT

CE WRIGHT, JA ANGUS

Journal article  |  1986  |  Hypertension

HYPERTENSION ALTERS SLOPE AND RANGE BUT NOT SENSITIVITY TO VASOCONSTRICTOR AND VASODILATOR AGENTS IN THE RABBIT HINDQUARTER

CE WRIGHT, JA ANGUS, PI KORNER

Journal article  |  1986  |  Clinical and Experimental Pharmacology and Physiology

ENDOTHELIUM-DEPENDENT RELAXATION IS UNALTERED BY HYPERTENSION, CHOLESTEROL OR INTIMAL THICKENING

JA ANGUS, CE WRIGHT, TM COCKS, K SATOH, G CAMPBELL

Journal article  |  1986  |  Clinical and Experimental Pharmacology and Physiology

Haemodynamic response to ketanserin in rabbits with Page hypertension: comparison with prazosin.

CE Wright, JA Angus

Journal article  |  1983  |  Journal of Hypertension

The role of alpha 1-adrenoceptors in the hypotensive response to ketanserin was studied in conscious normotensive (sham-operated) ..

HYPOTENSIVE RESPONSE TO KETANSERIN IN CONSCIOUS RABBITS - ROLE OF ALPHA-ADRENOCEPTORS

CE WRIGHT, JA ANGUS, GP JACKMAN

Journal article  |  1983  |  CLINICAL AND EXPERIMENTAL PHARMACOLOGY AND PHYSIOLOGY