profile icon
Dr

Michael Duffy

Senior Research Fellow
Microbiology And Immunology
malaria
antigenic variation
transcription
gene expression
epigenetics
science & technology
life sciences & biomedicine
plasmodium falciparum
protozoan proteins
Michael Duffy's Profile Picture
Dr

Michael Duffy

 
Division
Medicine, Dentistry And Health Sciences
 
Primary Interest
How malaria parasites evade immunity by changing their appearance to the immune system through antigenic variation.
Michael Duffy's Profile Picture
Dr

Michael Duffy

 

Dr Michael Duffy did his PhD in Mycoplasma pneumoniae at the School of Veterinary Science at the University of Melbourne. This basic research identified a species-specific, immunodominant surface antigen that he developed into a serodiagnostic for atypical pneumonia currently produced under licence by a commercial company.

He then undertook post-doctoral research into the malaria parasite Plasmodium falciparum for the Walter and Eliza Hall Institute, but based at the Eijkman Institute in Jakarta Indonesia. He returned to University of Melbourne where his research continued into the highly variable P. falciparum proteins expressed on the infected red blood cell surface in malaria. This work contributed to the identification and characterisation of a parasite protein responsible for malaria during pregnancy. Currently he is investigating parasite proteins responsible for severe malaria that might be exploited in vaccine development. In parallel he has investigated how elements of chromatin structure regulate gene expression in P. falciparum. This work developed through his study of the epigenetic control of antigenic variation in P. falciparum and has diversified into the broader study of unique chromatin proteins in P. falciparum, including variant histones and bromodomain proteins. The latter are of particular interest as potential therapeutic targets.

Projects

Displaying the 10 most recent projects by Michael Duffy.

10

Projects

Project Types


7

Research Grant


3

Internal Research Grant


Scholarly Works

Displaying the 10 most recent scholarly works by Michael Duffy.

News

Displaying the 1 most recent news article by Michael Duffy.

Honours, Awards and Fellowships

2015

travel award $3,500

OzeMalaR

2012

travel award $7,500

OzeMalaR

2006

Early Career Researcher Award $33,864

University of Melbourne

3

Awards

Credentials

Positions

Positions


Senior Research Fellow

Microbiology And Immunology

Themis Dept Access

Medicine - Royal Melbourne Hospital

Honorary

Medicine - Royal Melbourne Hospital

Member

Australian Society for Microbiology

Member

Australian Epigenetics Alliance

Member

Australian Society for Parasitology

Member

Australian Society for Medical Research

Education

Education


Doctor of Philosophy

University of Melbourne

Bachelor of Science

University of Melbourne

Links

Links