Jonathan Crowston

Improvement in inner retinal function in glaucoma with nicotinamide (vitamin B3) supplementation: A crossover randomized clinical trial.

Flora Hui, Jessica Tang, Pete A Williams, Myra B McGuinness, Xavier Hadoux, Robert J Casson, Michael Coote, Ian A Trounce, Keith R Martin, Peter van Wijngaarden, Jonathan G Crowston

Journal article  |  2020  |  Clinical & Experimental Ophthalmology

IMPORTANCE: Retinal ganglion cells endure significant metabolic stress in glaucoma but maintain capacity to recover function. Nico..

Selective laser trabeculoplasty versus topical medication as initial glaucoma treatment: the glaucoma initial treatment study randomised clinical trial.

Ghee Soon Ang, Eva K Fenwick, Marios Constantinou, Alfred Tau Liang Gan, Ryan Eyn Kidd Man, Robert J Casson, Eric A Finkelstein, Ivan Goldberg, Paul R Healey, Konrad Pesudovs, Sutha Sanmugasundram, Jing Xie, Rachel McIntosh, Jonathan Jackson, Anthony P Wells, Andrew White, Keith Martin, Mark J Walland, Jonathan G Crowston, Ecosse Luc Lamoureux

Journal article  |  2020  |  British Journal of Ophthalmology

BACKGROUND/AIMS: To determine if selective laser trabeculoplasty (SLT) is superior to topical medication as a first-line treatment..

Effects of age on retinal macrophage responses to acute elevation of intraocular pressure

Jelena M Kezic, Vicki Chrysostomou, Paul G McMenamin, Jonathan G Crowston

Journal article  |  2020  |  Experimental Eye Research

There is accumulating evidence that aging shifts the central nervous system milieu towards a proinflammatory state, with increased..

One year structural and functional glaucoma progression after trabeculectomy.

Jacqueline Chua, Aistė Kadziauskienė, Damon Wong, Rimvydas Ašoklis, Eugenijus Lesinskas, Nguyen Duc Quang, Rachel Chong, Bingyao Tan, Michaël JA Girard, Jean Martial Mari, Jonathan G Crowston, Tin Aung, Leopold Schmetterer

Journal article  |  2020  |  Scientific Reports

We evaluated the changes in visual field mean deviation (VF MD) and retinal nerve fibre layer (RNFL) thickness in glaucoma patient..

Experimental models of glaucoma filtration surgery

RS Chong, JG Crowston, TT Wong

Journal article  |  2020  |  Acta Ophthalmologica

Utility of Self-Destructing CRISPR/Cas Constructs for Targeted Gene Editing in the Retina

Fan Li, Sandy SC Hung, Mohd Khairul Nizam Mohd Khalid, Jiang-Hui Wang, Vicki Chrysostomou, Vickie HY Wong, Vikrant Singh, Kristof Wing, Leilei Tu, James A Bender, Alice Pebay, Anna E King, Anthony L Cook, Raymond CB Wong, Bang Bui, Alex W Hewitt, Guei-Sheung Liu

Journal article  |  2019  |  Human Gene Therapy

A retinal imaging biomarker of Alzheimer's disease

Peter van Wijngaarden, Xavier Hadoux, Flora Hui, Jeremiah Lim, Christine Nguyen, Bang Bui, Jonathan Crowston

Conference Proceedings  |  2019  |  CLINICAL AND EXPERIMENTAL OPHTHALMOLOGY

Amyloid Precursor Protein Mediates Neuronal Protection from Rotenone Toxicity (vol 56, pg 5471, 2019)

Kathryn Cimdins, Hayley S Waugh, Vicki Chrysostomou, M Isabel G Lopez Sanchez, Vanessa A Johanssen, Mark J Cook, Jonathan G Crowston, Andrew F Hill, James A Duce, Ashley I Bush, Ian A Trounce

Journal article  |  2019  |  Molecular Neurobiology

Non-invasive in vivo hyperspectral imaging of the retina for potential biomarker use in Alzheimer's disease

Xavier Hadoux, Flora Hui, Jeremiah KH Lim, Colin L Masters, Alice Pebay, Sophie Chevalier, Jason Ha, Samantha Loi, Christopher J Fowler, Christopher Rowe, Victor L Villemagne, Edward N Taylor, Christopher Fluke, Jean-Paul Soucy, Frederic Lesage, Jean-Philippe Sylvestre, Pedro Rosa-Neto, Sulantha Mathotaarachchi, Serge Gauthier, Ziad S Nasreddine, et al.

Journal article  |  2019  |  NATURE COMMUNICATIONS

Amyloid Precursor Protein Mediates Neuronal Protection from Rotenone Toxicity

Kathryn Cimdins, Hayley S Waugh, Vicki Chrysostomou, M Isabel G Lopez Sanchez, Vanessa A Johannsen, Mark J Cook, Jonathan G Crowston, Andrew F Hill, James A Duce, Ashley I Bush, Ian A Trounce

Journal article  |  2019  |  MOLECULAR NEUROBIOLOGY

Transnational review of visual standards for driving: How Australia compares with the rest of the world

Mabel K Yan, Himeesh Kumar, Nathan Kerr, Felipe A Medeiros, Sukhpal S Sandhu, Jonathan Crowston, Yu XG Kong

Journal article  |  2019  |  Clinical & Experimental Ophthalmology

IMPORTANCE: Driving is a highly visual task and a primary mode of transportation for many people around the world. BACKGROUND: The..

Is the spectral effect of cataract in hyperspectral imaging random or well-defined?

Jason Ha, Xavier Hadoux, Flora Hui, Peter van Wijngaarden, Jonathan G Crowston

Conference Proceedings  |  2019  |  INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE

A Multi-Country Study of Myopia in Children: Digital Data Capture Using an Innovative Application - plano

Mohamed Dirani, Arief Salim, Stuart Keel, Jonathan G Crowston, Tien Yin Wong

Conference Proceedings  |  2019  |  INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE

Bleb-associated endophthalmitis: Proportion, presentation, management and outcomes in Victoria, Australia

Hye Jin Kwon, Himeesh Kumar, Catherine M Green, Jonathan G Crowston, Myra B McGuinness, Nathan M Kerr

Journal article  |  2019  |  Clinical & Experimental Ophthalmology

The effect of ageing on the recovery of retinal function and structure following intraocular pressure elevation in mice

Pei Ying Lee, Zheng He, Vickie Hoi Ying Wong, Jonathan G Crowston, Bang V Bui

Conference Proceedings  |  2019  |  INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE

Improving the Feasibility of Glaucoma Clinical Trials Using Trend-Based Visual Field Progression Endpoints.

Zhichao Wu, David P Crabb, Balwantray C Chauhan, Jonathan G Crowston, Felipe A Medeiros

Journal article  |  2019  |  Ophthalmology Glaucoma

Purpose: There have been concerns that short-term clinical trials for evaluating new treatments in glaucoma would require prohibit..

Prevalence of glaucoma in the Australian National Eye Health Survey

Stuart Keel, Jing Xie, Joshua Foreman, Pei Ying Lee, Mostafa Alwan, Eamonn T Fahy, Peter van Wijngaarden, Jennifer C Fan Gaskin, Ghee Soon Ang, Jonathan G Crowston, Hugh R Taylor, Mohamed Dirani

Journal article  |  2019  |  British Journal of Ophthalmology

From reading books to increased smart device screen time

Mohamed Dirani, Jonathan G Crowston, Tien Y Wong

Journal article  |  2019  |  British Journal of Ophthalmology

Visual recovery as the target for glaucoma

V Chrysostomou, RJ Hatch, T Colgan, JP Paul, P van Wijngaarden, I Trounce, MIG Lopez Sanchez, K Bell, F Grus, JG Crowston

Journal article  |  2019  |  Der Ophthalmologe

A Comparison of the RETeval Sensor Strip and DTL Electrode for Recording the Photopic Negative Response

Jessica Tang, Flora Hui, Xavier Hadoux, Marc Sarossy, Peter van Wijngaarden, Michael Coote, Jonathan G Crowston

Journal article  |  2018  |  TRANSLATIONAL VISION SCIENCE & TECHNOLOGY

Optimizing a Portable ERG Device for Glaucoma Clinic: The Effect of Interstimulus Frequency on the Photopic Negative Response

Flora Hui, Jessica Tang, Xavier Hadoux, Michael Coote, Jonathan G Crowston

Journal article  |  2018  |  TRANSLATIONAL VISION SCIENCE & TECHNOLOGY

Mitochondrial DNA Variation and Disease Susceptibility in Primary Open-Angle Glaucoma

Larry N Singh, Jonathan G Crowston, M Isabel G Lopez Sanchez, Nicole J Van Bergen, Lisa S Kearns, Alex W Hewitt, Seyhan Yazar, David A Mackey, Douglas C Wallace, Ian A Trounce

Journal article  |  2018  |  Investigative Opthalmology & Visual Science

Baseline Detrending for the Photopic Negative Response

Jessica Tang, Flora Hui, Michael Coote, Jonathan G Crowston, Xavier Hadoux

Journal article  |  2018  |  TRANSLATIONAL VISION SCIENCE & TECHNOLOGY

Physical activity, visual impairment, and eye disease

Sharon R Ong, Jonathan G Crowston, Paul D Loprinzi, Pradeep Y Ramulu

Journal article  |  2018  |  Eye

Comparison of Perimetry for Glaucoma Using Standard Size iPad and Large Screen iPad Pro with Humphrey Field Analyzer

Yu Xiang George Kong, Lukas Sahhar, Keith R Martin, Mingguang He, Jonathan G Crowston, Algis J Vingrys

Conference Proceedings  |  2018  |  INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE

An optimised protocol for the portable electroretinogram device to probe changes in glaucoma

Jessica Tang, Flora Hui, Xavier Hadoux, Bernardo Soares, Michael Jamieson, Jonathan G Crowston

Conference Proceedings  |  2018  |  INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE

Pointwise variability of a tablet perimetry application

Algis J Vingrys, Selwyn M Prea, Aditi Mehta, Mingguang He, Jonathan G Crowston, Viney Gupta, Keith R Martin, Yu Xiang George Kong

Conference Proceedings  |  2018  |  INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE

Interrogating new targets for glaucoma gene therapy

Timothy D Colgan, Vicki Chrysostomou, Joseph Paul, Sze Ng, Elsa Chan, Peter van Wijngaarden, Jonathan G Crowston

Conference Proceedings  |  2018  |  INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE

Protection of the injured optic nerve with forced and voluntary exercise in aged mice: can there be too much of a good thing?

Vicki Chrysostomou, Peter van Wijngaarden, Joseph Paul, Timothy Colgan, Ian A Trounce, Jonathan G Crowston

Conference Proceedings  |  2018  |  INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE

Intra-optic nerve delivery of AAV-mediated gene therapy in mice

Joseph Paul, Timothy Colgan, Vicki Chrysostomou, Peter van Wijngaarden, Jonathan G Crowston

Conference Proceedings  |  2018  |  INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE

The coma in glaucoma: Retinal ganglion cell dysfunction and recovery

Lewis E Fry, Eamonn Fahy, Vicki Chrysostomou, Flora Hui, Jessica Tang, Peter van Wijngaarden, Steven Petrou, Jonathan G Crowston

Journal article  |  2018  |  Progress in Retinal and Eye Research

The effect of inter-stimulus frequency on the photopic negative response in glaucoma and healthy eyes

Flora Hui, Jessica Tang, Xavier Hadoux, Jonathan G Crowston

Conference Proceedings  |  2018  |  INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE

Six-month Longitudinal Comparison of a Portable Tablet Perimeter With the Humphrey Field Analyzer

Selwyn Marc Prea, Yu Xiang George Kong, Aditi Mehta, Mingguang He, Jonathan G Crowston, Vinay Gupta, Keith R Martin, Algis J Vingrys

Journal article  |  2018  |  American Journal of Ophthalmology

Prevalence and Causes of Visual Loss Among the Indigenous Peoples of the World A Systematic Review

Joshua Foreman, Stuart Keel, Peter van Wijngaarden, Rupert A Bourne, Richard Wormald, Jonathan Crowston, Hugh R Taylor, Mohamed Dirani

Journal article  |  2018  |  JAMA Ophthalmology

Prevalence and Causes of Unilateral Vision Impairment and Unilateral Blindness in Australia The National Eye Health Survey

Joshua Foreman, Jing Xie, Stuart Keel, Ghee Soon Ang, Pei Ying Lee, Rupert Bourne, Jonathan G Crowston, Hugh R Taylor, Mohamed Dirani

Journal article  |  2018  |  JAMA Ophthalmology

Vision loss in Indigenous peoples of the world: a systematic review protocol.

Joshua Foreman, Stuart Keel, Peter van Wijngaarden, Rupert Bourne, Richard Wormald, Jonathan Crowston, Hugh R Taylor, Mohamed Dirani

Journal article  |  2018  |  JBI Database of Systematic Reviews and Implementation Reports

REVIEW OBJECTIVE/QUESTION: The objectives of this review are.

Optic Nerve Head Drusen: An Update

Edward Palmer, Jesse Gale, Jonathan G Crowston, Anthony P Wells

Journal article  |  2018  |  Neuro-Ophthalmology

Objective Assessment of Activity Limitation in Glaucoma with Smartphone Virtual Reality Goggles: A Pilot Study.

Rachel LZ Goh, Yu Xiang George Kong, Colm McAlinden, John Liu, Jonathan G Crowston, Simon E Skalicky

Journal article  |  2018  |  Translational vision science & technology

Purpose: To evaluate the use of smartphone-based virtual reality to objectively assess activity limitation in glaucoma. Methods: C..

The Prevalence and Causes of Vision Loss in Indigenous and Non-Indigenous Australians

Joshua Foreman, Jing Xie, Stuart Keel, Peter van Wijngaarden, Sukhpal Singh Sandhu, Ghee Soon, Jennifer Fan Gaskin, Jonathan Crowston, Rupert Bourne, Hugh R Taylor, Mohamed Dirani

Journal article  |  2017  |  Ophthalmology

COMPARISON OF PERIMETRY FOR GLAUCOMA USING STANDARD-SIZED IPAD AND LARGE SCREEN IPAD PRO WITH HUMPHREY FIELD ANALYZER

Lukas Sahhar, Keith Martin, Jonathan Crowston, Algis Vingrys, George Kong

Conference Proceedings  |  2017  |  CLINICAL AND EXPERIMENTAL OPHTHALMOLOGY

MULTICENTER LONGITUDINAL COMPARISON OF PERIMETRY RESULTS BETWEEN IPAD PERIMETER AND HUMPHREY FIELD ANALYZER FOR GLAUCOMA

Yu Xiang George Kong, Selwyn Marc Prea, Aditi Mehta, Mingguang He, Jonathan Crowston, Viney Gupta, Keith Martin, Algis Vingrys

Conference Proceedings  |  2017  |  CLINICAL AND EXPERIMENTAL OPHTHALMOLOGY

Cataract surgery coverage rates for Indigenous and non-Indigenous Australians: the National Eye Health Survey

Joshua Foreman, Jing Xie, Stuart Keel, Peter van Wijngaarden, Jonathan Crowston, Hugh R Taylor, Mohamed Dirani

Journal article  |  2017  |  Medical Journal of Australia

A short term high-fat high-sucrose diet in mice impairs optic nerve recovery after injury and this is not reversed by exercise

Vicki Chrysostomou, Peter van Wijngaarden, Gregory R Steinberg, Jonathan G Crowston

Journal article  |  2017  |  Experimental Eye Research

Impact of Normal Aging and Progression Definitions on the Specificity of Detecting Retinal Nerve Fiber Layer Thinning

Zhichao Wu, Luke J Saunders, Linda M Zangwill, Fabio B Daga, Jonathan G Crowston, Felipe A Medeiros

Journal article  |  2017  |  American Journal of Ophthalmology

Amyloid precursor protein drives down-regulation of mitochondrial oxidative phosphorylation independent of amyloid beta

M Isabel G Lopez Sanchez, Hayley S Waugh, Andrew Tsatsanis, Bruce X Wong, Jonathan G Crowston, James A Duce, Ian A Trounce

Journal article  |  2017  |  SCIENTIFIC REPORTS

Genetic association study of exfoliation syndrome identifies a protective rare variant at LOXL1 and five new susceptibility loci

Tin Aung, Mineo Ozaki, Mei Chin Lee, Ursula Schlotzer-Schrehardt, Gudmar Thorleifsson, Takanori Mizoguchi, Robert P Igo, Aravind Haripriya, Susan E Williams, Yury S Astakhov, Andrew C Orr, Kathryn P Burdon, Satoko Nakano, Kazuhiko Mori, Khaled Abu-Amero, Michael Hauser, Zheng Li, Gopalakrishnan Prakadeeswari, Jessica N Cooke Bailey, Alina Popa Cherecheanu, et al.

Journal article  |  2017  |  Nature Genetics

Surgical outcomes of trabeculectomy and glaucoma drainage implant for uveitic glaucoma and relationship with uveitis activity

Hye Jin Kwon, Yu Xiang George Kong, Lingwei William Tao, Lyndell L Lim, Keith R Martin, Catherine Green, Jonathan Ruddle, Jonathan G Crowston

Journal article  |  2017  |  CLINICAL AND EXPERIMENTAL OPHTHALMOLOGY

The Impact of Normal Aging and Definitions of Progression on Detecting Retinal Nerve Fiber Layer Changes in Optical Coherence Tomography Imaging

Luke J Saunders, Zhichao Wu, Linda M Zangwill, Fabio Bernardi Daga, Jonathan Crowston, Robert N Weinreb, Felipe Medeiros

Conference Proceedings  |  2017  |  INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE

Improving the Feasibility of Glaucoma Clinical Trials With Trend-Based Analysis of Visual Field Change Between Groups as an Endpoint

Zhichao Wu, Balwantray C Chauhan, David Garway-Heath, David Paul Crabb, Jonathan Crowston, Felipe Medeiros

Conference Proceedings  |  2017  |  INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE

Transforming Growth Factor beta 1-Induced NADPH Oxidase-4 Expression and Fibrotic Response in Conjunctival Fibroblasts

Karl David Brown, Manisha H Shah, Guei-Sheung Liu, Elsa C Chan, Jonathan G Crowston, Hitesh M Peshavariya

Journal article  |  2017  |  INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE

Longitudinal comparison of visual field outcomes obtained by a tablet perimeter and those returned by Humphrey Field Analyzer

Yu Xiang George Kong, Mingguang He, Jonathan Crowston, Keith R Martin, Algis J Vingrys

Conference Proceedings  |  2017  |  INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE

Relief for retinal neurons under pressure

Jonathan Crowston, Ian Trounce

Journal article  |  2017  |  Science

Targeting retinal ganglion cell recovery

JG Crowston, ET Fahy, L Fry, IA Trounce, P van Wijngaarden, S Petrou, V Chrysostomou

Journal article  |  2017  |  Eye

Glaucoma laser and surgical procedure rates in Australia

Nathan M Kerr, Himeesh K Kumar, Jonathan G Crowston, Mark J Walland

Journal article  |  2016  |  British Journal of Ophthalmology

Exercise reverses age-related vulnerability of the retina to injury by preventing complement-mediated synapse elimination via a BDNF-dependent pathway

Vicki Chrysostomou, Sandra Galic, Peter van Wijngaarden, Ian A Trounce, Gregory R Steinberg, Jonathan G Crowston

Journal article  |  2016  |  Aging Cell

A Comparison of Perimetric Results from a Tablet Perimeter and Humphrey Field Analyzer in Glaucoma Patients

Yu Xiang George Kong, Mingguang He, Jonathan G Crowston, Algis J Vingrys

Journal article  |  2016  |  TRANSLATIONAL VISION SCIENCE & TECHNOLOGY

Primary open-angle glaucoma

Robert N Weinreb, Christopher KS Leung, Jonathan G Crowston, Felipe A Medeiros, David S Friedman, Janey L Wiggs, Keith R Martin

Journal article  |  2016  |  Nature Reviews Disease Primers

Porosity of Bleb Capsule declines rapidly with Fluid Challenge.

Surinder S Pandav, Craig M Ross, Faisal Thattaruthody, Ritambhra Nada, Nirbhai Singh, Natasha Gautam, Stephen Beirne, Gordon G Wallace, Mark B Sherwood, Jonathan G Crowston, Michael Coote

Journal article  |  2016  |  Journal of Current Glaucoma Practice

INTRODUCTION: The porosity of the fibrous capsule around a glaucoma drainage device (GDD) may be the most important functional att..

Emerging Mitochondrial Therapeutic Targets in Optic Neuropathies

MIG Lopez Sanchez, JG Crowston, DA Mackey, IA Trounce

Journal article  |  2016  |  Pharmacology & Therapeutics

Test-Retest Variability of Fundus-Tracked Perimetry at the Peripapillary Region in Open Angle Glaucoma

Zhichao Wu, Allison M McKendrick, Xavier Hadoux, Jennifer C Fan Gaskin, Ghee Soon Ang, Marc G Sarossy, Jonathan G Crowston

Journal article  |  2016  |  INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE

Photopic Negative Response Obtained Using a Handheld Electroretinogram Device: Determining the Optimal Measure and Repeatability

Zhichao Wu, Xavier Hadoux, Flora Hui, Marc G Sarossy, Jonathan G Crowston

Journal article  |  2016  |  TRANSLATIONAL VISION SCIENCE & TECHNOLOGY

Impact of age-related macular degeneration in patients with glaucoma: understanding the patients' perspective

Simon E Skalicky, Eva Fenwick, Keith R Martin, Jonathan Crowston, Ivan Goldberg, Peter McCluskey

Journal article  |  2016  |  Clinical & Experimental Ophthalmology

AAV-Mediated CRISPR/Cas Gene Editing of Retinal Cells In Vivo

Sandy SC Hung, Vicki Chrysostomou, Fan Li, Jeremiah KH Lim, Jiang-Hui Wang, Joseph E Powell, Leilei Tu, Maciej Daniszewski, Camden Lo, Raymond C Wong, Jonathan G Crowston, Alice Pebay, Anna E King, Bang V Bui, Guei-Sheung Liu, Alex W Hewitt

Journal article  |  2016  |  Investigative Opthalmology & Visual Science

Axonal transport along retinal ganglion cells is grossly intact during reduced function post-injury

ET Fahy, V Chrysostomou, CJ Abbott, P van Wijngaarden, JG Crowston

Journal article  |  2016  |  Experimental Eye Research

Measuring the Photopic Negative Response: Viability of Skin Electrodes and Variability Across Disease Severities in Glaucoma

Zhichao Wu, Xavier Hadoux, Jennifer C Fan Gaskin, Marc G Sarossy, Jonathan G Crowston

Journal article  |  2016  |  Translational Vision Science & Technology

Glaucoma neurorecovery - a sugar-coated road to retinal ganglion cell recovery

Jonathan G Crowston, Peter van Wijngaarden

Journal article  |  2016  |  Clinical & Experimental Ophthalmology

Mini-Review: Impaired Axonal Transport and Glaucoma

Eamonn T Fahy, Vicki Chrysostomou, Jonathan G Crowston

Journal article  |  2016  |  Current Eye Research

An acute intraocular pressure challenge to assess retinal ganglion cell injury and recovery in the mouse

Jonathan G Crowston, Yu Xiang G Kong, Ian A Trounce, Trung M Dang, Eamonn T Fahy, Bang V Bui, John C Morrison, Vicki Chrysostomou

Journal article  |  2015  |  Experimental Eye Research

Measurement of Systemic Mitochondrial Function in Advanced Primary Open-Angle Glaucoma and Leber Hereditary Optic Neuropathy

Nicole J Van Bergen, Jonathan G Crowston, Jamie E Craig, Kathryn P Burdon, Lisa S Kearns, Shiwani Sharma, Alex W Hewitt, David A Mackey, Ian A Trounce

Journal article  |  2015  |  PLOS ONE

Effects of ranibizumab on TGF-beta 1 and TGF-beta 2 production by human Tenon's fibroblasts: An in vitro study

Siti Munirah Md Noh, Siti H Sheikh Abdul Kadir, Jonathan G Crowston, Visvaraja Subrayan, Sushil Vasudevan

Journal article  |  2015  |  Molecular Vision

Comparing the effectiveness of selective laser trabeculoplasty with topical medication as initial treatment (the Glaucoma Initial Treatment Study): study protocol for a randomised controlled trial

Ecosse L Lamoureux, Rachel Mcintosh, Marios Constantinou, Eva K Fenwick, Jing Xie, Robert Casson, Eric Finkelstein, Ivan Goldberg, Paul Healey, Ravi Thomas, Ghee Soon Ang, Konrad Pesudovs, Jonathan Crowston

Journal article  |  2015  |  Trials

Metformin can alleviate the age-related retinal vulnerability to pressure injury by reducing oxidative stress level

F Rezania, V Chrysostomou, J Crowston

Conference Proceedings  |  2015  |  JOURNAL OF NEUROCHEMISTRY

The Eye Phone Study: reliability and accuracy of assessing Snellen visual acuity using smartphone technology

C Perera, R Chakrabarti, FMA Islam, J Crowston

Journal article  |  2015  |  EYE

Determination of Bleb Capsule Porosity With an Experimental Glaucoma Drainage Device and Measurement System

Craig Ross, Surinder Singh Pandav, Yu Qin Li, Dan Q Nguyen, Stephen Beirne, Gordon G Wallace, Tarek Shaarawy, Jonathan G Crowston, Michael Coote

Journal article  |  2015  |  JAMA Ophthalmology

Cataract and quality of life in patients with glaucoma

Simon E Skalicky, Keith R Martin, Eva Fenwick, Jonathan G Crowston, Ivan Goldberg, Peter McCluskey

Journal article  |  2015  |  Clinical & Experimental Ophthalmology

A common variant mapping to CACNA1A is associated with susceptibility to exfoliation syndrome

Tin Aung, Mineo Ozaki, Takanori Mizoguchi, R Rand Allingham, Zheng Li, Aravind Haripriya, Satoko Nakano, Steffen Uebe, Jeffrey M Harder, Anita SY Chan, Mei Chin Lee, Kathryn P Burdon, Yury S Astakhov, Khaled K Abu-Amero, Juan C Zenteno, Yildirim Nilguen, Tomasz Zarnowski, Mohammad Pakravan, Leen Abu Safieh, Liyun Jia, et al.

Journal article  |  2015  |  Nature Genetics

Clinical audit examining the impact of benzalkonium chloride-free anti-glaucoma medications on patients with symptoms of ocular surface disease

Ivan Goldberg, Stuart L Graham, Jonathan G Crowston, Guy d'Mellow

Journal article  |  2015  |  Clinical & Experimental Ophthalmology

Erratum: A common variant mapping to CACNA1A is associated with susceptibility to exfoliation syndrome (Nature Genetics (2015) 47 (387-392))

T Aung, M Ozaki, T Mizoguchi, RR Allingham, Z Li, A Haripriya, S Nakano, S Uebe, JM Harder, ASY Chan, MC Lee, KP Burdon, YS Astakhov, KK Abu-Amero, JC Zenteno, Y Nilgün, T Zarnowski, M Pakravan, LA Safieh, L Jia, et al.

Journal article  |  2015  |  Nature Genetics

Tenon's Cyst Formation, Wound Healing, and Bleb Evaluation

A Wells, TT Wong, JG Crowston

Book Chapter  |  2015

Role of adenosine receptors in resveratrol-induced intraocular pressure lowering in rats with steroid-induced ocular hypertension

Norhafiza Razali, Renu Agarwal, Puneet Agarwal, Sunil Kumar, Minaketan Tripathy, Sushil Vasudevan, Jonathan G Crowston, Nafeeza M Ismail

Journal article  |  2015  |  Clinical & Experimental Ophthalmology

Preface

TM Shaarawy, MB Sherwood, RA Hitchings, JG Crowston

Book  |  2015

IMPACT OF AGE-RELATED MACULAR DEGENERATION ON QUALITY OF LIFE IN PATIENTS WITH GLAUCOMA

Simon Skalicky, Keith Martin, Jonathan Crowston, Eva Fenwick, Ivan Goldberg, Peter McCluskey

Conference Proceedings  |  2014  |  CLINICAL AND EXPERIMENTAL OPHTHALMOLOGY

The Test-Retest Reliability of the Photopic Negative Response (PhNR)

Jessica Tang, Thomas Edwards, Jonathan G Crowston, Marc Sarossy

Journal article  |  2014  |  Translational Vision Science & Technology

Effects of ranibizumab on the extracellular matrix production by human Tenon's fibroblast

Siti Munirah Md Noh, Siti H Sheikh Abdul Kadir, Zakaria M Bannur, Gabriele Anisah Froemming, Narimah Abdul Hamid Hasani, Hapizah Mohd Nawawi, Jonathan G Crowston, Sushi Vasudevan

Journal article  |  2014  |  Experimental Eye Research

Glaucoma: Second Edition

TM Shaarawy, MB Sherwood, RA Hitchings, JG Crowston

Book  |  2014

Physical inactivity as a risk factor for diabetic retinopathy? A review

Mohamed Dirani, Jonathan G Crowston, Peter van Wijngaarden

Journal article  |  2014  |  Clinical and Experimental Ophthalmology

Interferon-alpha and interferon-gamma modulate Fas-mediated apoptosis in mitomycin-C-resistant human Tenon's fibroblasts

Xiao Yang Wang, Jonathan G Crowston, Andrew JR White, Hans Zoellner, Paul R Healey

Journal article  |  2014  |  Clinical & Experimental Ophthalmology

Effect of phacoemulsification on trabeculectomy function

Dan Q Nguyen, Nuwan Niyadurupola, Robyn J Tapp, Rachael A O'Connell, Michael A Coote, Jonathan G Crowston

Journal article  |  2014  |  Clinical & Experimental Ophthalmology

Forced exercise protects the aged optic nerve against intraocular pressure injury

Vicki Chrysostomou, Jelena M Kezic, Ian A Trounce, Jonathan G Crowston

Journal article  |  2014  |  Neurobiology of Aging

Rise of intraocular pressure in a caffeine test versus the water drinking test in patients with glaucoma

Tran Tuan, Nuwan Niyadurupola, Jeremy O'Connor, Ghee Soon Ang, Jonathan Crowston, Nguyen Dan

Journal article  |  2014  |  Clinical & Experimental Ophthalmology

Beliefs and Adherence to Glaucoma Treatment: A Comparison of Patients From Diverse Cultures

Gwyneth Rees, Xue-Ling Chong, Carol Y Cheung, Tin Aung, David S Friedman, Jonathan G Crowston, Ecosse L Lamoureux

Journal article  |  2014  |  Journal of Glaucoma

Glaucomatous Optic Neuropathy Evaluation Project Factors Associated With Underestimation of Glaucoma Likelihood

Evelyn C O'Neill, Lulu U Gurria, Surinder S Pandav, Yu Xiang G Kong, Jessica F Brennan, Jing Xie, Michael A Coote, Jonathan G Crowston

Journal article  |  2014  |  JAMA Ophthalmology

Wound Healing Modulation in Glaucoma Filtration Surgery-Conventional Practices and New Perspectives: The Role of Antifibrotic Agents (Part I).

Jennifer C Fan Gaskin, Dan Q Nguyen, Ghee Soon Ang, Jeremy O'Connor, Jonathan G Crowston

Journal article  |  2014  |  Journal of Current Glaucoma Practice

Glaucoma filtration surgery is regularly performed for the treatment of glaucoma and trabeculectomy is often regarded as the 'gold..

Glaucomatous Optic Neuropathy Evaluation (GONE) Project: The Effect of Monoscopic Versus Stereoscopic Viewing Conditions on Optic Nerve Evaluation

Helen HL Chan, Dai Ni Ong, Yu Xiang G Kong, Evelyn C O'Neill, Surinder S Pandav, Michael A Coote, Jonathan G Crowston

Journal article  |  2014  |  American Journal of Ophthalmology

Wound Healing Modulation in Glaucoma Filtration Surgery- Conventional Practices and New Perspectives: Antivascular Endothelial Growth Factor and Novel Agents (Part II).

Jennifer C Fan Gaskin, Dan Q Nguyen, Ghee Soon Ang, Jeremy O'Connor, Jonathan G Crowston

Journal article  |  2014  |  Journal of Current Glaucoma Practice

Glaucoma filtration surgery is regularly performed for the treatment of glaucoma and trabeculectomy is often regarded as the 'gold..

Validation of rebound tonometry for intraocular pressure measurement in the rabbit

Hong Zhang, Dong Yang, Craig M Ross, Jonathan P Wigg, Surinder Pandav, Jonathan G Crowston

Journal article  |  2014  |  Experimental Eye Research

Ultrasound-mediated transscleral delivery of Avastin to the posterior segment of rabbit eye in vivo

Hong Zhang, Dong Yang, Jonathan P Wigg, Harry Unger, Mark Unger, Jonathan G Crowston

Conference Proceedings  |  2014  |  INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE

Amyloid precursor protein protects against a rodent model of optic neuropathy and is abundant in the human vitreous

Hayley Waugh, Vicki Chrysostomou, Jonathan G Crowston, Ian Trounce

Conference Proceedings  |  2014  |  INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE

Axonal transport following acute intraocular pressure elevation in mice

Eamonn T Fahy, Vicki Chrysostomou, Carla J Abbott, Jonathan G Crowston

Conference Proceedings  |  2014  |  INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE

Mitochondrial Impairments in Primary Open Angle Glaucoma Patient Lymphoblasts

Nicole J Van Bergen, Jamie E Craig, Alex W Hewitt, Kathryn P Burdon, Shiwani Sharma, Jonathan G Crowston, Ian V Trounce

Conference Proceedings  |  2014  |  INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE

Publication output of senior academic ophthalmologists in Australia and New Zealand

David A Mackey, Jonathan G Crowston, Charles NJ McGhee, Peter McCluskey

Journal article  |  2014  |  Clinical and Experimental Ophthalmology

Oxidative phosphorylation measurement in cell lines and tissues

Nicole J Van Bergen, Rachel E Blake, Jonathan G Crowston, Ian A Trounce

Journal article  |  2014  |  Mitochondrion

EXERCISE PROTECTS THE AGED RETINA AGAINST INJURY

Vicki Chrysostomou, Jelena M Kezic, Ian A Trounce, Jonathan G Crowston

Conference Proceedings  |  2013  |  CLINICAL AND EXPERIMENTAL OPHTHALMOLOGY

MITOCHONDRIAL IMPAIRMENT AND VULNERABILITY OF THE OPTIC NERVE TO INJURY

Ian A Trounce, Nicole Van Bergen, Vicki Chrysostomou, Rachel Blake, Jonathan Crowston

Conference Proceedings  |  2013  |  CLINICAL AND EXPERIMENTAL OPHTHALMOLOGY

Incidence and predictors of glaucoma following surgery for congenital cataract in the first year of life in Victoria, Australia

Jonathan B Ruddle, Sandra E Staffieri, Jonathan G Crowston, Justin C Sherwin, David A Mackey

Journal article  |  2013  |  Clinical and Experimental Ophthalmology

P-glycoprotein Blockers Augment the Effect of Mitomycin C on Human Tenon's Fibroblasts

Andrew JR White, Elizabeth Kelly, Paul R Healey, Jonathan G Crowston, Paul Mitchell, Hans Zoellner

Journal article  |  2013  |  Translational Vision Science & Technology

Advancing age and mitochondrial dysfunction impair optic nerve recovery after IOP challenge

JG Crowston

Journal article  |  2013  |  Acta Ophthalmologica

The Photopic Negative Response of the Mouse Electroretinogram: Reduction by Acute Elevation of Intraocular Pressure

Vicki Chrysostomou, Jonathan G Crowston

Journal article  |  2013  |  Investigative Ophthalmology and Visual Science

A model to measure surgical outflow using a two-tubed experimental glaucoma drainage device.

Craig Ross, Dan Nguyen, Surinder Pandav, Yu Qin Li, Jonathan Crowston, Michael Coote

Conference Proceedings  |  2013  |  INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE

Effect of Anterior Chamber Cannulation and Acute IOP Elevation on Retinal Macrophages in the Adult Mouse

Jelena M Kezic, Vicki Chrysostomou, Ian A Trounce, Paul G McMenamin, Jonathan G Crowston

Journal article  |  2013  |  Investigative Ophthalmology and Visual Science

Intraocular Pressure Lowering Is Associated with an Increase in the Photopic Negative Response (PhNR) Amplitude in Glaucoma and Ocular Hypertensive Eyes

Nuwan Niyadurupola, Chi D Luu, Dan Q Nguyen, Kristen Geddes, Gary XV Tan, Celestine CW Wong, Tu Tran, Michael A Coote, Jonathan G Crowston

Journal article  |  2013  |  Investigative Ophthalmology and Visual Science

Burden of Ocular Surface Disease in Patients With Glaucoma From Australia.

Colin CK Chan, Jonathan G Crowston, Robert Tan, Mihaela Marin, Sharon Charles

Journal article  |  2013  |  Asia-Pacific Journal of Ophthalmology

PURPOSE: In the Australian general population, the economic burden of ocular surface disease (OSD) severity and other dry eye-rela..

Oxidative stress and mitochondrial dysfunction in glaucoma

Vicki Chrysostomou, Fatemeh Rezania, Ian A Trounce, Jonathan G Crowston

Journal article  |  2013  |  Current Opinion in Pharmacology

Molecular biomarkers in glaucoma.

Sanjoy K Bhattacharya, Richard K Lee, Franz H Grus, undefined Seventh ARVO/Pfizer Ophthalmics Research Institute Conference Working Group

Journal article  |  2013  |  Investigative Ophthalmology and Visual Science

Sociodemographic factors and utilization of eye care services: is there an association with patients presenting to a tertiary referral hospital in acute angle-closure?

Suneet Sandhu, Peter Van Wijngaarden, Dan Q Nguyen, Fleur O'Hare, Navneet Sandhu, Jie Jin Wang, Jonathan G Crowston

Journal article  |  2013  |  Clinical and Experimental Ophthalmology

Is primary open-angle glaucoma part of a generalized sensory neurodegeneration? A review of the evidence

Fleur O'Hare, Gary Rance, Allison M McKendrick, Jonathan G Crowston

Journal article  |  2012  |  Clinical and Experimental Ophthalmology

THE EYE PHONE STUDY (EPS): RELIABILITY AND ACCURACY OF ASSESSING SNELLEN VISUAL ACUITY USING SMART-PHONE TECHNOLOGY

Chandrashan Perera, Rahul Chakrabarti, Amirul Islam, Jonathon Crowston

Journal article  |  2012  |  Eye

Bleb vascularity following post-trabeculectomy subconjunctival bevacizumab: a pilot study

Brian E Chua, Dan Q Nguyen, Queena Qin, Jonathan B Ruddle, Anthony P Wells, Nuwan Niyadurupola, Viney Gupta, Tina T Wong, Michael A Coote, Jonathan G Crowston

Journal article  |  2012  |  Clinical and Experimental Ophthalmology

A Model to Measure Fluid Outflow in Rabbit Capsules Post Glaucoma Implant Surgery

Dan Q Nguyen, Craig M Ross, Yu Qin Li, Surinder Pandav, Bruce Gardiner, David Smith, Alicia C How, Jonathan G Crowston, Michael A Coote

Journal article  |  2012  |  Investigative Ophthalmology and Visual Science

Prevalence of signs and symptoms of ocular surface disease in individuals treated and not treated with glaucoma medication

Sudipta Ghosh, Fleur O'Hare, Ecosse Lamoureux, Rasik B Vajpayee, Jonathan G Crowston

Journal article  |  2012  |  Clinical and Experimental Ophthalmology

Auditory and Visual Temporal Processing Disruption in Open Angle Glaucoma

Fleur O'Hare, Gary Rance, Jonathan G Crowston, Allison M McKendrick

Journal article  |  2012  |  Investigative Ophthalmology and Visual Science

Impact of aging and diet restriction on retinal function during and after acute intraocular pressure injury

Yu Xiang George Kong, Nicole van Bergen, Bang V Bui, Vicki Chrysostomou, Algis J Vingrys, Ian A Trounce, Jonathan G Crowston

Journal article  |  2012  |  Neurobiology of Aging

Definition of glaucoma: clinical and experimental concepts

Robert J Casson, Glyn Chidlow, John PM Wood, Jonathan G Crowston, Ivan Goldberg

Journal article  |  2012  |  Clinical and Experimental Ophthalmology

Translational neuroprotection research in glaucoma: a review of definitions and principles

Robert J Casson, Glyn Chidlow, Andreas Ebneter, John PM Wood, Jonathan Crowston, Ivan Goldberg

Journal article  |  2012  |  Clinical and Experimental Ophthalmology

Impaired Complex-I-Linked Respiration and ATP Synthesis in Primary Open-Angle Glaucoma Patient Lymphoblasts

Shanjean Lee, Leo Sheck, Jonathan G Crowston, Nicole J Van Bergen, Evelyn C O'Neill, Fleur O'Hare, Yu Xiang George Kong, Vicki Chrysostomou, Andrea L Vincent, Ian A Trounce

Journal article  |  2012  |  Investigative Ophthalmology and Visual Science

Comment on 'Phakic intraocular lenses outcomes and complications: Artisan vs Visian ICL'

DQ Nguyen, TY Toh, JB Ruddle, JG Crowston, MC Coote

Journal article  |  2012  |  Eye

Bilateral acute severe intraocular pressure elevation requiring filtration surgery after implantation of toric Artisan phakic intraocular lenses

Tze'Yo Toh, Dan Q Nguyen, Jonathan B Ruddle, Jonathan G Crowston, Michael A Coote

Journal article  |  2012  |  Clinical and Experimental Ophthalmology

Revision trabeculectomy: Pearls and pitfalls

M Coote, J Crowston

Journal article  |  2012  |  Journal of Current Glaucoma Practice

Auditory processing deficits in individuals with primary open-angle glaucoma

Gary Rance, Fleur O'Hare, Stephen O'Leary, Arnold Starr, Anna Ly, Belinda Cheng, Dani Tomlin, Kelley Graydon, Donella Chisari, Ian Trounce, Jonathan Crowston

Journal article  |  2012  |  International Journal of Audiology

Intraocular Pressure-lowering Efficacy of Brinzolamide When Added to Travoprost/Timolol Fixed Combination as Adjunctive Therapy

Ivan Goldberg, Jonathan G Crowston, Mark C Jasek, Jeanette A Stewart, William C Stewart

Journal article  |  2012  |  Journal of Glaucoma

Is primary open-angle glaucoma part of a generalized sensory neurodegeneration? A review of the evidence

F O'Hare, G Rance, AM Mckendrick, JG Crowston

Journal article  |  2012  |  Clinical and Experimental Ophthalmology

Economic impact of primary open-angle glaucoma in Australia

Mohamed Dirani, Jonathan G Crowston, Penny S Taylor, Peter T Moore, Sophie Rogers, M Lynne Pezzullo, Jill E Keeffe, Hugh R Taylor

Journal article  |  2011  |  Clinical and Experimental Ophthalmology

Posterior Revision for Failed Blebs: Long-term Outcomes

Michael A Coote, Viney Gupta, Sushil Vasudevan, Jonathan G Crowston

Journal article  |  2011  |  Journal of Glaucoma

Increase in mitochondrial DNA mutations impairs retinal function and renders the retina vulnerable to injury

Yu XG Kong, Nicole Van Bergen, Ian A Trounce, Bang V Bui, Vicki Chrysostomou, Hayley Waugh, Algis Vingrys, Jonathan G Crowston

Journal article  |  2011  |  AGING CELL

Mitochondrial dysfunction in glaucoma and emerging bioenergetic therapies

Shanjean Lee, Nicole J Van Bergen, George Y Kong, Vicki Chrysostomou, Hayley S Waugh, Evelyn C O'Neill, Jonathan G Crowston, Ian A Trounce

Journal article  |  2011  |  Experimental Eye Research

Preservation of myelinated nerve fibres in advanced glaucoma

Tze'Yo Toh, Jonathan B Ruddle, Michael A Coote, Jonathan G Crowston

Journal article  |  2011  |  Clinical and Experimental Ophthalmology

Mitochondrial Oxidative Phosphorylation Compensation May Preserve Vision in Patients with OPA1-Linked Autosomal Dominant Optic Atrophy

Nicole J Van Bergen, Jonathan G Crowston, Lisa S Kearns, Sandra E Staffieri, Alex W Hewitt, Amy C Cohn, David A Mackey, Ian A Trounce

Journal article  |  2011  |  PLoS One

Gaze Behavior among Experts and Trainees during Optic Disc Examination: Does How We Look Affect What We See?

Evelyn C O'Neill, Yu Xiang George Kong, Paul P Connell, Dai Ni Ong, Sharon A Haymes, Michael A Coote, Jonathan G Crowston

Journal article  |  2011  |  Investigative Ophthalmology and Visual Science

Validation of the Glaucoma Filtration Surgical Mouse Model for Antifibrotic Drug Evaluation

Li-Fong Seet, Wing Sum Lee, Roseline Su, Sharon N Finger, Jonathan G Crowston, Tina T Wong

Journal article  |  2011  |  Molecular Medicine

Glaucomatous optic neuropathy evaluation project: a standardized internet system for assessing skills in optic disc examination

Yu Xiang G Kong, Michael A Coote, Evelyn C O'Neill, Lulu U Gurria, Jing Xie, David Garway-Heath, Felipe A Medeiros, Jonathan G Crowston

Journal article  |  2011  |  Clinical and Experimental Ophthalmology

Optic Disc Evaluation in Optic Neuropathies The Optic Disc Assessment Project

Evelyn C O'Neill, Helen V Danesh-Meyer, George XY Kong, Alex W Hewitt, Michael A Coote, David A Mackey, Jonathan G Crowston

Journal article  |  2011  |  Ophthalmology

Vascular risk factors in glaucoma: a review

Masahide Yanagi, Ryo Kawasaki, Jie Jin Wang, Tien Y Wong, Jonathan Crowston Franzco, Yoshiaki Kiuchi

Journal article  |  2011  |  Clinical and Experimental Ophthalmology

Long-Term In Vivo Imaging and Measurement of Dendritic Shrinkage of Retinal Ganglion Cells

Christopher Kai-shun Leung, Robert N Weinreb, Zhi Wei Li, Shu Liu, James D Lindsey, Nathan Choi, Lan Liu, Carol Yim-lui Cheung, Cong Ye, Kunliang Qiu, Li Jia Chen, Wing Ho Yung, Jonathan G Crowston, Mingliang Pu, Kwok Fai So, Chi Pui Pang, Dennis Shun Chiu Lam

Journal article  |  2011  |  Investigative Ophthalmology and Visual Science

Acute Primary Angle Closure Attack Does Not Cause an Increased Cup-to-Disc Ratio

Shenton SL Chew, Sushil Vasudevan, Hussain Y Patel, Lulu U Gurria, Nathan M Kerr, Greg Gamble, Jonathan G Crowston, Helen V Danesh-Meyer

Journal article  |  2011  |  Ophthalmology

The Concave Iris in Pigment Dispersion Syndrome

Lance Liu, Ee Lin Ong, Jonathan Crowston

Journal article  |  2011  |  Ophthalmology

Neuroprotection in glaucoma

Sushil K Vasudevan, Viney Gupta, Jonathan G Crowston

Journal article  |  2011  |  Indian Journal of Ophthalmology

Risk factors

JG Crowston, F Lerner, M He, K Singh, P Healey

Book Chapter  |  2011

Mitochondrial disorders and the eye.

Nicole J Van Bergen, Rahul Chakrabarti, Evelyn C O'Neill, Jonathan G Crowston, Ian A Trounce

Journal article  |  2011  |  Eye and Brain

The clinical significance of disturbed mitochondrial function in the eye has emerged since mitochondrial DNA (mtDNA) mutation was ..

The influence of dipalmitoyl phosphatidylserine on phase behaviour of and cellular response to lyotropic liquid crystalline dispersions

Hsin-Hui Shen, Jonathan G Crowston, Florian Huber, Simon Saubern, Keith M McLean, Patrick G Hartley

Journal article  |  2010  |  Biomaterials

Antifibrotic Activity of Bevacizumab on Human Tenon's Fibroblasts In Vitro

Evelyn C O'Neill, Queena Qin, Nicole J Van Bergen, Paul P Connell, Sushil Vasudevan, Michael A Coote, Ian A Trounce, Tina TL Wong, Jonathan G Crowston

Journal article  |  2010  |  Investigative Ophthalmology and Visual Science

WHY IS THE DISC MISSED? - LESSONS FROM THE GONE PROJECT

George Yu Xiang Kong, Lulu Gurria, Evelyn O'Neill, Michael Coote, Jing Xie, Jonathan Crowston

Conference Proceedings  |  2010  |  CLINICAL AND EXPERIMENTAL OPHTHALMOLOGY

MITOCHONDRIAL IMPAIRMENT RESULTS IN INCREASED SUSCEPTIBILITY TO INJURY IN RETINAL NEURONS

George Yu Xiang Kong, Ian Trounce, Bang Bui, Nicole Van Bergen, Vicki Chrysostomou, Hayley Waugh, Algis Vingrys, Jonathan Crowston

Conference Proceedings  |  2010  |  CLINICAL AND EXPERIMENTAL OPHTHALMOLOGY

TEMPORAL PROCESSING DEFICITS IN INDIVIDUALS WITH PRIMARY OPEN ANGLE GLAUCOMA - EVIDENCE FOR BOTH VISUAL AND AUDITORY NEUROPATHY.

Fleur O'Hare, Gary Rance, Allison McKendrick, Jonathan Crowston

Conference Proceedings  |  2010  |  CLINICAL AND EXPERIMENTAL OPHTHALMOLOGY

TRACKING CLINICIAN EYE MOVEMENT IN OPTIC DISC EXAMINATION

Evelyn O'Neill, George Yu Xiang Kong, Danielle Ong, Michael Coote, Jonathan Crowston

Conference Proceedings  |  2010  |  CLINICAL AND EXPERIMENTAL OPHTHALMOLOGY

THE EYEPRESSURE SOFTWARE - A NEW GLAUCOMA MANAGEMENT TOOL FOR CLINICIANS

Michael Coote, George Yu Xiang Kong, Jonathan Crowston

Conference Proceedings  |  2010  |  CLINICAL AND EXPERIMENTAL OPHTHALMOLOGY

Computational Modeling of Fluid Flow and Intra-Ocular Pressure following Glaucoma Surgery

Bruce S Gardiner, David W Smith, Michael Coote, Jonathan G Crowston

Journal article  |  2010  |  PLoS One

Glaucoma: Risk factors and impact of systemic disorders

EC O'Neill, CM Green, JG Crowston

Journal article  |  2010  |  Medicine Today

A Comparison of Differentiation Protocols for RGC-5 Cells

John PM Wood, Glyn Chidlow, Tuyet Tran, Jonathan G Crowston, Robert J Casson

Journal article  |  2010  |  Investigative Ophthalmology and Visual Science

Pediatric Ahmed Valves

Ghee Soon Ang, Jonathan G Crowston, Anthony P Wells

Journal article  |  2010  |  Ophthalmology

Combined diode laser cyclophotocoagulation and intravitreal bevacizumab (Avastin) in neovascular glaucoma

Sudipta Ghosh, Dalveer Singh, Jonathan B Ruddle, Michael Shiu, Michael A Coote, Jonathan G Crowston

Journal article  |  2010  |  Clinical and Experimental Ophthalmology

Intentional and Unintentional Nonadherence to Ocular Hypotensive Treatment in Patients with Glaucoma

Gwyneth Rees, Omega Leong, Jonathan G Crowston, Ecosse L Lamoureux

Journal article  |  2010  |  Ophthalmology

The optic nerve head in acquired optic neuropathies

Evelyn C O'Neill, Helen V Danesh-Meyer, Paul P Connell, Ian A Trounce, Michael A Coote, David A Mackey, Jonathan G Crowston

Journal article  |  2010  |  Nature Reviews Neurology

lntraocular Pressure-Lowering Efficacy of Brinzolamide Compared With Placebo When Added to Travoprost/Timolol Fixed Combination as Adjunctive Therapy in Primary Open-Angle Glaucoma or Ocular Hypertensive Patients

I Goldberg, JG Crowston, B Cvenkel, MC Jasek, JA Stewart, WC Stewart

Conference Proceedings  |  2010  |  INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE

Long Term in vivo Imaging and Measurement of Dendritic Shrinkage of Retinal Ganglion Cells (RGCs)

CK Leung, RN Weinreb, S Liu, C Ye, JD Lindsey, C Pang, JG Crowston, DS Lam

Conference Proceedings  |  2010  |  INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE

Combined Treatment with Bevacizumab and 5-Fluorouracil Attenuates the Postoperative Scarring Response after Experimental Glaucoma Filtration Surgery

Alicia How, Jocelyn Leng Leng Chua, Amanda Charlton, Roseline Su, Marcus Lim, Rajesh S Kumar, Jonathan G Crowston, Tina T Wong

Journal article  |  2010  |  Investigative Ophthalmology and Visual Science

Phosphatidylserine-containing Phytantriol Cubic-Phase Particles: Influence of Lyotropic Liquid Crystalline Phase Behaviour on Cellular Response

HH Shen, JG Crowston, F Huber, KM McLean, S Saubern, PG Hartley

Journal article  |  2010  |  European Cells and Materials

Mechanisms of Retinal Ganglion Cell Injury in Aging and Glaucoma

Vicki Chrysostomou, Ian A Trounce, Jonathan G Crowston

Journal article  |  2010  |  Ophthalmic Research: journal for research in experimental and clinical ophthalmology

Post penetrating keratoplasty glaucoma

V Gupta, S Vasudevan, JG Crowston

Book Chapter  |  2010

Functional Changes in the Retina during and after Acute Intraocular Pressure Elevation in Mice

Yu X Kong, Jonathan G Crowston, Algis J Vingrys, Ian A Trounce, Bang V Bui

Journal article  |  2009  |  Investigative Ophthalmology and Visual Science

Topical prostaglandin analogues do not affect selective laser trabeculoplasty outcomes

D Singh, MA Coote, F O'Hare, MJ Walland, S Ghosh, J Xie, JB Ruddle, JG Crowston

Journal article  |  2009  |  Eye

Readability of prescription labels and medication recall in a population of tertiary referral glaucoma patients

Fleur O'Hare, V Swetha E Jeganathan, Catherine G Rokahr, Sophie L Rogers, Jonathan G Crowston

Journal article  |  2009  |  Clinical and Experimental Ophthalmology

The Relationship of Intraocular Pressure with Age, Systolic Blood Pressure, and Central Corneal Thickness in an Asian Population

Tina T Wong, Tien Y Wong, Paul J Foster, Jonathan G Crowston, Chee-Weng Fong, Tin Aung

Journal article  |  2009  |  Investigative Ophthalmology and Visual Science

Amyloid precursor protein processing and retinal pathology in mouse models of Alzheimer's disease

R Michael Dutescu, Qiao-Xin Li, Jonathan Crowston, Colin L Masters, Paul N Baird, Janetta G Culvenor

Journal article  |  2009  |  Graefe's Archive for Clinical and Experimental Ophthalmology

Recharacterization of the RGC-5 Retinal Ganglion Cell Line

Nicole J Van Bergen, John PM Wood, Glyn Chidlow, Ian A Trounce, Robert J Casson, Won-Kyu Ju, Robert N Weinreb, Jonathan G Crowston

Journal article  |  2009  |  Investigative Ophthalmology and Visual Science

Optic disc morphology - Rethinking shape

Paul G Sanfilippo, Andrea Cardini, Alex W Hewitt, Jonathan G Crowston, David A Mackey

Journal article  |  2009  |  Progress in Retinal and Eye Research

Peripheral Artery Disease and Glaucoma The Singapore Malay Eye Study

V Swetha E Jeganathan, Tien Yin Wong, Paul J Foster, Jonathan G Crowston, Wan Ting Tay, Su Chi Lim, Seang-Mei Saw, E Shyong Tai, Tin Aung

Journal article  |  2009  |  Archives of Ophthalmology

Are failure rates of primary trabeculectomy really increasing? - response

Jonathan G Crowston

Journal article  |  2009  |  Clinical and Experimental Ophthalmology

The optic nerve head in hereditary optic neuropathies

Evelyn C O'Neill, David A Mackey, Paul P Connell, Alex W Hewitt, Helen V Danesh-Meyer, Jonathan G Crowston

Journal article  |  2009  |  Nature Reviews Neuroscience

The Role of Glia, Mitochondria, and the Immune System in Glaucoma

Guelguen Tezel

Journal article  |  2009  |  Investigative Ophthalmology and Visual Science

Mitochondrial Dysfunction and Glaucoma

George YX Kong, Nicole J Van Bergen, Ian A Trounce, Jonathan G Crowston

Journal article  |  2009  |  Journal of Glaucoma

Elevated hydrostatic pressure triggers release of OPA1 and cytochrome C, and induces apoptotic cell death in differentiated RGC-5 cells

Won-Kyu Ju, Keun-Young Kim, James D Lindsey, Mila Angert, Ankur Patel, Ray T Scott, Quan Liu, Jonathan G Crowston, Mark H Ellisman, Guy A Perkins, Robert N Weinreb

Journal article  |  2009  |  Molecular Vision

Wound healing and bleb evaluation after trabeculectomy

A Wells, T Wong, J CROWSTON

Book Chapter  |  2009

Trumpet tension.

Fleur O'Hare, Angus W Turner, Jonathan G Crowston, David Ehrlich

Journal article  |  2009  |  BMJ Case Reports

The case of a 78-year-old man with progressive glaucoma despite seemingly adequate control of his intraocular eye pressure is pres..

Longitudinal Profile of Retinal Ganglion Cell Damage after Optic Nerve Crush with Blue-Light Confocal Scanning Laser Ophthalmoscopy

Christopher Kai-shun Leung, James D Lindsey, Jonathan G Crowston, Lijia Chen, Sylvia Chiang, Robert N Weinreb

Journal article  |  2008  |  Investigative Ophthalmology and Visual Science

Longitudinal Profile of Retinal Ganglion Cell Damage after Optic Nerve Crush with Blue-Light Confocal Scanning Laser Ophthalmoscopy

Christopher Kai-shun Leung, James D Lindsey, Jonathan G Crowston, Chen Lijia, Sylvia Chiang, Robert N Weinreb

Journal article  |  2008  |  Investigative Ophthalmology and Visual Science

Long-term outcomes of trabeculectomy

Jonathan G Crowston

Journal article  |  2008  |  Clinical and Experimental Ophthalmology

Vascular Changes After Intra-bleb Injection of Bevacizumab

Michael A Coote, Jonathan B Ruddle, Queena Qin, Jonathan G Cromston

Journal article  |  2008  |  Journal of Glaucoma

Risk factors for delayed suprachoroidal haemorrhage following glaucoma surgery

VSE Jeganathan, S Ghosh, JB Ruddle, V Gupta, MA Coote, JG Crowston

Journal article  |  2008  |  British Journal of Ophthalmology

In vivo imaging of murine retinal ganglion cells

Christopher KS Leung, James D Lindsey, Jonathan G Crowston, Won-Kyu Ju, Qwan Liu, Dirk-Uwe Bartsch, Robert N Weinreb

Journal article  |  2008  |  Journal of Neuroscience Methods

Estimating the rate of progressive visual field damage in those with open-angle glaucoma, from cross-sectional data

Aimee Teo Broman, Harry A Quigley, Sheila K West, Joanne Katz, Beatriz Munoz, Karen Bandeen-Roche, James M Tielsch, David S Friedman, Jonathan Crowston, Hugh R Taylor, Rohit Varma, M Cristina Leske, Boel Bengtsson, Anders Heijl, Mingguang He, Paul J Foster

Journal article  |  2008  |  Investigative Ophthalmology and Visual Science

Oxidative stress is an early event in hydrostatic pressure-induced retinal ganglion cell damage

Quan Liu, Won-Kyu Ju, Jonathan G Crowston, Fang Xie, George Perry, Mark A Smith, James D Lindsey, Robert N Weinreb

Journal article  |  2007  |  Investigative Ophthalmology and Visual Science

Interferon-alpha and interferon-gamma sensitize human tenon fibroblasts to mitomycin-C

Xiao Yang Wang, Jonathan G Crowston, Hans Zoellner, Paul R Healey

Journal article  |  2007  |  Investigative Ophthalmology and Visual Science

The effect of ICG on mitomycin C cytotoxicity in human tenon fibroblasts

Graham Reeves, Richard Wallis, Jonathan G Crowston, Keith M Small, Anthony P Wells

Journal article  |  2007  |  Journal of Glaucoma

Elevated hydrostatic pressure triggers mitochondrial fission and decreases cellular ATP in differentiated RGC-5 cells

Won-Kyu Ju, Quan Liu, Keun-Young Kim, Jonathan G Crowston, James D Lindsey, Neeraj Agarwal, Mark H Ellisman, Guy A Perkins, Robert N Weinreb

Journal article  |  2007  |  Investigative Ophthalmology and Visual Science

Prostaglandin FP receptors do not contribute to 24-hour intraocular pressure variation in mice

Jonathan G Crowston, Christy A Morris, James D Lindsey, Robert N Weinreb

Journal article  |  2007  |  Investigative Ophthalmology and Visual Science

Intereye spatial relationship of abnormal neuroretinal rim locations in glaucoma patients from the diagnostic innovations in glaucoma study

Esther M Hoffmann, Catherine Boden, Linda M Zangwill, Christopher Bowd, Felipe A Medeiros, Jonathan G Crowston, Pamela A Sample, Robert N Weinreb

Journal article  |  2007  |  American Journal of Ophthalmology

A 1-year study to compare the efficacy and safety of once-daily travoprost 0.004%/timolol 0.5% to once-daily latanoprost 0.005%/timolol 0.5% in patients with open-angle glaucoma or ocular hypertension.

F Topouzis, S Melamed, H Danesh-Meyer, AP Wells, V Kozobolis, H Wieland, R Andrew, D Wells

Journal article  |  2007  |  European Journal of Ophthalmology

PURPOSE: The objective of the study was to compare the intraocular pressure (IOP)-lowering efficacy and safety of travoprost 0.004..

Magnetic resonance imaging of the visual system in vivo: Transsynaptic illumination of V1 and V2 visual cortex

James D Lindsey, Miriam Scadeng, David J Dubowitz, Jonathan G Crowston, Robert N Weinreb

Journal article  |  2007  |  Neuroimage

Direct matrix metalloproteinase enhancement of transscleral permeability

James D Lindsey, Jonathan G Crowston, Ailinh Tran, Christine Morris, Robert N Weinreb

Journal article  |  2007  |  Investigative Ophthalmology and Visual Science

Optic disk size and glaucoma

Esther M Hoffmann, Linda M Zangwill, Jonathan G Crowston, Robert N Weinreb

Journal article  |  2007  |  Survey of Ophthalmology

Flat anterior chamber following phacotrabeculectomy

J CROWSTON, F Li, RN Weinreb

Journal article  |  2007  |  Glaucoma Today

Intravitreal triamcinolone-induced ocular hypertension

JB Ruddle, J CROWSTON, RN Weinreb, CKS Leung

Journal article  |  2007  |  Glaucoma Today

Aqueous humor outflow: what do we know? Where will it lead us?

Michael P Fautsch, Douglas H Johnson

Conference Proceedings  |  2006  |  Investigative Opthalmology & Visual Science

Distribution of optic disc parameters measured by OCT: Findings from a population-based study of 6-year-old Australian children

Son C Huynh, Xiu Ying Wang, Elena Rochtchina, Jonathan G Crowston, Paul Mitchell

Journal article  |  2006  |  Investigative Ophthalmology and Visual Science

Comparison of invasive and non-invasive tonometry in the mouse

Christy A Morris, Jonathan G Crowston, James D Lindsey, John Danias, Robert N Weinreb

Journal article  |  2006  |  Experimental Eye Research

Sustained effect of travoprost on diurnal and nocturnal intraocular pressure

Arthur J Sit, Robert N Weinreb, Jonathan G Crowston, Daniel F Kripke, John HK Liu

Journal article  |  2006  |  American Journal of Ophthalmology

Human serum reduces mitomycin-C cytotoxicity in human tenon's fibroblasts

JG Crowston, XY Wang, PT Khaw, H Zoellner, PR Healey

Journal article  |  2006  |  Investigative Ophthalmology and Visual Science

Effect of bimatoprost on intraocular pressure in prostaglandin FP receptor knockout mice

JG Crowston, JD Lindsey, CA Morris, L Wheeler, FA Medeiros, RN Weinreb

Journal article  |  2005  |  Investigative Ophthalmology and Visual Science

Validation of a predictive model to estimate the risk of conversion from ocular hypertension to glaucoma

FA Medeiros, RN Weinreb, PA Sample, CF Gomi, C Bowd, JG Crowston, LM Zangwill

Journal article  |  2005  |  Archives of Ophthalmology

Unsupervised machine learning with independent component analysis to identify areas of progression in glaucomatous visual fields

PA Sample, C Boden, ZH Zhang, J Pascual, TW Lee, LM Zangwill, RN Weinreb, JG Crowston, EM Hoffmann, FA Medeiros, T Sejnowski, M Goldbaum

Journal article  |  2005  |  Investigative Ophthalmology and Visual Science

Interaction with collagen IV protects lens epithelial cells from Fas-dependent apoptosis by stimulating the production of soluble survival factors

CE Futter, JG Crowston, BDS Allan

Journal article  |  2005  |  Investigative Ophthalmology and Visual Science

Trypan blue identifies antimetabolite treatment area in trabeculectomy

PR Healey, JG Crowston

Journal article  |  2005  |  British Journal of Ophthalmology

Glaucoma medication and aqueous humor dynamics.

Jonathan G Crowston, Robert N Weinreb

Journal article  |  2005  |  Current Opinion in Ophthalmology

PURPOSE OF REVIEW: This review evaluates current concepts regarding the effects of glaucoma medication on aqueous humor dynamics a..

Argon laser iridoplasty in the treatment of plateau-like iris configuration as result of numerous ciliary body cysts

JG Crowston, FA Medeiros, S Mosaed, RN Weinreb

Journal article  |  2005  |  American Journal of Ophthalmology

A pilot study of a system for grading of drainage blebs after glaucoma surgery

AP Wells, JG Crowston, J Marks, JF Kirwan, G Smith, JCK Clarke, R Shah, J Vieira, C Bunce, I Murdoch, PT Khaw

Journal article  |  2004  |  Journal of Glaucoma

Effect of latanoprost on intraocular pressure in mice lacking the prostaglandin FP receptor

JG Crowston, JD Lindsey, M Aihara, RN Weinreb

Journal article  |  2004  |  Investigative Ophthalmology and Visual Science

Late intraocular pressure rise after repeat intravitreal triamcinolone acetonide injections.

Alexander C Lee, Jonathan G Crowston, Michael H Goldbaum, Robert N Weinreb

Journal article  |  2004  |  Seminars in Ophthalmology

MMP inhibition prevents human lens epithelial cell migration and contraction of the lens capsule

TTL Wong, JT Daniels, JG Crowston, PT Khaw

Journal article  |  2004  |  British Journal of Ophthalmology

Confocal scanning laser ophthalmoscopy classifiers and stereophotograph evaluation for prediction of visual field abnormalities in glaucoma-suspect eyes

C Bowd, LM Zangwill, FA Medeiros, JC Hao, K Chan, TW Lee, TJ Sejnowski, MH Goldbaum, PA Sample, JG Crowston, RN Weinreb

Journal article  |  2004  |  Investigative Ophthalmology and Visual Science

Effect of latanoprost on outflow facility in the mouse

JG Crowston, M Aihara, JD Lindsey, RN Weinreb

Journal article  |  2004  |  Investigative Ophthalmology and Visual Science

The effect of optic disc diameter on vertical cup to disc ratio percentiles in a population based cohort: the Blue Mountains Eye Study

JG Crowston, CR Hopley, PR Healey, A Lee, P Mitchell

Journal article  |  2004  |  British Journal of Ophthalmology

Bilateral leukemic orbital infiltration presenting as proptosis and narrow-angle glaucoma

K Tumuluri, T Woo, J Crowston, PR Healey, D Gottlieb, AJ Maloof

Journal article  |  2004  |  Ophthalmic Plastic and Reconstructive Surgery

Water-mediated lysis of lens epithelial cells attached to lens capsule

JG Crowston, PR Healey, C Hopley, G Neilson, EJ Milverton, A Maloof

Journal article  |  2004  |  Journal of Cataract and Refractive Surgery

T lymphocyte mediated lysis of mitomycin C treated Tenon's capsule fibroblasts

JG Crowston, LH Chang, JT Daniels, PT Khaw, AN Akbar

Journal article  |  2004  |  British Journal of Ophthalmology

Evaluating clinical signs in trabeculectomized eyes

JG Crowston, JF Kirwan, A Wells, C Kennedy, IE Murdoch

Journal article  |  2004  |  Eye

The effects of single doses of beta radiation on the wound healing behaviour of human Tenon's capsule fibroblasts

PH Constable, JG Crowston, NL Occleston, PT Khaw

Journal article  |  2004  |  British Journal of Ophthalmology

Water modulation of lens epithelial cells during cataract surgery.

Jonathan G Crowston, Anthony Maloof, Paul R Healey, Geoff Neilson, E John Milverton

Journal article  |  2003  |  Journal of Cataract & Refractive Surgery

Water modulation of lens epithelial cells during cataract surgery

JG Crowston, A Maloof, PR Healey, G Neilson, EJ Milverton

Journal article  |  2003  |  Journal of Cataract and Refractive Surgery

Quantifying corneal endothelial cell death

JG Crowston, PR Healey, A Maloof, B Allan

Journal article  |  2002  |  British Journal of Ophthalmology

In vivo production of interferon beta by human Tenon's fibroblasts; a possible mediator for the development of chronic conjunctival inflammation

L Chang, D Siriwardena, MR Wilkins, JG Crowston, AN Akbar, PT Khaw

Journal article  |  2002  |  British Journal of Ophthalmology

Apoptosis gene expression and death receptor signaling in mitomycin-C-treated human tenon capsule fibroblasts

JG Crowston, LH Chang, PH Constable, JT Daniels, AN Akbar, PT Khaw

Journal article  |  2002  |  Investigative Ophthalmology and Visual Science

Human tenon's fibroblast-produced ifnbeta and the prevention of t-cell apoptosis.

L Chang, JG Crowston, CA Sabin, PT Khaw, AN Akbar

Journal article  |  2001  |  Investigative Ophthalmology and Visual Science

PURPOSE: Fibroblast-T-cell interactions may contribute to the development of chronic inflammation, a risk factor for trabeculectom..

An optometrist's role of co-management in a hospital glaucoma clinic.

MJ Banes, LE Culham, JG Crowston, C Bunce, PT Khaw

Journal article  |  2000  |  Ophthalmic and Physiological Optics

In recent years, optometrists have started to work in some clinical roles in hospital medical clinics. This paper outlines the cur..

Pharmacological mydriasis and optic disc examination.

JF Kirwan, P Gouws, AE Linnell, J Crowston, C Bunce

Journal article  |  2000  |  British Journal of Ophthalmology

AIM: To determine whether pharmacological mydriasis leads to a significant difference in interobserver agreement of optic disc mea..

The role of the immune system in conjunctival wound healing after glaucoma surgery.

L Chang, JG Crowston, MF Cordeiro, AN Akbar, PT Khaw

Journal article  |  2000  |  Survey of Ophthalmology

The immune system has a fundamental role in the development and regulation of ocular healing, which plays an important role in the..

Effects of antimetabolite induced cellular growth arrest on fibroblast-fibroblast interactions.

JT Daniels, NL Occleston, JG Crowston, PT Khaw

Journal article  |  1999  |  Experimental Eye Research

The use of single five-minute applications of antimetabolites during glaucoma filtration surgery has significantly reduced the occ..

Understanding and controlling the scarring response: the contribution of histology and microscopy.

JT Daniels, NL Occleston, JG Crowston, MF Cordeiro, RA Alexander, M Wilkins, R Porter, R Brown, PT Khaw

Journal article  |  1998  |  Microscopy Research and Technique

In response to injury, the body usually initiates a full and swift wound healing response resulting in reconstructed, repaired tis..

Cyclic presentation of central macular oedema.

A Assi, JH Casey, C Davey, J Crowston

Journal article  |  1998  |  Acta Ophthalmologica Scandinavica

We present the case of a young lady with unilateral pars planitis and associated cystoid macular oedema in whom visual symptoms fl..

Long term growth arrest of human Tenon's fibroblasts following single applications of beta radiation.

PH Constable, JG Crowston, NL Occleston, MF Cordeiro, PT Khaw

Journal article  |  1998  |  British Journal of Ophthalmology

AIMS/BACKGROUND: Antimetabolites are increasingly used to manipulate the healing response after filtration surgery, but problems w..

Antimetabolite-induced apoptosis in Tenon's capsule fibroblasts.

JG Crowston, AN Akbar, PH Constable, NL Occleston, JT Daniels, PT Khaw

Journal article  |  1998  |  Investigative Ophthalmology and Visual Science

PURPOSE: To determine whether treatment with mitomycin-c and 5-fluorouracil induces apoptotic death in cultured subconjunctival fi..

Modulating effects of TGF-B I, 2.4 3 and mitomycin-C MMO on conjunctival scarring in the mouse

MF Cordeiro, MB Reichel, F D'Esposito, RA Alexander, JG Crowston, R Ali, SS Bhattacharya, GS Schultz, PT Khaw

Journal article  |  1997  |  Investigative Ophthalmology and Visual Science

The regulation of mitomycin-c indited apoptosis in tenon's fibroblasts

JG Crowston, AN Akbar, PH Constable, NL Occleston, PT Khaw

Journal article  |  1997  |  Investigative Ophthalmology and Visual Science

The effect of but a radiation on the wound healing functions of human Tenon's fibroblasts

PH Constable, JG Crowston, NL Ocdeston, MF Cordeiro, PI Khaw

Journal article  |  1997  |  Investigative Ophthalmology and Visual Science

T-lymphocyte-fibroblast interactions.

JG Crowston, M Salmon, PT Khaw, AN Akbar

Conference Proceedings  |  1997  |  Biochemical Society Transactions

At the end of the immune response, activated T-cells are cleared by apoptosis. T-cell apoptosis induced by cytokine deprivation ca..

Antimetabolites

MR Wilkins, JG Crowston, MF Cordeiro, PT Khaw

Journal article  |  1997  |  Seminars in Ophthalmology

Contact lens care in the unconscious.

J Crowston, L Whitefield, E Gair, J Jagger

Journal article  |  1996  |  The Journal of Trauma: Injury, Infection, and Critical Care

We present a case of gradual visual loss in a patient after a severe road traffic accident. The cause of visual loss was prolonged..

Induction of apoptosis in Tenons fibroblasts with mitomycin C and 5 fluorouracil

JG Crowston, PH Constable, NL Occleston, H Hyde, AN Akbar, PT Khaw

Journal article  |  1996  |  Investigative Ophthalmology and Visual Science

First day follow up for routine phacoemulsification?

L Whitefield, J Crowston, BC Little

Journal article  |  1996  |  British Journal of Ophthalmology

AIMS: To determine the postoperative morbidity on day 1 after uncomplicated phacoemulsification. METHODS: A prospective study was ..

Cavernous sinus syndrome associated with neurocysticercosis.

L Whitefield, JG Crowston, C Davey

Journal article  |  1996  |  Eye

Ophthalmologic features of thallium poisoning.

H Tabandeh, JG Crowston, GM Thompson

Journal article  |  1994  |  American Journal of Ophthalmology

Thallium intoxication is characterized by the development of painful peripheral neuropathy, alopecia, mental disorders, and in sev..

Peak expiratory flow rate and the acute chest syndrome in homozygous sickle cell disease.

EF Bowen, JG Crowston, K De Ceulaer, GR Serjeant

Journal article  |  1991  |  Archives of Disease in Childhood

The peak expiratory flow rate (PEFR) was studied in 20 matched pairs of children with homozygous sickle cell disease with either n..