Peter Mitchell

Intrinsic hospital factors: overlooked cause for variations in delay to transfer for endovascular thrombectomy

Ron Danziger, Christina Tan, Leonid Churilov, Peter Mitchell, Richard Dowling, Steven Bush, Bernard Yan

Journal article  |  2021  |  JOURNAL OF NEUROINTERVENTIONAL SURGERY

BACKGROUND: Intrinsic hospital factors leading to time delay to inter-hospital transfer for endovascular thrombectomy (EVT) have n..

Effect of age and baseline ASPECTS on outcomes in large-vessel occlusion stroke: results from the HERMES collaboration

Johanna Maria Ospel, Manon Kappelhof, Nima Kashani, Bijoy K Menon, Bruce C Campbell, Luis San Roman, Andrew M Demchuk, Diederik WJ Dippel, Jeffrey L Saver, Tudor G Jovin, Peter Mitchell, Serge Bracard, Keith Muir, Phil White, Francis Guillemin, Charles BLM Majoie, Michael D Hill, Scott Brown, Mayank Goyal

Journal article  |  2021  |  JOURNAL OF NEUROINTERVENTIONAL SURGERY

BACKGROUND: Patient age and baseline Alberta Stroke Program Early CT score (ASPECTS) are both independent predictors of outcome in..

Association between pre-treatment perfusion profile and cerebral edema after reperfusion therapies in ischemic stroke.

Felix C Ng, Leonid Churilov, Nawaf Yassi, Timothy J Kleinig, Vincent Thijs, Teddy Y Wu, Darshan Shah, Helen M Dewey, Gagan Sharma, Patricia M Desmond, Bernard Yan, Mark W Parsons, Geoffrey A Donnan, Stephen M Davis, Peter J Mitchell, Bruce Cv Campbell

Journal article  |  2021  |  J Cereb Blood Flow Metab

The relationship between reperfusion and edema is unclear, with experimental and clinical data yielding conflicting results. We in..

Healthy Life-Year Costs of Treatment Speed From Arrival to Endovascular Thrombectomy in Patients With Ischemic Stroke A Meta-analysis of Individual Patient Data From 7 Randomized Clinical Trials

Mohammed A Almekhlafi, Mayank Goyal, Diederik WJ Dippel, Charles BLM Majoie, Bruce CV Campbell, Keith W Muir, Andrew M Demchuk, Serge Bracard, Francis Guillemin, Tudor G Jovin, Peter Mitchell, Philip White, Michael D Hill, Scott Brown, Jeffrey L Saver

Journal article  |  2021  |  JAMA NEUROLOGY

Importance: The benefits of endovascular thrombectomy (EVT) are time dependent. Prior studies may have underestimated the time-ben..

Thrombolysis Guided by Perfusion Imaging up to 9 Hours after Onset of Stroke (vol 380, pg 1795, 2019)

Henry Ma, Bruce CV Campbell, Mark W Parsons, Leonid Churilov, Christopher R Levi, Chung Hsu, Timothy J Kleinig, Tissa Wijeratne, Sami Curtze, Helen M Dewey, Ferdinand Miteff, Chon-Haw Tsai, Jiunn-Tay Lee, Thanh G Phan, Neil Mahant, Mu-Chien Sun, Martin Krause, Jonathan Sturm, Rohan Grimley, Chih-Hung Chen, et al.

Journal article  |  2021  |  NEW ENGLAND JOURNAL OF MEDICINE

Post-Treatment Blood-Brain Barrier Disruption is Associated With Cerebral Edema and Extends Into Penumbral Tissue in Anterior Circulation Large Vessel Occlusion.

Felix Ng, Gagan Sharma, Leonid Churilov, Nawaf Yassi, Timothy Kleinig, Stephen Davis, Peter Mitchell, Richard Leigh, Bruce Campbell

Journal article  |  2021  |  STROKE

Background: Blood Brain Barrier (BBB) disruption is central to vasogenic edema development after ischemia in preclinic..

Does Intravenous Thrombolysis Within 4.5 to 9 Hours Increase Clot Migration Leading to Endovascular Inaccessibility?

Jeremy C Lim, Leonid Churilov, Andrew Bivard, Henry Ma, Richard J Dowling, Bruce C Campbell, Mark W Parsons, Stephen M Davis, Geoffrey A Donnan, Peter J Mitchell, Bernard Yan

Journal article  |  2021  |  STROKE

BACKGROUND AND PURPOSE: Distal clot migration is a recognized event following intravenous thrombolysis (IVT) in the setting of acu..

Motor neuroprosthesis implanted with neurointerventional surgery improves capacity for activities of daily living tasks in severe paralysis: first in-human experience

Thomas J Oxley, Peter E Yoo, Gil S Rind, Stephen M Ronayne, CM Sarah Lee, Christin Bird, Victoria Hampshire, Rahul P Sharma, Andrew Morokoff, Daryl L Williams, Christopher MacIsaac, Mark E Howard, Lou Irving, Ivan Vrljic, Cameron Williams, Sam E John, Frank Weissenborn, Madeleine Dazenko, Anna H Balabanski, David Friedenberg, et al.

Journal article  |  2021  |  JOURNAL OF NEUROINTERVENTIONAL SURGERY

BACKGROUND: Implantable brain-computer interfaces (BCIs), functioning as motor neuroprostheses, have the potential to restore volu..

Computed Tomography Perfusion-Based Machine Learning Model Better Predicts Follow-Up Infarction in Patients With Acute Ischemic Stroke

Hulin Kuang, Wu Qiu, Anna M Boers, Scott Brown, Keith Muir, Charles BLM Majoie, Diederik WJ Dippel, Phil White, Jonathan Epstein, Peter J Mitchell, Antoni Davalos, Serge Bracard, Bruce Campbell, Jeffrey L Saver, Tudor G Jovin, Marta Rubiera, Alexander Khaw, Jai J Shankar, Enrico Fainardi, Michael D Hill, et al.

Journal article  |  2021  |  STROKE

BACKGROUND AND PURPOSE: Prediction of infarct extent among patients with acute ischemic stroke using computed tomography perfusion..

Correlation between CT angiography and digital subtraction angiography in acute ischemic strokes

Su Jin Lee, Belinda Liu, Neil Rane, Peter Mitchell, Richard Dowling, Bernard Yan

Journal article  |  2021  |  CLINICAL NEUROLOGY AND NEUROSURGERY

OBJECTIVE: CT angiography (CTA) is not necessarily performed for all acute ischemic strokes due to variations in national guidelin..