Yu-Yen Chen

Self-assembly of dental surface nanofilaments and remineralisation by SnF2 and CPP-ACP nanocomplexes

James R Fernando, Peiyan Shen, Christina PC Sim, Yu-Yen Chen, Glenn D Walker, Yi Yuan, Coralie Reynolds, David P Stanton, Colin M MacRae, Eric C Reynolds

Journal article  |  2019  |  Scientific Reports

Molecular Interactions of Peptide Encapsulated Calcium Phosphate Delivery Vehicle at Enamel Surfaces

NL Huq, KJ Cross, H Myroforidis, DP Stanton, YY Chen, BR Ward, EC Reynolds

Book Chapter  |  2018

Phosphorylated peptides derived from milk caseins, known as casein phosphopeptides (CPP) self-assemble and encapsulate the calcium..

Porphyromonas gingivalis Gingipains Display Transpeptidation Activity

Lianyi Zhang, Paul D Veith, N Laila Huq, Yu-Yen Chen, Christine A Seers, Keith J Cross, Dhana G Gorasia, Eric C Reynolds

Journal article  |  2018  |  Journal of Proteome Research

Combating multidrug-resistant Gram-negative bacteria with structurally nanoengineered antimicrobial peptide polymers

Shu J Lam, Neil M O'Brien-Simpson, Namfon Pantarat, Adrian Sulistio, Edgar HH Wong, Yu-Yen Chen, Jason C Lenzo, James A Holden, Anton Blencowe, Eric C Reynolds, Greg G Qiao

Journal article  |  2016  |  Nature Microbiology

PG1058 Is a Novel Multidomain Protein Component of the Bacterial Type IX Secretion System

Jacqueline E Heath, Christine A Seers, Paul D Veith, Catherine A Butler, Nor A Nor Muhammad, Yu-Yen Chen, Nada Slakeski, Benjamin Peng, Lianyi Zhang, Stuart G Dashper, Keith J Cross, Steven M Cleal, Caroline Moore, Eric C Reynolds

Journal article  |  2016  |  PLOS ONE

Spheres of influence: Porphyromonas gingivalis outer membrane vesicles

MJ Gui, SG Dashper, N Slakeski, Y-Y Chen, EC Reynolds

Journal article  |  2016  |  Molecular Oral Microbiology

TARGETING AND KILLING MULTIDRUG-RESISTANT BACTERIA WITH POLYPEPTIDE STAR NANOPARTICLES

N O'Brien-Simpson, S Lam, N Pantarat, A Sulistio, E Wong, Y-Y Chen, J Lenzo, J Holden, A Blencowe, G Qiao, E Reynolds

Conference Proceedings  |  2016  |  JOURNAL OF PEPTIDE SCIENCE

Differential Responses of Pattern Recognition Receptors to Outer Membrane Vesicles of Three Periodontal Pathogens

Jessica D Cecil, Neil M O'Brien-Simpson, Jason C Lenzo, James A Holden, Yu-Yen Chen, William Singleton, Katelyn T Gause, Yan Yan, Frank Caruso, Eric C Reynolds

Journal article  |  2016  |  PLOS ONE

Tannerella forsythia Outer Membrane Vesicles Are Enriched with Substrates of the Type IX Secretion System and TonB-Dependent Receptors

Paul D Veith, Yu-Yen Chen, Dina Chen, Neil M O'Brien-Simpson, Jessica D Cecil, James A Holden, Jason C Lenzo, Eric C Reynolds

Journal article  |  2015  |  Journal of Proteome Research

Porphyromonas gingivalis Type IX Secretion Substrates Are Cleaved and Modified by a Sortase-Like Mechanism

Dhana G Gorasia, Paul D Veith, Dina Chen, Christine A Seers, Helen A Mitchell, Yu-Yen Chen, Michelle D Glew, Stuart G Dashper, Eric C Reynolds

Journal article  |  2015  |  PLOS Pathogens

SNAPPing Gram-negative bacteria with star-shaped polypeptides

Shu Jie Lam, Neil O'Brien-Simpson, Namfon Pantarat, Adrian Sulistio, Edgar Hoe Hon Wong, Yu-Yen Chen, Anton Blencowe, Eric Reynolds, Greg Qiao

Conference Proceedings  |  2015  |  ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY

Blue native-PAGE analysis of membrane protein complexes in Porphyromonas gingivalis

Michelle D Glew, Paul D Veith, Dina Chen, Christine A Seers, Yu-Yen Chen, Eric C Reynolds

Journal article  |  2014  |  Journal of Proteomics

Porphyromonas gingivalis Outer Membrane Vesicles Exclusively Contain Outer Membrane and Periplasmic Proteins and Carry a Cargo Enriched with Virulence Factors

Paul D Veith, Yu-Yen Chen, Dhana G Gorasia, Dina Chen, Michelle D Glew, Neil M O'Brien-Simpson, Jessica D Cecil, James A Holden, Eric C Reynolds

Journal article  |  2014  |  Journal of Proteome Research

Porphyromonas gingivalis and Treponema denticola Synergistic Polymicrobial Biofilm Development

Ying Zhu, Stuart G Dashper, Yu-Yen Chen, Simon Crawford, Nada Slakeski, Eric C Reynolds

Journal article  |  2013  |  PLoS One

Reversible redox regulation of specificityof Arg-gingipain B in Porphyromonas gingivalis

Yu-Yen Chen, Christine A Seers, Nada Slakeski, Caroline Moore, Lianyi Zhang, Eric C Reynolds

Journal article  |  2013  |  FEBS Letters

Metallocarboxypeptidase G (Porphyromonas gingivalis)

Yu-Yen Chen, Keith J Cross, Eric C Reynolds

Book Chapter  |  2013

Differential Proteomic Analysis of a Polymicrobial Biofilm

Zamirah Zainal-Abidin, Paul D Veith, Stuart G Dashper, Ying Zhu, Deanne V Catmull, Yu-Yen Chen, Deasy C Heryanto, Dina Chen, James S Pyke, Kheng Tan, Helen L Mitchell, Eric C Reynolds

Journal article  |  2012  |  Journal of Proteome Research

PG0026 Is the C-terminal Signal Peptidase of a Novel Secretion System of Porphyromonas gingivalis

Michelle D Glew, Paul D Veith, Benjamin Peng, Yu-Yen Chen, Dhana G Gorasia, Qiaohui Yang, Nada Slakeski, Dina Chen, Caroline Moore, Simon Crawford, Eric C Reynolds

Journal article  |  2012  |  Journal of Biological Chemistry

Lactoferrin Inhibits Porphyromonas gingivalis Proteinases and Has Sustained Biofilm Inhibitory Activity

Stuart G Dashper, Yu Pan, Paul D Veith, Yu-Yen Chen, Elena CY Toh, Sze Wei Liu, Keith J Cross, Eric C Reynolds

Journal article  |  2012  |  Antimicrobial Agents and Chemotherapy

The outer membrane protein LptO is essential for the O-deacylation of LPS and the co-ordinated secretion and attachment of A-LPS and CTD proteins in Porphyromonas gingivalis

Yu-Yen Chen, Benjamin Peng, Qiaohui Yang, Michelle D Glew, Paul D Veith, Keith J Cross, Kenneth N Goldie, Dina Chen, Neil O'Brien-Simpson, Stuart G Dashper, Eric C Reynolds

Journal article  |  2011  |  Molecular Microbiology

Porphyromonas gingivalis Cysteine Proteinase Inhibition by kappa-Casein Peptides

Elena CY Toh, Stuart G Dashper, N Laila Huq, Troy J Attard, Neil M O'Brien-Simpson, Yu-Yen Chen, Keith J Cross, David P Stanton, Rita A Paolini, Eric C Reynolds

Journal article  |  2011  |  Antimicrobial Agents and Chemotherapy

Characterization of hemin-binding protein 35 (HBP35) in Porphyromonas gingivalis: its cellular distribution, thioredoxin activity and role in heme utilization

Mikio Shoji, Yasuko Shibata, Teruaki Shiroza, Hideharu Yukitake, Benjamin Peng, Yu-Yen Chen, Keiko Sato, Mariko Naito, Yoshimitsu Abiko, Eric C Reynolds, Koji Nakayama

Journal article  |  2010  |  BMC Microbiology

Mass Spectrometric Analyses of Peptides and Proteins in Human Gingival Crevicular Fluid

Luan H Ngo, Paul D Veith, Yu-Yen Chen, Dina Chen, Ivan B Darby, Eric C Reynolds

Journal article  |  2010  |  Journal of Proteome Research

The RgpA-Kgp Proteinase-Adhesin Complexes of Porphyromonas gingivalis Inactivate the Th2 Cytokines Interleukin-4 and Interleukin-5

Vivian Tam, Neil M O'Brien-Simpson, Yu-Yen Chen, Colin J Sanderson, Beverley Kinnear, Eric C Reynolds

Journal article  |  2009  |  Infection and Immunity

The RgpB C-terminal domain has a role in attachment of RgpB to the outer membrane and belongs to a novel C-terminal-domain family found in Porphyromonas gingivalis

Christine A Seers, Nada Slakeski, Paul D Veith, Todd Nikolof, Yu-Yen Chen, Stuart G Dashper, Eric C Reynolds

Journal article  |  2006  |  Journal of Bacteriology

Characterization of the fluoroacetate detoxication enzymes of rat liver cytosol

LQ Tu, YY Chen, PFA Wright, CJ Rix, R Bolton-Grob, JT Ahokas

Journal article  |  2005  |  Xenobiotica

An immune response directed to proteinase and adhesin functional epitopes protects against Porphyromonas gingivalis-induced periodontal bone loss

NM O'Brien-Simpson, RD Pathirana, RA Paolini, YY Chen, PD Veith, V Tam, N Ally, RN Pike, EC Reynolds

Journal article  |  2005  |  Journal of Immunology

Association of bovine dentine phosphophoryn with collagen fragments

NL Huq, A Loganathan, KJ Cross, YY Chen, NI Johnson, M Willetts, PD Veith, EC Reynolds

Journal article  |  2005  |  Archives of Oral Biology

Porphyromonas gingivalis RgpA and Kgp proteinases and adhesins are C terminally processed by the carboxypeptidase CPG70

PD Veith, YY Chen, EC Reynolds

Journal article  |  2004  |  Infection and Immunity

CPG70 is a novel basic metallocarboxypeptidase with C-terminal polycystic kidney disease domains from Porphyromonas gingivalis

YY Chen, KJ Cross, RA Paolini, JE Fielding, N Slakeski, EC Reynolds

Journal article  |  2002  |  Journal of Biological Chemistry