Elizabeth Williams

A molecular portrait of epithelial-mesenchymal plasticity in prostate cancer associated with clinical outcome.

Nataly Stylianou, Melanie L Lehman, Chenwei Wang, Atefeh Taherian Fard, Anja Rockstroh, Ladan Fazli, Lidija Jovanovic, Micheal Ward, Martin C Sadowski, Abhishek S Kashyap, Ralph Buttyan, Martin E Gleave, Thomas F Westbrook, Elizabeth D Williams, Jennifer H Gunter, Colleen C Nelson, Brett G Hollier

Journal article  |  2019  |  Oncogene

The propensity of cancer cells to transition between epithelial and mesenchymal phenotypic states via the epithelial-mesenchymal t..

Movember GAP1 PDX project: An international collection of serially transplantable prostate cancer patient-derived xenograft (PDX) models

Nora M Navone, Wytske M van Weerden, Robert L Vessella, Elizabeth D Williams, Yuzhuo Wang, John T Isaacs, Holly M Nguyen, Zoran Culig, Gabri van der Pluijm, Cyril A Rentsch, Rute B Marques, Corrina MA de Ridder, Lukas Bubendorf, George N Thalmann, William Nathaniel Brennen, Frederic R Santer, Patrizia L Moser, Peter Shepherd, Eleni Efstathiou, Hui Xue, et al.

Journal article  |  2018  |  The Prostate

Humanization of the Prostate Microenvironment Reduces Homing of PC3 Prostate Cancer Cells to Human Tissue-Engineered Bone

Jacqui A McGovern, Abbas Shafiee, Ferdinand Wagner, Christoph A Lahr, Marietta Landgraf, Christoph Meinert, Elizabeth D Williams, Pamela J Russell, Judith A Clements, Daniela Loessner, Boris M Holzapfel, Gail P Risbridger, Dietmar W Hutmacher

Journal article  |  2018  |  Cancers

High mammographic density in women is associated with protumor inflammation

Cecilia W Huo, Prue Hill, Grace Chew, Paul J Neeson, Heloise Halse, Elizabeth D Williams, Michael A Henderson, Erik W Thompson, Kara L Britt

Journal article  |  2018  |  Breast Cancer Research

Alterations of tumor vasculature and hypoxia of prostate cancer xenografts in vivo assessed by ultrasound and photoacoustic imaging

Q Hu, E Ratther, ED Williams, K Sweeney, CC Nelson, PJ Russell, BG Hollier

Conference Proceedings  |  2018  |  BJU INTERNATIONAL

Neuropilin-1 is upregulated in the adaptive response of prostate tumors to androgen-targeted therapies and is prognostic of metastatic progression and patient mortality

BWC Tse, M Volpert, E Ratther, N Stylianou, M Nouri, K McGowan, ML Lehman, SJ McPherson, M Roshan-Moniri, MS Butler, J Caradec, CY Gregory-Evans, J McGovern, R Das, M Takhar, N Erho, M Alshalafa, E Davicioni, EM Schaeffer, RB Jenkins, et al.

Journal article  |  2017  |  Oncogene

MicroRNA-194 Promotes Prostate Cancer Metastasis by Inhibiting SOCS2

Rajdeep Das, Philip A Gregory, Rayzel C Fernandes, Iza Denis, Qingqing Wang, Scott L Townley, Shuang G Zhao, Adrienne R Hanson, Marie A Pickering, Heather K Armstrong, Noor A Lokman, Esmaeil Ebrahimie, Elai Davicioni, Robert B Jenkins, R Jeffrey Karnes, Ashley E Ross, Robert B Den, Eric A Klein, Kim N Chi, Hayley S Ramshaw, et al.

Journal article  |  2017  |  Cancer Research

Prostate Cancer Metastasis

C Nicholson, I Vela, ED Williams

Book Chapter  |  2017

Restoration of tumor suppression in prostate cancer by targeting the E3 ligase E6AP

PJ Paul, D Raghu, A-L Chan, T Gulati, L Lambeth, E Takano, MJ Herold, J Hagekyriakou, RL Vessella, C Fedele, M Shackleton, ED Williams, S Fox, S Williams, S Haupt, C Gamell, Y Haupt

Journal article  |  2016  |  Oncogene

Mammographically dense human breast tissue stimulates MCF10DCIS.com progression to invasive lesions and metastasis

Cecilia W Huo, Mark Waltham, Christine Khoo, Stephen B Fox, Prue Hill, Shou Chen, Grace L Chew, John T Price, Chau H Nguyen, Elizabeth D Williams, Michael Henderson, Erik W Thompson, Kara L Britt

Journal article  |  2016  |  Breast Cancer Research

Genome-wide gain-of-function screen for genes that induce epithelial-to-mesenchymal transition in breast cancer

Dubravka Skalamera, Mareike Dahmer-Heath, Alexander J Stevenson, Cletus Pinto, Esha T Shah, Sheena M Daignault, Nur Akmarina BM Said, Melissa Davis, Nikolas K Haass, Elizabeth D Williams, Brett G Hollier, Erik W Thompson, Brian Gabrielli, Thomas J Gonda

Journal article  |  2016  |  Oncotarget

Methotrexate-Conjugated PEGylated Dendrimers Show Differential Patterns of Deposition and Activity in Tumor-Burdened Lymph Nodes after Intravenous and Subcutaneous Administration in Rats

Lisa M Kaminskas, Victoria M McLeod, David B Ascher, Gemma M Ryan, Seth Jones, John M Haynes, Natalie L Trevaskis, Linda J Chan, Erica K Sloan, Bentamin A Finnin, Mark Williamson, Tony Velkov, Elizabeth D Williams, Brian D Kelly, David J Owen, Christopher JH Porter

Journal article  |  2015  |  Molecular Pharmaceutics

Tetraspanins as regulators of the tumour microenvironment: implications for metastasis and therapeutic strategies

S Detchokul, ED Williams, MW Parker, AG Frauman

Journal article  |  2014  |  British Journal of Pharmacology

Whole-Genome Multiparametric Screening to Identify Modulators of Epithelial-to-Mesenchymal Transition

Nur Akmarina BM Said, Cathryn M Gould, Kurt Lackovic, Kaylene J Simpson, Elizabeth D Williams

Journal article  |  2014  |  ASSAY and Drug Development Technologies

Isolation of human lymphatic malformation endothelial cells, their in vitro characterization and in vivo survival in a mouse xenograft model

Zerina Lokmic, Geraldine M Mitchell, Nicholas Koh Wee Chong, Jacqueline Bastiaanse, Yi-Wen Gerrand, Yiping Zeng, Elizabeth D Williams, Anthony J Penington

Journal article  |  2014  |  Angiogenesis

Androgen-targeted therapy-induced epithelial mesenchymal plasticity and neuroendocrine transdifferentiation in prostate cancer: an opportunity for intervention.

Mannan Nouri, Ellca Ratther, Nataly Stylianou, Colleen C Nelson, Brett G Hollier, Elizabeth D Williams

Journal article  |  2014  |  Frontiers in Oncology

Androgens regulate biological pathways to promote proliferation, differentiation, and survival of benign and malignant prostate ti..

ATF3 Suppresses Metastasis of Bladder Cancer by Regulating Gelsolin-Mediated Remodeling of the Actin Cytoskeleton

Xiangliang Yuan, Liang Yu, Junhua Li, Guohua Xie, Tingting Rong, Liang Zhang, Jianhua Chen, Qiaohong Meng, Aaron T Irving, Die Wang, Elizabeth D Williams, Jun-Ping Liu, Anthony J Sadler, Bryan RG Williams, Lisong Shen, Dakang Xu

Journal article  |  2013  |  Cancer Research

Strategies and Challenges for Systematically Mapping Biologically Significant Molecular Pathways Regulating Carcinoma Epithelial-Mesenchymal Transition

Nur Akmarina BM Said, Kaylene J Simpson, Elizabeth D Williams

Journal article  |  2013  |  Cells Tissues Organs

EMT and MET in carcinoma - clinical observations, regulatory pathways and new models

Erik W Thompson, Elizabeth D Williams

Journal article  |  2008  |  Clinical and Experimental Metastasis

Mesenchymal to epithelial transition in development and disease

Christine L Chaffer, Erik W Thompson, Elizabeth D Williams

Journal article  |  2007  |  Cells Tissues Organs

PPARγ-independent induction of growth arrest and apoptosis in prostate and bladder carcinoma

Christine L Chaffer, David M Thomas, Erik W Thompson, Elizabeth D Williams

Journal article  |  2006  |  BMC Cancer

Mesenchymal-to-epithelial transition facilitates bladder cancer metastasis: Role of fibroblast growth factor receptor-2

Christine L Chaffer, Janelle P Brennan, John L Slavin, Tony Blick, Erik W Thompson, Elizabeth D Williams

Journal article  |  2006  |  Cancer Research

Tumor-induced activation of lymphatic endothelial cells via vascular endothelial growth factor receptor-2 is critical for prostate cancer lymphatic metastasis

Yiping Zeng, Kenneth Opeskin, Jeremy Goad, Elizabeth D Williams

Journal article  |  2006  |  Clinical Cancer Research

Lymphatics in the alimentary tract of children in health and disease: Study on mucosal biopsies using the monoclonal antibody D2-40

YP Zeng, FH Wang, ED Williams, CW Chow

Journal article  |  2005  |  Pediatric and Developmental Pathology

BM18: A novel androgen-dependent human prostate cancer xenograft model derived from a bone metastasis

DR McCulloch, K Opeskin, EW Thompson, ED Williams

Journal article  |  2005  |  The Prostate

Upregulation of matrix metalloproteinases (MMPs) in breast cancer xenografts: A major induction of stromal MMP-13

MA Lafleur, AF Drew, EL de Sousa, T Blick, M Bills, EC Walker, ED Williams, M Waltham, EW Thompson

Journal article  |  2005  |  International Journal of Cancer

Interleukin-6 is a potent inducer of S100P, which is up-regulated in androgen-refractory and metastatic prostate cancer

A Hammacher, EW Thompson, ED Williams

Journal article  |  2005  |  International Journal of Biochemistry and Cell Biology

Upregulated MT1-MMP/TIMP-2 axis in the TSU-Pr1-B1/B2 model of metastatic progression in transitional cell carcinoma of the bladder

CL Chaffer, B Dopheide, DR McCulloch, AB Lee, JM Moseley, EW Thompson, ED Williams

Journal article  |  2005  |  Clinical and Experimental Metastasis

Expression and localization of GLUT1 and GLUT12 in prostate carcinoma

JD Chandler, ED Williams, JL Slavin, JD Best, S Rogers

Journal article  |  2003  |  Cancer

Expression and localisation of GLUT1 and GLUT12 glucose transporters in the pregnant and lactating rat mammary gland

ML Macheda, ED Williams, JD Best, ME Wlodek, S Rogers

Journal article  |  2003  |  Cell and Tissue Research

Second-harmonic generation from biological tissues: Effect of excitation wavelength

XY Deng, ED Williams, EW Thompson, X Gan, M Gu

Journal article  |  2002  |  Scanning