Roy Robins-Browne

Re-evaluation of a Neonatal Mouse Model of Infection With Enterotoxigenic Escherichia coli

Carla J Carroll, Dianna M Hocking, Kristy I Azzopardi, Judyta Praszkier, Vicki Bennett-Wood, Kaylani Almeida, Danielle J Ingle, Sarah L Baines, Marija Tauschek, Roy M Robins-Browne

Journal article  |  2021  |  Frontiers in Microbiology

Enterotoxigenic E. coli (ETEC) is a common cause of diarrhea in children in low- and middle-income countries, and in travelers to ..

Factors associated with typical enteropathogenic Escherichia coli infection among children < 5 years old with moderate-to-severe diarrhoea in rural western Kenya, 2008-2012

K Fagerli, R Omore, S Kim, JB Ochieng, TL Ayers, J Juma, TH Farag, D Nasrin, S Panchalingam, RM Robins-Browne, JP Nataro, KL Kotloff, MM Levine, J Oundo, MB Parsons, KF Laserson, ED Mintz, RF Breiman, CE O'Reilly

Journal article  |  2020  |  Epidemiology and Infection

Typical enteropathogenic Escherichia coli (tEPEC) infection is a major cause of diarrhoea and contributor to mortality in children..

Sympathetic nerves control bacterial clearance

Yugeesh R Lankadeva, Clive N May, Michael J McKinley, Melanie R Neeland, Shuai Ma, Dianna M Hocking, Roy Robins-Browne, Sammy Bedoui, David GS Farmer, Simon R Bailey, Davide Martelli, Robin M McAllen

Journal article  |  2020  |  Scientific Reports

A neural reflex mediated by the splanchnic sympathetic nerves regulates systemic inflammation in negative feedback fashion, but it..

Tenacious Endemic Typhoid Fever in Samoa

Michael J Sikorski, Sachin N Desai, Siaosi Tupua, Robert E Thomsen, Jane Han, Savitra Rambocus, Susana Nimarota-Brown, Linatupu Punimata, Salesa Tusitala, Michelle Sialeipata, Seth A Hoffman, J Kathleen Tracy, Ellen E Higginson, Sharon M Tennant, Jillian S Gauld, Daniel J Klein, Susan A Ballard, Roy M Robins-Browne, Gordon Dougan, Eric J Nilles, et al.

Journal article  |  2020  |  Clinical Infectious Diseases

BACKGROUND: Typhoid fever has been endemic on the island nation of Samoa (2016 population, 195 979) since the 1960s and has persis..

Neonatal BCG Vaccination Reduces Interferon-gamma Responsiveness to Heterologous Pathogens in Infants From a Randomized Controlled

Bridget Freyne, Nicole L Messina, Susan Donath, Susie Germano, Rhian Bonnici, Kaya Gardiner, Dan Casalaz, Roy M Robins-Browne, Mihai G Netea, Katie L Flanagan, Toby Kollmann, Nigel Curtis

Journal article  |  2020  |  Journal of Infectious Diseases

BACKGROUND: BCG vaccination has beneficial nonspecific (heterologous) effects that protect against nonmycobacterial infections. We..

Risk Factors for Carriage of Antibiotic-resistant Bacteria in Healthy Children in the Community A Systematic Review

Nicole L Messina, Deborah A Williamson, Roy Robins-Browne, Penelope A Bryant, Nigel Curtis

Journal article  |  2020  |  The Pediatric Infectious Disease Journal

BACKGROUND: In addition to health care settings, antibiotic resistance has also been increasing in the community. Healthy children..

Prior Ablation of the Splanchnic Sympathetic Nerves Increases Plasma Inflammatory Cytokine Levels and Suppresses Bacteremia in Response to Systemically Administered E. coli in Sheep

Michael McKinley, Kaylani Almeida, Sammy Bedoui, David Farmer, Dianna Hocking, Yugeesh Lankadeva, Davide Martelli, Clive May, Roy Robins-Browne, Robin McAllen

Conference Proceedings  |  2020  |  The FASEB Journal

Diarrhoeal disease and subsequent risk of death in infants and children residing in low-income and middle-income countries: analysis of the GEMS case-control study and 12-month GEMS-1A follow-on study

Myron M Levine, Dilruba Nasrin, Sozinho Acacio, Quique Bassat, Helen Powell, Sharon M Tennant, Samba O Sow, Dipika Sur, Anita KM Zaidi, Abu SG Faruque, M Jahangir Hossain, Pedro L Alonso, Robert F Breiman, Ciara E O'Reilly, Eric D Mintz, Richard Omore, John B Ochieng, Joseph O Oundo, Boubou Tamboura, Doh Sanogo, et al.

Journal article  |  2020  |  The Lancet Global Health

BACKGROUND: The Global Enteric Multicenter Study (GEMS) was a 3-year case-control study that measured the burden, aetiology, and c..

Defeating the Ministers of Death. The Compelling History of Vaccination

Roy Robins-Browne

Journal article  |  2020  |  Microbiology Australia

Study protocol for the Melbourne Infant Study: BCG for Allergy and Infection Reduction (MIS BAIR), a randomised controlled trial to determine the non-specific effects of neonatal BCG vaccination in a low-mortality setting

Nicole L Messina, Kaya Gardiner, Susan Donath, Katie Flanagan, Anne-Louise Ponsonby, Frank Shann, Roy Robins-Browne, Bridget Freyne, Veronica Abruzzo, Clare Morison, Lianne Cox, Susie Germano, Christel Zufferey, Petra Zimmermann, Katie J Allen, Peter Vuillermin, Mike South, Dan Casalaz, Nigel Curtis

Journal article  |  2019  |  BMJ Open

INTRODUCTION: BCG vaccination reduces all-cause infant mortality in high-mortality settings by more than can be attributed to prot..