Elizabeth Williams

Integrin alpha-2 and beta-1 expression increases through multiple generations of the EDW01 patient-derived xenograft model of breast cancer-insight into their role in epithelial mesenchymal transition in vivo gained from an in vitro model system

Razan Wafai, Elizabeth D Williams, Emma de Souza, Peter T Simpson, Amy E McCart Reed, Jamie R Kutasovic, Mark Waltham, Cameron E Snell, Tony Blick, Erik W Thompson, Honor J Hugo

Journal article  |  2020  |  Breast Cancer Research

BACKGROUND: Breast cancers acquire aggressive capabilities via epithelial to mesenchymal transition (EMT), in which various integr..

Cancer-associated fibroblasts of the prostate promote a compliant and more invasive phenotype in benign prostate epithelial cells

A Jaeschke, A Jacobi, MG Lawrence, GP Risbridger, M Frydenberg, ED Williams, I Vela, DW Hutmacher, LJ Bray, A Taubenberger

Journal article  |  2020  |  Materials Today Bio

Reciprocal interactions between prostate epithelial cells and their adjacent stromal microenvironment not only are essential for t..

The clinical efficacy of PSMA PET/MRI in biochemically recurrent prostate cancer compared with standard of care imaging modalities and confirmatory histopathology: results of a single-centre, prospective clinical trial.

A Joshi, MJ Roberts, M Perera, E Williams, H Rhee, D Pryor, M Lehman, P Heathcote, S Wood, J Coucher, S Gustafson, K Miles, I Vela

Journal article  |  2020  |  Clinical & Experimental Metastasis

Prospective evidence for the clinical role and efficacy of prostate specific membrane antigen (PSMA) positron emission tomography ..

A molecular portrait of epithelial-mesenchymal plasticity in prostate cancer associated with clinical outcome.

Nataly Stylianou, Melanie L Lehman, Chenwei Wang, Atefeh Taherian Fard, Anja Rockstroh, Ladan Fazli, Lidija Jovanovic, Micheal Ward, Martin C Sadowski, Abhishek S Kashyap, Ralph Buttyan, Martin E Gleave, Thomas F Westbrook, Elizabeth D Williams, Jennifer H Gunter, Colleen C Nelson, Brett G Hollier

Journal article  |  2019  |  Oncogene

The propensity of cancer cells to transition between epithelial and mesenchymal phenotypic states via the epithelial-mesenchymal t..

Movember GAP1 PDX project: An international collection of serially transplantable prostate cancer patient-derived xenograft (PDX) models

Nora M Navone, Wytske M van Weerden, Robert L Vessella, Elizabeth D Williams, Yuzhuo Wang, John T Isaacs, Holly M Nguyen, Zoran Culig, Gabri van der Pluijm, Cyril A Rentsch, Rute B Marques, Corrina MA de Ridder, Lukas Bubendorf, George N Thalmann, William Nathaniel Brennen, Frederic R Santer, Patrizia L Moser, Peter Shepherd, Eleni Efstathiou, Hui Xue, et al.

Journal article  |  2018  |  The Prostate

Humanization of the Prostate Microenvironment Reduces Homing of PC3 Prostate Cancer Cells to Human Tissue-Engineered Bone

Jacqui A McGovern, Abbas Shafiee, Ferdinand Wagner, Christoph A Lahr, Marietta Landgraf, Christoph Meinert, Elizabeth D Williams, Pamela J Russell, Judith A Clements, Daniela Loessner, Boris M Holzapfel, Gail P Risbridger, Dietmar W Hutmacher

Journal article  |  2018  |  Cancers

High mammographic density in women is associated with protumor inflammation

Cecilia W Huo, Prue Hill, Grace Chew, Paul J Neeson, Heloise Halse, Elizabeth D Williams, Michael A Henderson, Erik W Thompson, Kara L Britt

Journal article  |  2018  |  Breast Cancer Research

Alterations of tumor vasculature and hypoxia of prostate cancer xenografts in vivo assessed by ultrasound and photoacoustic imaging

Q Hu, E Ratther, ED Williams, K Sweeney, CC Nelson, PJ Russell, BG Hollier

Conference Proceedings  |  2018  |  BJU INTERNATIONAL

Neuropilin-1 is upregulated in the adaptive response of prostate tumors to androgen-targeted therapies and is prognostic of metastatic progression and patient mortality

BWC Tse, M Volpert, E Ratther, N Stylianou, M Nouri, K McGowan, ML Lehman, SJ McPherson, M Roshan-Moniri, MS Butler, J Caradec, CY Gregory-Evans, J McGovern, R Das, M Takhar, N Erho, M Alshalafa, E Davicioni, EM Schaeffer, RB Jenkins, et al.

Journal article  |  2017  |  Oncogene

MicroRNA-194 Promotes Prostate Cancer Metastasis by Inhibiting SOCS2

Rajdeep Das, Philip A Gregory, Rayzel C Fernandes, Iza Denis, Qingqing Wang, Scott L Townley, Shuang G Zhao, Adrienne R Hanson, Marie A Pickering, Heather K Armstrong, Noor A Lokman, Esmaeil Ebrahimie, Elai Davicioni, Robert B Jenkins, R Jeffrey Karnes, Ashley E Ross, Robert B Den, Eric A Klein, Kim N Chi, Hayley S Ramshaw, et al.

Journal article  |  2017  |  Cancer Research