Roy Robins-Browne

Spatial-temporal and phylogenetic analyses of epidemiologic data to help understand the modes of transmission of endemic typhoid fever in Samoa.

Michael J Sikorski, Jianguo Ma, Tracy H Hazen, Sachin N Desai, Siaosi Tupua, Susana Nimarota-Brown, Michelle Sialeipata, Savitra Rambocus, Susan A Ballard, Mary Valcanis, Robert E Thomsen, Roy M Robins-Browne, Benjamin P Howden, Take K Naseri, Myron M Levine, David A Rasko

Journal article  |  2022  |  PLoS Negl Trop Dis

Salmonella enterica serovar Typhi (S. Typhi) is either widely distributed or proximally transmitted via fecally-contaminated food ..

Persistence of Rare Salmonella Typhi Genotypes Susceptible to First-Line Antibiotics in the Remote Islands of Samoa

Michael J Sikorski, Tracy H Hazen, Sachin N Desai, Susana Nimarota-Brown, Siaosi Tupua, Michelle Sialeipata, Savitra Rambocus, Danielle J Ingle, Sebastian Duchene, Susan A Ballard, Mary Valcanis, Sara Zufan, Jianguo Ma, Jason W Sahl, Mailis Maes, Gordon Dougan, Robert E Thomsen, Roy M Robins-Browne, Benjamin P Howden, Take K Naseri, et al.

Journal article  |  2022  |  MBIO

For decades, the remote island nation of Samoa (population ~200,000) has faced endemic typhoid fever despite improvements in water..

Discordance Between Diagnosis Tools for Assessing Eczema in Infants: A Challenge for Intervention Trials

Laure F Pittet, Nicole L Messina, Kaya Gardiner, Bridget Freyne, Veronica Abruzzo, Clare Morrison, Peter Vuillermin, Katrina J Allen, Anne-Louise Ponsonby, Roy Robins-Browne, Frank Shann, Katie L Flanagan, Susan Donath, Dan Casalaz, Rod Phillips, Nigel Curtis

Journal article  |  2022  |  DERMATITIS

BACKGROUND: There is no standardized definition for infant eczema, and various tools have been used across studies, precluding dir..

Bacillus Calmette-Guerin Skin Reaction Predicts Enhanced Mycobacteria-Specific T-Cell Responses in Infants A Post Hoc Analysis of a Randomized Controlled Trial

Laure F Pittet, Nora Fritschi, Marc Tebruegge, Binita Dutta, Susan Donath, Nicole L Messina, Dan Casalaz, Willem A Hanekom, Warwick J Britton, Roy Robins-Browne, Nigel Curtis, Nicole Ritz

Journal article  |  2022  |  AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

Rationale: Scar formation following bacillus Calmette-Guérin (BCG) vaccination has been associated with lower all-cause mortality;..

Hepatitis B vaccine co-administration influences the heterologous effects of neonatal BCG vaccination in a sex-differential manner

Laure F Pittet, Lianne Cox, Bridget Freyne, Susie Germano, Rhian Bonnici, Kaya Gardiner, Susan Donath, Clare L Collins, Dan Casalaz, Roy Robins-Browne, Katie L Flanagan, Nicole L Messina, Nigel Curtis

Journal article  |  2022  |  VACCINE

INTRODUCTION: Bacille Calmette-Guérin (BCG) and hepatitis B (HBV) vaccines are frequently given concomitantly at birth. Neonatal B..

Point-of-Care Ultrasound by Nonexpert Operators Demonstrates High Sensitivity and Specificity in Detecting Gallstones: Data from the Samoa Typhoid Fever Control Program.

Seth A Hoffman, Sachin N Desai, Michael J Sikorski, Glenn Fatupaito, Siaosi Tupua, Robert E Thomsen, Savitra Rambocus, Susana Nimarota-Brown, Linatupu L Punimata, Michelle Sialeipata, Chandler F Tuilagi, Jane Han, Roy M Robins-Browne, Take K Naseri, Myron M Levine

Journal article  |  2022  |  Am J Trop Med Hyg

Approximately 90% of chronic typhoid carriers with persistent Salmonella enterica serovar Typhi (S. Typhi) gallbladder infection h..

Prevention of infant eczema by neonatal bacille Calmette-Guerin vaccination: The MIS BAIR randomized controlled trial

Laure F Pittet, Nicole L Messina, Kaya Gardiner, Bridget Freyne, Veronica Abruzzo, Kate L Francis, Clare Morrison, Christel Zufferey, Peter Vuillermin, Katrina J Allen, Anne-Louise Ponsonby, Roy Robins-Browne, Frank Shann, Katie L Flanagan, Rod Phillips, Susan Donath, Dan Casalaz, Nigel Curtis

Journal article  |  2021  |  ALLERGY

BACKGROUND: Bacille Calmette-Guérin (BCG) vaccine could play a role in counteracting the rising prevalence of atopic diseases, thr..

Neonatal Bacille Calmette-Guerin Vaccination and Infections in the First Year of Life: The MIS BAIR Randomized Controlled Trial

Nicole L Messina, Laure F Pittet, Kaya Gardiner, Bridget Freyne, Kate L Francis, Christel Zufferey, Veronica Abruzzo, Clare Morrison, Katrina J Allen, Katie L Flanagan, Anne-Louise Ponsonby, Roy Robins-Browne, Frank Shann, Mike South, Peter Vuillermin, Susan Donath, Dan Casalaz, Nigel Curtis

Journal article  |  2021  |  JOURNAL OF INFECTIOUS DISEASES

BACKGROUND: Bacille Calmette-Guérin (BCG) vaccination has beneficial off-target effects that may include protecting against non-my..

Re-evaluation of a Neonatal Mouse Model of Infection With Enterotoxigenic Escherichia coli

Carla J Carroll, Dianna M Hocking, Kristy I Azzopardi, Judyta Praszkier, Vicki Bennett-Wood, Kaylani Almeida, Danielle J Ingle, Sarah L Baines, Marija Tauschek, Roy M Robins-Browne

Journal article  |  2021  |  FRONTIERS IN MICROBIOLOGY

Enterotoxigenic E. coli (ETEC) is a common cause of diarrhea in children in low- and middle-income countries, and in travelers to ..

Factors associated with typical enteropathogenic Escherichia coli infection among children < 5 years old with moderate-to-severe diarrhoea in rural western Kenya, 2008-2012

K Fagerli, R Omore, S Kim, JB Ochieng, TL Ayers, J Juma, TH Farag, D Nasrin, S Panchalingam, RM Robins-Browne, JP Nataro, KL Kotloff, MM Levine, J Oundo, MB Parsons, KF Laserson, ED Mintz, RF Breiman, CE O'Reilly

Journal article  |  2020  |  EPIDEMIOLOGY AND INFECTION

Typical enteropathogenic Escherichia coli (tEPEC) infection is a major cause of diarrhoea and contributor to mortality in children..