Thomas Martin

G-CSF Receptor Deletion Amplifies Cortical Bone Dysfunction in Mice With STAT3 Hyperactivation in Osteocytes

Tsuyoshi Isojima, Emma C Walker, Ingrid J Poulton, Narelle E McGregor, Ian P Wicks, Jonathan H Gooi, T John Martin, Natalie A Sims

Journal article  |  2022  |  JOURNAL OF BONE AND MINERAL RESEARCH

Bone strength is determined by the structure and composition of its thickened outer shell (cortical bone), yet the mechanisms cont..

EphrinB2 in osteocytes is essential for lysosome formation and collagen arrangement

Martha Blank, Blessing Crimeen-Irwin, Mriga Dutt, Benjamin L Parker, Cameron J Nowell, T John Martin, Natalie A Sims

Journal article  |  2022  |  Bone Reports

PI3K signaling in osteocytes drives periosteal bone formation and cortical bone strength

Natalie KY Wee, Narelle E McGregor, Emma C Walker, Jonathan H Gooi, T John Martin, Wayne A Phillips, Natalie A Sims

Conference Proceedings  |  2022  |  JOURNAL OF BONE AND MINERAL RESEARCH

PTH1R Actions on Bone Using the cAMP/Protein Kinase A Pathway

T John Martin

Journal article  |  2022  |  FRONTIERS IN ENDOCRINOLOGY

After the initial signaling action of parathyroid hormone (PTH) on bone was shown to be activation of adenylyl cyclase, its target..

Parathyroid hormone-related protein in breast cancer bone metastasis.

Rachelle W Johnson, Julie Rhoades, T John Martin

Journal article  |  2022  |  Vitam Horm

Parathyroid hormone-related protein (PTHrP) was discovered as the tumor product causing the humoral hypercalcemia of malignancy. I..

Parathyroid hormone receptors in GtoPdb v.2021.3

Alessandro Bisello, Michael Chorev, Peter A Friedman, Tom Gardella, Rebecca Hills, Harald Jueppner, T John Martin, Robert A Nissenson, John Thomas Potts, Jr., Caroline Silve, Ted B Usdin, Jean-Pierre Vilardaga

Journal article  |  2021  |  IUPHAR/BPS Guide to Pharmacology CITE

The parathyroid hormone receptors (nomenclature as agreed by the NC-IUPHAR Subcommittee on Parathyroid Hormone Receptors [49]) are..

Aspects of intercellular communication in bone and implications in therapy

T John Martin

Journal article  |  2021  |  BONE

Communication processes among the cells of bone are essential for the structure and function of the organ. After it was proposed t..

Remembering Dr John D Termine September 25, 1938-June 3, 2021 IN MEMORIAM

Ernesto Canalis, Pamela Gehron Robey, Marian F Young, T John Martin

Journal article  |  2021  |  JOURNAL OF BONE AND MINERAL RESEARCH

Dmp1Cre-directed knockdown of parathyroid hormone-related protein (PTHrP) in murine decidua is associated with a life-long increase in bone mass, width, and strength in male progeny

Niloufar Ansari, Tsuyoshi Isojima, Blessing Crimeen-Irwin, Ingrid J Poulton, Narelle E McGregor, Patricia WM Ho, Mark R Forwood, Christopher S Kovacs, Evdokia Dimitriadis, Jonathan H Gooi, T John Martin, Natalie A Sims

Journal article  |  2021  |  JOURNAL OF BONE AND MINERAL RESEARCH

Parathyroid hormone-related protein (PTHrP, gene name Pthlh) is a pleiotropic regulator of tissue homeostasis. In bone, Dmp1Cre-ta..

Parathyroid hormone receptors in GtoPdb v.2021.2

Alessandro Bisello, Michael Chorev, Peter A Friedman, Tom Gardella, Rebecca Hills, Harald Jueppner, T John Martin, Robert A Nissenson, John Thomas Potts, Jr., Caroline Silve, Ted B Usdin, Jean-Pierre Vilardaga

Journal article  |  2021  |  IUPHAR/BPS Guide to Pharmacology CITE

The parathyroid hormone receptors (nomenclature as agreed by the NC-IUPHAR Subcommittee on Parathyroid Hormone Receptors [49]) are..