Ken Gayler

Discovery of Inhibitors of Lupin Diadenosine 5 ',5 '''-P-1,P-4-Tetraphosphate Hydrolase by Virtual Screening

Kim M Branson, Haydyn DT Mertens, James D Swarbrick, Jamie I Fletcher, Lukasz Kedzierski, Kenwyn R Gayler, Paul R Gooley, Brian J Smith

Journal article  |  2009  |  Biochemistry

A Comprehensive Bioinformatics Analysis of the Nudix Superfamily in Arabidopsis thaliana

D Gunawardana, VA Likic, KR Gayler

Journal article  |  2009  |  Comparative and Functional Genomics

Identification of functional domains in Arabidopsis thaliana mRNA decapping enzyme (AtDcp2)

Dilantha Gunawardana, Heung-Chin Cheng, Kenwyn R Gayler

Journal article  |  2008  |  Nucleic Acids Research

Therapeutic applications of conotoxins that target the neuronal nicotinic acetylcholine receptor

Bruce G Livett, David W Sandall, David Keays, John Down, Ken R Gayler, Narmatha Satkunanathan, Zeinab Khalil

Journal article  |  2006  |  Toxicon

Alpha-conotoxin Vc1.1 alleviates neuropathic pain and accelerates functional recovery of injured neurones

N Satkunanathan, B Livett, K Gayler, D Sandall, J Down, Z Khalil

Journal article  |  2005  |  Brain Research

Structure and substrate-binding mechanism of human Ap(4)A hydrolase

JD Swarbrick, S Buyya, D Gunawardana, KR Gayler, AG McLennan, PR Gooley

Journal article  |  2005  |  Journal of Biological Chemistry

Molecular prospecting for drugs from the sea

K Gayler, D Sandall, D Greening, D Keays, M Polidano, B Livett, J Down, N Satkunanathan, Z Khalil

Journal article  |  2005  |  IEEE Engineering in Medicine and Biology Magazine

Molecular prospecting for drugs from the sea. Isolating therapeutic peptides and proteins from cone snail venom.

Ken Gayler, David Sandall, David Greening, David Keays, Megan Polidano, Bruce Livett, John Down, Narmatha Satkunanathan, Zeinab Khalil

Journal article  |  2005  |  IEEE engineering in medicine and biology magazine : the quarterly magazine of the Engineering in Medicine & Biology Society

Letter to the Editor: H-1, C-13, and N-15 resonance assignments of the 17 kDa Ap4A hydrolase from Homo sapiens in the presence and absence of ATP

JD Swarbrick, S Buyya, D Gunawardana, JI Fletcher, K Branson, B Smith, S Pepe, A McLennan, KR Gayler, PR Gooley

Journal article  |  2005  |  Journal of Biomolecular NMR

Drugs from the sea: Conopeptides as potential therapeutics

BG Livett, KR Gayler, Z Khalil

Journal article  |  2004  |  Current Medicinal Chemistry

Determining sequences and post-translational modifications of novel conotoxins in Conus victoriae using cDNA sequencing and mass spectrometry

JA Jakubowski, DA Keays, WP Kelley, DW Sandall, JP Bingham, BG Livett, KR Gayler, JV Sweedler

Journal article  |  2004  |  Journal of Mass Spectrometry

A novel alpha-conotoxin identified by gene sequencing is active in suppressing the vascular response to selective stimulation of sensory nerves in vivo

DW Sandall, N Satkunanathan, DA Keays, MA Polidano, X Liping, V Pham, JG Down, Z Khalil, BG Livett, KR Gayler

Journal article  |  2003  |  Biochemistry

The structure of Ap(4)A hydrolase complexed with ATP-MgFx reveals the basis of substrate binding

JI Fletcher, JD Swarbrick, D Maksel, KR Gayler, PR Gooley

Journal article  |  2002  |  Structure

Alpha Conotoxin Peptides with Analgesic Properties

BG LIVETT, Z KHALIL, KR GAYLER, JG DOWN, DW SANDALL, DA KEAYS

Patent  |  2002

Characterization of active-site residues in diadenosine tetraphosphate hydrolase from Lupinus angustifolius

D Maksel, PR Gooley, JD Swarbrick, A Guranowski, C Gange, GM Blackburn, KR Gayler

Journal article  |  2001  |  Biochemical Journal