Padma Murthi

HIV in pregnancy: Mother-to-child transmission, pharmacotherapy, and toxicity

Lukas Cerveny, Padma Murthi, Frantisek Staud

Journal article  |  2021  |  BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE

An estimated 1.3 million pregnant women were living with HIV in 2018. HIV infection is associated with adverse pregnancy outcomes ..

Significance of the placental barrier in antenatal viral infections.

Hannah EJ Yong, Shiao-Yng Chan, Amlan Chakraborty, Gayathri Rajaraman, Sharon Ricardo, Mohamed Benharouga, Nadia Alfaidy, Frantisek Staud, Padma Murthi

Journal article  |  2021  |  Biochim Biophys Acta Mol Basis Dis

The placenta provides a significant physical and physiological barrier to prevent fetal infection during pregnancy. Nevertheless, ..

NLRP7 Promotes Choriocarcinoma Growth and Progression through the Establishment of an Immunosuppressive Microenvironment

Deborah Reynaud, Roland Abi Nahed, Nicolas Lemaitre, Pierre-Adrien Bolze, Wael Traboulsi, Frederic Sergent, Christophe Battail, Odile Filhol, Vincent Sapin, Houssine Boufettal, Pascale Hoffmann, Touria Aboussaouira, Padma Murthi, Rima Slim, Mohamed Benharouga, Nadia Alfaidy

Journal article  |  2021  |  CANCERS

The inflammatory gene NLRP7 is the major gene responsible for recurrent complete hydatidiform moles (CHM), an abnormal pregnancy t..

Placental serotonin systems in pregnancy metabolic complications associated with maternal obesity and gestational diabetes mellitus (Retraction of Vol 1866, art no 65391, 2020)

Padma Murthi, Cathy Vaillancourt

Journal article  |  2021  |  BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE

This article has been retracted: please see Elsevier Policy on Article Withdrawal (https://www.elsevier.com/about/our-business/pol..

Evidence-Based View of Safety and Effectiveness of Prokineticin Receptors Antagonists during Pregnancy

Deborah Reynaud, Frederic Sergent, Roland Abi Nahed, Wael Traboulsi, Constance Collet, Christel Marquette, Pascale Hoffmann, Gianfranco Balboni, Qun-Yong Zhou, Padma Murthi, Mohamed Benharouga, Nadia Alfaidy

Journal article  |  2021  |  BIOMEDICINES

Endocrine gland derived vascular endothelial growth factor (EG-VEGF) is a canonical member of the prokineticin (PROKs) family. It ..

Combining mesenchymal stem cells with serelaxin provides enhanced renoprotection against 1K/DOCA/salt-induced hypertension

Yifang Li, Matthew Shen, Dorota Ferens, Brad RS Broughton, Padma Murthi, Sheetal Saini, Robert E Widdop, Sharon D Ricardo, Anita A Pinar, Chrishan S Samuel

Journal article  |  2021  |  BRITISH JOURNAL OF PHARMACOLOGY

BACKGROUND AND PURPOSE: Fibrosis is a hallmark of chronic kidney disease (CKD) that significantly contributes to renal dysfunction..

The placenta is the villain or victim in the pathogenesis of pre-eclampsia: FOR: The placenta is the villain in the pathogenesis of preeclampsia

P Murthi, SP Brennecke

Journal article  |  2021  |  BJOG: an International Journal of Obstetrics and Gynaecology

Inflammasomes in the Pathophysiology of Maternal Obesity: Potential Therapeutic Targets to Reduce Long-Term Adverse Health Outcomes in the Mother and Offspring

Padma Murthi, Gayathri Rajaraman

Journal article  |  2021  |  CURRENT VASCULAR PHARMACOLOGY

Over the past 20 years, the prevalence of obesity has risen dramatically worldwide, with an increase in occurrence among women in ..

The Emerging Role of the Prokineticins and Homeobox Genes in the Vascularization of the Placenta: Physiological and Pathological Aspects

Nadia Alfaidy, Sophie Brouillet, Gayathri Rajaraman, Bill Kalionis, Pascale Hoffmann, Tiphaine Barjat, Mohamed Benharouga, Padma Murthi

Journal article  |  2020  |  FRONTIERS IN PHYSIOLOGY

Vasculogenesis and angiogenesis are key processes of placental development, which occur throughout pregnancy. Placental vasculogen..

Decidual mesenchymal stem/stromal cell-derived extracellular vesicles ameliorate endothelial cell proliferation, inflammation, and oxidative stress in a cell culture model of preeclampsia

Shixuan Zheng, Aiwu Shi, Sophia Hill, Claire Grant, Maria I Kokkinos, Padma Murthi, Harry M Georgiou, Shaun P Brennecke, Bill Kalionis

Journal article  |  2020  |  Pregnancy Hypertension

Oxidative stress and endothelial dysfunction contribute substantially to the pathogenesis of preeclampsia (PE). Decidual mesenchym..