Maree Faux

Genes regulating membrane-associated E-cadherin and proliferation in adenomatous polyposis coli mutant colon cancer cells: High content siRNA screen

Lauren E King, Hui-Hua Zhang, Cathryn M Gould, Daniel W Thomas, Lachlan W Whitehead, Kaylene J Simpson, Antony W Burgess, Maree C Faux

Journal article  |  2020  |  PLoS One

Truncating mutations in the tumour suppressor gene APC occur frequently in colorectal cancers and result in the deregulation of Wn..

MLKL trafficking and accumulation at the plasma membrane control the kinetics and threshold for necroptosis

Andre L Samson, Ying Zhang, Niall D Geoghegan, Xavier J Gavin, Katherine A Davies, Michael J Mlodzianoski, Lachlan W Whitehead, Daniel Frank, Sarah E Garnish, Cheree Fitzgibbon, Anne Hempel, Samuel N Young, Annette V Jacobsen, Wayne Cawthorne, Emma J Petrie, Maree C Faux, Kristy Shield-Artin, Najoua Lalaoui, Joanne M Hildebrand, John Silke, et al.

Journal article  |  2020  |  Nature Communications

Mixed lineage kinase domain-like (MLKL) is the terminal protein in the pro-inflammatory necroptotic cell death program. RIPK3-medi..

Imbalance of the renin-angiotensin system may contribute to inflammation and fibrosis in IBD: a novel therapeutic target?

Mayur Garg, Simon G Royce, Chris Tikellis, Claire Shallue, Duygu Batu, Elena Velkoska, Louise M Burrell, Sheila K Patel, Lauren Beswick, Anvesh Jackson, Kaushali Britto, Matthew Lukies, Pavel Sluka, Hady Wardan, Yumiko Hirokawa, Chin Wee Tan, Maree Faux, Antony W Burgess, Patrick Hosking, Shaun Monagle, et al.

Journal article  |  2020  |  Gut

OBJECTIVE: We evaluated the influence of the renin-angiotensin system (RAS) on intestinal inflammation and fibrosis. DESIGN: Cultu..

Differential RNA-seq analysis comparing APC-defective and APC-restored SW480 colorectal cancer cells

Lauren E King, Christopher G Love, Oliver M Sieber, Maree C Faux, Antony W Burgess

Journal article  |  2016  |  Genomics Data

Partial inhibition of gp130-Jak-Stat3 signaling prevents Wnt-beta-catenin-mediated intestinal tumor growth and regeneration

Toby J Phesse, Michael Buchert, Emma Stuart, Dustin J Flanagan, Maree Faux, Shoukat Afshar-Sterle, Francesca Walker, Hui-Hua Zhang, Cameron J Nowell, Robert Jorissen, Chin Wee Tan, Yumiko Hirokawa, Moritz F Eissmann, Ashleigh R Poh, Jordane Malaterre, Helen B Pearson, David G Kirsch, Paolo Provero, Valeria Poli, Robert G Ramsay, et al.

Journal article  |  2014  |  Science Signaling

Immunopurification of adenomatous polyposis coli (APC) proteins.

Kerryn L Elliott, Bruno Catimel, Nicole L Church, Janine L Coates, Antony W Burgess, Meredith J Layton, Maree C Faux

Journal article  |  2013  |  BMC Research Notes

BACKGROUND: The adenomatous polyposis coli (APC) tumour suppressor gene encodes a 2843 residue (310 kDa) protein. APC is a multifu..

The tumor suppressor Apc controls planar cell polarities central to gut homeostasis

Julien Bellis, Isabelle Duluc, Beatrice Romagnolo, Christine Perret, Maree C Faux, Denis Dujardin, Caroline Formstone, Sally Lightowler, Robert G Ramsay, Jean-Noel Freund, Jan R De Mey

Journal article  |  2012  |  Journal of Cell Biology

Identification of a Wnt-induced protein complex by affinity proteomics using an antibody that recognizes a sub-population of beta-catenin

Meredith J Layton, Maree C Faux, Nicole L Church, Bruno Catimel, Nadia J Kershaw, Eugene A Kapp, Cameron Nowell, Janine L Coates, Antony W Burgess, Richard J Simpson

Journal article  |  2012  |  Biochimica et Biophysica Acta-Proteins and Proteomics

Restoration of full-length APC protein in SW480 colon cancer cells induces exosome-mediated secretion of DKK-4

Justin WE Lim, Rommel A Mathias, Eugene A Kapp, Meredith J Layton, Maree C Faux, Antony W Burgess, Hong Ji, Richard J Simpson

Journal article  |  2012  |  Electrophoresis

Solubilisation of the armadillo-repeat protein beta-catenin using a zwitterionic detergent allows resolution of phosphorylated forms by 2DE

Meredith J Layton, Nicole L Church, Maree C Faux, Hong Ji, Robert JA Goode, Eugene A Kapp, Antony W Burgess, Richard J Simpson

Journal article  |  2012  |  Electrophoresis