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Prof

Jeffrey Zajac

Chair Of Medicine - Armc
Medicine - Austin Health
spinal and bulbar muscular atrophy
fat
obesity
metabolic syndrome
type 2 diabetes
metabolism
physiology
skeletal muscle
hypertrophy
Jeffrey Zajac's Profile Picture
Prof

Jeffrey Zajac

 
Division
Medicine, Dentistry and Health Sciences
 
Primary Interest
Use of testosterone in clinical medicine
Jeffrey Zajac's Profile Picture
Prof

Jeffrey Zajac

 
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Jeffrey's  Short Profile
 

Projects

Displaying the 10 most recent projects from 26 for Jeffrey Zajac.

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BIOLOGICAL ACTIONS OF ESTRADIOL IN MEN

In men, oestrogen may be important for strong bones and maintaining a healthy weight. Men with prostate cancer are given medical castration ..

2016 - 2022
Active
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BIOLOGICAL ACTIONS OF ESTRADIOL IN MEN

In men, oestrogen may be important for strong bones and maintaining a healthy weight. Men with prostate cancer are given medical castration ..

2016 - 2022
Active
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BONE ARCHITECTURE AND GLUCOSE METABOLISM IN MEN WITH PROSTATE CANCER

Androgen deprivation therapy (ADT) is a type of hormonal treatment which is effective for prostate cancer treatment. However, ADT may cause ..

2014 - 2018
Completed
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UNDERSTANDING AND PREVENTING AVOIDABLE RE-ADMISSIONS: DEVELOPMENT OF A PATIENT CENTERED AND DISEASE SPECIFIC SCREENING TOOL

This study aims to develop a screenings tool to prevent unplanned re-admissions, based on specific patient centred and disease specific fact..

2016 - 2018
Completed
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SKYSCAN 1272 HIGH-RESOLUTION DESK-TOP X-RAY MICROTOMOGRAPH

2016 - 2017
Completed
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THE ACTIONS OF THE HORMONE, CALCITONIN, ON BONE AND CALCIUM METABOLISM.

Calcitonin is a hormone whose main action has long been regarded as the slowing down of bone breakdown, however, its importance in human phy..

2014 - 2017
Completed
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Improving the inpatient care of patients with diabetes

2014 - 2015
Completed
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Effect of androgens on muscle, bone and fat in men

Male sex hormone or androgen deficiency (AD) is a common, but under-diagnosed condition. AD decreases general well being and contributes to ..

2011 - 2014
Completed
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Effect of androgens on muscle, bone and fat in men

Male sex hormone or androgen deficiency (AD) is a common, but under-diagnosed condition. AD decreases general well being and contributes to ..

2011 - 2014
Completed
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Grant-in-aid for research in the Department of Medicine (Austin Health)

2013 - 2014
Completed

26

Projects

Project Types

19

Research Grant

4

Internal Research Grant

3

Research Contracts

Scholarly Works

Displaying the 10 most recent scholarly works from 278 for Jeffrey Zajac.

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Diabetes care for hospital patients in Australia needs repair

Jeffrey D Zajac, Sofianos Andrikopoulos

Journal article  |  2021  |  MEDICAL JOURNAL OF AUSTRALIA

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Effect of Testosterone Treatment on Bone Microarchitecture and Bone Mineral Density in Men: A 2-Year RCT

Mark Ng Tang Fui, Rudolf Hoermann, Karen Bracken, David J Handelsman, Warrick J Inder, Bronwyn GA Stuckey, Bu B Yeap, Ali Ghasem-Zadeh, Kristy P Robledo, David Jesudason, Jeffrey D Zajac, Gary A Wittert, Mathis Grossmann

Journal article  |  2021  |  JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM

CONTEXT: Testosterone treatment increases bone mineral density (BMD) in hypogonadal men. Effects on bone microarchitecture, a dete..

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Short-Term Effects of Gender-Affirming Hormone Therapy on Dysphoria and Quality of Life in Transgender Individuals: A Prospective Controlled Study

Lucas Foster Skewis, Ingrid Bretherton, Shalem Y Leemaqz, Jeffrey D Zajac, Ada S Cheung

Journal article  |  2021  |  FRONTIERS IN ENDOCRINOLOGY

Background: Gender affirming hormone therapy (GAHT), whilst considered the standard of care in clinical guidelines for the treatme..

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Genetic Depletion of Amylin/Calcitonin Receptors Improves Memory and Learning in Transgenic Alzheimer's Disease Mouse Models

Aarti Patel, Ryoichi Kimura, Wen Fu, Rania Soudy, David MacTavish, David Westaway, Jing Yang, Rachel A Davey, Jeffrey D Zajac, Jack H Jhamandas

Journal article  |  2021  |  MOLECULAR NEUROBIOLOGY

Based upon its interactions with amyloid β peptide (Aβ), the amylin receptor, a class B G protein-coupled receptor (GPCR), is a po..

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Distinct roles of androgen receptor, estrogen receptor alpha, and BCL6 in the establishment of sex-biased DNA methylation in mouse liver

Najla AlOgayil, Klara Bauermeister, Jose Hector Galvez, Varun S Venkatesh, Qinwei Kim-wee Zhuang, Matthew L Chang, Rachel A Davey, Jeffrey D Zajac, Kinuyo Ida, Akihide Kamiya, Teruko Taketo, Guillaume Bourque, Anna K Naumova

Journal article  |  2021  |  SCIENTIFIC REPORTS

Sexual dimorphism in gene regulation, including DNA methylation, is the main driver of sexual dimorphism in phenotypes. However, t..

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Prevalence of polycythaemia with different formulations of testosterone therapy in transmasculine individuals

Brendan J Nolan, Shalem Y Leemaqz, Olivia Ooi, Pauline Cundill, Nicholas Silberstein, Peter Locke, Mathis Grossmann, Jeffrey D Zajac, Ada S Cheung

Journal article  |  2021  |  INTERNAL MEDICINE JOURNAL

BACKGROUND: Masculinising hormone therapy with testosterone is used to align an individual's physical characteristics with his or ..

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Predicting all-cause unplanned readmission within 30 days of discharge using electronic medical record data: A multi-centre study

Sifat Sharmin, Johannes J Meij, Jeffrey D Zajac, Alan Rob Moodie, Andrea B Maier

Journal article  |  2021  |  INTERNATIONAL JOURNAL OF CLINICAL PRACTICE

OBJECTIVE: To develop a predictive model for identifying patients at high risk of all-cause unplanned readmission within 30 days a..

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Neuronal androgen receptor is required for activity dependent enhancement of peripheral nerve regeneration

Patricia J Ward, Rachel A Davey, Jeffrey D Zajac, Arthur W English

Journal article  |  2021  |  DEVELOPMENTAL NEUROBIOLOGY

Neuronal activity after nerve injury can enhance axon regeneration and the restoration of function. The mechanism for this enhance..

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Changes in white adipose tissue gene expression in a randomized control trial of dieting obese men with lowered serum testosterone alone or in combination with testosterone treatment

Mathis Grossmann, Mark Ng Tang Fui, Tian Nie, Rudolf Hoermann, Michele V Clarke, Ada S Cheung, Jeffrey D Zajac, Rachel A Davey

Journal article  |  2021  |  ENDOCRINE

PURPOSE: The aim of this study was to determine early weight loss-associated changes in subcutaneous abdominal white adipose tissu..

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The calcitonin receptor regulates osteocyte lacunae acidity during lactation in mice

Rachel A Davey, Michele Clarke, Suzanne B Golub, Patricia K Russell, Jeffrey D Zajac

Journal article  |  2021  |  JOURNAL OF ENDOCRINOLOGY

The physiological role of calcitonin, and its receptor, the CTR (or Calcr), has long been debated. We previously provided the firs..

278

Scholarly Works

Keyword Analysis

Clinical Sciences
Clinical Health
Oncology and Carcinogenesis
Specific Population Health (excl. Indigenous Health)
Expanding Knowledge
Health Services and Systems
Public Health (excl. Specific Population Health)
Reproductive Medicine
Cardiovascular Medicine and Haematology
Biochemistry and Cell Biology

Honours, Awards and Fellowships

2020

Officer of the Order of Australia

2015

Life Member

Endocrine Society of Australia
1984

FRACP - Fellow of the Royal Australasian College of Physicians

3

Awards

Credentials

Positions

Chair Of Medicine - Armc

Medicine - Austin Health

Member

Australian and New Zealand Bone and Mineral Society

Member

Endocrine Society (USA)

Member

American Society for Bone and Mineral Research

Education

Doctor of Philosophy

University of Melbourne

Bachelor of Medicine-Bachelor of Surgery

University of Melbourne

International Linkages

Emory University

United States of America

Columbia University

United States