Mauro Sandrin

Antigen-specific CD4( )CD25( ) T cells induced by locally expressed ICOS-Ig: the role of Foxp3, Perforin, Granzyme B and IL-10-an experimental study

Dale Christiansen, Effie Mouhtouris, Russell Hodgson, Vivien R Sutto, Joseph A Trapani, Francesco L Ierino, Mauro S Sandrin

Journal article  |  2019  |  TRANSPLANT INTERNATIONAL

We have previously reported that ICOS-Ig expressed locally by a PIEC xenograft induces a perigraft cellular accumulation of CD4+ C..

Antibodies, Gal and CD46: Our contribution to the field

IFC McKenzie, MS Sandrin

Book Chapter  |  2018

Depletion of p21-activated kinase 1 up-regulates the immune system of APC(Delta 14/ ) mice and inhibits intestinal tumorigenesis

Nhi Huynh, Kai Wang, Mildred Yim, Chelsea J Dumesny, Mauro S Sandrin, Graham S Baldwin, Mehrdad Nikfarjam, Hong He

Journal article  |  2017  |  BMC CANCER

BACKGROUND: P21-activated kinase 1 (PAK1) stimulates growth and metastasis of colorectal cancer (CRC) through activation of multip..

Structural glycobiology of antibody recognition in xenotransplantation and cancer immunotherapy

M Agostino, W Farrugia, MS Sandrin, AM Scott, E Yuriev, PA Ramsland

Book Chapter  |  2014

Carbohydrate antigens recognized by natural or preformed and elicited antibodies are central to transplantation/transfusion reject..

Foxp3( ) T cells in peripheral blood of renal transplant recipients and clinical correlations

Wen X Lin, Dale Christiansen, Lu L Fu, Matthew A Roberts, Mauro S Sandrin, Francesco L Ierino

Journal article  |  2012  |  NEPHROLOGY

AIM: Immunophenotype peripheral blood T cells from renal transplant recipients (RTR) using cellular markers of regulatory T cells ..

Studies on carbohydrate xenoantigens.

Dale Christiansen, Effie Mouhtouris, Paul A Ramsland, Mauro S Sandrin

Book Chapter  |  2012  |  Methods in Molecular Biology

Naturally occurring and elicited anti-carbohydrate antibodies play a major role in immune responses to xenografts. The original ob..

Operational Tolerance in Organ Transplantation Versus Tissue Engineering: Into the Future

G Alex Bishop, Alexandra F Sharland, Francesco L Ierino, Mauro S Sandrin, Bruce M Hall, Stephen I Alexander, P Toby Coates, Geoffrey W McCaughan

Journal article  |  2011  |  TRANSPLANTATION

Approaching the Promise of Operational Tolerance in Clinical Transplantation

G Alex Bishop, Francesco L Ierino, Alexandra F Sharland, Bruce M Hall, Stephen I Alexander, Mauro S Sandrin, P Toby Coates, Geoffrey W McCaughan

Journal article  |  2011  |  TRANSPLANTATION

Long-term acceptance of transplanted organs without requirement for indefinite immunosuppression remains the ultimate goal of tran..

Prolonged Xenograft Survival Induced by Inducible Costimulator-Ig Is Associated With Increased Forkhead Box P3( ) Cells

Russell Hodgson, Dale Christiansen, Andrew Ziolkowski, Effie Mouhtouris, Charmaine J Simeonovic, Francesco L Ierino, Mauro S Sandrin

Journal article  |  2011  |  TRANSPLANTATION

BACKGROUND: Blockade of the inducible costimulator (ICOS) pathway has been shown to prolong allograft survival; however, its utili..

Antibody responses to glycolipid-borne carbohydrates require CD4( ) T cells but not CD1 or NKT cells

Dale Christiansen, Hilary A Vaughan, Julie Milland, Natalie Dodge, Effie Mouhtouris, Mark J Smyth, Dale I Godfrey, Mauro S Sandrin

Journal article  |  2011  |  IMMUNOLOGY AND CELL BIOLOGY

Naturally occurring anti-carbohydrate antibodies play a major role in both the innate and adaptive immune responses. To elicit an ..