Stephen Davis

Tenecteplase Treatment and Thrombus Characteristics Associated With Early Reperfusion: An EXTEND-IA TNK Trials Analysis

Vignan Yogendrakumar, Leonid Churilov, Prodipta Guha, James Beharry, Peter J Mitchell, Timothy J Kleinig, Nawaf Yassi, Vincent Thijs, Teddy Y Wu, Helen Brown, Helen M Dewey, Tissa Wijeratne, Bernard Yan, Gagan Sharma, Patricia M Desmond, Mark W Parsons, Geoffrey A Donnan, Stephen M Davis, Bruce CV Campbell

Journal article  |  2023  |  STROKE

BACKGROUND: Intracranial occlusion site, contrast permeability, and clot burden are thrombus characteristics that influence altepl..

Tenecteplase Improves Reperfusion across Time in Large Vessel Stroke.

Vignan Yogendrakumar, James Beharry, Leonid Churilov, Khairunnisa Alidin, Melissa Ugalde, Lauren Pesavento, Louise Weir, Peter J Mitchell, Timothy J Kleinig, Nawaf Yassi, Vincent Thijs, Teddy Y Wu, Darshan G Shah, Helen M Dewey, Tissa Wijeratne, Bernard Yan, Patricia M Desmond, Gagan Sharma, Mark W Parsons, Geoffrey A Donnan, et al.

Journal article  |  2023  |  Ann Neurol

OBJECTIVE: Tenecteplase improves reperfusion compared to alteplase in patients with large vessel occlusions. To determine whether ..

Tenecteplase versus alteplase for stroke thrombolysis evaluation (TASTE): A multicentre, prospective, randomized, open-label, blinded-endpoint, controlled phase III non-inferiority trial protocol

Andrew Bivard, Carlos Garcia-Esperon, Leonid Churilov, Neil Spratt, Michelle Russell, Bruce C Campbell, Philip Choi, Timothy Kleinig, Henry Ma, Hugh Markus, Carlos Molina, Chung Hsu, Chon-Haw Tsai, Atte Meretoja, Daniel Strbian, Kenneth Butcher, Teddy Wu, Stephen Davis, Geoffrey Donnan, Christopher Levi, et al.

Journal article  |  2023  |  INTERNATIONAL JOURNAL OF STROKE

RATIONALE: Alteplase is the only approved thrombolytic agent for acute stroke. An alternative plasminogen activator, tenecteplase,..

Abstract TMP2: Intravenous Thrombolysis For Ischemic Stroke With Unknown Time Of Onset: Differences Between Wake-up Stroke And Non-wake-up Subtypes: EOS

Kamogawa Naruhiko, Kaori Miwa, Masatoshi Koga, Jensen Märit, Manabu Inoue, Sohei Yoshimura, Mayumi Fukuda-Doi, Henry Ma, Peter Ringleb, Ona Wu, Lee H Schwamm, Stephen Davis, Geoffrey A Donnan, Christian P Gerloff, Götz Thomalla, Kazunori Toyoda

Journal article  |  2023  |  Stroke

Background: The unknown onset stroke can be categorized into two groups; wake-up stroke (WUS) and non-wake-up unwitnes..

Mediation of Successful Reperfusion Effect through Infarct Growth and Cerebral Edema: A Pooled, Patient-Level Analysis of EXTEND-IA Trials and SELECT Prospective Cohort

Amrou Sarraj, Deep K Pujara, Leonid Churilov, Clark W Sitton, Felix Ng, Ameer E Hassan, Michael G Abraham, Spiros L Blackburn, Gagan Sharma, Nawaf Yassi, Timothy Kleinig, Darshan Shah, Teddy Y Wu, Wondwossen G Tekle, Ronald F Budzik, William J Hicks, Nirav Vora, Randall C Edgell, Diogo Haussen, Santiago Ortega-Gutierrez, et al.

Journal article  |  2023  |  ANNALS OF NEUROLOGY

OBJECTIVE: Reperfusion therapy is highly beneficial for ischemic stroke. Reduction in both infarct growth and edema are plausible ..

Cerebral amyloid angiopathy: clinical presentations and management challenges in the Australian context

Oshi Swarup, James LL Barker, Rosie Watson, Stephen MM Davis, Bruce CV Campbell, Nawaf Yassi

Journal article  |  2023  |  INTERNAL MEDICINE JOURNAL

Cerebral amyloid angiopathy (CAA) is a disease with several clinical manifestations. It is characterised by amyloid-beta depositio..

Alteplase for Stroke With Unknown Onset Time in Chronic Kidney Disease: A Pooled Analysis of Individual Participant Data.

Kaori Miwa, Masatoshi Koga, Märit Jensen, Manabu Inoue, Sohei Yoshimura, Mayumi Fukuda-Doi, Florent Boutitie, Henry Ma, Peter A Ringleb, Ona Wu, Lee H Schwamm, Steven Warach, Werner Hacke, Stephen M Davis, Geoffrey A Donnan, Christian Gerloff, Götz Thomalla, Kazunori Toyoda, undefined Evaluation of Unknown Onset Stroke Thrombolysis Trials (EOS) Investigators

Journal article  |  2022  |  Stroke

BACKGROUND: Although chronic kidney disease (CKD) is associated with worse stroke outcomes, data regarding the influence of CKD on..

Peter F Bladin: A pioneer in stroke Obituary

Geoffrey Donnan, Stephen Davis, Christopher Bladin

Journal article  |  2022  |  INTERNATIONAL JOURNAL OF STROKE

Correlation Between Computed Tomography-Based Tissue Net Water Uptake and Volumetric Measures of Cerebral Edema After Reperfusion Therapy

Felix C Ng, Nawaf Yassi, Gagan Sharma, Scott B Brown, Mayank Goyal, Charles BLM Majoie, Tudor G Jovin, Michael D Hill, Keith W Muir, Jeffrey L Saver, Francis Guillemin, Andrew M Demchuk, Bijoy K Menon, Luis San Roman, Philip White, Aad van der Lugt, Marc Ribo, Serge Bracard, Peter J Mitchell, Stephen M Davis, et al.

Journal article  |  2022  |  STROKE

BACKGROUND: Cerebral edema after large hemispheric infarction is associated with poor functional outcome and mortality. Net water ..

Thrombectomy versus Medical Management in Mild Strokes due to Large Vessel Occlusion: Exploratory Analysis from the EXTEND-IA Trials and a Pooled International Cohort

Amrou Sarraj, Gregory W Albers, Jordi Blasco, Juan F Arenillas, Marc Ribo, Ameer E Hassan, Natalia Perez de la Ossa, Teddy Yuan-Hao Wu, Pere Cardona Portela, Michael G Abraham, Michael Chen, Laith Maali, Timothy J Kleinig, Dennis Cordato, Adam Nathan Wallace, Joanna D Schaafsma, Navdeep Sangha, Daniel P Gibson, Spiros L Blackburn, Mercedes De Lera Alfonso, et al.

Journal article  |  2022  |  ANNALS OF NEUROLOGY

OBJECTIVE: This study was undertaken to evaluate functional and safety outcomes for endovascular thrombectomy (EVT) versus medical..