Christine Wright

Cannabidiol selectively inhibits the contraction of rat small resistance arteries: Possible role for CGRP and voltage-gated calcium channels

Amna C Mazeh, James A Angus, Christine E Wright

Journal article  |  2021  |  European Journal of Pharmacology

The pharmacology of cannabidiol, the non-psychoactive major component of Cannabis sativa, is of growing interest as it becomes mor..

The beta(2)-adrenoceptor agonist bronchodilators terbutaline and orciprenaline are also weak alpha(1)-adrenoceptor antagonists

Makhala M Khammy, Cindy Kha Han Truong, Christine E Wright, James A Angus

Journal article  |  2020  |  European Journal of Pharmacology

Recently, the β2-adrenoceptor agonist terbutaline was shown to have α1-adrenolytic activity in mouse isolated pulmonary arteries i..

Estimation of the vascular resistance amplifier in the renal vascular bed in conscious hypertensive rabbits: comparison with the total peripheral vasculature

Makhala M Khammy, James A Angus, Christine E Wright

Journal article  |  2020  |  Heliyon

The effects of varying Mg2 ion concentrations on contractions to the cotransmitters ATP and noradrenaline in the rat vas deferens

Amna C Mazeh, James A Angus, Christine E Wright

Journal article  |  2019  |  Autonomic Neuroscience

The vas deferens responds to a single electrical pulse with a biphasic contraction caused by cotransmitters ATP and noradrenaline...

Using high-resolution Twin-Ion Metabolite Extraction (HiTIME) mass spectrometry with stable isotope labelling to investigate the metabolism of valproic acid in vivo

Michael G Leeming, Noel Cranswick, Christine E Wright, James Ziogas, Terence J O'Brien, William A Donald, Richard AJ O'Hair

Journal article  |  2019  |  International Journal of Mass Spectrometry

Role of endothelin-1 clearance in the haemodynamic responses to endothelin-1 in the pulmonary and hindquarter vasculature of anaesthetised rats

James A Angus, Christine E Wright

Journal article  |  2019  |  European Journal of Pharmacology

Letter by Angus and Wright Regarding Article, "Pannexin-1 Channels as an Unexpected New Target of the Antihypertensive Drug Spironolactone"

James A Angus, Christine E Wright

Journal article  |  2018  |  Circulation Research

Distortion of K-B estimates of endothelin-1 ETA and ETB receptor antagonists in pulmonary arteries: Possible role of an endothelin-1 clearance mechanism

James A Angus, Richard JA Hughes, Christine E Wright

Journal article  |  2017  |  PHARMACOLOGY RESEARCH & PERSPECTIVES

Functional estimation of endothelin-1 receptor antagonism by bosentan, macitentan and ambrisentan in human pulmonary and radial arteries in vitro

James A Angus, Paul F Soeding, Richard JA Hughes, Christine E Wright

Journal article  |  2017  |  European Journal of Pharmacology

Novel technique to determine the pK(A) of clonidine at prejunctional alpha(2)-adrenoceptors in cardiac and vascular sympathetic transmission

James A Angus, Pravin Rajasekaran, Christine E Wright

Journal article  |  2017  |  European Journal of Pharmacology