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Prof

Mark Jenkins

Nhmrc Professorial Fellow
Melbourne School Of Population And Global Health
risk factors
colorectal cancer
epidemiology
prevention
screening
bowel cancer
genomics
early detection
Lynch syndrome
Mark Jenkins's Profile Picture
Prof

Mark Jenkins

 
Division
Medicine, Dentistry And Health Sciences
 
Primary Interest
Precision prevention and early detection of bowel cancer
Mark Jenkins's Profile Picture
Prof

Mark Jenkins

 

Professor Jenkins is the Director of the Centre for Epidemiology & Biostatistics, School of Population & Global Health, and he is a Group leader in the Centre for Cancer Research. He is an epidemiologist with 20 years' experience in the design, conduct, and analysis of studies examining the role of genetic and environmental causes of cancer, and the prevention and early detection of colorectal cancer, particularly in screening participation.

He is the Chief Investigator of the NHMRC Centre for Research Excellence: Reducing the Burden of Colorectal Cancer by Optimising Screening. He is Principal Investigator of the NIH funded international collaboration: Colon Cancer Family Registry Cohort, and is the Chief Investigator of the Worldwide study of Cancer Risks for Lynch syndrome. He currently teaches at postgraduate level, a course in Genetic Epidemiology. He is a member of the Clinical Advisory Group for the National Bowel Cancer Screening Program.

Projects

Displaying the 57 most recent projects by Mark Jenkins.

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Script: An Rct Of Genomic-Based Stratified Colorectal Cancer Screening In Primary Care.

2020 - 2023
Active
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The Sita Trial (Should I Take Aspirin?): An Rct Of A Decision Aid To Support Informed Choices About Taking Aspirin To Prevent Cancer And Other Chronic Disease.

2020 - 2022
Active
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A Randomised Controlled Trial Of Patient Narrative Sms Messaging In General Practice To Increase Participation In The National Bowel Cancer Screening Program In Victoria.

2020 - 2022
Active
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Why Does Colonoscopy Fail To Prevent Colon Cancer In People With Lynch Syndrome?

2020 - 2022
Active
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Heritable Methylation Marks Associated With Colorectal Cancer Risk

2019 - 2020
Active
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Colon Cancer Family Registry Cohort

2018 - 2023
Active
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Colon Cancer Family Registry Cohort

2018 - 2023
Active
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A Worldwide Study Of Cancer Risk For Lynch Syndrome

2017 - 2021
Active
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Utility Of Genetic Screening For Colorectal Cancer Risk Assessment

Bowel cancer can be prevented by regular screening, however screening is not targeted to those most at risk and only 30% take up the offer. ..

2017 - 2021
Active
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Licence And Services Agreement Between UOM And Genetic Technologies Limited

2016 - 2018
Completed
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The Crisp Trial: A Phase Ii Rct Of A Risk Assessment Tool For Stratified Colorectal Cancer Screening In Primary Care

2016 - 2020
Active
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Worldwide Study Of Cancer Risks For Lynch Syndrome

2016 - 2017
Completed
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Precision Public Health For Major Cancers - Novel Approaches To Building The Genetic, Epigenetic And Lifestyle Knowledge Base For Assessing Risk And Prognosis

The Program of research seeks to increase our understanding of cancer risk. We will use our large collections of population and family-based..

2015 - 2019
Completed
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Precision Public Health For Major Cancers - Novel Approaches To Building The Genetic, Epigenetic And Lifestyle Knowledge Base For Assessing Risk And Prognosis

The Program of research seeks to increase our understanding of cancer risk. We will use our large collections of population and family-based..

2015 - 2019
Completed
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Precision Public Health For Major Cancers - Novel Approaches To Building The Genetic, Epigenetic And Lifestyle Knowledge Base For Assessing Risk And Prognosis

The Program of research seeks to increase our understanding of cancer risk. We will use our large collections of population and family-based..

2015 - 2018
Completed
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Integrating Personalised Genomics Into Risk Stratification Models Of Population Screening For Cancer

2014 - 2016
Completed
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Predictors Of Metachronous Colorectal Neoplasms

2014 - 2016
Completed
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Early Onset Colorectal Cancer

There has been a steady increase since 2002, in the age-standardised incidence of CRC in males under 45 years in Australia, contrasting with..

2014 - 2014
Completed
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What Is The Risk Of Cancer For Mutation Carriers?

People with the genetic Lynch syndrome are more likely to get cancer but we cannot accurately predict who will get cancer and when. Doctors ..

2014 - 2016
Completed
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How Effective Is Bowel Cancer Screening And Who Uses It?

About 14,000 cases of bowel cancer occur annually in Australia despite the availability of life-saving screening. Most people do not receive..

2014 - 2016
Completed
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Colon Cancer Family Registry Cohort

2013 - 2019
Completed
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Colon Cancer Family Registry Cohort

2013 - 2018
Completed
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Centre Of Research Excellence For Reducing The Burden Of Colorectal Cancer By Optimising Screening:Evidence Of Clinical Practice

Bowel cancer, the second most diagnosed and cause of cancer death is preventable. Low risk people need no screening or just inexpensive feca..

2012 - 2017
Completed
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Centre Of Research Excellence For Reducing The Burden Of Colorectal Cancer By Optimising Screening:Evidence Of Clinical Practice

Bowel cancer, the second most diagnosed and cause of cancer death is preventable. Low risk people need no screening or just inexpensive feca..

2012 - 2017
Completed
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Trandisciplinary Studies Of Genetic Variation In Colorectal Cancer

2012 - 2013
Completed
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Development Of A Comprehensive Model For Colorectal Cancer Risk Prediction

2012 - 2015
Completed
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Comprehenisve Model For Colorectal Cancer Risk

I am a genetic epidemiologist focused on bowel cancer risk. I will develop a comprehensive model to estimate individual cancer risk by study..

2012 - 2016
Completed
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Impact Of Screening On Colorectal Cancer Incidence And Mortality For Unaffected Young People At Potentially High-Risk Due To Family History Of The Disease.

2012 - 2012
Completed
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Development Of A Comprehensive Model For Colorectal Cancer Risk Prediction

2011 - 2016
Completed
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Risk Factors Of Early-Onset Colorectal Cancer

2011 - 2016
Completed
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Information Theoretic Approaches To Optimise Genome Wide Association Studies With Application To Continuous And Discrete Traits

This project aims to develop new mathematical methods to find genetic associations from new genome-wide studies of colorectal cancer and bre..

2011 - 2014
Completed
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Non-Steroidal Anti-Inflammatory Drugs And Colorectal Cancer Risk For Mismatch Repair Gene Mutation Carriers

2011 - 2016
Completed
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Risk Factors Of Early-Onset Colorectal Cancer

2011 - 2012
Completed
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Collaborative Australian Renal Cell Carcinoma Eipdemiology Study Cares

The objective of this project is to increase our knowledge of the causes of renal cell carcinoma, a relatively common, yet understudied, can..

2011 - 2014
Completed
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Environmental Modifiers Of Endometrial Cancer Risks For Carriers Of Germline Mutations In Dna Mismatch Repair Gene

2010
Active
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Design And Analysis Of 2nd Stage Gwas Study Using Next Generation Sequence Technology

2010 - 2012
Completed
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Trandisciplinary Studies Of Genetic Variation In Colorectal Cancer

2010 - 2012
Completed
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Studies Into Gynaecological Cancers Associated With The Syndrome: Hereditary Nonpolyposis Colon Cancer

2010 - 2013
Completed
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Discovering New Genes For Bowel Cancer

Our aim is to discover new genes that greatly increase bowel cancer risk. If we can identify these carriers we may be able to prevent them g..

2010 - 2013
Completed
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What Do People In Mutation-Carrying Families Understand About Bowel Cancer Gene Testing, Personal Risk And Prevention Behaviours?

2009 - 2013
Completed
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The Familial Colorectal Neoplasia Collaborative Group

2009 - 2011
Completed
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Translational Research To Better Use Genetic Testing To Reduce The Morbidity And Mortality Of Breast Cancer In Victoria

2009 - 2013
Completed
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Translational Research To Better Use Genetic Testing To Reduce The Morbidity And Mortality Of Breast Cancer In Victoria

2009 - 2013
Completed
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How Do Your Genes Affect Your Risk Of Melanoma, And What Can You Do About It?

Excessive sunlight can cause melanoma, a serious type of skin cancer. However, there are other factors including a person's genetic make-up ..

2009 - 2010
Completed
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Markers Of Inflammation And Prostate Cancer Risk

It has been proposed that inflammation plays a major role in prostate cancer risk. We are well placed to test this hypothesis following up e..

2008 - 2011
Completed
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Do Different Types Of Bowel Cancer Have Different Risk Factors?

Colorectal cancer is Australia's most common cancer. It actually has several subtypes that probably have different causes and which may resp..

2008 - 2011
Completed
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How Can The Risk Of Breast Cancer Be Reduced In Those With A Strong Family History Of The Disease?

Having a strong family history for breast cancer is one of the most important risk factors for the disease. Two major genes, BRCA1 and BRCA2..

2007 - 2009
Completed
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What Are The Breast Cancer Risks For An Australian Women Who Carries A Mutation In The Brca1 Or Brca2 Genes?

About 10 years ago two genes, called BRCA1 and BRCA2, were discovered. The normal function of these genes is to prevent breast and other can..

2007 - 2009
Completed
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Studies Into Gynaecological Cancers Associated With The Syndrome: Hereditary Nonpolyposis Colon Cancer

2007 - 2009
Completed
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Mutations In Steroid Hormone Metabolism Genes And Risk Of Breast Cancer

Completed
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Data Use For Candidate Gene Study Using Colon Cfr Population-Based And Clinic-Based Cases, Controls And Families

Completed
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Risk Factors For Chronic Respiratory Diseases In Middle Age: 36-Year Follow Up Of The Tasmanian Asthma Study

This project will improve our understanding of the causes of chronic respiratory diseases (CRDs) in adults. CRDs are clearly a major public ..

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Genetic Modifiers Of Environmental Risk Factors For Longitudinal Changes In Asthma

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Mutations In Steroid Hormone Metabolism Genes And Risk Of Breast Cancer

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Modeling Environmental And Genetic Modifiers Of Mismatch Repair Gene Mutations Using Family Data

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"Germline Mutations In Mismatch Repair Genes: Prevalence, Risk Of Cancer, And Environmental Modifiers Of Risk."

Aims: 1. Develop a model that will predict who has a mutation in a group of genes that cause cancer 2. Estimate risk of cancer in people who..

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Risk Factors, Screening, Prophylaxis And Outcomes In Individuals From Breast Cancer Families: Kconfab Follow-Up Study

Having a strong family history of breast cancer is one of the most important risk factors for the disease. Two major genes, BRCA1 and BRCA2,..

57

Projects

Project Types

44

Research Grant

13

Research Contracts

Scholarly Works

Displaying the 432 most recent scholarly works by Mark Jenkins.

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Development and external validation study of a melanoma risk prediction model incorporating clinically assessed naevi and solar lentigines

K Vuong, BK Armstrong, M Drummond, JL Hopper, JH Barrett, JR Davies, DT Bishop, J Newton-Bishop, JF Aitken, GG Giles, H Schmid, MA Jenkins, GJ Mann, K McGeechan, AE Cust

Journal article  |  2020  |  British Journal of Dermatology

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Association of body mass index with colorectal cancer risk by genome-wide variants.

Peter T Campbell, Yi Lin, Stephanie A Bien, Jane C Figueiredo, Tabitha A Harrison, Mark J Guinter, Sonja I Berndt, Hermann Brenner, Andrew T Chan, Jenny Chang-Claude, Steven J Gallinger, Susan M Gapstur, Graham G Giles, Edward Giovannucci, Stephen B Gruber, Marc Gunter, Michael Hoffmeister, Eric J Jacobs, Mark A Jenkins, Loic Le Marchand, et al.

Journal article  |  2020  |  JNCI: Journal of the National Cancer Institute

BACKGROUND: Body mass index (BMI) is a complex phenotype that may interact with genetic variants to influence colorectal cancer ri..

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Potential impact of family history-based screening guidelines on the detection of early-onset colorectal cancer

Samir Gupta, Balambal Bharti, Dennis J Ahnen, Daniel D Buchanan, Iona C Cheng, Michelle Cotterchio, Jane C Figueiredo, Steven J Gallinger, Robert W Haile, Mark A Jenkins, Noralane M Lindor, Finlay A Macrae, Loic Le Marchand, Polly A Newcomb, Stephen N Thibodeau, Aung Ko Win, Maria Elena Martinez

Journal article  |  2020  |  Cancer

BACKGROUND: Initiating screening at an earlier age based on cancer family history is one of the primary recommended strategies for..

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Cumulative Burden of Colorectal Cancer Associated Genetic Variants Is More Strongly Associated With Early-Onset vs Late-Onset Cancer

Alexi N Archambault, Yu-Ru Su, Jihyoun Jeon, Minta Thomas, Yi Lin, David V Conti, Aung Ko Win, Lori C Sakoda, Iris Lansdorp-Vogelaar, Elisabeth FP Peterse, Ann G Zauber, David Duggan, Andreana N Holowatyj, Jeroen R Huyghe, Hermann Brenner, Michelle Cotterchio, Stephane Bezieau, Stephanie L Schmit, Christopher K Edlund, Melissa C Southey, et al.

Journal article  |  2020  |  Gastroenterology

BACKGROUND & AIMS: Early-onset colorectal cancer (CRC, in persons younger than 50 years old) is increasing in incidence; yet, in t..

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Circulating Levels of Insulin-like Growth Factor 1 and Insulin-like Growth Factor Binding Protein 3 Associate With Risk of Colorectal Cancer Based on Serologic and Mendelian Randomization Analyses

Neil Murphy, Robert Carreras-Torres, Mingyang Song, Andrew T Chan, Richard M Martin, Nikos Papadimitriou, Niki Dimou, Konstantinos K Tsilidis, Barbara Banbury, Kathryn E Bradbury, Jelena Besevic, Sabina Rinaldi, Elio Riboli, Amanda J Cross, Ruth C Travis, Claudia Agnoli, Demetrius Albanes, Sonja I Berndt, Stephane Bezieau, D Timothy Bishop, et al.

Journal article  |  2020  |  Gastroenterology

BACKGROUND & AIMS: Human studies examining associations between circulating levels of insulin-like growth factor 1 (IGF1) and insu..

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Mendelian Randomization of Circulating Polyunsaturated Fatty Acids and Colorectal Cancer Risk.

Nikhil K Khankari, Barbara L Banbury, Maria C Borges, Philip Haycock, Demetrius Albanes, Volker Arndt, Sonja I Berndt, Stéphane Bézieau, Hermann Brenner, Peter T Campbell, Graham Casey, Andrew T Chan, Jenny Chang-Claude, David V Conti, Michelle Cotterchio, Dallas R English, Jane C Figueiredo, Graham G Giles, Edward L Giovannucci, Marc J Gunter, et al.

Journal article  |  2020  |  Cancer Epidemiology Biomarkers & Prevention

BACKGROUND: Results from epidemiologic studies examining polyunsaturated fatty acids (PUFA) and colorectal cancer risk are inconsi..

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Utility of the methylated SEPT9 test for the early detection of colorectal cancer: a systematic review and meta-analysis of diagnostic test accuracy

Rohit Hariharan, Mark Jenkins

Journal article  |  2020  |  BMJ Open Gastroenterology

Background: Circulating tumour DNA from colorectal cancer (CRC) is a biomarker for early detection of the disease and therefore po..

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Functional informed genome-wide interaction analysis of body mass index, diabetes and colorectal cancer risk

Zhiyu Xia, Yu-Ru Su, Paneen Petersen, Lihong Qi, Andre E Kim, Jane C Figueiredo, Yi Lin, Hongmei Nan, Lori C Sakoda, Demetrius Albanes, Sonja I Berndt, Stephane Bezieau, Stephanie Bien, Daniel D Buchanan, Graham Casey, Andrew T Chan, David V Conti, David A Drew, Steven J Gallinger, W James Gauderman, et al.

Journal article  |  2020  |  Cancer Medicine

BACKGROUND: Body mass index (BMI) and diabetes are established risk factors for colorectal cancer (CRC), likely through perturbati..

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A New Comprehensive Colorectal Cancer Risk Prediction Model Incorporating Family History, Personal Characteristics, and Environmental Factors

Yingye Zheng, Xinwei Hua, Aung K Win, Robert J MacInnis, Steven Gallinger, Loic Le Marchand, Noralane M Lindor, John A Baron, John L Hopper, James G Dowty, Antonis C Antoniou, Jiayin Zheng, Mark A Jenkins, Polly A Newcomb

Journal article  |  2020  |  Cancer Epidemiology Biomarkers & Prevention

PURPOSE: Reducing colorectal cancer incidence and mortality through early detection would improve efficacy if targeted. We develop..

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Do the risks of Lynch syndrome-related cancers depend on the parent of origin of the mutation?

Shimelis Dejene Gemechu, Christine M van Vliet, Aung Ko Win, Jane C Figueiredo, Loic Le Marchand, Steven Gallinger, Polly A Newcomb, John L Hopper, Noralane M Lindor, Mark A Jenkins, James G Dowty

Journal article  |  2020  |  Familial Cancer

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Association Between Molecular Subtypes of Colorectal Tumors and Patient Survival, Based on Pooled Analysis of 7 International Studies.

Amanda I Phipps, Elizabeth Alwers, Tabitha Harrison, Barbara Banbury, Hermann Brenner, Peter T Campbell, Jenny Chang-Claude, Daniel Buchanan, Andrew T Chan, Alton B Farris, Jane C Figueiredo, Steven Gallinger, Graham G Giles, Mark Jenkins, Roger L Milne, Polly A Newcomb, Martha L Slattery, Mingyang Song, Shuji Ogino, Syed H Zaidi, et al.

Journal article  |  2020  |  Gastroenterology

BACKGROUND AND AIMS: The heterogeneity among colorectal tumors is probably due to differences in developmental pathways and might ..

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Physical activity and risks of breast and colorectal cancer: a Mendelian randomisation analysis.

Nikos Papadimitriou, Niki Dimou, Konstantinos K Tsilidis, Barbara Banbury, Richard M Martin, Sarah J Lewis, Nabila Kazmi, Timothy M Robinson, Demetrius Albanes, Krasimira Aleksandrova, Sonja I Berndt, D Timothy Bishop, Hermann Brenner, Daniel D Buchanan, Bas Bueno-de-Mesquita, Peter T Campbell, Sergi Castellví-Bel, Andrew T Chan, Jenny Chang-Claude, Merete Ellingjord-Dale, et al.

Journal article  |  2020  |  Nature Communications

Physical activity has been associated with lower risks of breast and colorectal cancer in epidemiological studies; however, it is ..

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DNA repair and cancer in colon and rectum: Novel players in genetic susceptibility

Barbara Pardini, Alda Corrado, Elisa Paolicchi, Giovanni Cugliari, Sonja Berndt, Stephane Bezieau, Stephanie A Bien, Hermann Brenner, Bette J Caan, Peter T Campbell, Graham Casey, Andrew T Chan, Jenny Chang-Claude, Michelle Cotterchio, Manish Gala, Steven J Gallinger, Robert W Haile, Tabitha A Harrison, Richard B Hayes, Michael Hoffmeister, et al.

Journal article  |  2020  |  International Journal of Cancer

Interindividual differences in DNA repair systems may play a role in modulating the individual risk of developing colorectal cance..

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Fine-mapping of 150 breast cancer risk regions identifies 191 likely target genes

Laura Fachal, Hugues Aschard, Jonathan Beesley, Daniel R Barnes, Jamie Allen, Siddhartha Kar, Karen A Pooley, Joe Dennis, Kyriaki Michailidou, Constance Turman, Penny Soucy, Audrey Lemacon, Michael Lush, Jonathan P Tyrer, Maya Ghoussaini, Mahdi Moradi Marjaneh, Xia Jiang, Simona Agata, Kristiina Aittomaki, M Rosario Alonso, et al.

Journal article  |  2020  |  Nature Genetics

Genome-wide association studies have identified breast cancer risk variants in over 150 genomic regions, but the mechanisms underl..

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Cost-Effectiveness of Personalized Screening for Colorectal Cancer Based on Polygenic Risk and Family History

Dayna R Cenin, Steffie K Naber, Anne C de Weerdt, Mark A Jenkins, David B Preen, C Ee Hooi, Peter C O'Leary, Iris Lansdorp-Vogelaar

Journal article  |  2020  |  Cancer Epidemiology Biomarkers & Prevention

BACKGROUND: There is growing evidence for personalizing colorectal cancer screening based on risk factors. We compared the cost-ef..

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Childhood pneumonia, pleurisy and lung function: a cohort study from the first to sixth decade of life

Jennifer L Perret, Caroline J Lodge, Adrian J Lowe, David P Johns, Bruce R Thompson, Dinh S Bui, Lyle C Gurrin, Melanie C Matheson, Christine F McDonald, Richard Wood-Baker, Cecilie Svanes, Paul S Thomas, Graham G Giles, Anne B Chang, Michael J Abramson, E Haydn Walters, Shyamali C Dharmage, Heather Gibson, Bryan Gandevia, Harold Silverstone, et al.

Journal article  |  2020  |  Thorax

INTRODUCTION: Adult spirometry following community-acquired childhood pneumonia has variably been reported as showing obstructive ..

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Cancer risks by gene, age, and gender in 6350 carriers of pathogenic mismatch repair variants: findings from the Prospective Lynch Syndrome Database

Mev Dominguez-Valentin, Julian R Sampson, Toni T Seppala, Sanne W ten Broeke, John-Paul Plazzer, Sigve Nakken, Christoph Engel, Stefan Aretz, Mark A Jenkins, Lone Sunde, Inge Bernstein, Gabriel Capella, Francesc Balaguer, Huw Thomas, D Gareth Evans, John Burn, Marc Greenblatt, Eivind Hovig, Wouter H de Vos Tot Nederveen Cappel, Rolf H Sijmons, et al.

Journal article  |  2020  |  Genetics in Medicine

PURPOSE: Pathogenic variants affecting MLH1, MSH2, MSH6, and PMS2 cause Lynch syndrome and result in different but imprecisely kno..

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Modifiable pathways for colorectal cancer: a mendelian randomisation analysis

Alex J Cornish, Philip J Law, Maria Timofeeva, Kimmo Palin, Susan M Farrington, Claire Palles, Mark A Jenkins, Graham Casey, Hermann Brenner, Jenny Chang-Claude, Michael Hoffmeister, Iva Kirac, Tim Maughan, Stefanie Brezina, Andrea Gsur, Jeremy P Cheadle, Lauri A Aaltonen, Ian Tomlinson, Malcolm G Dunlop, Richard S Houlston

Journal article  |  2020  |  The Lancet Gastroenterology & Hepatology

BACKGROUND: Epidemiological studies have linked lifestyle, cardiometabolic, reproductive, developmental, and inflammatory factors ..

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Systematic meta-analyses, field synopsis and global assessment of the evidence of genetic association studies in colorectal cancer.

Zahra Montazeri, Xue Li, Christine Nyiraneza, Xiangyu Ma, Maria Timofeeva, Victoria Svinti, Xiangrui Meng, Yazhou He, Yacong Bo, Samuel Morgan, Sergi Castellví-Bel, Clara Ruiz-Ponte, Ceres Fernández-Rozadilla, Ángel Carracedo, Antoni Castells, Timothy Bishop, Daniel Buchanan, Mark A Jenkins, Temitope O Keku, Annika Lindblom, et al.

Journal article  |  2019  |  Gut

OBJECTIVE: To provide an understanding of the role of common genetic variations in colorectal cancer (CRC) risk, we report an upda..

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Development and validation of a targeted gene sequencing panel for application to disparate cancers

Mark J McCabe, Marie-Emilie A Gauthier, Chia-Ling Chan, Tanya J Thompson, Sunita MC De Sousa, Clare Puttick, John P Grady, Velimir Gayevskiy, Jiang Tao, Kevin Ying, Arcadi Cipponi, Niantao Deng, Alex Swarbrick, Melissa L Thomas, undefined kConFab, Reginald V Lord, Amber L Johns, Maija Kohonen-Corish, Sandra A O'Toole, Jonathan Clark, et al.

Journal article  |  2019  |  Scientific Reports

Next generation sequencing has revolutionised genomic studies of cancer, having facilitated the development of precision oncology ..

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Interval breast cancer risk associations with breast density, family history and breast tissue aging

Tuong L Nguyen, Shuai Li, Gillian S Dite, Ye K Aung, Christopher F Evans, Ho N Trinh, Laura Baglietto, Jennifer Stone, Yun-Mi Song, Joohon Sung, Dallas R English, Mark A Jenkins, Pierre-Antoine Dugue, Roger L Milne, Melissa C Southey, Graham G Giles, Malcolm C Pike, John L Hopper

Journal article  |  2019  |  International Journal of Cancer

Interval breast cancers (those diagnosed between recommended mammography screens) generally have poorer outcomes and are more comm..

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Type 2 diabetes mellitus, blood cholesterol, triglyceride and colorectal cancer risk in Lynch syndrome

S Ghazaleh Dashti, Wing Yan Li, Daniel D Buchanan, Mark Clendenning, Christophe Rosty, Ingrid M Winship, Finlay A Macrae, Graham G Giles, Sheetal Hardikar, Xinwei Hua, Stephen N Thibodeau, Jane C Figueiredo, Graham Casey, Robert W Haile, Steven Gallinger, Loic Le Marchand, Polly A Newcomb, John D Potter, Noralane M Lindor, John L Hopper, et al.

Journal article  |  2019  |  British Journal of Cancer

BACKGROUND: Type 2 diabetes mellitus and high total cholesterol and triglycerides are known to be associated with increased colore..

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The FANCM:p.Arg658* truncating variant is associated with risk of triple-negative breast cancer

Gisella Figlioli, Massimo Bogliolo, Irene Catucci, Laura Caleca, Sandra Viz Lasheras, Roser Pujol, Johanna Kiiski, Taru A Muranen, Daniel R Barnes, Joe Dennis, Kyriaki Michailidou, Manjeet K Bolla, Goska Leslie, Cora M Aalfs, Muriel A Adank, Julian Adlard, Simona Agata, Karen Cadoo, Bjarni A Agnarsson, Thomas Ahearn, et al.

Journal article  |  2019  |  npj Breast Cancer

Breast cancer is a common disease partially caused by genetic risk factors. Germline pathogenic variants in DNA repair genes BRCA1..

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Ability of known susceptibility SNPs to predict colorectal cancer risk for persons with and without a family history

Mark A Jenkins, Aung K Win, James G Dowty, Robert J MacInnis, Enes Makalic, Daniel F Schmidt, Gillian S Dite, Mirosl Kapuscinski, Mark Clendenning, Christophe Rosty, Ingrid M Winship, Jon D Emery, Sibel Saya, Finlay A Macrae, Dennis J Ahnen, David Duggan, Jane C Figueiredo, Noralane M Lindor, Robert W Haile, John D Potter, et al.

Journal article  |  2019  |  Familial Cancer

Before SNP-based risk can be incorporated in colorectal cancer (CRC) screening, the ability of these SNPs to estimate CRC risk for..

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Associations of pigmentary and naevus phenotype with melanoma risk in two populations with comparable ancestry but contrasting levels of ambient sun exposure

AE Cust, M Drummond, DT Bishop, L Azizi, H Schmid, MA Jenkins, JL Hopper, BK Armstrong, JF Aitken, RF Kefford, GG Giles, F Demenais, AM Goldstein, JH Barrett, PA Kanetsky, DE Elder, GJ Mann, JA Newton-Bishop

Journal article  |  2019  |  Journal of the European Academy of Dermatology and Venereology

BACKGROUND: People at high risk of developing melanoma are usually identified by pigmentary and naevus phenotypes. OBJECTIVE: We e..

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Smoking is associated with risks of molecular subtypes of colorectal cancer

Xiaoliang Wang, Efrat Amitay, Barbara L Banbury, Hermann Brenner, Daniel D Buchanan, Peter T Campbell, Jenny Chang-Claude, Steven J Gallinger, Graham G Giles, Tabitha A Harrison, John L Hopper, Mark A Jenkins, Yi Lin, Reiko Nishihara, Polly A Newcomb, Shuji Ogino, Lori C Sakoda, Robert E Schoen, Martha L Slattery, Steven N Thibodeau, et al.

Conference Proceedings  |  2019  |  Epidemiology

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Risks of Colorectal Cancer and Cancer-Related Mortality in Familial Colorectal Cancer Type X and Lynch Syndrome Families

Yun-Hee Choi, Lajmi Lakhal-Chaieb, Agnieszka Krol, Bing Yu, Daniel Buchanan, Dennis Ahnen, Loic Le Marchand, Polly A Newcomb, Aung Ko Win, Mark Jenkins, Noralane M Lindor, Laurent Briollais

Journal article  |  2019  |  JNCI: Journal of the National Cancer Institute

Background: The risk of cancers is well characterized in Lynch syndrome (LS) families but has been less studied in familial colore..

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Cancer screening in Australia: future directions in melanoma, Lynch syndrome, and liver, lung and prostate cancers

Marianne F Weber, Henry M Marshall, Nicole Rankin, Stephen Duffy, Kwun M Fong, Kate Dunlop, Lauren Humphreys, Amelia K Smit, Anne E Cust, Natalie Taylor, Gillian Mitchell, Yoon-Jung Kang, Kathy Tucker, Mark Jenkins, Finlay Macrae, Ian Lockart, Mark Danta, Bruce K Armstrong, Megan Howe

Journal article  |  2019  |  Public Health Research & Practice

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Genetic variant predictors of gene expression provide new insight into risk of colorectal cancer (vol 138, pg 307, 2019)

Stephanie A Bien, Yu-Ru Su, David V Conti, Tabitha A Harrison, Conghui Qu, Xingyi Guo, Yingchang Lu, Demetrius Albanes, Paul L Auer, Barbara L Banbury, Sonja I Berndt, Stephane Bezieau, Hermann Brenner, Daniel D Buchanan, Bette J Caan, Peter T Campbell, Christopher S Carlson, Andrew T Chan, Jenny Chang-Claude, Sai Chen, et al.

Journal article  |  2019  |  Human Genetics

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Tumor mutational signatures in sebaceous skin lesions from individuals with Lynch syndrome

Peter Georgeson, Michael D Walsh, Mark Clendenning, Simin Daneshvar, Bernard J Pope, Khalid Mahmood, Jihoon E Joo, Harindra Jayasekara, Mark A Jenkins, Ingrid M Winship, Daniel D Buchanan

Journal article  |  2019  |  Molecular Genetics & Genomic Medicine

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Identification of circulating protein biomarkers for colorectal cancer risk: A genetic instrument analysis

Xiang Shu, Xiao-ou Shu, Jirong Long, Qiuyin Cai, Conghui Qu, Stephanie L Schmit, Chenxu Qu, Sonja I Berndt, Peter T Campbell, Andrew T Chan, Graham G Giles, Andrea Gsur, Michael Hoffmeister, Mark A Jenkins, Sanford D Markowitz, Li Li, Gad Rennert, Kenneth Offit, David Conti, Annika Lindblom, et al.

Conference Proceedings  |  2019  |  Epidemiology

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Global trends in colorectal cancer mortality: projections to the year 2035

Marzieh Araghi, Isabelle Soerjomataram, Mark Jenkins, James Brierley, Eva Morris, Freddie Bray, Melina Arnold

Journal article  |  2019  |  International Journal of Cancer

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Loss of Independence After Operative Management of Femoral Neck Fractures

Emil H Schemitsch, Sheila Sprague, Martin J Heetveld, Sofia Bzovsky, Diane Heels-Ansdell, Qi Zhou, Marc Swiontkowski, Mohit Bhandari, M Bhandari, M Swiontkowski, PJ Devereaux, Gordon Guyatt, MJ Heetveld, Kyle Jeray, Susan Liew, Martin Richardson, EH Schemitsch, Lehana Thabane, Paul Tornetta, Stephen D Walter, et al.

Journal article  |  2019  |  Journal of Orthopaedic Trauma

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Mendelian randomization analysis of C-reactive protein on colorectal cancer risk

Xiaoliang Wang, James Y Dai, Demetrius Albanes, Volker Arndt, Sonja I Berndt, Stephane Bezieau, Hermann Brenner, Daniel D Buchanan, Katja Butterbach, Bette Caan, Graham Casey, Peter T Campbell, Andrew T Chan, Zhengyi Chen, Jenny Chang-Claude, Michelle Cotterchio, Douglas F Easton, Graham G Giles, Edward Giovannucci, William M Grady, et al.

Journal article  |  2019  |  International Journal of Epidemiology

Background: Chronic inflammation is a risk factor for colorectal cancer (CRC). Circulating C-reactive protein (CRP) is also modera..

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Differences in MSI phenotype between cancer types using a new PCR-based pan-cancer biomarker panel.

Jeff Bacher, Eshwar Udho, Doug Storts, Richard Halberg, Steven Gallinger, Mark A Jenkins, Noralane M Lindor

Conference Proceedings  |  2019  |  Journal of Clinical Oncology

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Association analyses identify 31 new risk loci for colorectal cancer susceptibility

Philip J Law, Maria Timofeeva, Ceres Fernandez-Rozadilla, Aria Timofeeva, Peter Broderick, James Studd, Juan Fernandez-Tajes, Susan Farrington, Victoria Svinti, Claire Palles, Giulia Orlando, Amit Sud, Amy Holroyd, Steven Penegar, Evropi Theodoratou, Peter Vaughan-Shaw, Harry Campbell, Lina Zgaga, Caroline Hayward, Archie Campbell, et al.

Journal article  |  2019  |  Nature Communications

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Assessing the ProMCol classifier as a prognostic marker for non-metastatic colorectal cancer within the Melbourne Collaborative Cohort Study

Jihoon E Joo, Harindra Jayasekara, Ee Ming Wong, Mark Clendenning, Christophe Rosty, Ingrid M Winship, Mark A Jenkins, John L Hopper, Dallas R English, Roger L Milne, Graham G Giles, Melissa C Southey, Daniel D Buchanan

Journal article  |  2019  |  Gut

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Meeting report from the joint IARC-NCI international cancer seminar series: a focus on colorectal cancer

MJ Gunter, S Alhomoud, M Arnold, H Brenner, J Burn, G Casey, AT Chan, AJ Cross, E Giovannucci, R Hoover, R Houlston, M Jenkins, P Laurent-Puig, U Peters, D Ransohoff, E Riboli, R Sinha, ZK Stadler, P Brennan, SJ Chanock

Journal article  |  2019  |  Annals of Oncology

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Meeting report from the joint IARC-NCI international cancer seminar series: a focus on colorectal cancer.

MJ Gunter, S Alhomoud, M Arnold, H Brenner, J Burn, G Casey, AT Chan, AJ Cross, E Giovannucci, R Hoover, R Houlston, M Jenkins, P Laurent-Puig, U Peters, D Ransohoff, E Riboli, R Sinha, ZK Stadler, P Brennan, SJ Chanock

Journal article  |  2019  |  Annals of oncology : official journal of the European Society for Medical Oncology

Despite significant progress in our understanding of the etiology, biology and genetics of colorectal cancer, as well as important..

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Genetic variant predictors of gene expression provide new insight into risk of colorectal cancer

Stephanie A Bien, Yu-Ru Su, David V Conti, Tabitha A Harrison, Conghui Qu, Xingyi Guo, Yingchang Lu, Demetrius Albanes, Paul L Auer, Barbara L Banbury, Sonja I Berndt, Stephane Bezieau, Hermann Brenner, Daniel D Buchanan, Bette J Caan, Peter T Campbell, Christopher S Carlson, Andrew T Chan, Jenny Chang-Claude, Sai Chen, et al.

Journal article  |  2019  |  Human Genetics

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Large-Scale Genome-Wide Association Study of East Asians Identifies Loci Associated With Risk for Colorectal Cancer

Yingchang Lu, Sun-Seog Kweon, Chizu Tanikawa, Wei-Hua Jia, Yong-Bing Xiang, Qiuyin Cai, Chenjie Zeng, Stephanie L Schmit, Aesun Shin, Keitaro Matsuo, Sun Ha Jee, Dong-Hyun Kim, Jeongseon Kim, Wanqing Wen, Jiajun Shi, Xingyi Guo, Bingshan Li, Nan Wang, Ben Zhang, Xinxiang Li, et al.

Journal article  |  2019  |  Gastroenterology

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Cancer Risks for PMS2-Associated Lynch Syndrome (vol 29, pg 2961, 2018)

Sanne W ten Broeke, Heleen M van der Klift, Carli MJ Tops, Stefan Aretz, Inge Bernstein, Daniel D Buchanan, Albert de la Chapelle, Gabriel Capella, Mark Clendenning, Christoph Engel, Steven Gallinger, Encarna Gomez Garcia, Jane C Figueiredo, Robert Haile, Heather L Hampel, Liselotte van Hest, John L Hopper, Nicoline Hoogerbrugge, Magnus von Knebel Doeberitz, Loic Le Marchand, et al.

Journal article  |  2019  |  Journal of Clinical Oncology

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Early-life exposure to sibling modifies the relationship between CD14 polymorphisms and allergic sensitization

Melisa YZ Lau, Shyamali C Dharmage, John A Burgess, Aung K Win, Adrian J Lowe, Caroline J Lodge, Jennifer Perret, Jennie Hui, Paul S Thomas, Graham Giles, Bruce R Thompson, Michael J Abramson, E Haydn Walters, Melanie C Matheson, Katrina J Allen, Geza Benke, James G Dowty, Bircan Erbas, Iain H Feather, Peter A Frith, et al.

Journal article  |  2019  |  Clinical & Experimental Allergy

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Novel Common Genetic Susceptibility Loci for Colorectal Cancer

Stephanie L Schmit, Christopher K Edlund, Fredrick R Schumacher, Jian Gong, Tabitha A Harrison, Jeroen R Huyghe, Chenxu Qu, Marilena Melas, David J Van den Berg, Hansong Wang, Stephanie Tring, Sarah J Plummer, Demetrius Albanes, M Henar Alonso, Christopher I Amos, Kristen Anton, Aaron K Aragaki, Volker Arndt, Elizabeth L Barry, Sonja I Berndt, et al.

Journal article  |  2019  |  JNCI: Journal of the National Cancer Institute

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Shared heritability and functional enrichment across six solid cancers

Xia Jiang, Hilary K Finucane, Fredrick R Schumacher, Stephanie L Schmit, Jonathan P Tyrer, Younghun Han, Kyriaki Michailidou, Corina Lesseur, Karoline B Kuchenbaecker, Joe Dennis, David V Conti, Graham Casey, Mia M Gaudet, Jeroen R Huyghe, Demetrius Albanes, Melinda C Aldrich, Angeline S Andrew, Irene L Andrulis, Hoda Anton-Culver, Antonis C Antoniou, et al.

Journal article  |  2019  |  Nature Communications

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Polygenic Risk Scores for Prediction of Breast Cancer and Breast Cancer Subtypes

Nasim Mavaddat, Kyriaki Michailidou, Joe Dennis, Michael Lush, Laura Fachal, Andrew Lee, Jonathan P Tyrer, Ting-Huei Chen, Qin Wang, Manjeet K Bolla, Xin Yang, Muriel A Adank, Thomas Ahearn, Kristiina Aittomaki, Jamie Allen, Irene L Andrulis, Hoda Anton-Culver, Natalia N Antonenkova, Volker Arndt, Kristan J Aronson, et al.

Journal article  |  2019  |  The American Journal of Human Genetics

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Trends in Colon and Rectal Cancer Incidence in Australia from 1982 to 2014: Analysis of Data on Over 375,000 Cases

Eleonora Feletto, Xue Qin Yu, Jie-Bin Lew, D James B St John, Mark A Jenkins, Finlay A Macrae, Suzanne E Mahady, Karen Canfell

Journal article  |  2019  |  Cancer Epidemiology Biomarkers & Prevention

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Discovery of common and rare genetic risk variants for colorectal cancer

Jeroen R Huyghe, Stephanie A Bien, Tabitha A Harrison, Hyun Min Kang, Sai Chen, Stephanie L Schmit, David V Conti, Conghui Qu, Jihyoun Jeon, Christopher K Edlund, Peyton Greenside, Michael Wainberg, Fredrick R Schumacher, Joshua D Smith, David M Levine, Sarah C Nelson, Nasa A Sinnott-Armstrong, Demetrius Albanes, M Henar Alonso, Kristin Anderson, et al.

Journal article  |  2019  |  Nature Genetics

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Assessment of a European Bladder Cancer Predictive Model for Non-Muscle Invasive Bladder Cancer in an Australian Cohort

Matthew Alberto, Stephanie Demkiw, Jeremy Goad, Mark Jenkins, Genevieve Duggan, Tyler Mow, Lih-Ming Wong

Journal article  |  2019  |  Bladder Cancer

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Predicting interval and screen-detected breast cancers from mammographic density defined by different brightness thresholds

Tuong L Nguyen, Ye K Aung, Shuai Li, Ho Trinh Nhut, Christopher F Evans, Laura Baglietto, Kavitha Krishnan, Gillian S Dite, Jennifer Stone, Dallas R English, Yun-Mi Song, Joohon Sung, Mark A Jenkins, Melissa C Southey, Graham G Giles, John L Hopper

Journal article  |  2018  |  Breast Cancer Research

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Benefits, Harms, and Cost-Effectiveness of Potential Age Extensions to the National Bowel Cancer Screening Program in Australia

Jie-Bin Lew, D James B St John, Finlay A Macrae, Jon D Emery, Hooi C Ee, Mark A Jenkins, Emily He, Paul Grogan, Michael Caruana, Marjolein JE Greuter, Veerle MH Coupe, Karen Canfell

Journal article  |  2018  |  Cancer Epidemiology Biomarkers & Prevention

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Diagnostics for Pleiotropy in Mendelian Randomization Studies: Global and Individual Tests for Direct Effects

James Y Dai, Ulrike Peters, Xiaoyu Wang, Jonathan Kocarnik, Jenny Chang-Claude, Martha L Slattery, Andrew Chan, Mathieu Lemire, Sonja I Berndt, Graham Casey, Mingyang Song, Mark A Jenkins, Hermann Brenner, Aaron P Thrift, Emily White, Li Hsu

Journal article  |  2018  |  American Journal of Epidemiology

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Revised Australian national guidelines for colorectal cancer screening: family history

Mark A Jenkins, Driss Ait Ouakrim, Alex Boussioutas, John L Hopper, Hooi C Ee, Jon D Emery, Finlay A Macrae, Albert Chetcuti, Laura Wuellner, D James B St John

Journal article  |  2018  |  Medical Journal of Australia

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Physical activity and the risk of colorectal cancer in Lynch syndrome

S Ghazaleh Dashti, Aung Ko Win, Sheetal S Hardikar, Stephen E Glombicki, Sheila Mallenahalli, Selvi Thirumurthi, Susan K Peterson, Y Nancy You, Daniel D Buchanan, Jane C Figueiredo, Peter T Campbell, Steven Gallinger, Polly A Newcomb, John D Potter, Noralane M Lindor, Loic Le Marchand, Robert W Haile, John L Hopper, Mark A Jenkins, Karen M Basen-Engquist, et al.

Journal article  |  2018  |  International Journal of Cancer

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Can genetic risk profiling aid risk categorisation for colorectal cancer?

Mark Jenkins

Conference Proceedings  |  2018  |  ASIA-PACIFIC JOURNAL OF CLINICAL ONCOLOGY

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Epidemiology of lynch syndrome

Mark Jenkins

Conference Proceedings  |  2018  |  ASIA-PACIFIC JOURNAL OF CLINICAL ONCOLOGY

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Cancer Risks for PMS2-Associated Lynch Syndrome

Sanne W ten Broeke, Heleen M van der Klift, Carli MJ Tops, Stefan Aretz, Inge Bernstein, Daniel D Buchanan, Albert de la Chapelle, Gabriel Capella, Mark Clendenning, Christoph Engel, Steven Gallinger, Encarna Gomez Garcia, Jane C Figueiredo, Robert Haile, Heather L Hampel, John L Hopper, Nicoline Hoogerbrugge, Magnus von Knebel Doeberitz, Loic Le Marchand, Tom GW Letteboer, et al.

Journal article  |  2018  |  Journal of Clinical Oncology

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Costs and outcomes of Lynch syndrome screening in the Australian colorectal cancer population

Dayna R Cenin, Steffie K Naber, Iris Lansdorp-Vogelaar, Mark A Jenkins, Daniel D Buchanan, David B Preen, Hooi C Ee, Peter O'Leary

Journal article  |  2018  |  Journal of Gastroenterology and Hepatology

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Development of a pan-cancer biomarker panel for improved detection of MSI across all cancer types.

J Bacher, R Halberg, P Ward, E Udho, K Murphy, M Uhr, L Dubeau, J Pettersson, D Storts, S Gallinger, D Buchanan, M Jenkins, N Lindor, J Eshleman

Journal article  |  2018  |  Annals of Oncology

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DNA mismatch repair protein deficient non-neoplastic colonic crypts: a novel indicator of Lynch syndrome

Rish K Pai, Beth Dudley, Eve Karloski, Randall E Brand, Neil O'Callaghan, Christophe Rosty, Daniel D Buchanan, Mark A Jenkins, Stephen N Thibodeau, Amy J French, Noralane M Lindor, Reetesh K Pai

Journal article  |  2018  |  Modern Pathology

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Discussions about predictive genetic testing for Lynch syndrome: the role of health professionals and families in decisions to decline

Anaita Kanga-Parabia, Clara Gaff, Louisa Flander, Mark Jenkins, Louise A Keogh

Journal article  |  2018  |  Familial Cancer

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Sunscreen Use and Melanoma Risk Among Young Australian Adults

Caroline G Watts, Martin Drummond, Chris Goumas, Helen Schmid, Bruce K Armstrong, Joanne F Aitken, Mark A Jenkins, Graham G Giles, John L Hopper, Graham J Mann, Anne E Cust

Journal article  |  2018  |  JAMA Dermatology

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Risk of colorectal cancer for carriers of a germ-line mutation in POLE or POLD1

Daniel D Buchanan, Jenna R Stewart, Mark Clendenning, Christophe Rosty, Khalid Mahmood, Bernard J Pope, Mark A Jenkins, John L Hopper, Melissa C Southey, Finlay A Macrae, Ingrid M Winship, Aung Ko Win

Journal article  |  2018  |  Genet Med

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Family history-based colorectal cancer screening in Australia: A modelling study of the costs, benefits, and harms of different participation scenarios

Mary Dillon, Louisa Flander, Daniel D Buchanan, Finlay A Macrae, Jon D Emery, Ingrid M Winship, Alex Boussioutas, Graham G Giles, John L Hopper, Mark A Jenkins, Driss Ait Ouakrim

Journal article  |  2018  |  PLOS Medicine

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The use of a risk assessment and decision support tool (CRISP) compared with usual care in general practice to increase risk-stratified colorectal cancer screening: study protocol for a randomised controlled trial

Jennifer G Walker, Finlay Macrae, Ingrid Winship, Jasmeen Oberoi, Sibel Saya, Shakira Milton, Adrian Bickerstaffe, James G Dowty, Richard De Abreu Lourenco, Malcolm Clark, Louise Galloway, George Fishman, Fiona M Walter, Louisa Flander, Patty Chondros, Driss Ait Ouakrim, Marie Pirotta, Lyndal Trevena, Mark A Jenkins, Jon D Emery

Journal article  |  2018  |  Trials

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Evaluation of the benefits, harms and cost-effectiveness of potential alternatives to iFOBT testing for colorectal cancer screening in Australia

Jie-Bin Lew, D James B St John, Finlay A Macrae, Jon D Emery, Hooi C Ee, Mark A Jenkins, Emily He, Paul Grogan, Michael Caruana, Diana Sarfati, Marjolein JE Greuter, Veerle MH Coupe, Karen Canfell

Journal article  |  2018  |  International Journal of Cancer

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Interactions between genetic predictors of gene expression and dietary factors associated with risk of colorectal cancer

Paneen S Petersen, Yu-Ru Su, Sonja I Berndt, Stephanie A Bien, Hermann Brenner, Graham Casey, Andrew T Chan, Jenny Chang-Claude, Jane C Figueiredo, Steven J Gallinger, Robert W Haile, Tabitha A Harrison, Michael Hoffmeister, Mark A Jenkins, Amit D Joshi, Sebastien Kury, Loic Le Marchand, Yi Lin, Noralane M Lindor, Polly A Newcomb, et al.

Conference Proceedings  |  2018  |  Epidemiology

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The melanoma genomics managing your risk study: A protocol for a randomized controlled trial evaluating the impact of personal genomic risk information on skin cancer prevention behaviors

Amelia K Smit, Ainsley J Newson, Rachael L Morton, Michael Kimlin, Louise Keogh, Matthew H Law, Judy Kirk, Suzanne Dobbinson, Peter A Kanetsky, Georgina Fenton, Martin Allen, Phyllis Butow, Kate Dunlop, Lyndal Trevena, Serigne Lo, Jacqueline Savard, Hugh Dawkins, Sarah Wordsworth, Mark Jenkins, Graham J Mann, et al.

Journal article  |  2018  |  Contemporary Clinical Trials

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Functionally informed genome-wide interaction analysis of nonsteroidal anti-inflammatory drugs on colorectal cancer risk

Xiaoliang Wang, Yu-Ru Su, Andrew T Chan, Stephanie Bien, Sonja I Bernt, Hermann Brenner, Graham Casey, Jenny Chang-Claude, Steven J Gallinger, Robert W Haile, Tabitha A Harrison, Michael Hoffmeister, Mark A Jenkins, Amit Joshi, Yi Lin, Noralane M Lindor, Loic Le Marchand, Hongmei Nan, Polly A Newcomb, John D Potter, et al.

Conference Proceedings  |  2018  |  Epidemiology

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Genetic variation related to innate immunity and colorectal cancer risk

Jessica Citronberg, Barbara Banbury, Andrew T Chan, Peter T Campbell, Graham Casey, Jenny Chang-Claude, Steven J Gallinger, Tabitha Harrison, Michael Hoffmeister, Mark A Jenkins, Loic Le Marchand, Hongmei Nan, Li Jiao, Robert E Schoen, Hermann Brenner, Emily White, Ulrike Peters, Polly A Newcomb

Conference Proceedings  |  2018  |  Epidemiology

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Genome-wide association study by colorectal carcinoma subtype

Tabitha A Harrison, Yiwen Lu, Chenjie Zeng, Flora Qu, Kristin Anderson, Hermann Brenner, Daniel D Buchanan, Peter T Campbell, Andrew T Chan, Jenny Chang-Claude, Graham G Giles, Bethany Van Guelpen, Michael Hoffmeister, Mark A Jenkins, Noralane M Lindor, Roger L Milne, Polly A Newcomb, Reiko Nishihara, Michael O Woods, Shuji Ogino, et al.

Conference Proceedings  |  2018  |  Epidemiology

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Cancer risk and survival in path_MMR carriers by gene and gender up to 75 years of age: a report from the Prospective Lynch Syndrome Database

Pal Moller, Toni T Seppala, Inge Bernstein, Elke Holinski-Feder, Paulo Sala, D Gareth Evans, Annika Lindblom, Finlay Macrae, Ignacio Blanco, Rolf H Sijmons, Jacqueline Jeffries, Hans FA Vasen, John Burn, Sigve Nakken, Eivind Hovig, Einar Andreas Rodland, Kukatharmini Tharmaratnam, Wouter H de Vos Tot Nederveen Cappel, James Hill, Juul T Wijnen, et al.

Journal article  |  2018  |  Gut

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Mendelian randomisation study of age at menarche and age at menopause and the risk of colorectal cancer

Sonja Neumeyer, Barbara L Banbury, Volker Arndt, Sonja I Berndt, Stephane Bezieau, Stephanie A Bien, Dan D Buchanan, Katja Butterbach, Bette J Caan, Peter T Campbell, Graham Casey, Andrew T Chan, Stephen J Chanock, James Y Dai, Steven Gallinger, Edward L Giovannucci, Graham G Giles, William M Grady, Jochen Hampe, Michael Hoffmeister, et al.

Journal article  |  2018  |  British Journal of Cancer

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'Why don't I need a colonoscopy?' A novel approach to communicating risks and benefits of colorectal cancer screening

Jon D Emery, Marie Pirotta, Finlay Macrae, Jennifer G Walker, Ashleigh Qama, Alex Boussioutas, Mark Jenkins

Journal article  |  2018  |  Australian Journal of General Practice

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A Mixed-Effects Model for Powerful Association Tests in Integrative Functional Genomics

Yu-Ru Su, Chongzhi Di, Stephanie Bien, Licai Huang, Xinyuan Dong, Goncalo Abecasis, Sonja Berndt, Stephane Bezieau, Hermann Brenner, Bette Caan, Graham Casey, Jenny Chang-Claude, Stephen Chanock, Sai Chen, Charles Connolly, Keith Curtis, Jane Figueiredo, Manish Gala, Steven Gallinger, Tabitha Harrison, et al.

Journal article  |  2018  |  The American Journal of Human Genetics

Genome-wide association studies (GWASs) have successfully identified thousands of genetic variants for many complex diseases; howe..

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POTENTIAL IMPACT OF FAMILY HISTORY BASED SCREENING GUIDELINES ON EARLY CANCER DETECTION AMONG INDIVIDUALS AT RISK FOR YOUNG ONSET COLORECTAL CANCER

Samir Gupta, Balambal Bharti, Dennis Ahnen, Polly Newcomb, Mark Jenkins, Aung Ko Win, D Buchanan, Loic La Marchand, Noralane Lindor, Steven Gallinger, Michelle Cotterchio, Robert Haile, Jane Figueiredo, Iona Cheng, Stephen Thibodeau, Maria Elena Martinez

Conference Proceedings  |  2018  |  GASTROENTEROLOGY

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Genetic susceptibility markers for a breast-colorectal cancer phenotype: Exploratory results from genome-wide association studies

Mala Pande, Aron Joon, Abenaa M Brewster, Wei V Chen, John L Hoppers, Cathy Eng, Sanjay Shete, Graham Casey, Fredrick Schumacher, Yi Lin, Tabitha A Harrison, Emily White, Habibul Ahsan, Irene L Andrulis, Alice S Whittemore, Esther M John, Aung Ko Win, Enes Makalic, Daniel F Schmidt, Miroslaw K Kapuscinski, et al.

Journal article  |  2018  |  PLOS ONE

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Cohort Profile: The Colon Cancer Family Registry Cohort (CCFRC)

Mark A Jenkins, Aung Ko Win, Allyson S Templeton, Maggie S Angelakos, Daniel D Buchanan, Michelle Cotterchio, Jane C Figueiredo, Stephen N Thibodeau, John A Baron, John D Potter, John L Hopper, Graham Casey, Steven Gallinger, Loic Le Marchand, Noralane M Lindor, Polly A Newcomb, Robert W Haile

Journal article  |  2018  |  International Journal of Epidemiology

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The CRISP-Q study Communicating the risks and benefits of colorectal cancer screening

Grace Y Kim, Jennifer Walker, Adrian Bickerstaffe, Nadira Hewabandu, Marie Pirotta, Louisa Flander, Mark Jenkins, Jon Emery

Journal article  |  2018  |  Australian Family Physician

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Ability of known susceptibility SNPs to predict colorectal cancer risk for persons with and without a family history

Mark Jenkins, Aung Win, James Dowty, Robert MacInnis, Enes Makalic, Daniel Schmidt, Gillian Dite, Miroslaw Kapuscinski, Mark Clendenning, Christophe Rosty, Ingrid Winship, Jon Emery, Sibel Saya, Finlay Macrae, Dennis Ahnen, David Duggan, Jane Figueiredo, Noralane Lindor, Robert Haile, John Potter, et al.

Journal article  |  2018

ABSTRACT Background A number of single nucleotide polymorphisms (SNPs), which are common inherited genetic variants, have been ide..

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Interaction between polymorphisms in aspirin metabolic pathways, regular aspirin use and colorectal cancer risk: A case-control study in unselected white European populations

Harsh Sheth, Emma Northwood, Cornelia M Ulrich, Dominique Scherer, Faye Elliott, Jennifer H Barrett, David Forman, C Roland Wolf, Gillian Smith, Michael S Jackson, Mauro Santibanez-Koref, Robert Haile, Graham Casey, Mark Jenkins, Aung Ko Win, John L Hopper, Loic Le Marchand, Noralane M Lindor, Stephen N Thibodeau, John D Potter, et al.

Journal article  |  2018  |  PLOS ONE

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Breast Cancer Risk Associations with Digital Mammographic Density by Pixel Brightness Threshold and Mammographic System

Tuong L Nguyen, Yoon-Ho Choi, Ye K Aung, Christopher F Evans, Nhut H Trinh, Shuai Li, Gillian S Dite, Myeong-Seong Kim, Patrick C Brennan, Mark A Jenkins, Joohon Sung, Yun-Mi Song, John L Hopper

Journal article  |  2018  |  Radiology

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Genome-wide association study and meta-analysis in Northern European populations replicate multiple colorectal cancer risk loci

Tomas Tanskanen, Linda van den Berg, Niko Valimaki, Mervi Aavikko, Eivind Ness-Jensen, Kristian Hveem, Yvonne Wettergren, Elinor Bexe Lindskog, Neeme Tonisson, Andres Metspalu, Kaisa Silander, Giulia Orlando, Philip J Law, Sari Tuupanen, Alexandra E Gylfe, Ulrika A Hanninen, Tatiana Cajuso, Johanna Kondelin, Antti-Pekka Sarin, Eero Pukkala, et al.

Journal article  |  2018  |  International Journal of Cancer

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Genomic Characterization of Upper-Tract Urothelial Carcinoma in Patients With Lynch Syndrome

Timothy E Donahue, Aditya Bagrodia, Francois Audenet, Mark TA Donoghue, Eugene K Cha, John P Sfakianos, Dahlia Sperling, Hikmat Al-Ahmadie, Mark Clendenning, Christophe Rosty, Daniel D Buchanan, Mark Jenkins, John Hopper, Ingrid Winship, Allyson S Templeton, Michael F Walsh, Zsofia K Stadler, Gopa Iyer, Barry Taylor, Jonathan Coleman, et al.

Journal article  |  2018  |  JCO Precision Oncology

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Associations of alcohol intake, smoking, physical activity and obesity with survival following colorectal cancer diagnosis by stage, anatomic site and tumor molecular subtype

Harindra Jayasekara, Dallas R English, Andrew Haydon, Allison M Hodge, Brigid M Lynch, Christophe Rosty, Elizabeth J Williamson, Mark Clendenning, Melissa C Southey, Mark A Jenkins, Robin Room, John L Hopper, Roger L Milne, Daniel D Buchanan, Graham G Giles, Robert J MacInnis

Journal article  |  2018  |  International Journal of Cancer

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The International Mismatch Repair Consortium

Mark A Jenkins, Jeanette C Reece, Aung K Win

Book Chapter  |  2018

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Somatic mutations of the coding microsatellites within the beta-2-microglobulin gene in mismatch repair-deficient colorectal cancers and adenomas

Mark Clendenning, Alvin Huang, Harindra Jayasekara, Marie Lorans, Susan Preston, Neil O'Callaghan, Bernard J Pope, Finlay A Macrae, Ingrid M Winship, Roger L Milne, Graham G Giles, Dallas R English, John L Hopper, Aung K Win, Mark A Jenkins, Melissa C Southey, Christophe Rosty, Daniel D Buchanan

Journal article  |  2018  |  Familial Cancer

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The Colon Cancer Family Registry Cohort

Mark A Jenkins, Aung K Win, Noralane M Lindor

Book Chapter  |  2018

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Enrichment of colorectal cancer associations in functional regions: Insight for using epigenomics data in the analysis of whole genome sequence-imputed GWAS data

Stephanie A Bien, Paul L Auer, Tabitha A Harrison, Conghui Qu, Charles M Connolly, Peyton G Greenside, Sai Chen, Sonja I Berndt, Stephane Bezieau, Hyun M Kang, Jeroen Huyghe, Hermann Brenner, Graham Casey, Andrew T Chan, John L Hopper, Barbara L Banbury, Jenny Chang-Claude, Stephen J Chanock, Robert W Haile, Michael Hoffmeister, et al.

Journal article  |  2017  |  PLOS ONE

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Inherited variation in circadian rhythm genes and risks of prostate cancer and three other cancer sites in combined cancer consortia

Fangyi Gu, Han Zhang, Paula L Hyland, Sonja Berndt, Susan M Gapstur, William Wheeler, Christopher I Amos, Stephane Bezieau, Heike Bickeboller, Hermann Brenner, Paul Brennan, Jenny Chang-Claude, David V Conti, Jennifer Anne Doherty, Stephen B Gruber, Tabitha A Harrison, Richard B Hayes, Michael Hoffmeister, Richard S Houlston, Rayjean J Hung, et al.

Journal article  |  2017  |  International Journal of Cancer

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Colorectal cancer incidence in path_MLH1 carriers subjected to different follow-up protocols: a Prospective Lynch Syndrome Database report

Toni Seppala, Kirsi Pylvanainen, Dafydd Gareth Evans, Heikki Jarvinen, Laura Renkonen-Sinisalo, Inge Bernstein, Elke Holinski-Feder, Paola Sala, Annika Lindblom, Finlay Macrae, Ignacio Blanco, Rolf Sijmons, Jacqueline Jeffries, Hans Vasen, John Burn, Sigve Nakken, Eivind Hovig, Einar Andreas Rodland, Kukatharmini Tharmaratnam, Wouter H de Vos tot Nederveen Cappel, et al.

Journal article  |  2017  |  Hereditary Cancer in Clinical Practice

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Pro-inflammatory fatty acid profile and colorectal cancer risk: A Mendelian randomisation analysis

Sebastian May-Wilson, Amit Sud, Philip J Law, Kimmo Palin, Sari Tuupanen, Alexandra Gylfe, Ulrika A Hanninen, Tatiana Cajuso, Tomas Tanskanen, Johanna Kondelin, Eevi Kaasinen, Antti-Pekka Sarin, Johan G Eriksson, Harri Rissanen, Paul Knekt, Eero Pukkala, Pekka Jousilahti, Veikko Salomaa, Samuli Ripatti, Aarno Palotie, et al.

Journal article  |  2017  |  European Journal of Cancer

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Incidence of and survival after subsequent cancers in carriers of pathogenic MMR variants with previous cancer: a report from the prospective Lynch syndrome database

Pal Moller, Toni Seppala, Inge Bernstein, Elke Holinski-Feder, Paola Sala, D Gareth Evans, Annika Lindblom, Finlay Macrae, Ignacio Blanco, Rolf Sijmons, Jacqueline Jeffries, Hans Vasen, John Burn, Sigve Nakken, Eivind Hovig, Einar Andreas Rodland, Kukatharmini Tharmaratnam, Wouter H de Vos Tot Nederveen Cappel, James Hill, Juul Wijnen, et al.

Journal article  |  2017  |  Gut

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Choosing not to undergo predictive genetic testing for hereditary colorectal cancer syndromes: expanding our understanding of decliners and declining

Louise A Keogh, Heather Niven, Alison Rutstein, Louisa Flander, Clara Gaff, Mark Jenkins

Journal article  |  2017  |  Journal of Behavioral Medicine

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Mendelian randomisation implicates hyperlipidaemia as a risk factor for colorectal cancer

Henry Rodriguez-Broadbent, Philip J Law, Amit Sud, Kimmo Palin, Sari Tuupanen, Alexandra Gylfe, Ulrika A Hanninen, Tatiana Cajuso, Tomas Tanskanen, Johanna Kondelin, Eevi Kaasinen, Antti-Pekka Sarin, Samuli Ripatti, Johan G Eriksson, Harri Rissanen, Paul Knekt, Eero Pukkala, Pekka Jousilahti, Veikko Salomaa, Aarno Palotie, et al.

Journal article  |  2017  |  International Journal of Cancer

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Lack of evidence for germline RNF43 mutations in patients with serrated polyposis syndrome from a large multinational study

Daniel D Buchanan, Mark Clendenning, Li Zhuoer, Jenna R Stewart, Sharelle Joseland, Sonja Woodall, Julie Arnold, Kara Semotiuk, Melyssa Aronson, Spring Holter, Steven Gallinger, Mark A Jenkins, Kevin Sweet, Finlay A Macrae, Ingrid M Winship, Susan Parry, Christophe Rosty

Journal article  |  2017  |  Gut

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Comparison of the efficiency of colorectal cancer screening programs based on age and genetic risk for reduction of colorectal cancer mortality

Oliver Stanesby, Mark Jenkins

Journal article  |  2017  |  European Journal of Human Genetics

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Development of a comprehensive colorectal cancer risk prediction tool (CRiPT) incorporating known and unknown major genes and polygenes

Aung Ko Win, Mark A Jenkins, James G Dowty, Antonis C Antoniou, Andrew Lee, Yingye Zheng, Noralane M Lindor, Polly A Newcomb, John L Hopper, Robert J MacInnis

Conference Proceedings  |  2017  |  Improving Cancer Risk Prediction for Prevention and Early Detection

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Mammographic density defined by higher than conventional brightness thresholds better predicts breast cancer risk

Tuong L Nguyen, Ye K Aung, Christopher F Evans, Gillian S Dite, Jennifer Stone, Robert J MacInnis, James G Dowty, Adrian Bickerstaffe, Kelly Aujard, Johanna M Rommens, Yun-Mi Song, Joohon Sung, Mark A Jenkins, Melissa C Southey, Graham G Giles, Carmel Apicella, John L Hopper

Journal article  |  2017  |  International Journal of Epidemiology

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Cohort Profile: The Tasmanian Longitudinal Health STUDY (TAHS)

Melanie C Matheson, Michael J Abramson, Katrina Allen, Geza Benke, John A Burgess, James G Dowty, Bircan Erbas, Iain H Feather, Peter A Frith, Graham G Giles, Lyle C Gurrin, Garun S Hamilton, John L Hopper, Alan L James, Mark A Jenkins, David P Johns, Caroline J Lodge, Adrian J Lowe, James Markos, Stephen C Morrison, et al.

Journal article  |  2017  |  International Journal of Epidemiology

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Lifetime alcohol intake is associated with an increased risk of KRAS plus and BRAF-/KRAS- but not BRAF plus colorectal cancer

Harindra Jayasekara, Robert J MacInnis, Elizabeth J Williamson, Allison M Hodge, Mark Clendenning, Christophe Rosty, Rhiannon Walters, Robin Room, Melissa C Southey, Mark A Jenkins, Roger L Milne, John L Hopper, Graham G Giles, Daniel D Buchanan, Dallas R English

Journal article  |  2017  |  International Journal of Cancer

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Testing for Gene-Environment Interactions Using a Prospective Family Cohort Design: Body Mass Index in Early and Later Adulthood and Risk of Breast Cancer

Gillian S Dite, Robert J MacInnis, Adrian Bickerstaffe, James G Dowty, Roger L Milne, Antonis C Antoniou, Prue Weideman, Carmel Apicella, Graham G Giles, Melissa C Southey, Mark A Jenkins, Kelly-Anne Phillips, Aung Ko Win, Mary Beth Terry, John L Hopper

Journal article  |  2017  |  American Journal of Epidemiology

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Germline miRNA DNA Variants and the Risk of Colorectal Cancer by Subtype

Noralane M Lindor, Melissa C Larson, Melissa S DeRycke, Shannon K McDonnell, Saurabh Baheti, Zachary C Fogarty, Aung Ko Win, John D Potter, Daniel D Buchanan, Mark Clendenning, Polly A Newcomb, Graham Casey, Steven Gallinger, Loic Le Marchand, John L Hopper, Mark A Jenkins, Ellen L Goode, Stephen N Thibodeau

Journal article  |  2017  |  Genes, Chromosomes and Cancer

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Prevalence and Penetrance of Major Genes and Polygenes for Colorectal Cancer

Aung Ko Win, Mark A Jenkins, James G Dowty, Antonis C Antoniou, Andrew Lee, Graham G Giles, Daniel D Buchanan, Mark Clendenning, Christophe Rosty, Dennis J Ahnen, Stephen N Thibodeau, Graham Casey, Steven Gallinger, Loic Le Marchand, Robert W Haile, John D Potter, Yingye Zheng, Noralane M Lindor, Polly A Newcomb, John L Hopper, et al.

Journal article  |  2017  |  Cancer Epidemiology Biomarkers and Prevention

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Modeling of Successive Cancer Risks in Lynch Syndrome Families in the Presence of Competing Risks Using Copulas

Yun-Hee Choi, Laurent Briollais, Aung K Win, John Hopper, Dan Buchanan, Mark Jenkins, Lajmi Lakhal-Chaieb

Journal article  |  2017  |  Biometrics

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Alcohol Consumption and the Risk of Colorectal Cancer for Mismatch Repair Gene Mutation Carriers

S Ghazaleh Dashti, Daniel D Buchanan, Harindra Jayasekara, Driss Ait Ouakrim, Mark Clendenning, Christophe Rosty, Ingrid M Winship, Finlay A Macrae, Graham G Giles, Susan Parry, Graham Casey, Robert W Haile, Steven Gallinger, Loic Le Marchand, Stephen N Thibodeau, Noralane M Lindor, Polly A Newcomb, John D Potter, John A Baron, John L Hopper, et al.

Journal article  |  2017  |  Cancer Epidemiology Biomarkers and Prevention

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Integrating personalised genomics into risk stratification models of population screening for colorectal cancer

Dayna Cenin, Peter O'Leary, Iris Lansdorp-Vogelaar, David Preen, Mark Jenkins, Eric Moses

Journal article  |  2017  |  Australian and New Zealand Journal of Public Health

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Tumor testing to identify lynch syndrome in two Australian colorectal cancer cohorts

Daniel D Buchanan, Mark Clendenning, Christophe Rosty, Stine V Eriksen, Michael D Walsh, Rhiannon J Walters, Stephen N Thibodeau, Jenna Stewart, Susan Preston, Aung Ko Win, Louisa Flander, Driss Ait Ouakrim, Finlay A Macrae, Alex Boussioutas, Ingrid M Winship, Graham G Giles, John L Hopper, Melissa C Southey, Dallas English, Mark A Jenkins

Journal article  |  2017  |  Journal of Gastroenterology and Hepatology

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Risk factors for metachronous colorectal cancer or polyp: A systematic review and meta-analysis

Harindra Jayasekara, Jeanette C Reece, Daniel D Buchanan, Dennis J Ahnen, Susan Parry, Mark A Jenkins, Aung Ko Win

Journal article  |  2017  |  JOURNAL OF GASTROENTEROLOGY AND HEPATOLOGY

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The CRISP colorectal cancer risk prediction tool: an exploratory study using simulated consultations in Australian primary care

Jennifer G Walker, Adrian Bickerstaffe, Nadira Hewabandu, Sanjay Maddumarachchi, James G Dowty Crecrc, Mark Jenkins, Marie Pirotta, Fiona M Walter, Jon D Emery

Journal article  |  2017  |  BMC Medical Informatics and Decision Making

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How does genetic risk information for Lynch syndrome translate to risk management behaviours?

Emma Steel, Andrew Robbins, Mark Jenkins, Louisa Flander, Clara Gaff, Louise Keogh

Journal article  |  2017  |  Hereditary Cancer in Clinical Practice

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Primary prevention

F Macrae, T Lockett, J Clarke, J Emery, M Jenkins, J McNeil, A Spigelman, A Win, R Woods, G Young, N Pachter, J Zalcbeg, undefined Cancer Council Australia Colorectal Cancer Guidelines Working Party

Book Chapter  |  2017

Colorectal cancer is the second most common non-skin cancer occurring in men and women in Australia, and the second most common ca..

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SNP rs16906252C > T Is an Expression and Methylation Quantitative Trait Locus Associated with an Increased Risk of Developing MGMT-Methylated Colorectal Cancer

Joice Kuroiwa-Trzmielina, Fan Wang, Robert W Rapkins, Robyn L Ward, Daniel D Buchanan, Aung Ko Win, Mark Clendenning, Christophe Rosty, Melissa C Southey, Ingrid M Winship, John L Hopper, Mark A Jenkins, Jake Olivier, Nicholas J Hawkins, Megan P Hitchins

Journal article  |  2016  |  Clinical Cancer Research

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Risk of extracolonic cancers for people with biallelic and monoallelic mutations in MUTYH

Aung Ko Win, Jeanette C Reece, James G Dowty, Daniel D Buchanan, Mark Clendenning, Christophe Rosty, Melissa C Southey, Joanne P Young, Sean P Cleary, Hyeja Kim, Michelle Cotterchio, Finlay A Macrae, Katherine M Tucker, John A Baron, Terrilea Burnett, Loic Le Marchand, Graham Casey, Robert W Haile, Polly A Newcomb, Stephen N Thibodeau, et al.

Journal article  |  2016  |  INTERNATIONAL JOURNAL OF CANCER

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Genome-Wide Interaction Analyses between Genetic Variants and Alcohol Consumption and Smoking for Risk of Colorectal Cancer

Jian Gong, Carolyn M Hutter, Polly A Newcomb, Cornelia M Ulrich, Stephanie A Bien, Peter T Campbell, John A Baron, Sonja I Berndt, Stephane Bezieau, Hermann Brenner, Graham Casey, Andrew T Chan, Jenny Chang-Claude, Mengmeng Du, David Duggan, Jane C Figueiredo, Steven Gallinger, Edward L Giovannucci, Robert W Haile, Tabitha A Harrison, et al.

Journal article  |  2016  |  PLOS Genetics

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Colorectal cancer screening is cost-effective in the elderly who have had less intense prior screening, high baseline risk of colorectal cancer and less comorbidities.

Mark Jenkins

Journal article  |  2016  |  Evidence Based Medicine

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Common variants in the obesity-associated genes FTO and MC4R are not associated with risk of colorectal cancer

Baiyu Yang, Aaron P Thrift, Jane C Figueiredo, Mark A Jenkins, Fredrick R Schumacher, David V Conti, Yi Lin, Aung Ko Win, Paul J Limburg, Sonja I Berndt, Hermann Brenner, Andrew T Chan, Jenny Chang-Claude, Michael Hoffmeister, Thomas J Hudson, Loic Le Marchand, Polly A Newcomb, Martha L Slattery, Emily White, Ulrike Peters, et al.

Journal article  |  2016  |  Cancer Epidemiology

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Associations of 5HTTLPR polymorphism with major depressive disorder and alcohol dependence: A systematic review and meta-analysis

Khine Zin Oo, Ye Kyaw Aung, Mark A Jenkins, Aung Ko Win

Journal article  |  2016  |  Australian & New Zealand Journal of Psychiatry

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Risk factors for metachronous colorectal cancer following a primary colorectal cancer: A prospective cohort study

Harindra Jayasekara, Jeanette C Reece, Daniel D Buchanan, Christophe Rosty, S Ghazaleh Dashti, Driss Ait Ouakrim, Ingrid M Winship, Finlay A Macrae, Alex Boussioutas, Graham G Giles, Dennis J Ahnen, Jan Lowery, Graham Casey, Robert W Haile, Steven Gallinger, Loic Le Marchand, Polly A Newcomb, Noralane M Lindor, John L Hopper, Susan Parry, et al.

Journal article  |  2016  |  INTERNATIONAL JOURNAL OF CANCER

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Cross-Cancer Genome-Wide Analysis of Lung, Ovary, Breast, Prostate, and Colorectal Cancer Reveals Novel Pleiotropic Associations

Gordon Fehringer, Peter Kraft, Paul D Pharoah, Rosalind A Eeles, Nilanjan Chatterjee, Fredrick R Schumacher, Joellen M Schildkraut, Sara Lindstrom, Paul Brennan, Heike Bickeboller, Richard S Houlston, Maria Teresa Landi, Neil Caporaso, Angela Risch, Ali Amin Al Olama, Sonja I Berndt, Edward L Giovannucci, Henrik Gronberg, Zsofia Kote-Jarai, Jing Ma, et al.

Journal article  |  2016  |  Cancer Research

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Association between Adult Height and Risk of Colorectal, Lung, and Prostate Cancer: Results from Meta-analyses of Prospective Studies and Mendelian Randomization Analyses

Nikhil K Khankari, Xiao-Ou Shu, Wanqing Wen, Peter Kraft, Sara Lindstrom, Ulrike Peters, Joellen Schildkraut, Fredrick Schumacher, Paolo Bofetta, Angela Risch, Heike Bickeboeller, Christopher I Amos, Douglas Easton, Rosalind A Eeles, Stephen B Gruber, Christopher A Haiman, David J Hunter, Stephen J Chanock, Brandon L Pierce, Wei Zheng

Journal article  |  2016  |  PLOS Medicine

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Development and External Validation of a Melanoma Risk Prediction Model Based on Self-assessed Risk Factors

Kylie Vuong, Bruce K Armstrong, Elisabete Weiderpass, Eiliv Lund, Hans-Olov Adami, Marit B Veierod, Jennifer H Barrett, John R Davies, D Timothy Bishop, David C Whiteman, Catherine M Olsen, John L Hopper, Graham J Mann, Anne E Cust, Kevin McGeechan

Journal article  |  2016  |  JAMA Dermatology

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Genetically Predicted Body Mass Index and Breast Cancer Risk: Mendelian Randomization Analyses of Data from 145,000 Women of European Descent

Yan Guo, Shaneda Warren Andersen, Xiao-Ou Shu, Kyriaki Michailidou, Manjeet K Bolla, Qin Wang, Montserrat Garcia-Closas, Roger L Milne, Marjanka K Schmidt, Jenny Chang-Claude, Allison Dunning, Stig E Bojesen, Habibul Ahsan, Kristiina Aittomaki, Irene L Andrulis, Hoda Anton-Culver, Volker Arndt, Matthias W Beckmann, Alicia Beeghly-Fadiel, Javier Benitez, et al.

Journal article  |  2016  |  PLOS Medicine

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Cholecystectomy and the risk of colorectal cancer by tumor mismatch repair deficiency status

Jie Shang, Jeanette C Reece, Daniel D Buchanan, Graham G Giles, Jane C Figueiredo, Graham Casey, Steven Gallinger, Stephen N Thibodeau, Noralane M Lindor, Polly A Newcomb, John D Potter, John A Baron, John L Hopper, Mark A Jenkins, Aung Ko Win

Journal article  |  2016  |  International Journal of Colorectal Disease

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Mendelian randomisation analysis strongly implicates adiposity with risk of developing colorectal cancer

David Jarvis, Jonathan S Mitchell, Philip J Law, Kimmo Palin, Sari Tuupanen, Alexandra Gylfe, Ulrika A Hanninen, Tatiana Cajuso, Tomas Tanskanen, Johanna Kondelin, Eevi Kaasinen, Antti-Pekka Sarin, Jaakko Kaprio, Johan G Eriksson, Harri Rissanen, Paul Knekt, Eero Pukkala, Pekka Jousilahti, Veikko Salomaa, Samuli Ripatti, et al.

Journal article  |  2016  |  British Journal of Cancer

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Fine-Mapping of Common Genetic Variants Associated with Colorectal Tumor Risk Identified Potential Functional Variants

Mengmeng Du, Shuo Jiao, Stephanie A Bien, Manish Gala, Goncalo Abecasis, Stephane Bezieau, Hermann Brenner, Katja Butterbach, Bette J Caan, Christopher S Carlson, Graham Casey, Jenny Chang-Claude, David V Conti, Keith R Curtis, David Duggan, Steven Gallinger, Robert W Haile, Tabitha A Harrison, Richard B Hayes, Michael Hoffmeister, et al.

Journal article  |  2016  |  PLOS ONE

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Variation at 2q35 (PNKD and TMBIM1) influences colorectal cancer risk and identifies a pleiotropic effect with inflammatory bowel disease

Giulia Orlando, Philip J Law, Kimmo Palin, Sari Tuupanen, Alexandra Gylfe, Ulrika A Hanninen, Tatiana Cajuso, Tomas Tanskanen, Johanna Kondelin, Eevi Kaasinen, Antti-Pekka Sarin, Jaakko Kaprio, Johan G Eriksson, Harri Rissanen, Paul Knekt, Eero Pukkala, Pekka Jousilahti, Veikko Salomaa, Samuli Ripatti, Aarno Palotie, et al.

Journal article  |  2016  |  Human Molecular Genetics

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Multivitamin, calcium and folic acid supplements and the risk of colorectal cancer in Lynch syndrome

Rowena Chau, Seyedeh Ghazaleh Dashti, Driss Ait Ouakrim, Daniel D Buchanan, Mark Clendenning, Christophe Rosty, Ingrid M Winship, Joanne P Young, Graham G Giles, Finlay A Macrae, Alex Boussioutas, Susan Parry, Jane C Figueiredo, A Joan Levine, Dennis J Ahnen, Graham Casey, Robert W Haile, Steven Gallinger, Loic Le Marchand, Stephen N Thibodeau, et al.

Journal article  |  2016  |  International Journal of Epidemiology

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Identification of Susceptibility Loci and Genes for Colorectal Cancer Risk

Chenjie Zeng, Koichi Matsuda, Wei-Hua Jia, Jiang Chang, Sun-Seog Kweon, Yong-Bing Xiang, Aesun Shin, Sun Ha Jee, Dong-Hyun Kim, Ben Zhang, Qiuyin Cai, Xingyi Guo, Jirong Long, Nan Wang, Regina Courtney, Zhi-Zhong Pan, Chen Wu, Atsushi Takahashi, Min-Ho Shin, Keitaro Matsuo, et al.

Journal article  |  2016  |  Gastroenterology

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Determining the familial risk distribution of colorectal cancer: a data mining approach

Rowena Chau, Mark A Jenkins, Daniel D Buchanan, Driss Ait Ouakrim, Graham G Giles, Graham Casey, Steven Gallinger, Robert W Haile, Loic Le Marchand, Polly A Newcomb, Noralane M Lindor, John L Hopper, Aung Ko Win

Journal article  |  2016  |  Familial Cancer

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GWASeq: targeted re-sequencing follow up to GWAS

Matthew P Salomon, Wai Lok Sibon Li, Christopher K Edlund, John Morrison, Barbara K Fortini, Aung Ko Win, David V Conti, Duncan C Thomas, David Duggan, Daniel D Buchanan, Mark A Jenkins, John L Hopper, Steven Gallinger, Loic Le Marchand, Polly A Newcomb, Graham Casey, Paul Marjoram

Journal article  |  2016  |  BMC Genomics

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Comparison of Prediction Models for Lynch Syndrome Among Individuals With Colorectal Cancer

Fay Kastrinos, Rohit P Ojha, Celine Leenen, Carmelita Alvero, Rowena C Mercado, Judith Balmana, Irene Valenzuela, Francesc Balaguer, Roger Green, Noralane M Lindor, Stephen N Thibodeau, Polly Newcomb, Aung Ko Win, Mark Jenkins, Daniel D Buchanan, Lucio Bertario, Paola Sala, Heather Hampel, Sapna Syngal, Ewout W Steyerberg

Journal article  |  2016  |  JNCI: Journal of the National Cancer Institute

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Childhood body mass index and adult mammographic density measures that predict breast cancer risk

John L Hopper, Tuong L Nguyen, Jennifer Stone, Kelly Aujard, Melanie C Matheson, Michael J Abramson, John A Burgess, E Haydn Walters, Gillian S Dite, Minh Bui, Christopher Evans, Enes Makalic, Daniel F Schmidt, Gail Ward, Mark A Jenkins, Graham G Giles, Shyamali C Dharmage, Carmel Apicella

Journal article  |  2016  |  Breast Cancer Research and Treatment

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Germline mutations in PMS2 and MLH1 in individuals with solitary loss of PMS2 expression in colorectal carcinomas from the Colon Cancer Family Registry Cohort

Christophe Rosty, Mark Clendenning, Michael D Walsh, Stine V Eriksen, Melissa C Southey, Ingrid M Winship, Finlay A Macrae, Alex Boussioutas, Nicola K Poplawski, Susan Parry, Julie Arnold, Joanne P Young, Graham Casey, Robert W Haile, Steven Gallinger, Loic Le Marchand, Polly A Newcomb, John D Potter, Melissa DeRycke, Noralane M Lindor, et al.

Journal article  |  2016  |  BMJ Open

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CYP24A1 variant modifies the association between use of oestrogen plus progestogen therapy and colorectal cancer risk

Xabier Garcia-Albeniz, Anja Rudolph, Carolyn Hutter, Emily White, Yi Lin, Stephanie A Rosse, Jane C Figueiredo, Tabitha A Harrison, Shuo Jiao, Hermann Brenner, Graham Casey, Thomas J Hudson, Mark Thornquist, Loic Le Marchand, John Potter, Martha L Slattery, Brent Zanke, John A Baron, Bette J Caan, Stephen J Chanock, et al.

Journal article  |  2016  |  British Journal of Cancer

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Quantifying the utility of single nucleotide polymorphisms to guide colorectal cancer screening

Mark A Jenkins, Enes Makalic, James G Dowty, Daniel F Schmidt, Gillian S Dite, Robert J MacInnis, Driss Ait Ouakrim, Mark Clendenning, Louisa B Flander, Oliver K Stanesby, John L Hopper, Aung K Win, Daniel D Buchanan

Journal article  |  2016  |  Future Oncology

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PMS2 monoallelic mutation carriers: the known unknown

McKinsey L Goodenberger, Brittany C Thomas, Douglas Riegert-Johnson, C Richard Boland, Sharon E Plon, Mark Clendenning, Aung Ko Win, Leigha Senter, Steven M Lipkin, Zsofia K Stadler, Finlay A Macrae, Henry T Lynch, Jeffrey N Weitzel, Albert de la Chapelle, Sapna Syngal, Patrick Lynch, Susan Parry, Mark A Jenkins, Steven Gallinger, Spring Holter, et al.

Journal article  |  2016  |  Genetics in Medicine

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Lynch syndrome and cervical cancer

Yoland C Antill, James G Dowty, Aung Ko Win, Tina Thompson, Michael D Walsh, Margaret C Cummings, Steven Gallinger, Noralane M Lindor, Loic Le Marchand, John L Hopper, Polly A Newcomb, Robert W Haile, James Church, Katherine M Tucker, Daniel D Buchanan, Joanne P Young, Ingrid M Winship, Mark A Jenkins

Journal article  |  2015  |  International Journal of Cancer

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Childhood cancers in families with and without Lynch syndrome

John A Heath, Jeanette C Reece, Daniel D Buchanan, Graham Casey, Carol A Durno, Steven Gallinger, Robert W Haile, Polly A Newcomb, John D Potter, Stephen N Thibodeau, Loic Le Marchand, Noralane M Lindor, John L Hopper, Mark A Jenkins, Aung Ko Win

Journal article  |  2015  |  Familial Cancer

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Risk of colorectal cancer for people with a mutation in both a MUTYH and a DNA mismatch repair gene

Aung Ko Win, Jeanette C Reece, Daniel D Buchanan, Mark Clendenning, Joanne P Young, Sean P Cleary, Hyeja Kim, Michelle Cotterchio, James G Dowty, Robert J MacInnis, Katherine M Tucker, Ingrid M Winship, Finlay A Macrae, Terrilea Burnett, Loic Le Marchand, Graham Casey, Robert W Haile, Polly A Newcomb, Stephen N Thibodeau, Noralane M Lindor, et al.

Journal article  |  2015  |  Familial Cancer

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Meta-analysis of genome-wide association studies identifies common susceptibility polymorphisms for colorectal and endometrial cancer near SH2B3 and TSHZ1

Timothy HT Cheng, Deborah Thompson, Jodie Painter, Tracy O'Mara, Maggie Gorman, Lynn Martin, Claire Palles, Angela Jones, Daniel D Buchanan, Aung Ko Win, John Hopper, Mark Jenkins, Noralane M Lindor, Polly A Newcomb, Steve Gallinger, David Conti, Fred Schumacher, Graham Casey, Graham G Giles, Paul Pharoah, et al.

Journal article  |  2015  |  Scientific Reports

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Mammographic density defined by higher than conventional brightness threshold better predicts breast cancer risk for full-field digital mammograms

Tuong Linh Nguyen, Ye Kyaw Aung, Christopher Francis Evans, Choi Yoon-Ho, Mark Anthony Jenkins, Joohon Sung, John Llewelyn Hopper, Yun-Mi Song

Journal article  |  2015  |  Breast Cancer Research

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Genetic variants within the hTERT gene and the risk of colorectal cancer in Lynch syndrome.

Aung Ko Win, Mark Clendenning, William Crawford, Christophe Rosty, Susan G Preston, Melissa C Southey, Susan Parry, Graham G Giles, Finlay A Macrae, Ingrid M Winship, John A Baron, John L Hopper, Mark A Jenkins, Daniel D Buchanan

Journal article  |  2015  |  Genes & Cancer

Lynch syndrome is an inherited cancer-predisposing disorder caused by germline mutations in the DNA mismatch repair (MMR) genes bu..

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A genome-wide association study for colorectal cancer identifies a risk locus in 14q23.1

Mathieu Lemire, Conghui Qu, Lenora WM Loo, Syed HE Zaidi, Hansong Wang, Sonja I Berndt, Stephane Bezieau, Hermann Brenner, Peter T Campbell, Andrew T Chan, Jenny Chang-Claude, Mengmeng Du, Christopher K Edlund, Steven Gallinger, Robert W Haile, Tabitha A Harrison, Michael Hoffmeister, John L Hopper, Lifang Hou, Li Hsu, et al.

Journal article  |  2015  |  Human Genetics

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Mutation Spectrum and Risk of Colorectal Cancer in African American Families with Lynch Syndrome

Rodrigo Santa Cruz Guindalini, Aung Ko Win, Cassandra Gulden, Noralane M Lindor, Polly A Newcomb, Robert W Haile, Victoria Raymond, Elena Stoffel, Michael Hall, Xavier Llor, Chinedu I Ukaegbu, Ilana Solomon, Jeffrey Weitzel, Matthew Kalady, Amie Blanco, Jonathan Terdiman, Gladis A Shuttlesworth, Patrick M Lynch, Heather Hampel, Henry T Lynch, et al.

Journal article  |  2015  |  Gastroenterology

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Trends in colorectal cancer mortality in Europe: retrospective analysis of the WHO mortality database

Driss Ait Ouakrim, Cecile Pizot, Magali Boniol, Matteo Malvezzi, Mathieu Boniol, Eva Negri, Maria Bota, Mark A Jenkins, Harry Bleiberg, Philippe Autier

Journal article  |  2015  |  BMJ

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Identification of a common variant with potential pleiotropic effect on risk of inflammatory bowel disease and colorectal cancer

Hamed Khalili, Jian Gong, Hermann Brenner, Thomas R Austin, Carolyn M Hutter, Yoshifumi Baba, John A Baron, Sonja I Berndt, Stephane Bezieau, Bette Caan, Peter T Campbell, Jenny Chang-Claude, Stephen J Chanock, Constance Chen, Li Hsu, Shuo Jiao, David V Conti, David Duggan, Charles S Fuchs, Manish Gala, et al.

Journal article  |  2015  |  Carcinogenesis

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Fertility after young-onset colorectal cancer: a study of subjects with Lynch syndrome

D Stupart, AK Win, IM Winship, M Jenkins

Journal article  |  2015  |  Colorectal Disease

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1054 Risk of extracolonic cancers for people with biallelic and monoallelic mutations in MUTYH

A Win, J Reece, J Dowty, D Buchanan, M Clendenning, J Young, S Cleary, M Cotterchio, F Macrae, J Baron, L Le Marchand, G Casey, R Haile, P Newcomb, S Thibodeau, J Hopper, S Gallinger, I Winship, N Lindor, M Jenkins

Conference Proceedings  |  2015  |  European Journal of Cancer

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Aspirin, Ibuprofen, and the Risk for Colorectal Cancer in Lynch Syndrome

Driss Ait Ouakrim, Seyedeh Ghazaleh Dashti, Rowena Chau, Daniel D Buchanan, Mark Clendenning, Christophe Rosty, Ingrid M Winship, Joanne P Young, Graham G Giles, Barbara Leggett, Finlay A Macrae, Dennis J Ahnen, Graham Casey, Steven Gallinger, Robert W Haile, Loic Le Marchand, Stephen N Thibodeau, Noralane M Lindor, Polly A Newcomb, John D Potter, et al.

Journal article  |  2015  |  Journal of the National Cancer Institute

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Association between Body Mass Index and Mortality for Colorectal Cancer Survivors: Overall and by Tumor Molecular Phenotype

Peter T Campbell, Christina C Newton, Polly A Newcomb, Amanda I Phipps, Dennis J Ahnen, John A Baron, Daniel D Buchanan, Graham Casey, Sean P Cleary, Michelle Cotterchio, Alton B Farris, Jane C Figueiredo, Steven Gallinger, Roger C Green, Robert W Haile, John L Hopper, Mark A Jenkins, Loic Le Marchand, Karen W Makar, John R McLaughlin, et al.

Journal article  |  2015  |  Cancer Epidemiology Biomarkers & Prevention

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Researchers Uncover Novel Spatially Defined Stem Cells

Tracy Hampton

Journal article  |  2015  |  JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION

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Female Hormonal Factors and the Risk of Endometrial Cancer in Lynch Syndrome

Seyedeh Ghazaleh Dashti, Rowena Chau, Driss Ait Ouakrim, Daniel D Buchanan, Mark Clendenning, Joanne P Young, Ingrid M Winship, Julie Arnold, Dennis J Ahnen, Robert W Haile, Graham Casey, Steven Gallinger, Stephen N Thibodeau, Noralane M Lindor, Loic Le Marchand, Polly A Newcomb, John D Potter, John A Baron, John L Hopper, Mark A Jenkins, et al.

Journal article  |  2015  |  JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION

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Genome-wide association study of colorectal cancer identifies six new susceptibility loci

Fredrick R Schumacher, Stephanie L Schmit, Shuo Jiao, Christopher K Edlund, Hansong Wang, Ben Zhang, Li Hsu, Shu-Chen Huang, Christopher P Fischer, John F Harju, Gregory E Idos, Flavio Lejbkowicz, Frank J Manion, Kevin McDonnell, Caroline E McNeil, Marilena Melas, Hedy S Rennert, Wei Shi, Duncan C Thomas, David J Van Den Berg, et al.

Journal article  |  2015  |  Nature Communications

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Prediagnostic Physical Activity and Colorectal Cancer Survival: Overall and Stratified by Tumor Characteristics

Sheetal Hardikar, Polly A Newcomb, Peter T Campbell, Aung Ko Win, Noralane M Lindor, Daniel D Buchanan, Karen W Makar, Mark A Jenkins, John D Potter, Amanda I Phipps

Journal article  |  2015  |  Cancer Epidemiology Biomarkers & Prevention

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Mendelian Randomization Study of Body Mass Index and Colorectal Cancer Risk

Aaron P Thrift, Jian Gong, Ulrike Peters, Jenny Chang-Claude, Anja Rudolph, Martha L Slattery, Andrew T Chan, Adame Locke, Bratati Kahali, Anne E Justice, Tune H Pers, Steven Gallinger, Richard B Hayes, John A Baron, Bette J Caan, Shuji Ogino, Sonja I Berndt, Stephen J Chanock, Graham Casey, Robert W Haile, et al.

Journal article  |  2015  |  Cancer Epidemiology Biomarkers & Prevention

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Consequences of germline variation disrupting the constitutional translational initiation codon start sites of MLH1 and BRCA2: Use of potential alternative start sites and implications for predicting variant pathogenicity

Michael T Parsons, Phillip J Whiley, Jonathan Beesley, Mark Drost, Niels de Wind, Bryony A Thompson, Louise Marquart, John L Hopper, Mark A Jenkins, Melissa A Brown, Kathy Tucker, Linda Warwick, Daniel D Buchanan, Amanda B Spurdle

Journal article  |  2015  |  Molecular Carcinogenesis

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A new GWAS and meta-analysis with 1000Genomes imputation identifies novel risk variants for colorectal cancer (vol 5, 10442, 2015)

Nada A Al-Tassan, Nicola Whiffin, Fay J Hosking, Claire Palles, Susan M Farrington, Sara E Dobbins, Rebecca Harris, Maggie Gorman, Albert Tenesa, Brian F Meyer, Salma M Wakil, Ben Kinnersley, Harry Campbell, Lynn Martin, Christopher G Smith, Shelley Idziaszczyk, Ella Barclay, Timothy S Maughan, Richard Kaplan, Rachel Kerr, et al.

Journal article  |  2015  |  Scientific Reports

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A new GWAS and meta-analysis with 1000Genomes imputation identifies novel risk variants for colorectal cancer

Nada A Al-Tassan, Nicola Whiffin, Fay J Hosking, Claire Palles, Susan M Farrington, Sara E Dobbins, Rebecca Harris, Maggie Gorman, Albert Tenesa, Brian F Meyer, Salma M Wakil, Ben Kinnersley, Harry Campbell, Lynn Martin, Christopher G Smith, Shelley Idziaszczyk, Ella Barclay, Timothy S Maughan, Richard Kaplan, Rachel Kerr, et al.

Journal article  |  2015  |  Scientific Reports

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Inhibition of CD23-mediated IgE transcytosis suppresses the initiation and development of airway allergic inflammation

Senthilkumar Palaniyandi, Xiaoyang Liu, Sivakumar Periasamy, Aiying Ma, Jin Tang, Mark Jenkins, Wenbin Tuo, Wenxia Song, Achsah Keegan, Daniel Conrad, Xiaoping Zhu

Conference Proceedings  |  2015  |  Mucosal Immunology

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Germline TP53 Mutations in Patients With Early-Onset Colorectal Cancer in the Colon Cancer Family Registry

Matthew B Yurgelun, Serena Masciari, Victoria A Joshi, Rowena C Mercado, Noralane M Lindor, Steven Gallinger, John L Hopper, Mark A Jenkins, Daniel D Buchanan, Polly A Newcomb, John D Potter, Robert W Haile, Raju Kucherlapati, Sapna Syngal

Journal article  |  2015  |  JAMA Oncology

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Accuracy of Self-Reported Nevus and Pigmentation Phenotype Compared with Clinical Assessment in a Population-Based Study of Young Australian Adults

Anne E Cust, Kristen M Pickles, Chris Goumas, Thao Vu, Helen Schmid, Eduardo Nagore, John Kelly, Joanne F Aitken, Graham G Giles, John L Hopper, Mark A Jenkins, Graham J Mann

Journal article  |  2015  |  Cancer Epidemiology Biomarkers & Prevention

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Mendelian randomization study of height and risk of colorectal cancer

Aaron P Thrift, Jian Gong, Ulrike Peters, Jenny Chang-Claude, Anja Rudolph, Martha L Slattery, Andrew T Chan, Tonu Esko, Andrew R Wood, Jian Yang, Sailaja Vedantam, Stefan Gustafsson, Tune H Pers, John A Baron, Stephane Bezieau, Sebastien Kuery, Shuji Ogino, Sonja I Berndt, Graham Casey, Robert W Haile, et al.

Journal article  |  2015  |  International Journal of Epidemiology

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Association of Aspirin and NSAID Use With Risk of Colorectal Cancer According to Genetic Variants

Hongmei Nan, Carolyn M Hutter, Yi Lin, Eric J Jacobs, Cornelia M Ulrich, Emily White, John A Baron, Sonja I Berndt, Hermann Brenner, Katja Butterbach, Bette J Caan, Peter T Campbell, Christopher S Carlson, Graham Casey, Jenny Chang-Claude, Stephen J Chanock, Michelle Cotterchio, David Duggan, Jane C Figueiredo, Charles S Fuchs, et al.

Journal article  |  2015  |  JAMA

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Common colorectal cancer risk alleles contribute to the multiple colorectal adenoma phenotype, but do not influence colonic polyposis in FAP

Timothy HT Cheng, Maggie Gorman, Lynn Martin, Ella Barclay, Graham Casey, Brian Saunders, Huw Thomas, Sue Clark, Ian Tomlinson

Journal article  |  2015  |  European Journal of Human Genetics

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Short-Term Risk of Colorectal Cancer in Individuals With Lynch Syndrome: A Meta-Analysis

Mark A Jenkins, James G Dowty, Driss Ait Ouakrim, John D Mathews, John L Hopper, Youenn Drouet, Christine Lasset, Valerie Bonadona, Aung Ko Win

Journal article  |  2015  |  Journal of Clinical Oncology

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Role of tumour molecular and pathology features to estimate colorectal cancer risk for first-degree relatives

Aung Ko Win, Daniel D Buchanan, Christophe Rosty, Robert J MacInnis, James G Dowty, Gillian S Dite, Graham G Giles, Melissa C Southey, Joanne P Young, Mark Clendenning, Michael D Walsh, Rhiannon J Walters, Alex Boussioutas, Thomas C Smyrk, Stephen N Thibodeau, John A Baron, John D Potter, Polly A Newcomb, Loic Le Marchand, Robert W Haile, et al.

Journal article  |  2015  |  Gut

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Red Meat Intake, NAT2, and Risk of Colorectal Cancer: A Pooled Analysis of 11 Studies

Ashwin N Ananthakrishnan, Mengmeng Du, Sonja I Berndt, Hermann Brenner, Bette J Caan, Graham Casey, Jenny Chang-Claude, David Duggan, Charles S Fuchs, Steven Gallinger, Edward L Giovannucci, Tabitha A Harrison, Richard B Hayes, Michael Hoffmeister, John L Hopper, Lifang Hou, Li Hsu, Mark A Jenkins, Peter Kraft, Jing Ma, et al.

Journal article  |  2015  |  Cancer Epidemiology Biomarkers & Prevention

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High prevalence of mismatch repair deficiency in prostate cancers diagnosed in mismatch repair gene mutation carriers from the colon cancer family registry

Christophe Rosty, Michael D Walsh, Noralane M Lindor, Stephen N Thibodeau, Erin Mundt, Steven Gallinger, Melyssa Aronson, Aaron Pollett, John A Baron, Sally Pearson, Mark Clendenning, Rhiannon J Walters, Belinda N Nagler, William J Crawford, Joanne P Young, Ingrid Winship, Aung Ko Win, John L Hopper, Mark A Jenkins, Daniel D Buchanan

Journal article  |  2014  |  Familial Cancer

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No Evidence of Gene-Calcium Interactions from Genome-Wide Analysis of Colorectal Cancer Risk

Mengmeng Du, Xuehong Zhang, Michael Hoffmeister, Robert E Schoen, John A Baron, Sonja I Berndt, Hermann Brenner, Christopher S Carlson, Graham Casey, Andrew T Chan, Keith R Curtis, David Duggan, W James Gauderman, Edward L Giovannucci, Jian Gong, Tabitha A Harrison, Richard B Hayes, Brian E Henderson, John L Hopper, Li Hsu, et al.

Journal article  |  2014  |  Cancer Epidemiology Biomarkers & Prevention

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Prevalence and predictors of germline CDKN2A mutations for melanoma cases from Australia, Spain and the United Kingdom

Mark Harland, Anne E Cust, Celia Badenas, Yu-Mei Chang, Elizabeth A Holland, Paula Aguilera, Joanne F Aitken, Bruce K Armstrong, Jennifer H Barrett, Cristina Carrera, May Chan, Joanne Gascoyne, Graham G Giles, Chantelle Agha-Hamilton, John L Hopper, Mark A Jenkins, Peter A Kanetsky, Richard F Kefford, Isabel Kolm, Johanna Lowery, et al.

Journal article  |  2014  |  Hereditary Cancer in Clinical Practice

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A novel colorectal cancer risk locus at 4q32.2 identified from an international genome-wide association study

Stephanie L Schmit, Fredrick R Schumacher, Christopher K Edlund, David V Conti, Leon Raskin, Flavio Lejbkowicz, Mila Pinchev, Hedy S Rennert, Mark A Jenkins, John L Hopper, Daniel D Buchanan, Noralane M Lindor, Loic Le Marchand, Steven Gallinger, Robert W Haile, Polly A Newcomb, Shu-Chen Huang, Gad Rennert, Graham Casey, Stephen B Gruber

Journal article  |  2014  |  Carcinogenesis

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Should the grading of colorectal adenocarcinoma include microsatellite instability status?

Christophe Rosty, Elizabeth J Williamson, Mark Clendenning, Rhiannon J Walters, Aung K Win, Mark A Jenkins, John L Hopper, Ingrid M Winship, Melissa C Southey, Graham G Giles, Dallas R English, Daniel D Buchanan

Journal article  |  2014  |  Human Pathology

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Identification of a melanoma susceptibility locus and somatic mutation in TET2

Fengju Song, Christopher I Amos, Jeffrey E Lee, Christine G Lian, Shenying Fang, Hongliang Liu, Stuart MacGregor, Mark M Iles, Matthew H Law, Neal I Lindeman, Grant W Montgomery, David L Duffy, Anne E Cust, Mark A Jenkins, David C Whiteman, Richard F Kefford, Graham G Giles, Bruce K Armstrong, Joanne F Aitken, John L Hopper, et al.

Journal article  |  2014  |  Carcinogenesis

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Gene-Environment Interaction Involving Recently Identified Colorectal Cancer Susceptibility Loci

Elizabeth D Kantor, Carolyn M Hutter, Jessica Minnier, Sonja I Berndt, Hermann Brenner, Bette J Caan, Peter T Campbell, Christopher S Carlson, Graham Casey, Andrew T Chan, Jenny Chang-Claude, Stephen J Chanock, Michelle Cotterchio, Mengmeng Du, David Duggan, Charles S Fuchs, Edward L Giovannucci, Jian Gong, Tabitha A Harrison, Richard B Hayes, et al.

Journal article  |  2014  |  Cancer Epidemiology Biomarkers & Prevention

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Identification of susceptibility loci for colorectal cancer in a genome-wide meta-analysis

Nicola Whiffin, Fay J Hosking, Susan M Farrington, Claire Palles, Sara E Dobbins, Lina Zgaga, Amy Lloyd, Ben Kinnersley, Maggie Gorman, Albert Tenesa, Peter Broderick, Yufei Wang, Ella Barclay, Caroline Hayward, Lynn Martin, Daniel D Buchanan, Aung Ko Win, John Hopper, Mark Jenkins, Noralane M Lindor, et al.

Journal article  |  2014  |  Human Molecular Genetics

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Fertility and apparent genetic anticipation in Lynch syndrome

Douglas Stupart, Aung Ko Win, Mark Jenkins, Ingrid M Winship, Paul Goldberg, Rajkumar Ramesar

Journal article  |  2014  |  Familial Cancer

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Trans-ethnic genome-wide association study of colorectal cancer identifies a new susceptibility locus in VTI1A

Hansong Wang, Terrilea Burnett, Suminori Kono, Christopher A Haiman, Motoki Iwasaki, Lynne R Wilkens, Lenora WM Loo, David Van den Berg, Laurence N Kolonel, Brian E Henderson, Temitope O Keku, Robert S Sandler, Lisa B Signorello, William J Blot, Polly A Newcomb, Mala Pande, Christopher I Amos, Dee W West, Stephane Bezieau, Sonja I Berndt, et al.

Journal article  |  2014  |  Nature Communications

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Re: Microsatellite Instability and BRAF Mutation Testing in Colorectal Cancer Prognostication

Christophe Rosty, Elizabeth J Wiliamson, Mark Clendening, Rhianon J Walters, Michael D Walsh, Aung K Win, Mark A Jenkins, John L Hoper, Ingrid Winship, Melisa C Southey, Graham G Giles, Dalas R English, Daniel D Buchanan

Journal article  |  2014  |  JNCI Journal of the National Cancer Institute

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Family History of Colorectal Cancer Is Not Associated with Colorectal Cancer Survival Regardless of Microsatellite Instability Status

Amanda I Phipps, Dennis J Ahnen, Peter T Campbell, Aung Ko Win, Mark A Jenkins, Noralane M Lindor, Robert Gryfe, John D Potter, Polly A Newcomb

Journal article  |  2014  |  Cancer Epidemiology, Biomarkers & Prevention

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Characterisation of Familial Colorectal Cancer Type X, Lynch syndrome, and non-familial colorectal cancer

S Shiovitz, WK Copeland, MN Passarelli, AN Burnett-Hartman, WM Grady, JD Potter, S Gallinger, DD Buchanan, C Rosty, AK Win, M Jenkins, SN Thibodeau, R Haile, JA Baron, LL Marchand, PA Newcomb, NM Lindor

Journal article  |  2014  |  British Journal of Cancer

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Genetic Variation in UGT Genes Modify the Associations of NSAIDs with Risk of Colorectal Cancer: Colon Cancer Family Registry

Dominique Scherer, Lisel M Koepl, Elizabeth M Poole, Yesilda Balavarca, Liren Xiao, John A Baron, Li Hsu, Anna E Coghill, Peter T Campbell, Sarah E Kleinstein, Jane C Figueiredo, Johanna W Lampe, Katharina Buck, John D Potter, Richard J Kulmacz, Mark A Jenkins, John L Hopper, Aung K Win, Polly A Newcomb, Cornelia M Ulrich, et al.

Journal article  |  2014  |  Genes, Chromosomes & Cancer

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Occupational sun exposure and risk of melanoma according to anatomical site

Kylie Vuong, Kevin McGeechan, Bruce K Armstrong, Anne E Cust

Journal article  |  2014  |  International Journal of Cancer

Although sunburn and intermittent sun exposures are associated with increased melanoma risk, most studies have found null or inver..

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Does risk of endometrial cancer for women without a germline mutation in a DNA mismatch repair gene depend on family history of endometrial cancer or colorectal cancer?

Rajani Bharati, Mark A Jenkins, Noralane M Lindor, Loic Le Marchand, Steven Gallinger, Robert W Haile, Polly A Newcomb, John L Hopper, Aung Ko Win

Journal article  |  2014  |  Gynecologic Oncology

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Pleiotropic effects of genetic risk variants for other cancers on colorectal cancer risk: PAGE, GECCO and CCFR consortia

Iona Cheng, Jonathan M Kocarnik, Logan Dumitrescu, Noralane M Lindor, Jenny Chang-Claude, Christy L Avery, Christian P Caberto, Shelly-Ann Love, Martha L Slattery, Andrew T Chan, John A Baron, Lucia A Hindorff, Sungshim Lani Park, Fredrick R Schumacher, Michael Hoffmeister, Peter Kraft, Anne M Butler, David J Duggan, Lifang Hou, Chris S Carlson, et al.

Journal article  |  2014  |  Gut

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Risk of Colorectal Cancer for Carriers of Mutations in MUTYH, With and Without a Family History of Cancer

Aung Ko Win, James G Dowty, Sean P Cleary, Hyeja Kim, Daniel D Buchanan, Joanne P Young, Mark Clendenning, Christophe Rosty, Robert J MacInnis, Graham G Giles, Alex Boussioutas, Finlay A Macrae, Susan Parry, Jack Goldblatt, John A Baron, Terrilea Burnett, Loic Le Marchand, Polly A Newcomb, Robert W Haile, John L Hopper, et al.

Journal article  |  2014  |  Gastroenterology

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Cost-effectiveness of family history-based colorectal cancer screening in Australia

Driss A Ouakrim, Alex Boussioutas, Trevor Lockett, John L Hopper, Mark A Jenkins

Journal article  |  2014  |  BMC Cancer

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A Genome-wide Association Study of Early-Onset Breast Cancer Identifies PFKM as a Novel Breast Cancer Gene and Supports a Common Genetic Spectrum for Breast Cancer at Any Age

Habibul Ahsan, Jerry Halpern, Muhammad G Kibriya, Brandon L Pierce, Lin Tong, Eric Gamazon, Valerie McGuire, Anna Felberg, Jianxin Shi, Farzana Jasmine, Shantanu Roy, Rachelle Brutus, Maria Argos, Stephanie Melkonian, Jenny Chang-Claude, Irene Andrulis, John L Hopper, Esther M John, Kathi Malone, Giske Ursin, et al.

Journal article  |  2014  |  Cancer Epidemiology, Biomarkers & Prevention

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Genome-Wide Diet-Gene Interaction Analyses for Risk of Colorectal Cancer

Jane C Figueiredo, Li Hsu, Carolyn M Hutter, Yi Lin, Peter T Campbell, John A Baron, Sonja I Berndt, Shuo Jiao, Graham Casey, Barbara Fortini, Andrew T Chan, Michelle Cotterchio, Mathieu Lemire, Steven Gallinger, Tabitha A Harrison, Loic Le Marchand, Polly A Newcomb, Martha L Slattery, Bette J Caan, Christopher S Carlson, et al.

Journal article  |  2014  |  PLoS Genetics

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Risk of Prostate Cancer in Lynch Syndrome: A Systematic Review and Meta-analysis

Shae Ryan, Mark A Jenkins, Aung Ko Win

Journal article  |  2014  |  Cancer Epidemiology, Biomarkers & Prevention

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Contribution of MC1R Genotype and Novel Common Genomic Variants to Melanoma Risk Prediction

AE Cust, M Bui, C Goumas, MA Jenkins

Conference Proceedings  |  2014  |  Cancer Epidemiology Biomarkers & Prevention

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The Association of Telomere Length with Colorectal Cancer Differs by the Age of Cancer Onset

Lisa A Boardman, Kristin Litzelman, Songwon Seo, Ruth A Johnson, Russell J Vanderboom, Grace W Kimmel, Julie M Cunningham, Ronald E Gangnon, Corinne D Engelman, Douglas L Riegert-Johnson, John Potter, Robert Haile, Daniel Buchanan, Mark A Jenkins, David N Rider, Stephen N Thibodeau, Gloria M Petersen, Halcyon G Skinner

Journal article  |  2014  |  Clinical and Translational Gastroenterology

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Application of a 5-tiered scheme for standardized classification of 2,360 unique mismatch repair gene variants in the InSiGHT locus-specific database

Bryony A Thompson, Amanda B Spurdle, John-Paul Plazzer, Marc S Greenblatt, Kiwamu Akagi, Fahd Al-Mulla, Bharati Bapat, Inge Bernstein, Gabriel Capella, Johan T den Dunnen, Desiree du Sart, Aurelie Fabre, Michael P Farrell, Susan M Farrington, Ian M Frayling, Thierry Frebourg, David E Goldgar, Christopher D Heinen, Elke Holinski-Feder, Maija Kohonen-Corish, et al.

Journal article  |  2014  |  Nature Genetics

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Predictive Genetic Testing of a Bone Marrow Recipient-Ethical Issues Involving Unexpected Results, Gender Issues, Test Accuracy, and Implications for the Donor

A Sexton, L Rawlings, M Jenkins, I Winship

Journal article  |  2014  |  Journal of Genetic Counseling

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Perceived Versus Predicted Risks of Colorectal Cancer and Self-Reported Colonoscopies by Members of Mismatch Repair Gene Mutation-Carrying Families Who Have Declined Genetic Testing

Louisa Flander, Andrew Speirs-Bridge, Alison Rutstein, Heather Niven, Aung Ko Win, Driss Ait Ouakrim, John L Hopper, Finlay Macrae, Louise Keogh, Clara Gaff, Mark Jenkins

Journal article  |  2014  |  Journal of Genetic Counseling

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Risk profiling: Familial colorectal cancer

AK Win, DA Ouakrim, MA Jenkins

Journal article  |  2014  |  Cancer Forum

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Deciphering the genetic architecture of low-penetrance susceptibility to colorectal cancer

Nicola Whiffin, Sara E Dobbins, Fay J Hosking, Claire Palles, Albert Tenesa, Yufei Wang, Susan M Farrington, Angela M Jones, Peter Broderick, Harry Campbell, Polly A Newcomb, Graham Casey, David V Conti, Fred Schumacher, Steve Gallinger, Noralane M Lindor, John Hopper, Mark Jenkins, Malcolm G Dunlop, Ian P Tomlinson, et al.

Journal article  |  2013  |  Human Molecular Genetics

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Expression of MUC2, MUC5AC, MUC5B, and MUC6 mucins in colorectal cancers and their association with the CpG island methylator phenotype

Michael D Walsh, Mark Clendenning, Elizabeth Williamson, Sally-Ann Pearson, Rhiannon J Walters, Belinda Nagler, David Packenas, Aung K Win, John L Hopper, Mark A Jenkins, Andrew M Haydon, Christophe Rosty, Dallas R English, Graham G Giles, Michael A McGuckin, Joanne P Young, Daniel D Buchanan

Journal article  |  2013  |  Modern Pathology

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Criteria and prediction models for mismatch repair gene mutations: a review

Aung Ko Win, Robert J MacInnis, James G Dowty, Mark A Jenkins

Journal article  |  2013  |  Journal of Medical Genetics

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Re: Risks of Colorectal and Other Cancers After Endometrial Cancer for Women With Lynch Syndrome Response

Aung Ko Win, Mark A Jenkins

Journal article  |  2013  |  Journal of the National Cancer Institute

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Genetic Predictors of Circulating 25-Hydroxyvitamin D and Risk of Colorectal Cancer

Linda T Hiraki, Conghui Qu, Carolyn M Hutter, John A Baron, Sonja I Berndt, Stephane Bezieau, Hermann Brenner, Bette J Caan, Graham Casey, Jenny Chang-Claude, Stephen J Chanock, David V Conti, David Duggan, Charles S Fuchs, Steven Gallinger, Edward L Giovannucci, Tabitha A Harrison, Richard B Hayes, Aditi Hazra, Brian Henderson, et al.

Journal article  |  2013  |  Cancer Epidemiology, Biomarkers & Prevention

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Telomere Length Varies By DNA Extraction Method: Implications for Epidemiologic Research

Julie M Cunningham, Ruth A Johnson, Kristin Litzelman, Halcyon G Skinner, Songwon Seo, Corinne D Engelman, Russell J Vanderboom, Grace W Kimmel, Ronald E Gangnon, Douglas L Riegert-Johnson, John A Baron, John D Potter, Robert Haile, Daniel D Buchanan, Mark A Jenkins, David N Rider, Stephen N Thibodeau, Gloria M Petersen, Lisa A Boardman

Journal article  |  2013  |  Cancer Epidemiology, Biomarkers & Prevention

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A new regulatory variant in the interleukin-6 receptor gene associates with asthma risk

JA Revez, L Bain, B Chapman, JE Powell, R Jansen, DL Duffy, JY Tung, BW Penninx, PM Visscher, EJC De Geus, DI Boomsma, DA Hinds, NG Martin, GW Montgomery, MAR Ferreira

Journal article  |  2013  |  Genes & Immunity

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BRAFV600E Immunohistochemistry Facilitates Universal Screening of Colorectal Cancers for Lynch Syndrome

Christopher W Toon, Michael D Walsh, Angela Chou, David Capper, Adele Clarkson, Loretta Sioson, Stephen Clarke, Scott Mead, Rhiannon J Walters, Mark Clendenning, Christophe Rosty, Joanne P Young, Aung Ko Win, John L Hopper, Ashley Crook, Andreas von Deimling, Mark A Jenkins, Daniel D Buchanan, Anthony J Gill

Journal article  |  2013  |  American Journal of Surgical Pathology

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Is the reported modifying effect of 8q23.3 and 11q23.1 on colorectal cancer risk for MLH1 mutation carriers valid?

Aung Ko Win, Mark A Jenkins

Journal article  |  2013  |  International Journal of Cancer

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MC1R genotype as a predictor of early-onset melanoma, compared with self-reported and physician-measured traditional risk factors: an Australian case-control-family study

Anne E Cust, Chris Goumas, Kylie Vuong, John R Davies, Jennifer H Barrett, Elizabeth A Holland, Helen Schmid, Chantelle Agha-Hamilton, Bruce K Armstrong, Richard F Kefford, Joanne F Aitken, Graham G Giles, D Timothy Bishop, Julia A Newton-Bishop, John L Hopper, Graham J Mann, Mark A Jenkins

Journal article  |  2013  |  BMC Cancer

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Detection of large scale 3 ' deletions in the PMS2 gene amongst Colon-CFR participants: have we been missing anything?

Mark Clendenning, Michael D Walsh, Judith Balmana Gelpi, Stephen N Thibodeau, Noralane Lindor, John D Potter, Polly Newcomb, Loic LeMarchand, Robert Haile, Steve Gallinger, John L Hopper, Mark A Jenkins, Christophe Rosty, Joanne P Young, Daniel D Buchanan

Journal article  |  2013  |  Familial Cancer

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Trends in colorectal cancer mortality and screening activities in European countries

P Autier, D Ait Ouakrim, M Malvezzi, H Bleiberg, M Jenkins, M Boniol, E Negri

Conference Proceedings  |  2013  |  EUROPEAN JOURNAL OF CANCER

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Screening participation for people at increased risk of colorectal cancer due to family history: a systematic review and meta-analysis

Driss Ait Ouakrim, Trevor Lockett, Alex Boussioutas, John L Hopper, Mark A Jenkins

Journal article  |  2013  |  Familial Cancer

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Germline HOXB13 p.Gly84Glu mutation and risk of colorectal cancer

Mohammad R Akbari, Laura N Anderson, Daniel D Buchanan, Mark Clendenning, Mark A Jenkins, Aung Ko Win, John L Hopper, Graham G Giles, Robert Nam, Steven Narod, Steven Gallinger, Sean P Cleary

Journal article  |  2013  |  Cancer Epidemiology

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Colon and Rectal Cancer Survival by Tumor Location and Microsatellite Instability: The Colon Cancer Family Registry

Amanda I Phipps, Noralane M Lindor, Mark A Jenkins, John A Baron, Aung Ko Win, Steven Gallinger, Robert Gryfe, Polly A Newcomb

Journal article  |  2013  |  Diseases of the Colon and Rectum

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Lynch syndrome-associated breast cancers do not overexpress chromosome 11-encoded mucins

Michael D Walsh, Margaret C Cummings, Sally-Ann Pearson, Mark Clendenning, Rhiannon J Walters, Belinda Nagler, John L Hopper, Mark A Jenkins, Graeme K Suthers, Jack Goldblatt, Kathy Tucker, Michael R Gattas, Julie L Arnold, Susan Parry, Finlay A Macrae, Michael A McGuckin, Joanne P Young, Daniel D Buchanan

Journal article  |  2013  |  Modern Pathology

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Association between hypermethylation of DNA repetitive elements in white blood cell DNA and early-onset colorectal cancer

Rhiannon J Walters, Elizabeth J Williamson, Dallas R English, Joanne P Young, Christophe Rosty, Mark Clendenning, Michael D Walsh, Susan Parry, Dennis J Ahnen, John A Baron, Aung Ko Win, Graham G Giles, John L Hopper, Mark A Jenkins, Daniel D Buchanan

Journal article  |  2013  |  Epigenetics

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Identification of Novel Variants in Colorectal Cancer Families by High-Throughput Exome Sequencing

Melissa S DeRycke, Shanaka R Gunawardena, Sumit Middha, Yan W Asmann, Daniel J Schaid, Shannon K McDonnell, Shaun M Riska, Bruce W Eckloff, Julie M Cunningham, Brooke L Fridley, Daniel J Serie, William R Bamlet, Mine S Cicek, Mark A Jenkins, David J Duggan, Daniel Buchanan, Mark Clendenning, Robert W Haile, Michael O Woods, Steven N Gallinger, et al.

Journal article  |  2013  |  Cancer Epidemiology, Biomarkers & Prevention

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Germline Mutations in the Polyposis-Associated Genes BMPR1A, SMAD4, PTEN, MUTYH and GREM1 Are Not Common in Individuals with Serrated Polyposis Syndrome

Mark Clendenning, Joanne P Young, Michael D Walsh, Sonja Woodall, Julie Arnold, Mark Jenkins, Aung Ko Win, John L Hopper, Kevin Sweet, Steven Gallinger, Christophe Rosty, Susan Parry, Daniel D Buchanan

Journal article  |  2013  |  PLoS One

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PIK3CA Activating Mutation in Colorectal Carcinoma: Associations with Molecular Features and Survival

Christophe Rosty, Joanne P Young, Michael D Walsh, Mark Clendenning, Kristy Sanderson, Rhiannon J Walters, Susan Parry, Mark A Jenkins, Aung Ko Win, Melissa C Southey, John L Hopper, Graham G Giles, Elizabeth J Williamson, Dallas R English, Daniel D Buchanan

Journal article  |  2013  |  PLoS One

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Dilemma in Pulmonary Metastasectomy Video-Assisted Thoracoscopic Surgery or Thoracotomy? Response

Jens Eckardt, Peter Bjorn Licht

Journal article  |  2013  |  Chest

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Risk of Metachronous Colon Cancer Following Surgery for Rectal Cancer in Mismatch Repair Gene Mutation Carriers

Aung Ko Win, Susan Parry, Bryan Parry, Matthew F Kalady, Finlay A Macrae, Dennis J Ahnen, Graeme P Young, Lara Lipton, Ingrid Winship, Alex Boussioutas, Joanne P Young, Daniel D Buchanan, Julie Arnold, Loic Le Marchand, Polly A Newcomb, Robert W Haile, Noralane M Lindor, Steven Gallinger, John L Hopper, Mark A Jenkins

Journal article  |  2013  |  Annals of Surgical Oncology

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Colorectal carcinomas with KRAS mutation are associated with distinctive morphological and molecular features

Christophe Rosty, Joanne P Young, Michael D Walsh, Mark Clendenning, Rhiannon J Walters, Sally Pearson, Erika Pavluk, Belinda Nagler, David Pakenas, Jeremy R Jass, Mark A Jenkins, Aung Ko Win, Melissa C Southey, Susan Parry, John L Hopper, Graham G Giles, Elizabeth Williamson, Dallas R English, Daniel D Buchanan

Journal article  |  2013  |  Modern Pathology

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Cumulative impact of common genetic variants and other risk factors on colorectal cancer risk in 42 103 individuals

Malcolm G Dunlop, Albert Tenesa, Susan M Farrington, Stephane Ballereau, David H Brewster, Thibaud Koessler, Paul Pharoah, Clemens Schafmayer, Jochen Hampe, Henry Voelzke, Jenny Chang-Claude, Michael Hoffmeister, Hermann Brenner, Susanna von Holst, Simone Picelli, Annika Lindblom, Mark A Jenkins, John L Hopper, Graham Casey, David Duggan, et al.

Journal article  |  2013  |  Gut

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Absence of PMS2 mutations in colon-CFR participants whose colorectal cancers demonstrate unexplained loss of MLH1 expression

M Clendenning, FA Macrae, MD Walsh, RJ Walters, SN Thibodeau, SR Gunawardena, JD Potter, RW Haile, S Gallinger, JL Hopper, MA Jenkins, C Rosty, JP Young, DD Buchanan

Journal article  |  2013  |  Clinical Genetics

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Family History of Colorectal Cancer in BRAF p.V600E-Mutated Colorectal Cancer Cases

Daniel D Buchanan, Aung K Win, Michael D Walsh, Rhiannon J Walters, Mark Clendenning, Belinda Nagler, Sally-Ann Pearson, Finlay A Macrae, Susan Parry, Julie Arnold, Ingrid Winship, Graham G Giles, Noralane M Lindor, John D Potter, John L Hopper, Christophe Rosty, Joanne P Young, Mark A Jenkins

Journal article  |  2013  |  Cancer Epidemiology, Biomarkers & Prevention

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Screening Participation Predictors for People at Familial Risk of Colorectal Cancer A Systematic Review

Driss Ait Ouakrim, Trevor Lockett, Alex Boussioutas, Louise Keogh, Louisa B Flander, John L Hopper, Mark A Jenkins

Journal article  |  2013  |  American Journal of Preventive Medicine

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Are the common genetic variants associated with colorectal cancer risk for DNA mismatch repair gene mutation carriers?

Aung Ko Win, John L Hopper, Daniel D Buchanan, Joanne P Young, Albert Tenesa, James G Dowty, Graham G Giles, Jack Goldblatt, Ingrid Winship, Alex Boussioutas, Graeme P Young, Susan Parry, John A Baron, David Duggan, Steven Gallinger, Polly A Newcomb, Robert W Haile, Loic Le Marchand, Noralane M Lindor, Mark A Jenkins

Journal article  |  2013  |  European Journal of Cancer

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Genetic Variations in SMAD7 Are Associated with Colorectal Cancer Risk in the Colon Cancer Family Registry

Xuejuan Jiang, J Esteban Castelao, David Vandenberg, Angel Carracedo, Carmen M Redondo, David V Conti, Jesus P Paredes Cotore, John D Potter, Polly A Newcomb, Michael N Passarelli, Mark A Jenkins, John L Hopper, Steven Gallinger, Loic Le Marchand, Maria E Martinez, Dennis J Ahnen, John A Baron, Noralane M Lindor, Robert W Haile, Manuela Gago-Dominguez

Journal article  |  2013  |  PLoS One

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A variant in FTO shows association with melanoma risk not due to BMI

Mark M Iles, Matthew H Law, Simon N Stacey, Jiali Han, Shenying Fang, Ruth Pfeiffer, Mark Harland, Stuart MacGregor, John C Taylor, Katja K Aben, Lars A Akslen, Marie-Francoise Avril, Esther Azizi, Bert Bakker, Kristrun R Benediktsdottir, Wilma Bergman, Giovanna Bianchi Scarra, Kevin M Brown, Donato Calista, Valerie Chaudru, et al.

Journal article  |  2013  |  Nature Genetics

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Identification of Genetic Susceptibility Loci for Colorectal Tumors in a Genome-Wide Meta-analysis

Ulrike Peters, Shuo Jiao, Fredrick R Schumacher, Carolyn M Hutter, Aaron K Aragaki, John A Baron, Sonja I Berndt, Stephane Bezieau, Hermann Brenner, Katja Butterbach, Bette J Caan, Peter T Campbell, Christopher S Carlson, Graham Casey, Andrew T Chan, Jenny Chang-Claude, Stephen J Chanock, Lin S Chen, Gerhard A Coetzee, Simon G Coetzee, et al.

Journal article  |  2013  |  Gastroenterology

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Cancer Risks for MLH1 and MSH2 Mutation Carriers

James G Dowty, Aung K Win, Daniel D Buchanan, Noralane M Lindor, Finlay A Macrae, Mark Clendenning, Yoland C Antill, Stephen N Thibodeau, Graham Casey, Steve Gallinger, Loic Le Marchand, Polly A Newcomb, Robert W Haile, Graeme P Young, Paul A James, Graham G Giles, Shanaka R Gunawardena, Barbara A Leggett, Michael Gattas, Alex Boussioutas, et al.

Journal article  |  2013  |  Human Mutation

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Multiplicity and Molecular Heterogeneity of Colorectal Carcinomas in Individuals With Serrated Polyposis

Christophe Rosty, Michael D Walsh, Rhiannon J Walters, Mark Clendenning, Sally-Ann Pearson, Mark A Jenkins, Aung Ko Win, John L Hopper, Kevin Sweet, Wendy L Frankel, Melyssa Aronson, Steve Gallinger, Jack Goldblatt, Kathy Tucker, Sian Greening, Michael R Gattas, Sonja Woodall, Julie Arnold, Neal I Walker, Susan Parry, et al.

Journal article  |  2013  |  American Journal of Surgical Pathology

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Recurrent and founder mutations in the PMS2 gene

J Tomsic, L Senter, S Liyanarachchi, M Clendenning, CP Vaughn, MA Jenkins, JL Hopper, J Young, W Samowitz, A de la Chapelle

Journal article  |  2013  |  Clinical Genetics

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Population-Based Estimate of Prostate Cancer Risk for Carriers of the HOXB13 Missense Mutation G84E

Robert J MacInnis, Gianluca Severi, Laura Baglietto, James G Dowty, Mark A Jenkins, Melissa C Southey, John L Hopper, Graham G Giles

Journal article  |  2013  |  PLoS One

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Risks of Colorectal and Other Cancers After Endometrial Cancer for Women With Lynch Syndrome

Aung Ko Win, Noralane M Lindor, Ingrid Winship, Katherine M Tucker, Daniel D Buchanan, Joanne P Young, Christophe Rosty, Barbara Leggett, Graham G Giles, Jack Goldblatt, Finlay A Macrae, Susan Parry, Matthew F Kalady, John A Baron, Dennis J Ahnen, Loic Le Marchand, Steven Gallinger, Robert W Haile, Polly A Newcomb, John L Hopper, et al.

Journal article  |  2013  |  Journal of the National Cancer Institute

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Risk of breast cancer in Lynch syndrome: a systematic review

Aung Ko Win, Noralane M Lindor, Mark A Jenkins

Journal article  |  2013  |  Breast Cancer Research

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A Multifactorial Likelihood Model for MMR Gene Variant Classification Incorporating Probabilities Based on Sequence Bioinformatics and Tumor Characteristics: A Report from the Colon Cancer Family Registry

Bryony A Thompson, David E Goldgar, Carol Paterson, Mark Clendenning, Rhiannon Walters, Sven Arnold, Michael T Parsons, Michael D Walsh, Steven Gallinger, Robert W Haile, John L Hopper, Mark A Jenkins, Loic LeMarchand, Noralane M Lindor, Polly A Newcomb, Stephen N Thibodeau, Joanne P Young, Daniel D Buchanan, Sean V Tavtigian, Amanda B Spurdle

Journal article  |  2013  |  Human Mutation

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Genome-Wide Search for Gene-Gene Interactions in Colorectal Cancer

Shuo Jiao, Li Hsu, Sonja Berndt, Stephane Bezieau, Hermann Brenner, Daniel Buchanan, Bette J Caan, Peter T Campbell, Christopher S Carlson, Graham Casey, Andrew T Chan, Jenny Chang-Claude, Stephen Chanock, David V Conti, Keith R Curtis, David Duggan, Steven Gallinger, Stephen B Gruber, Tabitha A Harrison, Richard B Hayes, et al.

Journal article  |  2012  |  PLoS One

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Does eczema in infancy cause hay fever, asthma, or both in childhood? Insights from a novel regression model of sibling data

John L Hopper, Quang M Bui, Bircan Erbas, Melanie C Matheson, Lyle C Gurrin, John A Burgess, Adrian J Lowe, Mark A Jenkins, Michael J Abramson, E Haydn Walters, Graham G Giles, Shyamali C Dharmage

Journal article  |  2012  |  Journal of Allergy and Clinical Immunology

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Identification of Risk Genes through Whole Exome Sequencing in the Colon Cancer Family Registry

Melissa S DeRycke, Shanaka R Gunawardena, Shannon K McDonnell, Shaun M Riska, Yan W Asmann, Sumit Middha, Daniel J Schaid, Bruce W Eckloff, Stephen N Thibodeau, Noralane M Lindor, John L Hopper, Mark A Jenkins, Daniel D Buchanen, Michael Woods, Robert W Haile, Graham Casey, John A Baron, Steve Gallinger, Ellen L Goode

Conference Proceedings  |  2012  |  GENETIC EPIDEMIOLOGY

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Screening practices of Australian men and women categorized as "at or slightly above average risk" of colorectal cancer

Driss Ait Ouakrim, Trevor Lockett, Alex Boussioutas, Louise Keogh, Louisa B Flander, Ingrid Winship, Graham G Giles, John L Hopper, Mark A Jenkins

Journal article  |  2012  |  Cancer Causes & Control

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Identification of Lynch Syndrome Among Patients With Colorectal Cancer

Leticia Moreira, Francesc Balaguer, Noralane Lindor, Albert de la Chapelle, Heather Hampel, Lauri A Aaltonen, John L Hopper, Loic Le Marchand, Steven Gallinger, Polly A Newcomb, Robert Haile, Stephen N Thibodeau, Shanaka Gunawardena, Mark A Jenkins, Daniel D Buchanan, John D Potter, John A Baron, Dennis J Ahnen, Victor Moreno, Montserrat Andreu, et al.

Journal article  |  2012  |  JAMA: Journal of the American Medical Association

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Risks of Primary Extracolonic Cancers Following Colorectal Cancer in Lynch Syndrome

Aung Ko Win, Noralane M Lindor, Joanne P Young, Finlay A Macrae, Graeme P Young, Elizabeth Williamson, Susan Parry, Jack Goldblatt, Lara Lipton, Ingrid Winship, Barbara Leggett, Katherine M Tucker, Graham G Giles, Daniel D Buchanan, Mark Clendenning, Christophe Rosty, Julie Arnold, A Joan Levine, Robert W Haile, Steven Gallinger, et al.

Journal article  |  2012  |  Journal of the National Cancer Institute

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Reasons for ongoing participation in a longitudinal cohort study

Christopher A Barton, Cathryn May, Desiree Meszaros, Melanie C Matheson, Mark Jenkins, Graham Giles, John Hopper, E Haydn Walters, Shyamali C Dharmage, Michael J Abramson

Journal article  |  2012  |  Australian and New Zealand Journal of Public Health

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MC1R genotypes and risk of melanoma before age 40 years: A population-based case-control-family study

Anne E Cust, Chris Goumas, Elizabeth A Holland, Chantelle Agha-Hamilton, Joanne F Aitken, Bruce K Armstrong, Graham G Giles, Richard F Kefford, Helen Schmid, John L Hopper, Graham J Mann, Mark A Jenkins

Journal article  |  2012  |  International Journal of Cancer

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Body size and risk for colorectal cancers showing BRAF mutations or microsatellite instability: a pooled analysis

Laura AE Hughes, Elizabeth J Williamson, Manon van Engeland, Mark A Jenkins, Graham G Giles, John L Hopper, Melissa C Southey, Joanne P Young, Daniel D Buchanan, Michael D Walsh, Piet A van den Brandt, R Alexandra Goldbohm, Matty P Weijenberg, Dallas R English

Journal article  |  2012  |  International Journal of Epidemiology

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Performance of PREM1,2,6, MMRpredict, and MMRpro in detecting Lynch syndrome among endometrial cancer cases

Rowena C Mercado, Heather Hampel, Fay Kastrinos, Ewout Steyerberg, Judith Balmana, Elena Stoffel, David E Cohn, Floor J Backes, John L Hopper, Mark A Jenkins, Noralane M Lindor, Graham Casey, Robert Haile, Subha Madhavan, Albert de la Chapelle, Sapna Syngal

Journal article  |  2012  |  Genetics in Medicine

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Common variation near CDKN1A, POLD3 and SHROOM2 influences colorectal cancer risk

Malcolm G Dunlop, Sara E Dobbins, Susan Mary Farrington, Angela M Jones, Claire Palles, Nicola Whiffin, Albert Tenesa, Sarah Spain, Peter Broderick, Li-Yin Ooi, Enric Domingo, Claire Smillie, Marc Henrion, Matthew Frampton, Lynn Martin, Graeme Grimes, Maggie Gorman, Colin Semple, Yusanne P Ma, Ella Barclay, et al.

Journal article  |  2012  |  Nature Genetics

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Phenotype and Polyp Landscape in Serrated Polyposis Syndrome: A Series of 100 Patients From Genetics Clinics

Christophe Rosty, Daniel D Buchanan, Michael D Walsh, Sally-Ann Pearson, Erika Pavluk, Rhiannon J Walters, Mark Clendenning, Kevin J Spring, Mark A Jenkins, Aung K Win, John L Hopper, Kevin Sweet, Wendy L Frankel, Melyssa Aronson, Steve Gallinger, Jack Goldblatt, Sonja Woodall, Julie Arnold, Neal I Walker, Jeremy R Jass, et al.

Journal article  |  2012  |  American Journal of Surgical Pathology

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Colorectal Cancer Linkage on Chromosomes 4q21, 8q13, 12q24, and 15q22

Mine S Cicek, Julie M Cunningham, Brooke L Fridley, Daniel J Serie, William R Bamlet, Brenda Diergaarde, Robert W Haile, Loic Le Marchand, Theodore G Krontiris, H Banfield Younghusband, Steven Gallinger, Polly A Newcomb, John L Hopper, Mark A Jenkins, Graham Casey, Fredrick Schumacher, Zhu Chen, Melissa S DeRycke, Allyson S Templeton, Ingrid Winship, et al.

Journal article  |  2012  |  PLoS One

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Kaplan-Meier failure estimate for metachronous colorectal cancer risk is clinically relevant

Mark A Jenkins, Lyle C Gurrin, Susan Parry, Aung Ko Win

Journal article  |  2012  |  Gut

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Immunohistochemical testing of conventional adenomas for loss of expression of mismatch repair proteins in Lynch syndrome mutation carriers: a case series from the Australasian site of the colon cancer family registry

Michael D Walsh, Daniel D Buchanan, Sally-Ann Pearson, Mark Clendenning, Mark A Jenkins, Aung Ko Win, Rhiannon J Walters, Kevin J Spring, Belinda Nagler, Erika Pavluk, Sven T Arnold, Jack Goldblatt, Jill George, Graeme K Suthers, Kerry Phillips, John L Hopper, Jeremy R Jass, John A Baron, Dennis J Ahnen, Stephen N Thibodeau, et al.

Journal article  |  2012  |  Modern Pathology

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Cancer Risks for Relatives of Patients With Serrated Polyposis

Aung Ko Win, Rhiannon J Walters, Daniel D Buchanan, Mark A Jenkins, Kevin Sweet, Wendy L Frankel, Albert de la Chapelle, Diane M McKeone, Michael D Walsh, Mark Clendenning, Sally-Ann Pearson, Erika Pavluk, Belinda Nagler, John L Hopper, Michael R Gattas, Jack Goldblatt, Jill George, Graeme K Suthers, Kerry D Phillips, Sonja Woodall, et al.

Journal article  |  2012  |  American Journal of Gastroenterology

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Role of Environmental Risk Factors on Early-Onset Colorectal Cancer Risk

Aung Ko Win, Sergio A Taunde, Joanne P Young, Daniel D Buchanan, Driss Ait Ouakrim, Noralane M Lindor, Loic Le Marchand, Steven Gallinger, Michelle Cotterchio, Polly A Newcomb, Robert W Haile, John Hopper, Mark A Jenkins

Conference Proceedings  |  2012  |  GASTROENTEROLOGY

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Colorectal and Other Cancer Risks for Carriers and Noncarriers From Families With a DNA Mismatch Repair Gene Mutation: A Prospective Cohort Study

Aung Ko Win, Joanne P Young, Noralane M Lindor, Katherine M Tucker, Dennis J Ahnen, Graeme P Young, Daniel D Buchanan, Mark Clendenning, Graham G Giles, Ingrid Winship, Finlay A Macrae, Jack Goldblatt, Melissa C Southey, Julie Arnold, Stephen N Thibodeau, Shanaka R Gunawardena, Bharati Bapat, John A Baron, Graham Casey, Steven Gallinger, et al.

Journal article  |  2012  |  Journal of Clinical Oncology

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Risk Prediction Models for Colorectal Cancer: A Review

Aung Ko Win, Robert J MacInnis, John L Hopper, Mark A Jenkins

Journal article  |  2012  |  Cancer Epidemiology, Biomarkers & Prevention

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Meta-Analysis Combining New and Existing Data Sets Confirms that the TERT-CLPTM1L Locus Influences Melanoma Risk

Matthew H Law, Grant W Montgomery, Kevin M Brown, Nicholas G Martin, Graham J Mann, Nicholas K Hayward, Stuart MacGregor

Journal article  |  2012  |  Journal of Investigative Dermatology

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Meta-analysis of new genome-wide association studies of colorectal cancer risk

Ulrike Peters, Carolyn M Hutter, Li Hsu, Fredrick R Schumacher, David V Conti, Christopher S Carlson, Christopher K Edlund, Robert W Haile, Steven Gallinger, Brent W Zanke, Mathieu Lemire, Jagadish Rangrej, Raakhee Vijayaraghavan, Andrew T Chan, Aditi Hazra, David J Hunter, Jing Ma, Charles S Fuchs, Edward L Giovannucci, Peter Kraft, et al.

Journal article  |  2012  |  Human Genetics

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Cancer Risks for the Relatives of Colorectal Cancer Cases with a Methylated MLH1 Promoter Region: Data from the Colorectal Cancer Family Registry

A Joan Levine, Aung Ko Win, Daniel D Buchanan, Mark A Jenkins, John A Baron, Joanne P Young, Tiffany I Long, Daniel J Weisenberger, Peter W Laird, Rebecca L McCall, David J Duggan, Robert W Haile

Journal article  |  2012  |  Cancer prevention research

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Using tumour pathology to identify people at high genetic risk of breast and colorectal cancers

JL Hopper, MA Jenkins, JG Dowty, GS Dite, C Apicella, L Keogh, AK Win, JP Young, D Buchanan, MD Walsh, C Rosty, L Baglietto, G Severi, KA Phillips, EM Wong, A Dobrovic, P Waring, I Winship, SJ Ramus, GG Giles, et al.

Journal article  |  2012  |  Pathology

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Screening Practices of Unaffected People at Familial Risk of Colorectal Cancer

Driss Ait Ouakrim, Alex Boussioutas, Trevor Lockett, Ingrid Winship, Graham G Giles, Louisa B Flander, Louise Keogh, John L Hopper, Mark A Jenkins

Journal article  |  2012  |  Cancer prevention research

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Pathway-Based Analysis of a Melanoma Genome-Wide Association Study: Analysis of Genes Related to Tumour-Immunosuppression

Nils Schoof, Mark M Iles, D Timothy Bishop, Julia A Newton-Bishop, Jennifer H Barrett

Journal article  |  2011  |  PLoS One

Systemic immunosuppression is a risk factor for melanoma, and sunburn-induced immunosuppression is thought to be causal. Genes in ..

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Genome-wide association study identifies novel loci predisposing to cutaneous melanoma

Christopher I Amos, Li-E Wang, Jeffrey E Lee, Jeffrey E Gershenwald, Wei V Chen, Shenying Fang, Roman Kosoy, Mingfeng Zhang, Abrar A Qureshi, Selina Vattathil, Christopher W Schacherer, Julie M Gardner, Yuling Wang, D Tim Bishop, Jennifer H Barrett, Stuart MacGregor, Nicholas K Hayward, Nicholas G Martin, David L Duffy, Graham J Mann, et al.

Journal article  |  2011  |  Human Molecular Genetics

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Meta-analysis of 8q24 for seven cancers reveals a locus between NOV and ENPP2 associated with cancer development

Abra G Brisbin, Yan W Asmann, Honglin Song, Ya-Yu Tsai, Jeremiah A Aakre, Ping Yang, Robert B Jenkins, Paul Pharoah, Fredrick Schumacher, David V Conti, David J Duggan, Mark Jenkins, John Hopper, Steven Gallinger, Polly Newcomb, Graham Casey, Thomas A Sellers, Brooke L Fridley

Journal article  |  2011  |  BMC Medical Genetics

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A novel recurrent mutation in MITF predisposes to familial and sporadic melanoma

Satoru Yokoyama, Susan L Woods, Glen M Boyle, Lauren G Aoude, Stuart MacGregor, Victoria Zismann, Michael Gartside, Anne E Cust, Rizwan Haq, Mark Harland, John C Taylor, David L Duffy, Kelly Holohan, Ken Dutton-Regester, Jane M Palmer, Vanessa Bonazzi, Mitchell S Stark, Judith Symmons, Matthew H Law, Christopher Schmidt, et al.

Journal article  |  2011  |  Nature

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Cancer risks for monoallelic MUTYH mutation carriers with a family history of colorectal cancer

Aung Ko Win, Sean P Cleary, James G Dowty, John A Baron, Joanne P Young, Daniel D Buchanan, Melissa C Southey, Terrilea Burnett, Patrick S Parfrey, Roger C Green, Loic Le Marchand, Polly A Newcomb, Robert W Haile, Noralane M Lindor, John L Hopper, Steven Gallinger, Mark A Jenkins

Journal article  |  2011  |  International Journal of Cancer

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Genome-wide association study identifies a new melanoma susceptibility locus at 1q21.3

Stuart MacGregor, Grant W Montgomery, Jimmy Z Liu, Zhen Zhen Zhao, Anjali K Henders, Mitchell Stark, Helen Schmid, Elizabeth A Holland, David L Duffy, Mingfeng Zhang, Jodie N Painter, Dale R Nyholt, Judith A Maskiell, Jodie Jetann, Megan Ferguson, Anne E Cust, Mark A Jenkins, David C Whiteman, Hakan Olsson, Susana Puig, et al.

Journal article  |  2011  |  Nature Genetics

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Genome-wide association study identifies three new melanoma susceptibility loci

Jennifer H Barrett, Mark M Iles, Mark Harland, John C Taylor, Joanne F Aitken, Per Arne Andresen, Lars A Akslen, Bruce K Armstrong, Marie-Francoise Avril, Esther Azizi, Bert Bakker, Wilma Bergman, Giovanna Bianchi-Scarra, Brigitte Bressac-de Paillerets, Donato Calista, Lisa A Cannon-Albright, Eve Corda, Anne E Cust, Tadeusz Debniak, David Duffy, et al.

Journal article  |  2011  |  Nature Genetics

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Identification of IL6R and chromosome 11q13.5 as risk loci for asthma

Manuel AR Ferreira, Melanie C Matheson, David L Duffy, Guy B Marks, Jennie Hui, Peter Le Souef, Patrick Danoy, Svetlana Baltic, Dale R Nyholt, Mark Jenkins, Catherine Hayden, Gonneke Willemsen, Wei Ang, Mikko Kuokkanen, John Beilby, Faang Cheah, Eco JC de Geus, Adaikalavan Ramasamy, Sailaja Vedantam, Veikko Salomaa, et al.

Journal article  |  2011  |  The Lancet

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Adequacy of risk-reducing gynaecologic surgery in BRCA1 or BRCA2 mutation carriers and other women at high risk of pelvic serous cancer

BE Kiely, ML Friedlander, RL Milne, L Stanhope, P Russell, MA Jenkins, P Weideman, SA McLachlan, P Grant, JL Hopper, KA Phillips

Journal article  |  2011  |  Familial Cancer

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Determining the frequency of de novo germline mutations in DNA mismatch repair genes

Aung Ko Win, Mark A Jenkins, Daniel D Buchanan, Mark Clendenning, Joanne P Young, Graham G Giles, Jack Goldblatt, Barbara A Leggett, John L Hopper, Stephen N Thibodeau, Noralane M Lindor

Journal article  |  2011  |  Journal of Medical Genetics

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Estimates of familial risks from family data are biased when ascertainment of families is not independent of family history

Aung Ko Win, John L Hopper, Mark A Jenkins

Journal article  |  2011  |  Gut

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Fine-mapping of colorectal cancer susceptibility loci at 8q23.3, 16q22.1 and 19q13.11: refinement of association signals and use of in silico analysis to suggest functional variation and unexpected candidate target genes

Luis G Carvajal-Carmona, Jean-Baptiste Cazier, Angela M Jones, Kimberley Howarth, Peter Broderick, Alan Pittman, Sara Dobbins, Albert Tenesa, Susan Farrington, James Prendergast, Evi Theodoratou, Rebecca Barnetson, David Conti, Polly Newcomb, John L Hopper, Mark A Jenkins, Steven Gallinger, David J Duggan, Harry Campbell, David Kerr, et al.

Journal article  |  2011  |  Human Molecular Genetics

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Image-guided sampling reveals increased stroma and lower glandular complexity in mammographically dense breast tissue

Suling J Lin, Jennifer Cawson, Prue Hill, Izhak Haviv, Mark Jenkins, John L Hopper, Melissa C Southey, Ian G Campbell, Erik W Thompson

Journal article  |  2011  |  Breast Cancer Research and Treatment

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Metachronous colorectal cancer risk for mismatch repair gene mutation carriers: the advantage of more extensive colon surgery

Susan Parry, Aung Ko Win, Bryan Parry, Finlay A Macrae, Lyle C Gurrin, James M Church, John A Baron, Graham G Giles, Barbara A Leggett, Ingrid Winship, Lara Lipton, Graeme P Young, Joanne P Young, Caroline J Lodge, Melissa C Southey, Polly A Newcomb, Loic Le Marchand, Robert W Haile, Noralane M Lindor, Steven Gallinger, et al.

Journal article  |  2011  |  Gut

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Body mass index in early adulthood and colorectal cancer risk for carriers and non-carriers of germline mutations in DNA mismatch repair genes

AK Win, JG Dowty, DR English, PT Campbell, JP Young, I Winship, FA Macrae, L Lipton, S Parry, GP Young, DD Buchanan, ME Martinez, ET Jacobs, DJ Ahnen, RW Haile, G Casey, JA Baron, NM Lindor, SN Thibodeau, PA Newcomb, et al.

Journal article  |  2011  |  British Journal of Cancer

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Multiple Common Susceptibility Variants near BMP Pathway Loci GREM1, BMP4, and BMP2 Explain Part of the Missing Heritability of Colorectal Cancer

Ian PM Tomlinson, Luis G Carvajal-Carmona, Sara E Dobbins, Albert Tenesa, Angela M Jones, Kimberley Howarth, Claire Palles, Peter Broderick, Emma EM Jaeger, Susan Farrington, Annabelle Lewis, James GD Prendergast, Alan M Pittman, Evropi Theodoratou, Bianca Olver, Marion Walker, Steven Penegar, Ella Barclay, Nicola Whiffin, Lynn Martin, et al.

Journal article  |  2011  |  PLoS Genetics

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Mutation deep within an intron of MSH2 causes Lynch syndrome

Mark Clendenning, Daniel D Buchanan, Michael D Walsh, Belinda Nagler, Christophe Rosty, Bryony Thompson, Amanda B Spurdle, John L Hopper, Mark A Jenkins, Joanne P Young

Journal article  |  2011  |  Familial Cancer

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Linkage to chromosome 2q32.2-q33.3 in familial serrated neoplasia (Jass syndrome)

Aedan Roberts, Derek Nancarrow, Mark Clendenning, Daniel D Buchanan, Mark A Jenkins, David Duggan, Darin Taverna, Diane McKeone, Rhiannon Walters, Michael D Walsh, Bruce W Young, Jeremy R Jass, Christophe Rosty, Michael Gattas, Elise Pelzer, John L Hopper, Jack Goldblatt, Jill George, Graeme K Suthers, Kerry Phillips, et al.

Journal article  |  2011  |  Familial Cancer

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Early-life sun exposure and risk of melanoma before age 40 years

Anne E Cust, Mark A Jenkins, Chris Goumas, Bruce K Armstrong, Helen Schmid, Joanne F Aitken, Graham G Giles, Richard F Kefford, John L Hopper, Graham J Mann

Journal article  |  2011  |  Cancer Causes & Control

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Factors influencing asthma remission: a longitudinal study from childhood to middle age

John A Burgess, Melanie C Matheson, Lyle C Gurrin, Graham B Byrnes, Kristie S Adams, Cathryn L Wharton, Graham G Giles, Mark A Jenkins, John L Hopper, Michael J Abramson, E Haydn Walters, Shyamali C Dharmage

Journal article  |  2011  |  Thorax

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Quality Assessment and Correlation of Microsatellite Instability and Immunohistochemical Markers among Population- and Clinic-Based Colorectal Tumors Results from the Colon Cancer Family Registry

Mine S Cicek, Noralane M Lindor, Steven Gallinger, Bharati Bapat, John L Hopper, Mark A Jenkins, Joanne Young, Daniel Buchanan, Michael D Walsh, Loic Le Marchand, Terrilea Burnett, Polly A Newcomb, William M Grady, Robert W Haile, Graham Casey, Sarah J Plummer, Lisa A Krumroy, John A Baron, Stephen N Thibodeau

Journal article  |  2011  |  Journal of Molecular Diagnostics

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Genotype-Environment Interactions in Microsatellite Stable/Microsatellite Instability-Low Colorectal Cancer: Results from a Genome-Wide Association Study

Jane C Figueiredo, Juan Pablo Lewinger, Chi Song, Peter T Campbell, David V Conti, Christopher K Edlund, Dave J Duggan, Jagadish Rangrej, Mathieu Lemire, Thomas Hudson, Brent Zanke, Michelle Cotterchio, Steven Gallinger, Mark Jenkins, John Hopper, Robert Haile, Polly Newcomb, John Potter, John A Baron, Loic Le Marchand, et al.

Journal article  |  2011  |  Cancer Epidemiology, Biomarkers & Prevention

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Sunbed use during adolescence and early adulthood is associated with increased risk of early-onset melanoma

Anne E Cust, Bruce K Armstrong, Chris Goumas, Mark A Jenkins, Helen Schmid, John L Hopper, Richard F Kefford, Graham G Giles, Joanne F Aitken, Graham J Mann

Journal article  |  2011  |  International Journal of Cancer

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Body Mass Index in Early Adulthood and Endometrial Cancer Risk for Mismatch Repair Gene Mutation Carriers

Aung Ko Win, James G Dowty, Yoland C Antill, Dallas R English, John A Baron, Joanne P Young, Graham G Giles, Melissa C Southey, Ingrid Winship, Lara Lipton, Susan Parry, Stephen N Thibodeau, Robert W Haile, Steven Gallinger, Loic Le Marchand, Noralane M Lindor, Polly A Newcomb, John L Hopper, Mark A Jenkins

Journal article  |  2011  |  Obstetrics and Gynecology

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Melanoma risk for CDKN2A mutation carriers who are relatives of population-based case carriers in Australia and the UK

Anne E Cust, Mark Harland, Enes Makalic, Daniel Schmidt, James G Dowty, Joanne F Aitken, Chantelle Agha-Hamilton, Bruce K Armstrong, Jenny H Barrett, May Chan, Yu-Mei Chang, Joanne Gascoyne, Graham G Giles, Elizabeth A Holland, Richard F Kefford, Kairen Kukalizch, Johanna Lowery, Juliette A Randerson-Moor, Helen Schmid, Claire F Taylor, et al.

Journal article  |  2011  |  Journal of Medical Genetics

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Morphological predictors of BRCA1 germline mutations in young women with breast cancer

MC Southey, SJ Ramus, JG Dowty, LD Smith, AA Tesoriero, EEM Wong, GS Dite, MA Jenkins, GB Byrnes, I Winship, K-A Phillips, GG Giles, JL Hopper

Journal article  |  2011  |  British Journal of Cancer

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Association between monoallelic MUTYH mutation and colorectal cancer risk: a meta-regression analysis

Aung Ko Win, John L Hopper, Mark A Jenkins

Journal article  |  2011  |  Familial Cancer

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Investigating the Potential Role of Genetic and Epigenetic Variation of DNA Methyltransferase Genes in Hyperplastic Polyposis Syndrome

Musa Drini, Nicholas C Wong, Hamish S Scott, Jeffrey M Craig, Alexander Dobrovic, Chelsee A Hewitt, Christofer Dow, Joanne P Young, Mark A Jenkins, Richard Saffery, Finlay A Macrae

Journal article  |  2011  |  PLoS One

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Dependence of Colorectal Cancer Risk on the Parent-of-Origin of Mutations in DNA Mismatch Repair Genes

Christine M van Vliet, James G Dowty, Jane L van Vliet, Letitia Smith, Leeanne J Mead, Finlay A Macrae, D James B St John, Graham G Giles, Melissa C Southey, Mark A Jenkins, Gary M Velan, John L Hopper

Journal article  |  2011  |  Human Mutation

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Genetic Variation at 9p22.2 and Ovarian Cancer Risk for BRCA1 and BRCA2 Mutation Carriers

Susan J Ramus, Christiana Kartsonaki, Simon A Gayther, Paul DP Pharoah, Olga M Sinilnikova, Jonathan Beesley, Xiaoqing Chen, Lesley McGuffog, Sue Healey, Fergus J Couch, Xianshu Wang, Zachary Fredericksen, Paolo Peterlongo, Siranoush Manoukian, Bernard Peissel, Daniela Zaffaroni, Gaia Roversi, Monica Barile, Alessandra Viel, Anna Allavena, et al.

Journal article  |  2011  |  Journal of the National Cancer Institute

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Constitutional Methylation of the BRCA1 Promoter Is Specifically Associated with BRCA1 Mutation-Associated Pathology in Early-Onset Breast Cancer

Ee Ming Wong, Melissa C Southey, Stephen B Fox, Melissa A Brown, James G Dowty, Mark A Jenkins, Graham G Giles, John L Hopper, Alexander Dobrovic

Journal article  |  2011  |  Cancer prevention research

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The PREMM1,2,6 Model Predicts Risk of MLH1, MSH2, and MSH6 Germline Mutations Based on Cancer History

Fay Kastrinos, Ewout W Steyerberg, Rowena Mercado, Judith Balmana, Spring Holter, Steven Gallinger, Kimberly D Siegmund, James M Church, Mark A Jenkins, Noralane M Lindor, Stephen N Thibodeau, Lynn Anne Burbidge, Richard J Wenstrup, Sapna Syngal

Journal article  |  2011  |  Gastroenterology

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Frequency of Deletions of EPCAM (TACSTD1) in MSH2-Associated Lynch Syndrome Cases

Kandelaria Rumilla, Karen V Schowalter, Noralane M Lindor, Brittany C Thomas, Kara A Mensink, Steven Gallinger, Spring Holter, Polly A Newcomb, John D Potter, Mark A Jenkins, John L Hopper, Tiffany I Long, Daniel J Weisenberger, Robert W Haile, Graham Casey, Peter W Laird, Loic Le Marchand, Stephen N Thibodeau

Journal article  |  2011  |  Journal of Molecular Diagnostics

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A large-scale meta-analysis to refine colorectal cancer risk estimates associated with MUTYH variants

E Theodoratou, H Campbell, A Tenesa, R Houlston, E Webb, S Lubbe, P Broderick, S Gallinger, EM Croitoru, MA Jenkins, AK Win, SP Cleary, T Koessler, PD Pharoah, S Kuery, S Bezieau, B Buecher, NA Ellis, P Peterlongo, K Offit, et al.

Journal article  |  2010  |  British Journal of Cancer

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Risk of endometrial cancer for women diagnosed with HNPCC-related colorectal carcinoma

Andreas Obermair, Danny R Youlden, Joanne P Young, Noralane M Lindor, John A Baron, Polly Newcomb, Susan Parry, John L Hopper, Robert Haile, Mark A Jenkins

Journal article  |  2010  |  International Journal of Cancer

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Linkage to chromosome 2q32.2-q35 in familial serrated neoplasia

A Roberts, D Nancarrow, M Clendenning, DD Buchanan, MA Jenkins, D Duggan, MD Walsh, S Parry, A Lindblom, JP Young

Conference Proceedings  |  2010  |  JOURNAL OF GASTROENTEROLOGY AND HEPATOLOGY

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Asthma, Asthma Medications, and Prostate Cancer Risk

Gianluca Severi, Laura Baglietto, David C Muller, Dallas R English, Mark A Jenkins, Michael J Abramson, Jo A Douglass, John L Hopper, Graham G Giles

Journal article  |  2010  |  Cancer Epidemiology, Biomarkers & Prevention

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Use of Folic Acid-Containing Supplements after a Diagnosis of Colorectal Cancer in the Colon Cancer Family Registry

Rebecca S Holmes, Yingye Zheng, John A Baron, Lin Li, Gail McKeown-Eyssen, Polly A Newcomb, Mariana C Stern, Robert W Haile, William M Grady, John D Potter, Loic Le Marchand, Peter T Campbell, Jane C Figueiredo, Paul J Limburg, Mark A Jenkins, John L Hopper, Cornelia M Ulrich

Journal article  |  2010  |  Cancer Epidemiology, Biomarkers & Prevention

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Hospital-admitted eye injury in Victoria, Australia

Simon Raymond, Mark Jenkins, Ian Favilla, Dylan Rajeswaran

Journal article  |  2010  |  Clinical and Experimental Ophthalmology

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Risk Factors for Colorectal Cancer in Patients with Multiple Serrated Polyps: A Cross-Sectional Case Series from Genetics Clinics

Daniel D Buchanan, Kevin Sweet, Musa Drini, Mark A Jenkins, Aung Ko Win, Dallas R English, Michael D Walsh, Mark Clendenning, Diane M McKeone, Rhiannon J Walters, Aedan Roberts, Sally-Ann Pearson, Erika Pavluk, John L Hopper, Michael R Gattas, Jack Goldblatt, Jill George, Graeme K Suthers, Kerry D Phillips, Sonja Woodall, et al.

Journal article  |  2010  |  PLoS One

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Parent of origin effects on age at colorectal cancer diagnosis

Noralane M Lindor, Karl G Rabe, Gloria M Petersen, Helen Chen, Bharati Bapat, John Hopper, Joanne Young, Mark Jenkins, John Potter, Polly Newcomb, Allyson Templeton, Loic LeMarchand, John Grove, Michael R Burgio, Robert Haile, Jane Green, Michael O Woods, Daniela Seminara, Paul J Limburg, Stephen N Thibodeau

Journal article  |  2010  |  International Journal of Cancer

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Confirmation of Linkage to and Localization of Familial Colon Cancer Risk Haplotype on Chromosome 9q22

Courtney Gray-McGuire, Kishore Guda, Indra Adrianto, Chee Paul Lin, Leanna Natale, John D Potter, Polly Newcomb, Elizabeth M Poole, Cornelia M Ulrich, Noralane Lindor, Ellen L Goode, Brooke L Fridley, Robert Jenkins, Loic Le Marchand, Graham Casey, Robert Haile, John Hopper, Mark Jenkins, Joanne Young, Daniel Buchanan, et al.

Journal article  |  2010  |  Cancer Research

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Letter in response to "Identifying Lynch syndrome" by de la Chapelle et al.

Mark A Jenkins, James G Dowty, John L Hopper, Kathy Tucker, Melissa C Southey

Journal article  |  2010  |  International Journal of Cancer

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Phenotypic diversity in patients with multiple serrated polyps: a genetics clinic study

Daniel D Buchanan, Kevin Sweet, Musa Drini, Mark A Jenkins, Aung Ko Win, Michael Gattas, Michael D Walsh, Mark Clendenning, Diane McKeone, Rhiannon Walters, Aedan Roberts, Alasdair Young, Heather Hampel, John L Hopper, Jack Goldblatt, Jill George, Graeme K Suthers, Kerry Phillips, Graeme P Young, Elizabeth Chow, et al.

Journal article  |  2010  |  International Journal of Colorectal Disease

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Over-Expression of the Chromosome 11 Mucins is Associated With CIMP and BRAF Mutation in Colorectal Cancer

Michael D Walsh, Daniel D Buchanan, Sally-Ann Pearson, Rhiannon J Walters, Diane M McKeone, Mark Clendenning, John Hopper, Mark A Jenkins, Graham G Giles, Dallas English, Christophe Rosty, Michael A McGuckin, Joanne P Young

Conference Proceedings  |  2010  |  GASTROENTEROLOGY

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Sex-Related Effects of Smoking in Patients With Multiple Serrated Polyps of the Colorectum

Michael D Walsh, Kevin Sweet, Musa Drini, Aung Ko Win, Daniel D Buchanan, Diane M McKeone, Mark A Jenkins, Sonja Woodall, Finlay A Macrae, Susan Parry, Joanne P Young

Conference Proceedings  |  2010  |  GASTROENTEROLOGY

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Contralateral risk-reducing mastectomy in BRCA1 and BRCA2 mutation carriers and other high-risk women in the Kathleen Cuningham Foundation Consortium for Research into Familial Breast Cancer (kConFab)

Belinda E Kiely, Mark A Jenkins, Joanne M McKinley, Michael L Friedlander, Prue Weideman, Roger L Milne, Sue-Anne McLachlan, John L Hopper, Kelly-Anne Phillips

Journal article  |  2010  |  Breast Cancer Research and Treatment

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Erratum: Contralateral risk-reducing mastectomy in BRCA1 and BRCA2 mutation carriers and other high-risk women in the kathleen cuningham foundation consortium for research into familial breast cancer (kConFab) (Breast Cancer Res Treat (2010) (120) DOI: 10.1007/s10549-009-0497-8))

BE Kiely, MA Jenkins, JM McKinley, ML Friedlander, P Weideman, RL Milne, SA McLachlan, JL Hopper, KA Phillips

Journal article  |  2010  |  Breast Cancer Research and Treatment

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Lynch Syndrome-Associated Breast Cancers: Clinicopathologic Characteristics of a Case Series from the Colon Cancer Family Registry

Michael D Walsh, Daniel D Buchanan, Margaret C Cummings, Sally-Ann Pearson, Sven T Arnold, Mark Clendenning, Rhiannon Walters, Diane M McKeone, Amanda B Spurdle, John L Hopper, Mark A Jenkins, Kerry D Phillips, Graeme K Suthers, Jill George, Jack Goldblatt, Amanda Muir, Kathy Tucker, Elise Pelzer, Michael R Gattas, Sonja Woodall, et al.

Journal article  |  2010  |  Clinical Cancer Research

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Lynch syndrome-associated breast cancers: Clinicopathological characteristics of a case series from the Colon CFR

Christophe Rosty, Michael Walsh, Margaret Cummings, Daniel Buchanan, Sven Arnold, Diane McKeone, Rhiannon Walters, John Hopper, Mark Jenkins, Amanda Spurdle, Michael McGuckin, Sunil Lakhani, Joanne Young

Conference Proceedings  |  2010  |  Carcinogenesis

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Genes involved with folate uptake and distribution and their association with colorectal cancer risk

Jane C Figueiredo, A Joan Levine, Won H Lee, David V Conti, Jenny N Poynter, Peter T Campbell, David Duggan, Juan Pablo Lewinger, Maria Elena Martinez, Cornelia M Ulrich, Polly Newcomb, John Potter, Paul J Limburg, John Hopper, Mark A Jenkins, Loic Le Marchand, John A Baron, Robert W Haile

Journal article  |  2010  |  Cancer Causes & Control

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Case-Control Study of Overweight, Obesity, and Colorectal Cancer Risk, Overall and by Tumor Microsatellite Instability Status

Peter T Campbell, Elizabeth T Jacobs, Cornelia M Ulrich, Jane C Figueiredo, Jenny N Poynter, John R McLaughlin, Robert W Haile, Eric J Jacobs, Polly A Newcomb, John D Potter, Loic Le Marchand, Roger C Green, Patrick Parfrey, H Banfield Younghusband, Michelle Cotterchio, Steven Gallinger, Mark A Jenkins, John L Hopper, John A Baron, Stephen N Thibodeau, et al.

Journal article  |  2010  |  Journal of the National Cancer Institute

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Childhood immunization and atopic disease into middle-age - a prospective cohort study

Melanie C Matheson, E Haydn Walters, John A Burgess, Mark A Jenkins, Graham G Giles, John L Hopper, Michael J Abramson, Shyamali C Dharmage

Journal article  |  2010  |  Pediatric Allergy and Immunology

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The role of SMAD4 in early-onset colorectal cancer

SG Royce, K Alsop, A Haydon, L Mead, LD Smith, AA Tesoriero, GG Giles, MA Jenkins, JL Hopper, MC Southey

Journal article  |  2010  |  Colorectal Disease

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Risk of endometrial cancer for women diagnosed with Lynch syndrome-related colorectal carcinoma

A Obermair, D Youlden, J Young, N Lindor, J Baron, P Newcomb, S Parry, J Hopper, R Haile, M Jenkins

Conference Proceedings  |  2010  |  GYNECOLOGIC ONCOLOGY

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Smoking and Colorectal Cancer in Lynch Syndrome: Results from the Colon Cancer Family Registry and The University of Texas MD Anderson Cancer Center

Mala Pande, Patrick M Lynch, John L Hopper, Mark A Jenkins, Steve Gallinger, Robert W Haile, Loic LeMarchand, Noralane M Lindor, Peter T Campbell, Polly A Newcomb, John D Potter, John A Baron, Marsha L Frazier, Christopher I Amos

Journal article  |  2010  |  Clinical Cancer Research

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Risks of Lynch Syndrome Cancers for MSH6 Mutation Carriers

Laura Baglietto, Noralane M Lindor, James G Dowty, Darren M White, Anja Wagner, Encarna B Gomez Garcia, Annette HJT Vriends, Nicola R Cartwright, Rebecca A Barnetson, Susan M Farrington, Albert Tenesa, Heather Hampel, Daniel Buchanan, Sven Arnold, Joanne Young, Michael D Walsh, Jeremy Jass, Finlay Macrae, Yoland Antill, Ingrid M Winship, et al.

Journal article  |  2010  |  Journal of the National Cancer Institute

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Alpha-1-antitrypsin deficiency and smoking as risk factors for mismatch repair deficient colorectal cancer: A study from the colon cancer family registry

Noralane M Lindor, Ping Yang, Ilonka Evans, Karen Schowalter, Mariza De Andrade, Jia Li, Elysia Jeavons, Gloria Peterson, Steve Gallinger, Bharati Bapat, John Hopper, Jeremy Jass, Mark Jenkins, Allyson Templeton, John Potter, Polly A Newcomb, Loic LeMarchand, John Grove, Robert Haile, John Baron, et al.

Journal article  |  2010  |  Molecular Genetics and Metabolism

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Genetic Variation in the Vitamin D Receptor (VDR) and the Vitamin D-Binding Protein (GC) and Risk for Colorectal Cancer: Results from the Colon Cancer Family Registry

Jenny N Poynter, Elizabeth T Jacobs, Jane C Figueiredo, Won H Lee, David V Conti, Peter T Campbell, A Joan Levine, Paul Limburg, Loic Le Marchand, Michelle Cotterchio, Polly A Newcomb, John D Potter, Mark A Jenkins, John L Hopper, David J Duggan, John A Baron, Robert W Haile

Journal article  |  2010  |  Cancer Epidemiology, Biomarkers & Prevention

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Population-based, Case-Control-Family Design to Investigate Genetic and Environmental Influences on Melanoma Risk Australian Melanoma Family Study

Anne E Cust, Helen Schmid, Judith A Maskiell, Jodie Jetann, Megan Ferguson, Elizabeth A Holland, Chantelle Agha-Hamilton, Mark A Jenkins, John Kelly, Richard F Kefford, Graham G Giles, Bruce K Armstrong, Joanne F Aitken, John L Hopper, Graham J Mann

Journal article  |  2009  |  American Journal of Epidemiology

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Penetrance of CDKN2A mutations estimated using population-based Australian families

Mark Jenkins, Anne Cust, Daniel Schmidt, Enes Makalic, Elizabeth Holland, Helen Scmid, Richard Kefford, Graham Giles, Armstrong Bruce, Joanne Aitkin, Graham Mann, John Hopper

Conference Proceedings  |  2009  |  GENETIC EPIDEMIOLOGY

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Analysis of families with Lynch syndrome complicated by advanced serrated neoplasia: the importance of pathology review and pedigree analysis

Michael D Walsh, Daniel D Buchanan, Rhiannon Walters, Aedan Roberts, Sven Arnold, Diane McKeone, Mark Clendenning, Andrew R Ruszkiewicz, Mark A Jenkins, John L Hopper, Jack Goldblatt, Jillian George, Graeme K Suthers, Kerry Phillips, Graeme P Young, Finlay Macrae, Musa Drini, Michael O Woods, Susan Parry, Jeremy R Jass, et al.

Journal article  |  2009  |  Familial Cancer

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Sociodemographic, Lifestyle, and Medical Risk Factors for Visual Impairment in an Urban Asian Population The Singapore Malay Eye Study

Elaine W Chong, Ecosse L Lamoureux, Mark A Jenkins, Tin Aung, Seang-Mei Saw, Tien Y Wong

Journal article  |  2009  |  Archives of Ophthalmology

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A Minimum Encoding Approach to Analysing GWAS Data

Enes Makalic, Daniel F Schmidt, Mark Jenkins, John Hopper

Conference Proceedings  |  2009  |  GENETIC EPIDEMIOLOGY

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Adherence to asthma management guidelines by middle-aged adults with current asthma

RK Kandane-Rathnayake, MC Matheson, JA Simpson, MLK Tang, DP Johns, D Meszaros, R Wood-Baker, I Feather, S Morrison, MA Jenkins, GG Giles, J Hopper, MJ Abramson, SC Dharmage, EH Walters

Journal article  |  2009  |  Thorax

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Role of MSH6 and PMS2 in the DNA Mismatch Repair Process and Carcinogenesis

Mark A Jenkins

Journal article  |  2009  |  Surgical Oncology Clinics of North America

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Associations between Smoking, Alcohol Consumption, and Colorectal Cancer, Overall and by Tumor Microsatellite Instability Status

Jenny N Poynter, Robert W Haile, Kimberly D Siegmund, Peter T Campbell, Jane C Figueiredo, Paul Limburg, Joanne Young, Loic Le Marchand, John D Potter, Michelle Cotterchio, Graham Casey, John L Hopper, Mark A Jenkins, Stephen N Thibodeau, Polly A Newcomb, John A Baronlo

Journal article  |  2009  |  Cancer Epidemiology, Biomarkers & Prevention

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Is uptake of genetic testing for colorectal cancer influenced by knowledge of insurance implications?

Louise A Keogh, Christine M van Vliet, David M Studdert, Judith A Maskiell, Finlay A Macrae, D James St John, Clara L Gaff, Mary Anne Young, Melissa C Southey, Graham G Giles, Doreen A Rosenthal, John L Hopper, Mark A Jenkins

Journal article  |  2009  |  Medical Journal of Australia

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Eye injuries in rural Victoria, Australia

Simon Raymond, Ian Favilla, Anh Nguyen, Mark Jenkins, Greg Mason

Journal article  |  2009  |  Clinical and Experimental Ophthalmology

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Breast Cancer Risk Is Not Increased in Individuals with TWISTI Mutation Confirmed Saethre-Chotzen Syndrome: An Australian Multicenter Study

Paul A James, Bronwyn Culling, Glenda Mullan, Mark Jenkins, George Elalkis, Anne M Turners, David M Mowat, Meredith Wilson, Peter Anderson, Ravi Savarirayan, Simon T Cliffe, Melody Caramins, Michael F Buckley, Kathy Tucker, Tony Roscioli

Journal article  |  2009  |  Genes, Chromosomes & Cancer

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Contralateral risk-reducing mastectomy in BRCA1/2 mutation carriers and other high-risk women in the Kathleen Cuningham Foundation Consortium for Research into Familial Breast Cancer (kConFab)

BE Kiely, MA Jenkins, JM McKinley, ML Friedlander, PC Weideman, R Milne, S McLachlan, JL Hopper, K Phillips

Conference Proceedings  |  2009  |  JOURNAL OF CLINICAL ONCOLOGY

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The association of global gene expression in human colon tumors with germline variation at rs6983267 on 8q24 suggests that this SNP is an eQTL hotspot

Gordon Okimoto, Maarit Tiirikainen, Naveen Babbar, Jenny Poynter, Lenora Loo, Michael Loomis, John Hopper, Mark Jenkins, Steven Gallinger, Stephen Thibodeau, Robert Haile, Graham Casey, David Duggan, Loic Le Marchand

Journal article  |  2009  |  CANCER RESEARCH

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The association of global gene expression in human colon tumors with germline variation at rs6983267 on 8q24 suggests that this SNP is an eQTL hotspot

Gordon Okimoto, Maarit Tiirikainen, Naveen Babbar, Jenny Poynter, Lenora Loo, Michael Loomis, John Hopper, Mark Jenkins, Steven Gallinger, Stephen Thibodeau, Robert Haile, Graham Casey, David Duggan, Loic Le Marchand

Journal article  |  2009  |  CANCER RESEARCH

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Classifying MLH1 and MSH2 Variants Using Bioinformatic Prediction, Splicing Assays, Segregation, and Tumor Characteristics

Sven Arnold, Daniel D Buchanan, Melissa Barker, Lesley Jaskowski, Michael D Walsh, Genevieve Birney, Michael O Woods, John L Hopper, Mark A Jenkins, Melissa A Brown, Sean V Tavtigian, David E Goldgar, Joanne P Young, Amanda B Spurdle

Journal article  |  2009  |  Human Mutation

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Germline MutY Human Homologue Mutations and Colorectal Cancer: A Multisite Case-Control Study

Sean P Cleary, Michelle Cotterchio, Mark A Jenkins, Hyeja Kim, Robert Bristow, Roger Green, Robert Haile, John L Hopper, Loic LeMarchand, Noralane Lindor, Patrick Parfrey, John Potter, Ban Younghusband, Steven Gallinger

Journal article  |  2009  |  Gastroenterology

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Relevance of the hygiene hypothesis to early vs. late onset allergic rhinitis

MC Matheson, EH Walters, JA Simpson, CL Wharton, A-L Ponsonby, DP Johns, MA Jenkins, GG Giles, JL Hopper, MJ Abramson, SC Dharmage

Journal article  |  2009  |  Clinical and Experimental Allergy

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Predictors of the use of complementary and alternative medicine (CAM) by women at high risk for breast cancer

KM Field, MA Jenkins, ML Friedlander, JM McKinley, MA Price, P Weideman, LA Keogh, SA McLachlan, GJ Lindeman, JL Hopper, PN Butow, KA Phillips

Journal article  |  2009  |  European Journal of Cancer

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Molecular screening of all colorectal tumors diagnosed before age 50 years followed by genetic testing efficiently identifies Lynch syndrome cases

Mark A Jenkins, James G Dowry, John L Hopper, Melissa C Southey

Journal article  |  2009  |  International Journal of Cancer

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The Association of Tumor Microsatellite Instability Phenotype with Family History of Colorectal Cancer

Bharati Bapat, Noralane M Lindor, John Baron, Kim Siegmund, Lin Li, Yingye Zheng, Robert Haile, Steve Gallinger, Jeremy R Jass, Joanne P Young, Michelle Cotterchio, Mark Jenkins, John Grove, Graham Casey, Stephen N Thibodeau, D Timothy Bishop, John L Hopper, Dennis Ahnen, Polly A Newcomb, Loic Le Marchand, et al.

Journal article  |  2009  |  Cancer Epidemiology, Biomarkers & Prevention

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The RAD51D E233G variant and breast cancer risk: population-based and clinic-based family studies of Australian women

James G Dowty, Felicity Lose, Mark A Jenkins, Jiun-Horng Chang, XiaoQing Chen, Jonathan Beesley, Gillian S Dite, Melissa C Southey, Graham B Byrnes, Andrea Tesoriero, Graham G Giles, John L Hopper, Amanda B Spurdle

Journal article  |  2008  |  Breast Cancer Research and Treatment

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Molecular Characterization of MSI-H Colorectal Cancer by MLH1 Promoter Methylation, Immunohistochemistry, and Mismatch Repair Germline Mutation Screening

Jenny N Poynter, Kimberly D Siegmund, Daniel J Weisenberger, Tiffany I Long, Stephen N Thibodeau, Noralane Lindor, Joanne Young, Mark A Jenkins, John L Hopper, John A Baron, Dan Buchanan, Graham Casey, A Joan Levine, Loic Le Marchand, Steven Gallinger, Bharati Bapat, John D Potter, Polly A Newcomb, Robert W Haile, Peter W Laird

Journal article  |  2008  |  Cancer Epidemiology, Biomarkers & Prevention

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The clinical phenotype of Lynch syndrome due to germ-line PMS2 mutations

Leigha Senter, Mark Clendenning, Kaisa Sotamaa, Heather Hampel, Jane Green, John D Potter, Annika Lindblom, Kristina Lagerstedt, Stephen N Thibodeau, Noralane M Lindor, Joanne Young, Ingrid Winship, James G Dowty, Darren M White, John L Hopper, Laura Baglietto, Mark A Jenkins, Albert de la Chaple

Journal article  |  2008  |  Gastroenterology

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Ethnicity and risk for colorectal cancers showing somatic BRAF V600E mutation or CpG island methylator phenotype

Dallas R English, Joanne P Young, Julie A Simpson, Mark A Jenkins, Melissa C Southey, Michael D Walsh, Daniel D Buchanan, Melissa A Barker, Andrew M Haydon, Simon G Royce, Aedan Roberts, Susan Parry, John L Hopper, Jeremy J Jass, Graham G Giles

Journal article  |  2008  |  Cancer Epidemiology, Biomarkers & Prevention

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Identifying the early-onset cases of breast and colorectal cancers most likely to carry a germline mutation in a "high-risk" cancer predisposition gene

M Southey, M Jenkins, S Ramus, J Dowty, G Dite, G Byrnes, G Giles, M McCredie, J Hopper

Conference Proceedings  |  2008  |  European Journal of Cancer Supplements

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Risk of cancer in MSH6 mutation carriers: an international collaboration

MA Jenkins, L Baglietto, JG Dowty, HF Vasen, A de la Chapelle, HL Hampel, MG Dunlop, SN Thibodeau, NM Lindor

Conference Proceedings  |  2008  |  Journal of Clinical Oncology

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Risk of cancer in MSH6 mutation carriers: an international collaboration.

MA Jenkins, L Baglietto, JG Dowty, HF Vasen, A de la Chapelle, HL Hampel, MG Dunlop, SN Thibodeau, NM Lindor, undefined Colon Cancer Family Registry

Journal article  |  2008  |  J Clin Oncol

11006 Background: Inherited mutations in mismatch repair genes increase risk of cancer. The majority of studies have concentrated ..

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Progesterone receptor polymorphisms and risk of breast cancer: results from two Australian breast cancer studies

Sharon E Johnatty, Amanda B Spurdle, Jonathan Beesley, Xiaoqing Chen, John L Hopper, David L Duffy, Georgia Chenevix-Trench

Journal article  |  2008  |  Breast Cancer Research and Treatment

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Is BRCA2 c.9079 G > A a predisposing variant for early onset breast cancer?

Fleur Hammet, Jessica George, Andrea A Tesoriero, Mark A Jenkins, Christopher Schroen, Letitia Smith, Anke Grabosch-Meehan, Gillian Dite, Margaret RE McCredie, Graham G Giles, Sean V Tavtigian, John L Hopper, Melissa C Southey

Journal article  |  2008  |  Breast Cancer Research and Treatment

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Smoking and risk of breast cancer in carriers of mutations in BRCA1 or BRCA2 aged less than 50 years

Journal article  |  2008  |  Breast Cancer Research and Treatment

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Association of a common AKAP9 variant with breast cancer risk: A collaborative analysis

Bernd Frank, Miriam Wiestler, Silke Kropp, Kari Hemminki, Amanda B Spurdle, Christian Sutter, Barbara Wappenschmidt, Xiaoqing Chen, Jonathan Beesley, John L Hopper, Alfons Meindl, Marion Kiechle, Tracy Slanger, Peter Bugert, Rita K Schmutzler, Claus R Bartram, Dieter Flesch-Janys, Elke Mutschelknauss, Katie Ashton, Ramona Salazar, et al.

Journal article  |  2008  |  Journal of the National Cancer Institute

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Cancer risk management practices of noncarriers within BRCA1/2 mutation - Positive families in the Kathleen Cuningham Foundation Consortium for Research into Familial Breast cancer

Sarah-Jane Dawson, Melanie A Price, Mark A Jenkins, Joanne M McKinley, Phyllis N Butow, Sue-Anne McLachlan, Geoffrey J Lindeman, Prue Weideman, Michael L Friedlander, John L Hopper, Kelly-Anne Phillips

Journal article  |  2008  |  Journal of Clinical Oncology

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Variants on 9p24 and 8q24 are associated with risk of colorectal cancer: Results from the colon cancer family registry

Jenny N Poynter, Jane C Figueiredo, David V Conti, Kathleen Kennedy, Steven Gallinger, Kimberly D Siegnumd, Graham Casey, Stephen N Thibodeau, Mark A Jenkins, John L Hopper, Graham B Byrnes, John A Baron, Ellen L Goode, Maarit Tiirikainen, Noralane Lindor, John Grove, Polly Newcomb, Jeremy Jass, Joanne Young, John D Potter, et al.

Journal article  |  2007  |  Cancer Research

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Association between single-nucleotide polymorphisms in hormone metabolism and DNA repair genes and epithelial ovarian cancer: Results from two Australian studies and an additional validation set

Jonathan Beesley, Susan J Jordan, Amanda B Spurdle, Honglin Song, Susan J Ramus, Suzanne Kruger Kjaer, Estrid Hogdall, Richard A DiCioccio, Valerie McGuire, Alice S Whittemore, Simon A Gayther, Paul DP Pharoah, Penelope M Webb, Georgia Chenevix-Trench

Journal article  |  2007  |  Cancer Epidemiology, Biomarkers & Prevention

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RAD51 135G -> C modifies breast cancer risk among BRCA2 mutation carriers: Results from a combined analysis of 19 studies

Antonis C Antoniou, Olga M Sinilnikova, Jacques Simard, Melanie Leone, Martine Dumont, Susan L Neuhausen, Jeffery P Struewing, Dominique Stoppa-Lyonnet, Laure Barjhoux, David J Hughes, Isabelle Coupier, Muriel Belotti, Christine Lasset, Timothy R Rebbeck, Theresa Wagner, Henry T Lynch, Susan M Domchek, Katherine L Nathanson, Judy E Garber, Jeffrey Weitzel, et al.

Journal article  |  2007  |  American Journal of Human Genetics

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Breast-feeding and atopic disease: A cohort study from childhood to middle age

Melanie Claire Matheson, Bircan Erbas, Aindralal Balasuriya, Mark Andrew Jenkins, Cathryn Leisa Wharton, Mimi Lai-Kuan Tang, Michael John Abramson, Eugene Haydn Walters, John Llewelyn Hopper, Shyamali Chandrika Dharmage

Journal article  |  2007  |  Journal of Allergy and Clinical Immunology

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Childhood allergic rhinitis predicts asthma incidence and persistence to middle age: A longitudinal study

John A Burgess, E Haydn Walters, Graham B Byrnes, Melanie C Matheson, Mark A Jenkins, Cathryn L Wharton, David P Johns, Michael J Abramson, John L Hopper, Shyamali C Dharmage

Journal article  |  2007  |  Journal of Allergy and Clinical Immunology

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Serrated pathway colorectal cancer in the population: Genetic consideration

Joanne Young, Mark Jenkins, Susan Parry, Bruce Young, Derek Nancarrow, Dallas English, Graham Giles, Jeremy Jass

Journal article  |  2007  |  Gut

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Prostate screening uptake in Australian BRCA1 and BRCA2 carriers

Joanne M McKinley, Prue C Weideman, Mark A Jenkins, Michael L Friedlander, John L Hopper, Sue-Anne McLachlan, Geoffrey J Lindeman, Kelly-Anne Phillips

Journal article  |  2007  |  Hereditary Cancer in Clinical Practice

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Prophylactic oophorectomy for the prevention of breast and ovarian cancer in high risk mutation carriers: meta-analysis

GL Chew, M Jenkins, KA Phillips

Conference Proceedings  |  2007  |  European Journal of Cancer Supplements

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Accuracy of colorectal polyp self-reports: Findings from the colon cancer family registry

Lisa Madlensky, Darshana Daftary, Terrilea Burnett, Patricia Harmon, Mark Jenkins, Judi Maskiell, Sandra Nigon, Kerry Phillips, Allyson Templeton, Paul J Limburg, Robert W Haile, John D Potter, Steven Gallinger, John A Baron

Journal article  |  2007  |  Cancer Epidemiology, Biomarkers & Prevention

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A range of simple summary genome-wide statistics for detecting genetic linkage using high density marker data

Ian W Saunders, Garry N Hannan, Jesper Brohede, Graham G Giles, Mark A Jenkins, John L Hopper, Melissa C Southeys

Journal article  |  2007  |  Genetic Epidemiology

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Validation study of the LAMBDA model for predicting the BRCA1 or BRCA2 mutation carrier status of North American Ashkenazi Jewish women

C Apicella, JG Dowty, GS Dite, MA Jenkins, RT Senle, MB Daly, IL Andrulis, EM John, SS Buys, FP Li, G Glendon, W Chung, H Ozcelik, A Miron, K Kotar, MC Southey, WD Foulkes, JL Hopper

Journal article  |  2007  |  Clinical Genetics

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Pathology features in Bethesda guidelines predict colorectal cancer microsatellite instability: A population-based study

Mark A Jenkins, Shinichi Hayashi, Anne-Marie O'Shea, Lawrence J Burgart, Tom C Smyrk, David Shimizu, Paul M Waring, Andrew R Ruszkiewicz, Aaron F Pollett, Mark Redston, Melissa A Barker, John A Baron, Graham R Casey, James G Dowty, Graham G Giles, Paul Limburg, Polly Newcomb, Joanne P Young, Michael D Walsh, Stephen N Thibodeau, et al.

Journal article  |  2007  |  Gastroenterology

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Genome-wide association study identifies novel breast cancer susceptibility loci

Douglas F Easton, Karen A Pooley, Alison M Dunning, Paul DP Pharoah, Deborah Thompson, Dennis G Ballinger, Jeffery P Struewing, Jonathan Morrison, Helen Field, Robert Luben, Nicholas Wareham, Shahana Ahmed, Catherine S Healey, Richard Bowman, Kerstin B Meyer, Christopher A Haiman, Laurence K Kolonel, Brian E Henderson, Loic Le Marchand, Paul Brennan, et al.

Journal article  |  2007  |  Nature

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Microsatellite instability markers for identifying early-onset colorectal cancers caused by germ-line mutations in DNA mismatch repair genes

Leeanne J Mead, Mark A Jenkins, Joanne Young, Simon G Royce, Letitia Smith, D James B St John, Finlay Macrae, Graham G Giles, John L Hopper, Melissa C Southey

Journal article  |  2007  |  Clinical Cancer Research

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Rationale for, and approach to, studying modifiers of risk in persons with a genetic predisposition to colorectal cancer.

Mark A Jenkins, Melissa C Southey, Graham G Giles, John L Hopper

Journal article  |  2007  |  Current Oncology Reports

We address the issue of modifiers of risk for persons who are, on average, at high risk of colorectal cancer due to carrying germl..

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Childhood adiposity predicts adult-onset current asthma in females: a 25-yr prospective study

JA Burgess, EH Walters, GB Byrnes, GG Giles, MA Jenkins, MJ Abramson, JL Hopper, SC Dharmage

Journal article  |  2007  |  European Respiratory Journal

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Is childhood immunisation associated with atopic disease from age 7 to 32 years?

Kazunori Nakajima, Shyamali C Dharmage, John B Carlin, Cathryn L Wharton, Mark A Jenkins, Graham G Giles, Michael J Abramson, E Haydn Walters, John L Hopper

Journal article  |  2007  |  Thorax

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Stability of BAT26 in Lynch syndrome colorectal tumours

Lesley Jaskowski, Joanne Young, Leigh Jackson, Sven Arnold, Melissa A Barker, Michael D Walsh, Daniel D Buchanan, Samantha Holman, Kara A Mensink, Mark A Jenkins, John L Hopper, Stephen N Thibodeau, Jeremy R Jass, Amanda B Spurdle

Journal article  |  2007  |  European Journal of Human Genetics

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Characterization of the breast cancer associated ATM 7271T > G (V2424G) mutation by gene expression profiling

Nic Waddell, Jyoti Jonnalagadda, Anna Marsh, Scott Grist, Mark Jenkins, Karen Hobson, Malcolm Taylor, Geoff J Lindeman, Sean V Tavtigian, Graeme Suthers, David Goldgar, Peter J Oefner, Darrin Taylor, Sean Grimmond, Kum Kum Khanna, Georgia Chenevix-Trench

Journal article  |  2006  |  Genes, Chromosomes & Cancer

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Rationale for, and approach to, studying modifiers of risk in persons with a genetic predisposition to colorectal cancer

MA Jenkins, MC Southey, GG Giles, JL Hopper

Journal article  |  2006  |  Current Colorectal cancer Reports

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Lessons learnt so far from the current follow up of the Tasmanian Asthma Survey: A longitudinal study of respiratory health from age 7 to 44 years

EH Walters, MC Matheson, J Burgess, C Wharton, M Jenkins, D Johns, MJ Abramson, JL Hopper, SC Dharmage

Conference Proceedings  |  2006  |  THORAX

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Who remembers whether they had asthma as children?

John A Burgess, E Haydn Walters, Graham B Byrnes, Cathryn Wharton, Mark A Jenkins, Michael J Abramson, John L Hopper, Shyamali C Dharmage

Journal article  |  2006  |  Journal of Asthma (New York)

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Histopathological features of breast cancer in carriers of ATM gene variants

RL Balleine, R Murali, AM Bilous, G Farshid, P Waring, P Provan, K Byth, H Thorne, JA Kirk

Journal article  |  2006  |  Histopathology

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Population-based estimates of breast cancer risks associated with ATM gene variants c.7271T > G and c.1066-6T > G (IVS10-6T > G) from the breast cancer family registry

JL Bernstein, S Teraoka, MC Southey, MA Jenkins, IL Andrulis, JA Knight, EM John, R Lapinski, AL Wolitzer, AS Whittemore, D West, D Seminara, ER Olson, AB Spurdle, G Chenevix-Trench, GG Giles, JL Hopper, P Concannon

Journal article  |  2006  |  Human Mutation

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Morphology of breast cancer as a means of triage of patients for BRCA1 genetic testing

Gelareh Farshid, Rosemary L Balleine, Margaret Cummings, Paul Waring

Journal article  |  2006  |  American Journal of Surgical Pathology

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Evaluation of models to predict BRCA germline mutations

HH Kang, R Williams, J Leary, C Ringland, J Kirk, R Ward

Journal article  |  2006  |  British Journal of Cancer

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BRCA1 and BRCA2 mutation carriers, oral contraceptive use, and breast cancer before age 50

Robert W Haile, Duncan C Thomas, Valerie McGuire, Anna Felberg, Esther M John, Roger L Milne, John L Hopper, Mark A Jenkins, A Joan Levine, Mary M Daly, Saundra S Buys, Ruby T Senie, Irene L Andrulis, Julia A Knight, Andrew K Godwin, Melissa Southey, Margaret RE McCredie, Graham G Giles, Lesley Andrews, Katherine Tucker, et al.

Journal article  |  2006  |  Cancer Epidemiology, Biomarkers & Prevention

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Large genomic alterations in hMSH2 and hMLH1 in early-onset colorectal cancer: identification of a large complex de novo hMLH1 alteration

L Smith, A Tesoriero, L Mead, S Royce, G Grubb, J Young, G Giles, M Jenkins, F Macrae, JL Hopper, MC Southey

Journal article  |  2006  |  Clinical Genetics

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Risk-reducing surgery, screening and chemoprevention practices of BRCA1 and BRCA2 mutation carriers: a prospective cohort study

K-A Phillips, MA Jenkins, GJ Lindeman, SA McLachlan, JM McKinley, PC Weideman, JL Hopper, ML Friedlander

Journal article  |  2006  |  Clinical Genetics

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No increased risk of breast cancer associated with alcohol consumption among carriers of BRCA1 and BRCA2 mutations ages < 50 years

Valerie McGuire, Esther M John, Anna Felberg, Robert W Haile, Norman F Boyd, Duncan C Thomas, Mark A Jenkins, Roger L Milne, Mary B Daly, John Ward, Mary Beth Terry, Irene L Andrulis, Julia A Knight, Andrew K Godwin, Graham G Giles, Melissa Southey, Dee W West, John L Hopper, Alice S Whittemore

Journal article  |  2006  |  Cancer Epidemiology, Biomarkers & Prevention

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Low somatic K-ras mutation frequency in colorectal cancer diagnosed under the age of 45 years

Kathryn Alsop, Leeanne Mead, Letitia D Smith, Simon G Royce, Andrea A Tesoriero, Joanne P Young, Andrew Haydon, Garry Grubb, Graham G Giles, Mark A Jenkins, John L Hopper, Melissa C Southey

Journal article  |  2006  |  European Journal of Cancer

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Cancer risk management practices of non-carriers within BRCA1/2 mutation positive families in the Kathleen Cunningham Consortium for Research into Familial Breast Cancer (kConFab).

S Dawson, J McKinley, M Jenkins, S McLachlan, G Lindeman, M Friedlander, J Hopper, K Phillips

Conference Proceedings  |  2006  |  JOURNAL OF CLINICAL ONCOLOGY

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Parity and decreased use of oral contraceptives as predictors of asthma in young women

MA Jenkins, SC Dharmage, LB Flander, JA Douglass, AM Ugoni, JB Carlin, SM Sawyer, GG Giles, JL Hopper

Journal article  |  2006  |  Clinical and Experimental Allergy

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In Reply:

Melissa C Southey, Mark A Jenkins, John L Hopper, Finlay A Macrae, Graham G Giles

Journal article  |  2006  |  Journal of Clinical Oncology

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Is it time to abandon microsatellite instability as a pre-screen for selecting families for mutation testing for mismatch repair genes? Reply

MC Southey, MA Jenkins, JL Hopper, FA Macrae, GG Giles

Journal article  |  2006  |  Journal of Clinical Oncology

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Tracing 8,600 participants 36 years after recruitment at age seven for the Tasmanian Asthma Study

Cathryn Wharton, Shyamali Dharmage, Mark Jenkins, Gillian Dite, John Hopper, Graham Giles, Michael Abramson, E Haydn Walters

Journal article  |  2006  |  Australian and New Zealand Journal of Public Health

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Chromosome 2q24.2 is lost in sporadic but not in BRCA1-associated ovarian carcinomas

M Aghmesheh, ZH Suo, M Friedlander, JM Nesland, J Kaern, M Stewart, A Dorum, KM Tucker, MF Buckley

Journal article  |  2006  |  Pathology

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Cancer risks for mismatch repair gene mutation carriers: A population-based early onset case-family study

MA Jenkins, L Baglietto, JG Dowty, CM Van Vliet, L Smith, LJ Mead, FA Macrae, DJB St John, JR Jass, GG Giles, JL Hopper, MC Southey

Journal article  |  2006  |  Clinical Gastroenterology and Hepatology

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Genetic and histopathologic evaluation of BRCA1 and BRCA2 DNA sequence variants of unknown clinical significance

G Chenevix-Trench, S Healey, S Lakhani, P Waring, M Cummings, R Brinkworth, AM Deffenbaugh, LA Burbidge, D Pruss, T Judkins, T Scholl, A Bekessy, A Marsh, P Lovelock, M Wong, A Tesoriero, H Renard, M Southey, JL Hopper, K Yannoukakos, et al.

Journal article  |  2006  |  Cancer Research

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Risk of colorectal cancer in monoallelic and biallelic carriers of MYH mutations: A population-based case-family study

MA Jenkins, ME Croitoru, N Monga, SP Cleary, M Cotterchio, JL Hopper, S Gallinger

Journal article  |  2006  |  Cancer Epidemiology, Biomarkers & Prevention

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Measures of familial aggregation depend on definition of family history: meta-analysis for colorectal cancer

L Baglietto, MA Jenkins, G Severi, GG Giles, DT Bishop, P Boyle, JL Hopper

Journal article  |  2006  |  Journal of Clinical Epidemiology

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Genetic, functional, and histopathological evaluation of two C-terminal BRCA1 missense variants

PK Lovelock, S Healey, W Au, EYM Sum, A Tesoriero, EM Wong, S Hinson, R Brinkworth, A Bekessy, O Diez, L Izatt, E Solomon, M Jenkins, H Renard, J Hopper, P Waring, SV Tavtigian, D Goldgar, GJ Lindeman, JE Visvader, et al.

Journal article  |  2006  |  Journal of Medical Genetics

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The Colorectal Cancer Family Registry: An international resource for studying the genetic and molecular epidemiology of colorectal cancer

M JENKINS, F MACRAE, undefined Young, undefined Barker, undefined Leggett, undefined Goldblatt, undefined Kirk, undefined Tucker, undefined Suthers, undefined Young, undefined Parry, undefined Arnold, I WINSHIP, J MASKIELL, undefined Giles, undefined Jass, J HOPPER

Journal article  |  2006  |  Gastrointestinal Cancer Update

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Analysis of cancer risk and BRCA1 and BRCA2 mutation prevalence in the kConFab familial breast cancer resource

GJ Mann, H Thorne, RL Balleine, PN Butow, CL Clarke, E Edkins, GM Evans, S Fereday, E Haan, M Gattas, GG Giles, J Goldblatt, JL Hopper, J Kirk, JA Leary, G Lindeman, E Niedermayr, KA Phillips, S Picken, GM Pupo, et al.

Journal article  |  2006  |  Breast Cancer Research

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Childhood obesity predicts current incident asthma in adult women

JA Burgess, EH Walters, GB Byrnes, MA Jenkins, GG Giles, MJ Abramson, JL Hopper, SC Dharmage

Conference Proceedings  |  2005  |  THORAX

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Molecular characterization and cancer risk associated with BRCA1 and BRCA2 splice site variants identified in multiple-case breast cancer families.

AA Tesoriero, EM Wong, MA Jenkins, JL Hopper, MA Brown, G Chenevix-Trench, AB Spurdle, MC Southey, undefined kConFab

Journal article  |  2005  |  Human Mutation

Genetic screening of women from multiple-case breast cancer families and other research-based endeavors have identified an extensi..

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Consent and population-based family cancer genetic research: Ethical and methodological issues

CM van Vliet, MA Jenkins, DM Gertig, JL Hopper

Conference Proceedings  |  2005  |  GENETIC EPIDEMIOLOGY

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A protein-truncating mutation in CYP17A1 in three sisters with early-onset breast cancer

JL Hopper, VM Hayes, AB Spurdle, G Chenevix-Trench, MA Jenkins, RL Milne, GS Dite, AA Tesoriero, MRE McCredie, GG Giles, MC Southey

Journal article  |  2005  |  Human Mutation

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Use of molecular tumor characteristics to prioritize mismatch repair gene testing in early-onset colorectal cancer

MC Southey, MA Jenkins, L Mead, J Whitty, M Trivett, AA Tesoriero, LD Smith, K Jennings, G Grubb, SG Royce, MD Walsh, MA Barker, JP Young, JR Jass, DJB St John, FA Macrae, GG Giles, JL Hopper

Journal article  |  2005  |  Journal of Clinical Oncology

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Isolated loss of PMS2 expression in colorectal cancers: Frequency, patient age, and familial aggregation

S Gill, NM Lindor, LJ Burgart, R Smalley, O Leontovich, AJ French, RM Goldberg, DJ Sargent, JR Jass, JL Hopper, MA Jenkins, J Young, MA Barker, MD Walsh, AR Ruszkiewicz, SN Thibodeau

Journal article  |  2005  |  Clinical Cancer Research

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Two ATM variants and breast cancer risk.

Deborah Thompson, Antonis C Antoniou, Mark Jenkins, Anna Marsh, Xiaoqing Chen, Tierney Wayne, Andrea Tesoriero, Roger Milne, Amanda Spurdle, Yvonne Thorstenson, Melissa Southey, Graham G Giles, Kum Kum Khanna, Joseph Sambrook, Peter Oefner, David Goldgar, John L Hopper, Doug Easton, Georgia Chenevix-Trench, undefined KConFab Investigators

Journal article  |  2005  |  Human mutation

The ATM gene is mutated in ataxia-telangiectasia (AT). Heterozygote female relatives of AT cases have a 2-7fold increased risk of ..

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Evidence for BRAF mutation and variable levels of microsatellite instability in a syndrome of familial colorectal cancer

J Young, MA Barker, LA Simms, MD Walsh, KG Biden, D Buchanan, R Buttenshaw, VLJ Whitehall, S Arnold, L Jackson, T Kambara, KJ Spring, MA Jenkins, GJ Walker, JL Hopper, BA Leggett, JR Jass

Journal article  |  2005  |  Clinical Gastroenterology and Hepatology

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CYP17 genetic polymorphism, breast cancer, and breast cancer risk factors: Australian Breast Cancer Family Study

JH Chang, DM Gertig, XQ Chen, GS Dite, MA Jenkins, RL Milne, MC Southey, MRE McCredie, GG Giles, G Chenevix-Trench, JL Hopper, AB Spurdle

Journal article  |  2005  |  Breast Cancer Research

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Prognosis of premenopausal breast cancer and childbirth prior to diagnosis

KA Phillips, RL Milne, ML Friedlander, MA Jenkins, MRE McCredie, GG Giles, JL Hopper

Journal article  |  2004  |  Journal of Clinical Oncology

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Genetic, histopathological and functional analysis of unclassified variants of BRCA1 and BRCA2.

G Chenevix-Trench, A Spurdle, M Brown, P Lovelock, A Tesoriero, M Southey, M Jenkins, P Waring, D Goldgar, S Tavtigian, F Couch, B Henderson, J Visvader, J Hopper

Conference Proceedings  |  2004  |  BREAST CANCER RESEARCH AND TREATMENT

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Risk of female breast cancer and the BRCA2 N372H polymorphism: a population-based case family study.

MA Jenkins, RL Milne, MC Southey, AB Spurdie, G Chenevix-Trench, JL Hopper

Conference Proceedings  |  2003  |  AMERICAN JOURNAL OF HUMAN GENETICS

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What causes early onset breast cancer in a population-based sample of Australian women with a strong family history?

MC Southey, AA Tesoriero, SG Royce, L Smith, P MacAulay, J Cui, MA Jenkins, GS Dite, RL Milne, G Chenevix-Trench, A Spurdle, GG Giles, MRE McCredie, DJ Venter, JL Hopper

Conference Proceedings  |  2003  |  AMERICAN JOURNAL OF HUMAN GENETICS

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Mutation and segregation analysis of ATM alleles in 192 Australian breast cancer families.

T Wayne, G Chenevix-Trench, M Jenkins, T Bachrich, D Muhr, R Davis, N Albert, P Oefner, Y Thorstenson

Conference Proceedings  |  2003  |  AMERICAN JOURNAL OF HUMAN GENETICS

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SMAD4 tumor suppressor in early onset colorectal cancers

SG Royce, KJ Alsop, AM Haydon, MA Jenkins, LJ Mead, GG Giles, JL Hopper, MC Southey

Conference Proceedings  |  2003  |  AMERICAN JOURNAL OF HUMAN GENETICS

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A specific GFP expression assay, penetrance estimate, and histological assessment for a putative splice site mutation in BRCA1

MC Southey, A Tesoriero, MA Young, AJ Holloway, MA Jenkins, J Whitty, S Misfud, SA McLachlan, DJ Venter, JE Armes

Journal article  |  2003  |  Human Mutation

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Contributions of ATM mutations to familial breast and ovarian cancer

YR Thorstenson, A Roxas, R Kroiss, MA Jenkins, KM Yu, T Bachrich, D Muhr, TL Wayne, G Chu, RW Davis, TMU Wagner, PJ Oefner

Journal article  |  2003  |  Cancer Research

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Average age-specific cumulative risk of breast cancer according to type and site of germline mutations in BRCA1 and BRCA2 estimated from multiple-case breast cancer families attending Australian family cancer clinics

CL Scott, MA Jenkins, MC Southey, TA Davis, JA Leary, DF Easton, KA Phillips, JL Hopper

Journal article  |  2003  |  Human Genetics

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Familial risks, early-onset breast cancer, and BRCA1 and BRCA2 germline mutations

GS Dite, MA Jenkins, MC Southey, JS Hocking, GG Giles, MRE McCredie, DJ Venter, JL Hopper

Journal article  |  2003  |  Journal of the National Cancer Institute

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After hMSH2 and hMLH1-what next? Analysis of three-generational, population-based, early-onset colorectal cancer families

MA Jenkins, L Baglietto, GS Dite, DJ Jolley, MC Southey, J Whitty, LJ Mead, DJBS John, FA Macrae, DT Bishop, DJ Venter, GG Giles, JL Hopper

Journal article  |  2002  |  International Journal of Cancer

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Assessing breast cancer risk in BRCA1 and BRCA2 mutation-carriers by parity: An application of two analytical methods to clinic-based and population-based family data.

R Milne, M Jenkins, C Scott, KA Phillips, M Southey, A Tesoriero, D Venter, G Dite, M McCredie, G Giles, J Hopper

Conference Proceedings  |  2002  |  CANCER EPIDEMIOLOGY BIOMARKERS & PREVENTION

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Strong familial risks associated with early-onset breast cancer are only partly BRCA1- or BRCA2-related.

GS Dite, MA Jenkins, JS Hocking, GG Giles, MRE McCredie, MC Southey, DJ Venter, JL Hopper

Conference Proceedings  |  2002  |  CANCER EPIDEMIOLOGY BIOMARKERS & PREVENTION

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A meta-analysis of effectiveness of influenza vaccine in persons aged 65 years and over living in the community

T Vu, S Farish, M Jenkins, H Kelly

Journal article  |  2002  |  Vaccine

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Dominant negative ATM mutations in breast cancer families

G Chenevix-Trench, AB Spurdle, M Gatei, H Kelly, A Marsh, XQ Chen, K Donn, M Cummings, D Nyholt, MA Jenkins, C Scott, GM Pupo, T Dork, R Bendix, J Kirk, K Tucker, MRE McCredie, JL Hopper, J Sambrook, GJ Mann, et al.

Journal article  |  2002  |  Journal of the National Cancer Institute

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Evidence for genetic associations between asthma, atopy, and bronchial hyperresponsiveness - A study of 8-to 18-yr-old twins

JR Clarke, MA Jenkins, JL Hopper, JB Carlin, C Mayne, DG Clayton, MF Dalton, DP Holst, CF Robertson

Journal article  |  2000  |  American Journal of Respiratory and Critical Care Medicine

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General practitioners: Their contact with maternal and child health nurses in postnatal care

C Mbwili-Muleya, J Gunn, M Jenkins

Journal article  |  2000  |  Journal of Paediatrics and Child Health

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Modeling the probability that Ashkenazi Jewish women carry a founder mutation in BRCA1 or BRCA2

JL Hopper, MA Jenkins

Journal article  |  1999  |  The American Journal of Human Genetics

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BRCA1 mutations and other sequence variants in a population based sample of Australian women with breast cancer

MC Southey, AA Tesoriero, CR Andersen, KM Jennings, SM Brown, GS Dite, MA Jenkins, RH Osborne, JA Maskiell, L Porter, GG Giles, MRE McCredie, JL Hopper, DJ Venter

Journal article  |  1999  |  British Journal of Cancer

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Design and analysis issues in a population-based, case-control-family study of the genetic epidemiology of breast cancer and the Co-operative Family Registry for Breast Cancer Studies (CFRBCS).

JL Hopper, G Chenevix-Trench, DJ Jolley, GS Dite, MA Jenkins, DJ Venter, MR McCredie, GG Giles

Journal article  |  1999  |  JNCI Monographs

BACKGROUND: Historically, studies of the "genetic epidemiology" of cancer have used nonsystematically sampled kindreds with numero..

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Regressive logistic modeling of familial aggregation for asthma in 7,394 population-based nuclear families

MA Jenkins, JL Hopper, GG Giles

Journal article  |  1997  |  Genetic Epidemiology

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Validation of questionnaire and bronchial hyperresponsiveness against respiratory physician assessment in the diagnosis of asthma

MA Jenkins, JR Clarke, JB Carlin, CF Robertson, JL Hopper, MF Dalton, DP Holst, K Choi, GG Giles

Journal article  |  1996  |  International Journal of Epidemiology

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INCREASE IN THE SELF-REPORTED PREVALENCE OF ASTHMA AND HAY-FEVER IN ADULTS OVER THE LAST GENERATION - A MATCHED PARENT-OFFSPRING STUDY

JL HOPPER, MA JENKINS, JB CARLIN, GG GILES

Journal article  |  1995  |  Australian Journal of Public Health

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FACTORS IN CHILDHOOD AS PREDICTORS OF ASTHMA IN ADULT LIFE

MA JENKINS, JL HOPPER, G BOWES, JB CARLIN, LB FLANDER, GG GILES

Journal article  |  1994  |  BMJ

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ASTHMA, ALLERGY AND ATOPY IN SOUTHERN CHINESE SCHOOL STUDENTS

R LEUNG, M JENKINS

Journal article  |  1994  |  Clinical <html_ent glyph="@amp;" ascii="&amp;"/> Experimental Allergy

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The associations between childhood asthma and atopy, and parental asthma, hay fever and smoking.

MA Jenkins, JL Hopper, LB Flander, JB Carlin, GG Giles

Journal article  |  1993  |  Paediatric and Perinatal Epidemiology

The aim of this analysis was to examine the degree to which a life time prevalence of asthma in a 7-year-old child is statisticall..

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ACCURACY OF ASTHMA DEATH STATISTICS IN AUSTRALIA

MA JENKINS, AR RUBINFELD, CF ROBERTSON, G BOWES

Journal article  |  1992  |  Australian Journal of Public Health

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Use of antiasthmatic drugs in Australia.

Journal article  |  1991  |  Medical Journal of Australia

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USE OF ANTIASTHMATIC DRUGS IN AUSTRALIA

MA JENKINS, SF HURLEY, G BOWES, JJ MCNEIL

Journal article  |  1990  |  Medical Journal of Australia

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TRENDS IN AUSTRALIAN MORTALITY OF ASTHMA, 1979-1985

MA JENKINS, SF HURLEY, DJ JOLLEY, RG OLIVER, AJ MCLEAN, JJ MCNEIL

Journal article  |  1988  |  Medical Journal of Australia

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Scholarly Works

Keyword Analysis

Clinical Health (organs, Diseases and Abnormal Conditions)
Oncology and Carcinogenesis
Public Health and Health Services
Clinical Sciences
Specific Population Health (excl. Indigenous Health)
Clinical (organs, Diseases and Abnormal Conditions)
Genetics
Public Health (excl. Specific Population Health)
Public Health
Immunology

News

Displaying the 2 most recent news articles by Mark Jenkins.

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We don't know menopausal hormone therapy causes breast cancer, but the evidence continues to suggest a link

Martha Hickey, Mark Jenkins

September 3, 2019
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A chip off the DNA block

John Hopper, Mark Jenkins

February 1, 2016

2

News Articles

Honours, Awards and Fellowships

1990

Victorian Health Promotion Student Scholarship (3 years)

VicHealth

1

Award

Credentials

Positions

Nhmrc Professorial Fellow

Melbourne School Of Population And Global Health

Member

University of Melbourne Cancer Research Centre

Editorial Board

Cancer Epidemiology, Biomarkers & Prevention

Member

International Society of Inherited Gastrointestinal Tumours

Director

University of Melbourne Centre for Epidemiology and Biostatistics

Education

Doctor of Philosophy

University of Melbourne

Bachelor of Science

Monash University

Links