Dr Padma Murthi

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Padma Murthi's highlights

FEATURED Journal article

Increased decidual mRNA expression levels of candidate maternal preeclampsia susceptibility genes are associated with clinical severity

Understanding The Role Of Endogenous And Pharmacologic Glycosaminoglycans In Preventing Pr..
Research Grant
Control of extravillous trophoblast function by the eotaxins CCL11, CCL24 and CCL26
Journal article
What Controls Blood Vessel Changes In A Mother During Pregnancy?
Research Grant
Decidual mesenchymal stem/stromal cell-derived extracellular vesicles ameliorate endotheli..
Journal article
Understanding How Proteoglycans In The Placenta Cause Restriction Of Fetal Growth
Research Grant
Hydroxychloroquine Mitigates the Production of 8-Isoprostane and Improves Vascular Dysfunc..
Journal article

Padma Murthi's selected work

Understanding The Role Of Endogenous And Pharmacologic Glycosaminoglycans In Preventing Pr..

Research Grant

Control of extravillous trophoblast function by the eotaxins CCL11, CCL24 and CCL26

Journal article

What Controls Blood Vessel Changes In A Mother During Pregnancy?

Research Grant

Decidual mesenchymal stem/stromal cell-derived extracellular vesicles ameliorate endotheli..

Journal article

Understanding How Proteoglycans In The Placenta Cause Restriction Of Fetal Growth

Research Grant

Hydroxychloroquine Mitigates the Production of 8-Isoprostane and Improves Vascular Dysfunc..

Projects

Displaying the 6 most recent projects by Padma Murthi.

Understanding The Role Of Endogenous And Pharmacologic Glycosaminoglycans In Preventing Pre-Eclampsia

Pre-eclampsia (PE) is a serious pregnancy complication that affects the well being of the mother and baby. There is no cure for PE except fo..

2013 - 2017

Completed

What Controls Blood Vessel Changes In A Mother During Pregnancy?

2011 - 2012

Completed

Understanding How Proteoglycans In The Placenta Cause Restriction Of Fetal Growth

Fetal growth restriction (FGR) is a pregnancy complication in which the baby doesn�t grow properly in the womb. Growth restricted babies are..

2011 - 2013

Completed

The role of growth control genes in disorders of the placenta.

We must understand the role of growth control genes in the growth of the human placenta. The reason is that in several significant placental..

2008 - 2010

Completed

Understanding The Molecular Mechanism Of Fetal Growth Restriction; A Pregnancy Disorder That Prevents A Healthy Start To Life

The Role Of Growth Control Genes In Disorders Of The Placenta.

6

Projects

Project Types

Research Grant

Internal Research Grant

Scholarly Works

Displaying the 121 most recent scholarly works by Padma Murthi.

Decidual mesenchymal stem/stromal cell-derived extracellular vesicles ameliorate endothelial cell proliferation, inflammation, and oxidative stress in a cell culture model of preeclampsia.

Shixuan Zheng, Aiwu Shi, Sophia Hill, Claire Grant, Maria I Kokkinos, Padma Murthi, Harry M Georgiou, Shaun P Brennecke, Bill Kalionis

Journal article | 2020 | Pregnancy Hypertension

Oxidative stress and endothelial dysfunction contribute substantially to the pathogenesis of preeclampsia (PE). Decidual mesenchym..

Hydroxychloroquine Mitigates the Production of 8-Isoprostane and Improves Vascular Dysfunction: Implications for Treating Preeclampsia

Rahana Abd Rahman, Padma Murthi, Harmeet Singh, Seshini Gurungsinghe, Bryan Leaw, Joanne C Mockler, Rebecca Lim, Euan M Wallace

Journal article | 2020 | International Journal of Molecular Sciences

In preeclampsia, widespread maternal endothelial dysfunction is often secondary to excessive generation of placental-derived anti-..

Decreased Placental FPR2 in Early Pregnancies That Later Developed Small-For-Gestation Age: A Potential Role of FPR2 in the Regulation of Epithelial-Mesenchymal Transition

Padma Murthi, Gayathri Rajaraman, Jan Jaap HM Erwich, Evdokia Dimitriadis

Journal article | 2020 | Cells

We reported earlier that an anti-inflammatory small peptide receptor-formyl peptide receptor-2 (FPR2) was significantly decreased ..

The Effects of Early-Onset Pre-Eclampsia on Placental Creatine Metabolism in the Third Trimester

Stacey J Ellery, Padma Murthi, Paul A Della Gatta, Anthony K May, Miranda L Davies-Tuck, Greg M Kowalski, Damien L Callahan, Clinton R Bruce, Euan M Wallace, David W Walker, Hayley Dickinson, Rod J Snow

Journal article | 2020 | International Journal of Molecular Sciences

Creatine is a metabolite important for cellular energy homeostasis as it provides spatio-temporal adenosine triphosphate (ATP) buf..

Placental serotonin systems in pregnancy metabolic complications associated with maternal obesity and gestational diabetes mellitus

Padma Murthi, Cathy Vaillancourt

Journal article | 2020 | Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease

Serotonin (5-hydroxytryptamine, 5-HT) regulates diverse physiological and behavioural and processes, also acts as a developmental ..

Inflammasomes-A Molecular Link for Altered Immunoregulation and Inflammation Mediated Vascular Dysfunction in Preeclampsia

Padma Murthi, Anita A Pinar, Evdokia Dimitriadis, Chrishan S Samuel

Journal article | 2020 | International Journal of Molecular Sciences

Preeclampsia (PE) is a pregnancy-specific multisystem disorder and is associated with maladaptation of the maternal cardiovascular..

Disrupted placental serotonin synthetic pathway and increased placental serotonin: Potential implications in the pathogenesis of human fetal growth restriction

Suveena Ranzil, Stacey Ellery, David W Walker, Cathy Vaillancourt, Nadia Alfaidy, Alexander Bonnin, Anthony Borg, Euan M Wallace, Peter R Ebeling, Jan Jaap Erwich, Padma Murthi

Journal article | 2019 | Placenta

OBJECTIVES: Placental insufficiency contributes to altered maternal-fetal amino acid transfer, and thereby to poor fetal growth. A..

The role of insulin-like growth factor 2 receptor-mediated homeobox gene expression in human placental apoptosis, and its implications in idiopathic fetal growth restriction

Lynda K Harris, Priyadarshini Pantham, Hannah EJ Yong, Anita Pratt, Anthony J Borg, Ian Crocker, Melissa Westwood, John Aplin, Bill Kalionis, Padma Murthi

Journal article | 2019 | Molecular Human Reproduction

Fetal growth restriction (FGR) is caused by poor placental development and function early in gestation. It is well known that plac..

Dysregulation of the placental renin-angiotensin system in human fetal growth restriction

Sarah J Delforce, Eugenie R Lumbers, Stacey J Ellery, Padma Murthi, Kirsty G Pringle

Journal article | 2019 | Reproduction

Placental creatine metabolism in cases of placental insufficiency and reduced fetal growth

Stacey J Ellery, Padma Murthi, Miranda L Davies-Tuck, Paul A Della Gatta, Anthony K May, Greg M Kowalski, Damien L Callahan, Clinton R Bruce, Nicole O Alers, Suzanne L Miller, Jan Jaap HM Erwich, Euan M Wallace, David W Walker, Hayley Dickinson, Rod J Snow

Journal article | 2019 | Molecular Human Reproduction

Creatine is a metabolite involved in cellular energy homeostasis. In this study, we examined placental creatine content, and expre..

PHARMACOLOGICAL AGONIST COMPOUND 43 ATTENUATE PLACENTAL INFLAMMATION-INDUCED DECREASE IN FORMYL PEPTIDE RECEPTOR-2 AND ENHANCES TROPHOBLAST AND ENDOTHELIAL FUNCTION IN VITRO: POTENTIAL THERAPEUTIC TARGET FOR INFLAMMATION INDUCED FETAL GROWTH RESTRICTION

Padma Murthi, Anthony Borg

Conference Proceedings | 2019 | Placenta

Iron Deposition Leads to Hyperphosphorylation of Tau and Disruption of Insulin Signaling

Wenbin Wan, Lan Cao, Bill Kalionis, Padma Murthi, Shijin Xia, Yangtai Guan

Journal article | 2019 | Frontiers in Neurology

The relationship between the placental serotonin pathway and fetal growth restriction

Suveena Ranzil, David W Walker, Anthony J Borg, Euan M Wallace, Peter R Ebeling, Padma Murthi

Journal article | 2019 | Biochimie

Sulforaphane improves endothelial function and reduces placental oxidative stress in vitro

Annie G Cox, Seshini Gurusinghe, Rahana Abd Rahman, Bryan Leaw, Siow T Chan, Joanne C Mockler, Padma Murthi, Sarah A Marshall, Rebecca Lim, Euan M Wallace

Journal article | 2019 | Pregnancy Hypertension

NLRP7 is increased in human idiopathic fetal growth restriction and plays a critical role in trophoblast differentiation

R Abi Nahed, D Reynaud, AJ Borg, W Traboulsi, A Wetzel, V Sapin, S Brouillet, MN Dieudonne, M Dakouane-Giudicelli, M Benharouga, P Murthi, Nadia Alfaidy

Journal article | 2019 | Journal of Molecular Medicine

Study of Human T21 Placenta Suggests a Potential Role of Mesenchymal Spondin-2 in Placental Vascular Development

Pascale Gerbaud, Padma Murthi, Jean Guibourdenche, Fabien Guimiot, Benoit Sarazin, Daniele Evain-Brion, Josette Badet, Guillaume Pidoux

Journal article | 2019 | Endocrinology

Imbalance between Placental Renin-Angiotensin Pathways Regulating Vasoconstriction and Vasodilation in Placentae from Pregnancies Complicated by Idiopathic Human Fetal Growth Restriction: Implications for Uteroplacental Blood Flow?

Sarah J Delforce, Eugenie R Lumbers, Stacey J Ellery, Padma Murthi, Kirsty G Pringle

Conference Proceedings | 2019 | REPRODUCTIVE SCIENCES

Vascular changes in fetal growth restriction: clinical relevance and future therapeutics

Arvind Sehgall, Padma Murthi, Jane E Dahlstrom

Journal article | 2019 | Journal of Perinatology

Decreased placental glypican expression is associated with human fetal growth restriction

T Gunatillake, A Chui, E Fitzpatrick, V Ignjatovic, P Monagle, J Whitelock, D Zanten, J Eijsink, A Borg, J Stevenson, SP Brennecke, JJHM Erwich, JM Said, P Murthi

Journal article | 2019 | Placenta

Low-dose aspirin treatment enhances the adhesion of preeclamptic decidual mesenchymal stem/stromal cells and reduces their production of pro-inflammatory cytokines

Ramin Khanabdali, Aida Shakouri-Motlagh, Sarah Wilkinson, Padma Murthi, Harry M Georgiou, Shaun P Brennecke, Bill Kalionis

Journal article | 2018 | Journal of Molecular Medicine

THE METABOLIC COMPONENTS OF SEROTONIN SYNTHESISING PATHWAY IS EXPRESSED ACROSS GESTATION AND ARE ALTERED IN HUMAN FETAL GROWTH RESTRICTION

Suveena Ranzil, Stacey Ellery, Jan Jaap Erwich, Jasper Eijsink, Dagmar van Zanten, Peter Ebeling, Euan Wallace, Padma Murthi

Conference Proceedings | 2018 | PLACENTA

Decidual ACVR2A regulates extravillous trophoblast functions of adhesion, proliferation, migration and invasion in vitro

Hannah EJ Yong, Padma Murthi, Bill Kalionis, Rosemary J Keogh, Shaun P Brennecke

Journal article | 2018 | Pregnancy Hypertension

Expression of Homeobox Gene HLX and its Downstream Target Genes are Altered in Placentae From Discordant Twin Pregnancies

Nicola Yuen, Shaun P Brennecke, Mark P Umstad, Hannah EJ Yong, Anthony J Borg, Gayathri Rajaraman, Bill Kalionis, Padma Murthi

Journal article | 2018 | Twin Research and Human Genetics

Formyl peptide receptor-2 is decreased in foetal growth restriction and contributes to placental dysfunction

Martha Lappas, Sharon McCracken, Kelly McKelvey, Ratana Lim, Joanna James, Claire T Roberts, Thierry Fournier, Nadia Alfaidy, Katie L Powell, Anthony J Borg, Jonathan M Morris, Bryan Leaw, Harmeet Singh, Peter R Ebeling, Euan M Wallace, Laura J Parry, Evdokia Dimitriadis, Padma Murthi

Journal article | 2018 | MHR: Basic science of reproductive medicine

Preeclampsia Methods and Protocols Preface

Cathy Vaillancourt, Padma Murthi

Book Chapter | 2018 | Methods in Molecular Biology

Treatment of preeclampsia with hydroxychloroquine: a review

Rahana Abd Rahman, Philip DeKoninck, Padma Murthi, Euan M Wallace

Journal article | 2018 | The Journal of Maternal-Fetal & Neonatal Medicine

Altered downstream target gene expression of the placental Vitamin D receptor in human idiopathic fetal growth restriction

Thy PH Nguyen, Hannah EJ Yong, Tejasvy Chollangi, Shaun P Brennecke, Susan J Fisher, Euan M Wallace, Peter R Ebeling, Padma Murthi

Journal article | 2018 | Cell Cycle

An Electrical Impedance-Based Assay to Examine Functions of Various Placental Cell Types In Vitro

Tejasvy Chollangi, Helene Clabault, Andree-Anne Hudon Thibeault, Hannah EJ Yong, Shagun Narula, Ellen Menkhorst, J Thomas Sanderson, Cathy Vaillancourt, Padma Murthi

Book Chapter | 2018 | Methods in Molecular Biology

Genetic Approaches in Preeclampsia

Hannah EJ Yong, Padma Murthi, Shaun P Brennecke, Eric K Moses

Book Chapter | 2018 | Methods in Molecular Biology

Ex Vivo Dual Perfusion of the Human Placenta: Disease Simulation, Therapeutic Pharmacokinetics and Analysis of Off-Target Effects

Paul Brownbill, Neil Sebire, Erin V McGillick, Stacey Ellery, Padma Murthi

Book Chapter | 2018 | Methods in Molecular Biology

Resveratrol mitigates trophoblast and endothelial dysfunction partly via activation of nuclear factor erythroid 2-related factor-2

Seshini Gurusinghe, Annie G Cox, Rahana Rahman, Siow T Chan, Ruth Muljadi, Harmeet Singh, Bryan Leaw, Joanne C Mockler, Sarah A Marshall, Padma Murthi, Rebecca Lim, Euan M Wallace

Journal article | 2017 | Placenta

IFPA meeting 2016 workshop report II: Placental imaging, placenta and development of other organs, sexual dimorphism in placental function and trophoblast cell lines

Jennifer Adibi, Graham J Burton, Vicki Clifton, Sally Collins, Antonio E Frias, Lobke Gierman, Peta Grigsby, Helen Jones, Cheryl Lee, Alina Maloyan, Udo R Markert, Diana M Morales-Prieto, Padma Murthi, Leslie Myatt, Jurgen Pollheimer, Victoria Roberts, Wendy Robinson, Carolyn Salafia, Matthias Schabel, Dinesh Shah, et al.

Journal article | 2017 | Placenta

Increased methylation and decreased expression of homeobox genes TLX1, HOXA10 and DLX5 in human placenta are associated with trophoblast differentiation

Boris Novakovic, Thierry Fournier, Lynda K Harris, Joanna James, Claire T Roberts, Hannah EJ Yong, Bill Kalionis, Daniele Evain-Brion, Peter R Ebeling, Euan M Wallace, Richard Saffery, Padma Murthi

Journal article | 2017 | Scientific Reports

Antiangiogenic effects of decorin restored by unfractionated, low molecular weight, and nonanticoagulant heparins

Amy KL Chui, Tilini N Gunatillake, Vera Ignjatovic, Paul T Monagle, Padma Murthi, Shaun P Brennecke, John M Whitelock, Joanne M Said

Journal article | 2017 | Blood Advances

Variable DAXX gene methylation is a common feature of placental trophoblast differentiation, preeclampsia, and response to hypoxia

Boris Novakovic, Daniele Evain-Brion, Padma Murthi, Thiery Fournier, Richard Saffery

Journal article | 2017 | The FASEB Journal

Expression of Biglycan in First Trimester Chorionic Villous Sampling Placental Samples and Altered Function in Telomerase-Immortalized Microvascular Endothelial Cells

Amy Chui, Tilini Gunatillake, Shaun P Brennecke, Vera Ignjatovic, Paul T Monagle, John M Whitelock, Dagmar E van Zanten, Jasper Eijsink, Yao Wang, James Deane, Anthony J Borg, Janet Stevenson, Jan Jaap Erwich, Joanne M Said, Padma Murthi

Journal article | 2017 | Arteriosclerosis, Thrombosis, and Vascular Biology

Creatine biosynthesis and transport by the term human placenta

Stacey J Ellery, Paul A Della Gatta, Clinton R Bruce, Greg M Kowalski, Miranda Davies-Tuck, Joanne C Mockler, Padma Murthi, David W Walker, Rod J Snow, Hayley Dickinson

Journal article | 2017 | Placenta

Altered placental tryptophan metabolic pathway in human fetal growth restriction

Padma Murthi, Euan M Wallace, David W Walker

Journal article | 2017 | Placenta

Maternal 25-hydroxyvitamin D is inversely correlated with foetal serotonin

Padma Murthi, Miranda Davies-Tuck, Martha Lappas, Harmeet Singh, Joanne Mockler, Rahana Rahman, Rebecca Lim, Bryan Leaw, James Doery, Euan M Wallace, Peter R Ebeling

Journal article | 2017 | Clinical Endocrinology

Placental Vitamin D-Binding Protein Expression in Human Idiopathic Fetal Growth Restriction

Alice F Wookey, Tejasvy Chollangi, Hannah EJ Yong, Bill Kalionis, Shaun P Brennecke, Padma Murthi, Harry M Georgiou

Journal article | 2017 | JOURNAL OF PREGNANCY

Low-Dose Acetylsalicylic Acid Treatment Modulates the Production of Cytokines and Improves Trophoblast Function in an in Vitro Model of Early-Onset Preeclampsia

Shanika Panagodage, Hannah EJ Yong, Fabricio Da Silva Costa, Anthony J Borg, Bill Kalionis, Shaun P Brennecke, Padma Murthi

Journal article | 2016 | The American Journal of Pathology

Endocan expression is increased in the placenta from obese women with gestational diabetes mellitus

Padma Murthi, Ramona Sarkis, Ratana Lim, Caitlyn Nguyen-Ngo, Anita Pratt, Stella Liong, Martha Lappas

Journal article | 2016 | PLACENTA

Homeobox gene TGIF-1 is increased in placental endothelial cells of human fetal growth restriction

Tilini Gunatillake, Hannah EJ Yong, Caroline E Dunk, Rosemary J Keogh, Anthony J Borg, Judith E Cartwright, Guy S Whitley, Padma Murthi

Journal article | 2016 | Reproduction

The effects of hydroxychloroquine on endothelial dysfunction

Rahana Rahman, Padma Murthi, Harmeet Singh, Seshini Gurusinghe, Joanne C Mockler, Rebecca Lim, Euan M Wallace

Journal article | 2016 | Pregnancy Hypertension: An International Journal of Women's Cardiovascular Health

Decorin expression is decreased in first trimester placental tissue from pregnancies with small for gestation age infants at birth

P Murthi, DE van Zanten, JJH Eijsink, AJ Borg, JL Stevenson, B Kalionis, AK Chui, JM Said, SP Brennecke, JJHM Emrich

Journal article | 2016 | Placenta

Sustained Endocrine Gland-Derived Vascular Endothelial Growth Factor Levels Beyond the First Trimester of Pregnancy Display Phenotypic and Functional Changes Associated With the Pathogenesis of Pregnancy-Induced Hypertension

Frederic Sergent, Pascale Hoffmann, Sophie Brouillet, Vanessa Garnier, Aude Salomon, Padma Murthi, Mohamed Benharouga, Jean-Jacques Feige, Nadia Alfaidy

Journal article | 2016 | Hypertension

TNF-R1 as a first trimester marker for prediction of pre-eclampsia

Sammya Bezerra Maia e Holanda Moura, Felicity Park, Padma Murthi, Wellington P Martins, Stefan C Kane, Paul Williams, Jonathan Hyett, Fabricio da Silva Costa

Journal article | 2016 | The Journal of Maternal-Fetal & Neonatal Medicine

EGb761 protects against A beta(1-42) oligomer-induced cell damage via endoplasmic reticulum stress activation andHsp70 protein expression increase in SH-SY5Y cells

Lumei Liu, Chunyan Zhang, Bill Kalionis, Wenbin Wan, Padma Murthi, Chuan Chen, Yaming Li, Shijin Xia

Journal article | 2016 | Experimental Gerontology

The role of mesenchymal stem cells in the functions and pathologies of the human placenta

GD Kusuma, P Murthi, B Kalionis

Book Chapter | 2016

Role of the Placental Vitamin D Receptor in Modulating Feto-Placental Growth in Fetal Growth Restriction and Preeclampsia-Affected Pregnancies

Padma Murthi, Hannah EJ Yong, Thy PH Ngyuen, Stacey Ellery, Harmeet Singh, Rahana Rahman, Hayley Dickinson, David W Walker, Miranda Davies-Tuck, Euan M Wallace, Peter R Ebeling

Journal article | 2016 | Frontiers in Physiology

Epithelial-mesenchymal transition during extravillous trophoblast differentiation

Jessica E Davies, Juergen Pollheimer, Hannah EJ Yong, Maria I Kokkinos, Bill Kalionis, Martin Knoefler, Padma Murthi

Journal article | 2016 | Cell Adhesion & Migration

Anti-angiogenic collagen fragment arresten is increased from 16 weeks' gestation in pre-eclamptic plasma

Hannah EJ Yong, Padma Murthi, May H Wong, Bill Kalionis, Shaun P Brennecke, Rosemary J Keogh

Journal article | 2015 | Placenta

Isolation and characterisation of a novel trophoblast side-population from first trimester placentae

JL James, DG Hurley, TKJB Gamage, T Zhang, R Vather, P Pantham, P Murthi, LW Chamley

Journal article | 2015 | REPRODUCTION

Effects of normal and high circulating concentrations of activin A on vascular endothelial cell functions and vasoactive factor production

Hannah EJ Yong, Padma Murthi, May H Wong, Bill Kalionis, Judith E Cartwright, Shaun P Brennecke, Rosemary J Keogh

Journal article | 2015 | Pregnancy Hypertension: An International Journal of Women's Cardiovascular Health

Placental vitamin D receptor expression is decreased in human idiopathic fetal growth restriction

TPH Nguyen, HEJ Yong, T Chollangi, AJ Borg, SP Brennecke, P Murthi

Journal article | 2015 | Journal of Molecular Medicine

Genome-Wide Transcriptome Directed Pathway Analysis of Maternal Pre-Eclampsia Susceptibility Genes

Hannah EJ Yong, Phillip E Melton, Matthew P Johnson, Katy A Freed, Bill Kalionis, Padma Murthi, Shaun P Brennecke, Rosemary J Keogh, Eric K Moses

Journal article | 2015 | PLOS ONE

Decreased STAT3 in human idiopathic fetal growth restriction contributes to trophoblast dysfunction

AJ Borg, HEJ Yong, M Lappas, SA Degrelle, RJ Keogh, F Da Silva-Costa, T Fournier, M Abumaree, JA Keelan, B Kalionis, P Murthi

Journal article | 2015 | REPRODUCTION

Placenta-derived angiogenic proteins and their contribution to the pathogenesis of preeclampsia

Anita Pratt, Fabricio Da Silva Costa, Anthony J Borg, Bill Kalionis, Rosemary Keogh, Padma Murthi

Journal article | 2015 | ANGIOGENESIS

An EG-VEGF-Dependent Decrease in Homeobox Gene NKX3.1 Contributes to Cytotrophoblast Dysfunction: A Possible Mechanism in Human Fetal Growth Restriction

Padma Murthi, Sophie Brouillet, Anita Pratt, Anthony Borg, Bill Kalionis, Frederic Goffin, Vassilis Tsatsaris, Carine Munaut, Jean-Jacques Feige, Mohamed Benharouga, Thierry Fournier, Nadia Alfaidy

Journal article | 2015 | MOLECULAR MEDICINE

Normal and Pathological Placental Angiogenesis

Nathalie Bardin, Padma Murthi, Nadia Alfaidy

Journal article | 2015 | BioMed Research International

A Novel Combination of Homeobox Genes Is Expressed in Mesenchymal Chorionic Stem/Stromal Cells in First Trimester and Term Pregnancies

Haiying Liu, Padma Murthi, Sharon Qin, Gina D Kusuma, Anthony J Borg, Martin Knoefler, Peter Haslinger, Ursula Manuelpillai, Mark D Pertile, Mohamed Abumaree, Bill Kalionis

Journal article | 2014 | Reproductive Sciences

Soluble factors derived from human amniotic epithelial cells suppress collagen production in human hepatic stellate cells

Alexander Hodge, Dinushka Lourensz, Vijesh Vaghjiani, Nguyen Huyen, Jorge Tchongue, Bo Wang, Padma Murthi, William Sievert, Ursula Manuelpillai

Journal article | 2014 | Cytotherapy

Altered decorin leads to disrupted endothelial cell function: A possible mechanism in the pathogenesis of fetal growth restriction?

A Chui, P Murthi, T Gunatillake, SP Brennecke, V Ignjatovic, PT Monagle, JM Whitelock, JM Said

Journal article | 2014 | Placenta

Analysis of homeobox gene action may reveal novel angiogenic pathways in normal placental vasculature and in clinical pregnancy disorders associated with abnormal placental angiogenesis

Padma Murthi, Mohamed Abumaree, Bill Kalionis

Journal article | 2014 | Frontiers in Pharmacology

Hepatocyte-Like Cells Derived from Human Amniotic Epithelial Cells Can Be Encapsulated Without Loss of Viability or Function In Vitro

Vijesh Vaghjiani, Vijayaganapathy Vaithilingam, Indah Saraswati, Adnan Sali, Padma Murthi, Bill Kalionis, Bernard E Tuch, Ursula Manuelpillai

Journal article | 2014 | Stem Cells and Development

Human amniotic epithelial cells suppress relapse of corticosteroid-remitted experimental autoimmune disease

Yu-Han Liu, James Chan, Vijesh Vaghjiani, Padma Murthi, Ursula Manuelpillai, Ban-Hock Toh

Journal article | 2014 | Cytotherapy

Increased decidual mRNA expression levels of candidate maternal preeclampsia susceptibility genes are associated with clinical severity

HEJ Yong, P Murthi, A Borg, B Kalionis, EK Moses, SP Brennecke, RJ Keogh

Journal article | 2014 | Placenta

Review: Placental homeobox genes and their role in regulating human fetal growth

P Murthi

Journal article | 2014 | PLACENTA

Homeobox gene transforming growth factor -induced factor-1 (TGIF-1) is a regulator of villous trophoblast differentiation and its expression is increased in human idiopathic fetal growth restriction

Niroshani A Pathirage, Melanie Cocquebert, Yoel Sadovsky, Mohamed Abumaree, Ursula Manuelpillai, Anthony Borg, Rosemary J Keogh, Shaun P Brennecke, Daniele Evain-Brion, Thierry Fournier, Bill Kalionis, Padma Murthi

Journal article | 2013 | MOLECULAR HUMAN REPRODUCTION

Downstream targets of the homeobox gene DLX3 are differentially expressed in the placentae of pregnancies affected by human idiopathic fetal growth restriction

Amy Chui, Bill Kalionis, Mohamed Abumaree, Melanie Cocquebert, Thierry Fournier, Daniele Evain-Brion, Shaun P Brennecke, Padma Murthi

Journal article | 2013 | MOLECULAR AND CELLULAR ENDOCRINOLOGY

Anti-Inflammatory Effects of Adult Stem Cells in Sustained Lung Injury: A Comparative Study

Yuben Moodley, Vijesh Vaghjiani, James Chan, Svetlana Baltic, Marisa Ryan, Jorge Tchongue, Chrishan S Samuel, Padma Murthi, Ornella Parolini, Ursula Manuelpillai

Journal article | 2013 | PLOS ONE

Control of extravillous trophoblast function by the eotaxins CCL11, CCL24 and CCL26

Simon E Chau, Padma Murthi, May H Wong, Guy StJ Whitley, Shaun P Brennecke, Rosemary J Keogh

Journal article | 2013 | Human Reproduction

Homeobox genes and down-stream transcription factor PPAR gamma in normal and pathological human placental development

P Murthi, B Kalionis, M Cocquebert, G Rajaraman, A Chui, RJ Keogh, D Evain-Brion, T Fournier

Journal article | 2013 | PLACENTA

IFPA Meeting 2012 Workshop Report III: Trophoblast deportation, gestational trophoblastic disease, placental insufficiency and fetal growth restriction, trophoblast over-invasion and accreta-related pathologies, placental thrombosis and fibrinolysis

A Al-Khan, JN Bulmer, F Chantraine, CP Chen, Q Chen, S Collins, T Cotechini, JS Fitzgerald, M He, O Holland, TH Hung, NP Illsley, K Ino, T Iwaki, N Kanayama, E Kaneki, H Katabuchi, Y Kobayashi, A Kondo, H Masuzaki, et al.

Journal article | 2013 | Placenta

EG-VEGF controls placental growth and survival in normal and pathological pregnancies: case of fetal growth restriction (FGR)

S Brouillet, P Murthi, P Hoffmann, A Salomon, F Sergent, P De Mazancourt, M Dakouane-Giudicelli, MN Dieudonne, P Rozenberg, D Vaiman, S Barbaux, M Benharouga, J-J Feige, N Alfaidy

Journal article | 2013 | Cellular and Molecular Life Sciences

Immunogenicity and Immunomodulatory Properties of Hepatocyte-like Cells Derived from Human Amniotic Epithelial Cells

Jing Yang Tee, Vijesh Vaghjiani, Yu Han Liu, Padma Murthi, James Chan, Ursula Manuelpillai

Journal article | 2013 | CURRENT STEM CELL RESEARCH & THERAPY

Decidua Parietalis-Derived Mesenchymal Stromal Cells Reside in a Vascular Niche Within the Choriodecidua

NM Castrechini, P Murthi, S Qin, GD Kusuma, L Wilton, M Abumaree, S Gronthos, A Zannettino, NM Gude, SP Brennecke, B Kalionis

Journal article | 2012 | Reproductive Sciences

Re: Regulation of epithelial-mesenchymal transition by homeobox gene DLX4 in JEG-3 trophoblast cells: a role in preeclampsia.

Padma Murthi, Bill Kalionis

Journal article | 2012 | Reproductive sciences (Thousand Oaks, Calif.)

Comparative expression of hCG beta-genes in human trophoblast from early and late first-trimester placentas

M Cocquebert, S Berndt, N Segond, J Guibourdenche, P Murthi, L Aldaz-Carroll, D Evain-Brion, T Fournier

Journal article | 2012 | American Journal of Physiology - Endocrinology and Metabolism

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Padma Murthi, Bill Kalionis

Journal article | 2012 | Reproductive Sciences

Placental CLIC3 is increased in fetal growth restriction and pre-eclampsia affected human pregnancies

P Murthi, JL Stevenson, TT Money, AJ Borg, SP Brennecke, NM Gude

Journal article | 2012 | Placenta

Human Amniotic Epithelial Cell Transplantation Induces Markers of Alternative Macrophage Activation and Reduces Established Hepatic Fibrosis

Ursula Manuelpillai, Dinushka Lourensz, Vijesh Vaghjiani, Jorge Tchongue, Derek Lacey, Jing-Yang Tee, Padma Murthi, James Chan, Alexander Hodge, William Sievert

Journal article | 2012 | PLOS ONE

Homeobox gene Distal-Less 3 is a regulator of villous cytotrophoblast differentiation and its expression is increased in human idiopathic foetal growth restriction

Amy Chui, Charmaine Tay, Melanie Cocquebert, Penelope Sheehan, Niroshani A Pathirage, Susan Donath, Thierry Fournier, Josette Badet, Daniele Evain-Brion, Shaun P Brennecke, Bill Kalionis, Padma Murthi

Journal article | 2012 | Journal of Molecular Medicine

Placental Syndecan Expression Is Altered in Human Idiopathic Fetal Growth Restriction

Amy Chui, Nurul Zainuddin, Gayathri Rajaraman, Padma Murthi, Shaun P Brennecke, Vera Ignjatovic, Paul T Monagle, Joanne M Said

Journal article | 2012 | American Journal of Pathology

IFPA Meeting 2011 workshop report II: Angiogenic signaling and regulation of fetal endothelial function; placental and fetal circulation and growth; spiral artery remodeling

JN Bulmer, GJ Burton, S Collins, T Cotechini, IP Crocker, BA Croy, S Cvitic, M Desforges, R Deshpande, M Gasperowicz, T Groten, G Haugen, U Hiden, AJ Host, M Jirkovska, T Kiserud, J Koenig, L Leach, P Murthi, R Pijnenborg, et al.

Journal article | 2012 | Placenta

Prevention of preeclampsia.

Sammya Bezerra Maia E Holanda Moura, Laudelino Marques Lopes, Padma Murthi, Fabricio da Silva Costa

Journal article | 2012 | Journal of Pregnancy

Preeclampsia (PE) affects around 2-5% of pregnant women. It is a major cause of maternal and perinatal morbidity and mortality. In..

The Role of Homeobox Genes in the Development of Placental Insufficiency

Padma Murthi, Bill Kalionis, Gayathri Rajaraman, Rosemary J Keogh, Fabricio Da Silva Costa

Journal article | 2012 | Fetal Diagnosis and Therapy

The Expression of Placental Proteoglycans in Pre-Eclampsia

A Chui, P Murthi, SP Brennecke, V Ignjatovic, PT Monagle, JM Said

Journal article | 2012 | GYNECOLOGIC AND OBSTETRIC INVESTIGATION

Mesenchymal Activin-A Overcomes Defective Human Trisomy 21 Trophoblast Fusion

Pascale Gerbaud, Guillaume Pidoux, Jean Guibourdenche, Niroshani Pathirage, Jean Marc Costa, Josette Badet, Jean-Louis Frendo, Padma Murthi, Daniele Evain-Brion

Journal article | 2011 | Endocrinology

Changes in Culture Expanded Human Amniotic Epithelial Cells: Implications for Potential Therapeutic Applications

Gita Pratama, Vijesh Vaghjiani, Jing Yang Tee, Yu Han Liu, James Chan, Charmaine Tan, Padma Murthi, Caroline Gargett, Ursula Manuelpillai

Journal article | 2011 | PLoS One

Early screening for preeclampsia.

Fabrício da Silva Costa, Padma Murthi, Rosemary Keogh, Nicole Woodrow

Journal article | 2011 | Revista Brasileira de Ginecologia e Obstetricia

Preeclampsia, which affects about 3 to 5% of pregnant women, is the most frequent medical complication in pregnancy and the most i..

Expression and localization of DLX3, PPARG and SP1 in bovine trophoblast during binucleated cell differentiation

SA Degrelle, P Murthi, D Evain-Brion, T Fournier, I Hue

Journal article | 2011 | Placenta

Homeobox gene Distal-less 3 (DLX3) is a regulator of villous cytotrophoblast differentiation

A Chui, DA Evseenko, SP Brennecke, JA Keelan, B Kalionis, P Murthi

Journal article | 2011 | Placenta

IFPA Meeting 2010 Workshop Report I: Immunology; Ion transport; Epigenetics; Vascular reactivity; Epitheliochorial placentation; Proteomics

C Abad, DF Antczak, J Carvalho, LW Chamley, Q Chen, S Daher, AE Damiano, V Dantzer, P Diaz, CE Dunk, E Daly, C Escudero, B Falcon, M Guillomot, YW Han, LK Harris, JP Huidobro-Toro, N Illsley, H Jammes, T Jansson, et al.

Journal article | 2011 | Placenta

Involvement of Gax Gene in Hypoxia-Induced Pulmonary Hypertension, Proliferation, and Apoptosis of Arterial Smooth Muscle Cells

Shijin Xia, Xiantao Tai, Yaoli Wang, Xiaojing An, Guisheng Qian, Jingcheng Dong, Xun Wang, Baokang Sha, Diane Wang, Padma Murthi, Bill Kalionis, Xiangdong Wang, Chunxue Bai

Journal article | 2011 | American Journal of Respiratory Cell and Molecular Biology

The role of placental homeobox genes in human fetal growth restriction.

Padma Murthi, Gayathri Rajaraman, Shaun Patrick Brennecke, Bill Kalionis

Journal article | 2011 | Journal of Pregnancy

Fetal growth restriction (FGR) is an adverse pregnancy outcome associated with significant perinatal and paediatric morbidity and ..

Homeobox Gene HLX Is a Regulator of HGF/c-met-Mediated Migration of Human Trophoblast-Derived Cell Lines

Gayathri Rajaraman, Padma Murthi, Shaun P Brennecke, Bill Kalionis

Journal article | 2010 | Biology of Reproduction