Leigh Johnston

Mapping the association between tau-PET and Aβ-amyloid-PET using deep learning.

Gihan P Ruwanpathirana, Robert C Williams, Colin L Masters, Christopher C Rowe, Leigh A Johnston, Catherine E Davey

Journal article  |  2022  |  Sci Rep

In Alzheimer's disease, the molecular pathogenesis of the extracellular Aβ-amyloid (Aβ) instigation of intracellular tau accumulat..

Long-term structural brain changes in adult rats after mild ischaemic stroke

Warda Syeda, Charlotte M Ermine, Mohamed Salah Khilf, David Wright, Vanessa H Brait, Jess Nithianantharajah, Scott Kolbe, Leigh A Johnston, Lachlan H Thompson, Amy Brodtmann

Journal article  |  2022  |  BRAIN COMMUNICATIONS

Preclinical studies of remote degeneration have largely focused on brain changes over the first few days or weeks after stroke. Ac..

Cortico-cognition coupling in treatment resistant schizophrenia

Warda T Syeda, Cassandra MJ Wannan, Antonia H Merritt, Jayachandra M Raghava, Mahesh Jayaram, Dennis Velakoulis, Tina D Kristensen, Rigas Filippos Soldatos, Shane Tonissen, Naveen Thomas, Karen S Ambrosen, Mikkel E Sorensen, Birgitte Fagerlund, Egill Rostrup, Birte Y Glenthoj, Efstratios Skafidas, Chad A Bousman, Leigh A Johnston, Ian Everall, Bjorn H Ebdrup, et al.

Journal article  |  2022  |  NEUROIMAGE-CLINICAL

BACKGROUND: Brain structural alterations and cognitive dysfunction are independent predictors for poor clinical outcome in schizop..

Is Public Data Enough? A Comparison of Public and Institutional Deep Learning Models for Segmentation of 17 Organs-At-Risk in the Head and Neck

Brett Clark, Nicholas Hardcastle, Price Jackson, Leigh Johnston, James Korte

Conference Proceedings  |  2022  |  MEDICAL PHYSICS

The "Spin-3/2 Bloch Equation": System matrix formalism of excitation, relaxation, and off-resonance effects in biological tissue

Chengchuan Wu, Yasmin Blunck, Leigh A Johnston

Journal article  |  2022  |  MAGNETIC RESONANCE IN MEDICINE

PURPOSE: This work proposes "Spin-3/2 Bloch Equation" (SBE), a consolidated formalism for spin-3/2 dynamics in biological environm..

Ultrahigh field brain magnetic resonance imaging using semiadiabatic radiofrequency pulses

Roger Ordidge, Yasmin Blunck, Rebecca Glarin, Bradford Moffat, Leigh Johnston

Journal article  |  2021  |  NMR IN BIOMEDICINE

Great attention is being paid to solving, or mitigating, the technical problems associated with MRI at ultrahigh field strengths o..

Longitudinal hippocampal volumetric changes in mice following brain infarction

Vanessa H Brait, David K Wright, Mohsen Nategh, Alexander Oman, Warda T Syeda, Charlotte M Ermine, Katrina R O'Brien, Emilio Werden, Leonid Churilov, Leigh A Johnston, Lachlan H Thompson, Jess Nithianantharajah, Katherine A Jackman, Amy Brodtmann

Journal article  |  2021  |  SCIENTIFIC REPORTS

Hippocampal atrophy is increasingly described in many neurodegenerative syndromes in humans, including stroke and vascular cogniti..

A gyrification analysis approach based on Laplace Beltrami eigenfunction level sets

Rosita Shishegar, Fabrizio Pizzagalli, Nellie Georgiou-Karistianis, Gary F Egan, Neda Jahanshad, Leigh A Johnston

Journal article  |  2021  |  NeuroImage

An accurate measure of the complexity of patterns of cortical folding or gyrification is necessary for understanding normal brain ..

Correcting for Non-stationarity in BOLD-fMRI Connectivity Analyses

Catherine E Davey, David B Grayden, Leigh A Johnston

Journal article  |  2021  |  FRONTIERS IN NEUROSCIENCE

In this work fMRI BOLD datasets are shown to contain slice-dependent non-stationarities. A model containing slice-dependent, non-s..

QSMART: Quantitative susceptibility mapping artifact reduction technique

Negin Yaghmaie, Warda T Syeda, Chengchuan Wu, Yicheng Zhang, Tracy D Zhang, Emma L Burrows, Amy Brodtmann, Bradford A Moffat, David K Wright, Rebecca Glarin, Scott Kolbe, Leigh A Johnston

Journal article  |  2021  |  NEUROIMAGE

PURPOSE: Quantitative susceptibility mapping (QSM) is a novel MR technique that allows mapping of tissue susceptibility values fro..