Lorena Brown

The structure of the influenza A virus genome

Bernadeta Dadonaite, Brad Gilbertson, Michael L Knight, Sanja Trifkovic, Steven Rockman, Alain Laederach, Lorena E Brown, Ervin Fodor, David LV Bauer

Journal article  |  2019  |  Nature Microbiology

Influenza A viruses (IAVs) constitute a major threat to human health. The IAV genome consists of eight single-stranded viral RNA s..

Insights into the Acquisition of Virulence of Avian Influenza Viruses during a Single Passage in Ferrets

Jeffrey Butler, Deborah Middleton, Jessica Haining, Rachel Layton, Steven Rockman, Lorena E Brown, Sandra Sapats

Journal article  |  2019  |  Viruses

Circulating avian influenza viruses pose a significant threat, with human infections occurring infrequently but with potentially s..

Inhibition of Influenza A Virus by Human Infant Saliva

Brad Gilbertson, Kathryn Edenborough, Jodie McVernon, Lorena E Brown

Journal article  |  2019  |  Viruses

Topical application of human-derived Ig isotypes for the control of acute respiratory infection evaluated in a human CD89-expressing mouse model

Sandra Koernig, Ian K Campbell, Charley Mackenzie-Kludas, Alexander Schaub, Marius Loetscher, Wy Ching Ng, Roland Zehnder, Pawel Pelczar, Ildem Sanli, Monther Alhamdoosh, Milica Ng, Lorena E Brown, Fabian Kasermann, Cedric Vonarburg, Adrian W Zuercher

Journal article  |  2019  |  Mucosal Immunology

Inactivated whole virus particle vaccine with potent immunogenicity and limited IL-6 induction is ideal for influenza

Toshiki Sekiya, Edin J Mifsud, Marumi Ohno, Naoki Nomura, Mayumi Sasada, Daisuke Fujikura, Takuji Daito, Masashi Shingai, Yuki Ohara, Tomohiro Nishimura, Masafumi Endo, Ryotarou Mitsumata, Tomio Ikeda, Hironori Hatanaka, Hiroki Kitayama, Kenji Motokawa, Tomoyoshi Sobue, Saori Suzuki, Yasushi Itoh, Lorena E Brown, et al.

Journal article  |  2019  |  Vaccine

Influenza Virus Neuraminidase Structure and Functions

Julie L McAuley, Brad P Gilbertson, Sanja Trifkovic, Lorena E Brown, Jennifer L McKimm-Breschkin

Journal article  |  2019  |  Frontiers in Microbiology

Live Attenuated Influenza Vaccines engineered to express the nucleoprotein of a recent isolate stimulate human influenza CD8( ) T cells more relevant to current infections

D Korenkov, THO Nguyen, I Isakova-Sivak, T Smolonogina, LE Brown, K Kedzierska, L Rudenko

Journal article  |  2018  |  Human Vaccines & Immunotherapeutics

The cell surface mucin MUC1 limits the severity of influenza A virus infection

JL McAuley, L Corcilius, H-X Tan, RJ Payne, MA McGuckin, LE Brown

Journal article  |  2017  |  Mucosal Immunology

Extrinsically derived TNF is primarily responsible for limiting antiviral CD8 T cell response magnitude

Kylie M Quinn, Wan-Ting Kan, Katherine A Watson, Brian J Liddicoat, Natasha G Swan, Hayley McQuilten, Alice E Denton, Jasmine Li, Weisan Chen, Lorena E Brown, David C Jackson, Patrick C Reading, Peter C Doherty, Katherine Kedzierska, Lukasz Kedzierski, Stephen J Turner, Nicole L La Gruta

Journal article  |  2017  |  PLOS ONE

Rapid evolution of the PB1-F2 virulence protein expressed by human seasonal H3N2 influenza viruses reduces inflammatory responses to infection

Julie McAuley, Yi-Mo Deng, Brad Gilbertson, Charley Mackenzie-Kludas, Ian Barr, Lorena Brown

Journal article  |  2017  |  Virology Journal

Mouse Saliva Inhibits Transit of Influenza Virus to the Lower Respiratory Tract by Efficiently Blocking Influenza Virus Neuraminidase Activity

Brad Gilbertson, Wy Ching Ng, Simon Crawford, Jenny L McKimm-Breschkin, Lorena E Brown

Journal article  |  2017  |  Journal of Virology

Salivary Blockade Protects the Lower Respiratory Tract of Mice from Lethal Influenza Virus Infection

Karen Ivinson, Georgia Deliyannis, Leanne McNabb, Lara Grollo, Brad Gilbertson, David Jackson, Lorena E Brown

Journal article  |  2017  |  Journal of Virology

Therapeutic Targeting of the G-CSF Receptor Reduces Neutrophil Trafficking and Joint Inflammation in Antibody-Mediated Inflammatory Arthritis

Ian K Campbell, David Leong, Kirsten M Edwards, Veronika Rayzman, Milica Ng, Gabrielle L Goldberg, Nicholas J Wilson, Karen Scalzo-Inguanti, Charley Mackenzie-Kludas, Kate E Lawlor, Ian P Wicks, Lorena E Brown, Adriana Baz Morelli, Con Panousis, Michael J Wilson, Andrew D Nash, Brent S McKenzie, Arna E Andrews

Journal article  |  2016  |  The Journal of Immunology

Influenza NA and PB1 Gene Segments Interact during the Formation of Viral Progeny: Localization of the Binding Region within the PB1 Gene

Brad Gilbertson, Tian Zheng, Marie Gerber, Anne Printz-Schweigert, Chi Ong, Roland Marquet, Catherine Isel, Steven Rockman, Lorena Brown

Journal article  |  2016  |  Viruses

Induction of memory cytotoxic T cells to influenza A virus and subsequent viral clearance is not modulated by PB1-F2-dependent inflammasome activation

Patricia Hoi Yee Lee, Nicola Bird, Charley MacKenzie-Kludas, Ashley Mansell, Katherine Kedzierska, Lorena Brown, Julie McAuley

Journal article  |  2016  |  Immunology and Cell Biology

Predicting Disease Severity and Viral Spread of H5N1 Influenza Virus in Ferrets in the Context of Natural Exposure Routes

Kathryn M Edenborough, Suzanne Lowther, Karen Laurie, Manabu Yamada, Fenella Long, John Bingham, Jean Payne, Jennifer Harper, Jessica Haining, Rachel Arkinstall, Brad Gilbertson, Deborah Middleton, Lorena E Brown

Journal article  |  2016  |  Journal of Virology

Comparability of neuraminidase inhibition antibody titers measured by enzyme-linked lectin assay (ELLA) for the analysis of influenza vaccine immunogenicity

Maryna C Eichelberger, Laura Couzens, Yonghong Gao, Min Levine, Jacqueline Katz, Ralf Wagner, Catherine I Thompson, Katja Hoeschler, Karen Laurie, Tian Bai, Othmar G Engelhardt, John Wood

Journal article  |  2016  |  Vaccine

Reducing the impact of influenza-associated secondary pneumococcal infections

Edin J Mifsud, Amabel C Tan, Kirsty R Short, Lorena E Brown, Brendon Y Chua, David C Jackson

Journal article  |  2016  |  Immunology & Cell Biology

Inactivated Influenza Vaccine That Provides Rapid, Innate-Immune-System-Mediated Protection and Subsequent Long-Term Adaptive Immunity

Brendon Y Chua, Chinn Yi Wong, Edin J Mifsud, Kathryn M Edenborough, Toshiki Sekiya, Amabel CL Tan, Francesca Mercuri, Steve Rockman, Weisan Chen, Stephen J Turner, Peter C Doherty, Anne Kelso, Lorena E Brown, David C Jackson

Journal article  |  2015  |  mBio

Establishment of functional influenza virus-specific CDS T cell memory pools after intramuscular immunization

Zhongfang Wang, Brendon Y Chua, Javier Vega Ramos, Sergio M Quinones Parra, Emily Fairmaid, Lorena E Brown, David C Jackson, Katherine Kedzierska

Journal article  |  2015  |  Vaccine

Factors associated with transmission of influenza-like illness in a cohort of households containing multiple children

Chelsea R Brown, James M McCaw, Emily J Fairmaid, Lorena E Brown, Karin Leder, Martha Sinclair, Jodie McVernon

Journal article  |  2015  |  Influenza and Other Respiratory Viruses

Host immunological factors enhancing mortality of young adults during the 1918 influenza pandemic

Julie L McAuley, Katherine Kedzierska, Lorena E Brown, G Dennis Shanks

Journal article  |  2015  |  Frontiers in Immunology

Generation of adaptive immune responses following influenza virus challenge is not compromised by pre-treatment with the TLR-2 agonist Pam(2)Cys

Edin Jessica Mifsud, Amabel CL Tan, Lorena Elizabeth Brown, Brendon Yew Loong Chua, David C Jackson

Journal article  |  2015  |  Frontiers in Immunology

Prior Population Immunity Reduces the Expected Impact of CTL-Inducing Vaccines for Pandemic Influenza Control

Kirsty J Bolton, James M McCaw, Lorena Brown, David Jackson, Katherine Kedzierska, Jodie McVernon

Journal article  |  2015  |  PLOS ONE

Different Arms of the Adaptive Immune System Induced by a Combination Vaccine Work in Concert to Provide Enhanced Clearance of Influenza

Joanna CA Cobbin, Weiguang Zeng, David C Jackson, Lorena E Brown

Journal article  |  2014  |  PLoS ONE

Considerations for the rapid deployment of vaccines against H7N9 influenza

Brendon Y Chua, Lorena E Brown, David C Jackson

Journal article  |  2014  |  Expert Review of Vaccines

Influenza Virus PB1 and Neuraminidase Gene Segments Can Cosegregate during Vaccine Reassortment Driven by Interactions in the PB1 Coding Region

Joanna CA Cobbin, Chi Ong, Erin Verity, Brad P Gilbertson, Steven P Rockman, Lorena E Brown

Journal article  |  2014  |  Journal of Virology

Protective efficacy of a bacterially produced modular capsomere presenting M2e from influenza: Extending the potential of broadly cross-protecting epitopes

Nani Wibowo, Fiona K Hughes, Emily J Fairmaid, Linda HL Lua, Lorena E Brown, Anton PJ Middelberg

Journal article  |  2014  |  Vaccine

Universal immunity to influenza must outwit rnmune evasion

Sergio Quinones-Parra, Liyen Loh, Lorena E Brown, Katherine Kedzierska, Sophie A Valkenburg

Journal article  |  2014  |  Frontiers in Microbiology

The Source of the PB1 Gene in Influenza Vaccine Reassortants Selectively Alters the Hemagglutinin Content of the Resulting Seed Virus

Joanna CA Cobbin, Erin E Verity, Brad P Gilbertson, Steven P Rockman, Lorena E Brown

Journal article  |  2013  |  Journal of Virology

Activation of the NLRP3 Inflammasome by IAV Virulence Protein PB1-F2 Contributes to Severe Pathophysiology and Disease

Julie L McAuley, Michelle D Tate, Charley J MacKenzie-Kludas, Anita Pinar, Weiguang Zeng, Andrea Stutz, Eicke Latz, Lorena E Brown, Ashley Mansell

Journal article  |  2013  |  PLoS Pathogens

Serum Amyloid P Is a Sialylated Glycoprotein Inhibitor of Influenza A Viruses

Emma R Job, Barbara Bottazzi, Brad Gilbertson, Kathryn M Edenborough, Lorena E Brown, Alberto Mantovani, Andrew G Brooks, Patrick C Reading

Journal article  |  2013  |  PLoS One

Influenza-Induced Inflammation Drives Pneumococcal Otitis Media

Kirsty R Short, Patrick C Reading, Lorena E Brown, John Pedersen, Brad Gilbertson, Emma R Job, Kathryn M Edenborough, Marrit N Habets, Aldert Zomer, Peter WM Hermans, Dimitri A Diavatopoulos, Odilia L Wijburg

Journal article  |  2013  |  Infection and Immunity

Neuraminidase-Inhibiting Antibody Is a Correlate of Cross-Protection against Lethal H5N1 Influenza Virus in Ferrets Immunized with Seasonal Influenza Vaccine

Steven Rockman, Lorena E Brown, Ian G Barr, Brad Gilbertson, Sue Lowther, Anatoly Kachurin, Olga Kachurina, Jessica Klippel, Jesse Bodle, Martin Pearse, Deborah Middleton

Journal article  |  2013  |  Journal of Virology

Impaired dendritic cell maturation in response to pandemic H1N109 influenza virus

Ruth Chin, Linda Earnest-Silviera, Claire L Gordon, Karen Olsen, Ian Barr, Lorena E Brown, David C Jackson, Joseph Torresi

Journal article  |  2013  |  Journal of Clinical Virology

Influenza-induced, helper-independent CD8( ) T cell responses use CD40 costimulation at the late phase of the primary response

Shirley GK Seah, Jamie L Brady, Emma M Carrington, Wy Ching Ng, Robyn M Sutherland, Manuela S Hancock, Nicole L La Gruta, Lorena E Brown, Stephen J Turner, Andrew M Lew, Yifan Zhan

Journal article  |  2013  |  Journal of Leukocyte Biology

The design and proof of concept for a CD8 T cell-based vaccine inducing cross-subtype protection against influenza A virus

ACL Tan, G Deliyannis, M Bharadwaj, LE Brown, W Zeng, DC Jackson

Journal article  |  2013  |  Immunology and Cell Biology

The design and proof of concept for a CD8( ) T cell-based vaccine inducing cross-subtype protection against influenza A virus

Amabel CL Tan, Georgia Deliyannis, Mandvi Bharadwaj, Lorena E Brown, Weiguang Zeng, David C Jackson

Journal article  |  2013  |  Immunology and Cell Biology

A Mouse Model for the Study of Contact-Dependent Transmission of Influenza A Virus and the Factors That Govern Transmissibility

Kathryn M Edenborough, Brad P Gilbertson, Lorena E Brown

Journal article  |  2012  |  Journal of Virology

Intranasal Administration of the TLR2 Agonist Pam2Cys Provides Rapid Protection against Influenza in Mice

Amabel CL Tan, Edin J Mifsud, Weiguang Zeng, Kathryn Edenborough, Jodie McVernon, Lorena E Brown, David C Jackson

Journal article  |  2012  |  Molecular Pharmaceutics

Induction of Multi-Functional T Cells in a Phase I Clinical Trial of Dendritic Cell Immunotherapy in Hepatitis C Virus Infected Individuals

Shuo Li, Stuart Roberts, Magdalena Plebanski, Maelenn Gouillou, Tim Spelman, Philippe Latour, David Jackson, Lorena Brown, Rosemary L Sparrow, H Miles Prince, Derek Hart, Bruce E Loveland, Eric J Gowans

Journal article  |  2012  |  PLoS One

Unlike CD4( ) T-cell help, CD28 costimulation is necessary for effective primary CD8( ) T-cell influenza-specific immunity

Shirley GK Seah, Emma M Carrington, Wy C Ng, Gabrielle T Belz, Jamie L Brady, Robyn M Sutherland, Manuela S Hancock, Nicole L La Gruta, Lorena E Brown, Stephen J Turner, Yifan Zhan, Andrew M Lew

Journal article  |  2012  |  European Journal of Immunology

Control of pandemic (H1N1) 2009 influenza virus infection of ferret lungs by non-adjuvant-containing pandemic and seasonal vaccines

Steven Rockman, Deborah J Middleton, Martin J Pearse, Ian G Barr, Sue Lowther, Lorena E Brown

Journal article  |  2012  |  Vaccine

Abortive Replication of Influenza Virus in Mouse Dendritic Cells

Lisa J Ioannidis, Erin E Verity, Simon Crawford, Steven P Rockman, Lorena E Brown

Journal article  |  2012  |  Journal of Virology

Nanopatch targeted delivery of both antigen and adjuvant to skin synergistically drives enhanced antibody responses

Germain JP Fernando, Xianfeng Chen, Clare A Primiero, Sally R Yukiko, Emily J Fairmaid, Holly J Corbett, Ian H Frazer, Lorena E Brown, Mark AF Kendall

Journal article  |  2012  |  Journal of Controlled Release

Rapid kinetics to peak serum antibodies is achieved following influenza vaccination by dry-coated densely packed microprojections to skin

Xianfeng Chen, Germain JP Fernando, Anthony P Raphael, Sally R Yukiko, Emily J Fairmaid, Clare A Primiero, Ian H Frazer, Lorena E Brown, Mark AF Kendall

Journal article  |  2012  |  Journal of Controlled Release

Improving the reach of vaccines to low-resource regions, with a needle-free vaccine delivery device and long-term thermostabilization

Xianfeng Chen, Germain JP Fernando, Michael L Crichton, Christopher Flaim, Sally R Yukiko, Emily J Fairmaid, Holly J Corbett, Clare A Primiero, Alexander B Ansaldo, Ian H Frazer, Lorena E Brown, Mark AF Kendall

Journal article  |  2011  |  Journal of Controlled Release

The linear range for accurately quantifying antigen-specific T-cell frequencies by tetramer staining during natural immune responses

Shirley GK Seah, Robyn M Sutherland, Nicole L La Gruta, Lorena E Brown, Emma M Carrington, Gabrielle T Belz, Jamie L Brady, Stephen J Turner, Yifan Zhan, Andrew M Lew

Journal article  |  2011  |  European Journal of Immunology

Universal vaccination: is this premature with current vaccine approaches?

Lorena Brown, Joanna Cobbin, Deborah Middleton, Ian Barr, Weiguang Zeng, David Jackson

Journal article  |  2011  |  Influenza and Other Respiratory Viruses

Route of H5N1 exposure in ferrets affects pathogenesis and severity of disease

Kathryn Edenborough, Manabu Yamada, Sue Lowther, John Bingham, Jessica Haining, Brad Gilbertson, Deborah Middleton, Lorena Brown

Journal article  |  2011  |  Influenza and Other Respiratory Viruses

Using Bioluminescent Imaging to Investigate Synergism Between Streptococcus pneumoniae and Influenza A Virus in Infant Mice

Kirsty R Short, Dimitri A Diavatopoulos, Patrick C Reading, Lorena E Brown, Kelly L Rogers, Richard A Strugnell, Odilia LC Wijburg

Journal article  |  2011  |  Journal of Visualized Experiments

The Role of Neutrophils during Mild and Severe Influenza Virus Infections of Mice

Michelle D Tate, Lisa J Ioannidis, Ben Croker, Lorena E Brown, Andrew G Brooks, Patrick C Reading

Journal article  |  2011  |  PLoS One

Site-Selectively Coated, Densely-Packed Microprojection Array Patches for Targeted Delivery of Vaccines to Skin

Xianfeng Chen, Holly J Corbett, Sally R Yukiko, Anthony P Raphael, Emily J Fairmaid, Tarl W Prow, Lorena E Brown, Germain JP Fernando, Mark AF Kendall

Journal article  |  2011  |  Advanced Functional Materials

The role of adjuvants in vaccines for seasonal and pandemic influenza

Lorena E Brown

Journal article  |  2010  |  Vaccine

Prevention and Treatment of Influenza with Hyperimmune Bovine Colostrum Antibody

Wy Ching Ng, Victor Wong, Brian Muller, Grant Rawlin, Lorena E Brown

Journal article  |  2010  |  PLoS One

Pre-pandemic and pandemic influenza vaccines

Steven Rockman, Lorena Brown

Journal article  |  2010  |  Human Vaccines

A phase I clinical trial of dendritic cell immunotherapy in HCV-infected individuals

Eric J Gowans, Stuart Roberts, Kathryn Jones, Irene Dinatale, Philippe A Latour, Brendan Chua, Emily MY Eriksson, Ruth Chin, Shuo Li, Dominic M Wall, Rosemary L Sparrow, Jude Moloney, Maureen Loudovaris, Rosemary Ffrench, H Miles Prince, Derek Hart, Weng Zeng, Joseph Torresi, Lorena E Brown, David C Jackson

Journal article  |  2010  |  Journal of Hepatology

A lipopeptide based on the M2 and HA proteins of influenza A viruses induces protective antibody

David Pejoski, Weiguang Zeng, Steven Rockman, Lorena E Brown, David C Jackson

Journal article  |  2010  |  Immunology and Cell Biology

Influenza A virus facilitates Streptococcus pneumoniae transmission and disease

Dimitri A Diavatopoulos, Kirsty R Short, John T Price, Jonathan J Wilksch, Lorena E Brown, David E Briles, Richard A Strugnell, Odilia L Wijburg

Journal article  |  2010  |  FASEB Journal

Potent Immunity to Low Doses of Influenza Vaccine by Probabilistic Guided Micro-Targeted Skin Delivery in a Mouse Model

Germain JP Fernando, Xianfeng Chen, Tarl W Prow, Michael L Crichton, Emily J Fairmaid, Michael S Roberts, Ian H Frazer, Lorena E Brown, Mark AF Kendall

Journal article  |  2010  |  PLoS One

The role of adjuvants in vaccines for seasonal and pandemic influenza

L BROWN

Journal article  |  2010  |  Vaccine

Neoepitope Antibodies Against MMP-Cleaved and Aggrecanase-Cleaved Aggrecan

Amanda J Fosang, Karena Last, Heather Stanton, Suzanne B Golub, Christopher B Little, Lorena Brown, David C Jackson

Book Chapter  |  2010  |  Methods in Molecular Biology

Role of CD8( ) T-cell immunity in influenza infection: potential use in future vaccine development.

Nicole La Gruta, Anne Kelso, Lorena E Brown, Wiesan Chen, David C Jackson, Stephen J Turner

Journal article  |  2009  |  Expert Review of Respiratory Medicine

Continued circulation of the highly pathogenic avian H5N1 influenza A virus has many people worried that an influenza pandemic is ..

Evaluation of Vaccines for H5N1 Influenza Virus in Ferrets Reveals the Potential for Protective Single-Shot Immunization

Deborah Middleton, Steven Rockman, Martin Pearse, Ian Barr, Sue Lowther, Jessica Klippel, David Ryan, Lorena Brown

Journal article  |  2009  |  Journal of Virology

Lipopeptide vaccines illustrate the potential role of subtype-crossreactive T cells in the control of highly virulent influenza

Wy Ching Ng, Brad Gilbertson, Bock Lim, Weiguang Zeng, David C Jackson, Lorena E Brown

Journal article  |  2009  |  Influenza and Other Respiratory Viruses

Prospects for an influenza vaccine that induces cross-protective cytotoxic T lymphocytes

Lorena E Brown, Anne Kelso

Journal article  |  2009  |  Immunology and Cell Biology

Single dose intranasal immunization with ISCOMATRIX (TM) vaccines to elicit antibody-mediated clearance of influenza virus requires delivery to the lower respiratory tract

Megan T Sanders, Georgia Deliyannis, Martin J Pearse, Michael K McNamara, Lorena E Brown

Journal article  |  2009  |  Vaccine

Immunity to avian influenza A viruses

PC Doherty, LE Brown, A Kelso, PG Thomas

Journal article  |  2009  |  OIE Revue Scientifique et Technique

Selected Toll-like Receptor Ligands and Viruses Promote Helper-Independent Cytotoxic T Cell Priming by Upregulating CD40L on Dendritic Cells

Susan Johnson, Yifan Zhan, Robyn M Sutherland, Adele M Mount, Sammy Bedoui, Jamie L Brady, Emma M Carrington, Lorena E Brown, Gabrielle T Belz, William R Heath, Andrew M Lew

Journal article  |  2009  |  Immunity

Q&A: What have we found out about the influenza A (H1N1) 2009 pandemic virus?

S TURNER, L BROWN, P DOHERTY, A Kelso

Journal article  |  2009  |  Journal of Biology

Q&A: What have we found out about the influenza A (H1N1) 2009 pandemic virus?

Stephen J Turner, Lorena E Brown, Peter C Doherty, Anne Kelso

Journal article  |  2009  |  Journal of Biology

Targeting subcapsular antigens for prevention of Klebsiella pneumoniae infections

Abigail Clements, Adam W Jenney, Jacinta L Farn, Lorena E Brown, Georgia Deliyannis, Elizabeth L Hartland, Martin J Pearse, Margaret B Maloney, Steven L Wesselingh, Odilia L Wijburg, Richard A Strugnell

Journal article  |  2008  |  Vaccine

Human dendritic cells pulsed with specific lipopeptides stimulate autologous antigen-specific T cells without the addition of exogenous maturation factors

KL Jones, LE Brown, EMY Eriksson, RA Ffrench, PA Latour, BE Loveland, DM Wall, SK Roberts, DC Jackson, EJ Gowans

Journal article  |  2008  |  Journal of Viral Hepatitis

A self-adjuvanting lipopeptide-based vaccine candidate for the treatment of hepatitis C virus infection

Brendon Y Chua, Emily M Eriksson, Lorena E Brown, Weiguang Zeng, Eric J Gowans, Joseph Torresi, David C Jackson

Journal article  |  2008  |  Vaccine

Antiviral activity of the long chain pentraxin PTX3 against influenza viruses

Patrick C Reading, Silvia Bozza, Brad Gilbertson, Michelle Tate, Silvia Moretti, Emma R Job, Erika C Crouch, Andrew G Brooks, Lorena E Brown, Barbara Bottazzi, Luigina Romani, Alberto Mantovani

Journal article  |  2008  |  Journal of Immunology

Lipopeptide Vaccines Illustrate the Potential Role of Subtype-Crossreactive T Cell Responses in the Control of Seasonal and Pandemic Influenza

L BROWN, G Deliyannis, K KEDZIERSKA, YF LAU, WC NG, W ZENG, B GILBERTSON, B LIM, JCA COBBIN, D JACKSON, S TURNER, A KELSO

Conference Proceedings  |  2008  |  Options for the Control of Influenza VI

Antitumor activity of dual-specific T cells and influenza virus

A Murphy, JA Westwood, LE Brown, MWL Teng, M Moeller, Y Xu, MJ Smyth, P Hwu, PK Darcy, MH Kershaw

Journal article  |  2007  |  Cancer Gene Therapy

Susceptibility of highly pathogenic A(H5N1) avian influenza viruses to the neuraminidase inhibitors and adamantanes

AC Hurt, P Selleck, N Komadina, R Shaw, L Brown, IG Barr

Journal article  |  2007  |  Antiviral Research

Lipid-containing mimetics of natural triggers of innate immunity as CTL-inducing influenza vaccines

Yuk Fai Lau, Georgia Deliyannis, Weiguang Zeng, Ashley Mansell, David C Jackson, Lorena E Brown

Journal article  |  2006  |  International Immunology

Pandemic vaccines: Promises and pitfalls

R Booy, LE Brown, GS Grohmann, CR MacIntyre

Journal article  |  2006  |  Medical Journal of Australia

Pandernic vaccines: promises and pitfalls

Robert Booy, Lorena E Brown, Gary S Grohmann, C Raina MacIntyre

Journal article  |  2006  |  The Medical journal of Australia

Intranasal lipopeptide primes lung-resident memory CD8( ) T cells for long-term pulmonary protection against influenza

G Deliyannis, K Kedzierska, YF Lau, WG Zeng, SJ Turner, DC Jackson, LE Brown

Journal article  |  2006  |  European Journal of Immunology

Targeting CD45RB alters T cell migration and delays viral clearance

B Lim, RM Sutherland, YF Zhan, G Deliyannis, LE Brown, AM Lew

Journal article  |  2006  |  International Immunology

Determinants of immunity to influenza

L BROWN

Journal article  |  2006  |  Microbiology Australia

Pandemic vaccines: promises and pitfalls

R Booy, L BROWN, G Grohmann, C MacIntyre

Journal article  |  2006  |  Microbiology Australia

Enrichment of selenium in milk protein linearly increases blood selenium and improves immune function

J COTTRELL, EJ Milne, M Menidis, LE Brown, FR Dunshea, GP Walker, HS Gill

Conference Proceedings  |  2006

Treatment with antibody to CD45RB delays but does not abrogate clearance of influenza virus

B Lim, RM Sutherland, Y Zhan, G Deliyannis, LE Brown, AM Lew

Conference Proceedings  |  2005  |  TISSUE ANTIGENS

Lipid-based self-adjuvanting vaccines.

Lorena E Brown, David C Jackson

Journal article  |  2005  |  Current Drug Delivery

Lipopeptides incorporating epitopes for CD4+ T cells and either CD8+ T cells or B cells have proven to be immunogenic in animal mo..

Enumeration and characterization of virus-specific B cells by multicolor flow cytometry

VP Doucett, W Gerhard, K Owler, D Curry, L Brown, N Baumarth

Journal article  |  2005  |  Journal of Immunological Methods

ISCOM (TM)-based vaccines: The second decade

MT Sanders, LE Brown, G Deliyannis, MJ Pearse

Journal article  |  2005  |  Immunology and Cell Biology

A totally synthetic vaccine of generic structure that targets Toll-like receptor 2 on dendritic cells and promotes antibody or cytotoxic T cell responses

DC Jackson, YF Lau, T Le, A Suhrbier, G Deliyannis, C Cheers, C Smith, WG Zeng, LE Brown

Journal article  |  2004  |  Proceedings of the National Academy of Sciences

Responses against complex antigens in various models of CD4 T-cell deficiency - Surprises from an anti-CD4 antibody transgenic mouse

YF Zhan, LE Brown, G Deliyannis, S Seah, OL Wijburg, J Price, RA Strugnell, PJ O'Connell, AM Lew

Journal article  |  2004  |  Immunol. Res.

Responses Against Complex Antigens in Various Models of CD4 T-Cell Deficiency

Y Zhan, LE BROWN, G DELIYANNIS, GKS SEAH, OL WIJBURG, JD PRICE, RA STRUGNELL, PJ O'Connell, AM LEW

Journal article  |  2004  |  Immunologic Research

A totally synthetic vaccine of generic structure that targets TLR2 dendritic cells and promotes either antibody or CTL responses

D JACKSON, YF LAU, undefined Le, undefined Suhrbier, G DELIYANNIS, C CHEERS, CD SMITH, W ZENG, L BROWN

Journal article  |  2004  |  Proceedings of the National Academy of Sciences of the United States of America

Costimulatory requirements of anti-influenza CD8( ) T cell responses

SGK Seah, G Deliyannis, Y Zhan, AM Lew, LE Brown

Conference Proceedings  |  2003  |  JOURNAL OF CLINICAL VIROLOGY

Single-cell perforin and granzyme expression reveals the anatomical localization of effector CD8( ) T cells in influenza virus-infected mice

BJ Johnson, EO Costelloe, DR Fitzpatrick, JBAG Haanen, TNM Schumacher, LE Brown, A Kelso

Journal article  |  2003  |  Proceedings of the National Academy of Sciences of the United States of America

Immune responses in hepatitis C virus infection: The role of dendritic cells

NL Fowler, J Torresi, DC Jackson, LE Brown, EJ Gowans

Journal article  |  2003  |  Immunology and Cell Biology

Maturation of dendritic cells with lipopeptides that represent vaccine candidates for hepatitis C virus

BY Chua, A Healy, PU Cameron, O Stock, M Rizkalla, WG Zeng, J Torresi, LE Brown, NL Fowler, EJ Gowans, DC Jackson

Journal article  |  2003  |  Immunology and Cell Biology

Highly immunogenic and totally synthetic lipopeptides as self-adjuvanting immunocontraceptive vaccines

WG Zeng, S Ghosh, YF Lau, LE Brown, DC Jackson

Journal article  |  2002  |  Journal of Immunology

Identification of antigenically active tryptic fragments of apical membrane antigen-1 (AMA1) of Plasmodium chabaudi malaria: strategies for assembly of immunologically active peptides

D Salvatore, AN Hodder, WG Zeng, LE Brown, RF Anders, DC Jackson

Journal article  |  2002  |  Vaccine

Induction of long-term memory CD8( ) T cells for recall of viral clearing responses against influenza virus

G Deliyannis, DC Jackson, NJ Ede, WG Zeng, I Hourdakis, E Sakabetis, LE Brown

Journal article  |  2002  |  Journal of Virology

A 320-kilobase artificial chromosome encoding the human HLA DR3-DQ2 MHC haplotype confers HLA restriction in transgenic mice

ZJ Chen, N Dudek, O Wijburg, R Strugnell, L Brown, G Deliyannis, D Jackson, F Koentgen, T Gordon, J McCluskey

Journal article  |  2002  |  Journal of Immunology

Differential effect of CD8( ) and CD8(-) dendritic cells in the stimulation of secondary CD4( ) T cells

V Kronin, CJ Fitzmaurice, I Caminschi, K Shortman, DC Jackson, LE Brown

Journal article  |  2001  |  International Immunology

Synthetic peptide and their polymers as vaccines

D Jackson, E Brandt, L Brown, G Deliyannis, C Fitzmaurice, S Ghosh, M Good, L Harling-McNabb, D Dadley-Moore, J Pagnon, K Sadler, D Salvatore, W Zeng

Conference Proceedings  |  2001  |  BIOMEDICAL POLYMERS AND POLYMER THERAPEUTICS

Antibodies to MMP-cleaved aggrecan.

AJ Fosang, K Last, DC Jackson, L Brown

Journal article  |  2001  |  Methods in Molecular Biology

Lipopeptide vaccines: a strategy for improving protective immunity against influenza

G Deliyannis, DC Jackson, L Harling-McNabb, WG Zeng, NJ Ede, I Hourdakis, M Rudd, A Kelso, LE Brown

Conference Proceedings  |  2001  |  International Congress Series

Antigenic Competition

JD HUNT, LE BROWN, DC JACKSON

Scholarly edition  |  2001

Trichostrongylus colubriformis extract upregulates TNF-alpha receptor expression and enhances TNF-alpha sensitivity of L929 cells

MC Riffkin, HF Seow, PR Wood, LE Brown, DC Jackson, JPY Scheerlinck

Journal article  |  2000  |  Immunology and Cell Biology

B-1 and B-2 cell-derived immunoglobulin M antibodies are nonredundant components of the protective response to influenza virus infection

N Baumgarth, OC Herman, GC Jager, LE Brown, LA Herzenberg, JZ Chen

Journal article  |  2000  |  The Journal of Experimental Medicine

A fusion DNA vaccine that targets antigen-presenting cells increases protection from viral challenge

G Deliyannis, JS Boyle, JL Brady, LE Brown, AM Lew

Journal article  |  2000  |  Proceedings of the National Academy of Sciences

The geometry of synthetic peptide-based immunogens affects the efficiency of T cell stimulation by professional antigen-presenting cells

CJ Fitzmaurice, LE Brown, V Kronin, DC Jackson

Journal article  |  2000  |  International Immunology

Totally synthetic lipid-containing polyoxime peptide constructs are potent immunogens

WG Zeng, DC Jackson, J Murray, K Rose, LE Brown

Journal article  |  2000  |  Vaccine

The antigenic and immunogenic properties of synthetic peptide immunocontraceptive vaccine candidates based on gamete antigens

K Sadler, PH Bird, LE Brown, DC Jackson

Journal article  |  1999  |  Vaccine

Preparation and properties of totally synthetic immunogens

DC Jackson, CJ Fitzmaurice, LE Brown, WG Zeng

Journal article  |  1999  |  Vaccine

Mice lacking the transcription factor subunit Rel can clear an influenza infection and have functional anti-viral cytotoxic T cells but do not develop an optimal antibody response

L Harling-McNabb, G Deliyannis, DC Jackson, S Gerondakis, G Grigoriadis, LE Brown

Journal article  |  1999  |  International Immunology

Innate and acquired humoral immunities to influenza virus are mediated by distinct arms of the immune system

N Baumgarth, OC Herman, GC Jager, L Brown, LA Herzenberg, LA Herzenberg

Journal article  |  1999  |  Proceedings of the National Academy of Sciences

Induction of autoimmunity by multivalent immunodominant and subdominant T cell determinants of La (SS-B)

AD Farris, L Brown, P Reynolds, JB Harley, JA James, RH Scofield, J McCluskey, TP Gordon

Journal article  |  1999  |  Journal of Immunology

Immunopotentiation of humoral and cellular responses to inactivated influenza vaccines by two different adjuvants with potential for human use

G Deliyannis, DC Jackson, W Dyer, J Bates, A Coulter, L Harling-McNabb, LE Brown

Journal article  |  1998  |  Vaccine

Delivery of multiple CD8 cytotoxic T cell epitopes by DNA vaccination

SA Thomson, MA Sherritt, J Medveczky, SL Elliott, DJ Moss, GJP Fernando, LE Brown, A Suhrbier

Journal article  |  1998  |  Journal of Immunology

Free radical induced polymerization of synthetic peptides into polymeric immunogens

DC Jackson, N OBrienSimpson, NJ Ede, LE Brown

Journal article  |  1997  |  Vaccine

T-helper cell interactions with multivalent determinants of La (SS-B)

AD Farris, J McCluskey, P Reynolds, L Brown, J James, JB Harley, TP Gordon

Journal article  |  1997  |  ARTHRITIS AND RHEUMATISM

Polymerization of unprotected synthetic peptides: A view toward synthetic peptide vaccines

NM OBrienSimpson, NJ Ede, LE Brown, J Swan, DC Jackson

Journal article  |  1997  |  Journal of the American Chemical Society

Defence against the immune barrage: Helminth survival strategies

M Riffkin, HF Seow, D Jackson, L Brown, P Wood

Journal article  |  1996  |  Immunology and Cell Biology

The assembly and immunological properties of non-linear synthetic immunogens containing T-cell and B-cell determinants

CJ Fitzmaurice, LE Brown, TL McInerney, DC Jackson

Journal article  |  1996  |  Vaccine

Manipulation of the helper T cell response to influence antigenic competition occurring with a multivalent vaccine

JD Hunt, LE Brown, PR Wood, DJ Stewart, DC Jackson

Journal article  |  1996  |  Immunology and Cell Biology

Options for the Control of Influenza

Lorena E Brown, Alan W Hampson, Robert G Webster

Book  |  1996

Contains proceedings of: 1985, Viratek-UCLA Symposium; 1992-1996, International Conference on Options for the Control of Influenza..

Synthetic peptide determinants for CD4( ) T cells as immunogens to study the importance of pre-existing helper T cell immunity in influenza

LE Brown, L Stephens, DC Jackson

Conference Proceedings  |  1996  |  OPTIONS FOR THE CONTROL OF INFLUENZA III

Immunological parameters associated with antigenic competition in a multivalent footrot vaccine

JD Hunt, DC Jackson, PR Wood, DJ Stewart, LE Brown

Journal article  |  1995  |  Vaccine

A synthetic peptide-based polyoxime vaccine construct of high purity and activity

K Rose, WG Zeng, LE Brown, DC Jackson

Journal article  |  1995  |  Molecular Immunology

ANALYSIS OF THE REQUIREMENTS FOR CLASS II-RESTRICTED T-CELL RECOGNITION OF A SINGLE DETERMINANT REVEALS CONSIDERABLE DIVERSITY IN THE T-CELL RESPONSE AND DEGENERACY OF PEPTIDE BINDING TO I-E(D1)

AM FAHRER, HM GEYSEN, DO WHITE, DC JACKSON, LE BROWN

Journal article  |  1995  |  Journal of Immunology

DEVELOPMENT OF A CLEAVAGE-SITE-SPECIFIC MONOCLONAL-ANTIBODY FOR DETECTING METALLOPROTEINASE-DERIVED AGGRECAN FRAGMENTS - DETECTION OF FRAGMENTS IN HUMAN SYNOVIAL-FLUIDS

AJ FOSANG, K LAST, P GARDINER, DC JACKSON, L BROWN

Journal article  |  1995  |  Biochemical Journal

SYNTHETIC PEPTIDES REPRESENTING SEQUENCES WITHIN GP41 OF HIV AS IMMUNOGENS FOR MURINE T-CELL AND B-CELL RESPONSES

LE BROWN, DO WHITE, C AGIUS, BE KEMP, N YATZAKIS, P POUMBOURIOS, DA MCPHEE, DC JACKSON

Journal article  |  1995  |  Archives of Virology

Antigenic and immunogenic properties of synthetic peptide-based T-cell determinant polymers.

DC Jackson, C Fitzmaurice, RC Sheppard, J McMurray, LE Brown

Journal article  |  1995  |  Biomedical peptides, proteins & nucleic acids : structure, synthesis & biological activity

Presentation of T-cell determinants to the immune system in multimeric form has clear advantages and the production of synthetic p..

NOVEL FEATURES OF THE RESPIRATORY-TRACT T-CELL RESPONSE TO INFLUENZA-VIRUS INFECTION - LUNG T-CELLS INCREASE EXPRESSION OF GAMMA-INTERFERON MESSENGER-RNA IN-VIVO AND MAINTAIN HIGH-LEVELS OF MESSENGER-RNA EXPRESSION FOR INTERLEUKIN-5 (IL-5) AND IL-10

N BAUMGARTH, L BROWN, D JACKSON, A KELSO

Journal article  |  1994  |  Journal of Virology

ANTIGENIC-COMPETITION IN A MULTIVALENT FOOT ROT VACCINE

JD HUNT, DC JACKSON, LE BROWN, PR WOOD, DJ STEWART

Journal article  |  1994  |  Vaccine

ANALYSIS OF ANTIBODY-ANTIGEN AND ANTIBODY ANTI-(IDIOTYPIC ANTIBODY) CROSS-REACTIVITY USING SYNTHETIC PEPTIDE PROBES

TL MCINERNEY, LE BROWN, VR SUTTON, DC JACKSON

Journal article  |  1994  |  Molecular Immunology

GLYCOSYLATION OF A SYNTHETIC PEPTIDE REPRESENTING A T-CELL DETERMINANT OF INFLUENZA-VIRUS HEMAGGLUTININ RESULTS IN LOSS OF RECOGNITION BY CD4( ) T-CELL CLONES

DC JACKSON, HE DRUMMER, L URGE, L OTVOS, LE BROWN

Journal article  |  1994  |  Virology

Conserved determinants for CD4 T cells within the light chain of the H3 hemagglutinin molecule of influenza virus.

DC Jackson, HE Drummer, LE Brown

Journal article  |  1994  |  Virology

Helper T-cell clones were isolated from BALB/c mice that had been inoculated with purified light chain (HA2) from H3 subtype influ..

CONSERVED DETERMINANTS FOR CD4( ) T-CELLS WITHIN THE LIGHT-CHAIN OF THE H3 HEMAGGLUTININ MOLECULE OF INFLUENZA-VIRUS

DC JACKSON, HE DRUMMER, LE BROWN

Journal article  |  1994  |  Virology

A STUDY OF THE ADVANTAGES AND LIMITATIONS OF IMMUNOBLOTTING PROCEDURES FOR THE DETECTION OF ANTIBODIES AGAINST INFLUENZA-VIRUS

GP KAPAKLISDELIYANNIS, HE DRUMMER, LE BROWN, GA TANNOCK, DC JACKSON

Conference Proceedings  |  1993  |  Electrophoresis

CONSERVATION OF DETERMINANTS FOR CLASS II-RESTRICTED T-CELLS WITHIN SITE-E OF INFLUENZA-VIRUS HEMAGGLUTININ AND FACTORS INFLUENCING THEIR EXPRESSION

LE BROWN, DO WHITE, DC JACKSON

Journal article  |  1993  |  Journal of Virology

MODULATION OF CD4 T-CELL RECOGNITION OF INFLUENZA HEMAGGLUTININ BY CARBOHYDRATE SIDE-CHAINS LOCATED OUTSIDE A T-CELL DETERMINANT

HE DRUMMER, DC JACKSON, LE BROWN

Journal article  |  1993  |  Virology

ANTIGENIC-COMPETITION - THE PROPERTIES OF A MULTIVALENT FOOTROT VACCINE

JD HUNT, DC JACKSON, LE BROWN, PR WOOD, DJ STEWART

Journal article  |  1993  |  JOURNAL OF LEUKOCYTE BIOLOGY

EXTENSION OF A MINIMAL T-CELL DETERMINANT ALLOWS RELAXATION OF THE REQUIREMENT FOR PARTICULAR RESIDUES WITHIN THE DETERMINANT

LE BROWN, DC JACKSON, G TRIBBICK, DO WHITE, HM GEYSEN

Journal article  |  1991  |  International Immunology

PROBING THE IDIOTYPE ANTIIDIOTYPE ANTIBODY INTERACTION WITH A SET OF SYNTHETIC PEPTIDE HOMOLOGS

LE BROWN, T MCINERNEY, EM ANDERS, DO WHITE, DC JACKSON

Journal article  |  1991  |  Immunology Letters

A synthetic peptide of influenza virus hemagglutinin as a model antigen and immunogen.

DC Jackson, LE Brown

Journal article  |  1991  |  Peptide research

This paper reviews our studies on a 24-residue synthetic peptide representing part of the amino acid sequence of the influenza vir..

THE STOICHIOMETRY OF BINDING BETWEEN MONOCLONAL-ANTIBODY MOLECULES AND THE HEMAGGLUTININ OF INFLUENZA-VIRUS

P POUMBOURIOS, LE BROWN, DO WHITE, DC JACKSON

Journal article  |  1990  |  Virology

IMMUNOCHEMICAL AND CRYSTALLOGRAPHIC STUDIES ON THE INTERACTION BETWEEN ANTIBODY AND A SYNTHETIC PEPTIDE OF INFLUENZA HEMAGGLUTININ

DC JACKSON, VM ZUBAK, SM DAYAN, LE BROWN

Conference Proceedings  |  1990  |  USE OF X-RAY CRYSTALLOGRAPHY IN THE DESIGN OF ANTIVIRAL AGENTS

AN ANALYSIS OF THE PROPERTIES OF MONOCLONAL-ANTIBODIES DIRECTED TO EPITOPES ON INFLUENZA-VIRUS HEMAGGLUTININ

LE BROWN, JM MURRAY, DO WHITE, DC JACKSON

Journal article  |  1990  |  Archives of Virology

NEUTRALIZING MONOCLONAL-ANTIBODIES AGAINST 3 SEROTYPES OF PORCINE ROTAVIRUS

HS NAGESHA, LE BROWN, IH HOLMES

Journal article  |  1989  |  Journal of Virology

CLASS-II-RESTRICTED T-CELL CLONES TO A SYNTHETIC PEPTIDE OF INFLUENZA-VIRUS HEMAGGLUTININ DIFFER IN THEIR FINE SPECIFICITIES AND IN THE ABILITY TO RESPOND TO VIRUS

RA FFRENCH, XL TANG, EM ANDERS, DC JACKSON, DO WHITE, H DRUMMER, JD WADE, GW TREGEAR, LE BROWN

Journal article  |  1989  |  Journal of Virology

GENETIC-CONTROL AND FINE SPECIFICITY OF THE IMMUNE-RESPONSE TO A SYNTHETIC PEPTIDE OF INFLUENZA-VIRUS HEMAGGLUTININ

LE BROWN, JM MURRAY, EM ANDERS, XL TANG, DO WHITE, GW TREGEAR, DC JACKSON

Journal article  |  1988  |  Journal of Virology

EPITOPES OF AN INFLUENZA VIRAL PEPTIDE RECOGNIZED BY ANTIBODY AT SINGLE AMINO-ACID RESOLUTION

PG SCHOOFS, HM GEYSEN, DC JACKSON, LE BROWN, XL TANG, DO WHITE

Journal article  |  1988  |  Journal of Immunology

DISTINCT EPITOPES RECOGNIZED BY I-AD-RESTRICTED T-CELL CLONES WITHIN ANTIGENIC SITE-E ON INFLUENZA-VIRUS HEMAGGLUTININ

LE BROWN, RA FFRENCH, JM GAWLER, DC JACKSON, ML DYALLSMITH, EM ANDERS, GW TREGEAR, L DUNCAN, PA UNDERWOOD, DO WHITE

Journal article  |  1988  |  Journal of Virology

CHARACTERIZATION OF SUBTYPE-SPECIFIC AND CROSS-REACTIVE HELPER-T-CELL CLONES RECOGNIZING INFLUENZA-VIRUS HEMAGGLUTININ

LE BROWN, JM KATZ, RA FFRENCH, EM ANDERS, DO WHITE

Journal article  |  1987  |  Cellular Immunology

ANTIGENIC DETERMINANTS OF INFLUENZA-VIRUS HEMAGGLUTININ .12. THE EPITOPES OF A SYNTHETIC PEPTIDE REPRESENTING THE C-TERMINUS OF HA1

DC JACKSON, XL TANG, LE BROWN, JM MURRAY, DO WHITE, GW TREGEAR

Journal article  |  1986  |  Virology

ANTIGENIC ANALYSIS OF H2 INFLUENZA-VIRUS HEMAGGLUTININ WITH MONOCLONAL-ANTIBODIES

A YAMADA, LE BROWN, RG WEBSTER

Journal article  |  1985  |  Vaccine

MURINE HELPER LYMPHOCYTE-T RESPONSE TO INFLUENZA-VIRUS - RECOGNITION OF HEMAGGLUTININ BY SUBTYPE-SPECIFIC AND CROSS-REACTIVE T-CELL CLONES

JM KATZ, LE BROWN, RA FFRENCH, DO WHITE

Journal article  |  1985  |  Vaccine

LOCATION OF ANTIGENIC SITES ON THE 3-DIMENSIONAL STRUCTURE OF THE INFLUENZA N2 VIRUS NEURAMINIDASE

GM AIR, MC ELS, LE BROWN, WG LAVER, RG WEBSTER

Journal article  |  1985  |  Virology

ANTIGENIC AND BIOLOGICAL CHARACTERIZATION OF INFLUENZA-VIRUS NEURAMINIDASE (N2) WITH MONOCLONAL-ANTIBODIES

RG WEBSTER, LE BROWN, WG LAVER

Journal article  |  1984  |  Virology

CHARACTERIZATION OF H2-INFLUENZA VIRUS HEMAGGLUTININ WITH MONOCLONAL-ANTIBODIES - INFLUENCE OF RECEPTOR SPECIFICITY

A YAMADA, LE BROWN, RG WEBSTER

Journal article  |  1984  |  Virology

CHANGES IN THE ANTIGENICITY OF THE HEMAGGLUTININ MOLECULE OF H3-LABELED INFLUENZA-VIRUS AT ACIDIC PH

RG WEBSTER, LE BROWN, DC JACKSON

Journal article  |  1983  |  Virology

HETEROGENEITY OF INFLUENZA-B VIRUSES

BL LU, RG WEBSTER, LE BROWN, K NEROME

Journal article  |  1983  |  Bulletin of the World Health Organization

ANTIGENIC VARIATION IN THE INFLUENZA-A VIRUS NON-STRUCTURAL PROTEIN, NS1

LE BROWN, VS HINSHAW, RG WEBSTER

Journal article  |  1983  |  Virology

BIOLOGICAL-ACTIVITY OF MONOCLONAL-ANTIBODIES TO OPERATIONALLY DEFINED ANTIGENIC REGIONS ON THE HEMAGGLUTININ MOLECULE OF A/SEAL MASSACHUSETTS/1/80 (H7N7) INFLUENZA-VIRUS

H KIDA, LE BROWN, RG WEBSTER

Journal article  |  1982  |  Virology

ANTIGENIC DETERMINANTS OF INFLUENZA-VIRUS HEMAGGLUTININ .9. THE CARBOHYDRATE SIDE-CHAINS FROM AN ASIAN STRAIN

LE BROWN, CW WARD, DC JACKSON

Journal article  |  1982  |  Molecular Immunology

Antigenic determinants of influenza virus haemagglutinin. VI. Antigenic characterization of the oligosaccharide sidechains form HA1 of influenza virus haemagglutinins.

DC Jackson, LE Brown, DO White

Journal article  |  1981  |  Journal of General Virology

The oligosaccharide sidechains attached to the major polypeptide, HA1 of the haemagglutinin of influenza virus were examined for a..

ANTIGENIC DETERMINANTS OF INFLUENZA-VIRUS HEMAGGLUTININ .6. ANTIGENIC CHARACTERIZATION OF THE OLIGOSACCHARIDE SIDECHAINS FROM HA1 OF INFLUENZA-VIRUS HEMAGGLUTININS

DC JACKSON, LE BROWN, DO WHITE

Journal article  |  1981  |  JOURNAL OF GENERAL VIROLOGY

ANTIGENIC DETERMINANTS OF INFLUENZA-VIRUS HEMAGGLUTININ .7. THE CARBOHYDRATE SIDE-CHAINS OF A-MEMPHIS-102-72 HEMAGGLUTININ HEAVY-CHAIN WHICH CROSS-REACT WITH HOST ANTIGEN

CW WARD, LE BROWN, JC DOWNIE, DC JACKSON

Journal article  |  1981  |  Virology

ANTIGENIC DETERMINANTS OF INFLUENZA-VIRUS HEMAGGLUTININ .5. ANTIGENICITY OF THE HA2 CHAIN

LE BROWN, TAA DOPHEIDE, CW WARD, DO WHITE, DC JACKSON

Journal article  |  1980  |  Journal of Immunology

ANTIGENIC DETERMINANTS OF INFLUENZA-VIRUS HEMAGGLUTININ .4. IMMUNOGENICITY OF FRAGMENTS ISOLATED FROM THE HEMAGGLUTININ OF A-MEMPHIS-72

DC JACKSON, LE BROWN, DO WHITE, TAA DOPHEIDE, CW WARD

Journal article  |  1979  |  Journal of Immunology