Susan Nilsson

Smad4 promotes diabetic nephropathy by modulating glycolysis and OXPHOS

Jinhua Li, Yu Bo Yang Sun, Weiyi Chen, Jinjin Fan, Songhui Li, Xinli Qu, Qikang Chen, Riling Chen, Dajian Zhu, Jinfeng Zhang, Zhuguo Wu, Honggang Chi, Simon Crawford, Viola Oorschot, Victor G Puelles, Peter G Kerr, Yi Ren, Susan K Nilsson, Mark Christian, Huanwen Tang, et al.

Journal article  |  2020  |  EMBO reports

Diabetic nephropathy (DN) is the leading cause of end-stage kidney disease. TGF-β1/Smad3 signalling plays a major pathological rol..

Osteopontin is An Important Regulative Component of the Fetal Bone Marrow Hematopoietic Stem Cell Niche

Huimin Cao, Benjamin Cao, Chad K Heazlewood, Melanie Domingues, Xuan Sun, Emmanuel Debele, Narelle E McGregor, Natalie A Sims, Shen Y Heazlewood, Susan K Nilsson

Journal article  |  2019  |  Cells

Combined Blockade of Smad3 and JNK Pathways Ameliorates Progressive Fibrosis in Folic Acid Nephropathy

M Jiang, J Fan, X Qu, S Li, SK Nilsson, YBY Sun, Y Chen, D Yu, D Liu, BC Liu, M Tang, W Chen, Y Ren, DJ Nikolic-Paterson, X Jiang, J Li, X Yu

Journal article  |  2019  |  Frontiers in Pharmacology

Mouse Hematopoietic Stem Cell Modification and Labelling by Transduction and Tracking Posttransplantation.

Benjamin Cao, Songhui Li, Claire Pritchard, Brenda Williams, Susan K Nilsson

Book Chapter  |  2019  |  Methods in Molecular Biology

The tracking of the hematopoietic potential of genetically manipulated fluorescent hematopoietic stem cells (HSC) in the bone marr..

Corrigendum to: Validating Eaton's Hypothesis: Cubane as a Benzene Bioisostere (Angewandte Chemie International Edition, (2016), 55, 11, (3580-3585), 10.1002/anie.201510675)

BA Chalmers, H Xing, S Houston, C Clark, S Ghassabian, A Kuo, B Cao, A Reitsma, CEP Murray, JE Stok, GM Boyle, CJ Pierce, SW Littler, DA Winkler, PV Bernhardt, C Pasay, JJ De Voss, J McCarthy, PG Parsons, GH Walter, et al.

Journal article  |  2018  |  Angewandte Chemie International Edition

A Combined In Vivo HSC Transduction/Selection Approach Results in Efficient and Stable Gene Expression in Peripheral Blood Cells in Mice

H Wang, M Richter, N Psatha, C Li, J Kim, J Liu, A Ehrhardt, SK Nilsson, B Cao, D Palmer, P Ng, Z Izsvák, KG Haworth, HP Kiem, T Papayannopoulou, A Lieber

Journal article  |  2018  |  Molecular Therapy - Methods & Clinical Development

Effector CD4( ) T cells recognize intravascular antigen presented by patrolling monocytes

Clare LV Westhorpe, M Ursula Norman, Pam Hall, Sarah L Snelgrove, Michaela Finsterbusch, Anqi Li, Camden Lo, Zhe Hao Tan, Songhui Li, Susan K Nilsson, A Richard Kitching, Michael J Hickey

Journal article  |  2018  |  Nature Communications

Effective macrophage delivery using RAFT copolymer derived nanoparticles

KS Montgomery, RWM Davidson, B Cao, B Williams, GW Simpson, SK Nilsson, J Chiefari, MJ Fuchter

Journal article  |  2018  |  Polymer Chemistry

Cell Type of Origin Dictates the Route to Pluripotency

Christian M Nefzger, Fernando J Rossello, Joseph Chen, Xiaodong Liu, Anja S Knaupp, Jaber Firas, Jacob M Paynter, Jahnvi Pflueger, Sam Buckberry, Sue Mei Lim, Brenda Williams, Sara Alaei, Keshav Faye-Chauhan, Enrico Petretto, Susan K Nilsson, Ryan Lister, Mirana Ramialison, David R Powell, Owen JL Rackham, Jose M Polo

Journal article  |  2017  |  Cell Reports

Niche Extracellular Matrix Components and Their Influence on HSC

Melanie J Domingues, Huimin Cao, Shen Y Heazlewood, Benjamin Cao, Susan K Nilsson

Journal article  |  2017  |  Journal of Cellular Biochemistry

New agents in HSC mobilization

Meanie Domingues, Susan Nilsson, Benjamin Cao

Journal article  |  2017  |  International Journal of Hematology

Factors that influence a mobilized HSC product

Susan Nilsson

Journal article  |  2017  |  International Journal of Hematology

Progress in bio-manufacture of platelets for transfusion

Shen Y Heazlewood, Susan K Nilsson, Kellie Cartledge, Cheang Ly Be, Andrew Vinson, Murat Gel, David N Haylock

Journal article  |  2017  |  Platelets

MED12 in hematopoietic stem cells - Cell specific function despite ubiquitous expression

MC Keightley, SK Nilsson, GJ Lieschke

Journal article  |  2017  |  Stem Cell Investigation

MOZ (KAT6A) is essential for the maintenance of classically defined adult hematopoietic stem cells

Bilal N Sheikh, Yuqing Yang, Jaring Schreuder, Susan K Nilsson, Rebecca Bilardi, Sebastian Carotta, Helen M McRae, Donald Metcalf, Anne K Voss, Tim Thomas

Journal article  |  2016  |  Blood

Differentiation of human embryonic stem cells to HOXA( ) hemogenic vasculature that resembles the aorta-gonad-mesonephros

Elizabeth S Ng, Lisa Azzola, Freya F Bruveris, Vincenzo Calvanese, Belinda Phipson, Katerina Vlahos, Claire Hirst, Vanta J Jokubaitis, Qing C Yu, Jovana Maksimovic, Simone Liebscher, Vania Januar, Zhen Zhang, Brenda Williams, Aude Conscience, Jennifer Durnall, Steven Jackson, Magdaline Costa, David Elliott, David N Haylock, et al.

Journal article  |  2016  |  Nature Biotechnology

Autophagy-dependent regulatory T cells are critical for the control of graft-versus-host disease

Laetitia Le Texier, Katie E Lineburg, Benjamin Cao, Cameron McDonald-Hyman, Lucie Leveque-El Mouttie, Jemma Nicholls, Michelle Melino, Blessy C Nalkurthi, Kylie A Alexander, Bianca Teal, Stephen J Blake, Fernando Souza-Fonseca-Guimaraes, Christian R Engwerda, Rachel D Kuns, Steven W Lane, Michele Teng, Charis Teh, Daniel Gray, Andrew D Clouston, Susan K Nilsson, et al.

Journal article  |  2016  |  JCI Insight

New method for harvesting stem cells could improve donor-patient treatment.

Susan Nilsson, Benjamin Cao

Journal article  |  2016  |  Medical Journal of Australia

Haemopedia: An Expression Atlas of Murine Hematopoietic Cells

Carolyn A De Graaf, Jarny Choi, Tracey M Baldwin, Jessica E Bolden, Kirsten A Fairfax, Aaron J Robinson, Christine Biben, Clare Morgan, Kerry Ramsay, Ashley P Ng, Maria Kauppi, Elizabeth A Kruse, Tobias J Sargeant, Nick Seidenman, Angela D'Amico, Marthe C D'Ombrain, Erin C Lucas, Sandra Koernig, Adriana Baz Morelli, Michael J Wilson, et al.

Journal article  |  2016  |  STEM CELL REPORTS

i-bodies, Human Single Domain Antibodies That Antagonize Chemokine Receptor CXCR4

Katherine Griffiths, Olan Dolezal, Benjamin Cao, Susan K Nilsson, Heng B See, Kevin DG Pfleger, Michael Roche, Paul R Gorry, Andrew Pow, Katerina Viduka, Kevin Lim, Bernadine GC Lu, Denison HC Chang, Thomas Murray-Rust, Marc Kvansakul, Matthew A Perugini, Con Dogovski, Marcel Doerflinger, Yuan Zhang, Kathy Parisi, et al.

Journal article  |  2016  |  Journal of Biological Chemistry

Validating Eaton's Hypothesis: Cubane as a Benzene Bioisostere

Benjamin A Chalmers, Hui Xing, Sevan Houston, Charlotte Clark, Sussan Ghassabian, Andy Kuo, Benjamin Cao, Andrea Reitsma, Cody-Ellen P Murray, Jeanette E Stok, Glen M Boyle, Carly J Pierce, Stuart W Littler, David A Winkler, Paul V Bernhardt, Cielo Pasay, James J De Voss, James McCarthy, Peter G Parsons, Gimme H Walter, et al.

Journal article  |  2016  |  Angewandte Chemie International Edition

Therapeutic targeting and rapid mobilization of endosteal HSC using a small molecule integrin antagonist

Benjamin Cao, Zhen Zhang, Jochen Grassinger, Brenda Williams, Chad K Heazlewood, Quentin I Churches, Simon A James, Songhui Li, Thalia Papayannopoulou, Susan K Nilsson

Journal article  |  2016  |  Nature Communications

The role of CD44 in fetal and adult hematopoietic stem cell regulation

Huimin Cao, Shen Y Heazlewood, Brenda Williams, Daniela Cardozo, Julie Nigro, Ana Oteiza, Susan K Nilsson

Journal article  |  2016  |  Haematologica

Brief Report: Factors Released by Megakaryocytes Thrombin Cleave Osteopontin to Negatively Regulate Hematopoietic Stem Cells

Melonie J Storan, Shen Y Heazlewood, Chad K Heazlewood, David N Haylock, Warren S Alexander, Rebecca J Neaves, Ana Oteiza, Susan K Nilsson

Journal article  |  2015  |  STEM CELLS

Isolation of Murine Bone Marrow Scavenging Sinusoidal Endothelial Cells

Peter AG McCourt, Ana Oteiza, Benjamin Cao, Susan K Nilsson

Journal article  |  2015  |  Methods in Molecular Biology

Design, synthesis and binding properties of a fluorescent alpha(9)beta(1)/alpha(4)beta(1) integrin antagonist and its application as an in vivo probe for bone marrow haemopoietic stem cells

Benjamin Cao, Oliver E Hutt, Zhen Zhang, Songhui Li, Shen Y Heazlewood, Brenda Williams, Jessica A Smith, David N Haylock, G Paul Savage, Susan K Nilsson

Journal article  |  2014  |  Org. Biomol. Chem.

Investigating the Interaction Between Hematopoietic Stem Cells and Their Niche During Embryonic Development: Optimizing the Isolation of Fetal and Newborn Stem Cells From Liver, Spleen, and Bone Marrow

Huimin Cao, Brenda Williams, Susan K Nilsson

Journal article  |  2014  |  Methods in Molecular Biology

Analyzing hematopoietic stem cell homing, lodgment, and engraftment to better understand the bone marrow niche

Shen Y Heazlewood, Ana Oteiza, Huimin Cao, Susan K Nilsson

Conference Proceedings  |  2014  |  Annals of the New York Academy of Sciences

The role of Tenascin C in the lymphoid progenitor cell niche

Sarah L Ellis, Shen Y Heazlewood, Brenda Williams, Andrea J Reitsma, Jochen Grassinger, Judy Borg, Chad K Heazlewood, Ann P Chidgey, Susan K Nilsson

Journal article  |  2013  |  EXPERIMENTAL HEMATOLOGY

Understanding the role of the microenvironment during definitive hemopoietic development

Huimin Cao, Ana Oteiza, Susan K Nilsson

Journal article  |  2013  |  Experimental Hematology

Megakaryocytes co-localise with hemopoietic stem cells and release cytokines that up-regulate stem cell proliferation

Shen Y Heazlewood, Rebecca J Neaves, Brenda Williams, David N Haylock, Timothy E Adams, Susan K Nilsson

Journal article  |  2013  |  Stem Cell Research

Potent Agonists of a Hematopoietic Stem Cell Cytokine Receptor, c-Mpl

Anna Tarasova, David N Haylock, Laurence Meagher, Cheang Ly Be, Jacinta White, Susan K Nilsson, Jessica Andrade, Kellie Cartledge, David A Winkler

Journal article  |  2013  |  ChemMedChem

The Prospective Isolation of Viable, High Ploidy Megakaryocytes from Adult Murine Bone Marrow by Fluorescence Activated Cell Sorting

Shen Y Heazlewood, Brenda Williams, Melonie J Storan, Susan K Nilsson

Journal article  |  2013  |  Methods in Molecular Biology

Homing and engraftment of murine and human hematopoietic stem and progenitor cells are mediated by junctional adhesion molecule A

C Hart, G Mueller, J Raithel, B Williams, R Andreesen, SK Nilsson, J Grassinger

Conference Proceedings  |  2012  |  ONKOLOGIE

Bone, microenvironment and hematopoiesis

Yi Shen, Susan K Nilsson

Journal article  |  2012  |  Current Opinion in Hematology

Granulocyte colony stimulating factor expands hematopoietic stem cells within the central but not endosteal bone marrow region

Jochen Grassinger, Brenda Williams, Gemma H Olsen, David N Haylock, Susan K Nilsson

Journal article  |  2012  |  Cytokine

The location and cellular composition of the hemopoietic stem cell niche

Sarah L Ellis, Susan K Nilsson

Journal article  |  2012  |  Cytotherapy

Mobilisation strategies for normal and malignant cells

L Bik To, Jean-Pierre Levesque, Kirsten E Herbert, Ingrid G Winkler, Linda J Bendall, Devendra K Hiwase, Vicki Antonenas, Alison M Rice, David Gottlieb, Anthony K Mills, John EJ Rasko, Stephen Larsen, Ashanka Beligaswatte, Susan K Nilsson, Julian P Cooney, Antony C Cambareri, Ian D Lewis

Journal article  |  2011  |  Pathology

The relationship between bone, hemopoietic stem cells, and vasculature

Sarah L Ellis, Jochen Grassinger, Allan Jones, Judy Borg, Todd Camenisch, David Haylock, Ivan Bertoncello, Susan K Nilsson

Journal article  |  2011  |  Blood

THE ROLE OF FRESHLY ISOLATED MEGAKARYOCYTES IN HAEMATOPOIETIC STEM CELL REGULATION

Y Shen, RJ Neaves, B Williams, CK Heazlewood, AJ Reitsma, DN Haylock, PA McCourt, SK Nilsson

Conference Proceedings  |  2011  |  EXPERIMENTAL HEMATOLOGY

Methods to Analyze the Homing Efficiency and Spatial Distribution of Hematopoietic Stem and Progenitor Cells and Their Relationship to the Bone Marrow Endosteum and Vascular Endothelium

Jochen Grassinger, Susie K Nilsson

Journal article  |  2011  |  Methods in molecular biology (Clifton, N.J.)

Phenotypically identical hemopoietic stem cells isolated from different regions of bone marrow have different biologic potential

Jochen Grassinger, David N Haylock, Brenda Williams, Gemma H Olsen, Susan K Nilsson

Journal article  |  2010  |  Blood

Homing, proliferation and mobilization of hematopoietic stem cells is regulated through the interaction of alpha(9)beta(1) and Osteopontin

J Grassinger, M Storan, B Williams, G Olsen, DN Haylock, SK Nilsson

Conference Proceedings  |  2010  |  ONKOLOGIE

THE PROTEIN KINASE ACTIVITY OF PHOSPHOINOSITIDE 3-KINASE ALPHA PROMOTES AUTONOMOUS CELL SURVIVAL IN AML STEM/PROGENITOR CELLS

D Thomas, JA Powell, EF Barry, J Woodcock, PG Ekert, BD Green, EM Lee, RB Lock, SK Nilsson, DN Haylock, AF Lopez, MA Guthridge

Conference Proceedings  |  2010  |  EXPERIMENTAL HEMATOLOGY

HEMATOPOIETIC STEM CELLS ARE REGULATED THROUGH THE INTERACTION OF ALPHA9 BETA1 AND OSTEOPONTIN

J Grassinger, M Storan, B Williams, G Olsen, D Sheppard, DN Haylock, SK Nilsson

Conference Proceedings  |  2010  |  EXPERIMENTAL HEMATOLOGY

ACTIVIN SIGNALLING MODULATION IS CRITICAL FOR NORMAL HEMATOPOIESIS IN ADULT MOUSE

KL Loveland, S Mithraprabhu, RJ Neaves, B Williams, GH Olsen, MM Matzuk, CW Brown, DN Haylock, SK Nilsson

Conference Proceedings  |  2010  |  EXPERIMENTAL HEMATOLOGY

TARGETING CELL SURVIVAL PATHWAYS IN ACUTE MYELOID LEUKEMIA

JA Powell, D Thomas, EF Barry, CH Kok, LY Ma, LB To, A Brown, ID Lewis, GJ Goodall, TP Speed, J Woodcock, M Osato, PG Ekert, DN Haylock, SK Nilsson, RJ D'Andrea, AF Lopez, MA Guthridge

Conference Proceedings  |  2010  |  EXPERIMENTAL HEMATOLOGY

UNDERSTANDING THE HSC NICHE

SK Nilsson

Conference Proceedings  |  2010  |  EXPERIMENTAL HEMATOLOGY

DESIGN, SYNTHESIS AND FUNCTION OF NOVEL AGONIST AND ANTAGONIST THROMBOPOIETIN MIMICS

DN Haylock, J Andrade, J White, SK Nilsson, L Meagher, T Cableswki, A Tarasova, CL Be, A Riches, D Winkler

Conference Proceedings  |  2010  |  EXPERIMENTAL HEMATOLOGY

COMPONENTS OF THE PROTHROMBINASE COMPLEX ARE EXPRESSED BY MEGAKARYOCYTES AND THE ENDOSTEAL REGION OF THE BONE MARROW NICHE

MJ Storan, DN Haylock, RJ Neaves, GA Whitty, A Dacumos-Hill, B Williams, SK Nilsson

Conference Proceedings  |  2010  |  EXPERIMENTAL HEMATOLOGY

THE ROLE OF FRESHLY ISOLATED MATURE MEGAKARYOCYTES IN REGULATING HSC FUNCTION IN VITRO AND IN VIVO

J Neaves, DN Haylock, Y Shen, SK Nilsson

Conference Proceedings  |  2010  |  EXPERIMENTAL HEMATOLOGY

The effect of bovine endosteum-derived particles on the proliferation of human mesenchymal stem cells

Julie Nigro, Jacinta F White, John AM Ramshaw, David N Haylock, Susan K Nilsson, Jerome A Werkmeister

Journal article  |  2010  |  Biomaterials

Expression profiling of a hemopoietic cell survival transcriptome implicates osteopontin as a functional prognostic factor in AML

Jason A Powell, Daniel Thomas, Emma F Barry, Chung H Kok, Barbara J McClure, Anna Tsykin, L Bik To, Anna Brown, Ian D Lewis, Kirsten Herbert, Gregory J Goodall, Terence P Speed, Norio Asou, Bindya Jacob, Motomi Osato, David N Haylock, Susan K Nilsson, Richard J D'Andrea, Angel F Lopez, Mark A Guthridge

Journal article  |  2009  |  Blood

An Innovative Triple Immunogold Labeling Method to Investigate the Hemopoietic Stem Cell Niche In Situ

Sarah L Ellis, Brenda Williams, Stephen Asquith, Ivan Bertoncello, Susan K Nilsson

Journal article  |  2009  |  Microscopy and Microanalysis

The osteoblastic niche following TBI

Susie Nilsson

Journal article  |  2009  |  Blood

LOCATION RATHER THAN PHENOTYPE IS CRITICAL FOR HSC FUNCTION

SK Nilsson, J Grassinger, G Haines, B Williams, DN Haylock

Conference Proceedings  |  2009  |  EXPERIMENTAL HEMATOLOGY

NOVEL THROMBOPOIETIN MIMICS FOR HAEMOPOIETIC STEM CELL EXPANSION

DN Haylock, J Andrade, J White, SK Nilsson, L Meagher, T Cableswki, K Schwab, A Tarasova, G Condie, A Riches, D Winkler

Conference Proceedings  |  2009  |  EXPERIMENTAL HEMATOLOGY

REGULATION OF MURINE HEMATOPOIETIC STEM CELLS BY MATURE MEGAKARYOCYTES IN THE ENDOSTEAL STEM CELL NICHE

RJ Neaves, DN Haylock, SK Nilsson

Conference Proceedings  |  2009  |  EXPERIMENTAL HEMATOLOGY

Thrombin-cleaved osteopontin regulates hemopoietic stem and progenitor cell functions through interactions with alpha(9)beta(1) and alpha(4)beta(1) integrins

Jochen Grassinger, David N Haylock, Melonie J Storan, Gemma O Haines, Brenda Williams, Genevieve A Whitty, Andrew R Vinson, Cheang Ly Be, Songhui Li, Esben S Sorensen, Patrick PL Tam, David T Denhardt, Dean Sheppard, Peter F Choong, Susan K Nilsson

Journal article  |  2009  |  Blood

Investigating the interactions between haemopoietic stem cells and their niche: methods for the analysis of stem cell homing and distribution within the marrow following transplantation.

Brenda Williams, Susan K Nilsson

Journal article  |  2009  |  Methods in Molecular Biology

Interactions between haemopoietic stem cells (HSC) and their microenvironment serve multiple functions including the attraction to..

Endogenous Fibroblastic Progenitor Cells in the Adult Mouse Lung Are Highly Enriched in the Sca-1 Positive Cell Fraction

Jonathan L McQualter, Nathalie Brouard, Brenda Williams, Brandi N Baird, Sunder Sims-Lucas, Karen Yuen, Susan K Nilsson, Paul J Simmons, Ivan Bertoncello

Journal article  |  2009  |  Stem Cells

Regulation of haemopoietic stem cells by OPN is mediated by specific interactions with alpha(4)beta(1) and alpha(9)beta(1) integrins

DN Haylock, M Storan, J Grassinger, B Williams, GA Whitty, T Uede, SK Nilsson

Conference Proceedings  |  2008  |  Cell Research

Defining the HSC niche: The relationship between bone, HSC and vasculature

Sarah L Ellis, Jochen Grassinger, Brenda Williams, Stephen Asquith, Gemina Haines, David Haylock, Susie K Nilsson

Conference Proceedings  |  2008  |  EXPERIMENTAL HEMATOLOGY

Hyaluronic acid synthesised by HAS-3 plays a critical role in HSC homing and regulation

David N Haylock, Jochen Grassinger, Brenda Williams, Gemma Haines, Susie K Nilsson

Conference Proceedings  |  2008  |  EXPERIMENTAL HEMATOLOGY

The cleaved form of osteopontin interactions with square(4)square(1) and square(9)square(1) integrins play a key role in regulating haemopoietic stem cell functions

Melonie Storan, David N Haylock, Jochen Grassinger, Brenda Williams, Gemma O Haines, Genevieve A Whitty, Susie K Nilsson

Conference Proceedings  |  2008  |  EXPERIMENTAL HEMATOLOGY

Blocking CD48 significantly decreases trans-endothelial migration of murine hematopoietic stem cells (HSC): Implications for homing and engraftment

Jochen Grassinger, Gemma Haines, Brenda Williams, David N Haylock, Susie K Nilsson

Conference Proceedings  |  2008  |  EXPERIMENTAL HEMATOLOGY

Defining the HSC niche: The relationship between bone, HSC and vasculature

Sarah L Ellis, Jochen Grassinger, Brenda Williams, Stephen Asquith, Gemma Haines, David Haylock, Susie K Nilsson

Conference Proceedings  |  2008  |  EXPERIMENTAL HEMATOLOGY

Osteopoietic stem cells: transplantable, but regeneratively limited

Susie Nilsson

Journal article  |  2008  |  Blood

Developmental fate determination and marker discovery in hematopoietic stem cell biology using proteomic fingerprinting

Elaine Spooncer, Nathalie Brouard, Susie K Nilsson, Brenda Williams, Mira C Liu, Richard D Unwin, David Blinco, Ewa Jaworska, Paul J Simmons, Anthony D Whetton

Journal article  |  2008  |  Molecular & Cellular Proteomics

Detection and quantification of functionally defined hematopoietic progenitor cells and tissue specific mRNA within the peripheral blood of myeloma patients after administration of granulocyte colony-stimulating factor and erythropoietin

Jochen Grassinger, Gunnar Mueller, Christina Hart, Susie K Nilsson, David N Haylock, Reinhard Andreesen, Burkhard Hennemann

Journal article  |  2008  |  European Journal of Haematology

Expansion of umbilical cord blood for clinical transplantation.

David N Haylock, Susan K Nilsson

Journal article  |  2007  |  Current Stem Cell Research & Therapy

Since the first successful cord blood transplant was performed in 1988 there has been a gradual increase in the use of cord blood ..

Hematopoietic progenitor cell mobilization results in hypoxia with increased hypoxia-inducible transcription factor-1 alpha and vascular endothelial growth factor A in bone marrow

Jean-Pierre Levesque, Ingrid G Winkler, Jean Hendy, Brenda Williams, Falak Helwani, Valerie Barbier, Bianca Nowlan, Susan K Nilsson

Journal article  |  2007  |  Stem Cells

Recent Australian experience with hemopoietic stem and progenitor cell expansion

SK Nilsson, HM Prince, D Wall, DN Haylock

Conference Proceedings  |  2007  |  Cytotherapy

Hematopoietic microenvironment and age

DN Haylock, SK Nilsson

Book Chapter  |  2007

Hemopoietic stem cells with higher hemopoietic potential reside at the bone marrow endosteum

David N Haylock, Brenda Williams, Hayley M Johnston, Mira CP Liu, Kate E Rutherford, Genevieve A Whitty, Paul J Simmons, Ivan Bertoncello, Susan K Nilsson

Journal article  |  2007  |  Stem Cells

Increased hypoxia, HIF-1 alpha protein and VEGF transcripts in bone marrow mobilized with G-CSF or cyclophosphamide (CY).

Jean-Pierre Levesque, Ingrid G Winkler, Jean Hendy, Susan K Nilsson

Conference Proceedings  |  2006  |  BLOOD

Interaction and regulation of HSC with osteopontin is mediated through alpha(4)beta(1) and alpha(9)beta(1) integrins, which are differentially expressed in the HSC pool.

David N Haylock, Genevieve A Whitty, Brenda Williams, Melome J Storan, Susie K Nilsson

Conference Proceedings  |  2006  |  Blood

708 the role of hyaluronic acid in normal and perturbed hemopoietic stem cell biology.

Sarah E Shaw, David N Haylock, Hayley M Johnston, Richard Lock, Susie K Nilsson

Conference Proceedings  |  2006  |  BLOOD

The integrins of alpha(4)beta(1) and alpha(9)beta(1) mediate interaction with and regulation of hemopoietic stem cells by osteopontin

DN Haylock, HM Johnston, GA Whittty, RJ Webb, SK Nilsson

Conference Proceedings  |  2006  |  EXPERIMENTAL HEMATOLOGY

The properties of candidate adult mouse lung progenitor cells isolated on the basis of Sca-1 antigen expression

Y Seyed Razavi, SK Nilsson, B Williams, K Rutherford, N Brouard, PJ Simmons, I Bertoncello

Conference Proceedings  |  2006  |  EXPERIMENTAL HEMATOLOGY

Hemopoietic stem cells within their niche

SK Nilsson

Conference Proceedings  |  2006  |  EXPERIMENTAL HEMATOLOGY

Osteopontin: a bridge between bone and blood

David N Haylock, Susan K Nilsson

Journal article  |  2006  |  British Journal of Haematology

Gene expression, synthesis and degradation of hyaluronan during differentiation of 3T3-L1 adipocytes

Peter G Allingham, Gary R Brownlee, Gregory S Harper, Minh Pho, Susan K Nilsson, Tracey J Brown

Journal article  |  2006  |  Archives of Biochemistry and Biophysics

The role of hyaluronic acid in hemopoietic stem cell biology

David N Haylock, Susan K Nilsson

Journal article  |  2006  |  Regenerative Medicine

Characterization and spatial localisation of candidate respiratory epithelial and stromal cell progenitor cells in the adult murine lung

YS Razavi, SK Nilsson, N Brouard, B Williams, K Rutherford, PJ Simmons, I Bertoncello

Conference Proceedings  |  2006  |  CYTOMETRY PART A

An optimal method for isolating murine haemopoietic stem cells; More cells with significantly enhanced haemopoietic potential

SK Nilsson, GA Whitty, I Bertoncello, B Williams, PJ Simmons, DN Haylock

Conference Proceedings  |  2006  |  CYTOMETRY PART A

Osteopontin regulates haemopoietic stem cells via alpha(4) beta(1) and alpha(9) beta(1) integrins

DN Haylock, GA Whitty, HM Johnston, B Williams, RJ Webb, I Bertoncello, PJ Simmons, SK Nilsson

Conference Proceedings  |  2006  |  CYTOMETRY PART A

Haemopoietic stem cells regulate their interaction with their niche by hyaluronic acid synthesis and degradation

DN Haylock, HM Johnston, T Brown, RJ Webb, B Williams, MCP Liu, KE Rutherford, SK Nilsson

Conference Proceedings  |  2006  |  CYTOMETRY PART A

The molecular characterisation of haemopoietic stem cells within their niche in situ

SL Ellis, S Asquith, H Johnston, W Brenda, SK Nilsson

Conference Proceedings  |  2006  |  CYTOMETRY PART A

Hemopoietic stem cell engraftment

SK Nilsson, PJ Simmons, I Bertoncello

Journal article  |  2006  |  Experimental Hematology

The over-expression of HAS2, Hyal-2 and CD44 is implicated in the invasiveness of breast cancer

L Udabage, GR Brownlee, SK Nilsson, TJ Brown

Journal article  |  2005  |  Experimental Cell Research

Stem cell regulation by the hematopoietic stem cell niche

DN Haylock, SK Nilsson

Journal article  |  2005  |  Cell Cycle

The identification and characterisation of transplanted hematopoietic stem cells in situ

SL Ellis, MP Palatsides, S Asquith, B Aisbett, HM Johnston, SK Nilsson

Conference Proceedings  |  2005  |  Microscopy and Microanalysis

Osteopontin, a key component of the hematopoietic stem cell niche and regulator of primitive hematopoietic progenitor cells

SK Nilsson, HM Johnston, GA Whitty, B Williams, RJ Webb, DT Denhardt, I Bertoncello, LJ Bendall, PJ Simmons, DN Haylock

Journal article  |  2005  |  Blood

Anti sense-mediated suppression of hyaluronan synthase 2 inhibits the tumorigenesis and progression of breast cancer

L Udabage, GR Brownlee, M Waltham, T Blick, EC Walker, P Heldin, SK Nilsson, EW Thompson, TJ Brown

Journal article  |  2005  |  Cancer Research

Vascular endothelial cells in mouse compact bone: A key component of the mesenchymal stem cell niche

BJ Short, SK Nilsson, N Brouard, HM Johnston, PJ Simmons

Conference Proceedings  |  2004  |  EXPERIMENTAL HEMATOLOGY

Hemopoietic stem cell lodgement in the stem cell niche

SK Nilsson

Conference Proceedings  |  2004  |  EXPERIMENTAL HEMATOLOGY

Role of CD44 variant exon 6 in acute lymphoblastic leukaemia: association with altered bone marrow localisation and increased tumour burden

LJ Bendall, SK Nilsson, NI Khan, A James, C Bonnet, RB Lock, R Papa, KF Bradstock, DJ Gottlieb

Journal article  |  2004  |  Leukemia

Transplantable stem cells: home to specific niches

SK Nilsson, PJ Simmons

Journal article  |  2004  |  Current Opinion in Hematology

Membrane-bound stem cell factor is a key regulator in the initial lodgment of stem cells within the endosteal marrow region

RL Driessen, HM Johnston, SK Nilsson

Journal article  |  2003  |  Experimental Hematology

Hyaluronan is synthesized by primitive hemopoietic cells, participates in their lodgment at the endosteum following transplantation, and is involved in the regulation of their proliferation and differentiation in vitro

SK Nilsson, DN Haylock, HM Johnston, T Occhiodoro, TJ Brown, PJ Simmons

Journal article  |  2003  |  Blood

Homing of purified murine lymphohematopoietic stem cells: A cytokine-induced defect

J Cerny, M Dooner, C McAuliffe, H Habibian, K Stencil, V Berrios, J Reilly, J Carlson, AM Cerny, L d'Hondt, B Benoit, JF Lambert, G Colvin, S Nilsson, P Becker, P Quesenberry

Journal article  |  2002  |  Journal of Hematotherapy & Stem Cell Research

Periwound dopaminergic sprouting is dependent on numbers of wound macrophages

PE Batchelor, MJ Porritt, SK Nilsson, I Bertoncello, GA Donnan, DW Howells

Journal article  |  2002  |  European Journal of Neuroscience

Vascular cell adhesion molecule-1 (CD 106) is cleaved by neutrophil proteases in the bone marrow following hematopoietic progenitor cell mobilization by granulocyte colony-stimulating factor

JP Levesque, Y Takamatsu, SK Nilsson, DN Haylock, PJ Simmons

Journal article  |  2001  |  Blood

Spatial localization of transplanted hemopoietic stem cells: inferences for the localization of stem cell niches

SK Nilsson, HM Johnston, JA Coverdale

Journal article  |  2001  |  Blood

Role of integrins and selectins in the development and regulation of the hematopoietic system

JP Lévesque, Y Takamatsu, SK Nilsson, DN Haylock, PJ Simmons

Journal article  |  2001  |  Hematologie

Mobilization of hemopoietic progenitor cells into peripheral blood is associated with vcam-1proteolytic cleavage in the bone marrow

JP Levesque, Y Takamatsu, SK Nilsson, DN Haylock, PJ Simmons

Journal article  |  2000  |  Blood

Mobilization of hemopoietic progenitor cells into peripheral blood is associated with VCAM-1 proteolytic cleavage in the-bone marrow.

JP Levesque, Y Takamatsu, SK Nilsson, DN Haylock, PJ Simmons

Conference Proceedings  |  2000  |  BLOOD

Evidence for endosteal hemopoietic stem cell niches: the spatial localisation of transplanted marrow cell sub-populations.

SK Nilsson, JA Coverdale

Conference Proceedings  |  1999  |  BLOOD

Dental abnormalities associated with failure of tooth eruption in src knockout and op/op mice

JC Tiffee, L Xing, S Nilsson, BF Boyce

Journal article  |  1999  |  Calcified Tissue International

Osteoblast-specific gene expression after transplantation of marrow cells: Implications for skeletal gene therapy

Z Hou, Q Nguyen, B Frenkel, SK Nilsson, M Milne, AJ van Wijnen, JL Stein, P Quesenberry, JB Lian, GS Stein

Journal article  |  1999  |  Proceedings of the National Academy of Sciences

Stem cell engraftment and cell cycle phenotype

P Quesenberry, P Becker, S Nilsson, M Stewart, S Zhong, C Grimaldi, J Reilly, H Hababian, M Dooner, S Peters, H Ramshaw

Journal article  |  1999  |  Leukemia

Adhesion receptor expression by hematopoietic cell lines and murine progenitors: Modulation by cytokines and cell cycle status

PS Becker, SK Nilsson, ZF Li, VM Berrios, MS Dooner, CL Cooper, CC Hsieh, PJ Quesenberry

Journal article  |  1999  |  Experimental Hematology

Cells capable of bone production engraft from whole bone marrow transplants in nonablated mice

SK Nilsson, MS Dooner, HU Weier, B Frenkel, JB Lian, GS Stein, PJ Quesenberry

Journal article  |  1999  |  Journal of Experimental Medicine

Lymphohematopoietic stem cell engraftment

PJ Quesenberry, FM Stewart, SJ Zhong, H Habibiani, C McAuliffe, J Reilly, J Carlson, M Dooner, S Nilsson, S Peters, G Stein, J Stein, R Emmons, B Benoit, I Bertoncello, P Becker

Conference Proceedings  |  1999  |  Annals of the New York Academy of Sciences

Lymphohematopoietic engraftment in minimally myeloablated hosts

FM Stewart, S Zhong, J Wuu, CC Hsieh, SK Nilsson, PJ Quesenberry

Journal article  |  1998  |  Blood

Immunofluorescence characterization of key extracellular matrix proteins in murine bone marrow in situ

SK Nilsson, ME Debatis, MS Dooner, JA Madri, PJ Quesenberry, PS Becker

Journal article  |  1998  |  Journal of Histochemistry & Cytochemistry

Chiaroscuro hematopoietic stem cell.

P Quesenberry, M Habibian, M Dooner, S Zhong, J Reilly, S Peters, P Becker, C Grimaldi, J Carlson, P Reddy, S Nilsson, FM Stewart

Journal article  |  1998  |  Transactions of the American Clinical and Climatological Association

These observations suggest several immediate clinical strategies. In gene therapy, approaches could be targeted to obtain cycling ..

Synchronized cell-cycle induction of engrafting long-term repopulating stem cells

SK Nilsson, MS Dooner, PJ Quesenberry

Journal article  |  1997  |  Blood

Osteoblast progenitors engraft from whole bone marrow transplants in nonablated mice

SK Nilsson, MS Dooner, HUG Weier, B Frenkel, JB Lian, US Stein, PJ Qucsenberrv

Journal article  |  1997  |  Experimental Hematology

Minimal myeloablation of the host increases THB competitive dominance of donor stem cells: implications for human gene therapy

FM Stewart, S Zhong, S Nilsson, PJ Quesenberry

Journal article  |  1997  |  Experimental Hematology

Osteoblast progenitors engraft from whole bone marrow transplants in nonablated mice.

SK Nilsson, MS Dooner, HUG Weier, B Frenkel, JB Lian, GS Stein, PJ Quesenberry

Conference Proceedings  |  1997  |  BLOOD

Rapid cell cycle induction of engrafting long-term repopulating stem cells.

SK Nilsson, MS Dooner, PJ Quesenberry

Conference Proceedings  |  1997  |  BLOOD

Stimulatory cytokines modulate adhesion receptor expression by murine LIN- SCA( ) cells and simultaneous blocking of alpha (L), alpha (4) and L-selectin inhibits hematopoietic progenitor cell-stromal cell interactions.

PS Becker, V Berrios, SK Nilsson, MS Dooner, N Banu, HS Ramshaw, PJ Quesenberry

Conference Proceedings  |  1997  |  BLOOD

Osteoblast progenitors engraft from whole bone marrow transplants in nonablated mice.

SK Nilsson, MS Dooner, HUG Weier, B Frenkel, JB Lian, GS Stein, PJ Quesenberry

Conference Proceedings  |  1997  |  EXPERIMENTAL HEMATOLOGY

Potential and distribution of transplanted hematopoietic stem cells in a nonablated mouse model

SK Nilsson, MS Dooner, CY Tiarks, HU Weier, PJ Quesenberry

Journal article  |  1997  |  Blood

Engraftment of hematopoietic stem cells in nonmyeloablated and myeloablated hosts

PJ Quesenberry, MF Stewart, S Peters, S Nillson, H Ramshaw, S Rao, C Tiarks, S Zhong, A Frimberger, J Reilly

Conference Proceedings  |  1997  |  Stem Cells

Homing of primitive stem cells into the marrow of nonablated murine hosts

SK Nilsson, MS Popper, CY Tiarks

Journal article  |  1996  |  Experimental Hematology

Antibody blocking of alpha(4) integrin has no effect on hematopoietic engraftment in nonmyeloablated, splenectomized mice.

PS Becker, HS Ramshaw, SK Nilsson, ME Debatis, GJ Riel, Z Li, PJ Quesenberry

Conference Proceedings  |  1996  |  BLOOD

Early events in the homing of murine hemopoietic stem cells.

SK Nilsson, MS Dooner, CY Tiarks, AE Frimberger, PJ Ouesenberry

Conference Proceedings  |  1996  |  BLOOD

Extracellular matrix regulation of stem cell homing.

SK Nilsson, ME Debatis, PJ Quesenberry, PS Becker

Conference Proceedings  |  1996  |  BLOOD

In situ detection of individual transplanted bone marrow cells using FISH on sections of paraffin-embedded whole murine femurs

SK Nilsson, R Hulspas, HUG Weier, PJ Quesenberry

Journal article  |  1996  |  Journal of Histochemistry & Cytochemistry

Homing of primitive stem cells into the marrow of nonablated murine hosts.

SK Nilsson, MS Dooner, CY Tiarks, HUG Weier, PJ Quesenberry

Conference Proceedings  |  1996  |  EXPERIMENTAL HEMATOLOGY

In vivo detection of individual transplanted bone marrow cells, using fish on sections of paraffin embedded murine femurs.

SK Nilsson, R Hulspas, HU Weier, PJ Ouesenberry

Conference Proceedings  |  1995  |  BLOOD

GRANULOCYTE-MACROPHAGE COLONY-STIMULATING FACTOR IS NOT RESPONSIBLE FOR HEMATOPOIETIC CORRECTIONS IN THE MATURING OP/OP MOUSE

SK NILSSON, GJ LIESCHKE, CC GARCIAWIJNEN, B WILLIAMS, D TZELEPIS, G HODGSON, D GRAIL, AR DUNN, I BERTONCELLO

Conference Proceedings  |  1995  |  EXPERIMENTAL HEMATOLOGY

GRANULOCYTE-MACROPHAGE COLONY-STIMULATING FACTOR IS NOT RESPONSIBLE FOR THE CORRECTION OF HEMATOPOIETIC DEFICIENCIES IN THE MATURING OP/OP MOUSE

SK NILSSON, GJ LIESCHKE, CC GARCIAWIJNEN, B WILLIAMS, D TZELEPIS, G HODGSON, D GRAIL, AR DUNN, I BERTONCELLO

Journal article  |  1995  |  Blood

HEMATOPOIETIC RADIOPROTECTION BY CREMOPHOR EL - A POLYETHOXYLATED CASTOR-OIL

I BERTONCELLO, AB KRIEGLER, DM WOODCOCK, B WILLIAMS, L BARBER, SK NILSSON

Journal article  |  1995  |  International Journal of Radiation Biology

THE OSTEOPETROTIC (OP/OP) MOUSE - A MODEL OF HEMATOPOIETIC STEM-CELLS IN DIFFERENT BUT ALTERING MICROENVIRONMENTS

SK NILSSON, I BERTONCELLO

Conference Proceedings  |  1994  |  EXPERIMENTAL HEMATOLOGY

A SYSTEMATIC HISTOMORPHOMETRIC ANALYSIS OF OSTEOCLASTS IN THE MATURING OSTEOPETROTIC (OP/OP) MOUSE

SK NILSSON, I BERTONCELLO, H CHEN, BF BOYCE

Conference Proceedings  |  1994  |  EXPERIMENTAL HEMATOLOGY

THE DEVELOPMENT AND ESTABLISHMENT OF HEMATOPOIESIS IN FETAL AND NEWBORN OSTEOPETROTIC (OP/OP) MICE

SK NILSSON, I BERTONCELLO

Journal article  |  1994  |  Developmental Biology

AGE-RELATED-CHANGES IN EXTRAMEDULLARY HEMATOPOIESIS IN THE SPLEEN OF NORMAL AND PERTURBED OSTEOPETROTIC (OP/OP) MICE (VOL 22, PG 380, 1994)

SK NILSSON, I BERTONCELLO

Journal article  |  1994  |  EXPERIMENTAL HEMATOLOGY

AGE-RELATED-CHANGES IN EXTRAMEDULLARY HEMATOPOIESIS IN THE SPLEEN OF NORMAL AND PERTURBED OSTEOPETROTIC (OP/OP) MICE

SK NILSSON, I BERTONCELLO

Journal article  |  1994  |  Experimental Hematology

Erratum: Age-related changes in extramedullary hematopoiesis in the spleen of normal and perturbed osteopetrotic (op/op) mice (Experimental Hematology (April 1994, Volume 22, Number 4, (380-381))

SK Nilsson, I Bertoncello

Journal article  |  1994  |  Experimental Hematology

OSTEOCLAST DEFICIENCIES IN OSTEOPETROTIC (OP/OP) MICE ARE NOT PERMANENT, BUT CORRECT WITH AGE IN THE ABSENCE OF COLONY-STIMULATING FACTOR-I (CSF-1)

SK NILSSON, I BERTONCELLO

Conference Proceedings  |  1993  |  EXPERIMENTAL HEMATOLOGY

THE HEMATOPOIETIC DEFICIENCIES IN OSTEOPETROTIC (OP/OP) MICE ARE NOT PERMANENT, BUT PROGRESSIVELY CORRECT WITH AGE

SK BEGG, I BERTONCELLO

Journal article  |  1993  |  Experimental Hematology

DELAYED HEMATOPOIETIC DEVELOPMENT IN OSTEOPETROTIC (OP/OP) MICE

SK BEGG, JM RADLEY, JW POLLARD, OT CHISHOLM, ER STANLEY, I BERTONCELLO

Journal article  |  1993  |  The Journal of Experimental Medicine

THE ESTABLISHMENT OF HEMATOPOIESIS IN FETAL AND NEWBORN OSTEOPETROTIC (OP OP) MICE

SK NILSSON, I BERTONCELLO

Conference Proceedings  |  1993  |  JOURNAL OF LEUKOCYTE BIOLOGY

MACROPHAGE DEVELOPMENT, AND AGE-RELATED-CHANGES IN HEMATOPOIESIS, IN CSF-1 DEFICIENT OSTEOPETROTIC (OP/OP) MICE

SK BEGG, JM RADLEY, JW POLLARD, O CHISHOLM, ER STANLEY, I BERTONCELLO

Conference Proceedings  |  1992  |  EXPERIMENTAL HEMATOLOGY

Primate-specific response of astrocytes to stroke limits peripheral macrophage infiltration

Anthony G Boghdadi, Joshua Spurrier, Leon Teo, Mingfeng Li, Mario Skarica, Benjamin Cao, William Kwan, Tobias D Merson, Susie K Nilsson, Nenad Sestan, Stephen M Strittmatter, James A Bourne

Journal article

Reactive astrocytes play critical roles after brain injuries but their precise function in stroke is not well defined. Here, we ut..