Andrew Jobling

The Contribution of Microglia to the Development and Maturation of the Visual System

Michael A Dixon, Ursula Greferath, Erica L Fletcher, Andrew I Jobling

Journal article  |  2021  |  Frontiers in Cellular Neuroscience

Microglia, the resident immune cells of the central nervous system (CNS), were once considered quiescent cells that sat in readine..

Subthreshold Nano-Second Laser Treatment and Age-Related Macular Degeneration

Amy C Cohn, Zhichao Wu, Andrew I Jobling, Erica L Fletcher, Robyn H Guymer

Journal article  |  2021  |  Journal of Clinical Medicine

The presence of drusen is an important hallmark of age-related macular degeneration (AMD). Laser-induced regression of drusen, fir..

Dorsal-Ventral Differences in Retinal Structure in the Pigmented Royal College of Surgeons Model of Retinal Degeneration

Una Greferath, Mario Huynh, Andrew Ian Jobling, Kirstan Anne Vessey, Gene Venables, Denver Surrao, Helen Christine O'Neill, Ioannis J Limnios, Erica Lucy Fletcher

Journal article  |  2021  |  Frontiers in Cellular Neuroscience

Retinitis pigmentosa is a family of inherited retinal degenerations associated with gradual loss of photoreceptors, that ultimatel..

Photoreceptor Degeneration in Pro23His Transgenic Rats (Line 3) Involves Autophagic and Necroptotic Mechanisms

Kiana Kakavand, Andrew I Jobling, Ursula Greferath, Kirstan A Vessey, Robb U de Iongh, Erica L Fletcher

Journal article  |  2020  |  Frontiers in Neuroscience

Photoreceptor death contributes to 50% of irreversible vision loss in the western world. Pro23His (P23H) transgenic albino rat str..

Potential mechanisms of retinal ganglion cell type-specific vulnerability in glaucoma

Anna YM Wang, Pei Ying Lee, Bang Bui, Andrew Jobling, Ursula Greferath, Alice Brandli, Michael A Dixon, Quan Findlay, Erica L Fletcher, Kirstan A Vessey

Journal article  |  2020  |  Clinical and Experimental Optometry

Glaucoma is a neurodegenerative disease characterised by progressive damage to the retinal ganglion cells (RGCs), the output neuro..

Fractalkine-induced microglial vasoregulation occurs within the retina and is altered early in diabetic retinopathy

Samuel Mills, Andrew Jobling, Michael Dixon, Bang Bui, Kirstan Vessey, Joanna Phipps, Ursula Greferath, Gene Venables, Vickie HY Wong, Connie HY Wong, Zheng He, Flora Hui, James Young, Josh Tonc, Elena Ivanova, Botir Sagdullaev, Erica Fletcher

Journal article  |  2020

Local blood flow control within the CNS is critical to proper function and is dependent on coordination between neurons, glia and ..

Fluorescent Labeling and Quantification of Vesicular ATP Release Using Live Cell Imaging

Kirstan A Vessey, Tracy Ho, Andrew I Jobling, Anna Y Wang, Erica L Fletcher

Journal article  |  2020  |  Methods in molecular biology (Clifton, N.J.)

Adenosine triphosphate (ATP) is actively transported into vesicles for purinergic neurotransmission by the vesicular nucleotide tr..

Animal and Human Models of Retinal Diseases

Erica L Fletcher, Alice Pebay, Matt V Rutar, Kiana Kakavand, Anna Y Wang, Kirstan A Vessey, Andrew I Jobling, Ursula Greferath

Book Chapter  |  2020

Animal Models of Diseases of the Retinal Pigment Epithelium

Erica L Fletcher, Ursula Greferath, Philipp Guennel, Mario Huynh, Quan D Findlay, Andrew I Jobling, Joanna A Phipps, Alice A Brandli, Yao Mei Wang, Samuel A Mills, Kiana Kakavand, Robb U DeIongh, Kirstan A Vessey

Book Chapter  |  2020

The renin-angiotensin system and the retinal neurovascular unit: A role in vascular regulation and disease

Joanna A Phipps, Michael A Dixon, Andrew Jobling, Anna Y Wang, Ursula Greferath, Kirstan A Vessey, Erica L Fletcher

Journal article  |  2019  |  Experimental Eye Research

The retina is known to have a local renin-angiotensin system (RAS) and dysfunction in the RAS is often associated with diseases of..