Jeffrey Zajac

Pelvic Pain in Transgender People Using Testosterone Therapy

Sav Zwickl, Laura Burchill, Alex Fang Qi Wong, Shalem Y Leemaqz, Teddy Cook, Lachlan M Angus, Kalen Eshin, Charlotte V Elder, Sonia R Grover, Jeffrey D Zajac, Ada S Cheung

Journal article  |  2023  |  LGBT HEALTH

Purpose: This descriptive study aimed to assess the characteristics of pelvic pain and explore predictive factors for pelvic pain ..

A20 controls RANK-dependent osteoclast formation and bone physiology.

Arne Martens, Pieter Hertens, Dario Priem, Vagelis Rinotas, Theodore Meletakos, Meropi Gennadi, Lisette Van Hove, Els Louagie, Julie Coudenys, Amélie De Muynck, Djoere Gaublomme, Mozes Sze, Jolanda van Hengel, Leen Catrysse, Esther Hoste, Jeffrey D Zajac, Rachel A Davey, Luc Van Hoorebeke, Tino Hochepied, Mathieu JM Bertrand, et al.

Journal article  |  2022  |  EMBO Rep

The anti-inflammatory protein A20 serves as a critical brake on NF-κB signaling and NF-κB-dependent inflammation. In humans, polym..

Calcitonin paracrine signaling controls heart fibrogenesis and arrhythmia

Lucia Moreira, Abhijit Takawale, David A Menassa, Constantinos Psarros, Neelam Mehta, Neil Evans, Marc-Antoine Gillis, Angela Lee, Patrice Naud, Mary Norris, Michele V Clarke, Patricia K Russell, Barbara Casadei, Shoumo Bhattacharya, Jeffrey D Zajac, Rachel A Davey, Martin Sirois, Rana Sayeed, George Krasopoulos, Charles Redwood, et al.

Journal article  |  2022  |  Journal of Molecular and Cellular Cardiology

Gender-affirming hormone therapy induces specific DNA methylation changes in blood

Rebecca Shepherd, Ingrid Bretherton, Ken Pang, Anna Czajko, Bowon Kim, Amanda Vlahos, Jeffrey D Zajac, Richard Saffery, Ada Cheung, Boris Novakovic, Toby Manse

Journal article  |  2022  |  CLINICAL EPIGENETICS

BACKGROUND: DNA methylation is an epigenetic mark that is influenced by underlying genetic profile, environment, and ageing. In ad..

LBODP089 Effects Of Low-dose Oral Micronised Progesterone On Sleep, Psychological Distress And Breast Development In Transgender Individuals Undergoing Feminising Hormone Therapy: A Prospective Controlled Study

Brendan J Nolan, Aviva S Frydman, Shalem Y Leemaqz, Meg Carroll, Mathis Grossmann, Jeffrey D Zajac, Ada S Cheung

Journal article  |  2022  |  Journal of the Endocrine Society

Abstract Objective The role of micronised progesterone in hormone regimens for..

Effects of oestradiol treatment on hot flushes in men undergoing androgen deprivation therapy for prostate cancer: a randomised placebo-controlled trial

Nicholas Russell, Rudolf Hoermann, Ada S Cheung, Jeffrey D Zajac, Mathis Grossmann

Journal article  |  2022  |  EUROPEAN JOURNAL OF ENDOCRINOLOGY

OBJECTIVE: Most men undergoing androgen deprivation therapy (ADT) for prostate cancer experience hot flushes. Current treatments h..

Effects of aromatase inhibitor therapy on visceral adipose tissue area and cardiometabolic health in postmenopausal women with early and locally advanced breast cancer

Yee-Ming M Cheung, Rudolf Hoermann, Karen Van, Damian Wu, Jenny Healy, Michael Chao, Shane White, Belinda Yeo, Jeffrey Zajac, Mathis Grossmann

Journal article  |  2022  |  CLINICAL ENDOCRINOLOGY

OBJECTIVE: Aromatase inhibitor (AI) therapy provides oncological benefits in postmenopausal women with oestrogen receptor-positive..

Improved metabolic parameters of people with diabetes attending an Aboriginal health service in regional Victoria

Audrey S Eer, Tracey Hearn, Sharon Atkinson-Briggs, Shannon Drake, Satpal Singh, Sandra Neoh, Felicity Pyrlis, Mariam Hachem, Jeffrey D Zajac, Luke J Burchill, Richard C O'Brien, Elif Ekinci

Journal article  |  2022  |  INTERNAL MEDICINE JOURNAL

BACKGROUND: Aboriginal and Torres Strait Islander people have higher rates of diabetes and its complications than non-Aboriginal p..

Effects of estradiol on bone in men undergoing androgen deprivation therapy: a randomized placebo-controlled trial

Nicholas Russell, Ali Ghasem-Zadeh, Rudolf Hoermann, Ada S Cheung, Jeffrey D Zajac, Cat Shore-Lorenti, Peter R Ebeling, David J Handelsman, Mathis Grossmann

Journal article  |  2022  |  EUROPEAN JOURNAL OF ENDOCRINOLOGY

OBJECTIVE: In men, many effects of testosterone (T) on the skeleton are thought to be mediated by estradiol (E2), but trial eviden..

Multicentric EBV-associated smooth muscle tumour with involvement of the pituitary gland.

Stephanie Lau, Jasmine Zhu, Alanna Tan, Mathis Grossmann, Jeffrey D Zajac, Jonathan Clark

Journal article  |  2022  |  Pathology