Barbara Coulson

Global Review of the Age Distribution of Rotavirus Disease in Children Aged <5 Years Before the Introduction of Rotavirus Vaccination.

Mateusz Hasso-Agopsowicz, Chandresh Nanji Ladva, Benjamin Lopman, Colin Sanderson, Adam L Cohen, Jacqueline E Tate, Ximena Riveros, Ana Maria Henao-Restrepo, Andrew Clark, undefined Global Rotavirus Surveillance Network and Rotavirus Age Study Collaborators

Journal article  |  2019  |  Clinical Infectious Diseases

We sought datasets with granular age distributions of rotavirus-positive disease presentations among children <5 years of age, bef..

Specificity and affinity of neuraminic acid exhibited by canine rotavirus strain K9 carbohydrate-binding domain (VP8*)

Rahul Mishra, Xing Yu, Chandan Kishor, Gavan Holloway, Kam Lau, Mark von Itzstein, Barbara S Coulson, Helen Blanchard

Journal article  |  2018  |  Journal of Molecular Recognition

The outer capsid spike protein VP4 of rotaviruses is a major determinant of infectivity and serotype specificity. Proteolytic clea..

MHC class I expression in intestinal cells is reduced by rotavirus infection and increased in bystander cells lacking rotavirus antigen

Gavan Holloway, Fiona E Fleming, Barbara S Coulson

Journal article  |  2018  |  SCIENTIFIC REPORTS

Detection of viral infection by host cells leads to secretion of type I interferon, which induces antiviral gene expression. The c..

Rotavirus acceleration of type 1 diabetes in non-obese diabetic mice depends on type I interferon signalling

Jessica A Pane, Fiona E Fleming, Kate L Graham, Helen E Thomas, Thomas WH Kay, Barbara S Coulson

Journal article  |  2016  |  Scientific Reports

Rotavirus infection is associated with childhood progression to type 1 diabetes. Infection by monkey rotavirus RRV accelerates dia..

Expanding diversity of glycan receptor usage by rotaviruses

Barbara S Coulson

Journal article  |  2015  |  Current Opinion in Virology

Rotaviruses are major etiologic agents of severe gastroenteritis in human and animals, infecting the mature intestinal epithelium...

Rotavirus NSP6 localizes to mitochondria via a predicted N-terminal alpha-helix

Gavan Holloway, Rebecca I Johnson, Yilin Kang, Vi T Dang, Diana Stojanovski, Barbara S Coulson

Journal article  |  2015  |  Journal of General Virology

Specific roles have been ascribed to each of the 12 known rotavirus proteins apart from the non-structural protein 6 (NSP6). Howev..

Substantial Receptor-induced Structural Rearrangement of Rotavirus VP8*: Potential Implications for Cross-Species Infection

Xing Yu, Rahul Mishra, Gavan Holloway, Mark von Itzstein, Barbara S Coulson, Helen Blanchard

Journal article  |  2015  |  ChemBioChem

Rotavirus-cell binding is the essential first step in rotavirus infection. This binding is a major determinant of rotavirus tropis..

Innate immune responses to rotavirus infection in macrophages depend on MAVS but involve neither the NLRP3 inflammasome nor JNK and p38 signaling pathways

Izabel JM Di Fiore, Gavan Holloway, Barbara S Coulson

Journal article  |  2015  |  Virus Research

Rotavirus infection is a major cause of life-threatening infantile gastroenteritis. The innate immune system provides an immediate..

Inside Cover: Substantial Receptor-induced Structural Rearrangement of Rotavirus VP8*: Potential Implications for Cross-Species Infection (ChemBioChem 15/2015)

Xing Yu, Rahul Mishra, Gavan Holloway, Mark von Itzstein, Barbara S Coulson, Helen Blanchard

Journal article  |  2015  |  ChemBioChem: a European journal of chemical biology

NSP1 of human rotaviruses commonly inhibits NF-kappa B signalling by inducing beta-TrCP degradation

Izabel JM Di Fiore, Jessica A Pane, Gavan Holloway, Barbara S Coulson

Journal article  |  2015  |  JOURNAL OF GENERAL VIROLOGY

Rotavirus is a leading cause of severe gastroenteritis in infants worldwide. Rotavirus nonstructural protein 1 (NSP1) is a virulen..