Nicholas Williamson

Patent protects post-translationally modified insulin epitopes and their use as diagnostics or therapeutics

LC Harrison, SI Mannering, A PURCELL, N WILLIAMSON

A role for Rab30 in retrograde trafficking and maintenance of endosome-TGN organization

Khalisah L Zulkefli, Ismail S Mahmoud, Nicholas A Williamson, Prajakta Kulkarni Gosavi, Fiona J Houghton, Paul A Gleeson

Journal article  |  2021  |  Experimental Cell Research

Rab30 is a poorly characterized small GTPase. Here we show that Rab30 is localised primarily to the TGN and recycling endosomes in..

What Are We Missing by Using Hydrophilic Enrichment? Improving Bacterial Glycoproteome Coverage Using Total Proteome and FAIMS Analyses

Ameera Raudah Ahmad Izaham, Ching-Seng Ang, Shuai Nie, Lauren E Bird, Nicholas A Williamson, Nichollas E Scott

Journal article  |  2021  |  Journal of Proteome Research

Hydrophilic interaction liquid chromatography (HILIC) glycopeptide enrichment is an indispensable tool for the high-throughput cha..

Quantitative lipidomic analysis of Ascaris suum

Tao Wang, Shuai Nie, Guangxu Ma, Johnny Vlaminck, Peter Geldhof, Nicholas A Williamson, Gavin E Reid, Robin B Gasser

Journal article  |  2020  |  PLOS Neglected Tropical Diseases

Ascaris is a soil-transmitted nematode that causes ascariasis, a neglected tropical disease affecting predominantly children and a..

Proteomics reveals region-specific hemostatic alterations in response to mechanical ventilation in a preterm lamb model of lung injury

Christine Schmid, Vera Ignjatovic, Boyuan Pang, Shuai Nie, Nicholas A Williamson, David G Tingay, Prue M Pereira-Fantini

Journal article  |  2020  |  Thrombosis Research

Introduction Preterm infants often require assisted ventilation, however ventilation when applied to the immature lung can initiat..

Phosphomatics: Interactive interrogation of substrate-kinase networks in global phosphoproteomics datasets.

Michael G Leeming, Sean O'Callaghan, Luana Licata, Marta Iannuccelli, Prisca Lo Surdo, Elisa Micarelli, Ching-Seng Ang, Shuai Nie, Swati Varshney, Sadia Ameen, Heung-Chin Cheng, Nicholas A Williamson

Journal article  |  2020  |  Bioinformatics

MOTIVATION: Mass spectrometry-based phosphoproteomics can routinely identify and quantify thousands of phosphorylated peptides fro..

Expanding the allergen repertoire of salmon and catfish

Thimo Ruethers, Aya C Taki, Shaymaviswanathan Karnaneedi, Shuai Nie, Tanja Kalic, Danyi Dai, Sakda Daduang, Michael Leeming, Nicholas A Williamson, Heimo Breiteneder, Sam S Mehr, Sandip D Kamath, Dianne E Campbell, Andreas L Lopata

Journal article  |  2020  |  Allergy

BACKGROUND: Diagnostic tests for fish allergy are hampered by the large number of under-investigated fish species. Four salmon all..

Collagen-An Important Fish Allergen for Improved Diagnosis

Tanja Kalic, Sandip D Kamath, Thimo Ruethers, Aya C Taki, Roni Nugraha, Thu TK Le, Piotr Humeniuk, Nicholas A Williamson, Diamond Hira, Jennifer M Rolland, Robyn E O'Hehir, Danyi Dai, Dianne E Campbell, Heimo Breiteneder, Andreas L Lopata

Journal article  |  2020  |  The Journal of Allergy and Clinical Immunology In Practice

Background Fish collagen is widely used in medicine, cosmetics, and the food industry. However, its clinical relevance as an aller..

Galectin-7 Impairs Placentation and Causes Preeclampsia Features in Mice

Ellen Menkhorst, Wei Zhou, Leilani L Santos, Sarah Delforce, Teresa So, Kate Rainczuk, Hannah Loke, Argyro Syngelaki, Swati Varshney, Nicholas Williamson, Kirsty Pringle, Morag J Young, Kypros H Nicolaides, Yves St-Pierre, Eva Dimitriadis

Journal article  |  2020  |  Hypertension

Preeclampsia is a serious pregnancy-induced disorder unique to humans. The etiology of preeclampsia is poorly understood; however,..

Discovery and characterisation of circular bacteriocin plantacyclin B21AG from Lactiplantibacillus plantarum B21.

Aida Golneshin, Mian-Chee Gor, Nicholas Williamson, Ben Vezina, Thi Thu Hao Van, Bee K May, Andrew T Smith

Journal article  |  2020  |  Heliyon

Lactiplantibacillus plantarum B21 isolated from Vietnamese sausage (nem chua) has previously displayed broad antimicrobial activit..

Lipid composition and abundance in the reproductive and alimentary tracts of female Haemonchus contortus

Tao Wang, Guangxu Ma, Shuai Nie, Nicholas A Williamson, Gavin E Reid, Robin B Gasser

Journal article  |  2020  |  Parasites and Vectors

BACKGROUND: Lipids play essential structural and functional roles in the biology of animals. Studying the composition and abundanc..