Soren Christensen

A machine-learning framework for robust and reliable prediction of short- and long-term treatment response in initially antipsychotic-naive schizophrenia patients based on multimodal neuropsychiatric data

Karen S Ambrosen, Martin W Skjerbaek, Jonathan Foldager, Martin C Axelsen, Nikolaj Bak, Lars Arvastson, Soren R Christensen, Louise B Johansen, Jayachandra M Raghava, Bob Oranje, Egill Rostrup, Mette O Nielsen, Merete Osler, Birgitte Fagerlund, Christos Pantelis, Bruce J Kinon, Birte Y Glenthoj, Lars K Hansen, Bjorn H Ebdrup

Journal article  |  2020  |  TRANSLATIONAL PSYCHIATRY

The reproducibility of machine-learning analyses in computational psychiatry is a growing concern. In a multimodal neuropsychiatri..

Comparison of Tmax values between full- and half-dose gadolinium perfusion studies

Soren Christensen, Shalini Amukotuwa, Maarten G Lansberg, Stephanie Kemp, Jeremy J Heit, Michael Mlynash, Michael P Marks, Greg W Albers, Roland Bammer

Journal article  |  2020  |  JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM

AHA guidelines recommend use of perfusion imaging for patient selection in the 6-24 h window. Recently, the safety of gadolinium-b..

Artificial Neural Network Computer Tomography Perfusion Prediction of Ischemic Core

Aimen S Kasasbeh, Soren Christensen, Mark W Parsons, Bruce Campbell, Gregory W Albers, Maarten G Lansberg

Journal article  |  2019  |  STROKE

Background and Purpose- Computed tomography perfusion (CTP) is a useful tool in the evaluation of acute ischemic stroke, where it ..

Thrombolysis Guided by Perfusion Imaging up to 9 Hours after Onset of Stroke

H Ma, BCV Campbell, MW Parsons, L Churilov, CR Levi, C Hsu, TJ Kleinig, T Wijeratne, S Curtze, HM Dewey, F Miteff, C-H Tsai, J-T Lee, TG Phan, N Mahant, M-C Sun, M Krause, J Sturm, R Grimley, C-H Chen, et al.

Journal article  |  2019  |  NEW ENGLAND JOURNAL OF MEDICINE

BACKGROUND: The time to initiate intravenous thrombolysis for acute ischemic stroke is generally limited to within 4.5 hours after..

A Comparison of Relative Time to Peak and Tmax for Mismatch-Based Patient Selection

Anke Wouters, Soren Christensen, Matus Straka, Michael Mlynash, John Liggins, Roland Bammer, Vincent Thijs, Robin Lemmens, Gregory W Albers, Maarten G Lansberg

Journal article  |  2017  |  FRONTIERS IN NEUROLOGY

BACKGROUND AND PURPOSE: The perfusion-weighted imaging (PWI)/diffusion-weighted imaging (DWI) mismatch profile is used to select p..

A benchmarking tool to evaluate computer tomography perfusion infarct core predictions against a DWI standard

Carlo W Cereda, Soren Christensen, Bruce CV Campbell, Nishant K Mishra, Michael Mlynash, Christopher Levi, Matus Straka, Max Wintermark, Roland Bammer, Gregory W Albers, Mark W Parsons, Maarten G Lansberg

Journal article  |  2016  |  JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM

Differences in research methodology have hampered the optimization of Computer Tomography Perfusion (CTP) for identification of th..

Worse stroke outcome in atrial fibrillation is explained by more severe hypoperfusion, infarct growth, and hemorrhagic transformation

Hans TH Tu, Bruce CV Campbell, Soren Christensen, Patricia M Desmond, Deidre A De Silva, Mark W Parsons, Leonid Churilov, Maarten G Lansberg, Michael Mlynash, Jean-Marc Olivot, Matus Straka, Roland Bammer, Gregory W Albers, Geoffrey A Donnan, Stephen M Davis

Journal article  |  2015  |  INTERNATIONAL JOURNAL OF STROKE

BACKGROUND: Atrial fibrillation is associated with greater baseline neurological impairment and worse outcomes following ischemic ..

STroke imAging pRevention and treatment (START): A longitudinal stroke cohort study: Clinical trials protocol

Leeanne M Carey, Sheila Crewther, Olivier Salvado, Thomas Linden, Alan Connelly, William Wilson, David W Howells, Leonid Churilov, Henry Ma, Tamara Tse, Stephen Rose, Susan Palmer, Pierrick Bougeat, Bruce CV Campbell, Soren Christensen, S Lance Macaulay, Jenny Favaloro, Victoria O' Collins, Simon McBride, Susan Bates, et al.

Journal article  |  2015  |  INTERNATIONAL JOURNAL OF STROKE

RATIONALE: Stroke and poststroke depression are common and have a profound and ongoing impact on an individual's quality of life. ..

Validity of Acute Stroke Lesion Volume Estimation by Diffusion-Weighted Imaging-Alberta Stroke Program Early Computed Tomographic Score Depends on Lesion Location in 496 Patients With Middle Cerebral Artery Stroke

Julian Schroeder, Bastian Cheng, Martin Ebinger, Martin Koehrmann, Ona Wu, Dong-Wha Kang, David S Liebeskind, Thomas Tourdias, Oliver C Singer, Soren Christensen, Bruce Campbell, Marie Luby, Steven Warach, Jens Fiehler, Jochen B Fiebach, Christian Gerloff, Goetz Thomalla

Journal article  |  2014  |  STROKE

BACKGROUND AND PURPOSE: Alberta Stroke Program Early Computed Tomographic Score (ASPECTS) has been used to estimate diffusion-weig..

Lesion segmentation from multimodal MRI using random forest following ischemic stroke

Jhimli Mitra, Pierrick Bourgeat, Jurgen Fripp, Soumya Ghose, Stephen Rose, Olivier Salvado, Alan Connelly, Bruce Campbell, Susan Palmer, Gagan Sharma, Soren Christensen, Leeanne Carey

Journal article  |  2014  |  NEUROIMAGE

Understanding structure-function relationships in the brain after stroke is reliant not only on the accurate anatomical delineatio..