Ashley Bush

Copper and lipid metabolism: A reciprocal relationship

Bryce Blades, Scott Ayton, Ya Hui Hung, Ashley Bush, Sharon La Fontaine

Journal article  |  2021  |  BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS

BACKGROUND: Copper and lipid metabolism are intimately linked, sharing a complex, inverse relationship in the periphery (outside o..

Characterization of Selenium Compounds for Anti-ferroptotic Activity in Neuronal Cells and After Cerebral Ischemia-Reperfusion Injury

Qing-Zhang Tuo, Shashank Masaldan, Adam Southon, Celeste Mawal, Scott Ayton, Ashley Bush, Peng Lei, Abdel Ali Belaidi

Journal article  |  2021  |  NEUROTHERAPEUTICS

The emergence of ferroptosis as a cell death pathway associated with brain disorders including stroke and neurodegenerative diseas..

Acute phase markers in CSF reveal inflammatory changes in Alzheimer's disease that intersect with pathology, APOE 64, sex and age (vol 198, 101904, 2021)

Scott Ayton, Shorena Janelidze, Blaine Roberts, Sebastian Palmqvist, Pawel Kalinowski, Ibrahima Diouf, Abdel A Belaidi, Erik Stomrud, Ashley I Bush, Oskar Hansson

Journal article  |  2021  |  PROGRESS IN NEUROBIOLOGY

The publisher regrets the following errors in the above mentioned article: In the original manuscript there were the following err..

An Online, Person-Centered, Risk Factor Management Program to Prevent Cognitive Decline: Protocol for A Prospective Behavior-Modification Blinded Endpoint Randomized Controlled Trial.

Yen Ying Lim, Darshini Ayton, Stephanie Perin, Alexandra Lavale, Nawaf Yassi, Rachel Buckley, Christopher Barton, Loren Bruns, Renata Morello, Stephanie Pirotta, Emily Rosenich, Shantha MW Rajaratnam, Richard Sinnott, Amy Brodtmann, Ashley I Bush, Paul Maruff, Leonid Churilov, Anna Barker, Matthew P Pase, undefined BetterBrains Research Group

Journal article  |  2021  |  J Alzheimers Dis

BACKGROUND: Several modifiable risk factors for dementia have been identified, although the extent to which their modification lea..

The acute phase protein lactoferrin is a key feature of Alzheimer's disease and predictor of A beta burden through induction of APP amyloidogenic processing

Andrew Tsatsanis, Andrew N McCorkindale, Bruce X Wong, Ellis Patrick, Tim M Ryan, Robert W Evans, Ashley I Bush, Greg T Sutherland, Asipu Sivaprasadarao, Boris Guennewig, James A Duce

Journal article  |  2021  |  MOLECULAR PSYCHIATRY

Amyloidogenic processing of the amyloid precursor protein (APP) forms the amyloid-β peptide (Aβ) component of pathognomonic extrac..

From mouse to mouse‐ear cress: Nanomaterials as vehicles in plant biotechnology

Xue Xia, Bingyang Shi, Lei Wang, Yang Liu, Yan Zou, Yun Zhou, Yu Chen, Meng Zheng, Yingfang Zhu, Jingjing Duan, Siyi Guo, Ho Won Jang, Yuchen Miao, Kelong Fan, Feng Bai, Wei Tao, Yong Zhao, Qingyu Yan, Gang Cheng, Huiyu Liu, et al.

Journal article  |  2021  |  Exploration

Regional brain iron associated with deterioration in Alzheimer's disease: A large cohort study and theoretical significance

Scott Ayton, Stuart Portbury, Pawel Kalinowski, Puja Agarwal, Ibrahima Diouf, Julie A Schneider, Martha Clare Morris, Ashley I Bush

Journal article  |  2021  |  ALZHEIMERS & DEMENTIA

OBJECTIVE: This paper is a proposal for an update of the iron hypothesis of Alzheimer's disease (AD), based on large-scale emergin..

An integrated mass spectrometry imaging and digital pathology workflow for objective detection of colorectal tumours by unique atomic signatures

Bence Paul, Kai Kysenius, James B Hilton, Michael WM Jones, Robert W Hutchinson, Daniel D Buchanan, Christophe Rosty, Fred Fryer, Ashley Bush, Janet M Hergt, Jon D Woodhead, David P Bishop, Philip A Doble, Michelle M Hill, Peter J Crouch, Dominic J Hare

Journal article  |  2021  |  CHEMICAL SCIENCE

Tumours are abnormal growths of cells that reproduce by redirecting essential nutrients and resources from surrounding tissue. Cha..

Development of Novel Therapeutics Targeting the Blood-Brain Barrier: From Barrier to Carrier

Jia Li, Meng Zheng, Olga Shimoni, William A Banks, Ashley I Bush, Jennifer R Gamble, Bingyang Shi

Journal article  |  2021  |  ADVANCED SCIENCE

The blood-brain barrier (BBB) is a highly specialized neurovascular unit, initially described as an intact barrier to prevent toxi..

Zinc drives vasorelaxation by acting in sensory nerves, endothelium and smooth muscle

Ashenafi H Betrie, James A Brock, Osama F Harraz, Ashley Bush, Guo-Wei He, Mark T Nelson, James A Angus, Christine E Wright, Scott Ayton

Journal article  |  2021  |  NATURE COMMUNICATIONS

Zinc, an abundant transition metal, serves as a signalling molecule in several biological systems. Zinc transporters are genetical..