Arthur Shulkes

Zinc protects the kidney against ischaemia-reperfusion injury: investigating the mechanisms of protection in wild-type and genetic-knockout murine strains

D O'Kane, J Du Plessis, A Shulkes, G Baldwin, D Bolton, J Ischia, O Patel

Conference Proceedings  |  2019  |  BJU INTERNATIONAL

Corrigendum to "Targeting HIF-1α to Prevent Renal Ischemia-Reperfusion Injury: Does It Work?"

Kapil Sethi, Kenny Rao, Arthur Shulkes, Graham Baldwin, Damien Bolton, Oneel Patel, Joseph Ischia

Journal article  |  2019  |  International Journal of Cell Biology

[This corrects the article DOI: 10.1155/2018/9852791.].

Zinc preconditioning protects against renal ischaemia reperfusion injury in a preclinical sheep large animal model

Dermot O'Kane, Luke Gibson, Clive N May, Justin du Plessis, Arthur Shulkes, Graham S Baldwin, Damien Bolton, Joseph Ischia, Oneel Patel

Journal article  |  2018  |  BioMetals

Zinc ion dyshomeostasis increases resistance of prostate cancer cells to oxidative stress via upregulation of HIF1α.

David Wetherell, Graham S Baldwin, Arthur Shulkes, Damien Bolton, Joseph Ischia, Oneel Patel

Journal article  |  2018  |  Oncotarget

Zinc ions (Zn2+) are known to influence cell survival and proliferation. However the homeostatic regulation of Zn2+ and their role..

Publish or Perish: Perceived benefits versus unintended consequences

Arthur Shulkes

Journal article  |  2018  |  AUSTRALIAN UNIVERSITIES REVIEW

Distribution and characterisation of CCK containing enteroendocrine cells of the mouse small and large intestine

Josiane Fakhry, Joyce Wang, Patricia Martins, Linda J Fothergill, Billie Hunne, Pierre Prieur, Arthur Shulkes, Jens F Rehfeld, Brid Callaghan, John B Furness

Journal article  |  2017  |  Cell and Tissue Research

Protective effect of zinc preconditioning against renal ischemia reperfusion injury is dose dependent

Kenny Rao, Kapil Sethi, Joseph Ischia, Luke Gibson, Laurence Galea, Lin Xiao, Mildred Yim, Mike Chang, Nathan Papa, Damien Bolton, Arthur Shulkes, Graham S Baldwin, Oneel Patel

Journal article  |  2017  |  PLOS ONE

Progastrin: a potential predictive marker of liver metastasis in colorectal cancer

David A Westwood, Oneel Patel, Christopher Christophi, Arthur Shulkes, Graham S Baldwin

Journal article  |  2017  |  International Journal of Colorectal Disease

Zinc Ions Mediate Gastrin Expression, Proliferation, and Migration Downstream of the Cholecystokinin-2 Receptor

Mike Chang, Lin Xiao, Arthur Shulkes, Graham S Baldwin, Oneel Patel

Journal article  |  2016  |  Endocrinology

Up-regulation of stem cell markers by P21-activated kinase 1 contributes to 5-fluorouracil resistance of colorectal cancer

Nhi Huynh, Arthur Shulkes, Graham Baldwin, Hong He

Journal article  |  2016  |  Cancer Biology & Therapy

Retro-inverso forms of gastrin(5-12) are as biologically active as glycine-extended gastrin in vitro but not in vivo

Kathryn M Marshall, Marie Laval, Ioulia Sims, Arthur Shulkes, Graham S Baldwin

Journal article  |  2015  |  Peptides

Identification of binding sites for C-terminal pro-gastrin-releasing peptide (GRP)-derived peptides in renal cell carcinoma: a potential target for future therapy

Joseph Ischia, Oneel Patel, Kapil Sethi, Marianne S Nordlund, Damien Bolton, Arthur Shulkes, Graham S Baldwin

Journal article  |  2015  |  BJU International

CCK2R identifies and regulates gastric antral stem cell states and carcinogenesis

Yoku Hayakawa, Guangchun Jin, Hongshan Wang, Xiaowei Chen, Christoph B Westphalen, Samuel Asfaha, Bernhard W Renz, Hiroshi Ariyama, Zinaida A Dubeykovskaya, Yoshihiro Takemoto, Yoomi Lee, Ashlesha Muley, Yagnesh Tailor, Duan Chen, Sureshkumar Muthupalani, James G Fox, Arthur Shulkes, Daniel L Worthley, Shigeo Takaishi, Timothy C Wang

Journal article  |  2015  |  Gut

HIF1 alpha Expression under Normoxia in Prostate Cancer-Which Pathways to Target?

Weranja KB Ranasinghe, Graham S Baldwin, Damien Bolton, Arthur Shulkes, Joseph Ischia, Oneel Patel

Journal article  |  2015  |  Journal of Urology

Increased gastrin gene expression provides a physiological advantage to mice under hypoxic conditions

Marie Laval, Graham S Baldwin, Arthur Shulkes, Kathryn M Marshall

Journal article  |  2015  |  American Journal of Physiology-Gastrointestinal and Liver Physiology

Glaucarubinone inhibits colorectal cancer growth by suppression of hypoxia-inducible factor 1 alpha and beta-catenin via a p-21 activated kinase 1-dependent pathway

Huynh Nhi, John A Beutler, Arthur Shulkes, Graham S Baldwin, Hong He

Journal article  |  2015  |  Biochimica et Biophysica Acta (BBA) - Molecular Cell Research

Activation by zinc of the human gastrin gene promoter in colon cancer cells in vitro and in vivo

Kathryn M Marshall, Marie Laval, Ortis Estacio, Damien F Hudson, Paul Kalitsis, Arthur Shulkes, Graham S Baldwina, Oneel Patel

Journal article  |  2015  |  Metallomics

Neurotensin

A Shulkes

Scholarly edition  |  2014

Normoxic regulation of HIF-1α in prostate cancer.

Weranja KB Ranasinghe, Graham S Baldwin, Arthur Shulkes, Damien Bolton, Oneel Patel

Journal article  |  2014  |  Nature Reviews Urology

Demonstration and biological significance of a gastrin-P21-activated kinase 1 feedback loop in colorectal cancer cells

Nhi Huynh, Kevin H Liu, Mildred Yim, Arthur Shulkes, Graham S Baldwin, Hong He

Journal article  |  2014  |  Physiological Reports

Glaucarubinone and gemcitabine synergistically reduce pancreatic cancer growth via down-regulation of P21-activated kinases

Dannel Yeo, Huynh Nhi, John A Beutler, Christopher Christophi, Arthur Shulkes, Graham S Baldwin, Mehrdad Nikfarjam, Hong He

Journal article  |  2014  |  Cancer Letters

The effects of nonspecific HIF1 alpha inhibitors on development of castrate resistance and metastases in prostate cancer

Weranja KB Ranasinghe, Shomik Sengupta, Scott Williams, Mike Chang, Arthur Shulkes, Damien M Bolton, Graham Baldwin, Oneel Patel

Journal article  |  2014  |  Cancer Medicine

Circulating gastrin concentrations in patients at increased risk of developing colorectal carcinoma

Adrienne C Paterson, Finlay A Macrae, Cathy Pizzey, Graham S Baldwin, Arthur Shulkes

Journal article  |  2014  |  Journal of Gastroenterology and Hepatology

Expression and function of gastrin-releasing peptide (GRP) in normal and cancerous urological tissues

Joseph Ischia, Oneel Patel, Damien Bolton, Arthur Shulkes, Graham S Baldwin

Journal article  |  2014  |  BJU International

Zinc ions upregulate the hormone gastrin via an E-box motif in the proximal gastrin promoter

Lin Xiao, Suzana Kovac, Mike Chang, Arthur Shulkes, Graham S Baldwin, Oneel Patel

Journal article  |  2014  |  Journal of Molecular Endocrinology

P21-activated kinase 1 promotes colorectal cancer survival by up-regulation of hypoxia-inducible factor-1 alpha

Kevin H Liu, Huynh Nhi, Oneel Patel, Arthur Shulkes, Graham Baldwin, Hong He

Journal article  |  2013  |  Cancer Letters

Gastrin

A Shulkes, GS Baldwin

Book Chapter  |  2013

The C-terminal flanking peptide of progastrin induces gastric cell apoptosis and stimulates colonic cell division in vivo

Kathryn M Marshall, Oneel Patel, Gianni Bramante, Marie Laval, Mildred Yim, Graham S Baldwin, Arthur Shulkes

Journal article  |  2013  |  Peptides

Ketosis and appetite-mediating nutrients and hormones after weight loss

P Sumithran, LA Prendergast, E Delbridge, K Purcell, A Shulkes, A Kriketos, J Proietto

Journal article  |  2013  |  European Journal of Clinical Nutrition

Non-specific HIF1 alpha inhibitors in men receiving androgen deprivation therapy for prostate cancer

W Ranasinghe, S Sengupta, S Williams, M Chang, A Shulkes, D Bolton, G Baldwin, O Patel

Conference Proceedings  |  2013  |  BJU International

p-21-Activated kinase 1 mediates gastrin-stimulated proliferation in the colorectal mucosa via multiple signaling pathways

Huynh Nhi, Mildred Yim, Jonathan Chernoff, Arthur Shulkes, Graham S Baldwin, Hong He

Journal article  |  2013  |  American Journal of Physiology - Gastrointestinal and Liver Physiology

The Role of Hypoxia-Inducible Factor 1 alpha in Determining the Properties of Castrate-Resistant Prostate Cancers

Weranja KB Ranasinghe, Lin Xiao, Suzana Kovac, Mike Chang, Carine Michiels, Damien Bolton, Arthur Shulkes, Graham S Baldwin, Oneel Patel

Journal article  |  2013  |  PLoS One

A RETROSPECTIVE ANALYSIS OF 100 MEN WITH PROSTATE CANCER: DOES HIF1 DETERMINE CASTRATE RESISTANCE AND ITS CHARACTERISTICS?

W Ranasinghe, L Xiao, S Kovac, M Chang, A Shulkes, D Bolton, G Baldwin, O Patel

Journal article  |  2012  |  Asia Pacific Journal of Clinical Oncology

Induction of Gastrin Expression in Gastrointestinal Cells by Hypoxia or Cobalt Is Independent of Hypoxia-Inducible Factor (HIF)

Lin Xiao, Suzana Kovac, Mike Chang, Arthur Shulkes, Graham S Baldwin, Oneel Patel

Journal article  |  2012  |  Endocrinology

Gastric adenocarcinoma and proximal polyposis of the stomach (GAPPS): a new autosomal dominant syndrome

DL Worthley, KD Phillips, N Wayte, KA Schrader, S Healey, P Kaurah, A Shulkes, F Grimpen, A Clouston, D Moore, D Cullen, D Ormonde, D Mounkley, X Wen, N Lindor, F Carneiro, DG Huntsman, G Chenevix-Trench, GK Suthers

Journal article  |  2012  |  Gut

The Role of Liver Fructose-1,6-Bisphosphatase in Regulating Appetite and Adiposity

Sherley Visinoni, Nurul Fathiah Izzati Khalid, Christos N Joannides, Arthur Shulkes, Mildred Yim, Jon Whitehead, Tony Tiganis, Benjamin J Lamont, Jenny M Favaloro, Joseph Proietto, Sofianos Andrikopoulos, Barbara C Fam

Journal article  |  2012  |  Diabetes

P-21 activated kinase 1 knockdown inhibits beta-catenin signalling and blocks colorectal cancer growth

Hong He, Huynh Nhi, Kevin H Liu, Cathy Malcontenti-Wilson, Jin Zhu, Christopher Christophi, Arthur Shulkes, Graham S Baldwin

Journal article  |  2012  |  Cancer Letters

A New Biomarker That Predicts Colonic Neoplasia Outcome in Patients with Hyperplastic Colonic Polyps

Catherine Do, Claudine Bertrand, Julien Palasse, Marie-Bernadette Delisle, Arthur Shulkes, Elizabeth Cohen-Jonathan-Moyal, Audrey Ferrand, Catherine Seva

Journal article  |  2012  |  Cancer prevention research

Pro-GRP-Derived Peptides Are Expressed in Colorectal Cancer Cells and Tumors and Are Biologically Active in Vivo

Oneel Patel, Daniel Clyde, Mike Chang, Marianne S Nordlund, Rohan Steel, Bruce E Kemp, D Mark Pritchard, Arthur Shulkes, Graham S Baldwin

Journal article  |  2012  |  Endocrinology

Bismuth ions inhibit the biological activity of non-amidated gastrins in vivo

Suzana Kovac, Su-Wen Loh, Shamilah Lachal, Arthur Shulkes, Graham S Baldwin

Journal article  |  2012  |  Biochemical Pharmacology

Pro-GRP-derived peptides are expressed in colorectal cancer cells and tumors and are biologically active in vivo

O Patel, undefined Clyde, AA Shulkes, G Baldwin, undefined Chang, undefined Nordlund, undefined Steel, undefined Kemp, undefined Pritchard

Journal article  |  2012  |  Endocrinology

Long-Term Persistence of Hormonal Adaptations to Weight Loss

Priya Sumithran, Luke A Prendergast, Elizabeth Delbridge, Katrina Purcell, Arthur Shulkes, Adamandia Kriketos, Joseph Proietto

Journal article  |  2011  |  New England Journal of Medicine

Gastrin-Deficient Mice Have Disturbed Hematopoiesis in Response to Iron Deficiency

Suzana Kovac, Gregory J Anderson, Warren S Alexander, Arthur Shulkes, Graham S Baldwin

Journal article  |  2011  |  Endocrinology

In vivo analysis of mouse gastrin gene regulation in enhanced GFP-BAC transgenic mice

Shigeo Takaishi, Wataru Shibata, Hiroyuki Tomita, Guangchun Jin, Xiangdong Yang, Russell Ericksen, Zinaida Dubeykovskaya, Samuel Asfaha, Michael Quante, Kelly S Betz, Arthur Shulkes, Timothy C Wang

Journal article  |  2011  |  American Journal of Physiology - Gastrointestinal and Liver Physiology

Ferric ions inhibit proteolytic processing of progastrin

Gianni Bramante, Oneel Patel, Arthur Shulkes, Graham S Baldwin

Journal article  |  2011  |  Biochemical and Biophysical Research Communications

Long-Term Persistence of Hormonal Adaptations to Weight Loss EDITORIAL COMMENT

KP Sumithran, undefined Prendergast, EA Delbridge, K Purcell, AA Shulkes, AD Kriketos, J Proietto

Journal article  |  2011  |  New England Journal of Medicine

The C-terminal flanking peptide (CTFP) of progastrin inhibits apoptosis via a PI3-kinase-dependent pathway

Oneel Patel, Kathryn M Marshall, Gianni Bramante, Graham S Baldwin, Arthur Shulkes

Journal article  |  2010  |  Regulatory Peptides

Gastrin increases its own synthesis in gastrointestinal cancer cells via the CCK2 receptor

Suzana Kovac, Lin Xiao, Arthur Shulkes, Oneel Patel, Graham S Baldwin

Journal article  |  2010  |  FEBS Letters

Pancreatic stellate cells produce acetylcholine and may play a role in pancreatic exocrine secretion

Phoebe A Phillips, Lu Yang, Arthur Shulkes, Alain Vonlaufen, Anne Poljak, Sonia Bustamante, Alessandra Warren, Zhihong Xu, Michael Guilhaus, Romano Pirola, Minoti V Apte, Jeremy S Wilson

Journal article  |  2010  |  Proceedings of the National Academy of Sciences of the United States of America

Stimulation of proliferation in the colorectal mucosa by gastrin precursors is blocked by desferrioxamine

A Ferrand, S Lachal, G Bramante, S Kovac, A Shulkes, GS Baldwin

Journal article  |  2010  |  American Journal of Physiology - Gastrointestinal and Liver Physiology

Isolation, identification and biological activity of gastrin-releasing peptide 1-46 (oGRP(1-46)), the primary GRP gene-derived peptide product of the pregnant ovine endometrium

AS Giraud, C Dumesny, JC Whitley, LM Parker, I Jennings, B Kemp, TW Moody, V Sancho, RT Jensen, A Shulkes

Journal article  |  2010  |  Peptides

Evolution of gastrointestinal hormones: the cholecystokinin/gastrin family

Graham S Baldwin, Oneel Patel, Arthur Shulkes

Journal article  |  2010  |  Current Opinion in Endocrinology, Diabetes and Obesity

The C-terminal flanking peptide (CTFP) of progastrin inhibits apoptosis via a PI3-kinase-dependent pathway

O Patel, K Marshall, G BRAMANTE, G Baldwin, AA Shulkes

Journal article  |  2010  |  Regulatory Peptides

Inactivating cholecystokinin-2 receptor inhibits progastrin-dependent colonic crypt fission, proliferation, and colorectal cancer in mice

Guangchun Jin, Vigneshwaran Ramanathan, Michael Quante, Gwang Ho Baik, Xiangdong Yang, Sophie SW Wang, Shuiping Tu, Shanisha AK Gordon, David Mark Pritchard, Andrea Varro, Arthur Shulkes, Timothy C Wang

Journal article  |  2009  |  Journal of Clinical Investigation

Expression of gastrin precursors by CD133-positive colorectal cancer cells is crucial for tumour growth

Audrey Ferrand, Mauro S Sandrin, Arthur Shulkes, Graham S Baldwin

Journal article  |  2009  |  Biochimica et Biophysica Acta - Molecular Cell Research

Peptide processing and biology in human disease

Suzana Kovac, Arthur Shulkes, Graham S Baldwin

Journal article  |  2009  |  Current Opinion in Endocrinology, Diabetes and Obesity

Gastrin-releasing peptide: Different forms, different functions

Joseph Ischia, Oneel Patel, Arthur Shulkes, Graham S Baldwin

Journal article  |  2009  |  BioFactors: vitamins - autoregulatory substances - trace elements - growth factors

Interrelationships between circulating gastrin and iron status in mice and humans

Suzana Kovac, Kelly Smith, Gregory J Anderson, John R Burgess, Arthur Shulkes, Graham S Baldwin

Journal article  |  2008  |  American Journal of Physiology - Gastrointestinal and Liver Physiology

PAK1 interacts with beta-catenin and is required for the regulation of the beta-catenin signalling pathway by gastrins

Hong He, Arthur Shulkes, Graham S Baldwin

Journal article  |  2008  |  Biochimica et Biophysica Acta - Molecular Cell Research

Effect of weight loss and ketosis on postprandial cholecystokinin and free fatty acid concentrations

Supornpim Chearskul, Elizabeth Delbridge, Arthur Shulkes, Joseph Proietto, Adamandia Kriketos

Journal article  |  2008  |  American Journal of Clinical Nutrition

Brain neuropeptide Y and CCK and peripheral adipokine receptors: temporal response in obesity induced by palatable diet

MJ Morris, H Chen, R Watts, A Shulkes, D Cameron-Smith

Journal article  |  2008  |  International Journal of Obesity

Gastrin is not required for liver regeneration

Amra Dizdarevic, Nadia Harun, Cathy Malcontenti-Wilson, Arthur Shulkes, Christopher Christophi, Graham S Baldwin

Journal article  |  2008  |  ANZ Journal of Surgery

Gastrin-releasing peptide

O PATEL, A SHULKES, G BALDWIN

Book Chapter  |  2008

Involvement of G proteins of the Rho family in the regulation of Bcl-2-like protein expression and caspase 3 activation by Gastrins

Hong He, Mildred Yim, Kevin H Liu, Stephen C Cody, Arthur Shulkes, Graham S Baldwin

Journal article  |  2008  |  Cellular Signaling

beta-catenin/Tcf-4 inhibition after progastrin targeting reduces growth and drives differentiation of intestinal tumors

Julie Pannequin, Nathalie Delaunay, Michael Buchert, Fanny Surrel, Jean-Franqois Bourgaux, Joanne Ryan, Stephanie Boireau, Jessica Coelho, Andre Pelegrin, Pomila Singh, Arthur Shulkes, Mildred Yim, Graham S Baldwin, Christine Pignodel, Gerard Lambeau, Philippe Jay, Dominique Joubert, Frederic Hollande

Journal article  |  2007  |  Gastroenterology

Phylogenetic analysis of the sequences of gastrin-releasing peptide and its receptors: Biological implications

Graham S Baldwin, Oneel Patel, Arthur Shulkes

Journal article  |  2007  |  Regulatory Peptides

Recombinant C-terminal fragments of the gastrin-releasing peptide precursor are bioactive

Oneel Patel, Chelsea Dumesny, Arthur Shulkes, Graham S Baldwin

Journal article  |  2007  |  Cancer Letters

C-terminal fragments of the gastrin-releasing peptide precursor stimulate cell proliferation via a novel receptor

Oneel Patel, Chelsea Dumesny, Arthur Shulkes, Graham S Baldwin

Journal article  |  2007  |  Endocrinology

CCK receptors and cancer

Graham S Baldwin, Arthur Shulkes

Journal article  |  2007  |  Current Topics in Medicinal Chemistry

beta-catenin/Tcf-4 inhibition after progastrin targeting reduces growth and drives differentiation of intestinal tumors

J Pannequin, N Delaunay, M Buchert, F Surrel, JF Bourgaux, J Ryan, S Boireau, J Coelho, A Pelegrin, P Singh, AA Shulkes, ME Yim, G Baldwin, C Pignodel, G Lambeau, P Jay, D Joubert, F Hollande

Journal article  |  2007  |  Gastroenterology

Circulating gastrin is increased in hemochromatosis

Kelly A Smith, Suzana Kovac, Gregory J Anderson, Arthur Shulkes, Graham S Baldwin

Journal article  |  2006  |  FEBS Letters

Production, secretion, and biological activity of the C-terminal flanking peptide of human progastrin

Kelly A Smith, Oneel Patel, Shamilah Lachal, Ian Jennings, Bruce Kemp, John Burgess, Graham S Baldwin, Arthur Shulkes

Journal article  |  2006  |  Gastroenterology

Gastrin-releasing peptide and cancer

Oneel Patel, Arthur Shulkes, Graham S Baldwin

Journal article  |  2006  |  BBA - Reviews on Cancer

Mitogenic effects of both amidated and glycine-extended gastrin-releasing peptide in defunctioned and azoxymethane-treated rat colon in vivo

N Houli, SW Loh, AS Giraud, GS Baldwin, A Shulkes

Journal article  |  2006  |  Regulatory Peptides

An enteric signal regulates putative gastrointestinal presympathetic vasomotor neurons in rats

Daniela M Sartor, Arthur Shulkes, Anthony JM Verberne

Journal article  |  2006  |  American Journal of Physiology - Regulatory, Integrative and Comparative Physiology

Regulation of Gastric Acid Secretion

Arthur Shulkes, Graham S Baldwin, Andrew S Giraud

Book Chapter  |  2006

Synthesis, expression and biological activity of the prohormone for gastrin releasing peptide (ProGRP)

C Dumesny, O Patel, S Lachal, AS Giraud, GS Baldwin, A Shulkes

Journal article  |  2006  |  Endocrinology

Glycine-extended gastrin stimulates cell proliferation and migration through a Rho- and ROCK-dependent pathway, not a Rac/Cdc42-dependent pathway

H He, J Pannequin, JP Tantiongco, A Shulkes, GS Baldwin

Journal article  |  2005  |  American Journal of Physiology - Gastrointestinal and Liver Physiology

Signaling the junctions in gut epithelium.

Frédéric Hollande, Arthur Shulkes, Graham S Baldwin

Journal article  |  2005  |  Signal Transduction Knowledge Environment

This Perspective summarizes recent developments in our understanding of the signaling pathways involved in the regulation of epith..

The effect of lipopolysaccharide on cholecystokinin in murine plasma and tissue

TJ Weiland, S Kent, NJ Voudouris, A Shulkes

Journal article  |  2005  |  Peptides

Stimulation of proliferation and migration of a colorectal cancer cell line by amidated and glycine-extended gastrin-releasing peptide via the same receptor

O Patel, C Dumesny, AS Giraud, GS Baldwin, A Shulkes

Journal article  |  2004  |  Biochemical Pharmacology

Identity and regulation of stored and secreted progastrin-derived peptides in sheep

AC Paterson, SM Lockhart, J Baker, G Neumann, GS Baldwin, A Shulkes

Journal article  |  2004  |  Endocrinology

Biological activity and ferric ion binding of fragments of glycine-extended gastrin

H He, BP Shehan, KJ Barnham, RS Norton, A Shulkes, GS Baldwin

Journal article  |  2004  |  Biochemistry

Regulation of expression of the receptors controlling gastric acidity

S Kolivas, A Shulkes

Journal article  |  2004  |  Regulatory Peptides

Developmental expression and biological activity of gastrin-releasing peptide and its receptors in the kidney

C Dumesny, JC Whitley, GS Baldwin, AS Giraud, A Shulkes

Journal article  |  2004  |  American Journal of Physiology: Renal Physiology

PPAR alpha agonists stimulate progastrin production in human colorectal carcinoma cells

S Lachal, J Ford, A Shulkes, GS Baldwin

Journal article  |  2004  |  Regulatory Peptides

Gastrins, cholecystokinins and gastrointestinal cancer

A Aly, A Shulkes, GS Baldwin

Journal article  |  2004  |  BBA - Reviews on Cancer

Divergent roles for ferric ions in the biological activity of amidated and non-amidated gastrins

J Pannequin, JP Tantiongco, S Kovac, A Shulkes, GS Baldwin

Journal article  |  2004  |  Journal of Endocrinology

A novel effect of bismuth ions - Selective inhibition of the biological activity of glycine-extended gastrin

J Pannequin, S Kovac, JP Tantiongco, RS Norton, A Shulkes, KJ Barnham, GS Baldwin

Journal article  |  2004  |  Journal of Biological Chemistry

Encyclopedia of Gastroenterology

AA SHULKES

Scholarly edition  |  2004

Gastric cancer development in mice lacking the SHP2 binding site on the IL-6 family co-receptor gp130

LM Judd, BM Alderman, M Howlett, A Shulkes, C Dow, J Moverley, D Grail, BJ Jenkins, M Ernst, AS Giraud

Journal article  |  2004  |  Gastroenterology

Method of treatment

GS BALDWIN, KJ BARNHAM, J PANNEQUIN, J TANTIONGCO, AA SHULKES, RS NORTON, S KOVAC, H HE, BP SHEHAN

Patent  |  2004

Gastrin processing patterns: ontogeny, phylogeny and pathology

AA SHULKES

Book Chapter  |  2004

Ferric ions are essential for the biological activity of the hormone glycine-extended gastrin

J Pannequin, KJ Barnham, F Hollande, A Shulkes, RS Norton, GS Baldwin

Journal article  |  2002  |  Journal of Biological Chemistry

Isolation and characterisation of the ovine gastrin-releasing peptide gene; abundant expression in the pregnant uterus and selective expression in fetal tissues

JC Whitley, C Moore, AS Giraud, A Shulkes

Journal article  |  2002  |  Journal of Endocrinology

Preparation of biologically active recombinant human progastrin(1-80)

K McQueen, S Kovac, PK Ho, K Rorison, J Pannequin, G Neumann, A Shulkes, GS Baldwin

Journal article  |  2002  |  Journal of Protein Chemistry

Metabolism of recombinant progastrin in sheep

AC Paterson, GS Baldwin, A Shulkes

Journal article  |  2002  |  American Journal of Physiology - Endocrinology and Metabolism

Antropyloroduodenal, cholecystokinin and feeding responses to pulsatile and non-pulsatile intraduodenal lipid infusion

R Vozzo, YC Su, RJ Fraser, GA Wittert, M Horowitz, CH Malbert, A Shulkes, T Volombello, IM Chapman

Journal article  |  2002  |  Neurogastroenterology and Motility

Gastrin-somatostatin interactions: from ontogeny to pathology

AA SHULKES

Book Chapter  |  2002

Maturational and maintenance effects of testosterone on terminal axon density and neuropeptide expression in the rat vas deferens

JR Keast, RJ Gleeson, A Shulkes, MJ Morris

Journal article  |  2002  |  Neuroscience

Identification of a 70-kDa gastrin-binding protein on DLD-1 human colorectal carcinoma cells

CH Yang, J Ford, Y Karelina, A Shulkes, SD Xiao, GS Baldwin

Journal article  |  2001  |  International Journal of Biochemistry and Cell Biology

Short term infusion of glycine-extended gastrin(17) stimulates both proliferation and formation of aberrant crypt foci in rat colonic mucosa

A Aly, A Shulkes, GS Baldwin

Journal article  |  2001  |  International Journal of Cancer

Expression of receptors regulating gastric acidity in the developing sheep stomach

S Kolivas, T Volombello, A Shulkes

Journal article  |  2001  |  Regulatory Peptides

Regulatory peptides: what do they regulate?

A Shulkes, G Baldwin, A Giraud

Journal article  |  2001  |  Trends in Endocrinology and Metabolism

Biology and pathology of non-amidated gastrins

A Shulkes, G Baldwin

Journal article  |  2001  |  Scandinavian Journal of Clinical and Laboratory Investigation