Mark Jenkins

Mendelian randomization of circulating polyunsaturated fatty acids and colorectal cancer risk.

Nikhil K Khankari, Barbara L Banbury, Maria C Borges, Philip Haycock, Demetrius Albanes, Volker Arndt, Sonja I Berndt, Stéphane Bézieau, Hermann Brenner, Peter T Campbell, Graham Casey, Andrew T Chan, Jenny Chang-Claude, David V Conti, Michelle Cotterchio, Dallas R English, Jane C Figueiredo, Graham G Giles, Edward L Giovannucci, Marc J Gunter, et al.

Journal article  |  2020  |  Cancer Epidemiology Biomarkers & Prevention

BACKGROUND: Results from epidemiologic studies examining polyunsaturated fatty acids (PUFAs) and colorectal cancer (CRC) risk are ..

Utility of the methylated SEPT9 test for the early detection of colorectal cancer: a systematic review and meta-analysis of diagnostic test accuracy

Rohit Hariharan, Mark Jenkins

Journal article  |  2020  |  BMJ Open Gastroenterology

BackgroundCirculating tumour DNA from colorectal cancer (CRC) is a biomarker for early detection of the disease and therefore pote..

Physical activity and risks of breast and colorectal cancer: a Mendelian randomisation analysis.

Nikos Papadimitriou, Niki Dimou, Konstantinos K Tsilidis, Barbara Banbury, Richard M Martin, Sarah J Lewis, Nabila Kazmi, Timothy M Robinson, Demetrius Albanes, Krasimira Aleksandrova, Sonja I Berndt, D Timothy Bishop, Hermann Brenner, Daniel D Buchanan, Bas Bueno-de-Mesquita, Peter T Campbell, Sergi Castellví-Bel, Andrew T Chan, Jenny Chang-Claude, Merete Ellingjord-Dale, et al.

Journal article  |  2020  |  Nature Communications

Physical activity has been associated with lower risks of breast and colorectal cancer in epidemiological studies; however, it is ..

DNA repair and cancer in colon and rectum: Novel players in genetic susceptibility

Barbara Pardini, Alda Corrado, Elisa Paolicchi, Giovanni Cugliari, Sonja Berndt, Stephane Bezieau, Stephanie A Bien, Hermann Brenner, Bette J Caan, Peter T Campbell, Graham Casey, Andrew T Chan, Jenny Chang-Claude, Michelle Cotterchio, Manish Gala, Steven J Gallinger, Robert W Haile, Tabitha A Harrison, Richard B Hayes, Michael Hoffmeister, et al.

Journal article  |  2020  |  International Journal of Cancer

Interindividual differences in DNA repair systems may play a role in modulating the individual risk of developing colorectal cance..

A new comprehensive colorectal cancer risk prediction model incorporating family history, personal characteristics, and environmental factors.

Yingye Zheng, Xinwei Hua, Aung K Win, Robert J MacInnis, Steven Gallinger, Loic Le Marchand, Noralane M Lindor, John A Baron, John L Hopper, James G Dowty, Antonis C Antoniou, Jiayin Zheng, Mark A Jenkins, Polly A Newcomb

Journal article  |  2020  |  Cancer Epidemiology Biomarkers & Prevention

BACKGROUND: Reducing colorectal cancer (CRC) incidence and mortality through early detection would improve efficacy if targeted. W..

Fine-mapping of 150 breast cancer risk regions identifies 191 likely target genes

Laura Fachal, Hugues Aschard, Jonathan Beesley, Daniel R Barnes, Jamie Allen, Siddhartha Kar, Karen A Pooley, Joe Dennis, Kyriaki Michailidou, Constance Turman, Penny Soucy, Audrey Lemacon, Michael Lush, Jonathan P Tyrer, Maya Ghoussaini, Mahdi Moradi Marjaneh, Xia Jiang, Simona Agata, Kristiina Aittomaki, M Rosario Alonso, et al.

Journal article  |  2020  |  Nature Genetics

Genome-wide association studies have identified breast cancer risk variants in over 150 genomic regions, but the mechanisms underl..

Cost-Effectiveness of Personalized Screening for Colorectal Cancer Based on Polygenic Risk and Family History.

Dayna R Cenin, Steffie K Naber, Anne C de Weerdt, Mark A Jenkins, David B Preen, Hooi C Ee, Peter C O'Leary, Iris Lansdorp-Vogelaar

Journal article  |  2020  |  Cancer Epidemiology Biomarkers & Prevention

BACKGROUND: There is growing evidence for personalizing colorectal cancer screening based on risk factors. We compared the cost-ef..

Childhood pneumonia, pleurisy and lung function: a cohort study from the first to sixth decade of life

Jennifer L Perret, Caroline J Lodge, Adrian J Lowe, David P Johns, Bruce R Thompson, Dinh S Bui, Lyle C Gurrin, Melanie C Matheson, Christine F McDonald, Richard Wood-Baker, Cecilie Svanes, Paul S Thomas, Graham G Giles, Anne B Chang, Michael J Abramson, E Haydn Walters, Shyamali C Dharmage, Heather Gibson, Bryan Gandevia, Harold Silverstone, et al.

Journal article  |  2020  |  Thorax

INTRODUCTION: Adult spirometry following community-acquired childhood pneumonia has variably been reported as showing obstructive ..

Cancer risks by gene, age, and gender in 6350 carriers of pathogenic mismatch repair variants: findings from the Prospective Lynch Syndrome Database

Mev Dominguez-Valentin, Julian R Sampson, Toni T Seppala, Sanne W ten Broeke, John-Paul Plazzer, Sigve Nakken, Christoph Engel, Stefan Aretz, Mark A Jenkins, Lone Sunde, Inge Bernstein, Gabriel Capella, Francesc Balaguer, Huw Thomas, D Gareth Evans, John Burn, Marc Greenblatt, Eivind Hovig, Wouter H de Vos Tot Nederveen Cappel, Rolf H Sijmons, et al.

Journal article  |  2020  |  Genetics in Medicine

PURPOSE: Pathogenic variants affecting MLH1, MSH2, MSH6, and PMS2 cause Lynch syndrome and result in different but imprecisely kno..

Modifiable pathways for colorectal cancer: a mendelian randomisation analysis

Alex J Cornish, Philip J Law, Maria Timofeeva, Kimmo Palin, Susan M Farrington, Claire Palles, Mark A Jenkins, Graham Casey, Hermann Brenner, Jenny Chang-Claude, Michael Hoffmeister, Iva Kirac, Tim Maughan, Stefanie Brezina, Andrea Gsur, Jeremy P Cheadle, Lauri A Aaltonen, Ian Tomlinson, Malcolm G Dunlop, Richard S Houlston

Journal article  |  2020  |  The Lancet Gastroenterology & Hepatology

BACKGROUND: Epidemiological studies have linked lifestyle, cardiometabolic, reproductive, developmental, and inflammatory factors ..

Circulating Levels of Insulin-like Growth Factor 1 and Insulin-like Growth Factor Binding Protein 3 Associate With Risk of Colorectal Cancer Based on Serologic and Mendelian Randomization Analyses.

Neil Murphy, Robert Carreras-Torres, Mingyang Song, Andrew T Chan, Richard M Martin, Nikos Papadimitriou, Niki Dimou, Konstantinos K Tsilidis, Barbara Banbury, Kathryn E Bradbury, Jelena Besevic, Sabina Rinaldi, Elio Riboli, Amanda J Cross, Ruth C Travis, Claudia Agnoli, Demetrius Albanes, Sonja I Berndt, Stéphane Bézieau, D Timothy Bishop, et al.

Journal article  |  2019  |  Gastroenterology

BACKGROUND AIMS: Human studies examining associations between circulating levels of insulin-like growth factor 1 (IGF1) and insuli..

Cumulative Burden of Colorectal Cancer-Associated Genetic Variants is More Strongly Associated With Early-onset vs Late-onset Cancer.

Alexi N Archambault, Yu-Ru Su, Jihyoun Jeon, Minta Thomas, Yi Lin, David V Conti, Aung Ko Win, Lori C Sakoda, Iris Lansdorp-Vogelaar, Elisabeth Fp Peterse, Ann G Zauber, David Duggan, Andreana N Holowatyj, Jeroen R Huyghe, Hermann Brenner, Michelle Cotterchio, Stéphane Bézieau, Stephanie L Schmit, Christopher K Edlund, Melissa C Southey, et al.

Journal article  |  2019  |  Gastroenterology

BACKGROUND & AIMS: Early-onset colorectal cancer (CRC, in persons younger than 50 years old) is increasing in incidence; yet, in t..

Systematic meta-analyses, field synopsis and global assessment of the evidence of genetic association studies in colorectal cancer.

Zahra Montazeri, Xue Li, Christine Nyiraneza, Xiangyu Ma, Maria Timofeeva, Victoria Svinti, Xiangrui Meng, Yazhou He, Yacong Bo, Samuel Morgan, Sergi Castellví-Bel, Clara Ruiz-Ponte, Ceres Fernández-Rozadilla, Ángel Carracedo, Antoni Castells, Timothy Bishop, Daniel Buchanan, Mark A Jenkins, Temitope O Keku, Annika Lindblom, et al.

Journal article  |  2019  |  Gut

OBJECTIVE: To provide an understanding of the role of common genetic variations in colorectal cancer (CRC) risk, we report an upda..

Development and validation of a targeted gene sequencing panel for application to disparate cancers.

Mark J McCabe, Marie-Emilie A Gauthier, Chia-Ling Chan, Tanya J Thompson, Sunita MC De Sousa, Clare Puttick, John P Grady, Velimir Gayevskiy, Jiang Tao, Kevin Ying, Arcadi Cipponi, Niantao Deng, Alex Swarbrick, Melissa L Thomas, Reginald V Lord, Amber L Johns, Maija Kohonen-Corish, Sandra A O'Toole, Jonathan Clark, Simon A Mueller, et al.

Journal article  |  2019  |  Scientific Reports

Next generation sequencing has revolutionised genomic studies of cancer, having facilitated the development of precision oncology ..

Interval breast cancer risk associations with breast density, family history and breast tissue aging

Tuong L Nguyen, Shuai Li, Gillian S Dite, Ye K Aung, Christopher F Evans, Ho N Trinh, Laura Baglietto, Jennifer Stone, Yun-Mi Song, Joohon Sung, Dallas R English, Mark A Jenkins, Pierre-Antoine Dugue, Roger L Milne, Melissa C Southey, Graham G Giles, Malcolm C Pike, John L Hopper

Journal article  |  2019  |  International Journal of Cancer

Interval breast cancers (those diagnosed between recommended mammography screens) generally have poorer outcomes and are more comm..

Type 2 diabetes mellitus, blood cholesterol, triglyceride and colorectal cancer risk in Lynch syndrome

S Ghazaleh Dashti, Wing Yan Li, Daniel D Buchanan, Mark Clendenning, Christophe Rosty, Ingrid M Winship, Finlay A Macrae, Graham G Giles, Sheetal Hardikar, Xinwei Hua, Stephen N Thibodeau, Jane C Figueiredo, Graham Casey, Robert W Haile, Steven Gallinger, Loic Le Marchand, Polly A Newcomb, John D Potter, Noralane M Lindor, John L Hopper, et al.

Journal article  |  2019  |  British Journal of Cancer

BACKGROUND: Type 2 diabetes mellitus and high total cholesterol and triglycerides are known to be associated with increased colore..

The FANCM:p.Arg658* truncating variant is associated with risk of triple-negative breast cancer

Gisella Figlioli, Massimo Bogliolo, Irene Catucci, Laura Caleca, Sandra Viz Lasheras, Roser Pujol, Johanna Kiiski, Taru A Muranen, Daniel R Barnes, Joe Dennis, Kyriaki Michailidou, Manjeet K Bolla, Goska Leslie, Cora M Aalfs, Muriel A Adank, Julian Adlard, Simona Agata, Karen Cadoo, Bjarni A Agnarsson, Thomas Ahearn, et al.

Journal article  |  2019  |  npj Breast Cancer

Breast cancer is a common disease partially caused by genetic risk factors. Germline pathogenic variants in DNA repair genes BRCA1..

Associations of pigmentary and naevus phenotype with melanoma risk in two populations with comparable ancestry but contrasting levels of ambient sun exposure

AE Cust, M Drummond, DT Bishop, L Azizi, H Schmid, MA Jenkins, JL Hopper, BK Armstrong, JF Aitken, RF Kefford, GG Giles, F Demenais, AM Goldstein, JH Barrett, PA Kanetsky, DE Elder, GJ Mann, JA Newton-Bishop

Journal article  |  2019  |  Journal of the European Academy of Dermatology and Venereology

BACKGROUND: People at high risk of developing melanoma are usually identified by pigmentary and naevus phenotypes. OBJECTIVE: We e..

Ability of known susceptibility SNPs to predict colorectal cancer risk for persons with and without a family history.

Mark A Jenkins, Aung K Win, James G Dowty, Robert J MacInnis, Enes Makalic, Daniel F Schmidt, Gillian S Dite, Mirosl Kapuscinski, Mark Clendenning, Christophe Rosty, Ingrid M Winship, Jon D Emery, Sibel Saya, Finlay A Macrae, Dennis J Ahnen, David Duggan, Jane C Figueiredo, Noralane M Lindor, Robert W Haile, John D Potter, et al.

Journal article  |  2019  |  Familial Cancer

Before SNP-based risk can be incorporated in colorectal cancer (CRC) screening, the ability of these SNPs to estimate CRC risk for..

Development and external validation study of a melanoma risk prediction model incorporating clinically assessed naevi and solar lentigines

K Vuong, BK Armstrong, M Drummond, JL Hopper, JH Barrett, JR Davies, DT Bishop, J Newton-Bishop, JF Aitken, GG Giles, H Schmid, MA Jenkins, GJ Mann, K McGeechan, AE Cust

Journal article  |  2019  |  British Journal of Dermatology

Smoking is associated with risks of molecular subtypes of colorectal cancer

Xiaoliang Wang, Efrat Amitay, Barbara L Banbury, Hermann Brenner, Daniel D Buchanan, Peter T Campbell, Jenny Chang-Claude, Steven J Gallinger, Graham G Giles, Tabitha A Harrison, John L Hopper, Mark A Jenkins, Yi Lin, Reiko Nishihara, Polly A Newcomb, Shuji Ogino, Lori C Sakoda, Robert E Schoen, Martha L Slattery, Steven N Thibodeau, et al.

Conference Proceedings  |  2019  |  Epidemiology

Risks of Colorectal Cancer and Cancer-Related Mortality in Familial Colorectal Cancer Type X and Lynch Syndrome Families

Yun-Hee Choi, Lajmi Lakhal-Chaieb, Agnieszka Krol, Bing Yu, Daniel Buchanan, Dennis Ahnen, Loic Le Marchand, Polly A Newcomb, Aung Ko Win, Mark Jenkins, Noralane M Lindor, Laurent Briollais

Journal article  |  2019  |  JNCI: Journal of the National Cancer Institute

Background: The risk of cancers is well characterized in Lynch syndrome (LS) families but has been less studied in familial colore..

Cancer screening in Australia: future directions in melanoma, Lynch syndrome, and liver, lung and prostate cancers

Marianne F Webe, Henry M Marshall, Nico E Rankin, Stephen Duffy, Kwun M Fong, Kate Dunlop, Lauren Humphreys, Amelia K Smit, Anne E Cust, Natalie Taylor, Gillian Mitchell, Yoon-Jung Kang, Kathy Tucker, Mark Jenkins, Finlay Macrae, Ian Lockart, Mark Danta, Bruce K Armstrong, Megan Howe

Journal article  |  2019  |  Public Health Research & Practice

Genetic variant predictors of gene expression provide new insight into risk of colorectal cancer (vol 138, pg 307, 2019)

Stephanie A Bien, Yu-Ru Su, David V Conti, Tabitha A Harrison, Conghui Qu, Xingyi Guo, Yingchang Lu, Demetrius Albanes, Paul L Auer, Barbara L Banbury, Sonja I Berndt, Stephane Bezieau, Hermann Brenner, Daniel D Buchanan, Bette J Caan, Peter T Campbell, Christopher S Carlson, Andrew T Chan, Jenny Chang-Claude, Sai Chen, et al.

Journal article  |  2019  |  Human Genetics

Tumor mutational signatures in sebaceous skin lesions from individuals with Lynch syndrome

Peter Georgeson, Michael D Walsh, Mark Clendenning, Simin Daneshvar, Bernard J Pope, Khalid Mahmood, Jihoon E Joo, Harindra Jayasekara, Mark A Jenkins, Ingrid M Winship, Daniel D Buchanan

Journal article  |  2019  |  Molecular Genetics & Genomic Medicine

Identification of circulating protein biomarkers for colorectal cancer risk: A genetic instrument analysis

Xiang Shu, Xiao-ou Shu, Jirong Long, Qiuyin Cai, Conghui Qu, Stephanie L Schmit, Chenxu Qu, Sonja I Berndt, Peter T Campbell, Andrew T Chan, Graham G Giles, Andrea Gsur, Michael Hoffmeister, Mark A Jenkins, Sanford D Markowitz, Li Li, Gad Rennert, Kenneth Offit, David Conti, Annika Lindblom, et al.

Conference Proceedings  |  2019  |  Epidemiology

Global trends in colorectal cancer mortality: projections to the year 2035

Marzieh Araghi, Isabelle Soerjomataram, Mark Jenkins, James Brierley, Eva Morris, Freddie Bray, Melina Arnold

Journal article  |  2019  |  International Journal of Cancer

Loss of Independence After Operative Management of Femoral Neck Fractures

Emil H Schemitsch, Sheila Sprague, Martin J Heetveld, Sofia Bzovsky, Diane Heels-Ansdell, Qi Zhou, Marc Swiontkowski, Mohit Bhandari, M Bhandari, M Swiontkowski, PJ Devereaux, Gordon Guyatt, MJ Heetveld, Kyle Jeray, Susan Liew, Martin Richardson, EH Schemitsch, Lehana Thabane, Paul Tornetta, Stephen D Walter, et al.

Journal article  |  2019  |  Journal of Orthopaedic Trauma

Mendelian randomization analysis of C-reactive protein on colorectal cancer risk

Xiaoliang Wang, James Y Dai, Demetrius Albanes, Volker Arndt, Sonja I Berndt, Stephane Bezieau, Hermann Brenner, Daniel D Buchanan, Katja Butterbach, Bette Caan, Graham Casey, Peter T Campbell, Andrew T Chan, Zhengyi Chen, Jenny Chang-Claude, Michelle Cotterchio, Douglas F Easton, Graham G Giles, Edward Giovannucci, William M Grady, et al.

Journal article  |  2019  |  International Journal of Epidemiology

Background: Chronic inflammation is a risk factor for colorectal cancer (CRC). Circulating C-reactive protein (CRP) is also modera..

Differences in MSI phenotype between cancer types using a new PCR-based pan-cancer biomarker panel.

Jeff Bacher, Eshwar Udho, Doug Storts, Richard Halberg, Steven Gallinger, Mark A Jenkins, Noralane M Lindor

Conference Proceedings  |  2019  |  Journal of Clinical Oncology

Association analyses identify 31 new risk loci for colorectal cancer susceptibility

Philip J Law, Maria Timofeeva, Ceres Fernandez-Rozadilla, Aria Timofeeva, Peter Broderick, James Studd, Juan Fernandez-Tajes, Susan Farrington, Victoria Svinti, Claire Palles, Giulia Orlando, Amit Sud, Amy Holroyd, Steven Penegar, Evropi Theodoratou, Peter Vaughan-Shaw, Harry Campbell, Lina Zgaga, Caroline Hayward, Archie Campbell, et al.

Journal article  |  2019  |  Nature Communications

Meeting report from the joint IARC-NCI international cancer seminar series: a focus on colorectal cancer

MJ Gunter, S Alhomoud, M Arnold, H Brenner, J Burn, G Casey, AT Chan, AJ Cross, E Giovannucci, R Hoover, R Houlston, M Jenkins, P Laurent-Puig, U Peters, D Ransohoff, E Riboli, R Sinha, ZK Stadler, P Brennan, SJ Chanock

Journal article  |  2019  |  Annals of Oncology

Assessing the ProMCol classifier as a prognostic marker for non-metastatic colorectal cancer within the Melbourne Collaborative Cohort Study

Jihoon E Joo, Harindra Jayasekara, Ee Ming Wong, Mark Clendenning, Christophe Rosty, Ingrid M Winship, Mark A Jenkins, John L Hopper, Dallas R English, Roger L Milne, Graham G Giles, Melissa C Southey, Daniel D Buchanan

Journal article  |  2019  |  Gut

Meeting report from the joint IARC-NCI international cancer seminar series: a focus on colorectal cancer.

MJ Gunter, S Alhomoud, M Arnold, H Brenner, J Burn, G Casey, AT Chan, AJ Cross, E Giovannucci, R Hoover, R Houlston, M Jenkins, P Laurent-Puig, U Peters, D Ransohoff, E Riboli, R Sinha, ZK Stadler, P Brennan, SJ Chanock

Journal article  |  2019  |  Annals of oncology : official journal of the European Society for Medical Oncology

Despite significant progress in our understanding of the etiology, biology and genetics of colorectal cancer, as well as important..

Large-Scale Genome-Wide Association Study of East Asians Identifies Loci Associated With Risk for Colorectal Cancer

Yingchang Lu, Sun-Seog Kweon, Chizu Tanikawa, Wei-Hua Jia, Yong-Bing Xiang, Qiuyin Cai, Chenjie Zeng, Stephanie L Schmit, Aesun Shin, Keitaro Matsuo, Sun Ha Jee, Dong-Hyun Kim, Jeongseon Kim, Wanqing Wen, Jiajun Shi, Xingyi Guo, Bingshan Li, Nan Wang, Ben Zhang, Xinxiang Li, et al.

Journal article  |  2019  |  Gastroenterology

Genetic variant predictors of gene expression provide new insight into risk of colorectal cancer

Stephanie A Bien, Yu-Ru Su, David V Conti, Tabitha A Harrison, Conghui Qu, Xingyi Guo, Yingchang Lu, Demetrius Albanes, Paul L Auer, Barbara L Banbury, Sonja I Berndt, Stephane Bezieau, Hermann Brenner, Daniel D Buchanan, Bette J Caan, Peter T Campbell, Christopher S Carlson, Andrew T Chan, Jenny Chang-Claude, Sai Chen, et al.

Journal article  |  2019  |  Human Genetics

Cancer Risks for PMS2-Associated Lynch Syndrome (vol 29, pg 2961, 2018)

Sanne W ten Broeke, Heleen M van der Klift, Carli MJ Tops, Stefan Aretz, Inge Bernstein, Daniel D Buchanan, Albert de la Chapelle, Gabriel Capella, Mark Clendenning, Christoph Engel, Steven Gallinger, Encarna Gomez Garcia, Jane C Figueiredo, Robert Haile, Heather L Hampel, Liselotte van Hest, John L Hopper, Nicoline Hoogerbrugge, Magnus von Knebel Doeberitz, Loic Le Marchand, et al.

Journal article  |  2019  |  Journal of Clinical Oncology

Early-life exposure to sibling modifies the relationship between CD14 polymorphisms and allergic sensitization

Melisa YZ Lau, Shyamali C Dharmage, John A Burgess, Aung K Win, Adrian J Lowe, Caroline J Lodge, Jennifer Perret, Jennie Hui, Paul S Thomas, Graham Giles, Bruce R Thompson, Michael J Abramson, E Haydn Walters, Melanie C Matheson, Katrina J Allen, Geza Benke, James G Dowty, Bircan Erbas, Iain H Feather, Peter A Frith, et al.

Journal article  |  2019  |  Clinical & Experimental Allergy

Novel Common Genetic Susceptibility Loci for Colorectal Cancer

Stephanie L Schmit, Christopher K Edlund, Fredrick R Schumacher, Jian Gong, Tabitha A Harrison, Jeroen R Huyghe, Chenxu Qu, Marilena Melas, David J Van den Berg, Hansong Wang, Stephanie Tring, Sarah J Plummer, Demetrius Albanes, M Henar Alonso, Christopher I Amos, Kristen Anton, Aaron K Aragaki, Volker Arndt, Elizabeth L Barry, Sonja I Berndt, et al.

Journal article  |  2019  |  JNCI: Journal of the National Cancer Institute

Shared heritability and functional enrichment across six solid cancers

Xia Jiang, Hilary K Finucane, Fredrick R Schumacher, Stephanie L Schmit, Jonathan P Tyrer, Younghun Han, Kyriaki Michailidou, Corina Lesseur, Karoline B Kuchenbaecker, Joe Dennis, David V Conti, Graham Casey, Mia M Gaudet, Jeroen R Huyghe, Demetrius Albanes, Melinda C Aldrich, Angeline S Andrew, Irene L Andrulis, Hoda Anton-Culver, Antonis C Antoniou, et al.

Journal article  |  2019  |  Nature Communications

Polygenic Risk Scores for Prediction of Breast Cancer and Breast Cancer Subtypes

Nasim Mavaddat, Kyriaki Michailidou, Joe Dennis, Michael Lush, Laura Fachal, Andrew Lee, Jonathan P Tyrer, Ting-Huei Chen, Qin Wang, Manjeet K Bolla, Xin Yang, Muriel A Adank, Thomas Ahearn, Kristiina Aittomaki, Jamie Allen, Irene L Andrulis, Hoda Anton-Culver, Natalia N Antonenkova, Volker Arndt, Kristan J Aronson, et al.

Journal article  |  2019  |  The American Journal of Human Genetics

Trends in Colon and Rectal Cancer Incidence in Australia from 1982 to 2014: Analysis of Data on Over 375,000 Cases

Eleonora Feletto, Xue Qin Yu, Jie-Bin Lew, D James B St John, Mark A Jenkins, Finlay A Macrae, Suzanne E Mahady, Karen Canfell

Journal article  |  2019  |  Cancer Epidemiology Biomarkers & Prevention

Discovery of common and rare genetic risk variants for colorectal cancer

Jeroen R Huyghe, Stephanie A Bien, Tabitha A Harrison, Hyun Min Kang, Sai Chen, Stephanie L Schmit, David V Conti, Conghui Qu, Jihyoun Jeon, Christopher K Edlund, Peyton Greenside, Michael Wainberg, Fredrick R Schumacher, Joshua D Smith, David M Levine, Sarah C Nelson, Nasa A Sinnott-Armstrong, Demetrius Albanes, M Henar Alonso, Kristin Anderson, et al.

Journal article  |  2019  |  Nature Genetics

Assessment of a European Bladder Cancer Predictive Model for Non-Muscle Invasive Bladder Cancer in an Australian Cohort

Matthew Alberto, Stephanie Demkiw, Jeremy Goad, Mark Jenkins, Genevieve Duggan, Tyler Mow, Lih-Ming Wong

Journal article  |  2019  |  Bladder Cancer

Predicting interval and screen-detected breast cancers from mammographic density defined by different brightness thresholds

Tuong L Nguyen, Ye K Aung, Shuai Li, Ho Trinh Nhut, Christopher F Evans, Laura Baglietto, Kavitha Krishnan, Gillian S Dite, Jennifer Stone, Dallas R English, Yun-Mi Song, Joohon Sung, Mark A Jenkins, Melissa C Southey, Graham G Giles, John L Hopper

Journal article  |  2018  |  Breast Cancer Research

Benefits, Harms, and Cost-Effectiveness of Potential Age Extensions to the National Bowel Cancer Screening Program in Australia

Jie-Bin Lew, D James B St John, Finlay A Macrae, Jon D Emery, Hooi C Ee, Mark A Jenkins, Emily He, Paul Grogan, Michael Caruana, Marjolein JE Greuter, Veerle MH Coupe, Karen Canfell

Journal article  |  2018  |  Cancer Epidemiology Biomarkers & Prevention

Diagnostics for Pleiotropy in Mendelian Randomization Studies: Global and Individual Tests for Direct Effects

James Y Dai, Ulrike Peters, Xiaoyu Wang, Jonathan Kocarnik, Jenny Chang-Claude, Martha L Slattery, Andrew Chan, Mathieu Lemire, Sonja I Berndt, Graham Casey, Mingyang Song, Mark A Jenkins, Hermann Brenner, Aaron P Thrift, Emily White, Li Hsu

Journal article  |  2018  |  American Journal of Epidemiology

Revised Australian national guidelines for colorectal cancer screening: family history

Mark A Jenkins, Driss Ait Ouakrim, Alex Boussioutas, John L Hopper, Hooi C Ee, Jon D Emery, Finlay A Macrae, Albert Chetcuti, Laura Wuellner, D James B St John

Journal article  |  2018  |  Medical Journal of Australia

Physical activity and the risk of colorectal cancer in Lynch syndrome

S Ghazaleh Dashti, Aung Ko Win, Sheetal S Hardikar, Stephen E Glombicki, Sheila Mallenahalli, Selvi Thirumurthi, Susan K Peterson, Y Nancy You, Daniel D Buchanan, Jane C Figueiredo, Peter T Campbell, Steven Gallinger, Polly A Newcomb, John D Potter, Noralane M Lindor, Loic Le Marchand, Robert W Haile, John L Hopper, Mark A Jenkins, Karen M Basen-Engquist, et al.

Journal article  |  2018  |  International Journal of Cancer

Can genetic risk profiling aid risk categorisation for colorectal cancer?

Mark Jenkins

Conference Proceedings  |  2018  |  ASIA-PACIFIC JOURNAL OF CLINICAL ONCOLOGY

Epidemiology of lynch syndrome

Mark Jenkins

Conference Proceedings  |  2018  |  ASIA-PACIFIC JOURNAL OF CLINICAL ONCOLOGY

Cancer Risks for PMS2-Associated Lynch Syndrome

Sanne W ten Broeke, Heleen M van der Klift, Carli MJ Tops, Stefan Aretz, Inge Bernstein, Daniel D Buchanan, Albert de la Chapelle, Gabriel Capella, Mark Clendenning, Christoph Engel, Steven Gallinger, Encarna Gomez Garcia, Jane C Figueiredo, Robert Haile, Heather L Hampel, John L Hopper, Nicoline Hoogerbrugge, Magnus von Knebel Doeberitz, Loic Le Marchand, Tom GW Letteboer, et al.

Journal article  |  2018  |  Journal of Clinical Oncology

Costs and outcomes of Lynch syndrome screening in the Australian colorectal cancer population

Dayna R Cenin, Steffie K Naber, Iris Lansdorp-Vogelaar, Mark A Jenkins, Daniel D Buchanan, David B Preen, Hooi C Ee, Peter O'Leary

Journal article  |  2018  |  Journal of Gastroenterology and Hepatology

DNA mismatch repair protein deficient non-neoplastic colonic crypts: a novel indicator of Lynch syndrome

Rish K Pai, Beth Dudley, Eve Karloski, Randall E Brand, Neil O'Callaghan, Christophe Rosty, Daniel D Buchanan, Mark A Jenkins, Stephen N Thibodeau, Amy J French, Noralane M Lindor, Reetesh K Pai

Journal article  |  2018  |  Modern Pathology

Discussions about predictive genetic testing for Lynch syndrome: the role of health professionals and families in decisions to decline

Anaita Kanga-Parabia, Clara Gaff, Louisa Flander, Mark Jenkins, Louise A Keogh

Journal article  |  2018  |  Familial Cancer

Sunscreen Use and Melanoma Risk Among Young Australian Adults

Caroline G Watts, Martin Drummond, Chris Goumas, Helen Schmid, Bruce K Armstrong, Joanne F Aitken, Mark A Jenkins, Graham G Giles, John L Hopper, Graham J Mann, Anne E Cust

Journal article  |  2018  |  JAMA Dermatology

Family history-based colorectal cancer screening in Australia: A modelling study of the costs, benefits, and harms of different participation scenarios

Mary Dillon, Louisa Flander, Daniel D Buchanan, Finlay A Macrae, Jon D Emery, Ingrid M Winship, Alex Boussioutas, Graham G Giles, John L Hopper, Mark A Jenkins, Driss Ait Ouakrim

Journal article  |  2018  |  PLOS Medicine

Risk of colorectal cancer for carriers of a germ-line mutation in POLE or POLD1

Daniel D Buchanan, Jenna R Stewart, Mark Clendenning, Christophe Rosty, Khalid Mahmood, Bernard J Pope, Mark A Jenkins, John L Hopper, Melissa C Southey, Finlay A Macrae, Ingrid M Winship, Aung Ko Win

Journal article  |  2018  |  Genet Med

The use of a risk assessment and decision support tool (CRISP) compared with usual care in general practice to increase risk-stratified colorectal cancer screening: study protocol for a randomised controlled trial

Jennifer G Walker, Finlay Macrae, Ingrid Winship, Jasmeen Oberoi, Sibel Saya, Shakira Milton, Adrian Bickerstaffe, James G Dowty, Richard De Abreu Lourenco, Malcolm Clark, Louise Galloway, George Fishman, Fiona M Walter, Louisa Flander, Patty Chondros, Driss Ait Ouakrim, Marie Pirotta, Lyndal Trevena, Mark A Jenkins, Jon D Emery

Journal article  |  2018  |  Trials

Evaluation of the benefits, harms and cost-effectiveness of potential alternatives to iFOBT testing for colorectal cancer screening in Australia

Jie-Bin Lew, D James B St John, Finlay A Macrae, Jon D Emery, Hooi C Ee, Mark A Jenkins, Emily He, Paul Grogan, Michael Caruana, Diana Sarfati, Marjolein JE Greuter, Veerle MH Coupe, Karen Canfell

Journal article  |  2018  |  International Journal of Cancer

Interactions between genetic predictors of gene expression and dietary factors associated with risk of colorectal cancer

Paneen S Petersen, Yu-Ru Su, Sonja I Berndt, Stephanie A Bien, Hermann Brenner, Graham Casey, Andrew T Chan, Jenny Chang-Claude, Jane C Figueiredo, Steven J Gallinger, Robert W Haile, Tabitha A Harrison, Michael Hoffmeister, Mark A Jenkins, Amit D Joshi, Sebastien Kury, Loic Le Marchand, Yi Lin, Noralane M Lindor, Polly A Newcomb, et al.

Conference Proceedings  |  2018  |  Epidemiology

The melanoma genomics managing your risk study: A protocol for a randomized controlled trial evaluating the impact of personal genomic risk information on skin cancer prevention behaviors

Amelia K Smit, Ainsley J Newson, Rachael L Morton, Michael Kimlin, Louise Keogh, Matthew H Law, Judy Kirk, Suzanne Dobbinson, Peter A Kanetsky, Georgina Fenton, Martin Allen, Phyllis Butow, Kate Dunlop, Lyndal Trevena, Serigne Lo, Jacqueline Savard, Hugh Dawkins, Sarah Wordsworth, Mark Jenkins, Graham J Mann, et al.

Journal article  |  2018  |  Contemporary Clinical Trials

Functionally informed genome-wide interaction analysis of nonsteroidal anti-inflammatory drugs on colorectal cancer risk

Xiaoliang Wang, Yu-Ru Su, Andrew T Chan, Stephanie Bien, Sonja I Bernt, Hermann Brenner, Graham Casey, Jenny Chang-Claude, Steven J Gallinger, Robert W Haile, Tabitha A Harrison, Michael Hoffmeister, Mark A Jenkins, Amit Joshi, Yi Lin, Noralane M Lindor, Loic Le Marchand, Hongmei Nan, Polly A Newcomb, John D Potter, et al.

Conference Proceedings  |  2018  |  Epidemiology

Genome-wide association study by colorectal carcinoma subtype

Tabitha A Harrison, Yiwen Lu, Chenjie Zeng, Flora Qu, Kristin Anderson, Hermann Brenner, Daniel D Buchanan, Peter T Campbell, Andrew T Chan, Jenny Chang-Claude, Graham G Giles, Bethany Van Guelpen, Michael Hoffmeister, Mark A Jenkins, Noralane M Lindor, Roger L Milne, Polly A Newcomb, Reiko Nishihara, Michael O Woods, Shuji Ogino, et al.

Conference Proceedings  |  2018  |  Epidemiology

Genetic variation related to innate immunity and colorectal cancer risk

Jessica Citronberg, Barbara Banbury, Andrew T Chan, Peter T Campbell, Graham Casey, Jenny Chang-Claude, Steven J Gallinger, Tabitha Harrison, Michael Hoffmeister, Mark A Jenkins, Loic Le Marchand, Hongmei Nan, Li Jiao, Robert E Schoen, Hermann Brenner, Emily White, Ulrike Peters, Polly A Newcomb

Conference Proceedings  |  2018  |  Epidemiology

Cancer risk and survival in path_MMR carriers by gene and gender up to 75 years of age: a report from the Prospective Lynch Syndrome Database

Pal Moller, Toni T Seppala, Inge Bernstein, Elke Holinski-Feder, Paulo Sala, D Gareth Evans, Annika Lindblom, Finlay Macrae, Ignacio Blanco, Rolf H Sijmons, Jacqueline Jeffries, Hans FA Vasen, John Burn, Sigve Nakken, Eivind Hovig, Einar Andreas Rodland, Kukatharmini Tharmaratnam, Wouter H de Vos Tot Nederveen Cappel, James Hill, Juul T Wijnen, et al.

Journal article  |  2018  |  Gut

Mendelian randomisation study of age at menarche and age at menopause and the risk of colorectal cancer

Sonja Neumeyer, Barbara L Banbury, Volker Arndt, Sonja I Berndt, Stephane Bezieau, Stephanie A Bien, Dan D Buchanan, Katja Butterbach, Bette J Caan, Peter T Campbell, Graham Casey, Andrew T Chan, Stephen J Chanock, James Y Dai, Steven Gallinger, Edward L Giovannucci, Graham G Giles, William M Grady, Jochen Hampe, Michael Hoffmeister, et al.

Journal article  |  2018  |  British Journal of Cancer

'Why don't I need a colonoscopy?' A novel approach to communicating risks and benefits of colorectal cancer screening

Jon D Emery, Marie Pirotta, Finlay Macrae, Jennifer G Walker, Ashleigh Qama, Alex Boussioutas, Mark Jenkins

Journal article  |  2018  |  Australian Journal of General Practice

A Mixed-Effects Model for Powerful Association Tests in Integrative Functional Genomics

Yu-Ru Su, Chongzhi Di, Stephanie Bien, Licai Huang, Xinyuan Dong, Goncalo Abecasis, Sonja Berndt, Stephane Bezieau, Hermann Brenner, Bette Caan, Graham Casey, Jenny Chang-Claude, Stephen Chanock, Sai Chen, Charles Connolly, Keith Curtis, Jane Figueiredo, Manish Gala, Steven Gallinger, Tabitha Harrison, et al.

Journal article  |  2018  |  The American Journal of Human Genetics

Genome-wide association studies (GWASs) have successfully identified thousands of genetic variants for many complex diseases; howe..

POTENTIAL IMPACT OF FAMILY HISTORY BASED SCREENING GUIDELINES ON EARLY CANCER DETECTION AMONG INDIVIDUALS AT RISK FOR YOUNG ONSET COLORECTAL CANCER

Samir Gupta, Balambal Bharti, Dennis Ahnen, Polly Newcomb, Mark Jenkins, Aung Ko Win, D Buchanan, Loic La Marchand, Noralane Lindor, Steven Gallinger, Michelle Cotterchio, Robert Haile, Jane Figueiredo, Iona Cheng, Stephen Thibodeau, Maria Elena Martinez

Conference Proceedings  |  2018  |  GASTROENTEROLOGY

Genetic susceptibility markers for a breast-colorectal cancer phenotype: Exploratory results from genome-wide association studies

Mala Pande, Aron Joon, Abenaa M Brewster, Wei V Chen, John L Hoppers, Cathy Eng, Sanjay Shete, Graham Casey, Fredrick Schumacher, Yi Lin, Tabitha A Harrison, Emily White, Habibul Ahsan, Irene L Andrulis, Alice S Whittemore, Esther M John, Aung Ko Win, Enes Makalic, Daniel F Schmidt, Miroslaw K Kapuscinski, et al.

Journal article  |  2018  |  PLOS ONE

Cohort Profile: The Colon Cancer Family Registry Cohort (CCFRC)

Mark A Jenkins, Aung Ko Win, Allyson S Templeton, Maggie S Angelakos, Daniel D Buchanan, Michelle Cotterchio, Jane C Figueiredo, Stephen N Thibodeau, John A Baron, John D Potter, John L Hopper, Graham Casey, Steven Gallinger, Loic Le Marchand, Noralane M Lindor, Polly A Newcomb, Robert W Haile

Journal article  |  2018  |  International Journal of Epidemiology

The CRISP-Q study Communicating the risks and benefits of colorectal cancer screening

Grace Y Kim, Jennifer Walker, Adrian Bickerstaffe, Nadira Hewabandu, Marie Pirotta, Louisa Flander, Mark Jenkins, Jon Emery

Journal article  |  2018  |  Australian Family Physician

Ability of known susceptibility SNPs to predict colorectal cancer risk for persons with and without a family history

Mark Jenkins, Aung Win, James Dowty, Robert MacInnis, Enes Makalic, Daniel Schmidt, Gillian Dite, Miroslaw Kapuscinski, Mark Clendenning, Christophe Rosty, Ingrid Winship, Jon Emery, Sibel Saya, Finlay Macrae, Dennis Ahnen, David Duggan, Jane Figueiredo, Noralane Lindor, Robert Haile, John Potter, et al.

Journal article  |  2018

ABSTRACT Background A number of single nucleotide polymorphisms (SNPs), which are common inherited genetic variants, have been ide..

Interaction between polymorphisms in aspirin metabolic pathways, regular aspirin use and colorectal cancer risk: A case-control study in unselected white European populations

Harsh Sheth, Emma Northwood, Cornelia M Ulrich, Dominique Scherer, Faye Elliott, Jennifer H Barrett, David Forman, C Roland Wolf, Gillian Smith, Michael S Jackson, Mauro Santibanez-Koref, Robert Haile, Graham Casey, Mark Jenkins, Aung Ko Win, John L Hopper, Loic Le Marchand, Noralane M Lindor, Stephen N Thibodeau, John D Potter, et al.

Journal article  |  2018  |  PLOS ONE

Breast Cancer Risk Associations with Digital Mammographic Density by Pixel Brightness Threshold and Mammographic System

Tuong L Nguyen, Yoon-Ho Choi, Ye K Aung, Christopher F Evans, Nhut H Trinh, Shuai Li, Gillian S Dite, Myeong-Seong Kim, Patrick C Brennan, Mark A Jenkins, Joohon Sung, Yun-Mi Song, John L Hopper

Journal article  |  2018  |  Radiology

Genome-wide association study and meta-analysis in Northern European populations replicate multiple colorectal cancer risk loci

Tomas Tanskanen, Linda van den Berg, Niko Valimaki, Mervi Aavikko, Eivind Ness-Jensen, Kristian Hveem, Yvonne Wettergren, Elinor Bexe Lindskog, Neeme Tonisson, Andres Metspalu, Kaisa Silander, Giulia Orlando, Philip J Law, Sari Tuupanen, Alexandra E Gylfe, Ulrika A Hanninen, Tatiana Cajuso, Johanna Kondelin, Antti-Pekka Sarin, Eero Pukkala, et al.

Journal article  |  2018  |  International Journal of Cancer

Genomic Characterization of Upper-Tract Urothelial Carcinoma in Patients With Lynch Syndrome

Timothy E Donahue, Aditya Bagrodia, Francois Audenet, Mark TA Donoghue, Eugene K Cha, John P Sfakianos, Dahlia Sperling, Hikmat Al-Ahmadie, Mark Clendenning, Christophe Rosty, Daniel D Buchanan, Mark Jenkins, John Hopper, Ingrid Winship, Allyson S Templeton, Michael F Walsh, Zsofia K Stadler, Gopa Iyer, Barry Taylor, Jonathan Coleman, et al.

Journal article  |  2018  |  JCO Precision Oncology

Associations of alcohol intake, smoking, physical activity and obesity with survival following colorectal cancer diagnosis by stage, anatomic site and tumor molecular subtype

Harindra Jayasekara, Dallas R English, Andrew Haydon, Allison M Hodge, Brigid M Lynch, Christophe Rosty, Elizabeth J Williamson, Mark Clendenning, Melissa C Southey, Mark A Jenkins, Robin Room, John L Hopper, Roger L Milne, Daniel D Buchanan, Graham G Giles, Robert J MacInnis

Journal article  |  2018  |  International Journal of Cancer

The International Mismatch Repair Consortium

Mark A Jenkins, Jeanette C Reece, Aung K Win

Book Chapter  |  2018

Somatic mutations of the coding microsatellites within the beta-2-microglobulin gene in mismatch repair-deficient colorectal cancers and adenomas

Mark Clendenning, Alvin Huang, Harindra Jayasekara, Marie Lorans, Susan Preston, Neil O'Callaghan, Bernard J Pope, Finlay A Macrae, Ingrid M Winship, Roger L Milne, Graham G Giles, Dallas R English, John L Hopper, Aung K Win, Mark A Jenkins, Melissa C Southey, Christophe Rosty, Daniel D Buchanan

Journal article  |  2018  |  Familial Cancer

The Colon Cancer Family Registry Cohort

Mark A Jenkins, Aung K Win, Noralane M Lindor

Book Chapter  |  2018

Enrichment of colorectal cancer associations in functional regions: Insight for using epigenomics data in the analysis of whole genome sequence-imputed GWAS data

Stephanie A Bien, Paul L Auer, Tabitha A Harrison, Conghui Qu, Charles M Connolly, Peyton G Greenside, Sai Chen, Sonja I Berndt, Stephane Bezieau, Hyun M Kang, Jeroen Huyghe, Hermann Brenner, Graham Casey, Andrew T Chan, John L Hopper, Barbara L Banbury, Jenny Chang-Claude, Stephen J Chanock, Robert W Haile, Michael Hoffmeister, et al.

Journal article  |  2017  |  PLOS ONE

Inherited variation in circadian rhythm genes and risks of prostate cancer and three other cancer sites in combined cancer consortia

Fangyi Gu, Han Zhang, Paula L Hyland, Sonja Berndt, Susan M Gapstur, William Wheeler, Christopher I Amos, Stephane Bezieau, Heike Bickeboller, Hermann Brenner, Paul Brennan, Jenny Chang-Claude, David V Conti, Jennifer Anne Doherty, Stephen B Gruber, Tabitha A Harrison, Richard B Hayes, Michael Hoffmeister, Richard S Houlston, Rayjean J Hung, et al.

Journal article  |  2017  |  International Journal of Cancer

Colorectal cancer incidence in path_MLH1 carriers subjected to different follow-up protocols: a Prospective Lynch Syndrome Database report

Toni Seppala, Kirsi Pylvanainen, Dafydd Gareth Evans, Heikki Jarvinen, Laura Renkonen-Sinisalo, Inge Bernstein, Elke Holinski-Feder, Paola Sala, Annika Lindblom, Finlay Macrae, Ignacio Blanco, Rolf Sijmons, Jacqueline Jeffries, Hans Vasen, John Burn, Sigve Nakken, Eivind Hovig, Einar Andreas Rodland, Kukatharmini Tharmaratnam, Wouter H de Vos tot Nederveen Cappel, et al.

Journal article  |  2017  |  Hereditary Cancer in Clinical Practice

Pro-inflammatory fatty acid profile and colorectal cancer risk: A Mendelian randomisation analysis

Sebastian May-Wilson, Amit Sud, Philip J Law, Kimmo Palin, Sari Tuupanen, Alexandra Gylfe, Ulrika A Hanninen, Tatiana Cajuso, Tomas Tanskanen, Johanna Kondelin, Eevi Kaasinen, Antti-Pekka Sarin, Johan G Eriksson, Harri Rissanen, Paul Knekt, Eero Pukkala, Pekka Jousilahti, Veikko Salomaa, Samuli Ripatti, Aarno Palotie, et al.

Journal article  |  2017  |  European Journal of Cancer

Incidence of and survival after subsequent cancers in carriers of pathogenic MMR variants with previous cancer: a report from the prospective Lynch syndrome database

Pal Moller, Toni Seppala, Inge Bernstein, Elke Holinski-Feder, Paola Sala, D Gareth Evans, Annika Lindblom, Finlay Macrae, Ignacio Blanco, Rolf Sijmons, Jacqueline Jeffries, Hans Vasen, John Burn, Sigve Nakken, Eivind Hovig, Einar Andreas Rodland, Kukatharmini Tharmaratnam, Wouter H de Vos Tot Nederveen Cappel, James Hill, Juul Wijnen, et al.

Journal article  |  2017  |  Gut

Choosing not to undergo predictive genetic testing for hereditary colorectal cancer syndromes: expanding our understanding of decliners and declining

Louise A Keogh, Heather Niven, Alison Rutstein, Louisa Flander, Clara Gaff, Mark Jenkins

Journal article  |  2017  |  Journal of Behavioral Medicine

Mendelian randomisation implicates hyperlipidaemia as a risk factor for colorectal cancer

Henry Rodriguez-Broadbent, Philip J Law, Amit Sud, Kimmo Palin, Sari Tuupanen, Alexandra Gylfe, Ulrika A Hanninen, Tatiana Cajuso, Tomas Tanskanen, Johanna Kondelin, Eevi Kaasinen, Antti-Pekka Sarin, Samuli Ripatti, Johan G Eriksson, Harri Rissanen, Paul Knekt, Eero Pukkala, Pekka Jousilahti, Veikko Salomaa, Aarno Palotie, et al.

Journal article  |  2017  |  International Journal of Cancer

Lack of evidence for germline RNF43 mutations in patients with serrated polyposis syndrome from a large multinational study

Daniel D Buchanan, Mark Clendenning, Li Zhuoer, Jenna R Stewart, Sharelle Joseland, Sonja Woodall, Julie Arnold, Kara Semotiuk, Melyssa Aronson, Spring Holter, Steven Gallinger, Mark A Jenkins, Kevin Sweet, Finlay A Macrae, Ingrid M Winship, Susan Parry, Christophe Rosty

Journal article  |  2017  |  Gut

Comparison of the efficiency of colorectal cancer screening programs based on age and genetic risk for reduction of colorectal cancer mortality

Oliver Stanesby, Mark Jenkins

Journal article  |  2017  |  European Journal of Human Genetics

Development of a comprehensive colorectal cancer risk prediction tool (CRiPT) incorporating known and unknown major genes and polygenes

Aung Ko Win, Mark A Jenkins, James G Dowty, Antonis C Antoniou, Andrew Lee, Yingye Zheng, Noralane M Lindor, Polly A Newcomb, John L Hopper, Robert J MacInnis

Conference Proceedings  |  2017  |  Improving Cancer Risk Prediction for Prevention and Early Detection

Mammographic density defined by higher than conventional brightness thresholds better predicts breast cancer risk

Tuong L Nguyen, Ye K Aung, Christopher F Evans, Gillian S Dite, Jennifer Stone, Robert J MacInnis, James G Dowty, Adrian Bickerstaffe, Kelly Aujard, Johanna M Rommens, Yun-Mi Song, Joohon Sung, Mark A Jenkins, Melissa C Southey, Graham G Giles, Carmel Apicella, John L Hopper

Journal article  |  2017  |  International Journal of Epidemiology

Cohort Profile: The Tasmanian Longitudinal Health STUDY (TAHS)

Melanie C Matheson, Michael J Abramson, Katrina Allen, Geza Benke, John A Burgess, James G Dowty, Bircan Erbas, Iain H Feather, Peter A Frith, Graham G Giles, Lyle C Gurrin, Garun S Hamilton, John L Hopper, Alan L James, Mark A Jenkins, David P Johns, Caroline J Lodge, Adrian J Lowe, James Markos, Stephen C Morrison, et al.

Journal article  |  2017  |  International Journal of Epidemiology

Lifetime alcohol intake is associated with an increased risk of KRAS plus and BRAF-/KRAS- but not BRAF plus colorectal cancer

Harindra Jayasekara, Robert J MacInnis, Elizabeth J Williamson, Allison M Hodge, Mark Clendenning, Christophe Rosty, Rhiannon Walters, Robin Room, Melissa C Southey, Mark A Jenkins, Roger L Milne, John L Hopper, Graham G Giles, Daniel D Buchanan, Dallas R English

Journal article  |  2017  |  International Journal of Cancer

Testing for Gene-Environment Interactions Using a Prospective Family Cohort Design: Body Mass Index in Early and Later Adulthood and Risk of Breast Cancer

Gillian S Dite, Robert J MacInnis, Adrian Bickerstaffe, James G Dowty, Roger L Milne, Antonis C Antoniou, Prue Weideman, Carmel Apicella, Graham G Giles, Melissa C Southey, Mark A Jenkins, Kelly-Anne Phillips, Aung Ko Win, Mary Beth Terry, John L Hopper

Journal article  |  2017  |  American Journal of Epidemiology

Germline miRNA DNA Variants and the Risk of Colorectal Cancer by Subtype

Noralane M Lindor, Melissa C Larson, Melissa S DeRycke, Shannon K McDonnell, Saurabh Baheti, Zachary C Fogarty, Aung Ko Win, John D Potter, Daniel D Buchanan, Mark Clendenning, Polly A Newcomb, Graham Casey, Steven Gallinger, Loic Le Marchand, John L Hopper, Mark A Jenkins, Ellen L Goode, Stephen N Thibodeau

Journal article  |  2017  |  Genes, Chromosomes and Cancer

Modeling of Successive Cancer Risks in Lynch Syndrome Families in the Presence of Competing Risks Using Copulas

Yun-Hee Choi, Laurent Briollais, Aung K Win, John Hopper, Dan Buchanan, Mark Jenkins, Lajmi Lakhal-Chaieb

Journal article  |  2017  |  Biometrics

Prevalence and Penetrance of Major Genes and Polygenes for Colorectal Cancer

Aung Ko Win, Mark A Jenkins, James G Dowty, Antonis C Antoniou, Andrew Lee, Graham G Giles, Daniel D Buchanan, Mark Clendenning, Christophe Rosty, Dennis J Ahnen, Stephen N Thibodeau, Graham Casey, Steven Gallinger, Loic Le Marchand, Robert W Haile, John D Potter, Yingye Zheng, Noralane M Lindor, Polly A Newcomb, John L Hopper, et al.

Journal article  |  2017  |  Cancer Epidemiology Biomarkers and Prevention

Alcohol Consumption and the Risk of Colorectal Cancer for Mismatch Repair Gene Mutation Carriers

S Ghazaleh Dashti, Daniel D Buchanan, Harindra Jayasekara, Driss Ait Ouakrim, Mark Clendenning, Christophe Rosty, Ingrid M Winship, Finlay A Macrae, Graham G Giles, Susan Parry, Graham Casey, Robert W Haile, Steven Gallinger, Loic Le Marchand, Stephen N Thibodeau, Noralane M Lindor, Polly A Newcomb, John D Potter, John A Baron, John L Hopper, et al.

Journal article  |  2017  |  Cancer Epidemiology Biomarkers and Prevention

Integrating personalised genomics into risk stratification models of population screening for colorectal cancer

Dayna Cenin, Peter O'Leary, Iris Lansdorp-Vogelaar, David Preen, Mark Jenkins, Eric Moses

Journal article  |  2017  |  Australian and New Zealand Journal of Public Health

Tumor testing to identify lynch syndrome in two Australian colorectal cancer cohorts

Daniel D Buchanan, Mark Clendenning, Christophe Rosty, Stine V Eriksen, Michael D Walsh, Rhiannon J Walters, Stephen N Thibodeau, Jenna Stewart, Susan Preston, Aung Ko Win, Louisa Flander, Driss Ait Ouakrim, Finlay A Macrae, Alex Boussioutas, Ingrid M Winship, Graham G Giles, John L Hopper, Melissa C Southey, Dallas English, Mark A Jenkins

Journal article  |  2017  |  Journal of Gastroenterology and Hepatology

Risk factors for metachronous colorectal cancer or polyp: A systematic review and meta-analysis

Harindra Jayasekara, Jeanette C Reece, Daniel D Buchanan, Dennis J Ahnen, Susan Parry, Mark A Jenkins, Aung Ko Win

Journal article  |  2017  |  JOURNAL OF GASTROENTEROLOGY AND HEPATOLOGY

The CRISP colorectal cancer risk prediction tool: an exploratory study using simulated consultations in Australian primary care

Jennifer G Walker, Adrian Bickerstaffe, Nadira Hewabandu, Sanjay Maddumarachchi, James G Dowty Crecrc, Mark Jenkins, Marie Pirotta, Fiona M Walter, Jon D Emery

Journal article  |  2017  |  BMC Medical Informatics and Decision Making

How does genetic risk information for Lynch syndrome translate to risk management behaviours?

Emma Steel, Andrew Robbins, Mark Jenkins, Louisa Flander, Clara Gaff, Louise Keogh

Journal article  |  2017  |  Hereditary Cancer in Clinical Practice

Primary prevention

F Macrae, T Lockett, J Clarke, J Emery, M Jenkins, J McNeil, A Spigelman, A Win, R Woods, G Young, N Pachter, J Zalcbeg, undefined Cancer Council Australia Colorectal Cancer Guidelines Working Party

Book Chapter  |  2017

Colorectal cancer is the second most common non-skin cancer occurring in men and women in Australia, and the second most common ca..

SNP rs16906252C > T Is an Expression and Methylation Quantitative Trait Locus Associated with an Increased Risk of Developing MGMT-Methylated Colorectal Cancer

Joice Kuroiwa-Trzmielina, Fan Wang, Robert W Rapkins, Robyn L Ward, Daniel D Buchanan, Aung Ko Win, Mark Clendenning, Christophe Rosty, Melissa C Southey, Ingrid M Winship, John L Hopper, Mark A Jenkins, Jake Olivier, Nicholas J Hawkins, Megan P Hitchins

Journal article  |  2016  |  Clinical Cancer Research

Risk of extracolonic cancers for people with biallelic and monoallelic mutations in MUTYH

Aung Ko Win, Jeanette C Reece, James G Dowty, Daniel D Buchanan, Mark Clendenning, Christophe Rosty, Melissa C Southey, Joanne P Young, Sean P Cleary, Hyeja Kim, Michelle Cotterchio, Finlay A Macrae, Katherine M Tucker, John A Baron, Terrilea Burnett, Loic Le Marchand, Graham Casey, Robert W Haile, Polly A Newcomb, Stephen N Thibodeau, et al.

Journal article  |  2016  |  INTERNATIONAL JOURNAL OF CANCER

Genome-Wide Interaction Analyses between Genetic Variants and Alcohol Consumption and Smoking for Risk of Colorectal Cancer

Jian Gong, Carolyn M Hutter, Polly A Newcomb, Cornelia M Ulrich, Stephanie A Bien, Peter T Campbell, John A Baron, Sonja I Berndt, Stephane Bezieau, Hermann Brenner, Graham Casey, Andrew T Chan, Jenny Chang-Claude, Mengmeng Du, David Duggan, Jane C Figueiredo, Steven Gallinger, Edward L Giovannucci, Robert W Haile, Tabitha A Harrison, et al.

Journal article  |  2016  |  PLOS Genetics

Colorectal cancer screening is cost-effective in the elderly who have had less intense prior screening, high baseline risk of colorectal cancer and less comorbidities.

Mark Jenkins

Journal article  |  2016  |  Evidence Based Medicine

Common variants in the obesity-associated genes FTO and MC4R are not associated with risk of colorectal cancer

Baiyu Yang, Aaron P Thrift, Jane C Figueiredo, Mark A Jenkins, Fredrick R Schumacher, David V Conti, Yi Lin, Aung Ko Win, Paul J Limburg, Sonja I Berndt, Hermann Brenner, Andrew T Chan, Jenny Chang-Claude, Michael Hoffmeister, Thomas J Hudson, Loic Le Marchand, Polly A Newcomb, Martha L Slattery, Emily White, Ulrike Peters, et al.

Journal article  |  2016  |  Cancer Epidemiology

Associations of 5HTTLPR polymorphism with major depressive disorder and alcohol dependence: A systematic review and meta-analysis

Khine Zin Oo, Ye Kyaw Aung, Mark A Jenkins, Aung Ko Win

Journal article  |  2016  |  Australian & New Zealand Journal of Psychiatry

Cross-Cancer Genome-Wide Analysis of Lung, Ovary, Breast, Prostate, and Colorectal Cancer Reveals Novel Pleiotropic Associations

Gordon Fehringer, Peter Kraft, Paul D Pharoah, Rosalind A Eeles, Nilanjan Chatterjee, Fredrick R Schumacher, Joellen M Schildkraut, Sara Lindstrom, Paul Brennan, Heike Bickeboller, Richard S Houlston, Maria Teresa Landi, Neil Caporaso, Angela Risch, Ali Amin Al Olama, Sonja I Berndt, Edward L Giovannucci, Henrik Gronberg, Zsofia Kote-Jarai, Jing Ma, et al.

Journal article  |  2016  |  Cancer Research

Risk factors for metachronous colorectal cancer following a primary colorectal cancer: A prospective cohort study

Harindra Jayasekara, Jeanette C Reece, Daniel D Buchanan, Christophe Rosty, S Ghazaleh Dashti, Driss Ait Ouakrim, Ingrid M Winship, Finlay A Macrae, Alex Boussioutas, Graham G Giles, Dennis J Ahnen, Jan Lowery, Graham Casey, Robert W Haile, Steven Gallinger, Loic Le Marchand, Polly A Newcomb, Noralane M Lindor, John L Hopper, Susan Parry, et al.

Journal article  |  2016  |  INTERNATIONAL JOURNAL OF CANCER

Association between Adult Height and Risk of Colorectal, Lung, and Prostate Cancer: Results from Meta-analyses of Prospective Studies and Mendelian Randomization Analyses

Nikhil K Khankari, Xiao-Ou Shu, Wanqing Wen, Peter Kraft, Sara Lindstrom, Ulrike Peters, Joellen Schildkraut, Fredrick Schumacher, Paolo Bofetta, Angela Risch, Heike Bickeboeller, Christopher I Amos, Douglas Easton, Rosalind A Eeles, Stephen B Gruber, Christopher A Haiman, David J Hunter, Stephen J Chanock, Brandon L Pierce, Wei Zheng

Journal article  |  2016  |  PLOS Medicine

Development and External Validation of a Melanoma Risk Prediction Model Based on Self-assessed Risk Factors

Kylie Vuong, Bruce K Armstrong, Elisabete Weiderpass, Eiliv Lund, Hans-Olov Adami, Marit B Veierod, Jennifer H Barrett, John R Davies, D Timothy Bishop, David C Whiteman, Catherine M Olsen, John L Hopper, Graham J Mann, Anne E Cust, Kevin McGeechan

Journal article  |  2016  |  JAMA Dermatology

Genetically Predicted Body Mass Index and Breast Cancer Risk: Mendelian Randomization Analyses of Data from 145,000 Women of European Descent

Yan Guo, Shaneda Warren Andersen, Xiao-Ou Shu, Kyriaki Michailidou, Manjeet K Bolla, Qin Wang, Montserrat Garcia-Closas, Roger L Milne, Marjanka K Schmidt, Jenny Chang-Claude, Allison Dunning, Stig E Bojesen, Habibul Ahsan, Kristiina Aittomaki, Irene L Andrulis, Hoda Anton-Culver, Volker Arndt, Matthias W Beckmann, Alicia Beeghly-Fadiel, Javier Benitez, et al.

Journal article  |  2016  |  PLOS Medicine

Cholecystectomy and the risk of colorectal cancer by tumor mismatch repair deficiency status

Jie Shang, Jeanette C Reece, Daniel D Buchanan, Graham G Giles, Jane C Figueiredo, Graham Casey, Steven Gallinger, Stephen N Thibodeau, Noralane M Lindor, Polly A Newcomb, John D Potter, John A Baron, John L Hopper, Mark A Jenkins, Aung Ko Win

Journal article  |  2016  |  International Journal of Colorectal Disease

Mendelian randomisation analysis strongly implicates adiposity with risk of developing colorectal cancer

David Jarvis, Jonathan S Mitchell, Philip J Law, Kimmo Palin, Sari Tuupanen, Alexandra Gylfe, Ulrika A Hanninen, Tatiana Cajuso, Tomas Tanskanen, Johanna Kondelin, Eevi Kaasinen, Antti-Pekka Sarin, Jaakko Kaprio, Johan G Eriksson, Harri Rissanen, Paul Knekt, Eero Pukkala, Pekka Jousilahti, Veikko Salomaa, Samuli Ripatti, et al.

Journal article  |  2016  |  British Journal of Cancer

Fine-Mapping of Common Genetic Variants Associated with Colorectal Tumor Risk Identified Potential Functional Variants

Mengmeng Du, Shuo Jiao, Stephanie A Bien, Manish Gala, Goncalo Abecasis, Stephane Bezieau, Hermann Brenner, Katja Butterbach, Bette J Caan, Christopher S Carlson, Graham Casey, Jenny Chang-Claude, David V Conti, Keith R Curtis, David Duggan, Steven Gallinger, Robert W Haile, Tabitha A Harrison, Richard B Hayes, Michael Hoffmeister, et al.

Journal article  |  2016  |  PLOS ONE

Variation at 2q35 (PNKD and TMBIM1) influences colorectal cancer risk and identifies a pleiotropic effect with inflammatory bowel disease

Giulia Orlando, Philip J Law, Kimmo Palin, Sari Tuupanen, Alexandra Gylfe, Ulrika A Hanninen, Tatiana Cajuso, Tomas Tanskanen, Johanna Kondelin, Eevi Kaasinen, Antti-Pekka Sarin, Jaakko Kaprio, Johan G Eriksson, Harri Rissanen, Paul Knekt, Eero Pukkala, Pekka Jousilahti, Veikko Salomaa, Samuli Ripatti, Aarno Palotie, et al.

Journal article  |  2016  |  Human Molecular Genetics

Multivitamin, calcium and folic acid supplements and the risk of colorectal cancer in Lynch syndrome

Rowena Chau, Seyedeh Ghazaleh Dashti, Driss Ait Ouakrim, Daniel D Buchanan, Mark Clendenning, Christophe Rosty, Ingrid M Winship, Joanne P Young, Graham G Giles, Finlay A Macrae, Alex Boussioutas, Susan Parry, Jane C Figueiredo, A Joan Levine, Dennis J Ahnen, Graham Casey, Robert W Haile, Steven Gallinger, Loic Le Marchand, Stephen N Thibodeau, et al.

Journal article  |  2016  |  International Journal of Epidemiology

Identification of Susceptibility Loci and Genes for Colorectal Cancer Risk

Chenjie Zeng, Koichi Matsuda, Wei-Hua Jia, Jiang Chang, Sun-Seog Kweon, Yong-Bing Xiang, Aesun Shin, Sun Ha Jee, Dong-Hyun Kim, Ben Zhang, Qiuyin Cai, Xingyi Guo, Jirong Long, Nan Wang, Regina Courtney, Zhi-Zhong Pan, Chen Wu, Atsushi Takahashi, Min-Ho Shin, Keitaro Matsuo, et al.

Journal article  |  2016  |  Gastroenterology

Determining the familial risk distribution of colorectal cancer: a data mining approach

Rowena Chau, Mark A Jenkins, Daniel D Buchanan, Driss Ait Ouakrim, Graham G Giles, Graham Casey, Steven Gallinger, Robert W Haile, Loic Le Marchand, Polly A Newcomb, Noralane M Lindor, John L Hopper, Aung Ko Win

Journal article  |  2016  |  Familial Cancer

GWASeq: targeted re-sequencing follow up to GWAS

Matthew P Salomon, Wai Lok Sibon Li, Christopher K Edlund, John Morrison, Barbara K Fortini, Aung Ko Win, David V Conti, Duncan C Thomas, David Duggan, Daniel D Buchanan, Mark A Jenkins, John L Hopper, Steven Gallinger, Loic Le Marchand, Polly A Newcomb, Graham Casey, Paul Marjoram

Journal article  |  2016  |  BMC Genomics

Comparison of Prediction Models for Lynch Syndrome Among Individuals With Colorectal Cancer

Fay Kastrinos, Rohit P Ojha, Celine Leenen, Carmelita Alvero, Rowena C Mercado, Judith Balmana, Irene Valenzuela, Francesc Balaguer, Roger Green, Noralane M Lindor, Stephen N Thibodeau, Polly Newcomb, Aung Ko Win, Mark Jenkins, Daniel D Buchanan, Lucio Bertario, Paola Sala, Heather Hampel, Sapna Syngal, Ewout W Steyerberg

Journal article  |  2016  |  JNCI: Journal of the National Cancer Institute

Childhood body mass index and adult mammographic density measures that predict breast cancer risk

John L Hopper, Tuong L Nguyen, Jennifer Stone, Kelly Aujard, Melanie C Matheson, Michael J Abramson, John A Burgess, E Haydn Walters, Gillian S Dite, Minh Bui, Christopher Evans, Enes Makalic, Daniel F Schmidt, Gail Ward, Mark A Jenkins, Graham G Giles, Shyamali C Dharmage, Carmel Apicella

Journal article  |  2016  |  Breast Cancer Research and Treatment

Germline mutations in PMS2 and MLH1 in individuals with solitary loss of PMS2 expression in colorectal carcinomas from the Colon Cancer Family Registry Cohort

Christophe Rosty, Mark Clendenning, Michael D Walsh, Stine V Eriksen, Melissa C Southey, Ingrid M Winship, Finlay A Macrae, Alex Boussioutas, Nicola K Poplawski, Susan Parry, Julie Arnold, Joanne P Young, Graham Casey, Robert W Haile, Steven Gallinger, Loic Le Marchand, Polly A Newcomb, John D Potter, Melissa DeRycke, Noralane M Lindor, et al.

Journal article  |  2016  |  BMJ Open

CYP24A1 variant modifies the association between use of oestrogen plus progestogen therapy and colorectal cancer risk

Xabier Garcia-Albeniz, Anja Rudolph, Carolyn Hutter, Emily White, Yi Lin, Stephanie A Rosse, Jane C Figueiredo, Tabitha A Harrison, Shuo Jiao, Hermann Brenner, Graham Casey, Thomas J Hudson, Mark Thornquist, Loic Le Marchand, John Potter, Martha L Slattery, Brent Zanke, John A Baron, Bette J Caan, Stephen J Chanock, et al.

Journal article  |  2016  |  British Journal of Cancer

Quantifying the utility of single nucleotide polymorphisms to guide colorectal cancer screening

Mark A Jenkins, Enes Makalic, James G Dowty, Daniel F Schmidt, Gillian S Dite, Robert J MacInnis, Driss Ait Ouakrim, Mark Clendenning, Louisa B Flander, Oliver K Stanesby, John L Hopper, Aung K Win, Daniel D Buchanan

Journal article  |  2016  |  Future Oncology

PMS2 monoallelic mutation carriers: the known unknown

McKinsey L Goodenberger, Brittany C Thomas, Douglas Riegert-Johnson, C Richard Boland, Sharon E Plon, Mark Clendenning, Aung Ko Win, Leigha Senter, Steven M Lipkin, Zsofia K Stadler, Finlay A Macrae, Henry T Lynch, Jeffrey N Weitzel, Albert de la Chapelle, Sapna Syngal, Patrick Lynch, Susan Parry, Mark A Jenkins, Steven Gallinger, Spring Holter, et al.

Journal article  |  2016  |  Genetics in Medicine

Lynch syndrome and cervical cancer

Yoland C Antill, James G Dowty, Aung Ko Win, Tina Thompson, Michael D Walsh, Margaret C Cummings, Steven Gallinger, Noralane M Lindor, Loic Le Marchand, John L Hopper, Polly A Newcomb, Robert W Haile, James Church, Katherine M Tucker, Daniel D Buchanan, Joanne P Young, Ingrid M Winship, Mark A Jenkins

Journal article  |  2015  |  International Journal of Cancer

Childhood cancers in families with and without Lynch syndrome

John A Heath, Jeanette C Reece, Daniel D Buchanan, Graham Casey, Carol A Durno, Steven Gallinger, Robert W Haile, Polly A Newcomb, John D Potter, Stephen N Thibodeau, Loic Le Marchand, Noralane M Lindor, John L Hopper, Mark A Jenkins, Aung Ko Win

Journal article  |  2015  |  Familial Cancer

Risk of colorectal cancer for people with a mutation in both a MUTYH and a DNA mismatch repair gene

Aung Ko Win, Jeanette C Reece, Daniel D Buchanan, Mark Clendenning, Joanne P Young, Sean P Cleary, Hyeja Kim, Michelle Cotterchio, James G Dowty, Robert J MacInnis, Katherine M Tucker, Ingrid M Winship, Finlay A Macrae, Terrilea Burnett, Loic Le Marchand, Graham Casey, Robert W Haile, Polly A Newcomb, Stephen N Thibodeau, Noralane M Lindor, et al.

Journal article  |  2015  |  Familial Cancer

Meta-analysis of genome-wide association studies identifies common susceptibility polymorphisms for colorectal and endometrial cancer near SH2B3 and TSHZ1

Timothy HT Cheng, Deborah Thompson, Jodie Painter, Tracy O'Mara, Maggie Gorman, Lynn Martin, Claire Palles, Angela Jones, Daniel D Buchanan, Aung Ko Win, John Hopper, Mark Jenkins, Noralane M Lindor, Polly A Newcomb, Steve Gallinger, David Conti, Fred Schumacher, Graham Casey, Graham G Giles, Paul Pharoah, et al.

Journal article  |  2015  |  Scientific Reports

Mammographic density defined by higher than conventional brightness threshold better predicts breast cancer risk for full-field digital mammograms

Tuong Linh Nguyen, Ye Kyaw Aung, Christopher Francis Evans, Choi Yoon-Ho, Mark Anthony Jenkins, Joohon Sung, John Llewelyn Hopper, Yun-Mi Song

Journal article  |  2015  |  Breast Cancer Research

Genetic variants within the hTERT gene and the risk of colorectal cancer in Lynch syndrome.

Aung Ko Win, Mark Clendenning, William Crawford, Christophe Rosty, Susan G Preston, Melissa C Southey, Susan Parry, Graham G Giles, Finlay A Macrae, Ingrid M Winship, John A Baron, John L Hopper, Mark A Jenkins, Daniel D Buchanan

Journal article  |  2015  |  Genes & Cancer

Lynch syndrome is an inherited cancer-predisposing disorder caused by germline mutations in the DNA mismatch repair (MMR) genes bu..

A genome-wide association study for colorectal cancer identifies a risk locus in 14q23.1

Mathieu Lemire, Conghui Qu, Lenora WM Loo, Syed HE Zaidi, Hansong Wang, Sonja I Berndt, Stephane Bezieau, Hermann Brenner, Peter T Campbell, Andrew T Chan, Jenny Chang-Claude, Mengmeng Du, Christopher K Edlund, Steven Gallinger, Robert W Haile, Tabitha A Harrison, Michael Hoffmeister, John L Hopper, Lifang Hou, Li Hsu, et al.

Journal article  |  2015  |  Human Genetics

Mutation Spectrum and Risk of Colorectal Cancer in African American Families with Lynch Syndrome

Rodrigo Santa Cruz Guindalini, Aung Ko Win, Cassandra Gulden, Noralane M Lindor, Polly A Newcomb, Robert W Haile, Victoria Raymond, Elena Stoffel, Michael Hall, Xavier Llor, Chinedu I Ukaegbu, Ilana Solomon, Jeffrey Weitzel, Matthew Kalady, Amie Blanco, Jonathan Terdiman, Gladis A Shuttlesworth, Patrick M Lynch, Heather Hampel, Henry T Lynch, et al.

Journal article  |  2015  |  Gastroenterology

Trends in colorectal cancer mortality in Europe: retrospective analysis of the WHO mortality database

Driss Ait Ouakrim, Cecile Pizot, Magali Boniol, Matteo Malvezzi, Mathieu Boniol, Eva Negri, Maria Bota, Mark A Jenkins, Harry Bleiberg, Philippe Autier

Journal article  |  2015  |  BMJ

Identification of a common variant with potential pleiotropic effect on risk of inflammatory bowel disease and colorectal cancer

Hamed Khalili, Jian Gong, Hermann Brenner, Thomas R Austin, Carolyn M Hutter, Yoshifumi Baba, John A Baron, Sonja I Berndt, Stephane Bezieau, Bette Caan, Peter T Campbell, Jenny Chang-Claude, Stephen J Chanock, Constance Chen, Li Hsu, Shuo Jiao, David V Conti, David Duggan, Charles S Fuchs, Manish Gala, et al.

Journal article  |  2015  |  Carcinogenesis

Fertility after young-onset colorectal cancer: a study of subjects with Lynch syndrome

D Stupart, AK Win, IM Winship, M Jenkins

Journal article  |  2015  |  Colorectal Disease

1054 Risk of extracolonic cancers for people with biallelic and monoallelic mutations in MUTYH

A Win, J Reece, J Dowty, D Buchanan, M Clendenning, J Young, S Cleary, M Cotterchio, F Macrae, J Baron, L Le Marchand, G Casey, R Haile, P Newcomb, S Thibodeau, J Hopper, S Gallinger, I Winship, N Lindor, M Jenkins

Conference Proceedings  |  2015  |  European Journal of Cancer

Aspirin, Ibuprofen, and the Risk for Colorectal Cancer in Lynch Syndrome

Driss Ait Ouakrim, Seyedeh Ghazaleh Dashti, Rowena Chau, Daniel D Buchanan, Mark Clendenning, Christophe Rosty, Ingrid M Winship, Joanne P Young, Graham G Giles, Barbara Leggett, Finlay A Macrae, Dennis J Ahnen, Graham Casey, Steven Gallinger, Robert W Haile, Loic Le Marchand, Stephen N Thibodeau, Noralane M Lindor, Polly A Newcomb, John D Potter, et al.

Journal article  |  2015  |  Journal of the National Cancer Institute

Association between Body Mass Index and Mortality for Colorectal Cancer Survivors: Overall and by Tumor Molecular Phenotype

Peter T Campbell, Christina C Newton, Polly A Newcomb, Amanda I Phipps, Dennis J Ahnen, John A Baron, Daniel D Buchanan, Graham Casey, Sean P Cleary, Michelle Cotterchio, Alton B Farris, Jane C Figueiredo, Steven Gallinger, Roger C Green, Robert W Haile, John L Hopper, Mark A Jenkins, Loic Le Marchand, Karen W Makar, John R McLaughlin, et al.

Journal article  |  2015  |  Cancer Epidemiology Biomarkers & Prevention

Researchers Uncover Novel Spatially Defined Stem Cells

Tracy Hampton

Journal article  |  2015  |  JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION

Female Hormonal Factors and the Risk of Endometrial Cancer in Lynch Syndrome

Seyedeh Ghazaleh Dashti, Rowena Chau, Driss Ait Ouakrim, Daniel D Buchanan, Mark Clendenning, Joanne P Young, Ingrid M Winship, Julie Arnold, Dennis J Ahnen, Robert W Haile, Graham Casey, Steven Gallinger, Stephen N Thibodeau, Noralane M Lindor, Loic Le Marchand, Polly A Newcomb, John D Potter, John A Baron, John L Hopper, Mark A Jenkins, et al.

Journal article  |  2015  |  JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION

Genome-wide association study of colorectal cancer identifies six new susceptibility loci

Fredrick R Schumacher, Stephanie L Schmit, Shuo Jiao, Christopher K Edlund, Hansong Wang, Ben Zhang, Li Hsu, Shu-Chen Huang, Christopher P Fischer, John F Harju, Gregory E Idos, Flavio Lejbkowicz, Frank J Manion, Kevin McDonnell, Caroline E McNeil, Marilena Melas, Hedy S Rennert, Wei Shi, Duncan C Thomas, David J Van Den Berg, et al.

Journal article  |  2015  |  Nature Communications

Prediagnostic Physical Activity and Colorectal Cancer Survival: Overall and Stratified by Tumor Characteristics

Sheetal Hardikar, Polly A Newcomb, Peter T Campbell, Aung Ko Win, Noralane M Lindor, Daniel D Buchanan, Karen W Makar, Mark A Jenkins, John D Potter, Amanda I Phipps

Journal article  |  2015  |  Cancer Epidemiology Biomarkers & Prevention

Mendelian Randomization Study of Body Mass Index and Colorectal Cancer Risk

Aaron P Thrift, Jian Gong, Ulrike Peters, Jenny Chang-Claude, Anja Rudolph, Martha L Slattery, Andrew T Chan, Adame Locke, Bratati Kahali, Anne E Justice, Tune H Pers, Steven Gallinger, Richard B Hayes, John A Baron, Bette J Caan, Shuji Ogino, Sonja I Berndt, Stephen J Chanock, Graham Casey, Robert W Haile, et al.

Journal article  |  2015  |  Cancer Epidemiology Biomarkers & Prevention

Consequences of germline variation disrupting the constitutional translational initiation codon start sites of MLH1 and BRCA2: Use of potential alternative start sites and implications for predicting variant pathogenicity

Michael T Parsons, Phillip J Whiley, Jonathan Beesley, Mark Drost, Niels de Wind, Bryony A Thompson, Louise Marquart, John L Hopper, Mark A Jenkins, Melissa A Brown, Kathy Tucker, Linda Warwick, Daniel D Buchanan, Amanda B Spurdle

Journal article  |  2015  |  Molecular Carcinogenesis

A new GWAS and meta-analysis with 1000Genomes imputation identifies novel risk variants for colorectal cancer (vol 5, 10442, 2015)

Nada A Al-Tassan, Nicola Whiffin, Fay J Hosking, Claire Palles, Susan M Farrington, Sara E Dobbins, Rebecca Harris, Maggie Gorman, Albert Tenesa, Brian F Meyer, Salma M Wakil, Ben Kinnersley, Harry Campbell, Lynn Martin, Christopher G Smith, Shelley Idziaszczyk, Ella Barclay, Timothy S Maughan, Richard Kaplan, Rachel Kerr, et al.

Journal article  |  2015  |  Scientific Reports

A new GWAS and meta-analysis with 1000Genomes imputation identifies novel risk variants for colorectal cancer

Nada A Al-Tassan, Nicola Whiffin, Fay J Hosking, Claire Palles, Susan M Farrington, Sara E Dobbins, Rebecca Harris, Maggie Gorman, Albert Tenesa, Brian F Meyer, Salma M Wakil, Ben Kinnersley, Harry Campbell, Lynn Martin, Christopher G Smith, Shelley Idziaszczyk, Ella Barclay, Timothy S Maughan, Richard Kaplan, Rachel Kerr, et al.

Journal article  |  2015  |  Scientific Reports

Inhibition of CD23-mediated IgE transcytosis suppresses the initiation and development of airway allergic inflammation

Senthilkumar Palaniyandi, Xiaoyang Liu, Sivakumar Periasamy, Aiying Ma, Jin Tang, Mark Jenkins, Wenbin Tuo, Wenxia Song, Achsah Keegan, Daniel Conrad, Xiaoping Zhu

Conference Proceedings  |  2015  |  Mucosal Immunology

Germline TP53 Mutations in Patients With Early-Onset Colorectal Cancer in the Colon Cancer Family Registry

Matthew B Yurgelun, Serena Masciari, Victoria A Joshi, Rowena C Mercado, Noralane M Lindor, Steven Gallinger, John L Hopper, Mark A Jenkins, Daniel D Buchanan, Polly A Newcomb, John D Potter, Robert W Haile, Raju Kucherlapati, Sapna Syngal

Journal article  |  2015  |  JAMA Oncology

Accuracy of Self-Reported Nevus and Pigmentation Phenotype Compared with Clinical Assessment in a Population-Based Study of Young Australian Adults

Anne E Cust, Kristen M Pickles, Chris Goumas, Thao Vu, Helen Schmid, Eduardo Nagore, John Kelly, Joanne F Aitken, Graham G Giles, John L Hopper, Mark A Jenkins, Graham J Mann

Journal article  |  2015  |  Cancer Epidemiology Biomarkers & Prevention

Mendelian randomization study of height and risk of colorectal cancer

Aaron P Thrift, Jian Gong, Ulrike Peters, Jenny Chang-Claude, Anja Rudolph, Martha L Slattery, Andrew T Chan, Tonu Esko, Andrew R Wood, Jian Yang, Sailaja Vedantam, Stefan Gustafsson, Tune H Pers, John A Baron, Stephane Bezieau, Sebastien Kuery, Shuji Ogino, Sonja I Berndt, Graham Casey, Robert W Haile, et al.

Journal article  |  2015  |  International Journal of Epidemiology

Association of Aspirin and NSAID Use With Risk of Colorectal Cancer According to Genetic Variants

Hongmei Nan, Carolyn M Hutter, Yi Lin, Eric J Jacobs, Cornelia M Ulrich, Emily White, John A Baron, Sonja I Berndt, Hermann Brenner, Katja Butterbach, Bette J Caan, Peter T Campbell, Christopher S Carlson, Graham Casey, Jenny Chang-Claude, Stephen J Chanock, Michelle Cotterchio, David Duggan, Jane C Figueiredo, Charles S Fuchs, et al.

Journal article  |  2015  |  JAMA

Common colorectal cancer risk alleles contribute to the multiple colorectal adenoma phenotype, but do not influence colonic polyposis in FAP

Timothy HT Cheng, Maggie Gorman, Lynn Martin, Ella Barclay, Graham Casey, Brian Saunders, Huw Thomas, Sue Clark, Ian Tomlinson

Journal article  |  2015  |  European Journal of Human Genetics

Short-Term Risk of Colorectal Cancer in Individuals With Lynch Syndrome: A Meta-Analysis

Mark A Jenkins, James G Dowty, Driss Ait Ouakrim, John D Mathews, John L Hopper, Youenn Drouet, Christine Lasset, Valerie Bonadona, Aung Ko Win

Journal article  |  2015  |  Journal of Clinical Oncology

Role of tumour molecular and pathology features to estimate colorectal cancer risk for first-degree relatives

Aung Ko Win, Daniel D Buchanan, Christophe Rosty, Robert J MacInnis, James G Dowty, Gillian S Dite, Graham G Giles, Melissa C Southey, Joanne P Young, Mark Clendenning, Michael D Walsh, Rhiannon J Walters, Alex Boussioutas, Thomas C Smyrk, Stephen N Thibodeau, John A Baron, John D Potter, Polly A Newcomb, Loic Le Marchand, Robert W Haile, et al.

Journal article  |  2015  |  Gut

Red Meat Intake, NAT2, and Risk of Colorectal Cancer: A Pooled Analysis of 11 Studies

Ashwin N Ananthakrishnan, Mengmeng Du, Sonja I Berndt, Hermann Brenner, Bette J Caan, Graham Casey, Jenny Chang-Claude, David Duggan, Charles S Fuchs, Steven Gallinger, Edward L Giovannucci, Tabitha A Harrison, Richard B Hayes, Michael Hoffmeister, John L Hopper, Lifang Hou, Li Hsu, Mark A Jenkins, Peter Kraft, Jing Ma, et al.

Journal article  |  2015  |  Cancer Epidemiology Biomarkers & Prevention

High prevalence of mismatch repair deficiency in prostate cancers diagnosed in mismatch repair gene mutation carriers from the colon cancer family registry

Christophe Rosty, Michael D Walsh, Noralane M Lindor, Stephen N Thibodeau, Erin Mundt, Steven Gallinger, Melyssa Aronson, Aaron Pollett, John A Baron, Sally Pearson, Mark Clendenning, Rhiannon J Walters, Belinda N Nagler, William J Crawford, Joanne P Young, Ingrid Winship, Aung Ko Win, John L Hopper, Mark A Jenkins, Daniel D Buchanan

Journal article  |  2014  |  Familial Cancer

No Evidence of Gene-Calcium Interactions from Genome-Wide Analysis of Colorectal Cancer Risk

Mengmeng Du, Xuehong Zhang, Michael Hoffmeister, Robert E Schoen, John A Baron, Sonja I Berndt, Hermann Brenner, Christopher S Carlson, Graham Casey, Andrew T Chan, Keith R Curtis, David Duggan, W James Gauderman, Edward L Giovannucci, Jian Gong, Tabitha A Harrison, Richard B Hayes, Brian E Henderson, John L Hopper, Li Hsu, et al.

Journal article  |  2014  |  Cancer Epidemiology Biomarkers & Prevention

Prevalence and predictors of germline CDKN2A mutations for melanoma cases from Australia, Spain and the United Kingdom

Mark Harland, Anne E Cust, Celia Badenas, Yu-Mei Chang, Elizabeth A Holland, Paula Aguilera, Joanne F Aitken, Bruce K Armstrong, Jennifer H Barrett, Cristina Carrera, May Chan, Joanne Gascoyne, Graham G Giles, Chantelle Agha-Hamilton, John L Hopper, Mark A Jenkins, Peter A Kanetsky, Richard F Kefford, Isabel Kolm, Johanna Lowery, et al.

Journal article  |  2014  |  Hereditary Cancer in Clinical Practice

A novel colorectal cancer risk locus at 4q32.2 identified from an international genome-wide association study

Stephanie L Schmit, Fredrick R Schumacher, Christopher K Edlund, David V Conti, Leon Raskin, Flavio Lejbkowicz, Mila Pinchev, Hedy S Rennert, Mark A Jenkins, John L Hopper, Daniel D Buchanan, Noralane M Lindor, Loic Le Marchand, Steven Gallinger, Robert W Haile, Polly A Newcomb, Shu-Chen Huang, Gad Rennert, Graham Casey, Stephen B Gruber

Journal article  |  2014  |  Carcinogenesis

Should the grading of colorectal adenocarcinoma include microsatellite instability status?

Christophe Rosty, Elizabeth J Williamson, Mark Clendenning, Rhiannon J Walters, Aung K Win, Mark A Jenkins, John L Hopper, Ingrid M Winship, Melissa C Southey, Graham G Giles, Dallas R English, Daniel D Buchanan

Journal article  |  2014  |  Human Pathology

Identification of a melanoma susceptibility locus and somatic mutation in TET2

Fengju Song, Christopher I Amos, Jeffrey E Lee, Christine G Lian, Shenying Fang, Hongliang Liu, Stuart MacGregor, Mark M Iles, Matthew H Law, Neal I Lindeman, Grant W Montgomery, David L Duffy, Anne E Cust, Mark A Jenkins, David C Whiteman, Richard F Kefford, Graham G Giles, Bruce K Armstrong, Joanne F Aitken, John L Hopper, et al.

Journal article  |  2014  |  Carcinogenesis

Gene-Environment Interaction Involving Recently Identified Colorectal Cancer Susceptibility Loci

Elizabeth D Kantor, Carolyn M Hutter, Jessica Minnier, Sonja I Berndt, Hermann Brenner, Bette J Caan, Peter T Campbell, Christopher S Carlson, Graham Casey, Andrew T Chan, Jenny Chang-Claude, Stephen J Chanock, Michelle Cotterchio, Mengmeng Du, David Duggan, Charles S Fuchs, Edward L Giovannucci, Jian Gong, Tabitha A Harrison, Richard B Hayes, et al.

Journal article  |  2014  |  Cancer Epidemiology Biomarkers & Prevention

Fertility and apparent genetic anticipation in Lynch syndrome

Douglas Stupart, Aung Ko Win, Mark Jenkins, Ingrid M Winship, Paul Goldberg, Rajkumar Ramesar

Journal article  |  2014  |  Familial Cancer

Identification of susceptibility loci for colorectal cancer in a genome-wide meta-analysis

Nicola Whiffin, Fay J Hosking, Susan M Farrington, Claire Palles, Sara E Dobbins, Lina Zgaga, Amy Lloyd, Ben Kinnersley, Maggie Gorman, Albert Tenesa, Peter Broderick, Yufei Wang, Ella Barclay, Caroline Hayward, Lynn Martin, Daniel D Buchanan, Aung Ko Win, John Hopper, Mark Jenkins, Noralane M Lindor, et al.

Journal article  |  2014  |  Human Molecular Genetics

Trans-ethnic genome-wide association study of colorectal cancer identifies a new susceptibility locus in VTI1A

Hansong Wang, Terrilea Burnett, Suminori Kono, Christopher A Haiman, Motoki Iwasaki, Lynne R Wilkens, Lenora WM Loo, David Van den Berg, Laurence N Kolonel, Brian E Henderson, Temitope O Keku, Robert S Sandler, Lisa B Signorello, William J Blot, Polly A Newcomb, Mala Pande, Christopher I Amos, Dee W West, Stephane Bezieau, Sonja I Berndt, et al.

Journal article  |  2014  |  Nature Communications

Re: Microsatellite Instability and BRAF Mutation Testing in Colorectal Cancer Prognostication

Christophe Rosty, Elizabeth J Wiliamson, Mark Clendening, Rhianon J Walters, Michael D Walsh, Aung K Win, Mark A Jenkins, John L Hoper, Ingrid Winship, Melisa C Southey, Graham G Giles, Dalas R English, Daniel D Buchanan

Journal article  |  2014  |  JNCI Journal of the National Cancer Institute

Family History of Colorectal Cancer Is Not Associated with Colorectal Cancer Survival Regardless of Microsatellite Instability Status

Amanda I Phipps, Dennis J Ahnen, Peter T Campbell, Aung Ko Win, Mark A Jenkins, Noralane M Lindor, Robert Gryfe, John D Potter, Polly A Newcomb

Journal article  |  2014  |  Cancer Epidemiology, Biomarkers & Prevention

Characterisation of Familial Colorectal Cancer Type X, Lynch syndrome, and non-familial colorectal cancer

S Shiovitz, WK Copeland, MN Passarelli, AN Burnett-Hartman, WM Grady, JD Potter, S Gallinger, DD Buchanan, C Rosty, AK Win, M Jenkins, SN Thibodeau, R Haile, JA Baron, LL Marchand, PA Newcomb, NM Lindor

Journal article  |  2014  |  British Journal of Cancer

Genetic Variation in UGT Genes Modify the Associations of NSAIDs with Risk of Colorectal Cancer: Colon Cancer Family Registry

Dominique Scherer, Lisel M Koepl, Elizabeth M Poole, Yesilda Balavarca, Liren Xiao, John A Baron, Li Hsu, Anna E Coghill, Peter T Campbell, Sarah E Kleinstein, Jane C Figueiredo, Johanna W Lampe, Katharina Buck, John D Potter, Richard J Kulmacz, Mark A Jenkins, John L Hopper, Aung K Win, Polly A Newcomb, Cornelia M Ulrich, et al.

Journal article  |  2014  |  Genes, Chromosomes & Cancer

Occupational sun exposure and risk of melanoma according to anatomical site

Kylie Vuong, Kevin McGeechan, Bruce K Armstrong, Anne E Cust

Journal article  |  2014  |  International Journal of Cancer

Although sunburn and intermittent sun exposures are associated with increased melanoma risk, most studies have found null or inver..

Does risk of endometrial cancer for women without a germline mutation in a DNA mismatch repair gene depend on family history of endometrial cancer or colorectal cancer?

Rajani Bharati, Mark A Jenkins, Noralane M Lindor, Loic Le Marchand, Steven Gallinger, Robert W Haile, Polly A Newcomb, John L Hopper, Aung Ko Win

Journal article  |  2014  |  Gynecologic Oncology

Pleiotropic effects of genetic risk variants for other cancers on colorectal cancer risk: PAGE, GECCO and CCFR consortia

Iona Cheng, Jonathan M Kocarnik, Logan Dumitrescu, Noralane M Lindor, Jenny Chang-Claude, Christy L Avery, Christian P Caberto, Shelly-Ann Love, Martha L Slattery, Andrew T Chan, John A Baron, Lucia A Hindorff, Sungshim Lani Park, Fredrick R Schumacher, Michael Hoffmeister, Peter Kraft, Anne M Butler, David J Duggan, Lifang Hou, Chris S Carlson, et al.

Journal article  |  2014  |  Gut

Risk of Colorectal Cancer for Carriers of Mutations in MUTYH, With and Without a Family History of Cancer

Aung Ko Win, James G Dowty, Sean P Cleary, Hyeja Kim, Daniel D Buchanan, Joanne P Young, Mark Clendenning, Christophe Rosty, Robert J MacInnis, Graham G Giles, Alex Boussioutas, Finlay A Macrae, Susan Parry, Jack Goldblatt, John A Baron, Terrilea Burnett, Loic Le Marchand, Polly A Newcomb, Robert W Haile, John L Hopper, et al.

Journal article  |  2014  |  Gastroenterology

Cost-effectiveness of family history-based colorectal cancer screening in Australia

Driss A Ouakrim, Alex Boussioutas, Trevor Lockett, John L Hopper, Mark A Jenkins

Journal article  |  2014  |  BMC Cancer

Genome-Wide Diet-Gene Interaction Analyses for Risk of Colorectal Cancer

Jane C Figueiredo, Li Hsu, Carolyn M Hutter, Yi Lin, Peter T Campbell, John A Baron, Sonja I Berndt, Shuo Jiao, Graham Casey, Barbara Fortini, Andrew T Chan, Michelle Cotterchio, Mathieu Lemire, Steven Gallinger, Tabitha A Harrison, Loic Le Marchand, Polly A Newcomb, Martha L Slattery, Bette J Caan, Christopher S Carlson, et al.

Journal article  |  2014  |  PLoS Genetics

A Genome-wide Association Study of Early-Onset Breast Cancer Identifies PFKM as a Novel Breast Cancer Gene and Supports a Common Genetic Spectrum for Breast Cancer at Any Age

Habibul Ahsan, Jerry Halpern, Muhammad G Kibriya, Brandon L Pierce, Lin Tong, Eric Gamazon, Valerie McGuire, Anna Felberg, Jianxin Shi, Farzana Jasmine, Shantanu Roy, Rachelle Brutus, Maria Argos, Stephanie Melkonian, Jenny Chang-Claude, Irene Andrulis, John L Hopper, Esther M John, Kathi Malone, Giske Ursin, et al.

Journal article  |  2014  |  Cancer Epidemiology, Biomarkers & Prevention

Risk of Prostate Cancer in Lynch Syndrome: A Systematic Review and Meta-analysis

Shae Ryan, Mark A Jenkins, Aung Ko Win

Journal article  |  2014  |  Cancer Epidemiology, Biomarkers & Prevention

Contribution of MC1R Genotype and Novel Common Genomic Variants to Melanoma Risk Prediction

AE Cust, M Bui, C Goumas, MA Jenkins

Conference Proceedings  |  2014  |  Cancer Epidemiology Biomarkers & Prevention

The Association of Telomere Length with Colorectal Cancer Differs by the Age of Cancer Onset

Lisa A Boardman, Kristin Litzelman, Songwon Seo, Ruth A Johnson, Russell J Vanderboom, Grace W Kimmel, Julie M Cunningham, Ronald E Gangnon, Corinne D Engelman, Douglas L Riegert-Johnson, John Potter, Robert Haile, Daniel Buchanan, Mark A Jenkins, David N Rider, Stephen N Thibodeau, Gloria M Petersen, Halcyon G Skinner

Journal article  |  2014  |  Clinical and Translational Gastroenterology

Application of a 5-tiered scheme for standardized classification of 2,360 unique mismatch repair gene variants in the InSiGHT locus-specific database

Bryony A Thompson, Amanda B Spurdle, John-Paul Plazzer, Marc S Greenblatt, Kiwamu Akagi, Fahd Al-Mulla, Bharati Bapat, Inge Bernstein, Gabriel Capella, Johan T den Dunnen, Desiree du Sart, Aurelie Fabre, Michael P Farrell, Susan M Farrington, Ian M Frayling, Thierry Frebourg, David E Goldgar, Christopher D Heinen, Elke Holinski-Feder, Maija Kohonen-Corish, et al.

Journal article  |  2014  |  Nature Genetics

Predictive Genetic Testing of a Bone Marrow Recipient-Ethical Issues Involving Unexpected Results, Gender Issues, Test Accuracy, and Implications for the Donor

A Sexton, L Rawlings, M Jenkins, I Winship

Journal article  |  2014  |  Journal of Genetic Counseling

Perceived Versus Predicted Risks of Colorectal Cancer and Self-Reported Colonoscopies by Members of Mismatch Repair Gene Mutation-Carrying Families Who Have Declined Genetic Testing

Louisa Flander, Andrew Speirs-Bridge, Alison Rutstein, Heather Niven, Aung Ko Win, Driss Ait Ouakrim, John L Hopper, Finlay Macrae, Louise Keogh, Clara Gaff, Mark Jenkins

Journal article  |  2014  |  Journal of Genetic Counseling

Risk profiling: Familial colorectal cancer

AK Win, DA Ouakrim, MA Jenkins

Journal article  |  2014  |  Cancer Forum

Deciphering the genetic architecture of low-penetrance susceptibility to colorectal cancer

Nicola Whiffin, Sara E Dobbins, Fay J Hosking, Claire Palles, Albert Tenesa, Yufei Wang, Susan M Farrington, Angela M Jones, Peter Broderick, Harry Campbell, Polly A Newcomb, Graham Casey, David V Conti, Fred Schumacher, Steve Gallinger, Noralane M Lindor, John Hopper, Mark Jenkins, Malcolm G Dunlop, Ian P Tomlinson, et al.

Journal article  |  2013  |  Human Molecular Genetics

Expression of MUC2, MUC5AC, MUC5B, and MUC6 mucins in colorectal cancers and their association with the CpG island methylator phenotype

Michael D Walsh, Mark Clendenning, Elizabeth Williamson, Sally-Ann Pearson, Rhiannon J Walters, Belinda Nagler, David Packenas, Aung K Win, John L Hopper, Mark A Jenkins, Andrew M Haydon, Christophe Rosty, Dallas R English, Graham G Giles, Michael A McGuckin, Joanne P Young, Daniel D Buchanan

Journal article  |  2013  |  Modern Pathology

Criteria and prediction models for mismatch repair gene mutations: a review

Aung Ko Win, Robert J MacInnis, James G Dowty, Mark A Jenkins

Journal article  |  2013  |  Journal of Medical Genetics

Re: Risks of Colorectal and Other Cancers After Endometrial Cancer for Women With Lynch Syndrome Response

Aung Ko Win, Mark A Jenkins

Journal article  |  2013  |  Journal of the National Cancer Institute

Genetic Predictors of Circulating 25-Hydroxyvitamin D and Risk of Colorectal Cancer

Linda T Hiraki, Conghui Qu, Carolyn M Hutter, John A Baron, Sonja I Berndt, Stephane Bezieau, Hermann Brenner, Bette J Caan, Graham Casey, Jenny Chang-Claude, Stephen J Chanock, David V Conti, David Duggan, Charles S Fuchs, Steven Gallinger, Edward L Giovannucci, Tabitha A Harrison, Richard B Hayes, Aditi Hazra, Brian Henderson, et al.

Journal article  |  2013  |  Cancer Epidemiology, Biomarkers & Prevention

Telomere Length Varies By DNA Extraction Method: Implications for Epidemiologic Research

Julie M Cunningham, Ruth A Johnson, Kristin Litzelman, Halcyon G Skinner, Songwon Seo, Corinne D Engelman, Russell J Vanderboom, Grace W Kimmel, Ronald E Gangnon, Douglas L Riegert-Johnson, John A Baron, John D Potter, Robert Haile, Daniel D Buchanan, Mark A Jenkins, David N Rider, Stephen N Thibodeau, Gloria M Petersen, Lisa A Boardman

Journal article  |  2013  |  Cancer Epidemiology, Biomarkers & Prevention

BRAFV600E Immunohistochemistry Facilitates Universal Screening of Colorectal Cancers for Lynch Syndrome

Christopher W Toon, Michael D Walsh, Angela Chou, David Capper, Adele Clarkson, Loretta Sioson, Stephen Clarke, Scott Mead, Rhiannon J Walters, Mark Clendenning, Christophe Rosty, Joanne P Young, Aung Ko Win, John L Hopper, Ashley Crook, Andreas von Deimling, Mark A Jenkins, Daniel D Buchanan, Anthony J Gill

Journal article  |  2013  |  American Journal of Surgical Pathology

A new regulatory variant in the interleukin-6 receptor gene associates with asthma risk

JA Revez, L Bain, B Chapman, JE Powell, R Jansen, DL Duffy, JY Tung, BW Penninx, PM Visscher, EJC De Geus, DI Boomsma, DA Hinds, NG Martin, GW Montgomery, MAR Ferreira

Journal article  |  2013  |  Genes & Immunity

Is the reported modifying effect of 8q23.3 and 11q23.1 on colorectal cancer risk for MLH1 mutation carriers valid?

Aung Ko Win, Mark A Jenkins

Journal article  |  2013  |  International Journal of Cancer

MC1R genotype as a predictor of early-onset melanoma, compared with self-reported and physician-measured traditional risk factors: an Australian case-control-family study

Anne E Cust, Chris Goumas, Kylie Vuong, John R Davies, Jennifer H Barrett, Elizabeth A Holland, Helen Schmid, Chantelle Agha-Hamilton, Bruce K Armstrong, Richard F Kefford, Joanne F Aitken, Graham G Giles, D Timothy Bishop, Julia A Newton-Bishop, John L Hopper, Graham J Mann, Mark A Jenkins

Journal article  |  2013  |  BMC Cancer

Detection of large scale 3 ' deletions in the PMS2 gene amongst Colon-CFR participants: have we been missing anything?

Mark Clendenning, Michael D Walsh, Judith Balmana Gelpi, Stephen N Thibodeau, Noralane Lindor, John D Potter, Polly Newcomb, Loic LeMarchand, Robert Haile, Steve Gallinger, John L Hopper, Mark A Jenkins, Christophe Rosty, Joanne P Young, Daniel D Buchanan

Journal article  |  2013  |  Familial Cancer

Trends in colorectal cancer mortality and screening activities in European countries

P Autier, D Ait Ouakrim, M Malvezzi, H Bleiberg, M Jenkins, M Boniol, E Negri

Conference Proceedings  |  2013  |  EUROPEAN JOURNAL OF CANCER

Screening participation for people at increased risk of colorectal cancer due to family history: a systematic review and meta-analysis

Driss Ait Ouakrim, Trevor Lockett, Alex Boussioutas, John L Hopper, Mark A Jenkins

Journal article  |  2013  |  Familial Cancer

Germline HOXB13 p.Gly84Glu mutation and risk of colorectal cancer

Mohammad R Akbari, Laura N Anderson, Daniel D Buchanan, Mark Clendenning, Mark A Jenkins, Aung Ko Win, John L Hopper, Graham G Giles, Robert Nam, Steven Narod, Steven Gallinger, Sean P Cleary

Journal article  |  2013  |  Cancer Epidemiology

Colon and Rectal Cancer Survival by Tumor Location and Microsatellite Instability: The Colon Cancer Family Registry

Amanda I Phipps, Noralane M Lindor, Mark A Jenkins, John A Baron, Aung Ko Win, Steven Gallinger, Robert Gryfe, Polly A Newcomb

Journal article  |  2013  |  Diseases of the Colon and Rectum

Lynch syndrome-associated breast cancers do not overexpress chromosome 11-encoded mucins

Michael D Walsh, Margaret C Cummings, Sally-Ann Pearson, Mark Clendenning, Rhiannon J Walters, Belinda Nagler, John L Hopper, Mark A Jenkins, Graeme K Suthers, Jack Goldblatt, Kathy Tucker, Michael R Gattas, Julie L Arnold, Susan Parry, Finlay A Macrae, Michael A McGuckin, Joanne P Young, Daniel D Buchanan

Journal article  |  2013  |  Modern Pathology

Association between hypermethylation of DNA repetitive elements in white blood cell DNA and early-onset colorectal cancer

Rhiannon J Walters, Elizabeth J Williamson, Dallas R English, Joanne P Young, Christophe Rosty, Mark Clendenning, Michael D Walsh, Susan Parry, Dennis J Ahnen, John A Baron, Aung Ko Win, Graham G Giles, John L Hopper, Mark A Jenkins, Daniel D Buchanan

Journal article  |  2013  |  Epigenetics

Identification of Novel Variants in Colorectal Cancer Families by High-Throughput Exome Sequencing

Melissa S DeRycke, Shanaka R Gunawardena, Sumit Middha, Yan W Asmann, Daniel J Schaid, Shannon K McDonnell, Shaun M Riska, Bruce W Eckloff, Julie M Cunningham, Brooke L Fridley, Daniel J Serie, William R Bamlet, Mine S Cicek, Mark A Jenkins, David J Duggan, Daniel Buchanan, Mark Clendenning, Robert W Haile, Michael O Woods, Steven N Gallinger, et al.

Journal article  |  2013  |  Cancer Epidemiology, Biomarkers & Prevention

Germline Mutations in the Polyposis-Associated Genes BMPR1A, SMAD4, PTEN, MUTYH and GREM1 Are Not Common in Individuals with Serrated Polyposis Syndrome

Mark Clendenning, Joanne P Young, Michael D Walsh, Sonja Woodall, Julie Arnold, Mark Jenkins, Aung Ko Win, John L Hopper, Kevin Sweet, Steven Gallinger, Christophe Rosty, Susan Parry, Daniel D Buchanan

Journal article  |  2013  |  PLoS One

PIK3CA Activating Mutation in Colorectal Carcinoma: Associations with Molecular Features and Survival

Christophe Rosty, Joanne P Young, Michael D Walsh, Mark Clendenning, Kristy Sanderson, Rhiannon J Walters, Susan Parry, Mark A Jenkins, Aung Ko Win, Melissa C Southey, John L Hopper, Graham G Giles, Elizabeth J Williamson, Dallas R English, Daniel D Buchanan

Journal article  |  2013  |  PLoS One

Risk of Metachronous Colon Cancer Following Surgery for Rectal Cancer in Mismatch Repair Gene Mutation Carriers

Aung Ko Win, Susan Parry, Bryan Parry, Matthew F Kalady, Finlay A Macrae, Dennis J Ahnen, Graeme P Young, Lara Lipton, Ingrid Winship, Alex Boussioutas, Joanne P Young, Daniel D Buchanan, Julie Arnold, Loic Le Marchand, Polly A Newcomb, Robert W Haile, Noralane M Lindor, Steven Gallinger, John L Hopper, Mark A Jenkins

Journal article  |  2013  |  Annals of Surgical Oncology

Colorectal carcinomas with KRAS mutation are associated with distinctive morphological and molecular features

Christophe Rosty, Joanne P Young, Michael D Walsh, Mark Clendenning, Rhiannon J Walters, Sally Pearson, Erika Pavluk, Belinda Nagler, David Pakenas, Jeremy R Jass, Mark A Jenkins, Aung Ko Win, Melissa C Southey, Susan Parry, John L Hopper, Graham G Giles, Elizabeth Williamson, Dallas R English, Daniel D Buchanan

Journal article  |  2013  |  Modern Pathology

Dilemma in Pulmonary Metastasectomy Video-Assisted Thoracoscopic Surgery or Thoracotomy? Response

Jens Eckardt, Peter Bjorn Licht

Journal article  |  2013  |  Chest

Absence of PMS2 mutations in colon-CFR participants whose colorectal cancers demonstrate unexplained loss of MLH1 expression

M Clendenning, FA Macrae, MD Walsh, RJ Walters, SN Thibodeau, SR Gunawardena, JD Potter, RW Haile, S Gallinger, JL Hopper, MA Jenkins, C Rosty, JP Young, DD Buchanan

Journal article  |  2013  |  Clinical Genetics

Cumulative impact of common genetic variants and other risk factors on colorectal cancer risk in 42 103 individuals

Malcolm G Dunlop, Albert Tenesa, Susan M Farrington, Stephane Ballereau, David H Brewster, Thibaud Koessler, Paul Pharoah, Clemens Schafmayer, Jochen Hampe, Henry Voelzke, Jenny Chang-Claude, Michael Hoffmeister, Hermann Brenner, Susanna von Holst, Simone Picelli, Annika Lindblom, Mark A Jenkins, John L Hopper, Graham Casey, David Duggan, et al.

Journal article  |  2013  |  Gut

Screening Participation Predictors for People at Familial Risk of Colorectal Cancer A Systematic Review

Driss Ait Ouakrim, Trevor Lockett, Alex Boussioutas, Louise Keogh, Louisa B Flander, John L Hopper, Mark A Jenkins

Journal article  |  2013  |  American Journal of Preventive Medicine

Family History of Colorectal Cancer in BRAF p.V600E-Mutated Colorectal Cancer Cases

Daniel D Buchanan, Aung K Win, Michael D Walsh, Rhiannon J Walters, Mark Clendenning, Belinda Nagler, Sally-Ann Pearson, Finlay A Macrae, Susan Parry, Julie Arnold, Ingrid Winship, Graham G Giles, Noralane M Lindor, John D Potter, John L Hopper, Christophe Rosty, Joanne P Young, Mark A Jenkins

Journal article  |  2013  |  Cancer Epidemiology, Biomarkers & Prevention

Are the common genetic variants associated with colorectal cancer risk for DNA mismatch repair gene mutation carriers?

Aung Ko Win, John L Hopper, Daniel D Buchanan, Joanne P Young, Albert Tenesa, James G Dowty, Graham G Giles, Jack Goldblatt, Ingrid Winship, Alex Boussioutas, Graeme P Young, Susan Parry, John A Baron, David Duggan, Steven Gallinger, Polly A Newcomb, Robert W Haile, Loic Le Marchand, Noralane M Lindor, Mark A Jenkins

Journal article  |  2013  |  European Journal of Cancer

Genetic Variations in SMAD7 Are Associated with Colorectal Cancer Risk in the Colon Cancer Family Registry

Xuejuan Jiang, J Esteban Castelao, David Vandenberg, Angel Carracedo, Carmen M Redondo, David V Conti, Jesus P Paredes Cotore, John D Potter, Polly A Newcomb, Michael N Passarelli, Mark A Jenkins, John L Hopper, Steven Gallinger, Loic Le Marchand, Maria E Martinez, Dennis J Ahnen, John A Baron, Noralane M Lindor, Robert W Haile, Manuela Gago-Dominguez

Journal article  |  2013  |  PLoS One

A variant in FTO shows association with melanoma risk not due to BMI

Mark M Iles, Matthew H Law, Simon N Stacey, Jiali Han, Shenying Fang, Ruth Pfeiffer, Mark Harland, Stuart MacGregor, John C Taylor, Katja K Aben, Lars A Akslen, Marie-Francoise Avril, Esther Azizi, Bert Bakker, Kristrun R Benediktsdottir, Wilma Bergman, Giovanna Bianchi Scarra, Kevin M Brown, Donato Calista, Valerie Chaudru, et al.

Journal article  |  2013  |  Nature Genetics

Identification of Genetic Susceptibility Loci for Colorectal Tumors in a Genome-Wide Meta-analysis

Ulrike Peters, Shuo Jiao, Fredrick R Schumacher, Carolyn M Hutter, Aaron K Aragaki, John A Baron, Sonja I Berndt, Stephane Bezieau, Hermann Brenner, Katja Butterbach, Bette J Caan, Peter T Campbell, Christopher S Carlson, Graham Casey, Andrew T Chan, Jenny Chang-Claude, Stephen J Chanock, Lin S Chen, Gerhard A Coetzee, Simon G Coetzee, et al.

Journal article  |  2013  |  Gastroenterology

Multiplicity and Molecular Heterogeneity of Colorectal Carcinomas in Individuals With Serrated Polyposis

Christophe Rosty, Michael D Walsh, Rhiannon J Walters, Mark Clendenning, Sally-Ann Pearson, Mark A Jenkins, Aung Ko Win, John L Hopper, Kevin Sweet, Wendy L Frankel, Melyssa Aronson, Steve Gallinger, Jack Goldblatt, Kathy Tucker, Sian Greening, Michael R Gattas, Sonja Woodall, Julie Arnold, Neal I Walker, Susan Parry, et al.

Journal article  |  2013  |  American Journal of Surgical Pathology

Cancer Risks for MLH1 and MSH2 Mutation Carriers

James G Dowty, Aung K Win, Daniel D Buchanan, Noralane M Lindor, Finlay A Macrae, Mark Clendenning, Yoland C Antill, Stephen N Thibodeau, Graham Casey, Steve Gallinger, Loic Le Marchand, Polly A Newcomb, Robert W Haile, Graeme P Young, Paul A James, Graham G Giles, Shanaka R Gunawardena, Barbara A Leggett, Michael Gattas, Alex Boussioutas, et al.

Journal article  |  2013  |  Human Mutation

Recurrent and founder mutations in the PMS2 gene

J Tomsic, L Senter, S Liyanarachchi, M Clendenning, CP Vaughn, MA Jenkins, JL Hopper, J Young, W Samowitz, A de la Chapelle

Journal article  |  2013  |  Clinical Genetics

Population-Based Estimate of Prostate Cancer Risk for Carriers of the HOXB13 Missense Mutation G84E

Robert J MacInnis, Gianluca Severi, Laura Baglietto, James G Dowty, Mark A Jenkins, Melissa C Southey, John L Hopper, Graham G Giles

Journal article  |  2013  |  PLoS One

Risks of Colorectal and Other Cancers After Endometrial Cancer for Women With Lynch Syndrome

Aung Ko Win, Noralane M Lindor, Ingrid Winship, Katherine M Tucker, Daniel D Buchanan, Joanne P Young, Christophe Rosty, Barbara Leggett, Graham G Giles, Jack Goldblatt, Finlay A Macrae, Susan Parry, Matthew F Kalady, John A Baron, Dennis J Ahnen, Loic Le Marchand, Steven Gallinger, Robert W Haile, Polly A Newcomb, John L Hopper, et al.

Journal article  |  2013  |  Journal of the National Cancer Institute

A Multifactorial Likelihood Model for MMR Gene Variant Classification Incorporating Probabilities Based on Sequence Bioinformatics and Tumor Characteristics: A Report from the Colon Cancer Family Registry

Bryony A Thompson, David E Goldgar, Carol Paterson, Mark Clendenning, Rhiannon Walters, Sven Arnold, Michael T Parsons, Michael D Walsh, Steven Gallinger, Robert W Haile, John L Hopper, Mark A Jenkins, Loic LeMarchand, Noralane M Lindor, Polly A Newcomb, Stephen N Thibodeau, Joanne P Young, Daniel D Buchanan, Sean V Tavtigian, Amanda B Spurdle

Journal article  |  2013  |  Human Mutation

Risk of breast cancer in Lynch syndrome: a systematic review

Aung Ko Win, Noralane M Lindor, Mark A Jenkins

Journal article  |  2013  |  Breast Cancer Research

Genome-Wide Search for Gene-Gene Interactions in Colorectal Cancer

Shuo Jiao, Li Hsu, Sonja Berndt, Stephane Bezieau, Hermann Brenner, Daniel Buchanan, Bette J Caan, Peter T Campbell, Christopher S Carlson, Graham Casey, Andrew T Chan, Jenny Chang-Claude, Stephen Chanock, David V Conti, Keith R Curtis, David Duggan, Steven Gallinger, Stephen B Gruber, Tabitha A Harrison, Richard B Hayes, et al.

Journal article  |  2012  |  PLoS One

Identification of Risk Genes through Whole Exome Sequencing in the Colon Cancer Family Registry

Melissa S DeRycke, Shanaka R Gunawardena, Shannon K McDonnell, Shaun M Riska, Yan W Asmann, Sumit Middha, Daniel J Schaid, Bruce W Eckloff, Stephen N Thibodeau, Noralane M Lindor, John L Hopper, Mark A Jenkins, Daniel D Buchanen, Michael Woods, Robert W Haile, Graham Casey, John A Baron, Steve Gallinger, Ellen L Goode

Conference Proceedings  |  2012  |  GENETIC EPIDEMIOLOGY

Does eczema in infancy cause hay fever, asthma, or both in childhood? Insights from a novel regression model of sibling data

John L Hopper, Quang M Bui, Bircan Erbas, Melanie C Matheson, Lyle C Gurrin, John A Burgess, Adrian J Lowe, Mark A Jenkins, Michael J Abramson, E Haydn Walters, Graham G Giles, Shyamali C Dharmage

Journal article  |  2012  |  Journal of Allergy and Clinical Immunology

Screening practices of Australian men and women categorized as "at or slightly above average risk" of colorectal cancer

Driss Ait Ouakrim, Trevor Lockett, Alex Boussioutas, Louise Keogh, Louisa B Flander, Ingrid Winship, Graham G Giles, John L Hopper, Mark A Jenkins

Journal article  |  2012  |  Cancer Causes & Control

Identification of Lynch Syndrome Among Patients With Colorectal Cancer

Leticia Moreira, Francesc Balaguer, Noralane Lindor, Albert de la Chapelle, Heather Hampel, Lauri A Aaltonen, John L Hopper, Loic Le Marchand, Steven Gallinger, Polly A Newcomb, Robert Haile, Stephen N Thibodeau, Shanaka Gunawardena, Mark A Jenkins, Daniel D Buchanan, John D Potter, John A Baron, Dennis J Ahnen, Victor Moreno, Montserrat Andreu, et al.

Journal article  |  2012  |  JAMA: Journal of the American Medical Association

Risks of Primary Extracolonic Cancers Following Colorectal Cancer in Lynch Syndrome

Aung Ko Win, Noralane M Lindor, Joanne P Young, Finlay A Macrae, Graeme P Young, Elizabeth Williamson, Susan Parry, Jack Goldblatt, Lara Lipton, Ingrid Winship, Barbara Leggett, Katherine M Tucker, Graham G Giles, Daniel D Buchanan, Mark Clendenning, Christophe Rosty, Julie Arnold, A Joan Levine, Robert W Haile, Steven Gallinger, et al.

Journal article  |  2012  |  Journal of the National Cancer Institute

Reasons for ongoing participation in a longitudinal cohort study

Christopher A Barton, Cathryn May, Desiree Meszaros, Melanie C Matheson, Mark Jenkins, Graham Giles, John Hopper, E Haydn Walters, Shyamali C Dharmage, Michael J Abramson

Journal article  |  2012  |  Australian and New Zealand Journal of Public Health

MC1R genotypes and risk of melanoma before age 40 years: A population-based case-control-family study

Anne E Cust, Chris Goumas, Elizabeth A Holland, Chantelle Agha-Hamilton, Joanne F Aitken, Bruce K Armstrong, Graham G Giles, Richard F Kefford, Helen Schmid, John L Hopper, Graham J Mann, Mark A Jenkins

Journal article  |  2012  |  International Journal of Cancer

Body size and risk for colorectal cancers showing BRAF mutations or microsatellite instability: a pooled analysis

Laura AE Hughes, Elizabeth J Williamson, Manon van Engeland, Mark A Jenkins, Graham G Giles, John L Hopper, Melissa C Southey, Joanne P Young, Daniel D Buchanan, Michael D Walsh, Piet A van den Brandt, R Alexandra Goldbohm, Matty P Weijenberg, Dallas R English

Journal article  |  2012  |  International Journal of Epidemiology

Performance of PREM1,2,6, MMRpredict, and MMRpro in detecting Lynch syndrome among endometrial cancer cases

Rowena C Mercado, Heather Hampel, Fay Kastrinos, Ewout Steyerberg, Judith Balmana, Elena Stoffel, David E Cohn, Floor J Backes, John L Hopper, Mark A Jenkins, Noralane M Lindor, Graham Casey, Robert Haile, Subha Madhavan, Albert de la Chapelle, Sapna Syngal

Journal article  |  2012  |  Genetics in Medicine

Common variation near CDKN1A, POLD3 and SHROOM2 influences colorectal cancer risk

Malcolm G Dunlop, Sara E Dobbins, Susan Mary Farrington, Angela M Jones, Claire Palles, Nicola Whiffin, Albert Tenesa, Sarah Spain, Peter Broderick, Li-Yin Ooi, Enric Domingo, Claire Smillie, Marc Henrion, Matthew Frampton, Lynn Martin, Graeme Grimes, Maggie Gorman, Colin Semple, Yusanne P Ma, Ella Barclay, et al.

Journal article  |  2012  |  Nature Genetics

Phenotype and Polyp Landscape in Serrated Polyposis Syndrome: A Series of 100 Patients From Genetics Clinics

Christophe Rosty, Daniel D Buchanan, Michael D Walsh, Sally-Ann Pearson, Erika Pavluk, Rhiannon J Walters, Mark Clendenning, Kevin J Spring, Mark A Jenkins, Aung K Win, John L Hopper, Kevin Sweet, Wendy L Frankel, Melyssa Aronson, Steve Gallinger, Jack Goldblatt, Sonja Woodall, Julie Arnold, Neal I Walker, Jeremy R Jass, et al.

Journal article  |  2012  |  American Journal of Surgical Pathology

Colorectal Cancer Linkage on Chromosomes 4q21, 8q13, 12q24, and 15q22

Mine S Cicek, Julie M Cunningham, Brooke L Fridley, Daniel J Serie, William R Bamlet, Brenda Diergaarde, Robert W Haile, Loic Le Marchand, Theodore G Krontiris, H Banfield Younghusband, Steven Gallinger, Polly A Newcomb, John L Hopper, Mark A Jenkins, Graham Casey, Fredrick Schumacher, Zhu Chen, Melissa S DeRycke, Allyson S Templeton, Ingrid Winship, et al.

Journal article  |  2012  |  PLoS One

Kaplan-Meier failure estimate for metachronous colorectal cancer risk is clinically relevant

Mark A Jenkins, Lyle C Gurrin, Susan Parry, Aung Ko Win

Journal article  |  2012  |  Gut

Immunohistochemical testing of conventional adenomas for loss of expression of mismatch repair proteins in Lynch syndrome mutation carriers: a case series from the Australasian site of the colon cancer family registry

Michael D Walsh, Daniel D Buchanan, Sally-Ann Pearson, Mark Clendenning, Mark A Jenkins, Aung Ko Win, Rhiannon J Walters, Kevin J Spring, Belinda Nagler, Erika Pavluk, Sven T Arnold, Jack Goldblatt, Jill George, Graeme K Suthers, Kerry Phillips, John L Hopper, Jeremy R Jass, John A Baron, Dennis J Ahnen, Stephen N Thibodeau, et al.

Journal article  |  2012  |  Modern Pathology

Cancer Risks for Relatives of Patients With Serrated Polyposis

Aung Ko Win, Rhiannon J Walters, Daniel D Buchanan, Mark A Jenkins, Kevin Sweet, Wendy L Frankel, Albert de la Chapelle, Diane M McKeone, Michael D Walsh, Mark Clendenning, Sally-Ann Pearson, Erika Pavluk, Belinda Nagler, John L Hopper, Michael R Gattas, Jack Goldblatt, Jill George, Graeme K Suthers, Kerry D Phillips, Sonja Woodall, et al.

Journal article  |  2012  |  American Journal of Gastroenterology

Role of Environmental Risk Factors on Early-Onset Colorectal Cancer Risk

Aung Ko Win, Sergio A Taunde, Joanne P Young, Daniel D Buchanan, Driss Ait Ouakrim, Noralane M Lindor, Loic Le Marchand, Steven Gallinger, Michelle Cotterchio, Polly A Newcomb, Robert W Haile, John Hopper, Mark A Jenkins

Conference Proceedings  |  2012  |  GASTROENTEROLOGY

Colorectal and Other Cancer Risks for Carriers and Noncarriers From Families With a DNA Mismatch Repair Gene Mutation: A Prospective Cohort Study

Aung Ko Win, Joanne P Young, Noralane M Lindor, Katherine M Tucker, Dennis J Ahnen, Graeme P Young, Daniel D Buchanan, Mark Clendenning, Graham G Giles, Ingrid Winship, Finlay A Macrae, Jack Goldblatt, Melissa C Southey, Julie Arnold, Stephen N Thibodeau, Shanaka R Gunawardena, Bharati Bapat, John A Baron, Graham Casey, Steven Gallinger, et al.

Journal article  |  2012  |  Journal of Clinical Oncology

Risk Prediction Models for Colorectal Cancer: A Review

Aung Ko Win, Robert J MacInnis, John L Hopper, Mark A Jenkins

Journal article  |  2012  |  Cancer Epidemiology, Biomarkers & Prevention