P. Mark Hogarth

CytoBas: Precision component-resolved diagnostics for allergy using flow cytometric staining of basophils with recombinant allergen tetramers

Craig I McKenzie, Nirupama Varese, Pei M Aui, Bruce D Wines, Philip Mark Hogarth, Francis Thien, Mark Hew, Jennifer M Rolland, Robyn E O'Hehir, Menno C van Zelm

Journal article  |  2021  |  ALLERGY

BACKGROUND: Diagnostic tests for allergy rely on detecting allergen-specific IgE. Component-resolved diagnostics incorporate multi..

Plasma ACE2 activity is persistently elevated following SARS-CoV-2 infection: implications for COVID-19 pathogenesis and consequences

Sheila K Patel, Jennifer A Juno, Wen Shi Lee, Kathleen M Wragg, P Mark Hogarth, Stephen J Kent, Louise M Burrell

Journal article  |  2021  |  EUROPEAN RESPIRATORY JOURNAL

Th2-like T Follicular Helper Cells Promote Functional Antibody Production during Plasmodium falciparum Infection

Jo-Anne Chan, Jessica R Loughland, Fabian de Labastida Rivera, Arya SheelaNair, Dean W Andrew, Nicholas L Dooley, Bruce D Wines, Fiona H Amante, Lachlan Webb, P Mark Hogarth, James S McCarthy, James G Beeson, Christian R Engwerda, Michelle J Boyle

Journal article  |  2020  |  CELL REPORTS MEDICINE

CD4+ T follicular helper cells (Tfh) are key drivers of antibody development. During Plasmodium falciparum malaria in children, th..

Rapid generation of durable B cell memory to SARS-CoV-2 spike and nucleocapsid proteins in COVID-19 and convalescence

Gemma E Hartley, Emily SJ Edwards, Pei M Aui, Nirupama Varese, Stephanie Stojanovic, James McMahon, Anton Y Peleg, Irene Boo, Heidi E Drummer, P Mark Hogarth, Robyn E O'Hehir, Menno C van Zelm

Journal article  |  2020  |  SCIENCE IMMUNOLOGY

Lasting immunity following SARS-CoV-2 infection is questioned because serum antibodies decline in convalescence. However, function..

Rapid and lasting generation of B-cell memory to SARS-CoV-2 spike and nucleocapsid proteins in COVID-19 disease and convalescence

Gemma Hartley, Emily SJ Edwards, Pei Aui, Nirupama Varese, Stephanie Stojanovic, James McMahon, Anton Peleg, Irene Boo, Heidi Drummer, Mark Hogarth, Robyn O’Hehir, Menno van Zelm

Journal article  |  2020

ABSTRACT Background Lasting immunity to SARS-CoV-2 following infection is questioned because serum antibodies decline in convalesc..

Plasma ACE2 activity is persistently elevated following SARS-CoV-2 infection: implications for COVID-19 pathogenesis and consequences

Sheila Patel, Jennifer Juno, Wen Shi Lee, Kathleen Wragg, Mark Hogarth, Stephen Kent, Louise Burrell

Journal article  |  2020

COVID-19 causes persistent endothelial inflammation, lung and cardiovascular complications. SARS-CoV-2 utilises the catalytic site..

Th2-like T-follicular helper cells promote functional antibody production during Plasmodium falciparum infection

Jo-Anne Chan, Fabian de Labastida Rivera, Jessica Loughland, Jessica Engel, Hyun Jae Lee, Arya SheelaNair, Bruce Wines, Fiona Amante, Lachlan Webb, Pamela Mukhopadhyay, Ann-Marie Patch, Mark Hogarth, James Beeson, James McCarthy, Ashraful Haque, Christian Engwerda, Michelle Boyle

Journal article  |  2020

The most advanced malaria vaccine only has approximately 30% efficacy in target populations, and avenues to improve next generatio..

Innate and Adaptive Anti-SIV Responses in Macaque Semen: Implications for Infectivity and Risk of Transmission

Karunasinee Suphaphiphat, Sibylle Bernard-Stoecklin, Celine Gommet, Benoit Delache, Nathalie Dereuddre-Bosquet, Stephen J Kent, Bruce D Wines, P Mark Hogarth, Roger Le Grand, Mariangela Cavarelli

Journal article  |  2020  |  FRONTIERS IN IMMUNOLOGY

HIV-1 infection is transmitted primarily by sexual exposure, with semen being the principal contaminated fluid. However, HIV-speci..

Epidemic thunderstorm asthma susceptibility from sensitization to ryegrass (Lolium perenne) pollen and major allergen Lol p 5

Mark Hew, Joy Lee, Nirupama Varese, Pei M Aui, Craig I McKenzie, Bruce D Wines, Heather Aumann, Jennifer M Rolland, Phillip Mark Hogarth, Menno C van Zelm, Robyn E O'Hehir

Journal article  |  2020  |  ALLERGY

Harnessing the immune system via Fc gamma R function in immune therapy: a pathway to next-gen mAbs

Alicia M Chenoweth, Bruce D Wines, Jessica C Anania, P Hogarth

Journal article  |  2020  |  IMMUNOLOGY AND CELL BIOLOGY

The human fragment crystallizable (Fc)γ receptor (R) interacts with antigen-complexed immunoglobulin (Ig)G ligands to both activat..