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A/Prof

Barbara Coulson

Honorary
Microbiology And Immunology
science & technology
rotavirus
life sciences & biomedicine
humans
animals
virology
rotavirus infections
antibodies, monoclonal
antigens, viral
Barbara Coulson's Profile Picture
A/Prof

Barbara Coulson

 
Division
Medicine, Dentistry And Health Sciences
 
Primary Interest
Rotavirus
Barbara Coulson's Profile Picture
A/Prof

Barbara Coulson

 
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Barbara's  Short Profile
 

Find out more about Barbara Coulson's experience

Barbara Coulson's highlights

Projects

Displaying the 10 most recent projects by Barbara Coulson.

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UNDERSTANDING HOW VIRUS INFECTION ACCELERATES TYPE 1 DIABETES DEVELOPMENT

We linked rotavirus infection in children at-risk of type 1 diabetes with faster diabetes development. A heightened response to the virus is..

2016 - 2018
Completed
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NEW INSIGHT INTO GLYCAN REQUIREMENTS FOR ROTAVIRUS-CELL ATTACHMENT AND ENTRY

Rotavirus causes significant infection and loss of life in children, particularly in underdeveloped countries. This project will investigate..

2015 - 2018
Completed
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Rotavirus infection of type 1 interferon receptor knockout NOD mice

Rotavirus infection is the main cause of severe diarrhoea in children, and has been implicated in accelerated progression of genetically at-..

2013 - 2014
Completed
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Elucidating the pathogenic role of rotavirus infection in type 1 diabetes development

Rotavirus infection is the main cause of severe diarrhoea in children, and has been implicated in accelerated progression of genetically at-..

2013 - 2015
Completed
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Host responses to limit rotavirus infection and their evasion by rotavirus

Rotavirus is the main cause of severe diarrhoea in children worldwide. In this project, we aim to understand the nature of the first-line im..

2012 - 2014
Completed
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Rotavirus modulation of type 1 diabetes

2011 - 2012
Completed
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GLYCAN SPECIFICITY AND DEPENDENCE IN ROTAVIRUS HOST CELL INVASION

Rotavirus is a global pathogen that causes acute gastroenteritis resulting in dehydration and high levels of infant mortality. Annually, inf..

2010 - 2012
Completed
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STRUCTURE-BASED DISCOVERY OF ANTI-ROTAVIRAL AGENTS

Rotavirus causes, particularly in children under 5 years of age, significant loss of life worldwide. Over 600,000 children under 5 years of ..

2010 - 2012
Completed
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RESEARCH FELLOWSHIP - ASSOC PROF BARBARA COULSON

I am a virologist carrying out research to determine the mechanisms underlying rotavirus cellular tropism and the pathogenesis of rotavirus ..

2010 - 2015
Completed
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How does infection with rotavirus alter the rate at which mice show diabetes?

Rotavirus is the main cause of severe diarrhoea in children, and may contribute to progression to type 1 diabetes. We have now shown that ro..

2008 - 2010
Completed

16

Projects

Project Types

12

Research Grant

3

Research Contracts

1

Internal Research Grant

Scholarly Works

Displaying the 10 most recent scholarly works by Barbara Coulson.

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Global Review of the Age Distribution of Rotavirus Disease in Children Aged <5 Years Before the Introduction of Rotavirus Vaccination.

Mateusz Hasso-Agopsowicz, Chandresh Nanji Ladva, Benjamin Lopman, Colin Sanderson, Adam L Cohen, Jacqueline E Tate, Ximena Riveros, Ana Maria Henao-Restrepo, Andrew Clark, undefined Global Rotavirus Surveillance Network and Rotavirus Age Study Collaborators

Journal article  |  2019  |  Clinical Infectious Diseases

We sought datasets with granular age distributions of rotavirus-positive disease presentations among children <5 years of age, bef..

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Specificity and affinity of neuraminic acid exhibited by canine rotavirus strain K9 carbohydrate-binding domain (VP8*)

Rahul Mishra, Xing Yu, Chandan Kishor, Gavan Holloway, Kam Lau, Mark von Itzstein, Barbara S Coulson, Helen Blanchard

Journal article  |  2018  |  Journal of Molecular Recognition

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MHC class I expression in intestinal cells is reduced by rotavirus infection and increased in bystander cells lacking rotavirus antigen

Gavan Holloway, Fiona E Fleming, Barbara S Coulson

Journal article  |  2018  |  SCIENTIFIC REPORTS

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Rotavirus acceleration of type 1 diabetes in non-obese diabetic mice depends on type I interferon signalling

Jessica A Pane, Fiona E Fleming, Kate L Graham, Helen E Thomas, Thomas WH Kay, Barbara S Coulson

Journal article  |  2016  |  Scientific Reports

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Expanding diversity of glycan receptor usage by rotaviruses

Barbara S Coulson

Journal article  |  2015  |  Current Opinion in Virology

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Rotavirus NSP6 localizes to mitochondria via a predicted N-terminal alpha-helix

Gavan Holloway, Rebecca I Johnson, Yilin Kang, Vi T Dang, Diana Stojanovski, Barbara S Coulson

Journal article  |  2015  |  Journal of General Virology

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Substantial Receptor-induced Structural Rearrangement of Rotavirus VP8*: Potential Implications for Cross-Species Infection

Xing Yu, Rahul Mishra, Gavan Holloway, Mark von Itzstein, Barbara S Coulson, Helen Blanchard

Journal article  |  2015  |  ChemBioChem

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Innate immune responses to rotavirus infection in macrophages depend on MAVS but involve neither the NLRP3 inflammasome nor JNK and p38 signaling pathways

Izabel JM Di Fiore, Gavan Holloway, Barbara S Coulson

Journal article  |  2015  |  Virus Research

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Inside Cover: Substantial Receptor-induced Structural Rearrangement of Rotavirus VP8*: Potential Implications for Cross-Species Infection (ChemBioChem 15/2015)

Xing Yu, Rahul Mishra, Gavan Holloway, Mark von Itzstein, Barbara S Coulson, Helen Blanchard

Journal article  |  2015  |  ChemBioChem: a European journal of chemical biology

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NSP1 of human rotaviruses commonly inhibits NF-kappa B signalling by inducing beta-TrCP degradation

Izabel JM Di Fiore, Jessica A Pane, Gavan Holloway, Barbara S Coulson

Journal article  |  2015  |  JOURNAL OF GENERAL VIROLOGY

102

Scholarly Works

Keyword Analysis

Medical Microbiology
Clinical Health (organs, Diseases and Abnormal Conditions)
Clinical (organs, Diseases and Abnormal Conditions)
Microbiology
Immunology
Expanding Knowledge
Zoology

Credentials

Positions

Honorary

Microbiology And Immunology

Member Of The Editorial Board

The Journal of Virology Editorial Board

Associate Editor

BioMedCentral Microbiology

Editorial Board Member

Editorial Board of BioMedCentral Microbiology

Education

Doctor of Philosophy

University of Melbourne

Bachelor of Science (honours)

University of Melbourne

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