Noel Cranswick

Impact of antibiotic allergy labels on patient outcomes in a tertiary paediatric hospital

Anthony C Catalano, Laure F Pittet, Sharon Choo, Ahuva Segal, David Stephens, Noel E Cranswick, Amanda Gwee

Journal article  |  2021  |  BRITISH JOURNAL OF CLINICAL PHARMACOLOGY

AIMS: Antibiotic allergies are reported in 5-15% of children. This study aimed to evaluate the impact of common β-lactam antibioti..

Population pharmacokinetics of ivermectin for the treatment of scabies in Indigenous Australian children

Amanda Gwee, Stephen Duffull, Xiao Zhu, Steven YC Tong, Noel Cranswick, Brett McWhinney, Jacobus Ungerer, Joshua Francis, Andrew C Steer

Journal article  |  2020  |  PLOS NEGLECTED TROPICAL DISEASES

Ivermectin is a broad-spectrum antiparasitic agent used for the treatment and control of neglected tropical diseases. In Australia..

A pilot randomised placebo-controlled trial of cannabidiol to reduce severe behavioural problems in children and adolescents with intellectual disability

Daryl Efron, Jeremy L Freeman, Noel Cranswick, Jonathan M Payne, Melissa Mulraney, Chidambaram Prakash, Katherine J Lee, Kaitlyn Taylor, Katrina Williams

Journal article  |  2020  |  BRITISH JOURNAL OF CLINICAL PHARMACOLOGY

AIMS: Severe behavioural problems (SBP) are a major contributor to morbidity in children with intellectual disability (ID). Medica..

A nationwide parent survey of antibiotic use in Australian children

Rebecca Anderson, Anthea Rhodes, Noel Cranswick, Marnie Downes, Jonathan O'Hara, Mary-Anne Measey, Amanda Gwee

Journal article  |  2020  |  JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY

BACKGROUND: Antimicrobial resistance is increasing globally, largely due to high rates of antibiotic use and misuse. Factors that ..

Does cannabidiol reduce severe behavioural problems in children with intellectual disability? Study protocol for a pilot single-site phase I/II randomised placebo controlled trial

Daryl Efron, Kaitlyn Taylor, Jonathan M Payne, Jeremy L Freeman, Noel Cranswick, Melissa Mulraney, Chidambaram Prakash, Katherine J Lee, Katrina Williams

Journal article  |  2020  |  BMJ Open

INTRODUCTION: Severe behavioural problems (SBPs) are a common contributor to morbidity and reduced quality of life in children wit..

Non-beta-Lactam Antibiotic Hypersensitivity Reactions

Lisa Grinlington, Sharon Choo, Noel Cranswick, Amanda Gwee

Journal article  |  2020  |  PEDIATRICS

OBJECTIVES: Antibiotics are among the most common prescriptions in children, and non-β-lactam antibiotics (NBLAs) account for almo..

Using high-resolution Twin-Ion Metabolite Extraction (HiTIME) mass spectrometry with stable isotope labelling to investigate the metabolism of valproic acid in vivo

Michael G Leeming, Noel Cranswick, Christine E Wright, James Ziogas, Terence J O'Brien, William A Donald, Richard AJ O'Hair

Journal article  |  2019  |  INTERNATIONAL JOURNAL OF MASS SPECTROMETRY

Valproic acid (VPA) is a medication that is widely used in the treatment of epilepsy and bipolar disorder, despite a known potenti..

Optimizing Mycophenolic Acid Exposure in Kidney Transplant Recipients: Time for Target Concentration Intervention

David K Metz, Nick Holford, Joshua Y Kausman, Amanda Walker, Noel Cranswick, Christine E Staatz, Katherine A Barraclough, Francesco Ierino

Journal article  |  2019  |  TRANSPLANTATION

The immunosuppressive agent mycophenolate is used extensively in kidney transplantation, yet dosing strategy applied varies marked..

A PILOT RANDOMIZED CONTROLLED TRIAL OF CANNABIDIOL TO REDUCE SEVERE BEHAVIORAL PROBLEMS IN CHILDREN AND ADOLESCENTS WITH INTELLECTUAL DISABILITY

Daryl Efron, Jeremy Freeman, Noel Cranswick, Jonathan Payne, Melissa Mulraney, Chidambaram Prakash, Katherine Lee, Kaitlyn Taylor, Katrina Williams

Conference Proceedings  |  2019  |  JOURNAL OF THE AMERICAN ACADEMY OF CHILD AND ADOLESCENT PSYCHIATRY

Vancomycin is commonly under-dosed in critically ill children and neonates

Natasha Sosnin, Nigel Curtis, Noel Cranswick, Roberto Chiletti, Amanda Gwee

Journal article  |  2019  |  BRITISH JOURNAL OF CLINICAL PHARMACOLOGY

AIMS: Vancomycin is frequently used in critically ill children in whom the drug pharmacokinetics are significantly altered as a re..