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Prof

Arthur Shulkes

Honorary
Surgery - Austin Health
science & technology
life sciences & biomedicine
digestive diseases
cancer
endocrinology & metabolism
2.1 biological and endogenous factors
2 aetiology
1 underpinning research
1.1 normal biological development and functioning
Arthur Shulkes's Profile Picture
Prof

Arthur Shulkes

 
Division
Medicine, Dentistry and Health Sciences
 
Primary Interest
Role of regulatory peptides in peptic ulcer disease
Arthur Shulkes's Profile Picture
Prof

Arthur Shulkes

 
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Arthur's  Short Profile
 

Patents

Displaying the most recent patent by Arthur Shulkes.

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Method of treatment

GS BALDWIN, KJ BARNHAM, J PANNEQUIN, J TANTIONGCO, AA SHULKES, RS NORTON, S KOVAC, H HE, BP SHEHAN

October 21, 2004

1

Patents

Projects

Displaying the 10 most recent projects from 25 for Arthur Shulkes.

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BUILDING COLLABORATIVE RESEARCH WITH A PARTICULAR FOCUS ON CARDIOVASCULAR HEALTH

2013 - 2017
Completed
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ROLES FOR GASTRIN AND HYPOXIA IN COLORECTAL CANCER DEVELOPMENT

Our objective is to understand how hormones such as gastrin stimulate the development of colorectal cancer. Our preliminary data shows that ..

2014 - 2016
Completed
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Targetting the Kinase PAK1 in Colorectal Cancer

This project aims to develop a new therapy for colorectal cancer (CRC). We have already demonstrated that a molecule called PAK1 is the mast..

2013 - 2016
Completed
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Targetting proGRP as a therapeutic strategy for gastrointestinal cancers

This interdisciplinary project defines what constitutes global competencies for engineers. It focuses on building knowledge and theory about..

2013 - 2014
Completed
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Role of gastrin prohormones in the development of gastrointestinal cancers

Gastrin is a stomach hormone which increases acid secretion and the growth of the stomach and bowel. This growth promoting effect may be inv..

2011 - 2013
Completed
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Mechanisms of renin angiotensin system-regulated growth of colorectal liver metastases

2011 - 2012
Completed
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Role of the Growth Factor ProGRP in the Development of Gastrointestinal Cancers

Our objective is to determine the roles of a growth factor termed bombesin. This peptide, known as GRP in the human, is a growth factor in c..

2010 - 2012
Completed
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Gastrin, Iron and Colorectal Cancer

Our objective is to understand the biological significance of the interaction between iron and the hormone gastrin. The project's significan..

2009 - 2011
Completed
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Physiology and pathology of novel forms of progastrin

Gastrin is a stomach hormone which increases acid secretion and the growth of the stomach and bowel. This growth promoting effect may be inv..

2008 - 2011
Completed
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THE BIOLOGY OF GASTRIN-FERRIC ION COMPLEXES

2007 - 2011
Completed

25

Projects

Project Types

24

Research Grant

1

Research Contracts

Scholarly Works

Displaying the 10 most recent scholarly works from 320 for Arthur Shulkes.

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Zinc Preconditioning Provides Cytoprotection following Iodinated Contrast Media Exposure in In Vitro Models

Marlon Perera, Joseph Ischia, Damien Bolton, Arthur Shulkes, Graham S Baldwin, Oneel Patel

Journal article  |  2021  |  CONTRAST MEDIA & MOLECULAR IMAGING

METHODS: Normal human proximal renal kidney cells (HK-2) were preconditioned with either increasing doses of ZnCl2 or control. Fol..

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Experimental rat models for contrast-induced nephropathy; A comprehensive review

M Perera, J Ischia, D Bolton, A Shulkes, GS Baldwin, O Patel

Journal article  |  2020  |  Journal of Nephropathology

Contrast-induced nephropathy (CIN) is an iatrogenic disease caused by the parenteral administration of iodinated contrast media (C..

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Zinc protects the kidney against ischaemia-reperfusion injury: investigating the mechanisms of protection in wild-type and genetic-knockout murine strains

D O'Kane, J Du Plessis, A Shulkes, G Baldwin, D Bolton, J Ischia, O Patel

Conference Proceedings  |  2019  |  BJU INTERNATIONAL

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MP70-11 ZINC PRECONDITIONING PROTECTS THE KIDNEY AGAINST ISCHAEMIA-REPERFUSION INJURY

Dermot O‘Kane*, Justin Du Plessis, Graham Baldwin, Arthur Shulkes, Damien Bolton, Oneel Patel, Joseph Ischia

Journal article  |  2019  |  Journal of Urology

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Corrigendum to "Targeting HIF-1α to Prevent Renal Ischemia-Reperfusion Injury: Does It Work?".

Kapil Sethi, Kenny Rao, Arthur Shulkes, Graham Baldwin, Damien Bolton, Oneel Patel, Joseph Ischia

Journal article  |  2019  |  Int J Cell Biol

[This corrects the article DOI: 10.1155/2018/9852791.].

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Zinc preconditioning protects against renal ischaemia reperfusion injury in a preclinical sheep large animal model

Dermot O'Kane, Luke Gibson, Clive N May, Justin du Plessis, Arthur Shulkes, Graham S Baldwin, Damien Bolton, Joseph Ischia, Oneel Patel

Journal article  |  2018  |  BIOMETALS

Ischaemia-reperfusion injury (IRI) during various surgical procedures, including partial nephrectomy for kidney cancer or renal tr..

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Zinc ion dyshomeostasis increases resistance of prostate cancer cells to oxidative stress via upregulation of HIF1α.

David Wetherell, Graham S Baldwin, Arthur Shulkes, Damien Bolton, Joseph Ischia, Oneel Patel

Journal article  |  2018  |  Oncotarget

Zinc ions (Zn2+) are known to influence cell survival and proliferation. However the homeostatic regulation of Zn2+ and their role..

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Neurotensin

A Shulkes

Book Chapter  |  2018

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Publish or Perish: Perceived benefits versus unintended consequences

Arthur Shulkes

Journal article  |  2018  |  AUSTRALIAN UNIVERSITIES REVIEW

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Distribution and characterisation of CCK containing enteroendocrine cells of the mouse small and large intestine

Josiane Fakhry, Joyce Wang, Patricia Martins, Linda J Fothergill, Billie Hunne, Pierre Prieur, Arthur Shulkes, Jens F Rehfeld, Brid Callaghan, John B Furness

Journal article  |  2017  |  CELL AND TISSUE RESEARCH

There is general consensus that enteroendocrine cells, EEC, containing the enteric hormone cholecystokinin (CCK) are confined to t..

320

Scholarly Works

Keyword Analysis

Clinical Health
Clinical Sciences
Oncology and Carcinogenesis
Other Health
Biochemistry and Cell Biology
Expanding Knowledge
Immunology
Medicinal and Biomolecular Chemistry
Analytical Chemistry
Biomedical Engineering

Honours, Awards and Fellowships

2008

Equity and Staff Development Award

University of Melbourne
2008

Distinguished Research Prize of the Gastroenterological Society of Australia

Gastroenterological Society of Australia
2004

Austin Hospital Research Foundation Distinguished Scientist Award.

Austin Health
2008

Fellow of the American Gastroenterological Association

4

Awards

Credentials

Positions

Honorary

Surgery - Austin Health

Honorary

Medicine, Dentistry and Health Sciences

Member

International Regulatory Peptides Society

Member

American Physiological Society

Education

Doctor of Science

University of Melbourne

PhD

University of Melbourne

Bachelor of Science (hons)

University of Melbourne

International Linkages

University of Liverpool

United Kingdom

Columbia University College of Physicians and Surgeons

United States

Institut National de la Sante et de la Recherche Medicale

France