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Paul Gooley

Professor And Reader
Protein Structure and Function
science & technology
life sciences & biomedicine
biochemistry & molecular biology
magnetic resonance spectroscopy
amino acid sequence
molecular sequence data
Paul Gooley's Profile Picture

Paul Gooley

Medicine, Dentistry And Health Sciences
Primary Interest
Nuclear Magnetic Resonance Specroscopy
Paul Gooley's Profile Picture

Paul Gooley


Paul Gooley is an Associate Professor in Biochemistry and Molecular Biology at the University of Melbourne. Paul is expert in solution nuclear magnetic resonance spectroscopy especially applied to proteins.

He trained with Ray Norton at the University of New South Wales before going to the USA for postdoctoral studies with Ian Armitage at Yale and Neil MacKenzie at the University of Arizona. He worked at Merck and Co. in a structural biology group before returning to Australia in 1996 to form his research group at the University of Melbourne. He played a critical role in establishing the NMR facility (cave) at the Bio21 Institute in preparing ARC LIEF grants for the 600 and 700 MHz biological spectrometers. He applies NMR techniques to understand how proteins work focusing on defining ligand binding sites and understanding the conformational changes that occur on ligand binding. Current interests are in the molecular mechanism of activation of G-protein coupled receptors, especially the relaxin receptor (RXFP1), and the structure and function of lyssavirus (rabies) proteins, particularly the intrinsically disordered P-protein and its role in suppressing the innate immune response.


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Project Types


Research Grant


Internal Research Grant


Research Contracts

Scholarly Works

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Professor And Reader

Biochemistry And Molecular Biology

Academic Teaching And Research

Bio21 Institute

No Data

Australian and New Zealand Society for Magnetic Resonance

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Australian Socciety for Biochemistry and Molecular Biology


Doctor of Philosophy

University of New South Wales

Bachelor of Science

University of New South Wales