Kong Ng

New therapeutics for osteoporosis

Kong Wah Ng, T John Martin

Journal article  |  2014  |  CURRENT OPINION IN PHARMACOLOGY

Two new approaches for the treatment of osteoporosis are summarized, each having arisen out of important new discoveries in bone b..

Future Therapies of Osteoporosis

KW Ng, T John Martin

Book Chapter  |  2013

Insights into the mechanisms that govern the formation and function of osteoblasts and osteoclasts and their communication process..

Parathyromatosis following spontaneous rupture of a parathyroid adenoma: natural history and the challenge of management

I-W Sim, S Farrell, S Grodski, C Jung, KW Ng

Journal article  |  2013  |  INTERNAL MEDICINE JOURNAL

Parathyromatosis, the presence of small nodules of hyper-functioning parathyroid tissue scattered throughout the soft tissues of t..

Gender differences in presentation and outcome of nonfunctioning pituitary macroadenomas

Carmela Caputo, Tom Sutherland, Stephen Farish, Peter McNeill, Kong W Ng, Warrick J Inder

Journal article  |  2013  |  CLINICAL ENDOCRINOLOGY

OBJECTIVES: Few data exist regarding gender differences in hormonal outcomes in nonfunctioning pituitary macroadenomas (NFPMA). Th..

Potential role of odanacatib in the treatment of osteoporosis

Kong Wah Ng

Journal article  |  2012  |  CLINICAL INTERVENTIONS IN AGING

Cathepsin K is a key enzyme involved in the degradation of organic bone matrix by osteoclasts. Inhibition of bone resorption obser..

Regulation of glucose metabolism and the skeleton.

Kong Wah Ng

Journal article  |  2011  |  Clin Endocrinol (Oxf)

Complex interactions occur among adipose tissue, the central nervous system, bone and pancreas to integrate bone remodelling, gluc..

Periprosthetic Bone Remodeling Using a Triple-Taper Polished Cemented Stem in Total Hip Arthroplasty

Aaron J Buck, Michelle M Dowsey, James D Stoney, Andrew J Hardidge, Kong Wah Ng, Peter FM Choong

Journal article  |  2010  |  JOURNAL OF ARTHROPLASTY

The triple-taper cemented femoral stem was developed to promote proximal femoral and calcar loading to minimize periprosthetic bon..

Lack of Sustained Response to Teriparatide in a Patient with Adult Hypophosphatasia

Claudia Gagnon, Natalie A Sims, Steven Mumm, Sybil A McAuley, Caroline Jung, Ingrid J Poulton, Kong Wah Ng, Peter R Ebeling

Journal article  |  2010  |  JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM

INTRODUCTION: Hypophosphatasia (HPP) is a rare genetic disorder characterized by low serum alkaline phosphatase (ALP) and defectiv..

Future developments in osteoporosis therapy.

KW Ng

Journal article  |  2009  |  Endocr Metab Immune Disord Drug Targets

Anti-resorptives that prevent osteoclasts from resorbing bone are the mainstay of treatment for osteoporosis, while parathyroid ho..

Osteoclast Inhibitory Lectin, an Immune Cell Product That Is Required for Normal Bone Physiology in Vivo

Vicky Kartsogiannis, Natalie A Sims, Julian MW Quinn, Chi Ly, Mirijana Cipetic, Ingrid J Poulton, Emma C Walker, Hasnawati Saleh, Narelle E McGregor, Morgan E Wallace, Mark J Smyth, T John Martin, Hong Zhou, Kong Wah Ng, Matthew T Gillespie

Journal article  |  2008  |  JOURNAL OF BIOLOGICAL CHEMISTRY

Osteoclast inhibitory lectin (OCIL or clrb) is a member of the natural killer cell C-type lectins that have a described role mostl..