Mark Hargreaves

Exercise adaptations: molecular mechanisms and potential targets for therapeutic benefit

Sean L McGee, Mark Hargreaves

Journal article  |  2020  |  Nature Reviews Endocrinology

Exercise is fundamental for good health, whereas physical inactivity underpins many chronic diseases of modern society. It is well..

Epigenetics and Exercise

Sean L McGee, Mark Hargreaves

Journal article  |  2019  |  Trends in Endocrinology & Metabolism

Epigenetics can be defined as 'the structural adaptation of chromosomal regions so as to register, signal, or perpetuate altered a..

Exercise serum increases GLUT4 in human adipocytes

Marcelo Flores-Opazo, Arthe Raajendiran, Matthew J Watt, Mark Hargreaves

Journal article  |  2019  |  Experimental Physiology

Exercise and GLUT4 in human subcutaneous adipose tissue

Marcelo Flores-Opazo, Eva Boland, Andrew Garnham, Robyn M Murphy, Sean L McGee, Mark Hargreaves

Journal article  |  2018  |  Physiological Reports

No evidence of direct association between GLUT4 and glycogen in human skeletal muscle

Robyn M Murphy, Marcelo Flores-Opazo, Barnaby P Frankish, Andrew Garnham, David Stapleton, Mark Hargreaves

Journal article  |  2018  |  Physiological Reports

Exercise Metabolism: Fuels for the Fire

Mark Hargreaves, Lawrence L Spriet

Journal article  |  2018  |  Cold Spring Harbor Perspectives in Medicine

Scriptaid enhances skeletal muscle insulin action and cardiac function in obese mice

Vidhi Gaur, Timothy Connor, Kylie Venardos, Darren C Henstridge, Sheree D Martin, Courtney Swinton, Shona Morrison, Kathryn Aston-Mourney, Stefan M Gehrig, Roelof van Ewijk, Gordon S Lynch, Mark A Febbraio, Gregory R Steinberg, Mark Hargreaves, Ken R Walder, Sean L McGee

Journal article  |  2017  |  Diabetes, Obesity and Metabolism

An evaluation of physical activity training in Australian medical school curricula

Abigail Strong, Mark Stoutenberg, Anita Hobson-Powell, Mark Hargreaves, Halle Beeler, Emmanuel Stamatakis

Journal article  |  2017  |  Journal of Science and Medicine in Sport

Disruption of the Class IIa HDAC Corepressor Complex Increases Energy Expenditure and Lipid Oxidation

Vidhi Gaur, Timothy Connor, Andrew Sanigorski, Sheree D Martin, Clinton R Bruce, Darren C Henstridge, Simon T Bond, Kevin A McEwen, Lyndal Kerr-Bayles, Trent D Ashton, Cassandra Fleming, Min Wu, Lisa S Pike Winer, Denise Chen, Gregg M Hudson, John WR Schwabe, Keith Baar, Mark A Febbraio, Paul Gregorevic, Frederick M Pfeffer, et al.

Journal article  |  2016  |  Cell Reports

Heat shock proteins and exercise adaptations. Our knowledge thus far and the road still ahead

Darren C Henstridge, Mark A Febbraio, Mark Hargreaves

Journal article  |  2016  |  Journal of Applied Physiology

Exercise, muscle, and CHO metabolism

M Hargreaves

Journal article  |  2015  |  Scandinavian Journal of Medicine & Science in Sports

Editorial.

Robert Boushel, Mark Hargreaves, Stephen Harridge, Birgitta Essen-Gustavsson, Jan Henriksson, Peter B Raven, Jerome A Dempsey, Stephen Harridge, Erik A Richter, Niels H Secher, Jere H Mitchell, Gerrit van Hall, Eva Jansson, Inge Holm

Journal article  |  2015  |  International Journal of Equity and Innovation in Early Childhood

Exercise Metabolism: Historical Perspective

John A Hawley, Ronald J Maughan, Mark Hargreaves

Journal article  |  2015  |  Cell Metabolism

Exercise and Gene Expression

Mark Hargreaves

Book Chapter  |  2015  |  Progress in molecular biology and translational science

Integrative Biology of Exercise

John A Hawley, Mark Hargreaves, Michael J Joyner, Juleen R Zierath

Journal article  |  2014  |  Cell

Compensatory regulation of HDAC5 in muscle maintains metabolic adaptive responses and metabolism in response to energetic stress

Sean L McGee, Courtney Swinton, Shona Morrison, Vidhi Gaur, Duncan E Campbell, Sebastian B Jorgensen, Bruce E Kemp, Keith Baar, Gregory R Steinberg, M Hargreaves

Journal article  |  2014  |  The FASEB Journal

Activating HSP72 in Rodent Skeletal Muscle Increases Mitochondrial Number and Oxidative Capacity and Decreases Insulin Resistance

Darren C Henstridge, Clinton R Bruce, Brian G Drew, Kalman Tory, Attila Kolonics, Emma Estevez, Jason Chung, Nadine Watson, Timothy Gardner, Robert S Lee-Young, Timothy Connor, Matthew J Watt, Kevin Carpenter, Mark Hargreaves, Sean L McGee, Andrea L Hevener, Mark A Febbraio

Journal article  |  2014  |  Diabetes

Exercise-induced muscle glucose uptake in mice with graded, muscle-specific GLUT-4 deletion.

Kirsten F Howlett, Sofianos Andrikopoulos, Joseph Proietto, Mark Hargreaves

Journal article  |  2013  |  Physiological Reports

To investigate the importance of the glucose transporter GLUT-4 for muscle glucose uptake during exercise, transgenic mice with sk..

EXERCISE, GLUT4, AND SKELETAL MUSCLE GLUCOSE UPTAKE

Erik A Richter, Mark Hargreaves

Journal article  |  2013  |  Physiological Reviews

Effects of compression garments on recovery following intermittent exercise

Cathryn L Pruscino, Shona Halson, Mark Hargreaves

Journal article  |  2013  |  European Journal of Applied Physiology

Effect of Exercise on the Skeletal Muscle Proteome in Patients with Type 2 Diabetes

Sophie E Hussey, Carrie G Sharoff, Andrew Garnham, Zhengping Yi, Benjamin P Bowen, Lawrence J Mandarino, Mark Hargreaves

Journal article  |  2013  |  Medicine and Science in Sports and Exercise

Skeletal muscle fat metabolism after exercise in humans: influence of fat availability

Nicholas E Kimber, David Cameron-Smith, Sean L McGee, Mark Hargreaves

Journal article  |  2013  |  Journal of Applied Physiology

Histone deacetylase 5 regulates glucose uptake and insulin action in muscle cells

Suryaprakash Raichur, Song Hooi Teh, Kenji Ohwaki, Vidhi Gaur, Yun Chau Long, Mark Hargreaves, Sean L McGee, Jun Kusunoki

Journal article  |  2012  |  JOURNAL OF MOLECULAR ENDOCRINOLOGY

No conspiracy exists

Mark Hargreaves

Journal article  |  2012  |  British Medical Journal

Exercise increases skeletal muscle GLUT4 gene expression in patients with type 2 diabetes

SE Hussey, SL McGee, A Garnham, GK McConell, M Hargreaves

Journal article  |  2012  |  Diabetes Obesity & Metabolism

More than a store: regulatory roles for glycogen in skeletal muscle adaptation to exercise

Andrew Philp, Mark Hargreaves, Keith Baar

Journal article  |  2012  |  AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM

The metabolic systems: Carbohydrate metabolism

M Hargreaves

Book Chapter  |  2011

Exercise training increases adipose tissue GLUT4 expression in patients with type 2 diabetes

SE Hussey, SL McGee, A Garnham, JM Wentworth, AE Jeukendrup, M Hargreaves

Journal article  |  2011  |  Diabetes Obesity & Metabolism

Understanding multi-organ pathology from insufficient exercise

Frank W Booth, Mark Hargreaves

Journal article  |  2011  |  Journal of Applied Physiology

'Systems biology' in human exercise physiology: is it something different from integrative physiology?

Paul L Greenhaff, Mark Hargreaves

Journal article  |  2011  |  Journal of Physiology

Understanding the regulation of muscle plasticity

Keith Baar, Mark Hargreaves

Journal article  |  2011  |  Journal of Applied Physiology

Histone modifications and exercise adaptations

Sean L McGee, Mark Hargreaves

Journal article  |  2011  |  Journal of Applied Physiology

AMPK beta subunits display isoform specific affinities for carbohydrates

Ann Koay, Ben Woodcroft, Emma J Petrie, Helen Yue, Shane Emanuelle, Michael Bieri, Michael F Bailey, Mark Hargreaves, Jong-Tae Park, Kwan-Hwa Park, Stuart Ralph, Dietbert Neumann, David Stapleton, Paul R Gooley

Journal article  |  2010  |  FEBS Letters

Daily training with high carbohydrate availability increases exogenous carbohydrate oxidation during endurance cycling

Gregory R Cox, Sally A Clark, Amanda J Cox, Shona L Halson, Mark Hargreaves, John A Hawley, Nikki Jeacocke, Rodney J Snow, Wee Kian Yeo, Louise M Burke

Journal article  |  2010  |  Journal of Applied Physiology

N-Acetylcysteine infusion does not affect glucose disposal during prolonged moderate-intensity exercise in humans

Troy L Merry, Glenn D Wadley, Christos G Stathis, Andrew P Garnham, Stephen Rattigan, Mark Hargreaves, Glenn K McConell

Journal article  |  2010  |  Journal of Physiology

AMPK-mediated regulation of transcription in skeletal muscle

Sean L McGee, Mark Hargreaves

Journal article  |  2010  |  Clinical Science

Histone modifications and skeletal muscle metabolic gene expression

Sean L McGee, Mark Hargreaves

Journal article  |  2010  |  Clinical and Experimental Pharmacology and Physiology

Acute signalling responses to intense endurance training commenced with low or normal muscle glycogen

Wee Kian Yeo, Sean L McGee, Andrew L Carey, Carl D Paton, Andrew P Garnham, Mark Hargreaves, John A Hawley

Journal article  |  2010  |  Experimental Physiology

Exercise-induced histone modifications in human skeletal muscle

Sean L McGee, Erin Fairlie, Andrew P Garnham, Mark Hargreaves

Journal article  |  2009  |  Journal of Physiology

Comparative structural analyses of purified glycogen particles from rat liver, human skeletal muscle and commercial preparations

Je-Hoon Ryu, Jace Drain, Jung Hwan Kim, Sean McGee, Angus Gray-Weale, Lynne Waddington, Glendon J Parker, Mark Hargreaves, Sang-Ho Yoo, David Stapleton

Journal article  |  2009  |  International Journal of Biological Macromolecules

Exercise and Insulin - Understanding the Molecular Interactions

Mark Hargreaves

Journal article  |  2009  |  Exercise and Sport Sciences Reviews

Brief intense interval exercise activates AMPK and p38 MAPK signaling and increases the expression of PGC-1 alpha in human skeletal muscle

Martin J Gibala, Sean L Mcgee, Andrew P Garnham, Kirsten F Howlett, Rodney J Snow, Mark Hargreaves

Journal article  |  2009  |  Journal of Applied Physiology

Intravenous AICAR administration reduces hepatic glucose output and inhibits whole body lipolysis in type 2 diabetic patients

H Boon, M Bosselaar, SFE Praet, EE Blaak, WHM Saris, AJM Wagenmakers, SL Mcgee, CJ Tack, P Smits, M Hargreaves, LJC van Loon

Journal article  |  2008  |  Diabetologia

Fatigue mechanisms determining exercise performance: integrative physiology is systems biology

Mark Hargreaves

Journal article  |  2008  |  Journal of Applied Physiology

AMP-activated protein kinase regulates GLUT4 transcription by phosphorylating histone deacetylase 5

Sean L McGee, Bryce JW van denderen, Kirsten F Howlett, Janelle Mollica, Jonathan D Schertzer, Bruce E Kemp, Mark Hargreaves

Journal article  |  2008  |  Diabetes

Effect of sex differences on human MEF2 regulation during endurance exercise

Kristian Vissing, Sean L Mcgee, Carsten Roepstorff, Peter Schjerling, Mark Hargreaves, Bente Kiens

Journal article  |  2008  |  American Journal of Physiology - Endocrinology and Metabolism

AMPK and transcriptional regulation

Sean L McGee, Mark Hargreaves

Journal article  |  2008  |  Frontiers in Bioscience

Resolving fatigue mechanisms determining exercise performance: integrative physiology at its finest!

Michael J McKenna, Mark Hargreaves

Journal article  |  2008  |  Journal of Applied Physiology

Performance limitations due to substrate availability

M Hargreaves

Book Chapter  |  2008

Physiological limits to exercise performance in the heat

Mark Hargreaves

Journal article  |  2008  |  Journal of Science and Medicine in Sport

Resistance exercise and insulin regulate AS160 and interaction with 14-3-3 in human skeletal muscle

Kirsten F Howlett, Kei Sakamoto, Andrew Garnham, David Cameron-Smith, Mark Hargreaves

Journal article  |  2007  |  Diabetes

Increased insulin-stimulated Akt pSer473 and cytosolic SHP2 protein abundance in human skeletal muscle following acute exercise and short-term training

Glenn D Wadley, Nicky Konstantopoulos, Lance Macaulay, Kirsten F Howlett, Andrew Garnham, Mark Hargreaves, David Cameron-Smith

Journal article  |  2007  |  Journal of Applied Physiology

The purpose of the present study was to determine in human skeletal muscle whether a single exercise bout and 7 days of consecutiv..

Increased insulin-stimulated Akt pSer(473) and cytosolic SHP2 protein abundance in human skeletal muscle following acute exercise and short-term training

Glenn D Wadley, Nicky Konstantopoulos, Lance Macaulay, Kirsten F Howlett, Andrew Garnham, Mark Hargreaves, David Cameron-Smith

Journal article  |  2007  |  Journal of Applied Physiology

Reduced plasma free fatty acid availability during exercise: effect on gene expression

Rebecca J Tunstall, Andrew J McAinch, Mark Hargreaves, Luc JC van Loon, David Cameron-Smith

Journal article  |  2007  |  European Journal of Applied Physiology

Comments on Point : Counterpoint "Glucose phosphorylation is/is not a significant barrier to muscle glucose uptake by the working muscle"

Abram Katz

Journal article  |  2006  |  Journal of Applied Physiology

Carbohydrate ingestion does not alter skeletal muscle AMPK signaling during exercise in humans

Robert S Lee-Young, Matthew J Palmer, Kelly C Linden, Kieran LePlastrier, Benedict J Canny, Mark Hargreaves, Glenn D Wadley, Bruce E Kemp, Glenn K McConell

Journal article  |  2006  |  American Journal of Physiology - Endocrinology and Metabolism

Acute exercise and GLUT4 expression in human skeletal muscle: influence of exercise intensity

Giorgos N Kraniou, David Cameron-Smith, Mark Hargreaves

Journal article  |  2006  |  Journal of Applied Physiology

Insulin-stimulated insulin receptor substrate-2-associated phosphatidylinositol 3-kinase activity is enhanced in human skeletal muscle after exercise

Kirsten F Howlett, Kei Sakamoto, Haiyan Yu, Laurie J Goodyear, Mark Hargreaves

Journal article  |  2006  |  Metabolism: Clinical and Experimental

Reduced glycogen availability is associated with increased AMPK alpha 2 activity, nuclear AMPK alpha 2 protein abundance, and GLUT4 mRNA expression in contracting human skeletal muscle

Gregory R Steinberg, Matthew J Watt, Sean L McGee, Stanley Chan, Mark Hargreaves, Mark A Febbraio, David Stapleton, Bruce E Kemp

Journal article  |  2006  |  Applied Physiology, Nutrition and Metabolism

Exercise and skeletal muscle glucose transporter 4 expression: Molecular mechanisms

SL McGee, M Hargreaves

Journal article  |  2006  |  Clinical and Experimental Pharmacology and Physiology

Effect of exercise intensity and hypoxia on skeletal muscle AMPK signaling and substrate metabolism in humans

GD Wadley, RS Lee-Young, BJ Canny, C Wasuntarawat, ZP Chen, M Hargreaves, BE Kemp, GK McConell

Journal article  |  2006  |  American Journal of Physiology - Endocrinology and Metabolism

Exercise does not alter subcellular localization, but increases phosphorylation of insulin-signaling proteins in human skeletal muscle

C Wilson, M Hargreaves, KF Howlett

Journal article  |  2006  |  American Journal of Physiology - Endocrinology and Metabolism

Exercise increases MEF2-and GEF DNA-binding activity in human skeletal muscle

Sean L McGee, David Sparling, Ann-Louise Olson, Mark Hargreaves

Journal article  |  2006  |  FASEB Journal

Decreased PDH activation and glycogenolysis during exercise following fat adaptation with carbohydrate restoration

T Stellingwerff, LL Spriet, MJ Watt, NE Kimber, M Hargreaves, JA Hawley, LM Burke

Journal article  |  2006  |  American Journal of Physiology - Endocrinology and Metabolism

Signalling mechanisms in skeletal muscle: Role in substrate selection and muscle adaptation

John A Hawley, Mark Hargreaves, Juleen R Zierath

Book Chapter  |  2006  |  Essays in Biochemistry

Skeletal muscle carbohydrate metabolism during exercise

M Hargreaves

Book Chapter  |  2006

The Metabolic Systems: Carbohydrate Metabolism

M Hargreaves

Book Chapter  |  2006

The Metabolic Systems: Interaction of Lipid and Carbohydrate Metabolism

L Spriet, M Hargreaves

Book Chapter  |  2006

Overview of Exercise Metabolism

L Spriet, M Hargreaves

Book Chapter  |  2006

Effect of carbohydrate ingestion on exercise-induced alterations in metabolic gene expression

LJ Cluberton, SL McGee, RM Murphy, M Hargreaves

Journal article  |  2005  |  Journal of Applied Physiology

Heat stress, cytokines, and the immune response to exercise

RL Starkie, M Hargreaves, J Rolland, MA Febbraio

Journal article  |  2005  |  Brain, Behavior and Immunity

Effect of exercise on protein kinase C activity and localization in human skeletal muscle

AJ Rose, BJ Michell, BE Kemp, M Hargreaves

Journal article  |  2004  |  Journal of Physiology

Carbohydrate-electrolyte feedings and 1h time trial cycling performance

B Desbrow, S Anderson, J Barrett, E Rao, M Hargreaves

Journal article  |  2004  |  International Journal of Sport Nutrition and Exercise Metabolism

Effect of short-term training on GLUT-4 mRNA and protein expression in human skeletal muscle

GN Kraniou, D Cameron-Smith, M Hargreaves

Journal article  |  2004  |  Experimental Physiology

Altering dietary nutrient intake that reduces glycogen content leads to phosphorylation of nuclear p38 MAP kinase in human skeletal muscle: association with IL-6 gene transcription during contraction

MHS Chan, SL McGee, MJ Watt, M Hargreaves, MA Febbraio

Journal article  |  2004  |  FASEB Journal

Pyruvate dehydrogenase activation and kinase expression in human skeletal muscle during fasting

LL Spriet, RJ Tunstall, MJ Watt, KA Mehan, M Hargreaves, D Cameron-Smith

Journal article  |  2004  |  Journal of Applied Physiology

Muscle glycogen and metabolic regulation

M Hargreaves

Journal article  |  2004  |  Proceedings of the Nutrition Society

Exercise and myocyte enhancer factor 2 regulation in human skeletal muscle

SL McGee, M Hargreaves

Journal article  |  2004  |  Diabetes

Creatine supplementation increases glycogen storage but not GLUT-4 expression in human skeletal muscle

LJC van Loon, R Murphy, AM Oosterlaar, D Cameron-Smith, M Hargreaves, AJM Wagenmakers, R Snow

Journal article  |  2004  |  Clinical Science

Pre-exercise carbohydrate and fat ingestion: effects on metabolism and performance

M Hargreaves, JA Hawley, A Jeukendrup

Journal article  |  2004  |  Journal of Sports Sciences

Regulation of glucose kinetics during intense exercise in humans: Effects of alpha- and beta-adrenergic blockade

KF Howlett, MJ Watt, M Hargreaves, MA Febbraio

Journal article  |  2003  |  Metabolism

Exercise increases Ca2 -calmodulin-dependent protein kinase II activity in human skeletal muscle

AJ Rose, M Hargreaves

Journal article  |  2003  |  Journal of Physiology

Effect of exercise intensity on skeletal muscle AMPK signaling in humans

ZP Chen, TJ Stephens, S Murthy, BJ Canny, M Hargreaves, LA Witters, BE Kemp, GK McConell

Journal article  |  2003  |  Diabetes

Effect of alcohol intake on muscle glycogen storage after prolonged exercise

LM Burke, GR Collier, EM Broad, PG Davis, DT Martin, AJ Sanigorski, M Hargreaves

Journal article  |  2003  |  Journal of Applied Physiology

Exercise increases nuclear AMPK alpha(2) in human skeletal muscle

SL McGee, KF Howlett, RL Starkie, D Cameron-Smith, BE Kemp, M Hargreaves

Journal article  |  2003  |  Diabetes

A short-term, high-fat diet up-regulates lipid metabolism and gene expression in human skeletal muscles

D Cameron-Smith, LM Burke, DJ Angus, RJ Tunstall, GR Cox, A Bonen, JA Hawley, M Hargreaves

Journal article  |  2003  |  American Journal of Clinical Nutrition

Human skeletal muscle creatine transporter mRNA and protein expression in healthy, young males and females

RM Murphy, RJ Tunstall, KA Mehan, D Cameron-Smith, MJ McKenna, LL Spriet, M Hargreaves, RJ Snow

Journal article  |  2003  |  Molecular and Cellular Biochemistry

Effect of creatine ingestion on glucose tolerance and insulin sensitivity in men

JEN Newman, M Hargreaves, A Garnham, RJ Snow

Journal article  |  2003  |  Medicine and Science in Sports and Exercise

Carbohydrate ingestion reduces skeletal muscle acetylcarnitine availability but has no effect on substrate phosphorylation at the onset of exercise in man

MJ Watt, GJF Heigenhauser, T Stellingwerff, M Hargreaves, LL Spriet

Journal article  |  2002  |  Journal of Physiology

Exercise, diet, and skeletal muscle gene expression

M Hargreaves, D Cameron-Smith

Journal article  |  2002  |  Medicine and Science in Sports and Exercise

Plasma glucose kinetics during prolonged exercise in trained humans when fed carbohydrate

DJ Angus, MA Febbraio, M Hargreaves

Journal article  |  2002  |  American Journal of Physiology - Endocrinology and Metabolism

Effect of epinephrine on glucose disposal during exercise in humans: role of muscle glycogen

MJ Watt, M Hargreaves

Journal article  |  2002  |  American Journal of Physiology - Endocrinology and Metabolism

Exercise training increases lipid metabolism gene expression in human skeletal muscle

RJ Tunstall, KA Mehan, GD Wadley, GR Collier, A Bonen, M Hargreaves, D Cameron-Smith

Journal article  |  2002  |  American Journal of Physiology - Endocrinology and Metabolism

Fasting activates the gene expression of UCP3 independent of genes necessary for lipid transport and oxidation in skeletal muscle

RJ Tunstall, KA Mehan, M Hargreaves, LL Spriet, D Cameron-Smith

Journal article  |  2002  |  Biochemical and Biophysical Research Communications

Adaptations to short-term high-fat diet persist during exercise despite high carbohydrate availability

LM Burke, JA Hawley, DJ Angus, GR Cox, SA Clark, NK Cummings, B Desbrow, M Hargreaves

Journal article  |  2002  |  Medicine and Science in Sports and Exercise

A custom-built insulin resistance gene chip

K Walder, D Segal, S Chehab, G Augert, D Cameron-Smith, M Hargreaves, GR Collier

Journal article  |  2002  |  Annals of the New York Academy of Sciences

Journal of Science and Medicine in Sport: Editorial

M Hargreaves

Journal article  |  2001  |  Journal of Science and Medicine in Sport

Effect of prior exercise on glucose metabolism in trained men

AJ Rose, K Howlett, DS King, M Hargreaves

Journal article  |  2001  |  American Journal of Physiology - Endocrinology and Metabolism

Exercise increases serum Hsp72 in humans

RC Walsh, I Koukoulas, A Garnham, PL Moseley, M Hargreaves, MA Febbraio

Journal article  |  2001  |  Cell Stress and Chaperones

Adrenaline increases skeletal muscle glycogenolysis, pyruvate dehydrogenase activation and carbohydrate oxidation during moderate exercise in humans

MJ Watt, KF Howlett, MA Febbraio, LL Spriet, M Hargreaves

Journal article  |  2001  |  Journal of Physiology

Carbohydrate metabolism during exercise in females: Effect of reduced fat availability

KF Howlett, LL Spriet, M Hargreaves

Journal article  |  2001  |  Metabolism: Clinical and Experimental

Amino acids and endurance exercise

M Hargreaves, R Snow

Journal article  |  2001  |  International Journal of Sport Nutrition and Exercise Metabolism

Effect of carbohydrate ingestion on glucose kinetics during exercise in the heat

DJ Angus, MA Febbraio, D Lasini, M Hargreaves

Journal article  |  2001  |  Journal of Applied Physiology

Differential effects of exercise on insulin-signaling gene expression in human skeletal muscle

GD Wadley, RJ Tunstall, A Sanigorski, GR Collier, M Hargreaves, D Cameron-Smith

Journal article  |  2001  |  Journal of Applied Physiology

The importance of internal controls in mRNA quantification

P Schjerling

Journal article  |  2001  |  Journal of Applied Physiology

No effect of mild heat stress on the regulation of carbohydrate metabolism at the onset of exercise

PU Saunders, MJ Watt, AP Garnham, LL Spriet, M Hargreaves, MA Febbraio

Journal article  |  2001  |  Journal of Applied Physiology

Pre-exercise nutritional strategies: Effects on metabolism and performance

M Hargreaves

Journal article  |  2001  |  Canadian Journal of Applied Physiology

Effect of fat adaptation and carbohydrate restoration on metabolism and performance during prolonged cycling

LM Burke, DJ Angus, GR Cox, NK Cummings, MA Febbraio, K Gawthorn, JA Hawley, M Minehan, DT Martin, M Hargreaves

Journal article  |  2000  |  Journal of Applied Physiology

Effect of prolonged, submaximal exercise and carbohydrate ingestion on monocyte intracellular cytokine production in humans

RL Starkie, DJ Angus, J Rolland, M Hargreaves, MA Febbraio

Journal article  |  2000  |  The Journal of Physiology

Fiber type-specific expression of GLUT4 in human skeletal muscle - Influence of exercise training

JR Daugaard, JN Nielsen, S Kristiansen, JL Andersen, M Hargreaves, EA Richter

Journal article  |  2000  |  Diabetes

Effect of acute plasma volume expansion on thermoregulation and exercise performance in the heat

MJ Watt, AP Garnham, MA Febbraio, M Hargreaves

Journal article  |  2000  |  Medicine & Science in Sports & Exercise

Effect of carbohydrate ingestion on ammonia metabolism during exercise in humans

RJ Snow, MF Carey, CG Stathis, MA Febbraio, M Hargreaves

Journal article  |  2000  |  Journal of Applied Physiology

Skeletal muscle metabolism during exercise in humans

M Hargreaves

Conference Proceedings  |  2000  |  Clinical and Experimental Pharmacology and Physiology

Effects of exercise on GLUT-4 and glycogenin gene expression in human skeletal muscle

Y Kraniou, D Cameron-Smith, M Misso, G Collier, M Hargreaves

Journal article  |  2000  |  Journal of Applied Physiology

2000 pre-olympic congress chair

T Parker, M Hargreaves

Conference Proceedings  |  2000  |  Journal of Science and Medicine in Sport

Effect of carbohydrate or carbohydrate plus medium-chain triglyceride ingestion on cycling time trial performance

DJ Angus, M Hargreaves, J Dancey, MA Febbraio

Journal article  |  2000  |  Journal of Applied Physiology

Journal of Science and Medicine in Sport: Editorial

M Hargreaves

Journal article  |  1999  |  Journal of Science and Medicine in Sport

Muscle metabolism during prolonged exercise in humans: influence of carbohydrate availability

G McConell, RJ Snow, J Proietto, M Hargreaves

Journal article  |  1999  |  Journal of Applied Physiology

Acute plasma volume expansion: effect on metabolism during submaximal exercise

MJ Watt, MA Febbraio, AP Garnham, M Hargreaves

Journal article  |  1999  |  Journal of Applied Physiology

Effect of temperature on muscle metabolism during submaximal exercise in humans

RL Starkie, M Hargreaves, DL Lambert, J Proietto, MA Febbraio

Journal article  |  1999  |  Experimental Physiology

Glucose production during strenuous exercise in humans: role of epinephrine.

K Howlett, M Febbraio, M Hargreaves

Journal article  |  1999  |  American Journal of Physiology-Endocrinology and Metabolism

The increase in hepatic glucose production (HGP) that occurs during intense exercise is accompanied by a simultaneous increase in ..

Effect of short-term training on mitochondrial ATP production rate in human skeletal muscle

EC Starritt, D Angus, M Hargreaves

Journal article  |  1999  |  Journal of Applied Physiology

1997 Sir William Refshauge Lecture. Skeletal muscle glucose metabolism during exercise: implications for health and performance.

M Hargreaves

Conference Proceedings  |  1998  |  Journal of Science and Medicine in Sport

Skeletal muscle glucose uptake and metabolism are major determinants of whole body glucose metabolism in response to exercise and ..

Glycemic index - A new tool in sport nutrition?

LM Burke, GR Collier, M Hargreaves

Conference Proceedings  |  1998  |  International Journal of Sport Nutrition

Limits to exercise performance in the heat

M Hargreaves, M Febbraio

Conference Proceedings  |  1998  |  International Journal of Sports Medicine

Muscle metabolites and performance during high-intensity, intermittent exercise

M Hargreaves, MJ McKenna, DG Jenkins, SA Warmington, JL Li, RJ Snow, MA Febbraio

Journal article  |  1998  |  Journal of Applied Physiology

Effect of increased blood glucose availability on glucose kinetics during exercise

K Howlett, D Angus, J Proietto, M Hargreaves

Journal article  |  1998  |  Journal of Applied Physiology

Effect of epinephrine on muscle glycogenolysis during exercise in trained men

MA Febbraio, DL Lambert, RL Starkie, J Proietto, M Hargreaves

Journal article  |  1998  |  Journal of Applied Physiology

Influence of ingested fluid volume on physiological responses during prolonged exercise

GK McConell, CM Burge, SL Skinner, M Hargreaves

Journal article  |  1997  |  Acta Physiologica Scandinavica

Progressive increase in glucose transport and GLUT-4 in human sarcolemmal vesicles during moderate exercise.

S Kristiansen, M Hargreaves, EA Richter

Journal article  |  1997  |  American Journal of Physiology-Endocrinology and Metabolism

Muscle glucose uptake increases progressively during moderate-intensity exercise. To elucidate whether this is due to a progressiv..

Effect of muscle glycogen availability on maximal exercise performance

M Hargreaves, JP Finn, RT Withers, JA Halbert, GC Scroop, M Mackay, RJ Snow, MF Carey

Journal article  |  1997  |  European Journal of Applied Physiology

Interactions between muscle glycogen and blood glucose during exercise.

M Hargreaves

Journal article  |  1997  |  Exercise and Sport Sciences Reviews

Muscle glycogen and blood glucose are important substrates for contracting skeletal muscle during exercise. The possibility exists..

Influence of elevated muscle temperature on metabolism during intense, dynamic exercise.

MA Febbraio, MF Carey, RJ Snow, CG Stathis, M Hargreaves

Journal article  |  1996  |  American Journal of Physiology-Regulatory, Integrative and Comparative Physiology

This study examined the effects of elevated muscle temperature on muscle metabolism during exercise. Seven active but untrained me..

Effect of timing of carbohydrate ingestion on endurance exercise performance

G McConell, K Kloot, M Hargreaves

Journal article  |  1996  |  Medicine &amp Science in Sports &amp Exercise

Effect of heat stress on glucose kinetics during exercise

M Hargreaves, D Angus, K Howlett, NM Conus, M Febbraio

Journal article  |  1996  |  Journal of Applied Physiology

Preexercise glucose ingestion and glucose kinetics during exercise

N MarmyConus, S Fabris, J Proietto, M Hargreaves

Journal article  |  1996  |  Journal of Applied Physiology

Muscle glycogen storage after prolonged exercise: Effect of the frequency of carbohydrate feedings

LM Burke, GR Collier, PG Davis, PA Fricker, AJ Sanigorski, M Hargreaves

Journal article  |  1996  |  The American Journal of Clinical Nutrition

A method for measuring sarcoplasmic reticulum calcium uptake in skeletal muscle using Fura-2

SA Warmington, M Hargreaves, DA Williams

Journal article  |  1996  |  Cell Calcium

Blunting the rise in body temperature reduces muscle glycogenolysis during exercise in humans

MA Febbraio, RJ Snow, CG Stathis, M Hargreaves, MF Carey

Journal article  |  1996  |  Experimental Physiology

Carbohydrates and exercise performance.

M Hargreaves

Conference Proceedings  |  1996  |  Nutrition Reviews

Besoins en glucides et en lipides des footballeurs

M Hargreaves

Journal article  |  1996  |  Cahiers de Nutrition et de Dietetique

Skeletal muscle GLUT-4 and postexercise muscle glycogen storage in humans

M McCoy, J Proietto, M Hargreaves

Journal article  |  1996  |  Journal of Applied Physiology

Effect of fluid ingestion on muscle metabolism during prolonged exercise

M Hargreaves, P Dillo, D Angus, M Febbraio

Journal article  |  1996  |  Journal of Applied Physiology

Exercise-induced increase in glucose transport, GLUT-4, and VAMP-2 in plasma membrane from human muscle.

S Kristiansen, M Hargreaves, EA Richter

Journal article  |  1996  |  American Journal of Physiology-Endocrinology and Metabolism

A major effect of muscle contractions is an increase in sarcolemmal glucose transport. We have used a recently developed technique..

EFFECT OF COINGESTION OF FAT AND PROTEIN WITH CARBOHYDRATE FEEDINGS ON MUSCLE GLYCOGEN-STORAGE

LM BURKE, GR COLLIER, SK BEASLEY, PG DAVIS, PA PRICKER, P HEELEY, K WALDER, M HARGREAVES

Journal article  |  1995  |  Journal of Applied Physiology

INFLUENCE OF MUSCLE GLYCOGEN ON GLYCOGENOLYSIS AND GLUCOSE-UPTAKE DURING EXERCISE IN HUMANS

M HARGREAVES, G MCCONELL, J PROIETTO

Journal article  |  1995  |  Journal of Applied Physiology

EFFECT OF HEAT-STRESS ON MUSCLE ENERGY-METABOLISM DURING EXERCISE

MA FEBBRAIO, RJ SNOW, CG STATHIS, M HARGREAVES, MF CAREY

Journal article  |  1994  |  Journal of Applied Physiology

EFFECT OF DETRAINING ON GLUT-4 PROTEIN IN HUMAN SKELETAL-MUSCLE

M MCCOY, J PROIETTO, M HARGREAVES

Journal article  |  1994  |  Journal of Applied Physiology

SKELETAL-MUSCLE GLUT-4 AND GLUCOSE-UPTAKE DURING EXERCISE IN HUMANS

G MCCONELL, M MCCOY, J PROIETTO, M HARGREAVES

Journal article  |  1994  |  Journal of Applied Physiology

EFFECT OF CARBOHYDRATE INGESTION ON GLUCOSE KINETICS DURING EXERCISE

G MCCONELL, S FABRIS, J PROIETTO, M HARGREAVES

Journal article  |  1994  |  Journal of Applied Physiology

INFLUENCE OF SODIUM ON GLUCOSE BIOAVAILABILITY DURING EXERCISE

M HARGREAVES, D COSTILL, L BURKE, G MCCONELL, M FEBBRAIO

Journal article  |  1994  |  Medicine & Science in Sports & Exercise

GLUCOSE KINETICS DURING EXERCISE IN TRAINED MEN

M HARGREAVES, J PROIETTO

Journal article  |  1994  |  Acta Physiologica Scandinavica

MUSCLE METABOLISM DURING EXERCISE AND HEAT-STRESS IN TRAINED MEN - EFFECT OF ACCLIMATION

MA FEBBRAIO, RJ SNOW, M HARGREAVES, CG STATHIS, IK MARTIN, MF CAREY

Journal article  |  1994  |  Journal of Applied Physiology

Carbohydrate and lipid requirements of soccer.

M Hargreaves

Conference Proceedings  |  1994  |  Journal of Sports Sciences

Soccer involves high-intensity, intermittent exercise and places a heavy demand on the body's liver and muscle glycogen reserves. ..

HEAT-STRESS INCREASES AMMONIA ACCUMULATION DURING EXERCISE IN HUMANS

RJ SNOW, MA FEBRAIO, MF CAREY, M HARGREAVES

Journal article  |  1993  |  Experimental Physiology

CARBOHYDRATE INGESTION DURING EXERCISE - LIQUID VS SOLID FEEDINGS

WL MASON, G MCCONELL, M HARGREAVES

Journal article  |  1993  |  Medicine and Science in Sports and Exercise

MUSCLE GLYCOGEN-STORAGE AFTER PROLONGED EXERCISE - EFFECT OF THE GLYCEMIC INDEX OF CARBOHYDRATE FEEDINGS

LM BURKE, GR COLLIER, M HARGREAVES

Journal article  |  1993  |  Journal of Applied Physiology

SPRINT TRAINING INCREASES HUMAN SKELETAL-MUSCLE NA -K -ATPASE CONCENTRATION AND IMPROVES K REGULATION

MJ MCKENNA, TA SCHMIDT, M HARGREAVES, L CAMERON, SL SKINNER, K KJELDSEN

Journal article  |  1993  |  Journal of Applied Physiology

POTASSIUM AND VENTILATION DURING INCREMENTAL EXERCISE IN TRAINED AND UNTRAINED MEN

M MCCOY, M HARGREAVES

Journal article  |  1992  |  Journal of Applied Physiology

MUSCLE GLYCOGEN AND GLUCOSE-UPTAKE DURING EXERCISE IN HUMANS

M HARGREAVES, I MEREDITH, GL JENNINGS

Journal article  |  1992  |  Experimental Physiology

SPRINT TRAINING ATTENUATES PLASMA AMMONIA ACCUMULATION FOLLOWING MAXIMAL EXERCISE

RJ SNOW, MJ MCKENNA, MF CAREY, M HARGREAVES

Journal article  |  1992  |  Acta Physiologica Scandinavica

CARBOHYDRATE NUTRITION AND FATIGUE

DL COSTILL, M HARGREAVES

Journal article  |  1992  |  Sports Medicine

EFFECT OF ARM-CRANKING ON LEG BLOOD-FLOW AND NORADRENALINE SPILLOVER DURING LEG EXERCISE IN MAN

EA RICHTER, B KIENS, M HARGREAVES, M KJAER

Journal article  |  1992  |  Acta Physiologica Scandinavica

VARIABLE RESISTANCE LOADINGS IN ANAEROBIC POWER TESTING

P GASTIN, D LAWSON, M HARGREAVES, M CAREY, I FAIRWEATHER

Journal article  |  1991  |  International Journal of Sports Medicine

Influence of fatty acids on ammonia and amino acid flux from active human muscle.

TE Graham, B Kiens, M Hargreaves, EA Richter

Journal article  |  1991  |  American Journal of Physiology-Endocrinology and Metabolism

This study examined the dynamics of ammonia and amino acid exchange of human muscle during prolonged steady-state one-legged exerc..

INFLUENCE OF ACTIVE MUSCLE MASS ON GLUCOSE-HOMEOSTASIS DURING EXERCISE IN HUMANS

M KJAER, B KIENS, M HARGREAVES, EA RICHTER

Journal article  |  1991  |  Journal of Applied Physiology

EFFECT OF INCREASED PLASMA-FREE FATTY-ACID CONCENTRATIONS ON MUSCLE METABOLISM IN EXERCISING MEN

M HARGREAVES, B KIENS, EA RICHTER

Journal article  |  1991  |  Journal of Applied Physiology

Carbohydrates and exercise

Mark Hargreaves

Journal article  |  1991  |  Journal of Sports Sciences

MUSCLE BLOOD-FLOW AND MUSCLE METABOLISM DURING EXERCISE AND HEAT-STRESS

B NIELSEN, G SAVARD, EA RICHTER, M HARGREAVES, B SALTIN

Journal article  |  1990  |  Journal of Applied Physiology

Skeletal muscle carbohydrate metabolism during exercise

M Hargreaves

Journal article  |  1990  |  Australian Journal of Science and Medicine in Sport

EXERCISE TOLERANCE IN THE HEAT ON LOW AND NORMAL SALT INTAKES

M HARGREAVES, TO MORGAN, R SNOW, M GUERIN

Journal article  |  1989  |  Clinical Science

Effect of glucose polymer ingestion on energy and fluid balance during exercise

B Kingwell, MJ McKenna, ER Sandstrom, M Hargreaves

Journal article  |  1989  |  Journal of Sports Sciences

REGULATION OF SKELETAL-MUSCLE GLYCOGENOLYSIS DURING EXERCISE

M HARGREAVES, EA RICHTER

Journal article  |  1988  |  Canadian journal of sport sciences = Journal canadien des sciences du sport

EFFECT OF CARBOHYDRATE INGESTION ON EXERCISE METABOLISM

M HARGREAVES, CA BRIGGS

Journal article  |  1988  |  Journal of Applied Physiology

EFFECT OF PRE-EXERCISE CARBOHYDRATE FEEDINGS ON ENDURANCE CYCLING PERFORMANCE

M HARGREAVES, DL COSTILL, WJ FINK, DS KING, RA FIELDING

Journal article  |  1987  |  Medicine & Science in Sports & Exercise

EFFECT OF FRUCTOSE INGESTION ON MUSCLE GLYCOGEN USAGE DURING EXERCISE

M HARGREAVES, DL COSTILL, A KATZ, WJ FINK

Journal article  |  1985  |  Medicine & Science in Sports & Exercise

METABOLIC CHARACTERISTICS OF SKELETAL-MUSCLE DURING DETRAINING FROM COMPETITIVE SWIMMING

DL COSTILL, WJ FINK, M HARGREAVES, DS KING, R THOMAS, R FIELDING

Journal article  |  1985  |  Medicine & Science in Sports & Exercise

EFFECTS OF DIETARY-SODIUM ON BODY AND MUSCLE POTASSIUM CONTENT DURING HEAT ACCLIMATION

LE ARMSTRONG, DL COSTILL, WJ FINK, D BASSETT, M HARGREAVES, I NISHIBATA, DS KING

Journal article  |  1985  |  European Journal of Applied Physiology and Occupational Physiology

Effects of reduced training on muscular power in swimmers

DL Costill, DS King, R Thomas, M Hargreaves

Journal article  |  1985  |  The Physician and Sportsmedicine

EFFECT OF CARBOHYDRATE FEEDING FREQUENCIES AND DOSAGE ON MUSCLE GLYCOGEN USE DURING EXERCISE

RA FIELDING, DL COSTILL, WJ FINK, DS KING, M HARGREAVES, JE KOVALESKI

Journal article  |  1985  |  Medicine & Science in Sports & Exercise

MUSCLE METABOLISM DURING EXERCISE IN THE HEAT IN UNACCLIMATIZED AND ACCLIMATIZED HUMANS

DS KING, DL COSTILL, WJ FINK, M HARGREAVES, RA FIELDING

Journal article  |  1985  |  Journal of Applied Physiology

EFFECT OF CARBOHYDRATE FEEDINGS ON MUSCLE GLYCOGEN UTILIZATION AND EXERCISE PERFORMANCE

M HARGREAVES, DL COSTILL, A COGGAN, WJ FINK, I NISHIBATA

Journal article  |  1984  |  Medicine and Science in Sports and Exercise

MAXIMAL EXERCISE TOLERANCE AFTER INDUCED ALKALOSIS

A KATZ, DL COSTILL, DS KING, M HARGREAVES, WJ FINK

Journal article  |  1984  |  International Journal of Sports Medicine

CARDIOSELECTIVITY OF PRENALTEROL AND ISOPROTERENOL

G JENNINGS, A BOBIK, C ODDIE, M HARGREAVES, P KORNER

Journal article  |  1983  |  Clinical Pharmacology and Therapeutics

EVALUATION OF THE CO2 REBREATHING METHOD FOR THE NON-INVASIVE MEASUREMENT OF RESTING CARDIAC-OUTPUT IN MAN

M HARGREAVES, G JENNINGS

Journal article  |  1983  |  Clinical and Experimental Pharmacology and Physiology

INTERACTION OF ALPHA-METHYLDOPA WITH AUTONOMIC REFLEX TACHYCARDIA IN MAN

AJ MCLEAN, J GELMAN, M HARGREAVES, GL JENNINGS

Journal article  |  1983  |  Journal of Cardiovascular Pharmacology

CARDIOSELECTIVITY OF PRENALTEROL

G Jennings, CJ Oddie, M Hargreaves, G Jackman, A Bobik

Conference Proceedings  |  1982  |  Australian and New Zealand Journal of Medicine