Fred Mendelsohn

Neuronal Angiotensin

AM Allen, EL O'Callaghan, FAO Mendelsohn, SY Chai

Book Chapter  |  2009

Many tissues, including the brain, contain all components of the renin-angiotensin system and generate angiotensin peptides indepe..

Identification and characterization of a new cognitive enhancer based on inhibition of insulin-regulated aminopeptidase

Anthony L Albiston, Craig J Morton, Hooi Ling Ng, Vi Pham, Holly R Yeatman, Siying Ye, Ruani N Fernando, Dimitri De Bundel, David B Ascher, Frederick AO Mendelsohn, Michael W Parker, Siew Yeen Chai

Journal article  |  2008  |  FASEB JOURNAL

Approximately one-quarter of people over the age of 65 are estimated to suffer some form of cognitive impairment, underscoring the..

The angiotensin IV/AT(4) receptor

SY Chai, R Fernando, G Peck, SY Ye, FAO Mendelsohn, TA Jenkins, AL Albiston

Journal article  |  2004  |  CELLULAR AND MOLECULAR LIFE SCIENCES

The angiotensin AT(4) receptor was originally defined as the specific, high-affinity binding site for the hexapeptide angiotensin ..

Oxytocinase/insulin-regulated aminopeptidase is distributed throughout the sheep, female reproductive tract and is regulated by oestrogen in the uterus

T Mustafa, SY Chai, CN May, FAO Mendelsohn, AL Albiston

Journal article  |  2004  |  REGULATORY PEPTIDES

Using [(125)I]Angiotensin IV (Ang IV) for the autoradiographic localisation of oxytocinase/insulin-regulated aminopeptidase (IRAP)..

Attenuation of scopolamine-induced learning deficits by LVV-hemorphin-7 in rats in the passive avoidance and water maze paradigms

AL Albiston, ES Pederson, P Burns, B Purcell, JW Wright, JW Harding, FA Mendelsohn, RS Weisinger, SY Chai

Journal article  |  2004  |  BEHAVIOURAL BRAIN RESEARCH

Central administration of angiotensin IV (Ang IV) analogues attenuates scopolamine-induced amnesia. Ang IV mediates its effects by..

Effect of ICV injection of AT(4) receptor ligands, NLE1-angiotensin IV and LVV-hemorphin 7, on spatial learning in rats

J Lee, AL Albiston, AM Allen, FAO Mendelsohn, SE Ping, GL Barrett, M Murphy, MJ Morris, SG McDowall, SY Chai

Journal article  |  2004  |  NEUROSCIENCE

Central administration of angiotensin IV (Ang IV) or its analogues enhance performance of rats in passive avoidance and spatial me..

Effect of fimbria-fornix lesion on I-125-angiotensin IV (Ang IV) binding in the guinea pig hippocampus

J Lee, SY Chai, MJ Morris, FAO Mendelsohn, AM Allen

Journal article  |  2003  |  BRAIN RESEARCH

Central administration of angiotensin IV (Ang IV) and its analogues facilitates memory retention and retrieval in normal animals a..

The brain renin-angiotensin system: location and physiological roles

MJ McKinley, AL Albiston, AM Allen, ML Mathai, CN May, RM McAllen, BJ Oldfield, FAO Mendelsohn, SY Chai

Journal article  |  2003  |  INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY

Angiotensinogen, the precursor molecule for angiotensins I, II and III, and the enzymes renin, angiotensin-converting enzyme (ACE)..

Angiotensin receptors: form and function and distribution

WG Thomas, FAO Mendelsohn

Journal article  |  2003  |  INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY

The peptide hormone, angiotensin II, acts primarily via type I (AT(1)) and type II (AT(2)) angiotensin receptors. Proteolytic frag..

Structure-activity study of LVV-hemorphin-7: Angiotensin AT(4) receptor ligand and inhibitor of insulin-regulated aminopeptidase

J Lee, T Mustafa, SG McDowall, FAO Mendelsohn, M Brennan, RA Lew, AL Albiston, SY Chai

Journal article  |  2003  |  JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS

The decapeptide LVV-hemorphin-7 binds with high affinity to the angiotensin IV (Ang IV) receptor (AT(4) receptor), eliciting a num..