Stephen Rogerson

Pathogenicity and virulence of malaria: Sticky problems and tricky solutions

Isobel S Walker, Stephen J Rogerson

Journal article  |  2023  |  VIRULENCE

Infections with Plasmodium falciparum and Plasmodium vivax cause over 600,000 deaths each year, concentrated in Africa and in youn..

Acquisition of antibodies to Plasmodium falciparum and Plasmodium vivax antigens in pregnant women living in a low malaria transmission area of Brazil

Meseret W Kassa, Wina Hasang, Andre Barateiro, Timon Damelang, Jessica Brewster, Jamille GG Dombrowski, Rhea JJ Longley, Amy W Chung, Gerhard Wunderlich, Ivo Mueller, Elizabeth H Aitken, Claudio RF Marinho, Stephen JJ Rogerson

Journal article  |  2022  |  MALARIA JOURNAL

BACKGROUND: Pregnant women have increased susceptibility to Plasmodium falciparum malaria and acquire protective antibodies over s..

Eotaxin-2 and eotaxin-3 in malaria exposure and pregnancy.

Cristina Mancebo-Pérez, Marta Vidal, Ruth Aguilar, Diana Barrios, Azucena Bardají, Maria Ome-Kaius, Clara Menéndez, Stephen J Rogerson, Carlota Dobaño, Gemma Moncunill, Pilar Requena

Journal article  |  2022  |  Malar J

BACKGROUND: Eotaxin-1 concentrations in plasma have been inversely associated with malaria exposure, malaria infection and pregnan..

Pregnancy and malaria: the perfect storm.

Stephen J Rogerson, Holger W Unger

Journal article  |  2022  |  Curr Opin Infect Dis

PURPOSE OF REVIEW: Malaria in pregnancy continues to exert a toll on pregnant women and their offspring. RECENT FINDINGS: The burd..

Relationship of circulating Plasmodium falciparum lifecycle stage to circulating parasitemia and total parasite biomass

Michael F Duffy, Gerry Q Tonkin-Hill, Leily Trianty, Rintis Noviyanti, Hanh HT Nguyen, Janavi S Rambhatla, Malcolm J McConville, Stephen J Rogerson, Graham V Brown, Ric N Price, Nicholas M Anstey, Karen P Day, Anthony T Papenfuss

Journal article  |  2022  |  NATURE COMMUNICATIONS

Induction, decay, and determinants of functional antibodies following vaccination with the RTS,S malaria vaccine in young children

Gaoqian Feng, Liriye Kurtovic, Paul A Agius, Elizabeth H Aitken, Jahit Sacarlal, Bruce D Wines, P Mark Hogarth, Stephen J Rogerson, Freya J Fowkes, Carlota Dobano, James G Beeson

Journal article  |  2022  |  BMC MEDICINE

BACKGROUND: RTS,S is the first malaria vaccine recommended for implementation among young children at risk. However, vaccine effic..

Associations of maternal iron deficiency with malaria infection in a cohort of pregnant Papua New Guinean women

Holger W Unger, Andie Bleicher, Maria Ome-Kaius, Elizabeth H Aitken, Stephen J Rogerson

Journal article  |  2022  |  MALARIA JOURNAL

BACKGROUND: Iron deficiency (ID) is common in malaria-endemic settings. Intermittent preventative treatment of malaria in pregnanc..

Tackling variants with antibodies

Elizabeth H Aitken, Stephen J Rogerson

Journal article  |  2022  |  ELIFE

Antibodies targeting the protein that causes placental malaria can recognise multiple variants of the protein, which may help guid..

Rosettes: a shield for Plasmodium falciparum against artemisinins?

Stephen J Rogerson

Journal article  |  2022  |  TRENDS IN PARASITOLOGY

Relative resistance of Plasmodium falciparum parasites to artesunate (AS) has been ascribed to mutations in the Kelch 13 gene. Lee..

Identifying Targets of Protective Antibodies against Severe Malaria in Papua, Indonesia, Using Locally Expressed Domains of Plasmodium falciparum Erythrocyte Membrane Protein 1

Janavi S Rambhatla, Gerry Q Tonkin-Hill, Eizo Takashima, Takafumi Tsuboi, Rintis Noviyanti, Leily Trianty, Boni F Sebayang, Daniel A Lampah, Jutta Marfurt, Ric N Price, Nicholas M Anstey, Anthony T Papenfuss, Timon Damelang, Amy W Chung, Michael F Duffy, Stephen J Rogerson

Journal article  |  2022  |  INFECTION AND IMMUNITY

Plasmodium falciparum erythrocyte membrane protein 1 (PfEMP1), a diverse family of multidomain proteins expressed on the surface o..