Awards/Appointments: John Storey Junior Memorial Scholarship (1983); Campion-Ma-Playoust Award from the ASMR (1986); PhD scholarship through the NHF (1991); Faculty of Medicine Fellowship (1997-99).Research interests: During 2003-2009 was appointed as Senior Scientist in the Epilepsy and Neuropharmacology Laboratory (Director: Prof Terry O’Brien) in the Dept Medicine, RMH, and completed work on several projects: (1) investigation of the neurological changes associated with epileptogenesis in temporal lobe epilepsy; (2) a study of structural, functional, neurobehavioural, neurocognitive and epilepsy outcomes associated with post-traumatic brain injury (funded through the Victorian Neurotrauma Initiative, TAC); (3) investigation of GABAA/central benzodiazepine receptor expression during epileptogenesis using PET imaging with [18F]-Flumazenil (through the Centre for Molecular Imaging at the Peter MacCallum Cancer Centre; CRC for Biomedical Imaging Development); (4) a study of adverse drug reactions associated with long-term epilepsy therapies; and, (5) various collaborations involving advanced imaging and development of imaging agents (in association with the CSIRO).Current research interests: Myers has been a key player in several large platform projects. His current position involves research projects into musculoskeletal science and application of advanced imaging techniques in the study of disease onset and progression; the long-term aim to understand the disease process.
Damian Myers has worked in the biomedical sciences and medical research utilising diverse imaging techniques including microfocus X-ray imaging (MXI) and pQCT, confocal microscopy and live-cell imaging as well as combined PET/MRI imaging. These methodologies, over many years, have been utilised to complement a range of research projects within the Faculty of Medicine, Dentistry and Health Sciences at the University of Melbourne.
Specialist training: Advanced imaging through the University of British Columbia (UBC), Vancouver, Canada (3D-Microscopy of Living Cells - July 1997) and at the ‘Bone and Mineral Centre’, The Rayne Institute, University College London; Other contributions to the field of medical imaging include: Convenor of workshops for the ANZBMS (Adelaide 2002; Sydney 2004); a past-president of the Fluorescence Imaging Group of Victoria 2002-2004 (www.FIGroup.org); Member of Victorian Government Committee, the Beamline Advisory Panel for the Imaging and Medical Beamline (IMBL) of the Australian Synchrotron.Recent and current positions: From June 2010 through to the end of September 2015 (5 years) Prof Myers was the Director of Research in the Departments of Orthopaedics (StVH) and Surgery (UoM StVH). During 2016-2017 he developed and implemented an advanced unit on Medical Imaging for Victoria University, during which time he was appointed as the Director for Medical Imaging in the Australian Institute for Musculoskeletal Science (AIMSS) at Western Health. Prof Myers also coordinated and taught into a special unit called 'Biomedical Sciences: Ethics and Values'. In 2018 he was appointed in the Melbourne Medical School as Associate Professor and as a Principal Fellow in the Department of Medicine, Western Health. At the same time he was appointed as Program Director for Medical Imaging and for Basic Sciences at AIMSS in the Western Centre for Health and Research Education, Western Health.
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Translational Use Of 3d Stem Cell Cultures For The Study Of Musculoskeletal Tissue Interac..
Internal Research Grant
RAPAMYCIN AFFECTS PALMITATE-INDUCED LIPOTOXICITY IN OSTEOBLASTS BY MODULATING APOPTOSIS AN..
Treatment with an inhibitor of fatty acid synthase attenuates bone loss in ovariectomized ..
Supporting Participants Agreement Between The University Of Melbourne And The Crc For Biom..
Displaying the 15 most recent projects by Damian Myers.
Internal Research Grant
Displaying the 65 most recent scholarly works by Damian Myers.
RAPAMYCIN AFFECTS PALMITATE-INDUCED LIPOTOXICITY IN OSTEOBLASTS BY MODULATING APOPTOSIS AND AUTOPHAGY
AA Al Saedi, CG Goodman, DM Myers, GD Duque
Journal article | 2019 | Journal of Gerontology Series A: Biological Sciences and Medical Sciences
Bone marrow fat infiltration is one of the hallmarks of aging and osteoporotic bones. Marrow adipocytes produce substantial amount..
Combination of agrin and laminin increase acetylcholine receptor clustering and enhance functional neuromuscular junction formation In vitro
Bill GX Zhang, Anita F Quigley, Justin L Bourke, Cameron J Nowell, Damian E Myers, Peter FM Choong, Robert MI Kapsa
Journal article | 2016 | Developmental Neurobiology
Osteoclast formation elicited by interleukin-33 stimulation is dependent upon the type of osteoclast progenitor.
Damien G Eeles, Jason M Hodge, Preetinder P Singh, Johannes A Schuijers, Brian L Grills, Matthew T Gillespie, Damian E Myers, Julian MW Quinn
Journal article | 2015 | Molecular and Cellular Endocrinology
Osteoclasts are bone resorbing multinucleated cells (MNCs) derived from macrophage progenitors. IL-33 has been reported to drive o..
Differentiation of Stem Cells from Human Infrapatellar Fat Pad: Characterization of Cells Undergoing Chondrogenesis
Raed Felimban, Ken Ye, Kathy Traianedes, Claudia Di Bella, Jeremy Crook, Gordon G Wallace, Anita Quigley, Peter FM Choong, Damian E Myers
Journal article | 2014 | Tissue Engineering Part A
In Vivo Measurement of Hippocampal GABA(A)/cBZR Density with [F-18]-Flumazenil PET for the Study of Disease Progression in an Animal Model of Temporal Lobe Epilepsy
Lucy Vivash, Marie-Claude Gregoire, Viviane Bouilleret, Alexis Berard, Catriona Wimberley, David Binns, Peter Roselt, Andrew Katsifis, Damian E Myers, Rodney J Hicks, Terence J O'Brien, Stefanie Dedeurwaerdere
Journal article | 2014 | PLoS One
F-18-Flumazenil: A gamma-Aminobutyric Acid A-Specific PET Radiotracer for the Localization of Drug-Resistant Temporal Lobe Epilepsy
Lucy Vivash, Marie-Claude Gregoire, Eddie W Lau, Robert E Ware, David Binns, Peter Roselt, Viviane Bouilleret, Damian E Myers, Mark J Cook, Rodney J Hicks, Terence J O'Brien
Journal article | 2013 | Journal of Nuclear Medicine
Can structural or functional changes following traumatic brain injury in the rat predict epileptic outcome?
Sandy R Shultz, Lisa Cardamone, Ying R Liu, R Edward Hogan, Luigi Maccotta, David K Wright, Ping Zheng, Amelia Koe, Marie-Claude Gregoire, John P Williams, Rodney J Hicks, Nigel C Jones, Damian E Myers, Terence J O'Brien, Viviane Bouilleret
Journal article | 2013 | Epilepsia
Confounding Neurodegenerative Effects of Manganese for In Vivo MR Imaging in Rat Models of Brain Insults
Viviane Bouilleret, Lisa Cardamone, Cyril Liu, Amelia S Koe, Ke Fang, John P Williams, Damian E Myers, Terence J O'Brien, Nigel C Jones
Journal article | 2011 | Journal of Magnetic Resonance Imaging
Quantitative comparison of preparation methodologies for x-ray fluorescence microscopy of brain tissue
Simon A James, Damian E Myers, Martin D de Jonge, Stefan Vogt, Chris G Ryan, Brett A Sexton, Pamela Hoobin, David Paterson, Daryl L Howard, Sheridan C Mayo, Matteo Altissimo, Gareth F Moorhead, Stephen W Wilkins
Journal article | 2011 | Analytical and Bioanalytical Chemistry
The molecular pathogenesis of osteosarcoma: a review.
Matthew L Broadhead, Jonathan CM Clark, Damian E Myers, Crispin R Dass, Peter FM Choong
Journal article | 2011 | Sarcoma
Osteosarcoma is the most common primary malignancy of bone. It arises in bone during periods of rapid growth and primarily affects..
Progressive Metabolic and Structural Cerebral Perturbations After Traumatic Brain Injury: An In Vivo Imaging Study in the Rat
Ying R Liu, Lisa Cardamone, R Edward Hogan, Marie-Claude Gregoire, John P Williams, Rod J Hicks, David Binns, Amelia Koe, Nigel C Jones, Damian E Myers, Terence J O'Brien, Viviane Bouilleret
Journal article | 2010 | Journal of Nuclear Medicine
Proteinase-activated receptor-2 (PAR(2)) and mouse osteoblasts: Regulation of cell function and lack of specificity of PAR(2)-activating peptides
Smitha R Georgy, Charles N Pagel, David M Wong, Sutharshani Sivagurunathan, Lay H Loh, Damian E Myers, Morley D Hollenberg, Robert N Pike, Eleanor J Mackie
Journal article | 2010 | Clinical and Experimental Pharmacology and Physiology
First experiments on the Australian Synchrotron Imaging and Medical beamline, including investigations of the effective source size in respect of X-ray imaging
Andrew W Stevenson, Sheridan C Mayo, Daniel Haeusermann, Anton Maksimenko, Richard F Garrett, Christopher J Hall, Stephen W Wilkins, Robert A Lewis, Damian E Myers
Journal article | 2010 | Journal of Synchrotron Radiation
Excitotoxic-mediated transcriptional decreases in HCN2 channel function increase network excitability in CA1
Brendan EL Adams, Christopher A Reid, Damian Myers, Caroline Ng, Kim Powell, A Marie Phillips, Thomas Zheng, Terence J O'Brien, David A Williams
Journal article | 2009 | Experimental Neurology
In-vivo imaging characteristics of two fluorinated flumazenil radiotracers in the rat
Stefanie Dedeurwaerdere, Marie-Claude Gregoire, Lucy Vivash, Peter Roselt, David Binns, Christopher Fookes, Ivan Greguric, Tien Pham, Christian Loc'h, Andrew Katsifis, Rodney J Hicks, Terence J O'Brien, Damian E Myers
Journal article | 2009 | European Journal of Nuclear Medicine and Molecular Imaging
MRI-Based Large Deformation High Dimensional Mapping of the Hippocampus in Rats: Development and Validation of the Technique
R Edward Hogan, Viviane Bouilleret, Ying Rui Liu, Lei Wang, John P Williams, Bianca Jupp, Damian Myers, Terence J O'Brien
Journal article | 2009 | Journal of Magnetic Resonance Imaging
The heat shock protein 90 inhibitor, 17-allylamino-17-demethoxygeldanamycin, enhances osteoclast formation and potentiates bone metastasis of a human breast cancer cell line
JT Price, JMW Quinn, NA Sims, J Vieusseux, K Waldeck, SE Docherty, D Myers, A Nakamura, MC Waltham, MT Gillespie, EW Thompson
Journal article | 2005 | Cancer Research
Isolation of a human homolog of osteoclast inhibitory lectin that inhibits the formation and function of osteoclasts
YS Hu, H Zhou, D Myers, JMW Quinn, GJ Atkins, C Ly, C Gange, V Kartsogiannis, J Elliott, P Kostakis, ACW Zannettino, B Cromer, WJ McKinstry, DM Findlay, MT Gillespie, KW Ng
Journal article | 2004 | Journal of Bone and Mineral Research
Prevalence and nature of connexin 26 mutations in children with non-syndromic deafness
HHM Dahl, K Saunders, TM Kelly, AH Osborn, S Wilcox, B Cone-Wesson, JL Wunderlich, D Du Sart, M Kamarinos, RJM Gardner, S Dennehy, R Williamson, N Vallance, P Mutton
Journal article | 2001 | Medical Journal of Australia
Induction of osteoclasts from CD14-positive human peripheral blood mononuclear cells by receptor activator of nuclear factor kappaB ligand (RANKL).
GC Nicholson, M Malakellis, FM Collier, PU Cameron, WR Holloway, TJ Gough, C Gregorio-King, MA Kirkland, DE Myers
Journal article | 2000 | Clinical Science
Osteoclasts are bone-resorbing cells that are derived from haemopoietic precursors, including cells present in peripheral blood. T..
Characterization of amylin and calcitonin receptor binding in the mouse alpha-thyroid-stimulating hormone thyrotroph cell line.
KJ Perry, M Quiza, DE Myers, M Morfis, G Christopoulos, PM Sexton
Journal article | 1997 | Endocrinology
Recently, a high affinity amylin binding site was identified in the mouse alpha-TSH thyrotroph cell line. In this study, we have c..
Lipoprotein-induced prostacyclin production in endothelial cells and effects of lipoprotein modification.
DE Myers, WN Huang, RG Larkins
Journal article | 1996 | American Journal of Physiology-Cell Physiology
Although lipoprotein modification has been implicated in atherogenesis, the effect of modified forms of lipoproteins on vascular c..
Calcium inflow in cells transfected with cloned rat and porcine calcitonin receptors.
DM Findlay, S Houssami, PM Sexton, CL Brady, TJ Martin, DE Myers
Journal article | 1995 | Biochimica et Biophysica Acta (BBA) - Molecular Cell Research
Ca2+ fluxes were examined in HEK 293 cells stably expressing the rat or porcine calcitonin receptors (CTRs). Calcitonin (CT) rapid..
Truncation of the porcine calcitonin receptor cytoplasmic tail inhibits internalization and signal transduction but increases receptor affinity.
DM Findlay, S Houssami, HY Lin, DE Myers, CL Brady, PK Darcy, K Ikeda, TJ Martin, PM Sexton
Journal article | 1994 | Molecular Endocrinology
A series of mutant porcine calcitonin receptors with progressively truncated carboxy termini have been expressed in COS and HEK 29..
Isoforms of the rat calcitonin receptor: consequences for ligand binding and signal transduction.
S Houssami, DM Findlay, CL Brady, DE Myers, TJ Martin, PM Sexton
Journal article | 1994 | Endocrinology
Two rat calcitonin (CT) receptor isoforms; C1a and C1b, are identical except for the presence of a 37-amino acid insert in the sec..
Stimulation of phosphatidylinositol turnover in adult rat left atria does not involve release of inositol(1,4,5)trisphosphate.
KE Anderson, D Myers, EA Woodcock
Journal article | 1993 | Clinical and Experimental Pharmacology and Physiology
1. The turnover rate of inositol(1,4,5)trisphosphate (Ins(1,4,5)P3) in noradrenaline-stimulated adult rat left atria was calculate..
Honours, Awards and Fellowships
Australian Neuroscience Society
Official Australasian Body For Bone And Mineral Research
Australian and New Zealand Bone and Mineral Society
Doctor of Philosophy
University of Melbourne
Master of Applied Science (Biology)
Royal Melbourne Institute of Technology
Bachelor of Applied Science (Biology)
Royal Melbourne Institute of Technology