Arthur Shulkes

Experimental rat models for contrast-induced nephropathy; A comprehensive review

M Perera, J Ischia, D Bolton, A Shulkes, GS Baldwin, O Patel

Journal article  |  2020  |  Journal of Nephropathology

Contrast-induced nephropathy (CIN) is an iatrogenic disease caused by the parenteral administration of iodinated contrast media (C..

Zinc protects the kidney against ischaemia-reperfusion injury: investigating the mechanisms of protection in wild-type and genetic-knockout murine strains

D O'Kane, J Du Plessis, A Shulkes, G Baldwin, D Bolton, J Ischia, O Patel

Conference Proceedings  |  2019  |  BJU INTERNATIONAL

Corrigendum to "Targeting HIF-1α to Prevent Renal Ischemia-Reperfusion Injury: Does It Work?"

Kapil Sethi, Kenny Rao, Arthur Shulkes, Graham Baldwin, Damien Bolton, Oneel Patel, Joseph Ischia

Journal article  |  2019  |  Int J Cell Biol

[This corrects the article DOI: 10.1155/2018/9852791.].

Zinc preconditioning protects against renal ischaemia reperfusion injury in a preclinical sheep large animal model

Dermot O'Kane, Luke Gibson, Clive N May, Justin du Plessis, Arthur Shulkes, Graham S Baldwin, Damien Bolton, Joseph Ischia, Oneel Patel

Journal article  |  2018  |  BIOMETALS

Ischaemia-reperfusion injury (IRI) during various surgical procedures, including partial nephrectomy for kidney cancer or renal tr..

Zinc ion dyshomeostasis increases resistance of prostate cancer cells to oxidative stress via upregulation of HIF1α.

David Wetherell, Graham S Baldwin, Arthur Shulkes, Damien Bolton, Joseph Ischia, Oneel Patel

Journal article  |  2018  |  Oncotarget

Zinc ions (Zn2+) are known to influence cell survival and proliferation. However the homeostatic regulation of Zn2+ and their role..

Publish or Perish: Perceived benefits versus unintended consequences

Arthur Shulkes

Journal article  |  2018  |  AUSTRALIAN UNIVERSITIES REVIEW

Distribution and characterisation of CCK containing enteroendocrine cells of the mouse small and large intestine

Josiane Fakhry, Joyce Wang, Patricia Martins, Linda J Fothergill, Billie Hunne, Pierre Prieur, Arthur Shulkes, Jens F Rehfeld, Brid Callaghan, John B Furness

Journal article  |  2017  |  CELL AND TISSUE RESEARCH

There is general consensus that enteroendocrine cells, EEC, containing the enteric hormone cholecystokinin (CCK) are confined to t..

Protective effect of zinc preconditioning against renal ischemia reperfusion injury is dose dependent

Kenny Rao, Kapil Sethi, Joseph Ischia, Luke Gibson, Laurence Galea, Lin Xiao, Mildred Yim, Mike Chang, Nathan Papa, Damien Bolton, Arthur Shulkes, Graham S Baldwin, Oneel Patel

Journal article  |  2017  |  PLOS ONE

OBJECTIVES: Ischemia-reperfusion injury (IRI) is a major cause of acute kidney injury and chronic kidney disease. Two promising pr..

Progastrin: a potential predictive marker of liver metastasis in colorectal cancer

David A Westwood, Oneel Patel, Christopher Christophi, Arthur Shulkes, Graham S Baldwin

Journal article  |  2017  |  INTERNATIONAL JOURNAL OF COLORECTAL DISEASE

BACKGROUND AND AIMS: Staging of colorectal cancer often fails to discriminate outcomes of patients with morphologically similar tu..

Zinc Ions Mediate Gastrin Expression, Proliferation, and Migration Downstream of the Cholecystokinin-2 Receptor

Mike Chang, Lin Xiao, Arthur Shulkes, Graham S Baldwin, Oneel Patel

Journal article  |  2016  |  ENDOCRINOLOGY

Gastrin, acting via the cholecystokinin-2 receptor (CCK2R), activates its own promoter in a positive-feed-forward loop that may re..