Levin Kuhlmann

A taxonomy of seizure dynamotypes.

Maria Luisa Saggio, Dakota Crisp, Jared M Scott, Philippa Karoly, Levin Kuhlmann, Mitsuyoshi Nakatani, Tomohiko Murai, Matthias Dümpelmann, Andreas Schulze-Bonhage, Akio Ikeda, Mark Cook, Stephen V Gliske, Jack Lin, Christophe Bernard, Viktor Jirsa, William C Stacey

Journal article  |  2020  |  eLife

Seizures are a disruption of normal brain activity present across a vast range of species and conditions. We introduce an organizi..

Critical slowing down as a biomarker for seizure susceptibility.

Matias I Maturana, Christian Meisel, Katrina Dell, Philippa J Karoly, Wendyl D'Souza, David B Grayden, Anthony N Burkitt, Premysl Jiruska, Jan Kudlacek, Jaroslav Hlinka, Mark J Cook, Levin Kuhlmann, Dean R Freestone

Journal article  |  2020  |  Nature Communications

The human brain has the capacity to rapidly change state, and in epilepsy these state changes can be catastrophic, resulting in lo..

Forecasting cycles of seizure likelihood

Philippa J Karoly, Mark J Cook, Matias Maturana, Ewan S Nurse, Daniel Payne, Benjamin H Brinkmann, David B Grayden, Sonya B Dumanis, Mark P Richardson, Greg A Worrell, Andreas Schulze-Bonhage, Levin Kuhlmann, Dean R Freestone

Journal article  |  2020  |  Epilepsia

OBJECTIVE: Seizure unpredictability is rated as one of the most challenging aspects of living with epilepsy. Seizure likelihood ca..

Ensembling crowdsourced seizure prediction algorithms using long-term human intracranial EEG

Chip Reuben, Philippa Karoly, Dean R Freestone, Andriy Temko, Alexandre Barachant, Feng Li, Gilberto Titericz, Brian W Lang, Daniel Lavery, Kelly Roman, Derek Broadhead, Gareth Jones, Qingnan Tang, Irina Ivanenko, Oleg Panichev, Timothee Proix, Michal Nahlik, Daniel B Grunberg, David B Grayden, Mark J Cook, et al.

Journal article  |  2020  |  Epilepsia

Seizure prediction is feasible, but greater accuracy is needed to make seizure prediction clinically viable across a large group o..

Forecasting Cycles of Seizure Likelihood

Philippa Karoly, Matias Maturana, Mark Cook, Ewan Nurse, Daniel Payne, Benjamin Brinkmann, David Grayden, Sonya Dumanis, Mark Richardson, Greg Worrell, Andreas Schulze-Bonhage, Levin Kuhlmann, Dean Freestone

Journal article  |  2019

Objective: Seizure unpredictability is rated as one of the most challenging aspects of living with epilepsy. Seizure likelihood ca..

Epileptic Seizure Forecasting With Generative Adversarial Networks

Duy Truong Nhan, Levin Kuhlmann, Mohammad Reza Bonyadi, Damien Querlioz, Luping Zhou, Omid Kavehei

Journal article  |  2019  |  IEEE Access

Integer Convolutional Neural Network for Seizure Detection

Duy Truong Nhan, Duy Nguyen Anh, Levin Kuhlmann, Mohammad Reza Bonyadi, Jiawei Yang, Samuel Ippolito, Omid Kavehei

Journal article  |  2018  |  IEEE Journal on Emerging and Selected Topics in Circuits and Systems

Seizure prediction - ready for a new era

Levin Kuhlmann, Klaus Lehnertz, Mark P Richardson, Bjorn Schelter, Hitten P Zaveri

Journal article  |  2018  |  Nature Reviews Neurology

Seizure pathways: A model-based investigation

Philippa J Karoly, Levin Kuhlmann, Daniel Soudry, David B Grayden, Mark J Cook, Dean R Freestone

Journal article  |  2018  |  PLOS COMPUTATIONAL BIOLOGY

Convolutional neural networks for seizure prediction using intracranial and scalp electroencephalogram

Duy Truong Nhan, Duy Nguyen Anh, Levin Kuhlmann, Mohammad Reza Bonyadi, Jiawei Yang, Samuel Ippolito, Omid Kavehei

Journal article  |  2018  |  Neural Networks

Epilepsyecosystem.org: crowd-sourcing reproducible seizure prediction with long-term human intracranial EEG

Levin Kuhlmann, Philippa Karoly, Dean R Freestone, Benjamin H Brinkmann, Andriy Temko, Alexandre Barachant, Feng Li, Gilberto Titericz, Brian W Lang, Daniel Lavery, Kelly Roman, Derek Broadhead, Scott Dobson, Gareth Jones, Qingnan Tang, Irina Ivanenko, Oleg Panichev, Timothee Proix, Michal Nahlik, Daniel B Grunberg, et al.

Journal article  |  2018  |  Brain

Postictal suppression and seizure durations: A patient-specific, long-term iEEG analysis

Daniel E Payne, Philippa J Karoly, Dean R Freestone, Ray Boston, Wendyl D'Souza, Ewan Nurse, Levin Kuhlmann, Mark J Cook, David B Grayden

Journal article  |  2018  |  Epilepsia

Assessing nitrous oxide effect using electroencephalographically-based depth of anesthesia measures cortical state and cortical input

Levin Kuhlmann, David TJ Liley

Journal article  |  2018  |  JOURNAL OF CLINICAL MONITORING AND COMPUTING

Convolutional Neural Networks for Epileptic Seizure Prediction

Matthias Eberlein, Raphael Hildebrand, Ronald Tetzlaff, Nico Hoffmann, Levin Kuhlmann, Benjamin Brinkmann, Jens Mueller

Conference Proceedings  |  2018  |  2018 IEEE International Conference on Bioinformatics and Biomedicine (BIBM)

Recording Brain Electromagnetic Activity During the Administration of the Gaseous Anesthetic Agents Xenon and Nitrous Oxide in Healthy Volunteers

Andria Pelentritou, Levin Kuhlmann, John Cormack, Will Woods, Jamie Sleigh, David Liley

Journal article  |  2018  |  Journal of Visualized Experiments

Supervised learning in automatic channel selection for epileptic seizure detection

Duy Truong Nhan, Levin Kuhlmann, Mohammad Reza Bonyadi, Jiawei Yang, Andrew Faulks, Omid Kavehei

Journal article  |  2017  |  Expert Systems with Applications

The circadian profile of epilepsy improves seizure forecasting

Philippa J Karoly, Hoameng Ung, David B Grayden, Levin Kuhlmann, Kent Leyde, Mark J Cook, Dean R Freestone

Journal article  |  2017  |  BRAIN

Tracking Electroencephalographic Changes Using Distributions of Linear Models: Application to Propofol-Based Depth of Anesthesia Monitoring

Levin Kuhlmann, Jonathan H Manton, Bjorn Heyse, Hugo EM Vereecke, Tarmo Lipping, Michel MRF Struys, David TJ Liley

Journal article  |  2017  |  IEEE TRANSACTIONS ON BIOMEDICAL ENGINEERING

Probing to Observe Neural Dynamics Investigated with Networked Kuramoto Oscillators

Elma O'Sullivan-Greene, Levin Kuhlmann, Ewan S Nurse, Dean R Freestone, David B Grayden, Mark Cook, Anthony Burkitt, Iven Mareels

Journal article  |  2017  |  International Journal of Neural Systems

Statistical Performance Analysis of Data-Driven Neural Models

Dean R Freestone, Kelvin J Layton, Levin Kuhlmann, Mark J Cook

Conference Proceedings  |  2017  |  International Journal of Neural Systems

Introduction: Special Issue on Epilepsy Mechanisms, Models, Prediction and Control

Levin Kuhlmann, David B Grayden, Mark J Cook

Journal article  |  2017  |  International Journal of Neural Systems

Seizure prediction and observability of EEG sources

E O'Sullivan-Greene, L Kuhlmann, A Varsavsky, DB Grayden, AN Burkitt, IMY Mareels

Book Chapter  |  2016

Neural mass model-based tracking of anesthetic brain states

L Kuhlmann, DR Freestone, JH Manton, B Heyse, HEM Vereecke, T Lipping, MMRF Struys, DTJ Liley

Journal article  |  2016  |  NeuroImage

Abstract Neural mass model-based tracking of brain states from electroencephalographic signals holds the promise of simultaneously..

Seizure Prediction: Science Fiction or Soon to Become Reality?

Dean R Freestone, Philippa J Karoly, Andre DH Peterson, Levin Kuhlmann, Alan Lai, Farhad Goodarzy, Mark J Cook

Journal article  |  2015  |  CURRENT NEUROLOGY AND NEUROSCIENCE REPORTS

Parameter and State Estimation of Nonlinear Systems Using a Multi-Observer Under the Supervisory Framework

Michelle S Chong, Dragan Nesic, Romain Postoyan, Levin Kuhlmann

Journal article  |  2015  |  IEEE Transactions on Automatic Control

Role of Multiple-Scale Modeling of Epilepsy in Seizure Forecasting

Levin Kuhlmann, David B Grayden, Fabrice Wendling, Steven J Schiff

Journal article  |  2015  |  Journal of Clinical Neurophysiology

Alterations in the Functional Connectivity of Frontal Lobe Networks Preceding Emergence Delirium in Children

Jessica C Martin, David TJ Liley, A Simon Harvey, Levin Kuhlmann, Jamie W Sleigh, Andrew J Davidson

Journal article  |  2014  |  Anesthesiology

Observability limits for networked oscillators

Elma O'Sullivan-Greene, Iven Mareels, Levin Kuhlmann, Anthony Burkitt

Journal article  |  2014  |  Automatica

Approximate, Computationally Efficient Online Learning in Bayesian Spiking Neurons

Levin Kuhlmann, Michael Hauser-Raspe, Jonathan H Manton, David B Grayden, Jonathan Tapson, Andre van Schaik

Journal article  |  2014  |  Neural Computation

State and parameter estimation of nonlinear systems: a multi-observer approach

Michelle S Chong, Dragan Nesic, Romain Postoyan, Levin Kuhlmann

Conference Proceedings  |  2014  |  53rd IEEE Conference on Decision and Control

Extending Communication for Patients with Disorders of Consciousness

Xingwen Liang, Levin Kuhlmann, Leigh A Johnston, David B Grayden, Simon Vogrin, Rosemary Crossley, Karen Fuller, Mark Lourensz, Mark J Cook

Journal article  |  2014  |  Journal of Neuroimaging

Mechanisms of Seizure Propagation in 2-Dimensional Centre-Surround Recurrent Networks

David Hall, Levin Kuhlmann

Journal article  |  2013  |  PLoS One

Modulation of Functional EEG Networks by the NMDA Antagonist Nitrous Oxide

Levin Kuhlmann, Brett L Foster, David TJ Liley

Journal article  |  2013  |  PLoS One

PATIENT-SPECIFIC NEURAL MASS MODELING - STOCHASTIC AND DETERMINISTIC METHODS

DR Freestone, L Kuhlmann, MS Chong, D Nesic, DB Grayden, P Aram, R Postoyan, MJ CooK

Book Chapter  |  2013

A robust circle criterion observer with application to neural mass models

Michelle Chong, Romain Postoyan, Dragan Nesic, Levin Kuhlmann, Andrea Varsavsky

Journal article  |  2012  |  Automatica

Estimating the unmeasured membrane potential of neuronal populations from the EEG using a class of deterministic nonlinear filters

Michelle Chong, Romain Postoyan, Dragan Nesic, Levin Kuhlmann, Andrea Varsavsky

Journal article  |  2012  |  Journal of Neural Engineering

Online Learning in Bayesian Spiking Neurons

Levin Kuhlmann, Michael Hauser-Raspe, Jonathan Manton, David B Grayden, Jonathan Tapson, Andre van Schaik

Conference Proceedings  |  2012  |  Proceedings of WCCI 2012 IEEE World Congress on Computational Intelligence

Parameter and state estimation for a class of neural mass models

Romain Postoyan, Michelle Chong, Dragan Nesic, Levin Kuhlmann

Conference Proceedings  |  2012  |  Proceedings of the 51st IEEE Conference on Decision and Control

Convergence analysis of efficient online learning in Bayesian spiking neurons.

Andre Van Schaik, Levin Kuhlmann, Michael Hauser-Raspe, Jonathan Manton, Jonathan Tapson, David B Grayden

Journal article  |  2012  |  BMC Neuroscience

Electrical probing of cortical excitability in patients with epilepsy

Dean R Freestone, Levin Kuhlmann, David B Grayden, Anthony N Burkitt, Alan Lai, Timothy S Nelson, Simon Vogrin, Michael Murphy, Wendyl D'Souza, Radwa Badawy, Dragan Nesic, Mark J Cook

Journal article  |  2011  |  Epilepsy and Behavior

A circle criterion observer for estimating the unmeasured membrane potential of neuronal populations

M Chong, R Postoyan, D Nešić, L Kuhlmann, A Varsavsky

Conference Proceedings  |  2011  |  Proceedings of Australian Control Conference

Matching pursuit based removal of cardiac pulse-related artifacts in EEG/fMRI

R Schneider, S Lau, L Kuhlmann, S Vogrin, M Gratkowski, M Cook, J Haueisen

Journal article  |  2011  |  World Acad. Sci. Eng. Technol.

A nonlinear estimator for the activity of neuronal populations in the hippocampus

M Chong, R Postoyan, D Nešić, L Kuhlmann, A Varsavsky

Conference Proceedings  |  2011  |  Proceedings of the 18th IFAC World Congress

Probing for Cortical Excitability

Dean R Freestone, Anthony N Burkitt, Alan Lai, Timothy S Nelson, David B Grayden, Simon Vogrin, Michael Murphy, Wendyl D'Souza, Radwa Badawy, Levin Kuhlmann, Mark J Cook

Conference Proceedings  |  2011  |  33rd Annual International IEEE EMBC Conference

A computational study of how orientation bias in the lateral geniculate nucleus can give rise to orientation selectivity in primary visual cortex.

Levin Kuhlmann, Trichur R Vidyasagar

Journal article  |  2011  |  Frontiers in Systems Neuroscience

Controversy remains about how orientation selectivity emerges in simple cells of the mammalian primary visual cortex. In this pape..

Matching pursuit based removal of cardiac pulse-related artifacts in EEG/fMRI

R Schneider, S Lau, L Kuhlmann, S Vogrin, M Gratkowski, M Cook, J Haueisen

Journal article  |  2011  |  World Academy of Science, Engineering and Technology. Proceedings

Patient-specific bivariate-synchrony-based seizure prediction for short prediction horizons

Levin Kuhlmann, Dean Freestone, Alan Lai, Anthony N Burkitt, Karen Fuller, David B Grayden, Linda Seiderer, Simon Vogrin, Iven MY Mareels, Mark J Cook

Journal article  |  2010  |  Epilepsy Research

The perturbation response and power spectrum of a mean-field of IF neurons with inhomogeneous inputs.

Andre DH Peterson, Hamish Meffin, Anthony N Burkitt, Iven MY Mareels, David B Grayden, Levin Kuhlmann, Mark J Cook

Journal article  |  2010  |  BMC Neuroscience

Seizure Detection Using Seizure Probability Estimation: Comparison of Features Used to Detect Seizures

Levin Kuhlmann, Anthony N Burkitt, Mark J Cook, Karen Fuller, David B Grayden, Linda Seiderer, Iven MY Mareels

Journal article  |  2009  |  Annals of Biomedical Engineering

Analysis of the power spectra, autocorrelation function and EEG time-series signal of a network of leaky integrate-and-fire neurons with conductance-based synapses

Andre DH Peterson, Hamish Meffin, Anthony N Burkitt, Iven MY Mareels, David B Grayden, Levin Kuhlmann, Mark J Cook

Journal article  |  2009  |  BMC Neuroscience

210. Spatiotemporal patterns of high frequency oscillation from intracranial EEG before and during seizure

Karen Fuller, Dean Freestone, Simon Vogrin, Alan Lai, Levin Kuhlmann, David Grayden, Anthony Burkitt, Mark Cook

Journal article  |  2009  |  Journal of Clinical Neuroscience

A Paradigm for Epileptic Seizure Prediction Using a Coupled Oscillator Model of the Brain

Elma O'Sullivan-Greene, Iven Mareels, Dean Freestone, Levin Kulhmann, Anthony Burkitt

Conference Proceedings  |  2009  |  Proceedings of the 31st Annual International Conference of the IEEE Engineering in Medicine and Biology Society

Observability Issues in Networked Clocks with Applications to Epilepsy

Elma O'Sullivan-Greene, Iven Mareels, Anthony Burkitt, Levin Kulhmann

Conference Proceedings  |  2009  |  Proceedings of the 48th IEEE Conference on Decision and Control held jointly with the 2009 28th Chinese Control Conference

Correlation analysis of seizure detection features

L Kuhlmann, MJ Cook, K Fuller, DB Grayden, AN Burkitt, IMY Mareels

Conference Proceedings  |  2008  |  ISSNIP 2008. Proceedings of the 4th International Conference on Intelligent Sensors, Sensor Networks and Information Processing

A neural model of 3D shape-from-texture: Multiple-scale filtering, boundary grouping, and surface filling-in

Stephen Grossberg, Levin Kuhlmann, Ennio Mingolla

Journal article  |  2007  |  Vision Research

Introduction: International Trade and Human Rights: Foundations and Conceptual Issues

C Breining-Kaufmann, Michelle Foster

Book Chapter  |  2006

Summation of spatiotemporal input patterns in leaky integrate-and-fire neurons: Application to neurons in the cochlear nucleus receiving converging auditory nerve fiber input

L Kuhlmann, AN Burkitt, A Paolini, GM Clark

Journal article  |  2002  |  JOURNAL OF COMPUTATIONAL NEUROSCIENCE

Measurement of the limiting equivalent conductivities and mobilities of the most prevalent ionic species of EGTA (EGTA(2-) and EGTA(3-)) for use in electrophysiological experiments

A Keramidas, L Kuhlmann, AJ Moorhouse, PH Barry

Journal article  |  1999  |  Journal of Neuroscience Methods